Marie Sofie Møller, Souad El Bouaballati, Bernard Henrissat, Birte Svensson,
... 21Pires V.M.R. Pereira P.M.M. Brás J.L.A. Correia M. Cardoso V. Bule P. Alves V.D. Najmudin S. ... 21Pires V.M.R. Pereira P.M.M. Brás J.L.A. Correia M. Cardoso V. Bule P. Alves V.D. Najmudin S. ...
Tópico(s): Polysaccharides and Plant Cell Walls
2021 - Elsevier BV | Journal of Biological Chemistry
Produção Nacional
Revisado por pares
M.V. Liberato, Bruna Campos, Geizecler Tomazetto, Lucy I. Crouch, Wanius García, Ana Carolina de Mattos Zeri, David N. Bolam, Fábio M. Squina,
... 33Pires V.M.R. Pereira P.M.M. Brás J.L.A. Correia M. Cardoso V. Bule P. Alves V.D. Najmudin S. ...
Tópico(s): Polysaccharides Composition and Applications
2022 - Elsevier BV | Journal of Biological Chemistry
Virgínia M. R. Pires, Pedro M. Pereira, Joana L. A. Brás, M.A.S. Correia, Vânia Cardoso, Pedro Bule, Victor D. Alves, Shabir Najmudin, I. Venditto, L.M.A. Ferreira, Maria João Romão, Ana Luı́sa Carvalho, C.M.G.A. Fontes, D.M.F. Prazeres,
Deconstruction of cellulose, the most abundant plant cell wall polysaccharide, requires the cooperative activity of a large repertoire of microbial enzymes. Modular cellulases contain non-catalytic type A carbohydrate-binding modules (CBMs) that specifically bind to the crystalline regions of cellulose, thus promoting enzyme efficacy through proximity and targeting effects. Although type A CBMs play a critical role in cellulose recycling, their mechanism of action remains poorly understood. Here ...
Tópico(s): Enzyme Production and Characterization
2017 - Elsevier BV | Journal of Biological Chemistry
Susana Brás, Pedro Mendes‐Bastos, Cristina Amaro, Jorge Cardoso,
... for more papers by this authorJorge Cardoso, Jorge Cardoso Department of Dermatology and Venereology, Hospital de Curry Cabral – Centro Hospitalar de Lisboa Central, 1069-166 Lisboa, PortugalSearch for more papers by this author Susana Brás, Corresponding Author Susana Brás Department of Dermatology and ...
Tópico(s): Food Allergy and Anaphylaxis Research
2015 - Wiley | Contact Dermatitis
Produção Nacional
Revisado por pares
... its importance' (Santos 2001, 145). 3. Especially Mathias Cardoso, Antônio Gonçalves, Brás Esteves Leme (1715), and the brothers Domingos and ...
Tópico(s): History of Colonial Brazil
2012 - Routledge | Colonial Latin American Review
Sun Li Chong, Vânia Cardoso, Joana L. A. Brás, Milene Zezzi do Valle Gomes, C.M.G.A. Fontes, Lisbeth Olsson,
Here, we demonstrated the immobilization of bacterial feruloyl esterase (FAE) from Butyrivibrio sp. XPD2006, Lactobacillus crispatus, Butyrivibrio sp. AE2015, Ruminococcus albus, Cellulosilyticum ruminicola and Clostridium cellulovorans on SBA-15 and their ability to synthesize butyl ferulate (BFA). The BFae2 from Butyrivibrio sp. XPD2006 showed the best catalytic efficiency. High BFA yield was produced when the immobilization of BFae2 took place with a high protein loading and narrow pore sized SBA- ...
Tópico(s): Enzyme Production and Characterization
2019 - Elsevier BV | Bioresource Technology
Pedro Mendes‐Bastos, Susana Brás, Cristina Amaro, Jorge Cardoso,
... for more papers by this authorSusana Brás, Susana Brás Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorCristina Amaro, Cristina Amaro Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorJorge Cardoso, Jorge Cardoso Dermatology and Venereology Department, Hospital de ... for more papers by this authorSusana Brás, Susana Brás Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorCristina Amaro, Cristina Amaro Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorJorge Cardoso, Jorge Cardoso Dermatology and Venereology Department, Hospital de ...
Tópico(s): Food Allergy and Anaphylaxis Research
2014 - Wiley | JDDG Journal der Deutschen Dermatologischen Gesellschaft
Ana R. Brás, João Paulo Noronha, Alexandra M. M. Antunes, M. Margarida Cardoso, Andreas Schönhals, Frédéric Affouard, Madalena Dionı́sio, Natália T. Correia,
The molecular mobility of amorphous ibuprofen has been investigated by broadband dielectric relaxation spectroscopy (DRS) covering a temperature range of more than 200 K. Four different relaxation processes, labeled as alpha, beta, gamma, and D, were detected and characterized, and a complete relaxation map was given for the first time. The gamma-process has activation energy E a = 31 kJ.mol (-1), typical for local mobility. The weak beta-relaxation, observed in the glassy state as well as in the supercooled ...
Tópico(s): Glass properties and applications
2008 - American Chemical Society | The Journal of Physical Chemistry B
Chris Lane, Thomas D. Parker, David M. Cash, Kirsty Macpherson, Elizabeth Donnachie, Heidi Murray‐Smith, Anna Barnes, Suzie Barker, Daniel Beasley, José Brás, David A. Brown, Ninon Burgos, Michelle Byford, M. Jorge Cardoso, Ana C. Carvalho, Jessica Collins, Enrico De Vita, John Dickson, Norah Epie, Miklos Espak, Susie M.D. Henley, Chandrashekar Hoskote, Michael Hütel, Jana Klímová, Ian B. Malone, Paweł Markiewicz, Andrew Melbourne, Marc Modat, Anette Schrag, Sachit Shah, Nikhil Sharma, Carole H. Sudre, David L. Thomas, Andrew Wong, Hui Zhang, John Hardy, Henrik Zetterberg, Sébastien Ourselin, Sebastian J. Crutch, Diana Kuh, Marcus Richards, Nick C. Fox, Jonathan M. Schott,
Increasing age is the biggest risk factor for dementia, of which Alzheimer’s disease is the commonest cause. The pathological changes underpinning Alzheimer’s disease are thought to develop at least a decade prior to the onset of symptoms. Molecular positron emission tomography and multi-modal magnetic resonance imaging allow key pathological processes underpinning cognitive impairment – including β-amyloid depostion, vascular disease, network breakdown and atrophy – to be assessed repeatedly and non- ...
Tópico(s): Functional Brain Connectivity Studies
2017 - BioMed Central | BMC Neurology
Sandra Tavares, André Filipe Vieira, Anna Taubenberger, Margarida Araújo, Nuno Pimpão Martins, Catarina Brás‐Pereira, António Polónia, Maik Herbig, Clara Barreto, Oliver Otto, Joana Cardoso, José B. Pereira‐Leal, Jochen Guck, Joana Paredes, Florence Janody,
Abstract Studies of the role of actin in tumour progression have highlighted its key contribution in cell softening associated with cell invasion. Here, using a human breast cell line with conditional Src induction, we demonstrate that cells undergo a stiffening state prior to acquiring malignant features. This state is characterized by the transient accumulation of stress fibres and upregulation of Ena/VASP-like (EVL). EVL, in turn, organizes stress fibres leading to transient cell stiffening, ERK- ...
Tópico(s): Hippo pathway signaling and YAP/TAZ
2017 - Nature Portfolio | Nature Communications
Produção Nacional
Revisado por pares
Sarah Camargos, Sonja W. Scholz, Javier Simón‐Sánchez, Coro Paisàn‐Ruìz, Patrick A. Lewis, Dena G. Hernandez, Jinhui Ding, J. Raphael Gibbs, Mark Cookson, José Brás, Rita Guerreiro, Catarina R. Oliveira, Andrew J. Lees, John Hardy, Francisco Cardoso, Andrew Singleton,
Summary Background Dystonia and parkinsonism may present as part of the same genetic disorder. Identification of the genetic mutations that underlie these diseases may help to shed light on the aetiological processes involved. Methods We identified two unrelated families with members with an apparent autosomal recessive, novel, young-onset, generalised form of dystonia parkinsonism. We did autozygosity mapping and candidate gene sequencing in these families. Findings High-density genome-wide SNP genotyping ...
Tópico(s): Hereditary Neurological Disorders
2008 - Elsevier BV | The Lancet Neurology
José Silva‐Cardoso, Daniel Brás, Filipa Canário-Almeida, Aurora Andrade, Leandro Licursi de Oliveira, F. Pádua, Cândida Fonseca, Nuno Bragança, Sofia Carvalho, Rui Soares, José Santos,
The current paradigm of medical therapy for heart failure with reduced ejection fraction (HFrEF) is triple neurohormonal blockade with an angiotensin-converting enzyme inhibitor (ACEI), a beta-blocker (BB) and a mineralocorticoid receptor antagonist (MRA). However, three-year mortality remains over 30%. Stimulation of counter-regulatory systems in addition to neurohormonal blockade constitutes a new paradigm, termed neurohormonal modulation. Sacubitril/valsartan is the first element of this new strategy. ...
Tópico(s): Heart rate and cardiovascular health
2019 - Elsevier BV | Revista Portuguesa de Cardiologia
Yoan Duhoo, Virginie Girault, Jeremy Turchetto, Laurie Ramond, Fabien Durbesson, Patrick Fourquet, Yves Nominé, Vânia Cardoso, Ana Filipa Sequeira, Joana L. A. Brás, C.M.G.A. Fontes, Gilles Travé, Nicolas Wolff, Renaud Vincentelli,
PDZ domains recognize PDZ Binding Motifs (PBMs) at the extreme C-terminus of their partner proteins. The human proteome contains 266 identified PDZ domains, the PDZome, spread over 152 proteins. We previously developed the "holdup" chromatographic assay for high-throughput determination of PDZ-PBM affinities. In that work, we had used an expression library of 241 PDZ constructs (the "PDZome V.1"). Here, we cloned, produced, and characterized a new bacterial expression library ("PDZome V.2"), which comprises ...
Tópico(s): Viral Infectious Diseases and Gene Expression in Insects
2019 - Springer Science+Business Media | Methods in molecular biology
Susana Brás, Raquel Sabino, André Oliveira, Helena Simões, Cândida Fernandes, Gabriela Marques-Pinto, Jorge Cardoso, Cristina Veríssimo,
Fungal invasive infections are rare in general population but are an emergent cause of infection in the immunocompromized population, especially in the solid organ transplant recipients. Herein the authors report a clinical case of a liver transplanted patient suffering a cutaneous co-existent infection with A. alternata as well as A. infectoria. To our knowledge this is the first case of cutaneous concomitant infection due to those two species reported not only in Portugal but also worldwide. The ...
Tópico(s): Fungal Plant Pathogen Control
2015 - Elsevier BV | Medical Mycology Case Reports
Diogo Coelho, Paula A. Lopes, Vânia Cardoso, P.I.P. Ponte, Joana L. A. Brás, Marta S. Madeira, Cristina M. Alfaia, Narcisa M. Bandarra, C.M.G.A. Fontes, José A. M. Prates,
Abstract The main goal of this study was to test a rational combination of pre‐selected carbohydrate‐active enzymes (CAZymes) and sulphatases, individually or in combination, in order to evaluate its capacity to disrupt Arthrospira platensis cell wall, allowing the release of its valuable nutritional bioactive compounds. By the end, a two‐enzyme constituted mixture (Mix), composed by a lysozyme and a α‐amylase, was incubated with A. platensis suspension. The microalga cell wall disruption was evaluated ...
Tópico(s): Enzyme Catalysis and Immobilization
2019 - Wiley | Journal of Animal Physiology and Animal Nutrition
Diogo Coelho, Paula A. Lopes, Vânia Cardoso, P.I.P. Ponte, Joana L. A. Brás, Marta S. Madeira, Cristina M. Alfaia, Narcisa M. Bandarra, Henri Gerken, C.M.G.A. Fontes, José A. M. Prates,
Abstract In this study, a rational combination of 200 pre-selected Carbohydrate-Active enzymes (CAZymes) and sulfatases were tested, individually or combined, according to their ability to degrade Chlorella vulgaris cell wall to access its valuable nutritional compounds. The disruption of microalgae cell walls by a four-enzyme mixture (Mix) in comparison with the control, enabled to release up to 1.21 g/L of reducing sugars (p < 0.001), led to an eight-fold increase in oligosaccharides release (p < 0.001), ...
Tópico(s): Enzyme Catalysis and Immobilization
2019 - Nature Portfolio | Scientific Reports
Mónica M. Costa, Luís Pio, Pedro Bule, Vânia Cardoso, Cristina M. Alfaia, Diogo Coelho, Joana L. A. Brás, C.M.G.A. Fontes, José A. M. Prates,
Abstract In the present study, 199 pre-selected Carbohydrate-Active enZymes (CAZymes) and sulfatases were assessed, either alone or in combination, to evaluate their capacity to disrupt Laminaria digitata cell wall, with the consequent release of interesting nutritional compounds. A previously characterized individual alginate lyase, belonging to the family 7 of polysaccharide lyases (PL7) and produced by Saccharophagus degradans , was shown to be the most efficient in the in vitro degradation of L. ...
Tópico(s): Enzyme Production and Characterization
2021 - Nature Portfolio | Scientific Reports
André Oliveira, Susana Brás, Rodrigo Carvalho, Cristina Amaro, Jorge Cardoso,
A 5-month-old female infant, preterm, exclusively breast-fed, presented with a 2-month history of erythematous, erosive, and crusted patches and plaques in a peri-oral, scalp, genital, and peri-anal distribution. A clinical diagnosis of zinc deficiency was confirmed by a low serum zinc level in the infant and decreased maternal breast milk zinc. Complete resolution occurred within two weeks of oral zinc supplementation. Acquired zinc deficiency is a rare nutritional disorder of infants. Early diagnosis ...
Tópico(s): Trace Elements in Health
2014 - University of California, Davis | Dermatology Online Journal
Anil Kumar Verma, Arun Goyal, Filipe Freire, Pedro Bule, I. Venditto, Joana L. A. Brás, Helena Santos, Vânia Cardoso, C. Bonifácio, Andrew Thompson, Maria João Romão, José A. M. Prates, L.M.A. Ferreira, C.M.G.A. Fontes, Shabir Najmudin,
The modular carbohydrate-active enzyme belonging to glycoside hydrolase family 30 (GH30) from Clostridium thermocellum (CtXynGH30) is a cellulosomal protein which plays an important role in plant cell-wall degradation. The full-length CtXynGH30 contains an N-terminal catalytic module (Xyn30A) followed by a family 6 carbohydrate-binding module (CBM6) and a dockerin at the C-terminus. The recombinant protein has a molecular mass of 45 kDa. Preliminary structural characterization was carried out on Xyn30A ...
Tópico(s): Polysaccharides and Plant Cell Walls
2013 - Wiley | Acta Crystallographica Section F Structural Biology and Crystallization Communications
Oriana Rainho Brás, Jean‐Philippe Cointet, Alberto Cambrosio, Leonor David, João Arriscado Nunes, Fátima Cardoso, Cármen Jerónimo,
This paper analyses the developmental dynamics of oncology research in Portugal during the second half of the twentieth century and early twenty first century. Grounding its conclusions in a scientometric analysis of a database of publications covering the period 1976–2015, the paper shows how the expansion of oncology research from the end of the 1990s through the 2000s is closely related to science and technology policy decisions in the country. The main actors of the institutional evolution of ...
Tópico(s): Global Health and Surgery
2017 - Springer Nature (Netherlands) | Scientometrics
Pedro Mendes‐Bastos, Susana Brás, Cristina Amaro, Jorge Cardoso,
... for more papers by this authorSusana Brás, Susana Brás Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorCristina Amaro, Cristina Amaro Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorJorge Cardoso, Jorge Cardoso Dermatology and Venereology Department, Hospital de ... for more papers by this authorSusana Brás, Susana Brás Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorCristina Amaro, Cristina Amaro Dermatology and Venereology Department, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, PortugalSearch for more papers by this authorJorge Cardoso, Jorge Cardoso Dermatology and Venereology Department, Hospital de ...
Tópico(s): Urticaria and Related Conditions
2014 - Wiley | JDDG Journal der Deutschen Dermatologischen Gesellschaft
Ana Maria Macedo, Cristiana Viana Cardoso, Joana Sofia Marques Neto, Catarina Amaral da Costa Brás da Cunha,
This article explores the role of vehicle repair workshops in car insurance fraud and how they might contribute to the reduction or increment of this type of crime, which has been an overlooked research area. The data collection method used was on-site semi-structured interviews through a convenience sample of twenty vehicle repair workshops in Oporto (Portugal). The results revealed that vehicle repair workshops facilitate insurance fraud mainly by cooperating with the vehicles owners and by not ...
Tópico(s): Crime Patterns and Interventions
2021 - Elsevier BV | International journal of law, crime and justice
Mónica M. Costa, Luís Pio, Pedro Bule, Vânia Cardoso, Marlene Duarte, Cristina M. Alfaia, Diogo Coelho, Joana L. A. Brás, C.M.G.A. Fontes, José A. M. Prates,
Green macroalgae, e.g., Ulva lactuca, are valuable bioactive sources of nutrients; but algae recalcitrant cell walls, composed of a complex cross-linked matrix of polysaccharides, can compromise their utilization as feedstuffs for monogastric animals. This study aimed to evaluate the ability of pre-selected Carbohydrate-Active enZymes (CAZymes) and sulfatases to degrade U. lactuca cell walls and release nutritive compounds. A databank of 199 recombinant CAZymes and sulfatases was tested in vitro ...
Tópico(s): Echinoderm biology and ecology
2022 - KeAi | Animal nutrition
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Tópico(s): Literature, Culture, and Criticism
1981 - | Revista do Centro de Estudos Portugueses
Lı́gia P. Brás, João A. Lopes, Carlos Raniery Paula dos Santos, J. P. Cardoso, José C. Menezes,
In this paper, multiblock partial least squares (MBPLS) was applied to model a multistage pharmaceutical process producing an active pharmaceutical ingredient (API) by fermentation. The aim is to model the final API's chromatographic purity in terms of each operating variable, establishing the relative contribution of each process stage. A balanced bootstrap algorithm was used to choose the best set of variables from each stage to obtain a model with the highest predictive capability. Seven variables ...
Tópico(s): Spectroscopy and Chemometric Analyses
2004 - Elsevier BV | Computer-aided chemical engineering/Computer aided chemical engineering
Henrique J. Cardoso, Marília I. Figueira, Cátia V. Vaz, Tiago M. A. Carvalho, Luís A. Brás, Patrícia A. Madureira, Paulo J. Oliveira, Vilma A. Sardão, Sílvia Socorro,
Tópico(s): Prostate Cancer Treatment and Research
2021 - Springer Nature | Cellular Oncology
Vânia Cardoso, Joana L. A. Brás, Inês F. Costa, L.M.A. Ferreira, L.T. Gama, Renaud Vincentelli, Bernard Henrissat, C.M.G.A. Fontes,
In nature, the deconstruction of plant carbohydrates is carried out by carbohydrate-active enzymes (CAZymes). A high-throughput (HTP) strategy was used to isolate and clone 1476 genes obtained from a diverse library of recombinant CAZymes covering a variety of sequence-based families, enzyme classes, and source organisms. All genes were successfully isolated by either PCR (61%) or gene synthesis (GS) (39%) and were subsequently cloned into Escherichia coli expression vectors. Most proteins (79%) were ...
Tópico(s): Studies on Chitinases and Chitosanases
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
Juliane Cristina Leme, Luíza dos Santos Banks, Yasmim Barbosa dos Reis, Jefferson Rosa Cardoso, Mário Hebling Campos, Paulo Roberto Pereira Santiago, Felipe Arruda Moura,
Running is a modality that has a large number of adepts, including women. Therefore, it is important to understand how sportswear can help women, with special attention to the breast movement. The aim of this study was to analyse the effect of different combinations of breast support and footwear on the breast movement during walking and running. Twenty women performed treadmill walking (5 km/h) and running (7 and 10 km/h) combining different footwear (barefoot, minimalist, and traditional) and breast ...
Tópico(s): Foot and Ankle Surgery
2020 - Elsevier BV | Journal of Biomechanics
Carole H. Sudre, Martina Bocchetta, Carolin Heller, Rhian S. Convery, Mollie Neason, Katrina Moore, David M. Cash, David L. Thomas, Ione Woollacott, Martha Foiani, Amanda Heslegrave, Rachelle Shafei, Caroline Greaves, John C. van Swieten, Fermín Moreno, Raquel Sánchez‐Valle, Barbara Borroni, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Christopher Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Giovanni B. Frisoni, Sandro Sorbi, Markus Otto, Henrik Zetterberg, Sébastien Ourselin, M. Jorge Cardoso, Jonathan D. Rohrer, Martin N. Rossor, Jason D. Warren, Nick C. Fox, Rita Guerreiro, José Brás, David L. Thomas, Jennifer Nicholas, Simon Mead, Lize C. Jiskoot, Lieke Meeter, Jessica Panman, Janne M. Papma, Rick van Minkelen, Yolanda Pijnenburg, Myriam Barandiarán, Begoña Indakoetxea, Alazne Gabilondo, Mikel Tainta, María de Arriba, Ana Gorostidi, Miren Zulaica, Jorge Villanúa, Zigor Díaz, Sergi Borrego‐Écija, Jaume Olives, Albert Lladó, Mircea Balasa, Anna Antonell, Núria Bargalló, Enrico Premi, Maura Cosseddu, Stefano Gazzina, Alessandro Padovani, Roberto Gasparotti, Silvana Archetti, Sandra E. Black, Sara Mitchell, Ekaterina Rogaeva, Morris Freedman, Ron Keren, David F. Tang‐Wai, Linn Öijerstedt, Christin Andersson, Vesna Jelić, Håkan Thonberg, Andrea Arighi, Chiara Fenoglio, Elio Scarpini, Giorgio Fumagalli, Thomas Cope, Carolyn Timberlake, Timothy Rittman, Christen Shoesmith, Robert Bartha, Rosa Rademakers, Carlo Wilke, Hans-Otto Karnarth, Benjamin Bender, Rose Bruffaerts, Philip Van Damme, Mathieu Vandenbulcke, Catarina B. Ferreira, Gabriel Miltenberger, Carolina Maruta, Ana Verdelho, Sónia Afonso, Ricardo Taipa, Paola Caroppo, Giuseppe Di Fede, Giorgio Giaccone, Sara Prioni, Veronica Redaelli, Giacomina Rossi, Pietro Tiraboschi, Diana Duro, Maria Rosário Almeida, Miguel Castelo‐Branco, Maria João Leitão, Miguel Tábuas‐Pereira, Beatriz Santiago, Serge Gauthier, Pedro Rosa‐Neto, Michele Veldsman, Toby Flanagan, Catharina Prix, Tobias Hoegen, Elisabeth Wlasich, Sandra Loosli, Sonja Schönecker, Elisa Semler, Sarah Anderl‐Straub, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Michela Pievani, Gemma Lombardi, Benedetta Nacmias, Camilla Ferrari, Valentina Bessi,
Frontotemporal dementia (FTD) is a heterogeneous group of neurodegenerative disorders with both sporadic and genetic forms. Mutations in the progranulin gene (GRN) are a common cause of genetic FTD, causing either a behavioural presentation or, less commonly, language impairment. Presence on T2-weighted images of white matter hyperintensities (WMH) has been previously shown to be more commonly associated with GRN mutations rather than other forms of FTD. The aim of the current study was to investigate ...
Tópico(s): Neurogenetic and Muscular Disorders Research
2019 - Elsevier BV | NeuroImage Clinical
Produção Nacional
Revisado por pares
Juliane Cristina Leme, Yasmim Barbosa dos Reis, Luíza dos Santos Banks, Jefferson Rosa Cardoso, Mário Hebling Campos, Felipe Arruda Moura,
Little attention has been given to factors which affects women running, such as proper footwear and breast support and their effects on spine. The objective of study was to analyse the influence of different breast support and footwear on vertebral posture during walking and running. Seventeen women (x¯ = 23.51; SD = 3.70 years) performed a treadmill walking (5 km/h) and running (7 and 10 km/h) with different footwear (barefoot, minimalist and traditional) and breast support (bare breast, everyday bra and ...
Tópico(s): Scoliosis diagnosis and treatment
2019 - Elsevier BV | Journal of Biomechanics