
Mariana Duarte Bona, Pedro Medeiros, Ana Karolina Silva dos Santos, Thiago M. Freitas, Mara A. Prata, Herlice N. Veras, M.S.M.G. Amaral, Daniel Pereira de Oliveira, Alexandre Havt, Aldo Â. M. Lima,
Shigella/Enteroinvasive Escherichia coli (EIEC) pathotype is a major enteropathogen associated with diarrhea and malnutrition in children from developing countries. This study aimed to correlate Shigella/EIEC virulence-related genes (VRGs) with clinical symptoms, nutritional status and coenteropathogens in children from the Brazilian semiarid region. We designed a case-control study of community diarrhea in six cities of the Brazil semiarid region with 1200 children aging 2–36 months. Standardized ...
Tópico(s): Salmonella and Campylobacter epidemiology
2019 - Elsevier BV | International Journal of Medical Microbiology

Mariana Duarte Bona, Carlos Henrique de Medeiros Torres, Severina Carla Vieira Cunha Lima, Ana Heloneida de Araújo Morais, Aldo Â. M. Lima, Bruna Leal Lima Maciel,
Altered intestinal barrier permeability has been associated with obesity and its metabolic and inflammatory complications in animal models. The purpose of this systematic review is to assess the evidence regarding the association between obesity with or without Metabolic Syndrome (MetS) and alteration of the intestinal barrier permeability in humans. A systematic search of the studies published up until April 2022 in Latin America & Caribbean Health Sciences Literature (LILACS), PubMed, Scopus, Embase, ...
Tópico(s): Barrier Structure and Function Studies
2022 - Multidisciplinary Digital Publishing Institute | Nutrients

Lucas de Souza Nespeca, Hellen Fernanda da Silva Paulino, Tamires Barlati Vieira da Silva, Evandro Bona, Fernanda Vitória Leimann, Leila Larisa Medeiros Marques, Flávia Aparecida Reitz Cardoso, Adriana Aparecida Droval, Renata Hernandez Barros Fuchs,
Summary Gluten‐free bakery products usually use rice flour as substitute for wheat flour. This paper aims to evaluate whether and how the substitution of rice flour for sorghum and teff flour changes the overall acceptance, texture and sensory profile of gluten‐free chocolate cakes. An experimental design composed of three factors (rice, sorghum and teff flours) was developed, and formulations were analysed by acceptance test and fibre content. Four formulations were submitted to sensory descriptive ...
Tópico(s): Agricultural and Food Sciences
2020 - Wiley | International Journal of Food Science & Technology

Mariana Duarte Bona, Carlos Henrique de Medeiros Torres, Severina Carla Vieira Cunha Lima, Aldo Â. M. Lima, Bruna Leal Lima Maciel,
Introduction Intestinal barrier function is dependent on the structure and function of intestinal epithelial cells and paracellular pathway. The derangement of the intestinal barrier function can originate from conditions involving local and systemic chronic inflammation and metabolic diseases such as obesity and metabolic disorders. This study aims to describe a systematic review protocol investigating if obesity with or without metabolic syndrome is associated with an altered intestinal barrier ...
Tópico(s): Diet and metabolism studies
2021 - BMJ | BMJ Open

Kátia Raquel Weber, Paula Benetti, Álvaro Della Bona, Pedro Henrique Corazza, Juliana Arisi Medeiros, Ediléia Lodi, Márcia Borba,
Variables involving the indication, manufacturing, and clinical use of ceramic restorations make the standardization of in vitro studies a challenge and raise questions as to the clinical validity of the resulting data.The purpose of this in vitro study was to assess the effect of piston material on the fracture behavior of ceramics tested under compressive load.Two ceramics were evaluated: a lithium disilicate-based glass-ceramic (D) and a feldspathic porcelain (P). Plate-shaped ceramic specimens ( ...
Tópico(s): Dental Implant Techniques and Outcomes
2018 - Elsevier BV | Journal of Prosthetic Dentistry

Fabricio Marcelo Cevallos González, Erika Michele dos Santos Araújo, Maria Regina Lorenzetti Simionato, Luciana Kfouri Siriani, Ana del Carmen Armas Vega, Igor Studart Medeiros, Adriana Bona Matos,
In vitro effect of 1% theobromine addition on the physical and chemical properties of conventional glass ionomer (GIC) cement was investigated. Conventional GIC (GIC-C) and 1% theobromine added to GIC (GIC-THEO) specimens were compared regarding the microhardness (n = 10), sorption (n = 5), solubility (n = 5), color change (n = 10), fluoride release in saliva (n = 10) and the amount of biofilm deposition (n = 20). Compared against conventional GIC, adding 1% theobromine increased microhardness (p < 0.05), while its sorption, ...
Tópico(s): Oral microbiology and periodontitis research
2019 - Springer Nature | Progress in Biomaterials

Eduardo Bona Safe de Matos, Jorge Katsumi Niyama, Luiz Medeiros de Araújo Neto, Matheus de Mendonça Marques,
The analysis of congresses, scientific journals and scientific production is held in different areas of science, with objective of understanding the authors’ profile, the production characteristics or evaluate those qualities. Despite using different methods and tools, the objectives commonly propose to develop the science and characterization of the production in different areas. This paper is aimed with two objectives related to two different areas of the bibliometrics, evaluative and descriptive, ...
Tópico(s): Education and Public Policy
2012 - UNIVERSIDADE ESTADUAL DE MARINGÁ | Enfoque Reflexão Contábil

Renata Hernandez Barros Fuchs, Ricardo Pereira Ribeiro, Makoto Matsushita, Ailey Aparecida Coelho Tanamati, Cristiane Canan, Evandro Bona, Leila Larisa Medeiros Marques, Adriana Aparecida Droval,
The stability of tilapia croquette mixtures was evaluated for 240 days, through analyses of water activity (aw), lipid oxidation (TBARS) and sensory and microbiological assays. The control mixture was composed of tilapia mince, wheat and rye flours and seasonings while the enriched mixture also contained flaxseed flour. Aw increased significantly over time, from 0.1666 to 0.5392 for the control mixture and from 0.0554 to 0.5415 for the enriched mixture. TBARS values increased from 0.08 to 0.38 mg ...
Tópico(s): Microencapsulation and Drying Processes
2015 - Taylor & Francis | CyTA - Journal of Food
L. A. Medeiros, G. Perla Menzala,
We consider the problem $u_t - u_{xx} + uu_x = 0$ in $ - \infty < x$, $t < \infty $ with initial data at $t = 0$ which is 1-periodic and the boundary condition $u(x + 1,t) = u(x,t)$ for all x, t; proving the existence and uniqueness of the solutions of such a problem. We use the semi-discrete approach together with the energy method.
Tópico(s): Nonlinear Photonic Systems
1977 - Society for Industrial and Applied Mathematics | SIAM Journal on Mathematical Analysis

E.S. Lopes, William Cardoso Maciel, Pedro Henrique Quintela Soares de Medeiros, Mariana Duarte Bona, Alexandre Havt, S.V.G. Lima, Fernanda Conceição Gaio, Régis Siqueira de Castro Teixeira,
ABSTRACT: Diarrheagenic Escherichia coli (DEC) are considered one of the major causes of human diarrhea in developing countries. Some studies have pointed wild birds as important reservoirs for these pathogens. However, scarce species from the Psittaciformes order have been investigated. This study aimed to evaluate the presence of DEC strains in Psittaciformes from illegal wildlife trade. A total of 78 E. coli strains isolated from cloacal swab samples of 167 Psittaciformes in the Ceará State, Brazil, ...
Tópico(s): Viral gastroenteritis research and epidemiology
2018 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira

J. Límaco, H. R. Clark, L. A. Medeiros,
The objective of this paper is to establish existence, uniqueness and regularity of solutions for a mixed problem associated with equations of Benjamin–Bona–Mahony type in a domain Q^ with moving boundary. The technique, to show the existence of solutions, consists in transforming Q^ into a cylinder Q by using a diffeomorphism Tt and to apply in Q the Faedo–Galerkin method in the transformed mixed problem. The uniqueness of solutions is proved by using the energy method in the non-cylindrical domain ...
Tópico(s): Differential Equations and Boundary Problems
2004 - Elsevier BV | Nonlinear Analysis

J. Límaco, H. R. Clark, Lis Cardoso Marinho Medeiros,
The objective of this paper is to establish existence, uniqueness and regularity of solutions for a mixed problem associated with equations of Benjamin–Bona–Mahony type in a domain Q^ with moving boundary. The technique, to show the existence of solutions, consists in transforming Q^ into a cylinder Q by using a diffeomorphism Tt and to apply in Q the Faedo–Galerkin method in the transformed mixed problem. The uniqueness of solutions is proved by using the energy method in the non-cylindrical domain ...
Tópico(s): Nonlinear Partial Differential Equations
2004 - Elsevier BV | Nonlinear Analysis

Ana Karolina Silva dos Santos, Pedro Henrique Quintela Soares de Medeiros, Mariana Duarte Bona, Mara de Moura Gondim Prata, M.S.M.G. Amaral, Herlice N. Veras, Rafaela C. Pankov, Samilly Albuquerque Ribeiro, Paloma A. Cavalcante, Thiago M. Freitas, Rafhaella D. G. Gondim, Daniel Maia Nogueira de Oliveira, Natália K. F. M. Melo, Alexandre Havt, Aldo Â. M. Lima,
Enteropathogenic Escherichia coli (EPEC) is a major cause of diarrhea in children from developing countries and presents high genetic variability. We aimed to characterize the EPEC virulence-related gene (VRG) distribution and copathogens associated with diarrhea and nutrition-related outcomes in children from the low-income Brazilian semiarid region. A cross-sectional case-control study of diarrhea was conducted in 1,191 children aged 2 to 36 months from the northeast region of Brazil. Stool samples ...
Tópico(s): Child Nutrition and Water Access
2019 - American Society for Microbiology | Journal of Clinical Microbiology

Antônio de Pádua Marques da Fonseca, Sebastião Honório Bona, Wanda Silveira M. da Fonseca, Francisco Soares Campelo, Prisco Medeiros de Melo Rego,
A mucinose follicular (MuF), também chamada de alopecia mucinosa, é mucinose cutânea caracterizada pelo acúmulo de mucina no folículo pilossebáceo. As mucinoses têm duas formas de apresentação: uma idiopática ou primária, e outra sintomática ou associada a diversos processos benignos e malignos. Os autores apresentam um caso de mucinose folicular primária e fazem breve revisão do assunto. Trata-se de uma paciente de 26 anos de idade, com placa eritematosa recoberta por fina descamação, alopécica ...
Tópico(s): Autoimmune Bullous Skin Diseases
2002 - Elsevier BV | Anais Brasileiros de Dermatologia

Geovana Teixeira de Castro, Luiza Pelinson Tridapalli, Angélica Maria Delovo Fernandes, Evandro Bona, Fernanda Vitória Leimann, Adriana Aparecida Droval, Flávia Aparecida Reitz Cardoso, Leila Larisa Medeiros Marques, Nelson Consolin Filho, Renata Hernandez Barros Fuchs,
Sensory quality is very important to determine the acceptance of food by consumers, and it is essential to identify the sensory attributes that contribute to food acceptability. This paper aimed to identify the attributes that contribute to the sensory acceptance of cookies containing rice, sorghum, and teff flour. The formulations were subjected to sensory descriptive analysis (Flash Profile) to describe the cookie samples. The substitution of wheat flour for sorghum and teff flour did not affect ...
Tópico(s): Consumer Attitudes and Food Labeling
2021 - Wiley | Journal of Food Processing and Preservation

José Gilberto Sousa Medeiros, Claudine Maria de Bona, Francine Lorena Cuquel, Luiz Antônio Biasi,
ABSTRACT: Evaluation of yield performance is important to find the most adapted blueberry cultivars in a particular region. This research aimed to evaluate the flowering and hasvesting periods, the production per plant, and fruit quality of eight rabbiteye blueberry cultivars (Aliceblue, Bluebelle, Bluegem, Briteblue, Climax, Delite, Powderblue, and Woodard) and two highbush blueberries (Georgiagem and O’Neal), in mild winter conditions in Pinhais-PR. Flowering and harvesting periods, production, ...
Tópico(s): Horticultural and Viticultural Research
2017 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural

Pedro Henrique Quintela Soares de Medeiros, Aldo Â. M. Lima, Marjorie Moreira Guedes, Alexandre Havt, Mariana Duarte Bona, Luís Rey, Alberto M. Soares, Richard L. Guerrant, Bernhard H. Weigl, Ila Fernanda Nunes Lima,
Molecular characterization of virulence and antimicrobial resistance profiles were determined for Shigella species isolated from children with diarrhea in Fortaleza, Brazil. Fecal specimens were collected along with socioeconomic and clinical data from children with moderate to severe diarrhea requiring emergency care. Shigella spp. were isolated by standard microbiological techniques, and we developed 4 multiplex polymerase chain reaction assays to detect 16 virulence-related genes (VRGs). Antimicrobial ...
Tópico(s): Salmonella and Campylobacter epidemiology
2017 - Elsevier BV | Diagnostic Microbiology and Infectious Disease

Marcela Marta Lazaretti Tormena, Luana Tabalipa de Medeiros, Patrícia Casarin de Lima, Gabriela Possebon, Renata Hernandez Barros Fuchs, Evandro Bona,
In this study, a chocolate cake formulation was developed with partial substitution of wheat flour by yacon and maca flour. A simplex-centroid design was applied to determine the proportions of the three flours, and the amount of water was included as a process variable at three distinct levels. According to the overall acceptability of the cakes, the tasters were separated into two groups using k-means.After segmentation, regression models were constructed for overall acceptability of each group; ...
Tópico(s): Seed and Plant Biochemistry
2017 - Wiley | Journal of the Science of Food and Agriculture

Marcela Moreira Albuquerque, Walter José Martínez-Burgos, Gabriela de Bona Sartor, Luiz Alberto Júnior Letti, Júlio César de Carvalho, Carlos Ricardo Soccol, Adriane Bianchi Pedroni Medeiros,
Palm oil, the main vegetable oil produced globally, serves diverse purposes, ranging from cooking to the production of processed foods, cosmetics, and biodiesel. Despite contributing significantly to the economies of major producing nations, the escalating production of palm oil raises serious environmental concerns, including deforestation, biodiversity loss, and various forms of pollution. Palm oil mill effluent (POME), a byproduct of palm oil extraction, poses a severe environmental threat when ...
Tópico(s): Hybrid Renewable Energy Systems
2024 - Multidisciplinary Digital Publishing Institute | Fermentation

J. Límaco, H. R. Clark, L. A. Medeiros,
We investigate an initial-boundary value problem for equations of Benjamin–Bona–Mahony (BBM) type in two different physical situations. In the first, the mixed problem is considered on a cylinder domain Q of Rn×Rt. In the second one, the mixed problem is studied inside of an increasing noncylindrical domain Qˆ of Rn×Rt. In both situations we show the existence of a unique nonlocal solution. In cylindrical case it is proved the existence of weak and strong solutions, regularity of strong solutions, ...
Tópico(s): Advanced Mathematical Modeling in Engineering
2006 - Elsevier BV | Journal of Mathematical Analysis and Applications

Luiza Pelinson Tridapalli, Flávia Aparecida Reitz Cardoso, Lucas Shinti Iwamura, Adriana Aparecida Droval, Leila Larisa Medeiros Marques, Evandro Bona, Stéphani Caroline Beneti, Stênio Cristaldo Heck, Renata Hernandez Barros Fuchs,
Summary Replacing gluten‐containing flours with gluten‐free ingredients is a challenge for the food industry due to the technological properties of this protein. This work aimed to evaluate, through the acceptance test, Flash Profile, and Just About Right (JAR), gluten‐free bread formulations made with sorghum, teff, and yacon flours. Through experimental design, nine formulations were submitted to acceptance test, which provided the formulation optimised by the overall acceptance scores of the samples. ...
Tópico(s): Celiac Disease Research and Management
2023 - Wiley | International Journal of Food Science & Technology

José Gilberto Sousa Medeiros, Luiz Antônio Biasi, Claudine Maria de Bona, Francine Lorena Cuquel,
Abstract Studies on adaptation to the cultivation site are necessary for the recommendation of new cultivars. The aim of this study was to evaluate the phenological development, productivity and fruit quality of eight blueberry cultivars from the rabbiteye group (Aliceblue, Bluebelle, Bluegem, Briteblue, Climax, Delite, Powderblue and Woodard) and two from the highbush group (Georgiagem and O’Neal) under humid subtropical conditions in the 2012/2013, 2013/2014 and 2014/2015 cycles. Beginning and end ...
Tópico(s): Horticultural and Viticultural Research
2018 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
Bruno C. Medeiros, William N. Rezuke, Andrew Ricci, Gregory J. Tsongalis, Peter U.F. Shen, Robert Bona, Jay Feingold, R. Lawrence Edwards, P. J. Tutschka, S Bilgrami,
Unlike solid organ transplantation, Kaposi’s sarcoma (KS) occurs rarely following hematopoietic stem cell transplantation (HSCT). In fact, only 5 cases of KS have been reported after allogeneic or autologous HSCT. The usual treatment combines a substantial decrease in, or elimination of, immunosuppressive therapy along with local measures such as surgical excision, cryotherapy or radiation therapy. A 46-year-old woman with chronic myelogenous leukemia who had received an allogeneic HSCT previously ...
Tópico(s): Lymphoma Diagnosis and Treatment
2000 - Karger Publishers | Acta Haematologica

Marcela Moreira Albuquerque, Gabriela de Bona Sartor, Walter José Martínez-Burgos, Thamarys Scapini, Thiago Edwiges, Carlos Ricardo Soccol, Adriane Bianchi Pedroni Medeiros,
Hydrogen (H2) is a highly efficient and clean energy source with the potential for renewable energy. The production of H2 from biological routes such as biophotolysis, photofermentation, dark fermentation, and bioelectrochemical production is characterized as a renewable alternative to current production, which is mainly based on energy-intensive electrochemical and thermochemical processes and responsible for the emission of high amounts of environmentally harmful compounds. Dark fermentation is ...
Tópico(s): Hydrogen Storage and Materials
2024 - Multidisciplinary Digital Publishing Institute | Methane

Éder Ricardo Petry, Diego de Freitas Dresch, Clarice Carvalho, Patricia Calçada Medeiros, Tatiana Gomes Rosa, Cleverson Moraes de Oliveira, Léo Anderson Meira Martins, Elizângela Gonçalves Schemitt, Sílvia Bona, Fátima Theresinha Costa Rodrigues Guma, Norma Possa Marroni, Clóvis Milton Duval Wannmacher,
Skeletal muscle disuse results in myofibrillar atrophy and protein degradation, via inflammatory and oxidative stress-mediated NF-kB signaling pathway activation. Nutritional interventions, such as l-glutamine (GLN) supplementation have shown antioxidant properties and cytoprotective effects through the modulation on the 70-kDa heat shock protein (HSP70) expression. However, these GLN-mediated effects on cell signaling pathways and biochemical mechanisms that control the myofibrillar protein content ...
Tópico(s): Adipose Tissue and Metabolism
2019 - Elsevier BV | Free Radical Biology and Medicine

Juliana Arisi Medeiros, Óscar E. Pecho, María del Mar Pérez Gómez, Francisco Carrillo‐Pérez, Luis Javier Herrera, Álvaro Della Bona,
To evaluate the influence of neutral color backgrounds on the perception of color differences in dentistry.A software was developed for this study that calculated the perceptibility (PT) and acceptability (AT) thresholds of color differences between a pair of computer-simulated incisor samples (n = 60 pairs) over three neutral color (white, gray and black) backgrounds. CIELAB and CIEDE2000 color difference formulas were used. Five groups of volunteer observers (N = 100) participated in the psychophysical ...
Tópico(s): Color Science and Applications
2021 - Elsevier BV | Journal of Dentistry

Veruschka Rocha Medeiros Andreolla, Aníbal de Moraes, Amadeu Bona Filho, Décio Lopes Cardoso, E. B. de Oliveira, Andréia Kusumota Bonini,
RESUMO O sistema de integração lavoura-pecuária (SILP) é uma alternativa que vem atraindo grande interesse dos agricultores nas regiões produtoras de grãos, devido ao suporte à pecuária por meio da produção de alimento, além de melhoria nas propriedades físicas do solo. O objetivo deste trabalho foi avaliar o efeito do pastejo e da adubação nitrogenada em atributos físicos do solo e na produtividade da cultura do milho, em um sistema de integração lavoura-pecuária. O delineamento foi em blocos ao ...
Tópico(s): Growth and nutrition in plants
2015 - Sociedade Brasileira de Engenharia Agrícola | Engenharia Agrícola

Aldo Â. M. Lima, Domingos B. Oliveira, Josiane da Silva Quetz, Alexandre Havt, Mara de Moura Gondim Prata, Ila F.N. Lima, Alberto M. Soares, José Q. Filho, Noélia L. Lima, Pedro Henrique Quintela Soares de Medeiros, Ana Karolina Silva dos Santos, Herlice N. Veras, Rafhaella N. D. G. Gondim, Rafaela C. Pankov, Mariana Duarte Bona, F.A.P. Rodrigues, Renato de Azevedo Moreira, Ana C. O. M. Moreira, M. Bertolini, Luciana Relly Bertolini, Vicente José de Figueirêdo Freitas, Eric R. Houpt, Richard L. Guerrant,
Background Diarrheal diseases are an important cause of morbidity and mortality among children in developing countries. We aimed to study the etiology and severity of diarrhea in children living in the low-income semiarid region of Brazil. Methodology This is a cross-sectional, age-matched case-control study of diarrhea in children aged 2–36 months from six cities in Brazil's semiarid region. Clinical, epidemiological, and anthropometric data were matched with fecal samples collected for the identification ...
Tópico(s): Congenital Anomalies and Fetal Surgery
2019 - Public Library of Science | PLoS neglected tropical diseases

Herlice do Nascimento Veras, Pedro Henrique Quintela Soares de Medeiros, Samilly Albuquerque Ribeiro, Thiago M. Freitas, Ana Karolina Silva dos Santos, M.S.M.G. Amaral, Mariana Duarte Bona, Alexandre Havt, Ila F.N. Lima, Noélia L. Lima, Alessandra Di Moura, Álvaro M. Leite, Alberto M. Soares, José Q. Filho, Richard L. Guerrant, Aldo Â. M. Lima,
Tópico(s): Trace Elements in Health
2018 - Springer Science+Business Media | European Journal of Clinical Microbiology & Infectious Diseases

Lucas de Souza Nespeca, Flávia Aparecida Reitz Cardoso, Adriana Aparecida Droval, Leila Larisa Medeiros Marques, Evandro Bona, Stéphani Caroline Beneti, Stênio Cristaldo Heck, Renata Hernandez Barros Fuchs,
Summary This study aimed to optimise an orange flavour gluten‐free cake formulation using rice flour, teff, sorghum and yacon. Nine cake formulations were initially submitted for acceptance and purchase intent tests with 66 assessors, where colour, odour, flavour, texture and overall acceptance were judged. After the result of the acceptance test and purchase intention, an optimised formulation (OP) was elaborated through the desirability function. This formulation was composed of 25% rice flour, ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2023 - Wiley | International Journal of Food Science & Technology