Sébastien Bridel, Valérie Bouchez, Bryan Brancotte, Sofia Hauck, Nathalie Armatys, Annie Landier, Estelle Mühle, Sophie Guillot, Julie Toubiana, Martin Maiden, Keith A. Jolley, Sylvain Brisse,
Abstract The genus Bordetella includes bacteria that are found in the environment and/or associated with humans and other animals. A few closely related species, including Bordetella pertussis , are human pathogens that cause diseases such ... cough. Here, we present a large database of Bordetella isolates and genomes and develop genotyping systems for ... bronchiseptica genomes. The public database currently includes 2582 Bordetella isolates and their provenance data, and 2085 genomes ( https://bigsdb.pasteur.fr/bordetella/ ). We use core-genome multilocus sequence typing (cgMLST) ...
Tópico(s): Genomics and Phylogenetic Studies
2022 - Nature Portfolio | Nature Communications
Ivana Malcová, Ladislav Bumba, Filip Uljanic, Darya Kuzmenko, Jana Nedomova, Jana Kamanová,
The respiratory pathogens Bordetella pertussis and Bordetella bronchiseptica employ a type III secretion system (T3SS) to inject a 69-kDa BteA effector protein into host cells. This effector is ... as its cytotoxic activity in the course of Bordetella infections remain poorly understood. Using a protein–lipid ... therefore, dispensable for effector cytotoxicity. The respiratory pathogens Bordetella pertussis and Bordetella bronchiseptica employ a type III secretion system (T3SS) ... as its cytotoxic activity in the course of Bordetella infections remain poorly understood. Using a protein–lipid ...
Tópico(s): Escherichia coli research studies
2021 - Elsevier BV | Journal of Biological Chemistry
Gianmarco Gasperini, Massimiliano Biagini, Vanessa Arato, Claudia Gianfaldoni, Alessandro Vadi, Nathalie Norais, G. Bensi, Isabel Delany, Mariagrazia Pizza, Beatrice Aricò, Rosanna Leuzzi,
... whooping cough, a highly contagious disease caused by Bordetella pertussis, is recently increasing in occurrence suggesting that ... whooping cough, a highly contagious disease caused by Bordetella pertussis, is recently increasing in occurrence suggesting that ... the impact of vaccination on the bacterial clearance. Bordetella pertussis is a Gram-negative bacterium, obligate human ... E.V. Miller J.F. Cotter P.A. Bordetella pertussis pathogenesis: current and future challenges.Nat. Rev. ... Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2017 - Elsevier BV | Molecular & Cellular Proteomics
Illiassou Hamidou Soumana, Bodo Linz, Eric T. Harvill,
Members of the genus Bordetella include human and animal pathogens that cause a variety of respiratory infections, including whooping cough in humans. Despite the long ... growth conditions, no extra-host niches of pathogenic Bordetella species have been defined. To better understand the distribution of Bordetella species in the environment, we probed the NCBI ... ribosomal RNA (16S rRNA) gene sequences from pathogenic Bordetella species. Bacteria of the genus Bordetella were frequently found in soil, water, sediment, and ...
Tópico(s): Genomics and Phylogenetic Studies
2017 - Frontiers Media | Frontiers in Microbiology
Erich V. Scheller, Jeffrey A. Melvin, Amanda Sheets, Peggy A. Cotter,
ABSTRACT Bordetella fimbriae (FIM) are generally considered to function as adhesins despite a lack of experimental evidence supporting this conclusion for Bordetella pertussis and evidence against a requirement for FIM in adherence of Bordetella bronchiseptica to mammalian cell lines. Using B. bronchiseptica ... airway epithelium is a critical first step in Bordetella infection that allows FHA-dependent interactions to mediate ... surprisingly little experimental evidence supporting this role for Bordetella fimbria. Our results provide the first demonstration that ...
Tópico(s): Virology and Viral Diseases
2015 - American Society for Microbiology | mBio
Peter Vandamme, Charlotte Peeters, Margo Cnockaert, Elisabeth Inganäs, Enevold Falsen, Edward R. B. Moore, Olga C. Nunes, Célia M. Manaia, Theodore Spilker, John J. LiPuma,
The phenotypic and genotypic characteristics of four Bordetella hinzii-like strains from human respiratory specimens and representing nrdA gene sequence based genogroups 3, 14 and 15 were examined. In a 16S ... coherent lineage but their assignment to the genus Bordetella was equivocal. The respiratory quinone, polar lipid and ... conformed to those of species of the genus Bordetella and were characterized by the presence of ubiquinone ... genera of the family Alcaligenaceae including the genus Bordetella. DNA–DNA hybridization experiments revealed the presence of ...
Tópico(s): Actinomycetales infections and treatment
2015 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
Kevin B. Spicer, Doug Salamon, Carol O. Cummins, Amy L. Leber, Loren Rodgers, Mario J. Marcon,
... insertion sequence IS481, which is found in both Bordetella pertussis (Bp) and Bordetella holmesii (Bh). An increase in specimens testing positive for Bordetella parapertussis (Bpp) using insertion sequence IS1001 was also ... A subgroup of specimens was also cultured for Bordetella species, and antimicrobial susceptibility testing was performed on ... positive for Bpp, Bp and Bh, respectively. All Bordetella species were susceptible to macrolide antibiotics. Patients with ... 24 Bh, 80 Bpp and 100 negative for Bordetella species), but did not differ statistically among the ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2014 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
А. В. Новиков, Nita R. Shah, Sami Albitar‐Nehme, Soorej M. Basheer, Ilaria Trento, Alina Tîrşoaga, Michelle Moksa, Martin Hirst, Malcolm B. Perry, Asmaa El Hamidi, Rachel C. Fernandez, Martine Caroff,
... as one of the virulence factors of the Bordetella avium bird pathogen, and characterization of its structure ... pathogenicity and for an improved general knowledge of Bordetella spp virulence factors. The structure of the biologically ... those of another bird pathogen, opportunistic in humans, Bordetella hinzii, and to that of Bordetella trematum, a human pathogen. Sequence analyses showed that ... were similar, but they differed from those of Bordetella pertussis and Bordetella parapertussis. They were also found ...
Tópico(s): RNA and protein synthesis mechanisms
2013 - SAGE Publishing | Innate Immunity
Nicolas Hégerlé, Lamya Rayat, Gregory J. Dore, Nora Zidane, Hugues Bedouelle, Nicole Guiso,
Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica are three closely related pathogens. They all possess the gene coding for the Bordetella type three secretion system effector A (bteA) toxin ...
Tópico(s): Vector-borne infectious diseases
2013 - Elsevier BV | Microbes and Infection
David Hot, Stéphanie Slupek, Bérénice Wulbrecht, Anthony D'Hondt, Christine Hubans, Rudy Antoine, Camille Locht, Yves Lemoine,
... So far, little is known about sRNAs in Bordetella, and only very few sRNAs have been identified in the genome of Bordetella pertussis, the causative agent of whooping cough.An ... pertussis genome. The genome sequences of B. pertussis, Bordetella parapertussis, Bordetella bronchiseptica and Bordetella avium were compared using a Blast, and significant ... 20 additional candidates. These new sRNAs were named Bordetella pertussis RNAs, bpr. The expression of 4 of ... of BvgA/BvgS two-component regulatory system of Bordetella virulence. A phylogenetic study of the bprJ sequence ...
Tópico(s): RNA and protein synthesis mechanisms
2011 - BioMed Central | BMC Genomics
Aukje C. Bos, Petra M. M. Beemsterboer, Tom F.W. Wolfs, F. G. A. Versteegh, Hubertus G.M. Arets,
... verify what is known about the role of Bordetella species in children with cystic fibrosis, with regard to the incidence of Bordetella infections, the involvement in pulmonary exacerbations and the ... course.Little is known about the frequency of Bordetella infections and the involvement of Bordetella species both in relation to the chronic course ... pulmonary exacerbations. Since it is difficult to detect Bordetella species in cultures and few sputum cultures investigated ... exacerbation, it is likely that the frequency of Bordetella species in CF patients is underestimated. Identification of ...
Tópico(s): Pneumonia and Respiratory Infections
2011 - Elsevier BV | Journal of Cystic Fibrosis
Silvia Rossi Paccani, Marisa Benagiano, Maria Teresa Savino, Francesca Finetti, Fiorella Tonello, Mario Milco D’Elios, Cosima T. Baldari,
... The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T ... The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T ... The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T ... The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T ... The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2011 - Elsevier BV | Journal of Allergy and Clinical Immunology
B. Éliás, Monika Krüger, F. Rátz,
... Schweines: II. Biologische Eigenschaften der von Schweinen isolierten Bordetella bronchiseptica-Stämme Dr. B. ÉLiás, Corresponding Author Dr. ... Die Autoren haben die biologischen Eigenschaften von 12 Bordetella bronchiseptica-Stämmen vom Schwein aus Beständen mit schwerem, ... atrophic rhinitis of swine II. Biological characters of Bordetella bronchiseptica strains isolated from pigs Twelve strains of Bordetella bronchiseptica isolated from pigs from herds with severe, ... du porc II. Propriétés biologiques de souches de Bordetella bronchiseptica isolées chez des porcs Les propriétés biologiques ...
Tópico(s): Bacterial Infections and Vaccines
2010 - Wiley | Zentralblatt für Veterinärmedizin Reihe B
Evgeny Vinogradov, Jerry D. King, Ashutosh K. Pathak, Eric T. Harvill, Andrew Preston,
The O chain polysaccharide (O PS) of Bordetella bronchiseptica and Bordetella parapertussis lipopolysaccharide is a homopolymer of 2,3-diacetamido-2,3-dideoxygalacturonic acid (GalNAc3NAcA) in which some of the sugars ... reactivity between the two types. This suggests that Bordetella O PS modifications represent a means of antigenic ... biosynthesis) locus. Thus, there is greater diversity among Bordetella O PSs than previously recognized, which is likely ... configuration of the diacetimido-uronic acid sugars in Bordetella O PS. The O chain polysaccharide (O PS) ...
Tópico(s): Pneumonia and Respiratory Infections
2010 - Elsevier BV | Journal of Biological Chemistry
K.‐H. Hinz, G Glünder, B. Stiburek, H Lüders,
... biochemischer Untersuchungen von 7 Bakterien-Stämmen der Gattung Bordetella, von denen 5 aus der Pute und je ... waren die Eigenschaften der Feldstämme denen der Species Bordetella bronchiseptica sehr ähnlich. Experimentell konnte nachgewiesen werden, daß ... thermostabilen somatischen Antigen der Puten-Bordetellen und eines Bordetella bronchiseptica-Stammes aus dem Schwein sprechen für die ... biochemical investigations of 7 strains of the species Bordetella, of which 5 had been isolated from the ... strains are similar to those of the species Bordetella bronchiseptica with the exception of their weak positive ...
Tópico(s): Bird parasitology and diseases
2010 - Wiley | Zentralblatt für Veterinärmedizin Reihe B
Theodore Spilker, A.A. Liwienski, John J. LiPuma,
Abstract Bordetella spp. are not normally included when considering the opportunistic bacterial species that are typically involved in respiratory ... combination of bacterial genotyping and 16S rDNA sequencing, Bordetella spp. were identified in cultures obtained from 43 ... CF. Most ( n = 23) patients were infected with Bordetella bronchiseptica / parapertussis ; five were infected with Bordetella hinzii , four with Bordetella petrii , three with Bordetella avium , and eight with unidentified Bordetella spp. Consideration ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2008 - Elsevier BV | Clinical Microbiology and Infection
Jeroen Geurtsen, Eline Angevaare, Marlieke Janssen, Hendrik-Jan Hamstra, Jan ten Hove, Alex de Haan, Betsy Kuipers, Jan Tommassen, Peter van der Ley,
... of two lpxL homologues in the genome of Bordetella pertussis. We show that one of them, LpxL2, ... of two lpxL homologues in the genome of Bordetella pertussis. We show that one of them, LpxL2, ... Pertussis is caused by the Gram-negative bacterium Bordetella pertussis. While the genus Bordetella currently encompasses nine species, apart from B. pertussis only three other members, Bordetella bronchiseptica, Bordetella parapertussis, and Bordetella holmesii, have been associated with respiratory infections in ...
Tópico(s): Salmonella and Campylobacter epidemiology
2007 - Elsevier BV | Journal of Biological Chemistry
Alina Tîrşoaga, Asmaa El Hamidi, Malcolm B. Perry, Martine Caroff, А. В. Новиков,
... other hand, when applied to two batches of Bordetella bronchiseptica strain 4650, it highlighted the presence, in ... other hand, when applied to two batches of Bordetella bronchiseptica strain 4650, it highlighted the presence, in ... Harvill E.T. Caroff M. Maskell D.J. Bordetella bronchiseptica PagP is a Bvg-regulated lipid A ... in the "isolated lipid A" fragment of the Bordetella pertussis endotoxin.Carbohydr. Res. 1988; 175: 273-282Crossref ... many lipid A preparations, such as those of Bordetella (12.Caroff M. Brisson J.R. Martin A. ...
Tópico(s): Salmonella and Campylobacter epidemiology
2007 - Elsevier BV | Journal of Lipid Research
Jan Bonhoeffer, Gayathri BR, Marion Riffelmann, M Solr, Ulrich Heininger,
... some of which are potentially preventable by immunization. Bordetella pertussis, which causes whooping cough, has not been ... context. We aimed to assess the role of Bordetella infections in patients with AECB.Patients with AECB, ... by a standardized questionnaire, nasopharyngeal swabs for culture (Bordetella spp.), and PCR (Bordetella spp. and selected other respiratory pathogens) and paired blood samples for serologic diagnosis of Bordetella infection.A total of 26 patients (34-86 ... culture and PCR samples were negative. Serology revealed Bordetella infection in eight (31%) patients. Duration of cough ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2005 - Springer Science+Business Media | Infection
Asmaa El Hamidi, Alina Tîrşoaga, А. В. Новиков, Ahmed Hussein, Martine Caroff,
... in the “isolated lipid A” fragment of the Bordetella pertussis endotoxin.Carbohydr. Res. 1988; 175: 273-282Google ... strain b Eagan) and the smooth-type bacteria Bordetella holmesii (ATCC 51541), both from National Research Council ( ... Biochimie, Biophysique Moléculaire et Cellulaire (Orsay, France), and Bordetella pertussis (strain Bp1414) from the Institut Mérieux (Lyon, ... in the “isolated lipid A” fragment of the Bordetella pertussis endotoxin.Carbohydr. Res. 1988; 175: 273-282Google ... in the “isolated lipid A” fragment of the Bordetella pertussis endotoxin.Carbohydr. Res. 1988; 175: 273-282Google ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2005 - Elsevier BV | Journal of Lipid Research
Gabriele Gerlach, Simone Janzen, Dagmar Beier, Roy Gross,
... of virulence gene expression in the mammalian pathogens Bordetella pertussis , Bordetella parapertussis and Bordetella bronchiseptica . This paper reports the partial cloning and characterization of the bvgAS loci of the ‘new’ Bordetella species Bordetella holmesii , Bordetella trematum and Bordetella hinzii , which are increasingly recognized as opportunistic pathogens ...
Tópico(s): Genomics and Phylogenetic Studies
2004 - Microbiology Society | Microbiology
Trevor P. Anderson, K.A. Beynon and, David R. Murdoch,
... time (LightCycler) PCR assay for the detection of Bordetella pertussis in nasopharyngeal samples. Of the 152 samples ... time (LightCycler) PCR assay for the detection of Bordetella pertussis in nasopharyngeal samples. Of the 152 samples ... highly communicable, vaccine-preventable respiratory disease caused by Bordetella pertussis and, occasionally, other Bordetella species [1Yih WK Silva EA Ida J Harrington N Lett SM George H Bordetella holmesii-like organisms isolated from Massachusetts patients with ... Mukkur TKS Rapid-cycle PCR method to detect Bordetella pertussis that fulfills all consensus recommendations for use ...
Tópico(s): Rabies epidemiology and control
2003 - Elsevier BV | Clinical Microbiology and Infection
Ignacio Gadea, Manuel Cuenca‐Estrella, Natividad Benito, A. Blanco, Manuel L. Fernández-Guerrero, Pedro L. Valero-Guillén, Francisco García Soriano,
Most clinicians and microbiologists are familiar with Bordetella pertussis, its associated clinical syndromes and treatment with antimicrobials, and both biochemical and molecular methods for identification. Many of the other Bordetella species are much less well known, though they do cause clinical disease in humans. Some, like Bordetella parapertussis and Bordetella holmesii, are common causes of respiratory disease (albeit ... individuals with no significant comorbidities; others, such as Bordetella trematum and Bordetella ansorpii, have been noted to ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2000 - Elsevier BV | Journal of Infection
Caroline Boursaux‐Eude, Nicole Guiso,
... Pertactin is an outer membrane protein expressed by Bordetella pertussis , Bordetella parapertussis , and Bordetella bronchiseptica that induces protective immunity to Bordetella infections. The immunodominant and immunoprotective epitopes of pertactin ... differences may result from specific characteristics of these Bordetella species.
Tópico(s): Escherichia coli research studies
2000 - American Society for Microbiology | Infection and Immunity
Susan Dawson, Dan Christopher Jones, Christina McCracken, R. M. Gaskell, C. A. Hart, C. J. Gaskell,
... 146, Issue 2 p. 46-48 Short Communication Bordetella bronchiseptica infection in cats following contact with infected ... M. (1999) Prevalence and risk factors for feline Bordetella bronchiseptica infection. Veterinary Record 144, 575–580 BINNS, ... field gel electophoresis to examine the epidemiology of Bordetella bronchiseptica isolated from cats and other species. Epidemiology ... R. M. (1996) Studies on natural transmission of Bordetella bronchiseptica in cats. Veterinary Microbiology 48, 19–27 CROSS, R. F. & CAFLIN, R. M. (1962) Bordetella bronchiseptica-induced porcine atrophic rhinitis. Journal of the ...
Tópico(s): Rabies epidemiology and control
2000 - Wiley | Veterinary Record
Rose‐Marie Carlsson, Bo A. Claesson, Teresa Lagergård, Birger Trollfors,
... Pertussis toxin (PT) is an extracellular toxin of Bordetella pertussis, while FHA and pertactin are immunogenic surface ... antibodies related to protection after household exposure to Bordetella pertussis.Vaccine. 1998; 16: 1907-1916Crossref PubMed Scopus ( ... regions of the P.69 protein, pertactin. from Bordetella pertussis: comparison with repeat sequences from Bordetella parapertussis and Bordetella broncliiseptica.in: Manclark CR Proceedings of the Sixth ... Smith P Heterogeneity of the filamentous hemagglutinin of Bordetella pertussis studied with monoclonal antibodies.J Gen Microbiol. ...
Tópico(s): Infective Endocarditis Diagnosis and Management
1999 - Elsevier BV | Clinical Microbiology and Infection
Johnny D. Hoskins, Jennifer L. Williams, Alma Roy, J.C. Peters, Patrick L. McDonough,
The role of Bordetella bronchiseptica in respiratory disease of domestic cats is currently being explored. Clinical and experimental studies in the United Kingdom have shown Bordetella bronchiseptica to be a primary respiratory pathogen in ... on the isolation, seroprevalence, and partial characterization of Bordetella bronchiseptica from shelter cats in southern Louisiana. A ... to be asymptomatic for signs of respiratory disease. Bordetella bronchiseptica was isolated in 19/614 (3.1%) ... 148/614 (24.1%) cats were seropositive for Bordetella bronchiseptica. The 25 isolates of Bordetella bronchiseptica were ...
Tópico(s): Vector-borne infectious diseases
1998 - Elsevier BV | Veterinary Immunology and Immunopathology
... pathogenicity: environmental effects on virulence gene expression in Bordetella pertussis. Journal of General Microbiology 137, 2493–2503. ... A., Falkow, S. and Cowell, J.L. (1990) Bordetella pertussis filamentous haemagglutinin: evaluation as a protective antigen ... J. (1991) Pertactin, an arg-gly-asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian ... R. and Falkow, S. (1989) Filamentous haemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. ...
Tópico(s): Microbial infections and disease research
1993 - Wiley | Journal of Applied Bacteriology
Mitsuru Watanabe, Yasukiyo Nakase, Tatsuo Aoyama, Hiroko Ozawa, Yuji Murase, Takashi Iwata,
... Original ArticleFree Access Serotype and Drug Susceptibility of Bordetella pertussis Isolated in Japan from 1975 to 1984 ... M., and Cheung, R. 1982. Antimicrobial susceptibility of Bordetella pertussis strains isolated from 1960 to 1981. Antimicrob. ... R.M., and Cheung, R. 1984. Susceptibility of Bordetella pertussis to cephalosporin derivatives and imipenem. Antimicrob. Agents ... and Fulton, L.C. 1971. The occurrence of Bordetella pertussis serotypes in Australia, 1950–1970. Med. J. ... Standfast, A.F.B. 1976. The serotypes of Bordetella pertussis isolated in Great Britain between 1941 and ...
Tópico(s): Infective Endocarditis Diagnosis and Management
1986 - Wiley | Microbiology and Immunology
Zusammenfassung Vergleichende Prüfungen auf Toxinbildung von Bordetella‐bronchiseptica‐ und Pasteurella‐multocida‐Stämmen aus 2 Ra‐freien und 12 Ra‐positiven Beständen mit unter‐schiedlicher Ra‐Morbiditat ergaben folgende Hinweise: — ... atrophic rhinitis Comparative studies on toxin production of Bordetella bronchiseptica and Pasteurella multocida strains from two AR‐ ... with varying AR‐morbidity gave the following results: — Bordetella strains with marked or medium toxin production were ... toxin which apparently had the same effect as Bordetella exotoxin and belonged mainly to Cardet D‐, but ...
Tópico(s): Bacterial Infections and Vaccines
1985 - Wiley | Zentralblatt für Veterinärmedizin Reihe B