Limpar
1.969 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marcos de Souza Queiroz, Leny Aparecida Delamuta,

... de nível superior do serviço de saúde Dr. Cândido Ferreira, em Campinas. Trata-se de uma instituição filantrópica ...

Tópico(s): Youth, Drugs, and Violence

2011 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gustavo Zambenedetti,

... a experiência desenvolvida no Serviço de Saúde Dr. Cândido Ferreira (SSCF), localizado no município de Campinas-SP. Apresenta ...

Tópico(s): Psychology and Mental Health

2009 - UNIVERSIDADE DE SÃO PAULO | Saúde e Sociedade

Artigo Acesso aberto Revisado por pares

Ferdinand Althammer, Ranjan K. Roy, Matthew K. Kirchner, Elba Campos‐Lira, Kathryn Whitley, Steven Davis, Juliana Montanez, Hildebrando Candido Ferreira‐Neto, Jessica Danh, Rafaela G. Feresin, Vinicia C. Biancardi, Usama Zafar, Marise B. Parent, Javier E. Stern,

Heart failure (HF) is a debilitating disease affecting >64 million people worldwide. In addition to impaired cardiovascular performance and associated systemic complications, most patients with HF suffer from depression and substantial cognitive decline. Although neuroinflammation and brain hypoperfusion occur in humans and rodents with HF, the underlying neuronal substrates, mechanisms, and their relative contribution to cognitive deficits in HF remains unknown.

Tópico(s): Vagus Nerve Stimulation Research

2023 - Lippincott Williams & Wilkins | Hypertension

Artigo Acesso aberto Revisado por pares

David Ahern, Zhichao Ai, Mark Ainsworth, Chris Allan, Alice Allcock, Brian Angus, M. Azim Ansari, Carolina V. Arancibia-Cárcamo, Dominik Aschenbrenner, Moustafa Attar, J. Kenneth Baillie, Eleanor Barnes, Rachael Bashford-Rogers, Archana Bashyal, Sally Beer, G. Berridge, Amy Beveridge, Sagida Bibi, Tihana Bicanic, Luke Blackwell, Paul Bowness, Andrew Brent, Andrew Brown, John Broxholme, David Buck, Katie L. Burnham, Helen M. Byrne, Susana Camara, Ivan Candido-Ferreira, Philip D. Charles, Wentao Chen, Yi‐Ling Chen, Amanda Y. Chong, Elizabeth Clutterbuck, Mark Coles, Christopher P. Conlon, Richard J. Cornall, Adam P. Cribbs, Fabiola Curion, Emma E. Davenport, Neil Davidson, Simon Davis, Calliope A. Dendrou, Julie Dequaire, Lea Dib, James Docker, Christina Dold, Tao Dong, Damien J. Downes, Hal Drakesmith, Susanna Dunachie, David A. Duncan, Chris Eijsbouts, Robert Esnouf, Alexis Espinosa, Rachel Etherington, Benjamin P. Fairfax, Rory Fairhead, Hai Fang, Shayan Fassih, Sally Felle, Maria Fernandez Mendoza, Ricardo Melo Ferreira, Román Fischer, Thomas Foord, Aden Forrow, John Frater, Anastasia Fries, Verónica Sánchez, Lucy C. Garner, Clementine Geeves, Dominique Georgiou, Leila Godfrey, Tanya Golubchik, Maria Gomez Vazquez, Angie Green, Hong Harper, Heather A. Harrington, Raphael Heilig, Svenja Hester, Jennifer Hill, Charles Hinds, Clare Hird, Ling‐Pei Ho, Renee S. Hoekzema, Benjamin Hollis, Jim R. Hughes, Paula Hutton, Matthew A. Jackson-Wood, Ashwin Jainarayanan, Anna James-Bott, Kathrin Jansen, Katie Jeffery, Elizabeth Jones, Luke Jostins, Georgina Kerr, David Kim, Paul Klenerman, Julian C. Knight, Vinod Kumar, Piyush Kumar Sharma, Prathiba Kurupati, Andrew Kwok, Angela Lee, Aline Linder, Teresa Lockett, Lorne Lonie, Maria Lopopolo, Martyna Lukoseviciute, Jian Luo, Spyridoula Marinou, Brian D. Marsden, Jose Martinez, Philippa C. Matthews, Michalina Mazurczyk, Simon J. McGowan, Stuart McKechnie, Adam J. Mead, Alexander J. Mentzer, Yuxin Mi, Claudia Monaco, Ruddy Montadon, Giorgio Napolitani, Isar Nassiri, Alex Novak, Darragh P. O’Brien, Daniel O’Connor, Denise O’Donnell, Graham S. Ogg, Lauren Overend, Inhye Park, Ian Pavord, Yanchun Peng, Frank Penkava, Mariana Pereira Pinho, Elena Perez, Andrew J. Pollard, Fiona Powrie, Bethan Psaila, T. Phuong Quan, Emmanouela Repapi, Santiago Revale, Laura Silva-Reyes, Jean-Baptiste Richard, Charlotte Rich-Griffin, Thomas Ritter, Christine S. Rollier, Matthew Rowland, Fabian Ruehle, Mariolina Salio, Stephen N. Sansom, Raphael Sanches Peres, Alberto Santos Delgado, Tatjana Sauka‐Spengler, Ron Schweßinger, Giuseppe Scozzafava, Gavin Screaton, Anna Seigal, Malcolm G. Semple, Martin J. Sergeant, Christina Simoglou Karali, David Sims, Donal Skelly, Hubert Slawinski, Alberto Sobrinodiaz, Nikolaos Sousos, Lizzie Stafford, Lisa Stockdale, Marie Strickland, Otto Sumray, Bo Sun, Chelsea Taylor, Stephen Taylor, A Taylor, Supat Thongjuea, Hannah Thraves, John A. Todd, Adriana Tomić, Orion Tong, Amy Trebes, Dominik Trzupek, Felicia Anna Tucci, Lance Turtle, Irina A. Udalova, Holm H. Uhlig, Erinke van Grinsven, Iolanda Vendrell, Marije K. Verheul, Alexandru-Ioan Voda, Guanlin Wang, Lihui Wang, Dapeng Wang, Peter Watkinson, Robert Watson, Michael Weinberger, Justin P. Whalley, Lorna Witty, Katherine Wray, Luzheng Xue, Hing‐Yuen Yeung, Zixi Yin, Rebecca Young, Jonathan Youngs, Ping Zhang, Yasemin-Xiomara Zurke,

Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete description of specific immune biomarkers. We present here a comprehensive multi-omic blood atlas for patients with varying COVID-19 severity in an integrated comparison with influenza and sepsis patients versus healthy volunteers. We identify immune signatures and correlates of host response. Hallmarks of disease severity involved cells, their inflammatory mediators and networks, including progenitor cells ...

Tópico(s): Long-Term Effects of COVID-19

2022 - Cell Press | Cell

Artigo

Christos P Kotanidis, Cheng Xie, Donna Maria Alexander, Jonathan Rodrigues, Katie L. Burnham, Alexander J. Mentzer, Daniel O’Connor, Julian C. Knight, Muhammad Siddique, Helen Lockstone, Sheena Thomas, Rafail A. Kotronias, Evangelos K. Oikonomou, Ileana Badi, Maria Lyasheva, Cheerag Shirodaria, Sheila Lumley, Bede Constantinides, Nicholas Sanderson, Gillian Rodger, Kevin Chau, Archie Lodge, Maria Tsakok, Fergus Gleeson, David Adlam, Praveen P. N. Rao, Das Indrajeet, Aparna Deshpande, Amrita Bajaj, Benjamin Hudson, Vivek Srivastava, Shakil Farid, George Krasopoulos, Rana Sayeed, Ling‐Pei Ho, Stefan Neubauer, David E. Newby, Keith M. Channon, John Deanfield, Charalambos Antoniades, David Ahern, Zhichao Ai, Mark Ainsworth, Chris Allan, Alice Allcock, Brian Angus, M. Azim Ansari, Carolina V. Arancibia-Cárcamo, Dominik Aschenbrenner, Moustafa Attar, J. Kenneth Baillie, Eleanor Barnes, Rachael Bashford-Rogers, Archana Bashyal, Sally Beer, G. Berridge, Amy Beveridge, Sagida Bibi, Tihana Bicanic, Luke Blackwell, Paul Bowness, Andrew Brent, Andrew Brown, John Broxholme, David Buck, Katie L. Burnham, Helen M. Byrne, Susana Camara, Ivan Candido-Ferreira, Philip D. Charles, Wentao Chen, Yi‐Ling Chen, Amanda Y. Chong, Elizabeth Clutterbuck, Mark Coles, Christopher P. Conlon, Richard J. Cornall, Adam P. Cribbs, Fabiola Curion, Emma E. Davenport, Neil C. Davidson, Simon Davis, Calliope A. Dendrou, Julie Dequaire, Lea Dib, James Docker, Christina Dold, Tao Dong, Damien J. Downes, Hal Drakesmith, Susanna Dunachie, David A. Duncan, Chris Eijsbouts, Robert Esnouf, Alexis Espinosa, Rachel Etherington, Benjamin P. Fairfax, Rory Fairhead, Hai Fang, Shayan Fassih, Sally Felle, Maria Fernandez Mendoza, Ricardo Melo Ferreira, Roman Fischer, Thomas Foord, Aden Forrow, John Frater, Anastasia Fries, Verónica Sánchez, Lucy C. Garner, Clementine Geeves, Dominique Georgiou, Leila Godfrey, Tanya Golubchik, Maria Gomez Vazquez, Angie Green, Hong Harper, Heather A. Harrington, Raphael Heilig, Svenja Hester, Jennifer Hill, Charles Hinds, Clare Hird, Ling‐Pei Ho, Renee S. Hoekzema, Benjamin Hollis, Jim R. Hughes, Paula Hutton, Matthew A. Jackson-Wood, Ashwin Jainarayanan, Anna James-Bott, Kathrin Jansen, Katie Jeffery, Elizabeth Jones, Luke Jostins, Georgina Kerr, David Kim, Paul Klenerman, Julian C. Knight, Vinod Kumar, Piyush Kumar Sharma, Prathiba Kurupati, Andrew Kwok, A.H.S. Lee, Aline Linder, Teresa Lockett, Lorne Lonie, Maria Lopopolo, Martyna Lukoseviciute, Jian Luo, Spyridoula Marinou, Brian D. Marsden, Jose Martinez, Philippa C. Matthews, Michalina Mazurczyk, Simon J. McGowan, Stuart McKechnie, Adam J. Mead, Alexander J. Mentzer, Yuxin Mi, Claudia Monaco, Ruddy Montadon, Giorgio Napolitani, Isar Nassiri, Alex Novak, Darragh P. O’Brien, Daniel O’Connor, Denise O’Donnell, Graham S. Ogg, Lauren Overend, Inhye Park, Ian Pavord, Yanchun Peng, Frank Penkava, Mariana Pereira Pinho, Elena Perez, Andrew J. Pollard, Fiona Powrie, Bethan Psaila, T. Phuong Quan, Emmanouela Repapi, Santiago Revale, Laura Silva-Reyes, Jean-Baptiste Richard, Charlotte Rich-Griffin, Thomas Ritter, Christine S. Rollier, Matthew Rowland, Fabian Ruehle, Mariolina Salio, Stephen N. Sansom, Raphael Sanches Peres, Alberto Santos, Tatjana Sauka‐Spengler, Ron Schweßinger, Giuseppe Scozzafava, Gavin Screaton, Anna Seigal, Malcolm G. Semple, Martin J. Sergeant, Christina Simoglou Karali, David Sims, Donal Skelly, Hubert Slawinski, Alberto Sobrinodiaz, Nikolaos Sousos, Lizzie Stafford, Lisa Stockdale, Marie Strickland, Otto Sumray, Bo Sun, Chelsea Taylor, Stephen Taylor, A Taylor, Supat Thongjuea, Hannah Thraves, John A. Todd, Adriana Tomić, Orion Tong, Amy Trebes, Dominik Trzupek, Felicia Anna Tucci, Lance Turtle, Irina A. Udalova, Holm H. Uhlig, Erinke van Grinsven, Iolanda Vendrell, Marije K. Verheul, Alexandru-Ioan Voda, Guanlin Wang, Lihui Wang, Dapeng Wang, Peter Watkinson, Robert Watson, Michael Weinberger, Justin P. Whalley, Lorna Witty, Katherine Wray, Luzheng Xue, Hing‐Yuen Yeung, Zixi Yin, Rebecca Young, Jonathan Youngs, Ping Zhang, Yasemin-Xiomara Zurke, Adrian Banning, Alexios S. Antonopoulos, Amrita Bajaj, Andrew Kelion, Aparna Deshpande, Attila Kardos, Benjamin Hudson, Bon–Kwon Koo, Cheerag Shirodaria, Cheng Xie, Christos P Kotanidis, Ciara Mahon, Colin Berry, David Adlam, David E. Newby, Derek Connolly, Diane Scaletta, Donna Maria Alexander, Ed Nicol, Elisa McAlindon, Evangelos K. Oikonomou, Francesca Pugliese, Gianluca Pontone, Giulia Benedetti, Guo‐Wei He, Henry West, Hidekazu Kondo, Imre Benedek, Intrajeet Das, John Deanfield, John Graby, John P. Greenwood, Jonathan Rodrigues, Junbo Ge, Keith M. Channon, Larissa Fabritz, Lijuan Fan, Lucy Kingham, Marco Guglielmo, Maria Lyasheva, Matthias Schmitt, Meinrad Beer, Michelle A. Anderson, Milind Y. Desai, Mohamed Marwan, Naohiko Takahashi, Nehal N. Mehta, Neng Dai, Nicholas Screaton, Nikant Sabharwal, Pál Maurovich‐Horvat,

Background Direct evaluation of vascular inflammation in patients with COVID-19 would facilitate more efficient trials of new treatments and identify patients at risk of long-term complications who might respond to treatment.We aimed to develop a novel artificial intelligence (AI)-assisted image analysis platform that quantifies cytokine-driven vascular inflammation from routine CT angiograms, and sought to validate its prognostic value in COVID-19. MethodsFor this prospective outcomes validation ...

Elsevier BV

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ana Paula, Aline Graziela Deneka Carletto, Daniele Lopes, Joabe Candido Ferreira, Nelsi Salete Tonini, Sara Priscila Carvalho Trecossi,

ABSTRACT Objective: To understand the reactions and feelings of professionals in the frontline of care for inpatients with suspected COVID-19. Method: Qualitative approach study with 19 health team professionals from a teaching hospital located in the hinterland of the state of Paraná. Data were collected in March and April 2020. For data analysis, content analysis was used. Results: Of all professionals, 89.5% were female, 57.8% were between 20 and 30 years old. The following emotions and feelings ...

Tópico(s): Healthcare during COVID-19 Pandemic

2021 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | Revista gaúcha de enfermagem

Artigo Acesso aberto Brasil Produção Nacional

Lize Zanchetin Hosoume, Joabe Candido Ferreira, Gisele Andrade Menolli, Natália Marciano de Araújo Ferreira, Mara Cristina Nishikawa Yagi, Crysthianne Cônsolo de Almeida Baricati, Maria Clara Giorio Dutra Kreling, Márcia Eiko Karino,

INTRODUÇÃO: Os acidentes de trabalho (AT) são eventos adversos que podem ocorrer durante o exercício laboral quando a serviço da empresa, provocando lesão corporal, perturbação funcional, de caráter temporário ou permanente ou até mesmo a morte do segurado. Podem ser classificados como acidente de trabalho típico, de trajeto ou por doenças ocupacionais. METODOLOGIA: Trata- se de uma pesquisa de abordagem quantitativo, descritivo por meio de análise documental, retrospectivo de fichas de investigação ...

Tópico(s): Occupational Health and Safety in Workplaces

2021 - Brazilian Journal of Development | Brazilian Journal of Health Review

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Mariana Cândido Ferreira, Luciana Patrícia Fernandes Abbade, Sílvia Cristina Mangini Bocchi, Hélio Amante Miot, Paulo José Fortes Villas Bôas, Heloísa Cristina Quatrini Carvalho Passos Guimarães,

ABSTRACT Objective: To determine the prevalence and risk factors for incontinence-associated dermatitis in the elderly. Method: Cross-sectional exploratory study carried out in public hospitals. The dermatitis prevalence and associations were obtained by calculating the ratio. The effect dimension was estimated by the odds ratio with a 95% confidence interval and statistical significance p <0.05. Results: 138 elderly people were included, with an average age of 77.2 years old (± 9.3); 69 (50%) had combined ...

Tópico(s): Skin Protection and Aging

2020 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem

Artigo Acesso aberto Revisado por pares

Ferdinand Althammer, Hildebrando Candido Ferreira‐Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Anne Z. Murphy, Daniel N. Cox, Javier E. Stern,

Abstract Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, depression, and anxiety. While neuroinflammation in the hypothalamic paraventricular nucleus contributes to autonomic and cardiovascular dysregulation in heart failure, mechanisms underlying cognitive and mood disorders in this disease remain elusive. ...

Tópico(s): Neuroendocrine regulation and behavior

2020 - BioMed Central | Journal of Neuroinflammation

Artigo Acesso aberto Revisado por pares

Dorit Hockman, Vanessa Chong-Morrison, Stephen A. Green, Daria Gavriouchkina, Ivan Candido-Ferreira, Irving T. C. Ling, Ruth M. Williams, Chris T. Amemiya, Jeramiah J. Smith, Marianne Bronner‐Fraser, Tatjana Sauka‐Spengler,

The neural crest (NC) is an embryonic cell population that contributes to key vertebrate-specific features including the craniofacial skeleton and peripheral nervous system. Here we examine the transcriptional and epigenomic profiles of NC cells in the sea lamprey, in order to gain insight into the ancestral state of the NC gene regulatory network (GRN). Transcriptome analyses identify clusters of co-regulated genes during NC specification and migration that show high conservation across vertebrates ...

Tópico(s): Cancer-related molecular mechanisms research

2019 - Nature Portfolio | Nature Communications

Artigo Acesso aberto Revisado por pares

Ruth M. Williams, Ivan Candido-Ferreira, Emmanouela Repapi, Daria Gavriouchkina, Upeka Senanayake, Irving T. C. Ling, Jelena Telenius, Stephen Taylor, Jim R. Hughes, Tatjana Sauka‐Spengler,

Highlights•Profiling chromatin dynamics uncovers complete repertoire of neural crest (NC) enhancers•NC super-enhancers act additively to sustain network robustness•Enhancer clustering reveals early split between neural-NC and canonical NC programs•Global construction of cranial NC gene regulatory networkSummaryPrecise control of developmental processes is encoded in the genome in the form of gene regulatory networks (GRNs). Such multi-factorial systems are difficult to decode in vertebrates owing ...

Tópico(s): RNA Research and Splicing

2019 - Elsevier BV | Developmental Cell

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

W. V. Andrade Júnior, Cândido Ferreira de Oliveira Neto, Benedito Gomes dos Santos Filho, Cristine Bastos do Amarante, E. D. Cruz, Ricardo Shigueru Okumura, Antônio Vinícius Corrêa Barbosa, Diana Jhulia Palheta de Sousa, Jéssica Suellen Silva Teixeira, Anderson de Santana Botelho,

The steady increase in cadmium (Cd) levels in the environment from anthropogenic actions has contributed to environmental degradation. Virola surinamensis is a forest species that has desirable characteristics such as deep and dense roots, relatively rapid growth and high biomass production to remedy contaminated environments by Cd. The aim of this study was to assess the physiological responses and the phytoextraction and tolerance capacity of young plants of V. surinamensis submitted to Cd concentrations. ...

Tópico(s): Photosynthetic Processes and Mechanisms

2019 - Oxford University Press | AoB Plants

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Tabata Mariz Bohlen, Marina A. Silveira, Daniella do Carmo Buonfiglio, Hildebrando Candido Ferreira‐Neto, José Cipolla‐Neto, José Donato, Renata Frazão,

The reproduction of seasonal breeders is modulated by exposure to light in an interval of 24 h defined as photoperiod. The interruption of reproductive functions in seasonally breeding rodents is accompanied by the suppression of the Kiss1 gene expression, which is known to be essential for reproduction. In non-seasonal male rodents, such as rats and mice, short-day photoperiod (SP) conditions or exogenous melatonin treatment also have anti-gonadotropic effects; however, whether photoperiod is able ...

Tópico(s): Ovarian function and disorders

2018 - Frontiers Media | Frontiers in Endocrinology

Artigo Brasil Produção Nacional Revisado por pares

Susana Silva Conceição, Cândido Ferreira de Oliveira Neto, Elton Camelo Marques, Antônio Vinícius Corrêa Barbosa, Jessivaldo Rodrigues Galvão, Tamires Borges de Oliveira, Ricardo Shigueru Okumura, Jéssica Taynara da Silva Martins, Thays Corrêa Costa, Enéas Gomes‐Filho,

Sunflower (Helianthus annuus L.) is an important oilseed crop with clear sensibility to salt stress. In this study, we evaluated silicon (Si) effect on the nitrogen metabolism and antioxidant enzyme activity in sunflower plants subjected to salinity. A 4 × 4 factorial arrangement of treatments in a completely randomized design with four replicates was used, consisting of four concentrations of Si (0.0; 1.0; 1.5; and 2.0 mM) and four concentrations of NaCl (0; 50; 100; and 150 mM) in the nutrient solution. ...

Tópico(s): Geochemistry and Elemental Analysis

2018 - Taylor & Francis | Archives of Agronomy and Soil Science

Artigo Acesso aberto Revisado por pares

Hildebrando Candido Ferreira‐Neto, Vinicia C. Biancardi, Javier E. Stern,

Key points Small conductance Ca 2+ ‐activated K + (SK) channels play an important role in regulating the excitability of magnocellular neurosecretory cells (MNCs). Although an increased SK channel function contributes to adaptive physiological responses, it remains unknown whether changes in SK channel function/expression contribute to exacerbated MNC activity under disease conditions. We show that the input–output function of MNCs in heart failure (HF) rats is enhanced. Moreover, the SK channel blocker ...

Tópico(s): Neuroscience of respiration and sleep

2017 - Wiley | The Journal of Physiology

Artigo Brasil Produção Nacional Revisado por pares

Maria Fernanda Cury Rodrigues, Fabiano Cândido Ferreira, Natália Santanielo Silva-Magosso, Marina Rodrigues Barbosa, Markus Vinícius Campos Souza, Mateus Moraes Domingos, Gustavo Henrique Rigo Canevazzi, Uliana Sbeguen Stotzer, Sabrina Messa Peviani, Fábio Santos Lira, Heloísa Sobreiro Selistre-de-Araújo, Sérgio Eduardo de Andrade Perez,

Estrogen deficiency is directly related to central obesity and low-grade inflammation. Hormonal replacement and exercise training are both able to decrease fat accumulation and inflammation in postmenopausal women. However, the efficiency of resistance training (RT) and estrogen replacement (ER) in minimizing adiposity and inflammation in the visceral adipose tissue (VAT) of ovariectomized (OVX) rats has not yet been elucidated. In this study, Sprague–Dawley rats were divided into the following 6 groups: ...

Tópico(s): Adipose Tissue and Metabolism

2017 - NRC Research Press | Applied Physiology Nutrition and Metabolism

Artigo Brasil Produção Nacional Revisado por pares

Jaqueline Basílio Lupi, Daniela Cristina Carvalho de Abreu, Mariana Cândido Ferreira, Renê Donizeti Ribeiro de Oliveira, Thaís Cristina Chaves,

Purpose: This study aimed to culturally adapt and validate the Revised Fibromyalgia Impact Questionnaire (FIQR) to Brazilian Portuguese, by the use of analysis of internal consistency, reliability, and construct and structural validity.Method: A total of 100 female patients with fibromyalgia participated in the validation process of the Brazilian Portuguese version of the FIQR (FIQR-Br).The intraclass correlation coefficient (ICC) was used for statistical analysis of reliability (test–retest), Cronbach' ...

Tópico(s): Occupational Health and Performance

2016 - Informa | Disability and Rehabilitation

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Caio Akira Miyai, Fábio H. C. Sanches, Cândido Ferreira Pinho-Neto, Rodrigo Egydio Barreto,

Several fish species exhibit antipredator responses when exposed to chemicals which indicate risk of predation. One such substance is the scent of a predator (a kairomone) that may induce defensive responses in a potential prey. In the present study, we show that chemical cues (odour) from predator fish induce antipredator and stress responses in Nile tilapia. When exposed to predator odour, Nile tilapia decreased activity and increased ventilation rate (VR), but no increase in plasma levels of cortisol ...

Tópico(s): Aquaculture disease management and microbiota

2016 - Elsevier BV | Physiology & Behavior

Artigo Brasil Produção Nacional Revisado por pares

Fábio H. C. Sanches, Caio Akira Miyai, Cândido Ferreira Pinho-Neto, Rodrigo Egydio Barreto,

In predator–prey encounters between fish in which there is physical trauma to the epidermis of the prey, some species release chemical alarm cues into the water. Fish of the same species may perceive these cues and display antipredator behavior. Physiological adjustments may also be needed to deal with this adverse situation. To date, little attention has been devoted to the physiological adjustments that may co-occur with defensive responses. We have characterized the alarm cue-induced antipredator ...

Tópico(s): Physiological and biochemical adaptations

2015 - Elsevier BV | Physiology & Behavior

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Natália Ribeiro, Helena do Nascimento Panizza, Karoline Martins dos Santos, Hildebrando Candido Ferreira‐Neto, Vagner Roberto Antunes,

A high-salt diet can lead to hydromineral imbalance and increases in plasma sodium and osmolality. It is recognized as one of the major contributing factors for cardiovascular diseases such as hypertension. The paraventricular nucleus (PVN) plays a pivotal role in osmotically driven sympathoexcitation and high blood pressure, the precise mechanisms of which are not fully understood. Recent evidence indicates that AVP released from magnocellular neurons might be involved in this process. Using a combination ...

Tópico(s): Circadian rhythm and melatonin

2015 - American Physiological Society | AJP Regulatory Integrative and Comparative Physiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Hildebrando Candido Ferreira‐Neto, Vagner Roberto Antunes, Javier E. Stern,

We have previously shown that ATP within the paraventricular nucleus (PVN) induces an increase in sympathetic activity, an effect attenuated by the antagonism of P2 and/or glutamatergic receptors. Here, we evaluated precise cellular mechanisms underlying the ATP-glutamate interaction in the PVN and assessed whether this receptor coupling contributed to osmotically driven sympathetic PVN neuronal activity. Whole-cell patch-clamp recordings obtained from PVN-rostral ventrolateral medulla neurons showed ...

Tópico(s): Neuroendocrine regulation and behavior

2015 - American Physiological Society | Journal of Neurophysiology

Artigo Revisado por pares

José H. Teixeira, Patrícia Silva, Juliana Faria, Ivan Candido-Ferreira, Patrícia Duarte, Leonor Delgado, Odília Queirós, Roxana Moreira, Joana Barbosa, Carlos Lopes, Barbas do Amaral, Luı́s Monteiro, Hassan Bousbaa,

BubR1 and Mad2 are central components of the mitotic checkpoint complex that inhibits anaphase onset until all chromosomes are correctly aligned at the metaphase plate. We propose to analyse the combined expression of BubR1 and Mad2 and assess its significance to oral squamous cell carcinoma (OSCC) diagnosis and prognosis.BubR1 and Mad2 expression was assessed by real-time PCR in OSCC cell lines and in normal human oral keratinocytes, and by immunohistochemistry in 65 patients with OSCC. The results ...

Tópico(s): Epigenetics and DNA Methylation

2015 - Wiley | Oral Diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Mariana Cândido Ferreira, Débora Bevilaqua‐Grossi, Fabíola Dach, José Geraldo Speciali, Maria Cláudia Gonçalves, Thaís Cristina Chaves,

Migraine and temporomandibular disorders (TMDs) are reported to be associated. However, there are no reports on the association among migraines, TMDs and changes in body posture.To assess changes in body posture in women suffering migraines with or without TMD compared with a control group.Sixty-six women with a mean age of 18 to 45 years participated in this study. The groups were composed of 22 volunteers with migraine and TMD (MTMD), 22 volunteers with migraines without TMD (MG) and 22 women in ...

Tópico(s): Oropharyngeal Anatomy and Pathologies

2014 - Elsevier BV | Brazilian Journal of Physical Therapy

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Fernanda Cury Rodrigues, Uliana Sbeguen Stotzer, Mateus Moraes Domingos, Rafael Deminice, Gilberto Eiji Shiguemoto, Luciane Magri Tomaz, Nuno Manuel Frade de Sousa, Fabiano Cândido Ferreira, Richard Diego Leite, Heloísa Sobreiro Selistre-de-Araújo, Alceu Afonso Jordão-Júnior, Vilmar Baldissera, Sérgio Eduardo de Andrade Perez,

OBJECTIVE:The objective of this study was to assess the effects of resistance training on oxidative stress markers in the livers of ovariectomized rats.METHOD: Adult Sprague-Dawley rats were divided into the following four groups (n = 8 per group): shamoperated sedentary, ovariectomized sedentary, sham-operated resistance training, and ovariectomized resistance training.During the resistance training period, the animals climbed a 1.1-m vertical ladder with weights attached to their tails; the sessions ...

Tópico(s): Vitamin C and Antioxidants Research

2013 - Elsevier BV | Clinics

Artigo Brasil Produção Nacional Revisado por pares

Camila Sobral Torrezani, Cândido Ferreira Pinho-Neto, Caio Akira Miyai, Fábio H. C. Sanches, Rodrigo Egydio Barreto,

Environmental enrichment seeks to improve the behavior of captive animals. Few studies have developed enrichment strategies for fish, particularly for use in aquaculture. Environmental enrichment for territorial and aggressive animals has the potential to increase both the amount of defensible resources and the value of a disputed territory which can increase the level of aggression. This study evaluated this hypothesis for the redbreast tilapia, Tilapia rendaIli. We used a short-term approach for ...

Tópico(s): Animal Behavior and Reproduction

2013 - Taylor & Francis | Marine and Freshwater Behaviour and Physiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ademir Aparecido Constantino, Dario Landa-Silva, Everton Luiz de Melo, Candido Ferreira Xavier de Mendonça, Douglas Baroni Rizzato, Wesley Romão,

This paper tackles a Nurse Scheduling Problem which consists of generating work schedules for a set of nurses while considering their shift preferences and other requirements. The objective is to maximize the satisfaction of nurses' preferences and minimize the violation of soft constraints. This paper presents a new deterministic heuristic algorithm, called MAPA (multi-assignment problem-based algorithm), which is based on successive resolutions of the assignment problem. The algorithm has two phases: ...

Tópico(s): Constraint Satisfaction and Optimization

2013 - Springer Science+Business Media | Annals of Operations Research

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gabriela Ayroza, Ivan Candido-Ferreira, Raphael Santa Rosa Sayegh, Alexandre K. Tashima, Pedro Ismael da Silva,

The aim of this study was to screen the venom of the theraposid spider Avicularia juruensis for the identification of antimicrobial peptides which could be further used as prototypes for drug development. Eleven antimicrobial peptides, named juruentoxins, with molecular weight ranging from 3.5 to 4.5kDa, were identified by mass spectrometry after the soluble venom was separated by high performance liquid chromatography. Juruentoxins have a putative inhibitory cystine knot motif, generally found ...

Tópico(s): Biochemical and Structural Characterization

2012 - Frontiers Media | Frontiers in Microbiology