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Directory of Open Access Journals (DOAJ)

Primary Document Acesso aberto

A. R.T.D.A.L. M.,

Pressmark Cup. 405 b. 41 (4) Book.

1809 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Revisado por pares

Joris de Wit, Ruud F. Toonen, Matthijs Verhage,

... proteases from single secretory vesicles using pHluorin-tagged cargo in cortical neurons. Stimulation triggered transient and persistent ... events. Transient events represented full release followed by cargo diffusion or incomplete release followed by vesicle retrieval, ... neuroendocrine cells. Unexpectedly, we also observed that certain cargo, such as Semaphorin 3A (Sema3A), was delivered at ... deposits and transient events were observed for single cargo and both were SNARE (soluble N -ethylmaleimide-sensitive ...

Tópico(s): Neuroscience and Neuropharmacology Research

2009 - Society for Neuroscience | Journal of Neuroscience

Artigo Acesso aberto Revisado por pares

Inês S. Alencastre, Tony A. Rodrigues, Cláudia P. Grou, Marc Fransen, Clara Sá-Miranda, Jorge E. Azevedo,

... data gathered until now suggest that cytosolic PEX5·cargo protein complexes dock at the peroxisomal docking/translocation ... in vitro system and that call for a cargo protein-centered perspective instead. Here we describe a ... obtained with it suggest that translocation of a cargo protein across the peroxisomal membrane, including its release ... data gathered until now suggest that cytosolic PEX5·cargo protein complexes dock at the peroxisomal docking/translocation ... in vitro system and that call for a cargo protein-centered perspective instead. Here we describe a ...

Tópico(s): Signaling Pathways in Disease

2009 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

Giles Smith, Andrew Robson, Janice Turner, Else Churchill, Christina Hardyment, Cath Urquhart, Bob Persson, Richard Whitehead, Robert Cole, Portia Colwell, Rupert Mellor, Sarah Potter, Starry Eyed, Laurence Llewelyn-Bowen, Gary Duncan, Jane MacQuitty, Jon Clarke, Simon Hills, Andrew Marshall, Robert Thicknesse, John Hartley, Peter Hole, Paul Hoggart, R. F. Foster, Anita James, Tibor Fischer, Richard Hobson, Martin Richards, Pabulum, Ivo Tennant, Sam Coates, Tony Halpin and Gien Owen, Martin Thompson, Philip Howard, Hannah Betts, Ian Cobain, Phillip Hodson, Christine Seib, Suna Erdem, Rachel Campbell-Johnston, Glen Owen, Sam Coates and Tony Halpin, Melissa Katsoulis, Nic Hopkins, Michael Bracewell, N. H. Parmee, Alison Kervin, Kate Reardon, CC, Clive Davis, Elizabeth Judge, David Atkinson, Lucia Van Der Post, Carl Mortished, Patrick Kidd, GS, Simon Jenkins, Jane Taylor-Hayhurst, Patrick Barkham, Roger Maynard, James Hider, Kevin Eason, Jenny Knight, Ask Aggie, Nilgin Yusuf, Sam Lister, Clare Stewart, Charles Gargent, Giles Coren, Andrew Norfolk, David Sharrock, Pat Gibson, David McVay, Nancy Durrant, Tony Halpin, Sam Coates and Glen Owen, Anne Spackman Property Editor, Hilary Rose, Stewart Tendler Crime Correspondent, Katherine Swift, EP, Anthony Browne, Dominic Walsh, G. R. Thomas, Anthony Ralston, Victoria Segal, Bobby Robson, Nicola Smith, Dr Jane Collins, Magic Sponge, Jeanette Winterson, Angela Jameson Industrial Correspondent, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Dan Sabbagh, Heather Beresford, Jo Morris, Alan Hamilton, Stephen Farrell, Elizabeth Hudson, Oliver Wright Health Correspondent, Caitlin Moran, Sir Roy Strong, Alice Hart-Davies, Mark Bellis, Anna Blundy, Charles Bremner, Paddy Barry, Paul Mardles, Mark Pougatch, Stefanie Marsh, Damian Barr, Nicholas Wapshott, Derwent May, Arwa Haider, JJ, Tom Petherick, Russell Kempson, Paula Hawkins, Mary Gold, Ed Potton, Oliver Kay, Norman Giller, Luke Coppen, Stephen Anderton, Sarah Vine, Mark Atherton, Jonah Goldberg, John Westerby, Clinton Cards, Mark Henderson Science Correspondent, Sam Coates, Chris Power, Simon de Bruxelles, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Russell Kempson and David McVay, Amanda Platell, Stuart Miles, Anne Spackman Commentary, AF, David Powell Athletics Correspondent, Nick Barlay, Raymond Keene, Lucia Adams, Adam Sage, Matthew Pryor, Rod Liddle, Sean MacAulay, Cella Dodd, Peter Howarth, Robin Ash, Greg Hurst Parliamentary Correspondent, Xan Rice, Nigel Hawkes, Neville Scott, Charles Gant, Chris Campling, Shirley English and Peter Stevenson, Melissa Kite, Russell Hotten, Peter Hunter, Bob Harris, Xan Rice and Alex Hawkes, Roger Boyes, Catharine Morris, Angla Jameson Industrial Correspondent, Fred Dellar, Peter Dixon, Helen Nugent's, Caroline Charles Jones, Sarah Dunant, S. E. Harris, Tony Cascarino, David Hands Rugby Correspondent, Victoria O'brien, Chris Condron, Sophia Lyde, John Allison, Nigel Kendall, Nick Szczepanik, Joanna Pitman, Brian Case, Robert Crampton, Trevor McAvoy, Mike Brewer, Quentin Bell, David Hoppit, Matthew Parris, Jennai Cox, George Caulkin, Chris McGrath, J. R. Milner, Jonathan Rendall, Doug McKinlay, Ingrid Mansell, Alan Franks, Alan Lee, John Lister-Kaye, Iain Finlayson, Tim Wapshott, Sheila Keating, DC, Ben MacIntyre, Anthony J. Carr, Jeremy Hart, John Naish, Brian Glanville, Richard Beeston Diplomatic Editor, John Turnbull, Alison Gibson, Philip Webster and Michael Evans, Richard Miles, Sara Wheeler, Lea Paterson, Anne Ashworth Personal Finance Editor, Kieran Falconer, Gary Duncan Economics Correspondent, Mark Henderson, Martin Waller, Michael Horsnell, Chris Ayres, James Maxwell, Tom Bawden and Sarah Butler, Annabelle Thorpe, Mark Baldwin, Laura Peek, Sarah Butler, Victoria Smith, Benedict Nightingale, Darian Leader, Martin Knowles, Heath Brown, Jonathan Meades, Stephen Dalton, Jill Crawshaw, Leo Lewis, Alyson Rudd, David Powell, Elizabeth Judge and Tom Bawden, Tom Chesshyre, Robert Cole Personal Investor, Annabelle Thorpe and Caroline Hendrie, Valerie Grove, Geoffrey Harrison, Abigail Rayner, James Christopher, Michael Holroyd, Simon Crompton, Oliver Nielson, Allan Hall, Alan Lee Racing Correspondent, Owen Slot, Andrew Michael, Tony Kelly, Cath Urquhart Travel Editor, Michael Mates, Jan Raath, Patience Wheatcroft, Christopher Irvine, Irma Kurtz, Chloe Bryan-Brown, JHJ,

... Company In … Babules Kate Reardon Six Great.. . Slilmline Cargos The Travel Collection Cart … The Moment I Wake ...

2003 - Gale Group | TDA

Revisão Acesso aberto Revisado por pares

Max A. Schlager, Casper C. Hoogenraad,

Synaptic cargo trafficking is essential for synapse formation, function and plasticity. In order to transport synaptic cargo, such as synaptic vesicle precursors, mitochondria, neurotransmitter receptors ... cytoskeleton and are highly regulated so that different cargos can be transported to distinct synaptic specializations at both pre- and post-synaptic sites. How synaptic cargos achieve specificity, directionality and timing of transport is ... demonstrate that the docking of motors to their cargos is a key control point. Moreover, precise spatial ...

Tópico(s): Cellular transport and secretion

2009 - BioMed Central | Molecular Brain

Jornais Acesso aberto

St. Philips and St. Michaels, Pink, Tau, Leo, William D. Porter, President of the Senate, James Simons Speaker House of Representatives, Thos. D. Walker, President,

... Port of Key West, Their Value, with Their Cargos, Expenses,, Ship News Wind N.w., Ship News ...

1860 - Gale Group | SAS Part 1

Carta Acesso aberto Revisado por pares

Shaohua Xiao, Lily Yeh Jan,

... of the kinesin superfamily (KIFs) recognize specific transmembrane cargo proteins and direct them from the cell body ... of how a motor protein determines whether its cargo is destined for the axon or for dendrites. ... measured the transport efficacy (transport rate) of motor-cargo complexes. As the dendritic transport of NR2B and ... rates of these molecular motors with and without cargo proteins. The authors find that the motor domain ... it seems likely that some aspect of the cargo or of the motor-cargo complex dictates the ...

Tópico(s): Neurogenesis and neuroplasticity mechanisms

2009 - Cell Press | Cell

Jornais Acesso aberto

J. C. Winsmith, Captain Company H., Maj. Gen. E. Kirby Smith, Jefferson Davis, J. P. Benjamin, Secretary of State, C. F. Hall, F., X., Personne, Confederate,

... money realized by the sales of vessels and cargos at that port has been distributed, though some ...

1862 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Leonardus M. I. Koharudin, William Furey, Hao Liu, Yongjian Liu, Angela M. Gronenborn,

Subcellular retrograde transport of cargo receptors from endosomes to the trans-Golgi network is critically involved in a broad range of physiological and pathological processes ... retromer-mediated regulation of retrograde trafficking of transmembrane cargo receptors. Subcellular retrograde transport of cargo receptors from endosomes to the trans-Golgi network ... retromer-mediated regulation of retrograde trafficking of transmembrane cargo receptors. The early work on retromer revealed its role in the trafficking of cargo proteins between endosomes and the trans-Golgi network ( ...

Tópico(s): Erythrocyte Function and Pathophysiology

2009 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Stephen D.B. Goldman, Jeffrey P. Krise,

... notably the hyper-accumulation of cholesterol and other cargo in lysosomes. We comparatively evaluated the kinetics of [ ... another in the egress of membrane-impermeable lysosomal cargo. To investigate the basis for these differences, we ... be the initial step in the egress of cargo from lysosomes. We show here that cells with ... reformation of lysosomes and the release of lysosomal cargo-containing membrane vesicles. Collectively, these results suggest that ... in the egress of certain membrane-impermeable lysosomal cargo. The rare neurodegenerative disease Niemann-Pick Type C ( ...

Tópico(s): Cellular transport and secretion

2009 - Elsevier BV | Journal of Biological Chemistry

Livro Acesso aberto

Project Muse

Artigo Acesso aberto Revisado por pares

Catherine A. Bue, Charles Barlowe,

... free assays that monitor interactions with pro-ALP cargo and packaging into COPII vesicles. Mutations in the ... adaptor for a variety of Type II transmembrane cargo proteins and requires domain-specific interactions with both cargo and coat subunits to promote efficient secretory protein ... free assays that monitor interactions with pro-ALP cargo and packaging into COPII vesicles. Mutations in the ... adaptor for a variety of Type II transmembrane cargo proteins and requires domain-specific interactions with both ...

Tópico(s): Microtubule and mitosis dynamics

2009 - Elsevier BV | Journal of Biological Chemistry

Base Acesso aberto

... a longo prazo dos dados digitais estão a cargo do CINES (Centre Informatique National de l’Enseignement ...

Miscellaneous

Artigo Acesso aberto Revisado por pares

Kazuhito V. Tabata, Ken Sato, Toru Ide, Takayuki Nishizaka, Akihiko Nakano, Hiroyuki Noji,

Article17 September 2009free access Visualization of cargo concentration by COPII minimal machinery in a planar lipid membrane Kazuhito V Tabata Kazuhito V Tabata Department of Biomolecular Energetics, The Institute ... Here, we investigated the dynamics of fluorescently labelled cargo and non-cargo proteins during COPII vesicle formation using single-molecule ... molecule analysis showed that the Sar1p–Sec23/24p-cargo complex, but not the Sar1p–Sec23/24p complex, ... recruitment. On addition of a complete COPII mixture, cargo molecules start to assemble into fluorescent spots and ...

Tópico(s): Lipid metabolism and biosynthesis

2009 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Anbing Shi, Lin Sun, Riju Banerjee, Michael P. Tobin, Yinhua Zhang, Barth D. Grant,

... CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info After endocytosis, most cargo enters the pleiomorphic early endosomes in which sorting occurs. As endosomes mature, transmembrane cargo can be sequestered into inwardly budding vesicles for ... transport requires the retromer complex. Without retromer, recycling cargo such as the MIG-14/Wntless protein aberrantly ... associated clathrin also affects the recycling of retrograde cargo and has been shown to function in the ...

Tópico(s): Calcium signaling and nucleotide metabolism

2009 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Bracha Naim, David Zbaida, Shlomi Dagan, Ruti Kapon, Ziv Reich,

Article13 August 2009free access Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier Bracha Naim Bracha Naim Department of Biological Chemistry, ... non-specific, small, and pliant interaction network between cargo and FG repeats. Introduction Eukaryotic cell nuclei are ... nuclear export signal (NES) peptides displayed by the cargo (Paine et al, 1975; Corbett and Silver, 1997; ... of the number of conjugates present on the cargo (Figure 4A). Notably, at our resolution, the plot ...

Tópico(s): RNA regulation and disease

2009 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Lucas Malard Velloso, Kerstin Svensson, G. Schneider, Ralf F. Pettersson, Ylva Lindqvist,

... Golgi complex and appears to act as a cargo receptor for a subset of soluble glycoproteins exported ... Golgi complex and appears to act as a cargo receptor for a subset of soluble glycoproteins exported ... followed by the critical step of selection of cargo proteins to be exported from the ER to ... that export is an active regulated process, whereby cargo molecules are first localized to ER exit sites ... toward a better understanding of how glycans on cargo molecules interact with the lectin receptor, we have ...

Tópico(s): Cellular transport and secretion

2002 - Elsevier BV | Journal of Biological Chemistry

Artigo Revisado por pares

Anming Zhang, Yimin Zhang,

... market oligopoly model to examine the effect of cargo liberalization on competition between all-cargo carriers and mixed passenger/cargo carriers. We find that if home carriers engage in the joint production of cargo and passenger services, whereas foreign carriers produce the two outputs separately, then unilateral cargo liberalization by the home country will reduce home ... Our analysis suggests that the separation of air cargo and passenger rights might be fraught with difficulty ... Asia due to the characteristics of its air cargo market, in which most passenger carriers have substantial ...

Tópico(s): Transport and Economic Policies

2002 - Elsevier BV | Transportation Research Part E Logistics and Transportation Review

Artigo Acesso aberto Revisado por pares

John Kim, Wei‐Pang Huang, Per E. Strømhaug, Daniel J. Klionsky,

... the Apg/Cvt vesicle component Aut7, the Cvt cargo receptor Cvt19, and the Apg conjugation machinery, which ... the Apg/Cvt vesicle component Aut7, the Cvt cargo receptor Cvt19, and the Apg conjugation machinery, which ... autophagosome and Cvt vesicle, respectively) to sequester cytoplasmic cargo, followed by docking and fusion of the outer vesicle membrane with the vacuole to release the cargo-containing inner vesicle (the autophagic and Cvt bodies). ... been relatively well characterized and includes a requisite cargo concentration step in which cargo receptors bind their ...

Tópico(s): Endoplasmic Reticulum Stress and Disease

2002 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Katharina Ribbeck, Dirk Görlich,

... facilitated passage of nuclear transport receptors and their cargo complexes. We found that a simple hydrophobic interaction ... of NPCs. The rate of NPC passage of cargo–receptor complexes is, however, not dominated just by properties of the receptors. We found that large cargo domains drastically hinder NPC passage and require more ... species into a hydrophobic phase, whereby the receptor:cargo ratio determines the solubility in that permeability barrier. ... 1999). They circulate between nucleus and cytoplasm, recognize cargo molecules and transfer them from one side of ...

Tópico(s): RNA regulation and disease

2002 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Sheo K. Mishra,

... access Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor Sanjay K. Mishra Sanjay ... into the cell interior. A major mode of cargo selection at the bud site is via the ... a typical member of a growing family of cargo-specific adaptor proteins, including β-arrestin, AP180, epsin, ... coat assembly at the plasma membrane by synchronizing cargo selection and lattice polymerization events. Introduction Clathrin-coated ... adaptors can efficiently coordinate clathrin lattice assembly with cargo selection. It is clear that not all cargo ...

Tópico(s): Pancreatic function and diabetes

2002 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Emmanuel G. Reynaud, Jeremy C. Simpson,

... the secretory pathway requires the correct interpretation of cargo sorting signals in a precise and timely fashion ... of the membrane, followed by the selection of cargo. Following budding, these vesicles are directed towards the ... and then uncoat prior to membrane fusion and cargo delivery. Studies in the yeast Saccharomyces cerevisiae have ... to selectively recognize and sort this plethora of cargo accumulating in the ER. Using a large-scale ... and Erv29p, selectively bind certain transmembrane and soluble cargo, respectively, thereby providing a critical link between cargo ...

Tópico(s): Lipid Membrane Structure and Behavior

2002 - Springer Nature | EMBO Reports

Artigo Acesso aberto Revisado por pares

Daniel A. Gilchrist, Michael Rexach,

... α subunit Kap60p binds to the NLS of cargo molecules in the cytoplasm, forming stable complexes that ... show that Cse1p accelerates dissociation of Kap60p·NLS-cargo complexes and Kap60p·Nup2p complexes by increasing the ... activity and to the accumulation of Kap60p·NLS-cargo complexes in the nucleoplasm of yeast. We discuss ... directionality in the movement of Kap60p and NLS-cargos across the nuclear pore complex. The yeast karyopherin ... α subunit Kap60p binds to the NLS of cargo molecules in the cytoplasm, forming stable complexes that ...

Tópico(s): Genomics and Chromatin Dynamics

2003 - Elsevier BV | Journal of Biological Chemistry