Alan Nicholls, Frenderic Raphael, Kevin Dunn, Jonathan Northcroft, P B, John Dugdale, Matthew Wall, Barbara Hall, Lucas Hollweg, R Barber, Jeff Dawson, Gail Emms, Pippa Funnell, N J, Fred Redwood, Jim Munro, Andrew Bell, Helen Davies, Sally Brock, Rob Hughes, Jason Dawe, John Peter, Gideon Garter, Hamish Stevenson, Natalie Ayres, Nigel Bumham, David Wilson, Andrew Longmore, Adam Hathaway, Michael Littlewood, Susan d'Arcy, Gareth Walsh, Frank Whitford, Ivo Tennant, Matthew Davis, Terence Blacker, Caroline Brannigan, Nigel Planer, Kathryn Cooper, P D, Lucy Hughes-Hallett, David Smith, Paul Driver, Neil Wormald, E P, Andrew Sullivan, Clive Davis, Stephen Grey, K R, Andrew Porter, A C, Tony Allen-Mills, Simon Wilde, John O'Brien, D C, Martin James, Tom Walker, Anthony Sattin, Robert Winnett, Claire Harvey, Irwin Stelzer, Adrian Furnham, Robert Hewison, Peter Wilson, Rosie Millard, Stephen Wares, Michel, David Dougill, David Balddiel, Rob Hadgraft, Bob Thompson, Tony Marcus, A Limbert, R Pope, Geraldine Hackett, Richard Clarke, Sue Townsend, Rob Maul, David Hewson, Alistair Weaver, Xavier Rivoire, Paul French, Nigel Deacon, Hugh Canning, Geraldine Hackett Education Correspondent, Andrew Stone, Jeremy Clarkson, Edward Porter, Phil Spencer, Peter Conradi, Victoria Segal, David Cairns, Michael Portillo, Professor Tom Elliott, Stewart Lee, Peter Kemp, Anthony Peregrine, Tara Calishain, Sarah Dempster, Robert Harris, Dave Pollard, Robert Pires, Richard Fletcher, Bob Dylan, Liz Edwards, Gary Fiddes, Peter Oliver, George Perry, Jeremy Guscott, Jonathan Margolis, Colin Miller, John Padgett, Mike Laws, Peter Browm, Paul Ham, Christopher Silvester, Sarah-Kate Templeton, Roger Eglin, D MaCintyre, Paul Donovan, Dr Chris Allen, Mark Espiner, Tom Stubbs, Simon Mills, Chris Woodhead, David Powis, Jasper Gerard, Will Greenwood, Phil Craigic, Emma Thompson, Ann McFerran, Michael Barrows, Nicholas Hellen, Richard Brooks, John Follain, Garth Pearce, Ian Hawkey, Charles Saunders, Julian Corlett, Christopher Morgan, David Leppard, Alex Clark, Paul Durman, Paul Freestone, Milton Jones, Shelley Von Strunckel, Alicia Wyllie, Mark Edwards, Rachel Bridge, Hugh McLlvanney, Stephen Clarke, Kira Cochrane, Norman Sherry, Harriet Perry, Blower, James Brown, Sarah Turner, Achmat Dangor, Jonathan Cook, Christina Lamb, Stephanie Donworth, Michael Palin, Kathy Arnold, S M, Alan Combes, Sean Newsom, Ashlee Simpson, Raymond Keene, Michael Fraser, Cosmo Laandesman, C L, Eva Gronbech, Rod Liddle, Clive Rcuse, Penelope Lively, David Cracknell, Cosmo Landesman, Katrina Manson, Zoe Brennan, Tim Bowler, S B, Dominic O'Connell, Pat Coates, Peter Koenig, Richard Evans, Nick Cain, Louise Armitstead, Stephen Bleach, Adrienne Connors, Natalie Graham, Catherine Wheatley, David Davis, Caroline Donald, Alwyn Collister, Hugh McManners, Fiona Terry, Miranda Seymour, David Walsh, Caroline Gascoigne, Liat Joshi, Jack Grimston, Colin McDowell, Bryan Appleyard, Sarah Keenlyside, Stephen Armstrong, John Elliott, Donovan Winter, Mark Macaskill, Mark Anstead, Nathan Fletcher, Victoria O'brien, N R, Richard Woods, Roland White, Paul Wade, Shane Watson, Abul Taher, Maurice Chittenden, Dr Henry Gyasi, Richard Rae, Mark Franchetti, Joanna Jepson, Ray Hutton, Robert Bottamley, John Neal, Jonathan Leake, Sir Andrew Turnbull Cabinet Secretary and Head of the Home Civil Service, M E, John Crossland, Amanda Craig, Clare Francis, John Harlow, Dileep Premachandran, Yoko Ono, Dipesh Gadher, Michael Collins, Stephen Briggs, John Waples, Conrad Black, A A Gill, Denis Walsh, Matthew Campbell, Lucy West, Brian Highley, David James, Mary Braid, Lois Wilson, Stephen Pettitt, Will Iredale, Karen MacGregor, Jeremy Langmead, T L, Sally Kinnes, Judith Summers, Naomi Caine, Nigel Powell, Daniel Emery, Tony Robinson, Ben Dowell, Minette Marrin, John Aizlewood, Simon Buckland, Mark Hodson, Andrew Frankel, Graham Norwood, Clifford Bishop, Joe Lovejoy, Jonathan Futrell, J P, David Budworth, Bashir Maan, William Lewis Business editor, Andrew Davidson, Patrick Nolan, Hugh Pearman, Dan Cairns, Julian Gray, Stewart Mitchell, David Smith Economics Editor, Rachel De Thame, Penny Perrick, Sarah Baxter, James Willoughby, Matthew Goodman, India Knight, Simon Howard, Nina Goswami, Tom Bower, Barry Newcombe, Nick Faldo, Dominic Rushe, Ben West, Sian Griffiths, Karen Robinson, Adrienne Connore,
... target again Stockport's late comeback halts Swindon Kuipers earns home share Geoff Hurst, 1966 The top ... the leader at the World Golf Championship Cool Bjorn stays in the zone The Dane had one ...
2004 - Gale Group | Sunday Times HA GDA
Robert A. Pedowitz, David H. Gershuni, Michael J. Botte, Scott D. Kuiper, Björn L. Rydevik, Alan R. Hargens,
Use of the lowest possible cuff inflation pressure should minimize the pathogenic effects of compression beneath the pneumatic tourniquet. Curved tourniquets (designed to fit conically shaped limbs) and wider tourniquets were associated with significantly lower arterial occlusion pressure (AOP) than standard, straight tourniquets on the arms and legs of 26 normal volunteers. These tourniquets were used with an integrated tourniquet inflation system in 29 upper-extremity and 31 lower-extremity surgeries. ...
Tópico(s): Muscle and Compartmental Disorders
1993 - Lippincott Williams & Wilkins | Clinical Orthopaedics and Related Research
Jesse W.P. Kuiper, Jolanda M. A. Hogervorst, Bjorn L. Herpers, Astrid D. Bakker, Jenneke Klein‐Nulend, Peter A. Nolte, Bastiaan P. Krom,
In this in vitro study the effect of XZ.700, a new endolysin, on methicillin resistant Staphylococcus aureus (MRSA) biofilms grown on titanium was evaluated. Biofilms of S. aureus USA300 were grown statically and under flow, and treatment with XZ.700 was compared with povidone-iodine (PVP-I) and gentamicin. To evaluate the cytotoxic effects of XZ.700 and derived biofilm lysates, human osteocyte-like cells were exposed to biofilm supernatants, and metabolism and proliferation were quantified. XZ.700 ...
Tópico(s): Bacterial biofilms and quorum sensing
2021 - Taylor & Francis | Biofouling
Jan J. Kuiper, Wolf M. Mooij, Luca Bragazza, Bjorn J. M. Robroek,
Peatlands are important sinks for atmospheric carbon (C), yet the role of plant functional types (PFTs) for C sequestration under climatic perturbations is still unclear. A plant-removal experiment was used to study the importance of vascular PFTs for the net ecosystem CO2 exchange (NEE) during (i.e., resistance) and after (i.e., recovery) an experimental drought. The removal of PFTs caused a decrease of NEE, but the rate differed between microhabitats (i.e., hummocks and lawns) and the type of PFTs. ...
Tópico(s): Botany and Plant Ecology Studies
2013 - Wiley | Ecology
Hélène Duez, Jelske N. van der Veen, Christian Duhem, Benoît Pourcet, Thierry Touvier, Coralie Fontaine, Bruno Derudas, Eric Baugé, Rick Havinga, Vincent W. Bloks, Henk Wolters, Fjodor H. van der Sluijs, Björn Vennström, Folkert Kuipers, Bart Staels,
Background & Aims: Conversion into bile acids represents an important route to remove excess cholesterol from the body. Rev-erbα is a nuclear receptor that participates as one of the clock genes in the control of circadian rhythmicity and plays a regulatory role in lipid metabolism and adipogenesis. Here, we investigate a potential role for Rev-erbα in the control of bile acid metabolism via the regulation of the neutral bile acid synthesis pathway. Methods: Bile acid synthesis and CYP7A1 gene expression ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2008 - Elsevier BV | Gastroenterology
J.A. Dieleman, Francel Verstappen, Björn Nicander, D. Kuiper, Elisabeth Tillberg, J. Tromp,
To assess the role of endogenous cytokinins in growth and development of Rosa hybrida , their concentrations in bleeding sap and in roots, stem, leaves, axillary shoots and bottom breaks in three stages of development were quantified. Cytokinins were purified by means of immunoaffinity chromatography and HPLC, and identified by retention time, UV spectrum and GC‐MS. The major translocation form in the xylem was zeatin riboside (ZR). In all mature tissues, cytokinins of the zeatin‐type were predominant, ...
Tópico(s): Plant Reproductive Biology
1997 - Wiley | Physiologia Plantarum
Raoul Kuiper, Rocío F. Cantón, P.E.G. Leonards, Bjørn Munro Jenssen, Marco Dubbeldam, P.W. Wester, Martin van den Berg, Joseph G. Vos, A. Dick Vethaak,
Tetrabromobisphenol A (TBBPA) and hexabromocyclododecane (HBCD) are widely used flame retardants that have increasingly been found as contaminants in the aquatic environment. In the present study, European flounder (Platichthys flesus) were chronically exposed to TBBPA; (105 days) and HBCD (78 days), in a wide range including environmentally relevant concentrations. TBBPA was administered via the water, whereas HBCD was administered in food and sediment, or in sediment alone. Chemical analysis of muscle ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2007 - Elsevier BV | Ecotoxicology and Environmental Safety
Björn Schneider, Klaudia F. Kuiper, Onno Postma, J.R. Wijbrans,
Magnetic sector mass spectrometers dominate the field of 40Ar/39Ar geochronology. Recent advances in quadrupole mass spectrometer technology, especially improvements in resolution, have increased the performance of these instruments to the extent that they can be used for isotopic determinations. We describe a triple filter quadrupole mass spectrometer (Hiden HAL 3F Series Pulse Ion Counting Triple Filter QMS) linked to an automated furnace extraction and cleaning system dedicated to 40Ar/39Ar incremental ...
Tópico(s): Isotope Analysis in Ecology
2009 - Elsevier BV | Quaternary Geochronology
J.R. Wijbrans, Björn Schneider, Klaudia F. Kuiper, Sonia Calvari, Stefano Branca, Emanuela De Beni, Gianluca Norini, Rosa Anna Corsaro, Lucia Miraglia,
Absolute chronologies of active volcanoes and consequently timescales for eruptive behaviour and magma production form a quantitative basis for understanding the risk of volcanoes. Surprisingly, the youngest records in the geological timescale often prove to be the most elusive when it comes to isotopic dating. Absolute Holocene volcanic records almost exclusively rely on 14C ages measured on fossil wood or other forms of biogenic carbon. However, on volcanic flanks, fossil carbon is often not preserved, ...
Tópico(s): earthquake and tectonic studies
2010 - Elsevier BV | Quaternary Geochronology
T Kuipers, G. Björn Stark, G. Spilker,
Tópico(s): Breast Cancer Treatment Studies
1992 - Springer Science+Business Media | European Journal of Plastic Surgery
Hilde Mellegård, Ákos T. Kovács, Toril Lindbäck, Bjørn E. Christensen, Oscar P. Kuipers, Per Einar Granum,
The antibacterial activity of the polysaccharide chitosan towards different bacterial species has been extensively documented. The response mechanisms of bacteria exposed to this biopolymer and the exact molecular mechanism of action, however, have hardly been investigated. This paper reports the transcriptome profiling using DNA microarrays of the type-strain of Bacillus cereus (ATCC 14579) exposed to subinhibitory concentrations of two water-soluble chitosan preparations with defined chemical characteristics ( ...
Tópico(s): Probiotics and Fermented Foods
2011 - Public Library of Science | PLoS ONE
Aniek Hebinck, Monika Zurek, T.J. Achterbosch, Björn Forkman, Anneleen Kuijsten, Marijke Kuiper, Birgit Nørrung, P. van ’t Veer, Adrian Leip,
Growing acknowledgement that food systems require transformation, demands comprehensive sustainability assessments that can support decision-making and sustainability governance. To do so, assessment frameworks must be able to make trade-offs and synergies visible and allow for inclusive negotiation on food system outcomes relevant to diverse food system actors. This paper reviews literature and frameworks and builds on stakeholder input to present a Sustainability Compass made up of a comprehensive ...
Tópico(s): Organic Food and Agriculture
2021 - Elsevier BV | Global Food Security
Mário Dinis‐Ribeiro, Miguel Areia, Annemarie de Vries, Ricardo Marcos‐Pinto, Matilde Monteiro‐Soares, Anthony O’Connor, Carina Pereira, Pedro Pimentel‐Nunes, Ricardo Cruz‐Correia, Arzu Ensarı, Jean‐Marc Dumonceau, José Carlos Machado, Guilherme Macedo, Peter Malfertheiner, Tamara Matysiak‐Budnik, Françis Mégraud, Kazumasa Miki, Colm O’Morain, Richard M. Peek, Thierry Ponchon, Ari Ristimäki, Björn Rembacken, Fátima Carneiro, E.J. Kuipers,
Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common and are associated with an increased risk for gastric cancer. In the absence of guidelines, there is wide disparity in the management of patients with these premalignant conditions. The European Society of Gastrointestinal Endoscopy (ESGE), the European Helicobacter Study Group (EHSG), the European Society of Pathology (ESP) and the Sociedade Portuguesa de Endoscopia Digestiva (SPED) have therefore combined ...
Tópico(s): Gastrointestinal disorders and treatments
2011 - Thieme Medical Publishers (Germany) | Endoscopy
Mário Dinis‐Ribeiro, Miguel Areia, Annemarie C. de Vries, Ricardo Marcos‐Pinto, Matilde Monteiro‐Soares, Anthony O’Connor, Carina Pereira, Pedro Pimentel‐Nunes, Ricardo Cruz‐Correia, Arzu Ensarı, Jean‐Marc Dumonceau, José Carlos Machado, Guilherme Macedo, Peter Malfertheiner, Tamara Matysiak‐Budnik, Françis Mégraud, Kazumasa Miki, Colm O’Morain, Richard M. Peek, Thierry Ponchon, Ari Ristimäki, Björn Rembacken, Fátima Carneiro, Ernst J. Kuipers,
Tópico(s): Gastrointestinal disorders and treatments
2011 - Springer Science+Business Media | Virchows Archiv
Irene Voldsbekk, Atle Bjørnerud, Inge Rasmus Groote, Nathalia Zak, Daniël Roelfs, Ivan I. Maximov, Oliver Geier, Paulina Due‐Tønnessen, Erlend Bøen, Yvonne S. Kuiper, Lise-Linn Løkken, Marie Strømstad, Taran Y. Blakstvedt, Bjørn Bjorvatn, Ulrik Fredrik Malt, Lars T. Westlye, Torbjørn Elvsåshagen, Håkon Grydeland,
Cortical microstructure is influenced by circadian rhythm and sleep deprivation, yet the precise underpinnings of these effects remain unclear. The ratio between T1-weighted and T2-weighted magnetic resonance images (T1w/T2w ratio) has been linked to myelin levels and dendrite density and may offer novel insight into the intracortical microstructure of the sleep deprived brain. Here, we examined intracortical T1w/T2w ratio in 41 healthy young adults (26 women) before and after 32 h of either sleep ...
Tópico(s): Sleep and related disorders
2022 - Springer Nature | Translational Psychiatry
Thomas Lundåsen, Matteo Pedrelli, Bodil Bjørndal, Björn Rozell, Raoul Kuiper, Lena Burri, Chiara Pavanello, Marta Turri, Jon Skorve, Rolf K. Berge, Stefan E.H. Alexson, Veronika Tillander,
Tetradecylthioacetic acid (TTA) is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including activation of peroxisome proliferator activated receptors (PPARs) with preference for PPARα. This study investigated the effects of TTA on lipid and lipoprotein metabolism in the intestine and liver of mice fed a high fat diet (HFD). Mice receiving HFD supplemented with 0.75% (w/w) ...
Tópico(s): Drug Transport and Resistance Mechanisms
2020 - Public Library of Science | PLoS ONE
Hege Andersen Amofah, Anders Broström, Bengt Fridlund, Bjørn Bjorvatn, Rune Haaverstad, Karl Ove Hufthammer, Karel KJ Kuiper, Anette Hylen Ranhoff, Tone M. Norekvål,
Octogenarians with aortic stenosis are an increasing population of patients admitted for surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI). Although adequate sleep is important after illness and surgery, it has scarcely been studied in the immediate postoperative phase. To determine and compare the nature of self-reported sleep and insomnia, and recorded sleep–wake patterns in octogenarians during the in-hospital postoperative phase after SAVR or TAVI. A prospective ...
Tópico(s): Sleep and related disorders
2015 - Oxford University Press | European Journal of Cardiovascular Nursing
Claire Palles, Laura Chegwidden, Xinzhong Li, John M. Findlay, Garry Farnham, Francesc Castro-Giner, Maikel P. Peppelenbosch, Michal Kováč, Claire Adams, Hans Prenen, Sarah Briggs, Rebecca Harrison, S. Sanders, David MacDonald, Chris Haigh, Art Tucker, Sharon Love, Manoj Nanji, John de Caestecker, David Ferry, B J Rathbone, Julie Hapeshi, Hugh Barr, Paul Moayyedi, Peter J. Watson, Barbara Zietek, Neera Maroo, Laura Gay, Timothy J. Underwood, Lisa Boulter, Hugh McMurtry, David Gabriel Monk, Praful Patel, Krish Ragunath, David Al Dulaimi, Iain Murray, Konrad Koss, Andrew Veitch, Nigel Trudgill, Chuka Nwokolo, Björn Rembacken, Paul Atherfold, Elaine Green, Yeng Ang, Ernst J. Kuipers, W H Chow, Stuart Paterson, Sudarshan Kadri, Ian Beales, Charles Grimley, Paul D. Mullins, Conrad Beckett, Mark Farrant, Andrew Dixon, Sean G. Kelly, Matthew E. Johnson, Saj Wajed, Anjan Dhar, Elinor J. Sawyer, Rebecca Roylance, Lynn Onstad, Marilie D. Gammon, Douglas A. Corley, Nicholas J. Shaheen, Nigel C. Bird, Laura J. Hardie, Brian J. Reid, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H. Wu, Alan G. Casson, Rebecca C. Fitzgerald, David C. Whiteman, Harvey A. Risch, David Levine, Tom L. Vaughan, Auke P. Verhaar, Jan Van den Brande, Eelke L.A. Toxopeus, Manon C.W. Spaander, Bas P. L. Wijnhoven, Luc J. W. van der Laan, Kausilia K. Krishnadath, Cisca Wijmenga, Gosia Trynka, Ross McManus, John V. Reynolds, Jacintha O’Sullivan, Padraic MacMathúna, Sarah A. McGarrigle, Dermot Kelleher, Séverine Vermeire, Isabelle Cleynen, Raf Bisschops, Ian Tomlinson, Janusz Jankowski,
Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA region) and on 16q23, where the closest protein-coding gene is FOXF1. Subsequently, the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON) identified risk loci for BE and esophageal adenocarcinoma near CRTC1 and BARX1, and within 100 kb of FOXP1. We aimed to identify further SNPs that increased ...
Tópico(s): Epigenetics and DNA Methylation
2014 - Elsevier BV | Gastroenterology
Annett Janusch, Margot D.O. van der Kamp, Krys Bottrill, Barbara Grune, David C. Anderson, Björn Ekwall, Michelle Howald, Roman Kolar, Hans J.D. Kuiper, Jean Larson, G. Loprieno, Ursula G. Sauer, A. J. Smith, J.B.F. van der Valk,
1997 - SAGE Publishing | Alternatives to Laboratory Animals
Philipp Kasper, Jaco Selle, Christina Vohlen, Rebecca Wilke, Celien Kuiper-Makris, Oleksiy Klymenko, Inga Bae‐Gartz, Charlotte Schömig, Alexander Quaas, Björn Schumacher, Münevver Demir, Martin Bürger, Sonja Lang, Anna Martin, Hans‐Michael Steffen, Tobias Goeser, Jörg Dötsch, Miguel A. Alejandre Alcázar,
Maternal obesity predisposes for hepato-metabolic disorders early in life. However, the underlying mechanisms causing early onset dysfunction of the liver and metabolism remain elusive. Since obesity is associated with subacute chronic inflammation and accelerated aging, we test the hypothesis whether maternal obesity induces aging processes in the developing liver and determines thereby hepatic growth. To this end, maternal obesity was induced with high-fat diet (HFD) in C57BL/6N mice and male offspring ...
Tópico(s): Adipose Tissue and Metabolism
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Cesare Hassan, Michael Bretthauer, Michał F. Kamiński, Marcin Polkowski, Björn Rembacken, Brian P. Saunders, Robert Benamouzig, Øyvind Holme, S. Green, Teaco Kuiper, Riccardo Marmo, Mahmoud Omar, Lucio Petruzziello, Cristiano Spada, Angelo Zullo, Jean‐Marc Dumonceau,
Background and aim: This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the choice amongst regimens available for cleansing the colon in preparation for colonoscopy. Methods: This Guideline is based on a targeted literature search to evaluate the evidence supporting the use of bowel preparation for colonoscopy. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was adopted to define the strength of recommendation ...
Tópico(s): Colorectal Cancer Surgical Treatments
2013 - Thieme Medical Publishers (Germany) | Endoscopy
Konrad Aden, Florian Tran, Go Ito, Raheleh Sheibani‐Tezerji, Simone Lipinski, J. W. Kuiper, Markus Tschurtschenthaler, Svetlana Saveljeva, Joya Bhattacharyya, Robert Häsler, Kareen Bartsch, Anne Luzius, Marlene Jentzsch, Maren Falk‐Paulsen, Stephanie T. Stengel, Lina Welz, Robin Schwarzer, Björn Rabe, Winfried Barchet, Stefan Krautwald, Gunther Hartmann, Manolis Pasparakis, Richard S. Blumberg, Stefan Schreiber, Arthur Kaser, Philip Rosenstiel,
A coding variant of the inflammatory bowel disease (IBD) risk gene ATG16L1 has been associated with defective autophagy and deregulation of endoplasmic reticulum (ER) function. IL-22 is a barrier protective cytokine by inducing regeneration and antimicrobial responses in the intestinal mucosa. We show that ATG16L1 critically orchestrates IL-22 signaling in the intestinal epithelium. IL-22 stimulation physiologically leads to transient ER stress and subsequent activation of STING-dependent type I interferon ( ...
Tópico(s): Autophagy in Disease and Therapy
2018 - Rockefeller University Press | The Journal of Experimental Medicine
Konrad Aden, Florian Tran, Markus Tschurtschenthaler, Kareen Bartsch, Raheleh Sheibani‐Tezerji, Anne Luzius, Maren Paulsen, J. W. Kuiper, Björn Rabe, Richard S. Blumberg, Stefan Schreiber, Arthur Kaser, Philip Rosenstiel,
Tópico(s): Helicobacter pylori-related gastroenterology studies
2016 - Elsevier BV | Gastroenterology
Michiel Kleerebezem, Jos Boekhorst, Richard van Kranenburg, Douwe Molenaar, Oscar P. Kuipers, Rob J. Leer, Renato Tarchini, Sander Peters, H. Sandbrink, Mark Fiers, Willem J. Stiekema, R.M. Klein Lankhorst, Peter A. Bron, Sally M. Hoffer, M.N. Nierop Groot, Robert Kerkhoven, Maaike de Vries, Björn M. Ursing, Willem M. de Vos, Roland J. Siezen,
The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes. Putative biological functions could be assigned to 2,120 (70%) of the predicted proteins. Consistent with the classification of L. plantarum as a facultative heterofermentative lactic acid bacterium, the genome encodes all enzymes required for the glycolysis ...
Tópico(s): Bacterial Genetics and Biotechnology
2003 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Produção Nacional
Revisado por pares
Alexey Dudnik, A. Filipa Almeida, Ricardo Andrade, Bárbara Gorziza Ávila, Pilar Bañados, Diane Barbay, Jean-Étienne Bassard, Mounir Benkoulouche, Michael Bott, Adelaide Braga, Dario Breitel, Rex Brennan, Laurent Bulteau, Céline Chanforan, Inês Costa, Rafael S. Costa, Mahdi Doostmohammadi, N. Faria, Chengyong Feng, Armando Fernandes, Patrícia Ferreira, R. Ferro, Alexandre Foito, Sabine Freitag, Gonçalo Garcia, Paula Gaspar, Joana Godinho-Pereira, Björn Hamberger, András Hartmann, Harald Heider, Carolina Jardim, Alice Julien-Laferrière, Nicolai Kallscheuer, Wolfgang Kerbe, Oscar P. Kuipers, Shanshan Li, Nicola Love, Alberto Marchetti-Spaccamela, Jan Marienhagen, Cathie Martin, Arnaud Mary, Vincent Mazurek, Camillo Meinhart, David Méndez Sevillano, Regina Menezes, Michael Næsby, Morten H. H. Nørholm, Finn T. Okkels, Joana Oliveira, Marcel Ottens, Delphine Parrot, Lei Pei, Isabel Rocha, Rita Rosado-Ramos, C. Rousseau, Marie-France Sagot, Cláudia Nunes dos Santos, Markus Schmidt, Т. В. Шеленга, Louise Shepherd, Ana Rita Silva, Marcelo Silva, Olivier Simon, Steen G. Stahlhut, Ana Solopova, Artëm Sorokin, Derek Stewart, Leen Stougie, Shang Su, Vera Thole, О. А. Тихонова, Martin Trick, Philippe Vain, André Veríssimo, Ana Vila-Santa, Susana Vinga, Michael Vogt, Liangsheng Wang, Lijin Wang, Wei Wei, Sandra Youssef, Ana Rute Neves, Jochen Förster,
BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization ...
Tópico(s): Microbial Metabolism and Applications
2017 - Springer Science+Business Media | Phytochemistry Reviews
Gert Sclep, Joke Allemeersch, Robin Liechti, Björn De Meyer, Jim Beynon, Rishikesh P. Bhalerao, Yves Moreau, Wilfried Nietfeld, Jean‐Pierre Renou, Philippe Reymond, Martin Kuiper, Pierre Hilson,
Abstract Background The Complete Arabidopsis Transcript MicroArray (CATMA) initiative combines the efforts of laboratories in eight European countries [1] to deliver gene-specific sequence tags (GSTs) for the Arabidopsis research community. The CATMA initiative offers the power and flexibility to regularly update the GST collection according to evolving knowledge about the gene repertoire. These GST amplicons can easily be reamplified and shared, subsets can be picked at will to print dedicated arrays, ...
Tópico(s): Chromosomal and Genetic Variations
2007 - BioMed Central | BMC Bioinformatics
Maria A. Hoelzl, Karin Heby-Henricson, Ganna Bilousova, Björn Rozell, Raoul Kuiper, Maria Kasper, Rune Toftgård, Stephan Teglund,
The hedgehog (Hh) signaling pathway plays fundamental roles during embryonic development and tumorigenesis. Previously, we have shown that ablation of the tumor suppressor and negative regulator, Suppressor of fused (Sufu), within this pathway causes embryonic lethality around E9.5 in the mouse. In this study, we examine how lack of Sufu influences early cell fate determination processes. We established embryonic stem cell (ESC) lines from preimplantation Sufu−/− and wild-type mouse embryos and show ...
Tópico(s): Developmental Biology and Gene Regulation
2015 - Mary Ann Liebert, Inc. | Stem Cells and Development
Molly Went, Ben Kinnersley, Amit Sud, David C. Johnson, Niels Weinhold, Asta Försti, Mark van Duin, Giulia Orlando, Jonathan S. Mitchell, Rowan Kuiper, Brian A. Walker, Walter M. Gregory, Per Hoffmann, Graham Jackson, Markus M. Nöthen, Miguel Inácio da Silva Filho, Hauke Thomsen, Annemiek Broyl, Faith E. Davies, Unnur Þorsteinsdóttir, Markus Hansson, Martin Kaiser, Pieter Sonneveld, Hartmut Goldschmidt, Kári Stéfansson, Kari Hemminki, Björn Nilsson, Gareth J. Morgan, Richard S. Houlston,
While genome-wide association studies (GWAS) of multiple myeloma (MM) have identified variants at 23 regions influencing risk, the genes underlying these associations are largely unknown. To identify candidate causal genes at these regions and search for novel risk regions, we performed a multi-tissue transcriptome-wide association study (TWAS). GWAS data on 7319 MM cases and 234,385 controls was integrated with Genotype-Tissue Expression Project (GTEx) data assayed in 48 tissues (sample sizes, N = 80– ...
Tópico(s): Lymphoma Diagnosis and Treatment
2019 - BioMed Central | Human Genomics
Björn Schneider, Klaudia F. Kuiper, Ken Mai, J. Foeken, Finlay M. Stuart, J.R. Wijbrans,
In situ Terrestrial Cosmogenic Nuclides (hereafter TCNs) are increasingly important for absolutely dating terrestrial events and processes. This study aimed at improving our knowledge of the production rate of Terrestrial Cosmogenic 3He formed in situ in rock surfaces at low latitude and sea level as well as re-evaluation of the Canary Islands as a calibration site for TCNs. For this purpose, we sampled basaltic lava flows from some of the youngest and yet undated volcanic sites and used the 40Ar/ ...
Tópico(s): Geomagnetism and Paleomagnetism Studies
2013 - Elsevier BV | Quaternary Geochronology
Stephan Michalik, Alexander Reder, Björn Richts, Patrick Faßhauer, Ulrike Mäder, Tiago Pedreira, Anja Poehlein, Auke J. van Heel, Amanda Y. van Tilburg, Josef Altenbuchner, Anika Klewing, Daniel R. Reuß, Rolf Daniel, Fabian M. Commichau, Oscar P. Kuipers, Leendert W. Hamoen, Uwe Völker, Jörg Stülke,
To better understand cellular life, it is essential to decipher the contribution of individual components and their interactions. Minimal genomes are an important tool to investigate these interactions. Here, we provide a database of 105 fully annotated genomes of a series of strains with sequential deletion steps of the industrially relevant model bacterium Bacillus subtilis starting with the laboratory wild type strain B. subtilis 168 and ending with B. subtilis PG38, which lacks approximately ...
Tópico(s): Bacterial Genetics and Biotechnology
2021 - American Chemical Society | ACS Synthetic Biology