Produção Nacional
Revisado por pares
Cícero Cláudio Dias Gomes, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Gerson Oliveira Penna,
FUNDAMENTOS: A hanseníase permanece sério problema de saúde pública mundial. O conhecimento das características epidemiológicas da doença é importante ferramenta para o controle da endemia. OBJETIVO: Descrever as características clínicas e epidemiológicas dos pacientes diagnosticados com hanseníase no ano de 2004 em um centro de referência da Região Nordeste do Brasil. MÉTODO: Foram avaliados prontuários de pacientes que deram entrada no registro ativo do Centro de Dermatologia Dona Libânia, em ...
Tópico(s): Mycobacterium research and diagnosis
2005 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Carlos Bastidas‐Caldes, Daniel Romero-Álvarez, Victor Valdez-Vélez, Roberto D Morales, Andrés Montalvo-Hernández, Cícero Armídio Gomes-Dias, Manuel Calvopiña Hinojosa,
Purpose: Extended-spectrum beta-lactamase-producing (ESBL) Enterobacteriaceae, which includes Escherichia coli , has emerged as a global health threat. ESBL enzymes including CTX-M, TEM, and SHV are the most detected. Here, a systematic review was developed to assess the status of ESBLs in E. coli considering studies performed in the human, animal, food, and environmental realms in South America. Methods: Following PRISMA guidelines, a systematic review was performed using the PubMed database as a ...
Tópico(s): Vibrio bacteria research studies
2022 - Dove Medical Press | Infection and Drug Resistance
Produção Nacional
Revisado por pares
Adriana Medianeira Rossato, Muriel Primon-Barros, Lisiane da Luz Rocha, Keli Cristine Reiter, Cícero Armídio Gomes Dias, Pedro Alves d’Azevedo,
INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) is a common pathogen causing healthcare-associated infections. Owing to the restricted use of beta-lactams in MRSA infections, non-beta-lactam antimicrobials are required for treatment. However, MRSA can develop resistance mechanisms to non-beta-lactam antimicrobials, which reduces viable treatment options. Here, we evaluated the antimicrobial susceptibility and resistance genes of MRSA isolated from hospitalized patients in South Brazil. ...
Tópico(s): Antibiotic Resistance in Bacteria
2020 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Otávio Hallal Ferreira Raro, Ravena Maya Cardoso da Silva, Édison Moraes Rodrigues Filho, Teresa Sukiennik, Claudio Stadnik, Cícero Armídio Gomes Dias, Jesús Oteo, Marı́a Pérez-Vázquez,
Objectives: Carbapenemase-producing Klebsiella pneumoniae (CP-Kp) is a major cause of infections in transplanted patients and has been associated with high mortality rates in this group. There is a lack of information about the Brazilian structure population of CP-Kp isolated from transplanted patients. By whole-genome sequencing (WGS), we analyzed phylogeny, resistome, virulome of CP-Kp isolates and the structure of plasmids encoding bla KPC-2 and bla NDM-1 genes. Methods: One K. pneumoniae isolated ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2020 - Frontiers Media | Frontiers in Microbiology
Produção Nacional
Revisado por pares
Mariana Preussler Mott, Juliana Caierão, Gabriela Rosa da Cunha, M.M. Del Maschi, Kauana Pizzutti, Pedro Alves d’Azevedo, Cícero Armídio Gomes Dias,
Abstract Use of pneumococcal conjugate vaccines has caused emergence of non-vaccine serotypes. No Brazilian data specifically about serotype 19A are available. We aimed to evaluate the frequency of occurrence, susceptibility profile and molecular epidemiology of serotype 19A before and after vaccine introduction in Brazil. Pneumococcal identification was performed by the conventional method. Strain serotype was determined by multiplex polymerase chain reaction (PCR) and/or Quellung reaction. Resistance ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2019 - Cambridge University Press | Epidemiology and Infection
Produção Nacional
Revisado por pares
Aquino Albino Nhantumbo, Goitom Weldegebriel, Reggis Katsande, Linda de Gouveia, Charlotte Elizabeth Comé, Arlindo Zacarias Cuco, Vlademir Vicente Cantarelli, Cícero Armídio Gomes Dias, Juliana Caierão, Jason Mwenda Mathiu, Eduardo Samo Gudo,
Background Vaccination using the 10-valent conjugate vaccine (PCV-10) was introduced into the Extended Program on Immunization in Mozambique in March 2013, however its impact on pediatric pneumococcal meningitis is unknown. In this study, we assessed for the first time the impact of PCV10 on the burden of pneumococcal meningitis in children less than 5 years of age at the three largest hospitals in Mozambique. Method Between March 2013 and December 2015, a total of 744 cerebrospinal fluid (CSF) samples ...
Tópico(s): Respiratory viral infections research
2017 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Leandro Reus Rodrigues Perez, Cícero Armídio Gomes Dias,
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Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2016 - Cambridge University Press | Infection Control and Hospital Epidemiology
Produção Nacional
Revisado por pares
Cícero Rafael Barros Dias, Gauss M. Cordeiro, Morad Alizadeh, Pedro Rafael Diniz Marinho, Hemílio Fernandes Campos Coêlho,
We study general mathematical properties of a new class of continuous distributions with three extra shape parameters called the exponentiated Marshal-Olkin family of distributions. Further, we present some special models of the new class and investigate the shapes and derive explicit expressions for the ordinary and incomplete moments, quantile and generating functions and probability weighted moments. We discuss the estimation of the model parameters by maximum likelihood and show empirically ...
Tópico(s): Financial Risk and Volatility Modeling
2016 - Springer Nature | Journal of Statistical Distributions and Applications
Produção Nacional
Revisado por pares
Aquino Albino Nhantumbo, Vlademir Vicente Cantarelli, Juliana Caireão, Alcides Moniz Munguambe, Charlotte Elizabeth Comé, Gabriela do Carmo Pinto, Tomás F. Zimba, Inácio Mandomando, Cynthia Sema, Cícero Armídio Gomes Dias, Milton Ozório Moraes, Eduardo Samo Gudo,
Background In Sub-Saharan Africa, including Mozambique, acute bacterial meningitis (ABM) represents a main cause of childhood mortality. The burden of ABM is seriously underestimated because of the poor performance of culture sampling, the primary method of ABM surveillance in the region. Low quality cerebrospinal fluid (CSF) samples and frequent consumption of antibiotics prior to sample collection lead to a high rate of false-negative results. To our knowledge, this study is the first to determine ...
Tópico(s): Neonatal and Maternal Infections
2015 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Mariah Costa Carvalho de Resende, Juliana Caierão, Juliana Gil Prates, Gabriel Narváez, Cícero Armídio Gomes Dias, Pedro Alves d’Azevedo,
In Porto Alegre (South Brazil), since the first VRE isolation in 2000 until the middle of the last decade, the epidemiology of enterococcal infections presented the peculiarity that, as opposed to other regions of the country, almost all VRE were E. faecalis. The aim of this study was to investigate the microbiological and epidemiological characteristics of a VRE outbreak that occurred between August 2010 and September 2011 in Porto Alegre, South Brazil.Twenty-nine isolates from inpatients of Mãe ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2014 - Open Learning on Enteric Pathogens | The Journal of Infection in Developing Countries
Produção Nacional
Revisado por pares
Mariana Preussler Mott, Juliana Caierão, Gabriela Rosa da Cunha, Leandro Reus Rodrigues Perez, Roberto Matusiak, Kátia Ruschel Pilger de Oliveira, Pedro Alves d’Azevedo, Cícero Armídio Gomes Dias,
To evaluate the susceptibility patterns among Streptococcus pneumoniae recovered during the years 2010-2012 and to correlate these with serotypes.Pneumococci from invasive sites were serotyped by sequential multiplex PCR and/or Quellung reaction. Etest strips were used to determine the minimal inhibitory concentrations, and the Clinical and Laboratory Standards Institute (CLSI) guidelines were used for interpretation. Genetic determinants of macrolide resistance were assessed by PCR, and the occurrence ...
Tópico(s): Respiratory viral infections research
2014 - Elsevier BV | International Journal of Infectious Diseases
Produção Nacional
Revisado por pares
María Isabel Fischer, Cícero Armídio Gomes Dias, Aírton Tetelbom Stein, Nelson Guardiola Meinhardt, Isabela Heineck,
PURPOSE: To review the use of cefazolin in prophylaxis of surgical wound infection (SSI) in bariatric surgery (BS). METHODS: A systematic review was performed from October to November, 2013 using the following databases: The Cochrane Library, Medline, LILACS, and EMBASE. The inclusion criteria were randomized clinical trials and observational studies that were evaluated by two independent reviewers. RESULTS: Nine hundred and sixty one titles were recovered after preliminary analysis (title and abstract), ...
Tópico(s): Surgical Sutures and Adhesives
2014 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira
Produção Nacional
Revisado por pares
Juliana Caierão, Paulina A. Hawkins, Fernando Hayashi Sant’Anna, Gabriela Rosa da Cunha, Pedro Alves d’Azevedo, Lesley McGee, Cícero Armídio Gomes Dias,
To reduce the burden of pneumococcal diseases, different formulations of pneumococcal conjugate vaccines (PCV) have been introduced in many countries. In Brazil, PCV10 has been available since 2010. We aimed to analyze the serotype and genetic composition of invasive pneumococci from Brazil in pre- and post- vaccination periods (2007–2012). Antibiotic susceptibility was determined and genotypes of macrolide and fluoroquinolone resistance were characterized. The genotypes of isolates of the most frequent ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2014 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Vanusa G Dutra, Valéria MN Alves, André Nogueira Olendzki, Cícero Armídio Gomes Dias, Alessandra FA de Bastos, Gianni O Santos, Efigênia LT de Amorin, Meireille ÂB Sousa, Rosemary Santos, Patrícia C. S. Ribeiro, Cleuber Franco Fontes, Marco Andrey, K.C.S.F. Magalhães, Ana Albertina de Araújo, Lilian F Paffadore, Camila Marconi, Eddie Fernando Cândido Murta, Paulo César Fernandes, Maria SG Raddi, Penélope Saldanha Marinho, Rita BG Bornia, Jussara Kasuko Palmeiro, Libera Maria Dalla‐Costa, Tatiana Castro Abreu Pinto, Ana Caroline N. Botelho, Lúcia Martins Teixeira, Sérgio Eduardo Longo Fracalanzza,
Group B Streptococcus (GBS) remains a major cause of neonatal sepsis and is also associated with invasive and noninvasive infections in pregnant women and non-pregnant adults, elderly and patients with underlying medical conditions. Ten capsular serotypes have been recognized, and determination of their distribution within a specific population or geographical region is important as they are major targets for the development of vaccine strategies. We have evaluated the characteristics of GBS isolates ...
Tópico(s): Pneumonia and Respiratory Infections
2014 - BioMed Central | BMC Infectious Diseases
Produção Nacional
Revisado por pares
Manoel Wallace A. Ramos, Gauss M. Cordeiro, Pedro Rafael Diniz Marinho, Cícero Rafael Barros Dias, G. G. Hamedani,
The log-logistic distribution (also known as the Fisk distribution in economics) is widely used in survival analysis when the failure rate function presents a unimodal shape.In this paper, we introduce the Zografos-Balakrishnan log-logistic distribution, which contains the log-logistic distribution as a special model and has the four common shapes of the hazard hate function.We present some properties of the new distribution and estimate the model parameters by maximum likelihood.An application to ...
Tópico(s): Probability and Risk Models
2013 - Springer Nature | Journal of Statistical Theory and Applications
Produção Nacional
Revisado por pares
Tatiana Castro Abreu Pinto, Aline R. V. Souza, Sandrine E. C. M. de Pina, Natália Silva Costa, Armando A. Borges Neto, Felipe Piedade Gonçalves Neves, Vânia Lúcia Carreira Merquior, Cícero Armídio Gomes Dias, José Mauro Peralta, Lúcia Martins Teixeira,
Optochin (Opt) susceptibility is used largely for the identification of Streptococcus pneumoniae in diagnostic laboratories. Opt-resistant (Opt(r)) S. pneumoniae isolates have been reported, however, indicating the potential for misidentification of this important pathogen. Point mutations in the atpC gene have been associated with the emergence of Opt(r) S. pneumoniae, but data on the characterization of such atypical variants of S. pneumoniae are still limited. The present report describes the results ...
Tópico(s): Respiratory viral infections research
2013 - American Society for Microbiology | Journal of Clinical Microbiology
Produção Nacional
Revisado por pares
Rodrigo B. Silva, Marcelo Bourguignon, Cícero Rafael Barros Dias, Gauss M. Cordeiro,
We introduce a general method for obtaining more flexible new distributions by compounding the extended Weibull and power series distributions. The compounding procedure follows the same set-up carried out by Adamidis and Loukas (1998) and defines 68 new sub-models. The new class of generated distributions includes some well-known mixing distributions, such as the Weibull power series (Morais and Barreto-Souza, 2011) and exponential power series (Chahkandi and Ganjali, 2009) distributions. Some mathematical ...
Tópico(s): Hydrology and Drought Analysis
2012 - Elsevier BV | Computational Statistics & Data Analysis
Produção Nacional
Revisado por pares
Ana Paula Becker, Olinda Cabral dos Santos, Fernanda Marques da Silva Castrucci, Cícero Armídio Gomes Dias, Pedro Alves d’Azevedo,
SUMMARY Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection in hospitalized patients. Resistance is due to the acquisition of mecA gene located on the chromosomal element SCCmec and to date 12 types have been identified. Specific epidemic clones of MRSA have emerged with enhanced ability to spread within and among hospitals and to cross national boundaries. We studied 30 isolates from patients with MRSA infections at two hospitals in Porto Alegre city from April to December, ...
Tópico(s): Bacterial biofilms and quorum sensing
2011 - Cambridge University Press | Epidemiology and Infection
Produção Nacional
Revisado por pares
Fernanda Razera, S. Stefani, Renan Rangel Bonamigo, Gislaine Silveira Olm, Cícero Armídio Gomes Dias, Gabriel Narváez,
Staphylococcus aureus resistente à meticilina (MRSA), outrora isolado especificamente em ambientes hospitalares, vem sendo identificado como causador de infecções cutâneas em pacientes da comunidade. Neste artigo, é relatado um caso do sul do Brasil com furunculose por CA-MRSA. O microrganismo isolado foi submetido a exames de PCR para o gene mecA e para o gene que codifica a leucocidina de Panton-Valentine. Esses exames permitiram a identificação genotípica do CA-MRSA.
Tópico(s): Microbial Metabolism and Applications
2009 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Cícero Armídio Gomes Dias, Lúcia Martins Teixeira, Maria da Glória Carvalho, Bernard Beall,
Capsular serotype surveillance of clinical isolates of Streptococcus pneumoniae is essential for evaluation of the potential impact of introducing multivalent capsular serotype-based vaccines in Latin America. Here, a previously described sequential multiplex PCR method was revised for optimal targeting of prevalent serotypes in Latin America. The revised protocol successfully serotyped 139/147 pneumococci (94.6%) from Brazilian children, demonstrating a labour-efficient, accurate method requiring ...
Tópico(s): Bacterial Infections and Vaccines
2007 - Microbiology Society | Journal of Medical Microbiology
Produção Nacional
Revisado por pares
Apoena Aguiar Ribeiro, Amada Zambrana Coronado, M.C. Silva-Carvalho, Bernadete Teixeira Ferreira‐Carvalho, Cícero Armídio Gomes Dias, Ronaldo Rozenbaum, Pedro Fernandez Del Peloso, Cassiana da Costa Ferreira Leite, Lenise Arneiro Teixeira, Agnes Marie Sá Figueiredo,
Community-acquired infections by methicillin-resistant Staphylococcus aureus (CA-MRSA) in the absence of classic risk factors for MRSA diseases have been reported in different continents. In the article presented here, using molecular typing methods as pulsed-field gel electrophoresis, staphylococcal cassette chromosome mec typing, and multilocus sequence typing, we characterized CA-MRSA isolates from Rio Janeiro and Porto Alegre. The results indicated the presence of international CA-MRSA clones ...
Tópico(s): Bacterial biofilms and quorum sensing
2007 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Produção Nacional
Revisado por pares
Juliana Caierão, Laura Berquó, Cícero Armídio Gomes Dias, Pedro Alves d’Azevedo,
Methicillin-resistant Staphylococcus aureus (MRSA) is a serious nosocomial problem, globally distributed. Decolonization with mupirocin can be used to control its dissemination.To determine the incidence of mupirocin resistance among MRSA carriers from an intensive care unit.We obtained 2723 nasal swabs during 3 years. Resistance to methicillin and mupirocin were verified (agar diffusion and the E test) and confirmed by polymerase chain reaction (PCR) (mecA for methicillin; ileS-2 and mupA for mupirocin). ...
Tópico(s): Bacterial biofilms and quorum sensing
2006 - Elsevier BV | American Journal of Infection Control
Produção Nacional
Revisado por pares
Paulo Augusto Moreira Camargos, Gilberto Bueno Fischer, Helena Teresinha Mocelin, Cícero Armídio Gomes Dias, Raúl Ruvinsky,
Streptococcus pneumoniae (Strep. pneumoniae) is the main cause of bacterial pneumonia in children less than 5 years of age, with high mortality rates in developing countries. In 1993, the Regional System for Vaccines Group (SIREVA) of the pan-American Health Organisation (PAHO) began a study involving six Latin American countries to identify serotypes and their representativity in the new conjugated vaccines, and to determine the degree of resistance to penicillin. Serotypes 14 (highest resistance level), ...
Tópico(s): Bacterial Infections and Vaccines
2006 - Elsevier BV | Paediatric Respiratory Reviews
Produção Nacional
Revisado por pares
Alexandre Prehn Zavascki, Leandro Genehr Fritscher, Silvana Vargas Superti, Cícero Armídio Gomes Dias, L.V. Kroth, Moacir Alexandre Traesel, Ivan Carlos Ferreira Antonello, David Saitovitch,
ABSTRACT We describe a case of an adult organ recipient patient with a pulmonary cavitary lesion due to Neisseria lactamica , a harmless commensal organism that rarely causes human infection. To our knowledge, this is the first report of pulmonary disease caused by this organism and the second case of N. lactamica infection in an adult patient.
Tópico(s): Legionella and Acanthamoeba research
2006 - American Society for Microbiology | Journal of Clinical Microbiology
Produção Nacional
Revisado por pares
Juliana Caierão, Silvana Vargas Superti, Cícero Armídio Gomes Dias, Pedro Alves d’Azevedo,
Coagulase-negative staphylococci (CoNS) are an important cause of nosocomial bacteremia, specially in patients with indwelling devices or those submitted to invasive medical procedures. The identification of species and the accurate and rapid detection of methicillin resistance are directly dependent on the quality of the identification and susceptibility tests used, either manual or automated. The objective of this study was to evaluate the accuracy of two automated systems MicroScan and Vitek - in ...
Tópico(s): Bacterial biofilms and quorum sensing
2006 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Pedro Alves d’Azevedo, Cícero Armídio Gomes Dias, Lúcia Martins Teixeira,
In the present study, a total of 455 enterococcal isolates, recovered from patients living in the city of Porto Alegre, State of Rio Grande do Sul, Brazil, during the period from July 1996 to June 1997, were identified to the species level by conventional biochemical and microbiological tests, and assayed for their susceptibilities to antimicrobial agents. The genetic diversity of antimicrobial resistant strains was evaluated by pulsed-field gel electrophoresis (PFGE) analysis of SmaI restricted ...
Tópico(s): Antibiotic Resistance in Bacteria
2006 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo
Produção Nacional
Revisado por pares
Apoena Aguiar Ribeiro, Cícero Armídio Gomes Dias, M.C. Silva-Carvalho, Laura Berquó, Fabienne Antunes Ferreira, Raquel Neves Soares Santos, Bernadete Teixeira Ferreira‐Carvalho, Agnes Marie Sá Figueiredo,
ABSTRACT Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged in the southwestern Pacific, North America, and Europe. These S. aureus isolates frequently shared some genetic characteristics, including the SCC mec type IV and lukS-lukF genes. In this paper we show that typical CA-MRSA isolates have spread to South America (Brazil).
Tópico(s): Bacterial Identification and Susceptibility Testing
2005 - American Society for Microbiology | Journal of Clinical Microbiology
Produção Nacional
Revisado por pares
Pedro Alves d’Azevedo, Ana Lúcia Saraiva Gonçalves, Maiara Isabel Musskopf, Carina G. Ramos, Cícero Armídio Gomes Dias,
Extended spectrum beta-lactamase (ESBL) production by Klebsiella sp. and E. coli is an emerging problem. In this study, 107 clinical isolates (53 E. coli, 47 K. pneumoniae and 7 K. oxytoca) screened as ESBL producers by the NCCLS disk diffusion procedure were submitted to a double disk confirmatory test (DDT) and to the E-test double strip for confirmation of ESBL production by demonstration of clavulanic acid inhibition effect (CAIE). Only 72/107 (67%) of the isolates were confirmed as ESBL producers ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2004 - Elsevier BV | The Brazilian Journal of Infectious Diseases
Produção Nacional
Revisado por pares
Juliana Caierão, Maiara Isabel Musskopf, Silvana Vargas Superti, Eliane Würdig Roesch, Cícero Armídio Gomes Dias, Pedro Alves d’Azevedo,
Coagulase-negative staphylococci (CNS) are the major cause of nosocomial infections. Methicillin-resistant strains are particularly important because they narrow therapeutic options. Detecting methicillin resistance among CNS has been a challenge for years. The objective of this study was to determine the accuracy of an agar screening test (0.6 and 4 microg oxacillin ml(-1)), disc diffusion and the automated MicroScan system to characterize methicillin resistance among CNS. One hundred and seventy ...
Tópico(s): Bacterial biofilms and quorum sensing
2004 - Microbiology Society | Journal of Medical Microbiology
Produção Nacional
Revisado por pares
Cláudia Rezende Vieira de Mendonça-Souza, Maria da Glória S. Carvalho, Rosana Rocha Barros, Cícero Armídio Gomes Dias, Jorge Luiz Mello Sampaio, Angela C.D. Castro, Richard R. Facklam, Lúcia Martins Teixeira,
We investigated the occurrence and phenotypic and genotypic characteristics of erythromycin-resistant Streptococcus pneumoniae strains isolated in three major states in Brazil, from 1990 to 1999. Of the 931 pneumococcal strains evaluated, 40 (4.3%) were erythromycin-resistant (Ery-R). Among the 40 Ery-R strains, 90.0%, 80.0%, 27.5%, 5.0%, and 2.5% were resistant to tetracycline, trimethoprim-sulfamethoxazole, penicillin, chloramphenicol, and rifampin, respectively. None of the strains were resistant ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2004 - Mary Ann Liebert, Inc. | Microbial Drug Resistance