Produção Nacional
Revisado por pares
Camila Zaverucha-do-Valle, Louise A. Mesentier‐Louro, Fernanda Gubert, Nicoli Mortari, Ana Beatriz Padilha, Bruno Diaz Paredes, André Luiz Mencalha, Eliana Abdelhay, Camila da Silva Teixeira, Fernanda Guimarães Meireles Ferreira, Fernanda Tovar‐Moll, Sérgio Augusto Lopes de Souza, Bianca Gutfilen, Rosalia Méndez‐Otero, Marcelo F. Santiago,
In adult mammals, the regeneration of the optic nerve is very limited and at the moment there are several groups trying different approaches to increase retinal ganglion cell (RGC) survival and axonal outgrowth. One promising approach is cell therapy. In previous work, we performed intravitreal transplantation of bone-marrow mononuclear cells (BMMCs) after optic nerve crush in adult rats and we demonstrated an increase in RGC survival and axon outgrowth 14 days after injury. In the present work, we ...
Tópico(s): Mesenchymal stem cell research
2014 - Elsevier BV | Brain Research
Produção Nacional
Revisado por pares
Christiana Maia Nobre Rocha de Miranda, Carol Pontes de Miranda Maranhão, Fabiana Maia Nobre Rocha Arraes, Igor Gomes Padilha, Lucas de Pádua Gomes de Farias, Mayara Stephanie de Araujo Jatobá, Anna Carolina Mendonça de Andrade, Bruno Gomes Padilha,
A tomografia computadorizada multislice é, atualmente, a modalidade de imagem de escolha para a avaliação dos seios paranasais e das estruturas adjacentes. Ela tem sido cada vez mais utilizada para a avaliação das variações anatômicas, identificando-as de forma precisa e com elevados detalhes anatômicos. Algumas variações anatômicas podem predispor a sinusopatias e constituir regiões de alto risco para lesões e complicações durante atos operatórios. Portanto, o reconhecimento dessas variações é ...
Tópico(s): Nasal Surgery and Airway Studies
2011 - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem | Radiologia Brasileira
Produção Nacional
Fernanda Vieira Cardoso, Anderson Ricardo Cantareli da Silva, Anna Carolina Flumignan Bucharles, Manuela Bernardi da Silva, Marcela Gomes Ferraz, Maria Victória Ferreira Piccoli, Melissa Alves Aires Marques, Natália Carvalho Gomes David, Natalia de Queiroz Padilha, Bruno Augusto Lopes,
Objetivo: Apresentar os aspectos mais importantes das causas, diagnósticos e terapias do abdome agudo. Revisão bibliográfica: O abdome agudo é caracterizado pela presença de dor e sensibilidade abdominal de início súbito e evolução progressiva, com duração máxima de 5 dias e origem não traumática. A partir disso, deve-se avaliar a necessidade de observação em regime hospitalar, exames adicionais e/ou indicação cirúrgica imediata. Após avaliação clínica, pode-se tomar a decisão de realizar a investigação ...
Tópico(s): Evasion and Academic Success Factors
2022 - Revista Eletronica Acervo Saude | Revista Eletrônica Acervo Saúde
Produção Nacional
Revisado por pares
Denizia Padilha, Bruno München Wenzel, Nilson Romeu Marcílio, Arthur D.B. Silva, Lucas P. Cavalcanti, Marcelo Godinho,
Acid leaching was investigated to remove phosphorus from the ashes of thermally-treated (gasification and combustion process) footwear leather waste in order to obtain a good quality raw material for the production of a ferrochromium alloy. The ash contained high amounts of chromium (55 wt.% Cr2O3) and phosphorus (1.42 wt.% P). The following key factors were selected for study: temperature, H2SO4 concentration in the leaching solution, acid solution/ash ratio and the particle size of the ash. The response ...
Tópico(s): Recycling and Waste Management Techniques
2012 - Elsevier BV | International Journal of Mineral Processing
Produção Nacional
Revisado por pares
Alexandre de Oliveira Jorgetto, R.I.V. Silva, M.M. Longo, Margarida Júri Saeki, Pedro de Magalhães Padilha, Marco Antônio Utrera Martines, BRUNO PRIOR ROCHA, Gustavo R. Castro,
The present study describes the incorporation of a complexing agent, dithiooxamide, into microcrystalline cellulose for use in the pre-concentration of Cu(II) and Cd(II) ions from aqueous samples. The FTIR spectrum of the adsorbent exhibited an absorption band in the region of 800 cm−1, which confirmed the binding of the silylating agent to the matrix. Elemental analysis indicated the amount of 0.150 mmol g−1 of the complexing agent. The adsorption data were fit to the modified Langmuir equation, ...
Tópico(s): Recycling and Waste Management Techniques
2012 - Elsevier BV | Applied Surface Science
Produção Nacional
Revisado por pares
Louise A. Mesentier‐Louro, Camila Zaverucha-do-Valle, Almir Jordão da Silva‐Junior, Gabriel Nascimento‐dos‐Santos, Fernanda Gubert, Ana Beatriz Padilha de Figueirêdo, Ana Luiza Torres, Bruno Diaz Paredes, Camila da Silva Teixeira, Fernanda Tovar‐Moll, Rosalia Méndez‐Otero, Marcelo F. Santiago,
Bone marrow-derived cells have been used in different animal models of neurological diseases. We investigated the therapeutic potential of mesenchymal stem cells (MSC) injected into the vitreous body in a model of optic nerve injury. Adult (3–5 months old) Lister Hooded rats underwent unilateral optic nerve crush followed by injection of MSC or the vehicle into the vitreous body. Before they were injected, MSC were labeled with a fluorescent dye or with superparamagnetic iron oxide nanoparticles, ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2014 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Dino Roberto Soares De Lorenzi, Edmund Chada Baracat, Bruno Saciloto, Irineu Padilha,
OBJETIVO: Avaliar a qualidade de vida de mulheres na pós-menopausa. MÉTODOS: Estudo transversal de 323 mulheres pós-menopáusicas com idade entre 45 e 60 anos atendidas em um serviço universitário de atenção ao climatério entre junho e outubro de 2002. A qualidade de vida foi avaliada através do Women's Health Questionnaire. Na análise estatística, utilizou-se o teste t de Student e a análise de variância, seguidos de regressão linear múltipla. RESULTADOS: A qualidade de vida se mostrou comprometida ...
Tópico(s): Women's cancer prevention and management
2006 - Brazilian Medical Association | Revista da Associação Médica Brasileira
Produção Nacional
Revisado por pares
Dino Roberto Soares De Lorenzi, Claudia Danelon, Bruno Saciloto, Irineu Padilha,
OBJETIVO: identificar fatores indicadores da sintomatologia climatérica. PACIENTES E MÉTODOS: estudo transversal de 254 mulheres pós-menopáusicas com idade entre 45 e 60 anos atendidas em Ambulatório de Climatério entre junho e outubro de 2002. Foram excluídas mulheres histerectomizadas ou sob terapia hormonal. As atitudes sobre a menopausa foram avaliadas por meio de instrumento construído a partir da adaptação de um questionário, constituindo-se de 11 questões referentes a atitudes positivas (vantagens) ...
Tópico(s): Menopause: Health Impacts and Treatments
2005 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Juscélia Padilha, Ildegardis Bertol, Bruno Afonso Magro, Bárbara Bagio, Juliana Marioti, Júlio César Ramos,
ABSTRACT Soil tillage influences the development of forests planted in the initial phase, which affects some hydrological processes and water erosion. The objective of this study was to quantify the water losses (WL) and soil losses (SL) by water erosion, between the second and third years of eucalyptus (Eucalyptus benthamii) crop, in an experiment located in southern Brazil, on a Humic Dystrudept. Was study three soil tillage treatments: i) subsoiling in downslope direction (SD); ii) subsoiling in ...
Tópico(s): Hydrology and Sediment Transport Processes
2018 - Sociedade de Investigações Florestais | Revista Árvore
Produção Nacional
Bruno Gomes Padilha, Paulo Victor Vasconcelos de Albuquerque, Fernando de Araújo Pedrosa,
INTRODUCTION: Cutaneous leishmaniasis is a severe public health problem in Brazil, particularly in Alagoas State.It is one of the parasitic diseases that affect skin and mucosae, and is closely related to environmental, behavioral and demographic changes.METHODS: The epidemiological indicators of the manual for surveillance of American integumentary leishmaniasis were calculated and evaluated on a ten-year historical series and their data were collected by the Department of Epidemiological Surveillance ...
Tópico(s): Research on Leishmaniasis Studies
2010 - | Revista Pan-Amazônica de Saúde
Produção Nacional
Revisado por pares
F.L.N. Aguiar, Franciele Osmarini Lunardi, Laritza Ferreira de Lima, Rebeca Magalhães Pedrosa Rocha, Jamily Bezerra Bruno, D.M. Magalhães-Padilha, Francielli Weber Santos Cibin, Diana Célia Sousa Nunes‐Pinheiro, M.O. Gastal, Ana Paula Ribeiro Rodrigues, G. A. Apgar, E.L. Gastal, J.R. Figueiredo,
This study investigated the effect of adding different concentrations of bovine recombinant follicle-stimulating hormone on the IVC of equine preantral follicles enclosed in ovarian tissue fragments. Randomized ovarian fragments were fixed immediately (fresh noncultured control) or cultured for 1 or 7 days in α-MEM(+) supplemented with 0, 10, 50, and 100 ng/mL FSH and subsequently analyzed by classical histology. Culture media collected on Day 1 or Day 7 and were analyzed for steroids (estradiol and ...
Tópico(s): Ovarian function and disorders
2015 - Elsevier BV | Theriogenology
Produção Nacional
Revisado por pares
F.L.N. Aguiar, Franciele Osmarini Lunardi, Laritza Ferreira de Lima, Rebeca Magalhães Pedrosa Rocha, Jamily Bezerra Bruno, D.M. Magalhães-Padilha, Francielli Weber Santos Cibin, Ana Paula Ribeiro Rodrigues, M.O. Gastal, E.L. Gastal, J.R. Figueiredo,
This study investigated the effect of insulin concentration on the in vitro culture of equine preantral follicles enclosed in ovarian tissue. Ovarian tissue samples were immediately fixed (noncultured control) or cultured for 1 or 7 days in α-MEM+ supplemented with 0 ng/mL, 10 ng/mL, or 10 μg/mL insulin. Ovarian tissues were processed and analyzed by classical histology. Culture medium samples were collected after 1 and 7 days of culture for steroid and reactive oxygen species (ROS) analyses. The ...
Tópico(s): Sperm and Testicular Function
2015 - Elsevier BV | Theriogenology
Produção Nacional
Revisado por pares
Bruno Vilhena Adorno, Antônio Padilha Lanari Bó, Philippe Fraisse,
SUMMARY This paper presents a novel approach for the description of physical human-robot interaction (pHRI) tasks that involve two-arm coordination, and where tasks are described by the relative pose between the human hand and the robot hand. We develop a unified kinematic model that takes into account the human-robot system from a holistic point of view, and we also propose a kinematic control strategy for pHRI that comprises different levels of shared autonomy. Since the kinematic model takes into ...
Tópico(s): EEG and Brain-Computer Interfaces
2014 - Cambridge University Press | Robotica
Produção Nacional
Revisado por pares
Bruno Padilha, Rafael Liberato Roberto, André Luís Schwerz, Calton Pu, João Eduardo Ferreira,
Tópico(s): Petri Nets in System Modeling
2018 - Springer Science+Business Media | Lecture notes in computer science
Produção Nacional
Revisado por pares
Sofia Mendes Sieczkowska, Alisson Padilha de Lima, Paul Swinton, Eimear Dolan, Hamilton Roschel, Bruno Gualano,
Health coaching has emerged as a potential supporting tool for health professionals to overcome behavioral barriers, but its efficacy in weight management remains unclear. We conducted a systematic review and meta-analysis to synthesize and evaluate the quality of evidence supporting the use of self-reported health coaching for weight loss. Seven electronic databases (PubMed, Web of Science, Scopus, Cochrane, Psyinfo, Virtual Health Library, and Scielo) were independently searched from inception ...
Tópico(s): Health Promotion and Cardiovascular Prevention
2020 - Elsevier BV | Advances in Nutrition
Produção Nacional
Revisado por pares
Bruno Silva Milagres, Amanda F. Padilha, Carlos Emmanuel Montandon, Renata Nascimento de Freitas, Richard de Campos Pacheco, David H. Walker, Marcelo B. Labruna, Cláudio Mafra, Márcio A. M. Galvão,
We investigated the humoral immune response against different species of Rickettsia in serum samples from small rodents collected in two areas of a silent focus for Brazilian spotted fever in the eastern region of Minas Gerais State, Brazil. Sera samples were analyzed by indirect immunofluorescence assay using antigens from Rickettsia species of the spotted fever, ancestral, and transition groups. Titers ≥ 1:64 were considered positive. In Santa Cruz do Escalvado, 94% (30 of 32) of the samples collected ...
Tópico(s): Mosquito-borne diseases and control
2013 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Gustavo de Albuquerque Cavalcanti, Felipe Dias Leal, Bruno Carius Garrido, Monica Costa Padilha, Francisco Radler de Aquino Neto,
The use of "nutritional supplements" containing unapproved substances has become a regular practice in amateur and professional athletes. This represents a dangerous habit for their health once no data about toxicological or pharmacological effects of these supplements are available. Most of them are freely commercialized online and any person can buy them without medical surveillance. Usually, the steroids intentionally added to the "nutritional supplements" are testosterone analogues with some structural ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2012 - Elsevier BV | Steroids
Produção Nacional
Revisado por pares
Bruno Silva Milagres, Amanda F. Padilha, Rafael Mazioli Barcelos, Gabriel Guimarães Gomes, Carlos Emmanuel Montandon, Dárlen Crísthiê Hermelinda Pena, Fernanda A. Nieri-Bastos, Iara Silveira, Richard de Campos Pacheco, Marcelo B. Labruna, Donald H. Bouyer, Renata Nascimento de Freitas, David H. Walker, Cláudio Mafra, Márcio A. M. Galvao,
The aim of this study was to understand the current epidemiology of rickettsial diseases in two rickettsial-endemic regions in Brazil. In the municipalities of Pingo D'Agua and Santa Cruz do Escalvado, among serum samples obtained from horses and dogs, reactivity by immunofluorescent assay against spotted fever group rickettsiae was verified. In some serum samples from opossums ( Didelphis aurita ) captured in Santa Cruz do Escalvado, serologic response against rickettsiae was also verified. Polymerase ...
Tópico(s): Vector-Borne Animal Diseases
2010 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Amanda Veiga Sardeli, Arthur Fernandes Gáspari, Wellington Martins dos Santos, Daisa Fabiele Godoi Moraes, Victor Bueno Gadelha, Lucas do Carmo Santos, Marina Lívia Venturini Ferreira, Simara Maria de J. Prudêncio, Ivan Luiz Padilha Bonfante, Bruno Rodrigues, Cláudia Regina Cavaglieri, Bo Fernhall, Mara Patrícia Traina Chacon‐Mikahil,
Aims: This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Methods: The patients will be randomized to a control or combined training group interventions (aerobic and resistance exercise), with monthly assessments in four months. Although, the changes in ...
Tópico(s): Stress Responses and Cortisol
2018 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Motriz Revista de Educação Física
Produção Nacional
Revisado por pares
André Luis Selmi, João Guilherme Padilha Filho, Bruno Testoni Lins, Guilherme Maia Mendes, Gisleine Cristina Eimantas,
Avaliaram-se as alterações clínicas e radiográficas em nove cães adultos, após a transecção do ligamento cruzado cranial (LCCr) seguida da substituição ligamentar por retalho de fáscia lata, associada ou não à incisuroplastia troclear (ITR). O joelho direito (GI) foi submetido à ITR e posterior estabilização articular, e o esquerdo somente à substituição ligamentar (GC). Os animais foram avaliados nos períodos pré-operatório, pós-operatório (po) imediato e aos 30, 90 e 180 dias de po, período coincidente ...
Tópico(s): Veterinary Orthopedics and Neurology
2007 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Produção Nacional
Revisado por pares
Fernanda Cristina P. Rocha e Silva, Bruno Augusto Cabral Roque, Nathália Maria Padilha da Rocha e Silva, Raquel D. Rufino, Juliana M. Luna, Valdemir Alexandre dos Santos, İbrahim M. Banat, Leonie Asfora Sarubbo,
Oil sludge or waste generated in transport, storage or refining forms highly stable mixtures due to the presence and additives with surfactant properties and water forming complex emulsions. Thus, demulsification is necessary to separate this residual oil from the aqueous phase for oil processing and water treatment/disposal. Most used chemical demulsifiers, although effective, are environmental contaminants and do not meet the desired levels of biodegradation. We investigated the application of ...
Tópico(s): Environmental Chemistry and Analysis
2017 - Springer Nature | AMB Express
Produção Nacional
Revisado por pares
Alisson Padilha de Lima, Tânia Rosane Bertoldo Benedetti, Cassiano Ricardo Rech, Fabrício Bruno Cardoso, Marilene Rodrigues Portella,
The aim of this study was to identify the factors associated with knowledge and attitude towards type 2 diabetes mellitus among older adults with the disease. A cross-sectional population-based study was conducted on 204 older adults from the public healthcare network of Passo Fundo, RS. Sociodemographic data were collected and the DKN-A, ATT-19 and IPAQ were used for the assessment of diabetes knowledge, psychological attitudes towards diabetes and physical activity, respectively. Logistic regression ...
Tópico(s): Health and Lifestyle Studies
2020 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
José Carlos de Lima Júnior, Gabriela Freitas Pereira de Souza, Alexandre Moura‐Assis, Rodrigo S. Gaspar, Joana M. Gaspar, Andréa L. Rocha, Danilo Lopes Ferrucci, Tanes Lima, Sheila C. Victório, Ivan Luiz Padilha Bonfante, Cláudia Regina Cavaglieri, José Carlos Pareja, S.Q. Brunetto, Celso Darío Ramos, Bruno Geloneze, Marcelo A. Mori, Leonardo R. Silveira, Gesmar Rodrigues Silva Segundo, Eduardo R. Ropelle, Lı́cio A. Velloso,
Inflammation is the most relevant mechanism linking obesity with insulin-resistance and metabolic disease. It impacts the structure and function of tissues and organs involved in metabolism, such as the liver, pancreatic islets and the hypothalamus. Brown adipose tissue has emerged as an important component of whole body energy homeostasis, controlling caloric expenditure through the regulation of non-shivering thermogenesis. However, little is known about the impact of systemic inflammation on ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2018 - Elsevier BV | EBioMedicine
Produção Nacional
Revisado por pares
F.L.N. Aguiar, Franciele Osmarini Lunardi, Laritza Ferreira de Lima, Jamily Bezerra Bruno, Bênner Geraldo Alves, D.M. Magalhães-Padilha, Francielli Weber Santos Cibin, L. Berioni, G. A. Apgar, E.G. Lo Turco, E.L. Gastal, J.R. Figueiredo,
The effects of epidermal growth factor (EGF) concentrations (0, 10, 50, and 100 ng/ml) on in vitro culture (IVC) of equine preantral follicles were evaluated using histology, estradiol and reactive oxygen species (ROS) production and metabolomics. After IVC, the percentage of normal follicles was lower (P < 0.05) for all treatments when compared to non-cultured control. EGF 50 ng/ml treatment had more (P < 0.05) normal follicles at Day 7 of culture when compared with EGF 0 and 100 ng/ml. EGF 50 ng/ml had ...
Tópico(s): Ovarian function and disorders
2017 - Elsevier BV | Research in Veterinary Science
Produção Nacional
Revisado por pares
Artur Gouveia Rocha, R.C. Costa, Gláucia Oliveira Morato, Denise Granato Chung, J.G. Padilha-Filho, Bruno Watanabe Minto, Luís Gustavo Gosüen Gonçalves Dias,
ABSTRACT Twelve dogs with traumatic hip luxation were selected for surgical intervention with a modified iliofemoral suture technique using an anchor screw to substitute the passage of suture material through a perforated tunnel in the ilium. Six procedures were performed with non-absorbable suture and other six with absorbable suture materials. These cases were evaluated at 15, 30, 60, and 90 days after surgery by performing an ambulation analysis and palpation of the joint. In all cases, there ...
Tópico(s): Hip disorders and treatments
2020 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Produção Nacional
Artur Gouveia Rocha, N.M. Rosa-Ballaben, P. C. Moraes, J.G. Padilha Filho, Bruno Watanabe Minto,
As fraturas de mandíbula ocorrem com relativa frequência em gatos, sendo as separações da sínfise mentoniana a apresentação mais comum. Muitos procedimentos são propostos para a correção destas fraturas, cabendo ao cirurgião a escolha pelo melhor método. O presente estudo objetivou avaliar uma técnica não invasiva baseada na aplicação de um bloqueio labial com botões para tratamento das fraturas do corpo da mandíbula associadas à disjunção da sínfise mentoniana em gatos. F oram avaliados 5 animais ...
Tópico(s): Facial Trauma and Fracture Management
2013 - | Ars Veterinaria
Produção Nacional
Revisado por pares
Maria Carmo Pereira Nunes, Craig Sable, Bruno Ramos Nascimento, Emilly M. Lima, José Luiz Padilha da Silva, Adriana C Diamantino, Kaciane K.B. Oliveira, Emmy Okello, Twalib Aliku, Peter Lwabi, Enrico A. Colosimo, Antônio Luiz Pinho Ribeiro, Andrea Beaton,
Background: The 2012 World Heart Federation Criteria are the current gold standard for the diagnosis of latent rheumatic heart disease (RHD). Because data and experience using these criteria have grown, there is opportunity to simplify and develop outcome prediction tools. We aimed to develop a simple echocardiographic score applicable for RHD screening with potential to predict disease progression. Methods: This study included 3 cohorts used for score derivation (n=9501), score validation (n=7312), ...
Tópico(s): Cardiac Arrhythmias and Treatments
2019 - Lippincott Williams & Wilkins | Circulation Cardiovascular Imaging
Produção Nacional
Revisado por pares
Maria Carmo Pereira Nunes, Timothy C. Tan, Sammy Elmariah, Lucas Lodi‐Junqueira, Bruno Ramos Nascimento, Rodrigo do Lago, José Luiz Padilha da Silva, Rodrigo Citton Padilha dos Reis, Xin Zeng, Igor F. Palacios, Judy Hung, Robert A. Levine,
Objectives Rheumatic mitral stenosis (MS) is a progressive disease, and risk of death may persist despite relief of the obstruction. Net atrioventricular compliance (C n ) modulates the overall haemodynamic burden of the MS and may be useful in predicting cardiovascular death after percutaneous mitral valvuloplasty (PMV). Methods A total of 427 patients (mean age 50±16 years, 84% female) with severe MS undergoing PMV were enrolled. Doppler-derived C n was estimated at baseline using a previously validated equation. ...
Tópico(s): Cardiac pacing and defibrillation studies
2017 - BMJ | Heart
Produção Nacional
Revisado por pares
Qian Zhong, Bruno Vieira Humia, Alisha R. Punjabi, Francine Ferreira Padilha, Sandro R. P. da Rocha,
Oral inhalation (OI) of nano-chemotherapeutics holds great potentials in the treatment of lung cancers as it enables direct targeting of drugs to lung tissues, spatial and temporal control of drug release, and decrease in drug-associated systemic and local lung toxicity. Therefore, the design of chemistry of the nanocarriers and their OI formulations for chemotherapeutics delivery to the peripheral lungs and extrapulmonary tissues of relevance such as lymph nodes, may thus afford new opportunities ...
Tópico(s): Membrane Separation and Gas Transport
2017 - Elsevier BV | European Journal of Pharmaceutical Sciences
Produção Nacional
Revisado por pares
Gustavo de Albuquerque Cavalcanti, Bruno Carius Garrido, Felipe Dias Leal, Monica Costa Padilha, Monica Mazzarino, Xavier de la Torre, Francesco Botrè, Francisco Radler de Aquino Neto,
Exemestane is an irreversible aromatase inhibitor used for anticancer therapy. Unfortunately, this drug is also misused in sports to avoid some adverse effects caused by steroids administration. For this reason exemestane has been included in World Anti-Doping Agency prohibited list. Usually, doping control laboratories monitor prohibited substances through their metabolites, because parent compounds are readily metabolized. Thus metabolism studies of these substances are very important. Metabolism ...
Tópico(s): Hormonal and reproductive studies
2011 - Elsevier BV | The Journal of Steroid Biochemistry and Molecular Biology