Limpar
76 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Jornais Acesso aberto

Jonathan Northcroft, Jonathan McCluskey, John Dugdale, Hala Jaber, Jane Cornwell, Barbara Hall, Frank Parker, Tony Barrell, Dave Wrighton, Sally Brock, Helen Davies, Nicholas Rufford, Angela Klemer, Rob Hughes, George Georgiou, John Munro, Mark Thatcher, Colin Brennan, John Peter, Amanda Ursell, Jonathan Miller, Andrew Longmore, Adam Sweeting, Professor Richard Scase, Susan d'Arcy, Joanna Duckworth, Gareth Walsh, Frank Whitford, Roz Coward, Nicolette Jones, Matthew Davis, Terence Blacker, David Gower, Karen Grahame, Kathryn Cooper, Ferdinand Mount, Matt Wolf, Jane Procler, William Lewis, William Ward, Lucy Hughes-Hallett, Maggie Barnes, Steven Poole, Nick Pitt, Neil Wormald, Richard Green, E P, Andrew Sullivan, Clive Davis, Sal Romaguera, Sally Brown, Rachel Royce, Andrew Porter, Dominic Bradbury, Tony Allen-Mills, Simon Wilde, Susan Berger, Craig Rowland director, Tom Walker, Robert Winnett, Jeremy Seal, Irwin Stelzer, Richard Mead joins, Roy Burrell, Matt Rudd, Peter Wilson, Rosie Millard, David Dougill, Jack Magnus, John Mortimer, Guy Williams, Christopher Hart, Piers Richmond, Stewart Lee, Jerry Daly, David Hewson, Norman Baker MP, Jonathon Carr-Brown, Margarette Driscoll, Hugh Canning, Geraldine Hackett Education Correspondent, Alan Maunder, Jeremy Clarkson, Andrew Stone, Manny Gatt managing director, Philip Smith, Edward Porter, David Cairns, Dean Nelson, Michael Portillo, Max Anderson, Giles Chapman, Peter Kemp, Anthony Peregrine, Wendy Sloane, Sarah Dempster, Kelly Holmes, Adrian Turpin, Dave Pollard, Anita Chaudhuri, Liz Edwards, Gray Walker, David Eimer, George Perry, Sam Tolchard, Adam Nathan, Anne Marie Conway, Andrew Porter Deputy Political Editor, Tim Charles, Alexandra Fuller, Brendan Bourne, David Walsh Chief Sports Writer, Christopher Silvester, Stuart Wavell, David Sanger, Pat Cash, Frances Spalding, Adam Nathan Defence Correspondent, Paul Gostick, Giles Hattersley, Chris Woodhead, Steve Boyd, Tim Jefferies, Simon Mills, Lucinda Kemeny, Tim Moore, Jasper Gerard, Paul Driver, Michael Woodhead, Garth Pearce, John Follain, Richard Brooks, Julie Earle-Levine, Shelley Von Strunckel, Alex Clark, David Leppard, Phill Baker, Paul Durman, Hannah Charlick, Mark Edwards, Fin Robb, Bob Walker, Leila Nadir-Jones, Rachel Bridge, Dave editor, Joss Bolton, Stephen Amidon, Bonnie Rakhit, Susan Clark, Harriet Perry, Judi Bevan, Graham Harvey, Blower, Alistair Baker managing director, William Shaw, Rowena Hurst, Steve Moxon, Lara Atkin, Raymond Keene, Peter Martin, Douglas Alexander, Stanley Stewart, Cosmo Landesman, Zoe Brennan, Robbie Hudson, Jim Irvin, Diana Wright, Kipper Williams, Christopher Smallwood, Ruby Wax, Alice Douglas, Lyn Cooper, Stephen Jones, Aleen Medcalf, Dominic O'Connell, Louise Armitstead, Uzi Mahnaimi, Nick Cain, Robbie Burns, Dianne Thompson, Adrienne Connors, Michael Wright, Natalie Graham, Tim Moorey, Caroline Donald, Jon Butler, Jeremy Lewis, Nick Rennison, Juggy D, Jessica Brinton, David Walsh, Mark Taha, Trevor Lewis, Jack Grimston, Gareth Southgate, Robert Ballantyne, Campbell Crawford, Bryan Appleyard, Colin McDowell, Stephen Armstrong, Burlington Bertie, John Elliott, Bethan Cole, Nicholas Milton, David Price, Roland White, Shane Watson, Timothy Warriner, Abul Taher, Dr Vernon Coleman, Richard Brooks Arts Editor, Simon Welis, Richard Rae, Mark Franchetti, Ray Hutton, Victoria Segal, Professor Grideon Garter, Louise Armistead, Hutton, Reginald Phillips, Jim Anderson, Michael Sheridan, Peter Stringfellow, Clare Francis, Deborah Scroggins, John Harlow, Dileep Premachandran, Karin Goodwin, Marvin Pryce-Jones, Bob Davis, Simon Brooke, Tom Baird, Dipesh Gadher, Chris Chataway, Second Dawe, A A Gill, A M C, Matthew Campbell, Helen James, Oliver Popplewell, Stephen Pettitt, Claudia Croft, Will Iredale, Jonathan Leake Science Editor, Imre Karacs, Camile Paglia, Peter Munro, Naomi Caine, Sally Kinnes, Daniel Emery, John Kerry, Peter Done managing director, Ben Dowell, Minette Marrin, Peter Schmeichel, Simon Buckland, John Aizlewood, Jeremy Lazell, Stan Bowles, Graham Norwood, Joe Lovejoy, Andrew Frankel, John Cornwell, Dr John Fox, William Lewis Business editor, David Budworth, Hugh Pearman, Dan Cairns, Stewart Mitchell, Sean Williams, Giorgio Locatelli, Mike Hammond, Kevin McCloud, Frances Barber, Matthew Goodman, India Knight, Nina Goswami, Dominic Rushe, Richard Lewis, Sian Griffiths, Karen Robinson, Helen Stewart,

... Like?—The Personality Test (BBC1, 8pm) Expect fireworks Brainiac: Science Abuse (Sky One, 8pm) At least it' ...

2004 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Hans H. Wandall, Sandrine Pizette, Johannes W. Pedersen, Heather Eichert, Steven B. Levery, Ulla Mandel, Stephen M. Cohen, Henrik Clausen,

The Drosophila genes, brainiac and egghead, encode glycosyltransferases predicted to act sequentially in early steps of glycosphingolipid biosynthesis, and both genes are required ... in Drosophila. egghead encodes a β4-mannosyltransferase, and brainiac encodes a β3-N-acetylglucosaminyltransferase predicted by in ... in vivo evidence for this hypothesis. egghead and brainiac mutants lack elongated glycosphingolipids and exhibit accumulation of ... depend on the core structure. The Drosophila genes, brainiac and egghead, encode glycosyltransferases predicted to act sequentially ...

Tópico(s): Sphingolipid Metabolism and Signaling

2004 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

Andrew Robson, Janice Turner, Robert Cole, Paul Lightfoot, Amanda Ursell, Simon Barnes, Simon Hills, Louette Harding, David Rose, John Mulvey, Karen Russell, Carol Midgley, Melissa Katsoulis, Lucia Van Der Post, Pat Gibson, Dominic Walsh, Dr David Harper, Jessica Long, Jenny MacArthur, Ben Machell, Rupert Wright, Tina Gaudoin, Adam Sherwin Media Correspondent, Lucy Sweeney, Tim Teeman, Catherine Bennion-Pedley, John Talbot, Richard Dawkins, Oliver Kay, Stephen Anderton, Clive James, Pete Paphides, Geoffrey Dean, Christina Koning, Naomi Shragai, Neil Harman Tennis Correspondent, Suzi Godson, Kate Saunders, Matthew Pryor, Matt Dickinson, Jeffrey Deaver Thriller Writer, Chris Campling, Andrew Collins, Helen Nugent, Christopher Martin-Jenkins Chief Cricket Correspondent, Allan Mallinson, Bill Nighy, Graham Searjeant Personal Investor, John Connolly, James Collard, Nigel Kendall, Nick Szczepanik, Keith Hopcroft, Ian Johns, Matthew Parris, Mark Bridge, Anjana Ahuja, George Caulkin, Hugh Barrett, Russell Jenkins, Caitlin Moran, Sheila Keating, Nick Edmans, Iain Finlayson, B. G. W. Jamieson, Peter Riddell, Ben MacIntyre, Claire Keegan, Tim Parks, Tony Woolcott, David Hutcheon, Bojan Pancevski, Patrick Foster, Anna Shepard, Alexandra Blair Education Correspondent, Cath Urquhart Travel Editor, David Staples, Jilly Cooper Bonkfest Author, Rachel Cusk, Paul Hoggart, Julia Brookes, Hannah Betts, Penny Wark, Clive Davis, Elizabeth Judge, Gabrielle Starkey, Patrick Kidd, Graham Stewart, Robin Pagnamenta, Nancy Durrant, Jane MacArtney, Dino Buzzati, Mike Pattenden, Victoria Segal, Tim Reid, James Rossiter Professional Services Correspondent, Richard Turner, Graham Campbell, Tim Moore, Ed Potton, Adam Thorpe, Tony Rees, Mark Henderson Science Editor, Patrick Hosking Banking and Finance Editor, John Westerby, Simon de Bruxelles, Feargal Sharkey, Magnus Grimond, Robin Pagnamenta Health Industries Correspondent, Sarah Birke, Kaveh Solhekol, Jeremy Page, Rick Jones, Andrew G. Marshall, Erica Wagner, Richard Cloete, Joe Cocker, Owen Slot Chief Sports Reporter, David Hands Rugby Correspondent, Paul Simons, Steve Jelbert, Anne Ashworth, Dominic Kennedy, Richard Ehrlich, Dominic Maxwell, Mark Hodkinson, Philip Webster, Mark Henderson, Nigel Hawkes Health Editor, Ashling O'Connor, Benedict Nightingale, Dr Thomas Stuttaford, Stephen Dalton, Richard Morrison, Tom Chesshyre, Tony Halpin, Simon Crompton, Olav Bjortomt, GP, Fiona Hamilton, Christopher Irvine, Elizabeth Judge Telecoms Correspondent, Mary Hodgson, Ceila Dodd, Neelam Verjee, John Gudgeon, Mike Barnes, Hazhir Teimourian, Jane MacQuitty, Alexandra Blair, Peter Lansley, Jill Hartley, Adam Zamoyski, Robert Lindsay, Angus Macleod Scottish Political Editor, Jane Knight, Tony Turnbull, Philip Howard, Thomas Blomberg, Ben Hoyle Arts Reporter, James Bone, James Ducker, , Rachel Campbell-Johnston, Martin Aston, Jeremy Whittle, Kevin Eason, Donal O'Shea, Mike Owen joint managing director, Stephen McClarence, A. C. Grayling, Tom Bawden, William Dalrymple, Gary Jacob, Daniel Finkelstein, Michael Harvey, Dalya Alberge Arts Correspondent, Jo Morris, David Sharrock Ireland Correspondent, Troy Garity, Rhys Blakely, Rob Eastaway, Edward Gorman, David Seabrook, Aggie MacKenzie, Russell Kempson, Adam Hirschovits, Sarah Vine, Mark Atherton, Jane Wheatley, James Rossiter, Andrew Salmon, Sally Baker, Tim Ruffle, Neel Mukherjee, David Baddiel, Rob Wright, ZoË Strimpel, Edward Gorman Motor Racing Correspondent, Raymond Keene, Mark Tully, Matt Hughes, Rebecca O'Connor, Emily Mathieson, Nigel Hawkes, Patrick Hosking, Richard Owen, Thomasina Miers, Kevin Maher, Tom Dart, Julian Muscat, Nicholas Clee, Joanna Pitman, Robert Crampton, Steve Hawkes, John Trowell, Tim Hames, Malcolm Boyden, Christopher McCall, Alan Franks, Neil Fisher, Celia Dodd, Helen Pridham, Bess Twiston Davies, Ian Prentice, Rob Nash, John Naish, Geoffrey Rowell, Ben Myers, Martin Waller, Chris Ayres, James Jackson, Carl Mortished International Business Editor, Louise Cohen, Leo Lewis, Alyson Rudd, Alice Miles, Judith Heywood, T. C. Boyle, Simon Reeve, Will Hide, Bryce Elder, Giles Smith, Christina Hardyment, Cath Urquhart, Gordon L. Weil, David Brown, Alice Bowe, Zahid Hussain, Greg Hurst Political Correspondent, David Aaronovitch, Steve Jeal, Christopher Somerville, Mark Souster, John Murrell, Clare Lazaro, Christine Seib, David Chater, Will Pavia, Sam Marlowe, Wendy Ide, John Bungey, Lucy Bannerman, Giles Coren, Martin Fletcher, Ben Webster Transport Correspondent, Vinny Lee, Warwick Thompson, Ray Boulger senior technical manager, Debra Craine, Vic Reeves, Stuart Hood, Allan Simmons, Norman Harris, Ruth Gledhill Religion Correspondent, Candida Crewe, Bridget Frust, Elizabeth Colman, Nick Wyke, David Hands, Jonathan Richards, Derek Arthur Listener Crossword co-editor, Derwent May, Hugo Rifkind, Kate Muir, Harish Joshi, Tom Whitwell, Lisa Armstrong, James Harding Business Editor, Tom Baldwin, Martyn Palmer, GrÁinne Gilmore Deputy Personal Finance Editor, Ann Treneman, David Robertson Business Correspondent, John Hopkins Golf Correspondent, Gordon Ramsay, James Shuttleworth, Christine Buckley Industrial Editor, Jo Carlowe, Ross Leckie, Marcel Berlins, James Charles, Tony Cascarino, Rosemary Bennett Social Affairs Correspondent, Mike Mulvihill, Matthew Cresswell, Jonathan Clayton, Philip Webster Political Editor, Thomas Catán, Virginia Blackburn, Amanda Craig, Richard Beeston Diplomatic Editor, Paula Tallon director of direct tax, Angus Batey, James Christopher, John Mather, David Robertson,

... call Midge Laughing in the face of danger Brainiac, the 'science' show that loves to blow things ...

2007 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Reto Mu ̈ller, Friedrich Altmann, Dapeng Zhou, Thierry Hennet,

Mutations at the Drosophila melanogaster brainiac locus lead to defective formation of the follicular epithelium during oogenesis and to neural hyperplasia. Thebrainiac gene encodes a type II ... mammalian β1,3-glycosyltransferases. We have cloned the brainiac gene from D. melanogastergenomic DNA and expressed it ... glycolipids from mammalian cells. Methylation analysis of the brainiac reaction product revealed a β1,3 linkage between ... substrates and failed to rescue a homozygous lethal brainiac allele, indicating that these proteins are paralogous and ...

Tópico(s): Lysosomal Storage Disorders Research

2002 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

Sally Brock, V S, Professor Gideon Garter, Ashia Hansen, Ferdinand Mount, Polly Poynbee, David Hopkins, Neil Wormald, Fiona Ronaldson, Kingstom Smith, Roger Panding, Joseph Dunn, Martin James, Anthony Sattin, Rosie Millard, Phil Baty, David Hewson, Hugh Canning, Sarah Dempster, Kevin Jackson, Peter Millar, Ashley Stoop, Mark Fitzsimons, Tom Tom, Catherine Lunken, John Humphrys, Nicholas Hellen, Danny Scott, Alicia Wyllie, Jim McGill, Paul Martin, Chemmy Alcott, Ed Porter, Adrain Furnham, Nick Rennison, T Tarlton, Bob Dwuer, Bryan Appleyard, John Elliott, Ali Allen, Maurice Chittenden, Richard Brooks Arts Editor, Brian Smyth, Godfrey Smith, Alex Pell, Matthew Campbell, Louise Johncox, Enda Leahy, Jacqui Goddard, Graham Norwood, David Budworth, William Lewis Business editor, Jane Horrocks, Mrs Mills, Susannah Price, Sarah Baxter, David McLeish, Bob Dwyer, Ed Hughes, Pamela Coleman, Jason Dawe, William Gray, Jonathan Northcroft, Hala Jaber, Matthew Wall, Colin Coyle, Felice Hardy, Peter Whittle, Andrew Longmore, Melanie Eskenazi, Caroline Brannigan, Paul Marinko, Steven Poole, E P, Andrew Sullivan, Clive Davis, Doug Bradshaw, Alan Milburn, Colin Batsman, Tom Otley, Christobel Flood, Fiona MacDonald-Smith, Anna Bruning, Peter Jones, David Bond, Carole Tucker, Frank Dobson, Alasdair Reid, D Taylor, Gilly Banyard, Victoria Segal, Edward Porter, Dave Pollard, Rosy Cheeks, Patrick Maxwell, Shelley von Strunckel, Geoffrey Wheatcroft, Doug Sager, Christopher Silvester, Stuart Wavell, Paul Donovan, David Howgrave-Graham, Steve Boyd, Garth Pearce, Richard Brooks, Stuart Andrews, David Leppard, Sarah Rundell, Graham Bell, Scott Atkins, Alan Combes, Gareth Huw Davies, David Cracknell, Jayesh Ghaghda, Katrina Manson, Greg Hadfield, Diana Wright, Clare Short, Barry Flatman, Kenneth Clarke, Natalie Graham, David Walsh, Jack Grimston, Andreas Viestad, Stephen Armstrong, Bethan Cole, Michael Sheridan Far East Correspondent, N R, Richard Woods, Martin Pilcher, Ray Hutton, Chris woodhead, Ian Thomson, A A Gill, Lord Fowler, Michael Bright, Brian Doogan, Ben Dowell, Clifford Bishop, John Cornwell, Jonathan Futrell, Victor Bryant, Hugh Pearman, Tom Deveson, Martin Booth, Ann Waite, Richard Lewis, Helen Stewart, John Dugdale, Barbara Hall, Nigel Botherway, Nicholas Rufford, Stuart Shaw, Rob Hughes, John Peter, Susan d'Arcy, Ivo Tennant, Markie Robson-Scott, David Smith, Tim Richards, David Cracknell Political Editor, Dipesh Gadher Transport Correspondent, Tom English, Alastair Campbell, Lawrence Dallaglio, Susanna Doyle, John McCarthy, Sir Brian Barder, Stewart Lee, Peter Conradi, Debbie Taylor, Helen Kenny, Patricia Nicol, John O'Donnell, Brain Deogan, Jeremy Guscott, Christine Toomey, Vincent Crump, Chris Woodhead, Harvey Cole, Alex Clark, Mark Edwards, Rachel Bridge, Susan Clark, Rajiv Radhakrishnan Pinner, Stuart Miles, Chloë Beeney, Sean Newsom, Boris Becker, Lizzie McGuire, Raymond Keene, Peter Howarth, Stephen Jones, Paul Sullivan, Louise Armitstead, Nick Cain, Melinda Stevens, Tim Moorey, Gary Buchanan, Trevor Lewis, Victoria O'brien, Roland White, Peter Hardy, Alex Fortune, Stuart Derrick, Richard Rae, Mark Franchetti, Jon Ungoed-Thomas, Susan Elkin, Michael Sheridan, Barry Collins, John Waples, Hunter Davies, Jeremy Hart, Ralph Oswick, Roger Holmes, Stephen Pettitt, Maria McErlane, Mark Hodson, Andrew Frankel, George, Joe Lovejoy, Dan Cairns, David Grylls, David Smith Economics Editor, Simon Howard, Reginald Williams, Dominic Rushe, David Newbury, Fred Redwood, Helen Davies, Daniel Carpenter, Pam Barrett, Barry Toomey, Frank Whitford, Kathryn Cooper, William Lewis, P D, John Simpson, Humphrey Carpenter, Andrew Porter, Tony Allen-Mills, Simon Wilde, Robert Sandall, Rosie Garthwaite, John R Bradley, Robert Winnett, Irwin Stelzer, Brian Glanvilla, Peter Wilson, David Dougill, Rachel Dobson, David Coulthard, Geraldine Hackett Education Correspondent, Jeremy Clarkson, David Cairns, Lydia Slater, Phil Craigie, Paula Robinson, Dame Marie Stubbs, Paul Ham, Roger Eglin, Lucinda Kemeny, Jasper Gerard, Paul Driver, Ian Hawkey, Oleg Gordievsky, Paul Durman, Phill Baker, Lisa Grainger, Gerald Hartup, Arnie Wilson, Lyn Plumpton, Frank Morpeth, Sharron Davies, Christina Lamb, Gillian Anderson, Douglas Alexander, Cosmo Landesman, Dominic O'Connell, Erica Jong, Niall Toner, Caroline Donald, Alan Beale, Colin McDowell, Aleks Sierz, Ron Clarke, Christopher Goodwin, David Lepard, Shane Watson, Judith O'Reilly, Jonathan Leake, Amanda Craig, Clare Francis, Jonathan Leake Science Editor, Sally Kinnes, Naomi Caine, David Wickers, Peter Almond, Minette Marrin, Andrew Davidson, Paul Stephen Lubicz, Zara Phillips, John Alzlewood, Catriona Cook, Joanna Simon, David Robertson, Matthew Goodman, Alistair Cook,

... 30pm) Girl power Superstars (BBC1, 8pm) Weirdest science Brainiac: Science Abuse (Sky One, 8pm) Most Gallic French ...

2003 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Tilo Schwientek, Birgit Keck, Steven B. Levery, Mads A. Jensen, Johannes W. Pedersen, Hans H. Wandall, Mark R. Stroud, Stephen M. Cohen, Margarida Amado, Henrik Clausen,

The Drosophila genes fringe and brainiac exhibit sequence similarities to glycosyltransferases. Drosophila and mammalian fringe homologs encode UDP-N-acetylglucosamine:fucose-O-Ser beta1,3-N-acetylglucosaminyltransferases ... of Notch family receptors. The biological function of brainiac is less well understood. brainiac is a member of a large homologous mammalian ... putative mammalian homologs with highest sequence similarity to brainiac encode UDP-N-acetylglucosamine:beta1,3-N-acetylglucosaminyltransferases ( ...

Tópico(s): Lysosomal Storage Disorders Research

2002 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Hans H. Wandall, Johannes W. Pedersen, Chaeho Park, Steven B. Levery, Sandrine Pizette, Stephen M. Cohen, Tilo Schwientek, Henrik Clausen,

The neurogenic Drosophila genes brainiac and egghead are essential for epithelial development in the embryo and in oogenesis. Analysis of egghead and brainiac mutants has led to the suggestion that the ... genes function in a common signaling pathway. Recently, brainiac was shown to encode a UDP- N -acetylglucosamine: ... to form the precursor arthroseries glycosphingolipid substrate for Brainiac, Manβ1–4Glcβ1–1Cer. Egghead is unique among eukaryotic ... of arthroseries glycolipids in invertebrates. We propose that brainiac and egghead function in a common biosynthetic pathway ...

Tópico(s): Lysosomal Storage Disorders Research

2003 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Joel S. Griffitts, Danielle L. Huffman, Johanna L. Whitacre, Brad Barrows, Lisa D. Marroquin, Reto Müller, Jillian R. Brown, Thierry Hennet, Jeffrey D. Esko, Raffi V. Aroian,

... previously identified bre-5 has homology to Drosophila brainiac (brn) and that egh-brn likely function as ... previously identified bre-5 has homology to Drosophila brainiac (brn) and that egh-brn likely function as ... bre-5 shares sequence similarity to the Drosophila brainiac (brn) gene and since egh and brn function ... NIH Image. bre-5 Rescue of the Drosophila brainiac Mutant—The bre-5 cDNA was cloned into ... Molecular Biology, University of Zürich). Flies carrying UAS-brainiac and UAS-β3GnT-IV (a human N-acetylglucosaminyltransferase) ...

Tópico(s): Insect Pest Control Strategies

2003 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Benedikt Vollrath, Kevin Fitzgerald, Philip Leder,

The neurogenic gene brainiac was first isolated in Drosophila melanogaster, where it interacts genetically with members of the Notch signaling cascade. We have isolated a murine homologue of the Drosophila brainiac gene and delineated its highly specific expression pattern ... in the adult hippocampus. Targeted deletion of mouse Brainiac 1 expression leads to embryonic lethality prior to ... do not appear to implant, indicating that mouse Brainiac 1, likely a glycosyltransferase, is crucial for very ...

Tópico(s): Neurobiology and Insect Physiology Research

2001 - Taylor & Francis | Molecular and Cellular Biology

Artigo Acesso aberto Revisado por pares

Iskra Katic, Ludovic Vallier, Iva Greenwald,

... bre-5 is the homolog of D. melanogaster brainiac. BRE-5/Brainiac catalyzes a step in the synthesis of glycosphingolipids, ...

Tópico(s): Plant Stress Responses and Tolerance

2005 - Oxford University Press | Genetics

Revisão Acesso aberto Revisado por pares

Christos Fidas, Dimitrios P. Lyras,

... aiming at identifying and authenticating individuals given their brainiac activity within specific contexts of use. Indeed, utilizing EEG signals that are derived from brainiac activities can be used for tackling existing UA ...

Tópico(s): Biometric Identification and Security

2023 - Institute of Electrical and Electronics Engineers | IEEE Access

Artigo Revisado por pares

Sandrine Pizette, Cathérine Rabouille, Stephen M. Cohen, Pascal P. Thérond,

... relies on the activity of the Egghead and Brainiac glycosyltransferases. Mutations in these two enzymes abolish GSL ... signaling in vivo. Here, we use egghead and brainiac mutants to show that GSLs are necessary for ...

Tópico(s): Cellular transport and secretion

2009 - The Company of Biologists | Development

Artigo Acesso aberto Revisado por pares

Ya‐Wen Chen, Johannes W. Pedersen, Hans H. Wandall, Steven B. Levery, Sandrine Pizette, Henrik Clausen, Stephen M. Cohen,

... chains in vivo. The Drosophila glycosyltransferases Egghead and Brainiac are responsible for the 2nd and 3rd steps ... behavioral defects, which are also observed in viable brainiac mutants, suggesting that proper locomotion and coordination primarily ...

Tópico(s): Cellular transport and secretion

2007 - Elsevier BV | Developmental Biology

Artigo Revisado por pares

Brad S. Coates, Douglas V. Sumerford, Richard L. Hellmich, Leslie C. Lewis,

... nubilalis midgut tissue, and showed homology to Drosophila brainiac (brn) and Caenorhabditis elegans bre5 proteins. Single nucleotide ...

Tópico(s): Insect and Pesticide Research

2007 - Elsevier BV | Insect Biochemistry and Molecular Biology

Revisão Acesso aberto Revisado por pares

Lori Marino,

... also other senses such as touch. Dolphins are brainiacs. Dolphin brains are organized differently from human brains, ... animals. Like humans, dolphins are, without a doubt, brainiacs of the animal kingdom. What is dolphin cognition? ...

Tópico(s): Cephalopods and Marine Biology

2004 - Elsevier BV | Current Biology

Artigo Acesso aberto Revisado por pares

Andrew Swan, Sirine Hijal, Andres Hilfiker, Beat Suter,

... describe new roles for the genes dunce ( dnc ), brainiac ( brn ) and fs(1)Yb , and we identify ...

Tópico(s): Developmental Biology and Gene Regulation

2001 - Cold Spring Harbor Laboratory Press | Genome Research

Carta Acesso aberto Revisado por pares

Yan P. Yuan, Jörg Schultz, Marek Mlodzik, Peer Bork,

... significant similarities of FNG-like proteins to Drosophila Brainiac (BRN; 8Goode S. Morgan M. Liang Y.-P. ... involved in pattern formation such as Fringe and Brainiac, may be secreted glycosyltransferases might come as a ...

Tópico(s): Ubiquitin and proteasome pathways

1997 - Cell Press | Cell

Artigo Revisado por pares

Scott R. Goode, Michael Melnick, Tze-Bin Chou, Norbert Perrimon,

... Previous studies have suggested that the neurogenic gene brainiac (brn) is specifically required for epithelial development (Goode, ...

Tópico(s): Wnt/β-catenin signaling in development and cancer

1996 - The Company of Biologists | Development

Artigo Revisado por pares

Scott R. Goode, David A. Wright, Anthony P. Mahowald,

... characterized the function of a new neurogenic locus, brainiac (brn), during oogenesis. Homozygous brn females lay eggs ...

Tópico(s): Neurobiology and Insect Physiology Research

1992 - The Company of Biologists | Development

Artigo Acesso aberto Revisado por pares

Petar Vukmirović, Jasmin Christian Blanchette, Simon Cruanes, Stephan Schulz,

Abstract Decades of work have gone into developing efficient proof calculi, data structures, algorithms, and heuristics for first-order automatic theorem proving. Higher-order provers lag behind in terms of efficiency. Instead of developing a new higher-order prover from the ground up, we propose to start with the state-of-the-art superposition prover E and gradually enrich it with higher-order features. We explain how to extend the prover’s data structures, algorithms, and heuristics to $$\lambda $$ ...

Tópico(s): Formal Methods in Verification

2021 - Springer Science+Business Media | International Journal on Software Tools for Technology Transfer

Revisão Acesso aberto Revisado por pares

Ana M. Espinosa‐Oliva, Juan García‐Revilla, Isabel M. Alonso-Bellido, Miguel Ángel Burguillos,

For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as regulators of apoptosis or inflammation to having a wider range of functions. In this mini review, we focus on the most recent "non-apoptotic" roles of caspases in the CNS, particularly in neurons, astrocytes and oligodendrocytes. Non-apoptotic caspase functions in microglia have already been reviewed extensively elsewhere. Here we discuss the involvement of caspases in the activation ...

Tópico(s): Autophagy in Disease and Therapy

2019 - Frontiers Media | Frontiers in Cellular Neuroscience

Artigo Acesso aberto Revisado por pares

Elizabeth Palaima, Nancy Leymarie, Dave Stroud, Md. Mizanur Rahman, Jonathan Hodgkin, Maria J. Gravato‐Nobre, Catherine E. Costello, John F. Cipollo,

... a third encodes is a homolog of Drosophila brainiac (brn) and encodes a UDP-GlcNAc:βMan N- ...

Tópico(s): Microbial Metabolites in Food Biotechnology

2010 - Elsevier BV | Journal of Biological Chemistry

Artigo

Sudhanva Gurumurthi,

Disk drives play a critical role on the performance of I/O intensive applications. Over the years, disk drive performance has grown as a result of advances in magnetic recording density and faster rotational speeds. In essence, the performance driver in disks has been the data rate. In this paper, we show that data rate is going to be increasingly difficult to optimize, due to power/thermal constraints. We argue that disk drive designers should instead focus their efforts on providing more computational ...

Tópico(s): Parallel Computing and Optimization Techniques

2007 - Association for Computing Machinery | ACM SIGOPS Operating Systems Review

Artigo Revisado por pares

Stephan Schulz,

We describe the superposition-based theorem prover E. E is a sound and complete prover for clausal first order logic with equality. Important properties of the prover include strong redundancy elimination criteria, the DISCOUNT loop proof procedure, a very flexible interface for specifying search control heuristics, and an efficient inference engine. We also discuss strength and weaknesses of the system.

Tópico(s): Formal Methods in Verification

2002 - IOS Press | AI Communications

Artigo Acesso aberto Revisado por pares

Xiaomei Bai, Dapeng Zhou, Jillian R. Brown, Brett E. Crawford, Thierry Hennet, Jeffrey D. Esko,

... Interestingly, β3GalT1, β3GalT5, and the homologous Drosophila protein Brainiac also contain Cys residues in their putative transmembrane ...

Tópico(s): Carbohydrate Chemistry and Synthesis

2001 - Elsevier BV | Journal of Biological Chemistry

Artigo Revisado por pares

Susan E. Cole, Meredith S. Mao, Stuart H. Johnston, Thomas Vogt,

Tópico(s): Genomics and Phylogenetic Studies

2001 - Springer Science+Business Media | Mammalian Genome

Artigo Revisado por pares

Scott R. Goode, Norbert Perrimon,

Tópico(s): Mechanisms of cancer metastasis

1997 - Cold Spring Harbor Laboratory Press | Cold Spring Harbor Symposia on Quantitative Biology

Revisão Revisado por pares

Margaret M. Morgan, Anthony P. Mahowald,

... to the germline stem cells. Both gurken and brainiac are required in the germline, and the Egfr, ...

Tópico(s): Plant Reproductive Biology

1996 - Wiley | Archives of Insect Biochemistry and Physiology

Artigo Acesso aberto Revisado por pares

Scott R. Goode, Margaret M. Morgan, Yuanping Liang, Anthony P. Mahowald,

brainiac (brn)is involved in a number of developmental events. In addition to being required zygotically for ...

Tópico(s): Kruppel-like factors research

1996 - Elsevier BV | Developmental Biology