Produção Nacional
Revisado por pares
Nadya B. Carneiro, Daniel R. Diniz‐Santos, Carlos Amorim, Cláudio Galeno, Juliana Raposo, Luiz Brandão, M. A. L. Magalhães, Rômulo Cathalá, Saulo Sardeiro, Caroline Mello, Luciana Rodrígues Silva,
... Nadya B. MD; Diniz-Santos, Daniel R. MD; Amorim, Carlos; Galeno, Cláudio; Raposo, Juliana; Brandão, Luiz; Magalhães, Matheus; ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2006 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Paulo Navarro‐Costa, Luı́sa Pereira, Cı́ntia Alves, Leonor Gusmão, Carmen Proença, Pedro Marques‐Vidal, Tiago Rocha, Sónia Cristina Heleno Correia, Sónia Jorge, António J. R. Neves, Ana Paula Soares, Joaquim Nunes, Carlos Calhaz–Jorge, António Amorim, Carlos E. Plancha, João Gonçalves,
The AZFc region of the human Y chromosome is a highly recombinogenic locus containing multi-copy male fertility genes located in repeated DNA blocks (amplicons). These AZFc gene families exhibit slight sequence variations between copies which are considered to have functional relevance. Yet, partial AZFc deletions yield phenotypes ranging from normospermia to azoospermia, thwarting definite conclusions on their real impact on fertility.The amplicon content of partial AZFc deletion products was characterized ...
Tópico(s): Sperm and Testicular Function
2007 - BioMed Central | BMC Genomics
Produção Nacional
Revisado por pares
Mariana Mara Buen, Eliana Amaral, Renato T. Souza, Renato Passini, Giuliane Jesus Lajos, Ricardo Porto Tedesco, Marcelo Luís Nomura, Tábata Z. Dias, Patrícia Moretti Rehder, Maria Helena de Sousa, José Guilherme Cecatti, Sérgio Tadeu Martins Marba, Jacinta P. Matias, Nelson Lourenço Maia Filho, Vera Therezinha Medeiros Borges, Laércio R. Oliveira, Tenílson Amaral Oliveira, Augusta M. B. Assumpção, Maria Elizabeth Lopes Moreira, Marcela A. F. Guedes, Cintia E. Senger, Janete Vettorazzi, Francisco Eulógio Martinez, Silvana Maria Quintana, Patrícia P. S. Melli, Antonio C. F. Barbosa Lima, Débora F. Leite, Elias F. Melo, Dênis José Nascimento, Edson Gomes Tristão, Luciana F. Siqueira, Pedro R. Coutinho, Ruth Guinsburg, Ana Cristina Perez Zamarian, Eduardo de Souza, Marília G. Martins, Marynea V. Nunes, Cláudio Sérgio Medeiros Paiva, Djacyr Magna Cabral Freire, Moisés Diôgo de Lima, Ana Maria Feitosa Porto, Isabela Cristina Coutinho de Albuquerque Neiva Coêlho, Adriana Suely Oliveira Melo, Fabiana O. Melo, Melânia Maria Ramos Amorim, Carlos A. S. Menezes, Marcelo de Amorim Aquino, Francisco Edson Lucena Feitosa, George N. Chaves, M.R.F. Silveira, Nelson Sass, Fátima Aparecida Henrique Lotufo, Kaliane P. Uzilin, Carla Betina Andreucci, Elvira A. O. Zanette,
Abstract Spontaneous preterm birth (sPTB) is a major pregnancy complication involving biological, social, behavioural and environmental mechanisms. Workload, shift and intensity may play a role in the occurrence of sPTB. This analysis is aimed addressing the effect of occupational activities on the risk for sPTB and the related outcomes. We conducted a secondary analysis of the EMIP study, a Brazilian multicentre cross-sectional study. For this analysis, we included 1,280 singleton sPTB and 1,136 ...
Tópico(s): Maternal and Perinatal Health Interventions
2020 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Maísa Ferreira Miranda, Clement Hamani, Antà ́nio-Carlos G. de Almeida, Beatriz Oliveira Amorim, Carlos Eduardo Macedo, Maria José da Silva Fernandes, José N. Nobrega, Mayra C. Aarão, Ana Paula Madureira, Antà ́nio M. Rodrigues, Mônica L. Andersen, Sérgio Tufik, Luiz E. Mello, Luciene Covolan,
Despite the effectiveness of anterior thalamic nucleus (AN) deep brain stimulation (DBS) for the treatment of epilepsy, mechanisms responsible for the antiepileptic effects of this therapy remain elusive. As adenosine modulates neuronal excitability and seizure activity in animal models, we hypothesized that this nucleoside could be one of the substrates involved in the effects of AN DBS. We applied five days of stimulation to rats rendered chronically epileptic by pilocarpine injections and recorded ...
Tópico(s): Adenosine and Purinergic Signaling
2014 - Frontiers Media | Frontiers in Cellular Neuroscience
Produção Nacional
Revisado por pares
Luiz Vicente Ribeiro Ferreira da Silva Filho, Paulo José Cauduro Maróstica, Rodrigo Abensur Athanazio, Francisco J.C. Reis, Neiva Damaceno, Ângela Tavares Paes, Adilson Yuuji Hira, David Schlesinger, Fernando Kok, Margarida D. Amaral, Mara Lícia Machado Antunes, Lilian Cristina Ferreira Andries, Virginia Auxiliadora Freitas de Castro, Fabíola Villac Adde, Maria Fernanda Botelho Hernandez Perez, Vera Dantas, Luciana de Freitas Velloso Monte, Adriana Goya, Samia Zahi Rached, Lusmaia Damaceno Camargo Costa, Lorenna Junqueira Almeida Prado, Elizabet Vilar Guimarães, Ana Cristina de Carvalho Fernández Fonseca, Marina Pires Nishi, Carlos Antônio Riedi, Nelson Augusto Rosário Filho, Mariane Gonçalves Martynychen Canan, Maria Inez Machado Fernandes, Albin Eugênio Augustin, Rosângela Villela Garcia, Maria Margarete da Silva Zembrzuski, Kátia Izabel de Oliveira, Anneliese Hoffmann, Cláudio Ricachinevsky, Paulo de Tarso Roth Dalcin, Bruna Ziegler, Daniela de Souza Paiva Borgli, Daniele Menezes Torres Ferrao, Elizabeth Passos Simoes da Silva, Marı́a Angélica Santana, Maria Amenaide Carvalho Alves de Sousa, Claudia de Castro e Silva, Evalto Monte de Araujo Filho, Tiago Neves Veras, N Ludwig Neto, Luiz Roberto Ágea Cutolo, A Vergara, Suzana Fonseca Oliveira Melo, Maria do Espírito Santo Almeida Moreira, Roberta de Cássia Nunes Cruz Melotti, Fernanda Barbosa dos Santos Malini, Marcelo Bicalho de Fuccio, Bruno Porto Pessoa, Concetta Esposito, Paulo Kussek, Glaunir Maria Foletto, Leonardo Araújo Pinto, Matias Epifânio, Marcelo Tadday Rodrigues, Marta Cristina Teixeira Duarte, Daniela Góis Meneses, Valéria de Carvalho Martins, Sônia Elenita Lopes Valente, Arlan de Azevedo Ferreira, Constantino Giovanni Braga Cartaxo, Denise Maria Costa Haidar, Mônica de Cássia Firmida, Marcos César Santos de Castro, Edna Lúcia Souza, Laís Ribeiro Mota, Katharina Vidal de Negreiros Moura, Joaquim Carlos Rodrigues, Clóvis R. Nakaie, Tânia Wrobel Folescu, Izabela Rocha Sad, Murilo Carlos Amorim de Britto, Carlos Henrique Medeiros Castelletti, Cláudia Mello Gonçalves, Lúcia Harumi Muramatu, Gilberto Bueno Fischer, Giesela Fleischer Ferrari, Luciana Oliveira Silvano Tostes, Carmen Sílvia Bertuzzo, Fernando Augusto Lima Marson, Sônia Mayumi Chiba, Marcela Duarte de Sillos,
Background The Brazilian population has a tri-hybrid composition with a high degree of ethnic admixture. We hypothesized that Brazilian individuals with CF from different Brazilian regions have a specific distribution of CFTR variants. Methods Individuals with CF with data available in the Patient Registry and without an established genotype were submitted to CFTR sequencing by Next Generation Sequencing (NGS) methodology, and results were anonymously incorporated to the Registry Database. Genotyping ...
Tópico(s): Genomics and Rare Diseases
2020 - Elsevier BV | Journal of Cystic Fibrosis
Produção Nacional
Revisado por pares
Luiz Vicente Ribeiro Ferreira da Silva Filho, Flavia de Aguiar Ferreira, Francisco J.C. Reis, Murilo Carlos Amorim de Britto, Carlos Emílio Levy, O Clark, José Dirceu Ribeiro,
Evidence-based techniques have been increasingly used in the creation of clinical guidelines and the development of recommendations for medical practice. The use of levels of evidence allows the reader to identify the quality of scientific information that supports the recommendations made by experts. The objective of this review was to address current concepts related to the clinical impact, diagnosis, and treatment of Pseudomonas aeruginosa infections in patients with cystic fibrosis. For the ...
Tópico(s): Cystic Fibrosis Research Advances
2013 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Maria Luı́s Amorim, Carlos Vasconcelos, Duarte C. Oliveira, Ana Azevedo, Elsa Calado, Nuno A. Faria, Marta Pereira, Ana Castro, Alice T. Campos Moreira, Ernestina Aires, José Manuel Cabeda, Maria Helena Ramos, José Manuel Amorim, Hermı́nia de Lencastre,
This two-year study investigated the epidemiology of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) among patients and healthcare workers (HCWs) in two wards with a high frequency of MRSA isolation, at Hospital Geral de Santo António (HGSA), Portugal. Three point-prevalence surveys per year were carried out. A case-control approach was used to identify potential risk factors associated with MRSA carriage among patients. Incidence rates and risk factors of MRSA carriage among ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2009 - Mary Ann Liebert, Inc. | Microbial Drug Resistance
Produção Nacional
Revisado por pares
Rodrigo Abreu, Pedro Figueiredo, Paulo Beckert, José Pedro Marques, Samuel Amorim, Carlos Alberto Caetano, Pedro Carvalho, Carla Sá, Ricardo Cotovio, Joana Cruz, Tiago Dias, Gonçalo Fernandes, Elton Gonçalves, César Leão, Alexandre Leitão, João Lopes, Eduardo Machado, Monica Araujo das Neves, André Luiz de Oliveira, Ana Isabel Pereira, Bruno Pereira Pereira, Fernando Ribeiro, Luis M Silva, Filipe Antônio de Barros Sousa, Tânia Tinoco, Vítor Hugo Teixeira, Mónica Sousa, João Brito,
Nutrition is an undeniable part of promoting health and performance among football (soccer) players. Nevertheless, nutritional strategies adopted in elite football can vary significantly depending on culture, habit and practical constraints and might not always be supported by scientific evidence. Therefore, a group of 28 Portuguese experts on sports nutrition, sports science and sports medicine sought to discuss current practices in the elite football landscape and review the existing evidence on ...
Tópico(s): Exercise and Physiological Responses
2021 - BMJ | BMJ Open Sport & Exercise Medicine
Ana Coelho, Henrique M. Fernandes, Ricardo Magalhães, Pedro Silva Moreira, Paulo Marques, José Miguel Soares, Liliana Amorim, Carlos Portugal‐Nunes, Teresa Costa Castanho, Nadine Correia Santos, Nuno Sousa,
Normal aging is characterized by structural and functional changes in the brain contributing to cognitive decline. Structural connectivity (SC) describes the anatomical backbone linking distinct functional subunits of the brain and disruption of this communication is thought to be one of the potential contributors for the age-related deterioration observed in cognition. Several studies already explored brain network's reorganization during aging, but most focused on average connectivity of the whole- ...
Tópico(s): Neural dynamics and brain function
2021 - Wiley | Journal of Neuroscience Research
Ana Coelho, Henrique M. Fernandes, Ricardo Magalhães, Pedro Silva Moreira, Paulo Marques, José Miguel Soares, Liliana Amorim, Carlos Portugal‐Nunes, Teresa Costa Castanho, Nadine Correia Santos, Nuno Sousa,
Abstract Previous studies have shown an association between cognitive decline and white matter integrity in aging. This led to the formulation of a “disconnection hypothesis” in the aging-brain, which states that the disruption in cortical network communication may explain the cognitive decline during aging. Although some longitudinal studies have already investigated the changes occurring in white matter microstructure, most focused on specific white matter tracts. Our study aims to characterize ...
Tópico(s): Multiple Sclerosis Research Studies
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Patrícia de Faria Lainetti, Andressa Brandi, Antonio Fernando Leis‐Filho, Maria Carolina Mangini Prado, Priscila Emiko Kobayashi, Renée Laufer Amorim, Carlos Eduardo Fonseca‐Alves,
Mammary tumors affect intact and elderly female dogs, and almost 50% of these cases are malignant. Cell culture offers a promising preclinical model to study this disease and creates the opportunity to deposit cell lines at a cell bank to allow greater assay reproducibility and more reliable validation of the results. Another important aspect is the possibility to establish models and improve our understanding of tumor characteristics, such as vasculogenic mimicry. Because of the importance of cancer ...
Tópico(s): Angiogenesis and VEGF in Cancer
2020 - Frontiers Media | Frontiers in Veterinary Science
Produção Nacional
Revisado por pares
Graciéle Cunha Alves de Menezes, Bárbara Alves Porto, Soraya Sander Amorim, Carlos Leomar Zani, Tânia Maria de Almeida Alves, Policarpo Ademar Sales, Silvane Maria Fonseca Murta, Jefferson Cárdia Simões, Betânia Barros Cota, Carlos A. Rosa, Luiz Henrique Rosa,
Tópico(s): Insect and Arachnid Ecology and Behavior
2020 - Springer Science+Business Media | Extremophiles
Produção Nacional
Revisado por pares
Jucier Gonçalves Júnior, Marcial Moreno Moreira, Woneska Rodrigues Pinheiro, Liromaria Maria de Amorim, Carlos Kennedy Tavares Lima, Cláudio Gleidiston Lima da Silva, Modesto Leite Rolim Neto,
: In Latin America there are about 45 million indigenous people in 826 communities that represent 8.3% of the population. An estimated 798,365 Aboriginal and Torres Strait Islander were in Australia, 5,2 million indigenous people living in America and 2,13 million in Canada. Racial/ethnic disparities in mental health service use have increased especially in the context of the new coronavirus pandemic. Thus, we aimed to describe the mental health situation of the indigenous population in the context ...
Tópico(s): Migration, Education, Indigenous Social Dynamics
2020 - Elsevier BV | Psychiatry Research
Produção Nacional
Revisado por pares
Rubens Junqueira, Marcelo Ribeiro Viola, Jhones da Silva Amorim, Carlos Rogério de Mello,
The Brazilian savanna is one of the world’s 25 biodiversity hotspots. However, droughts can decrease water availability in this biome. This study aimed to analyze meteorological and hydrological droughts and their influence on the hydrological behavior in a Brazilian savanna basin. For that, hydrological indicators were calculated to analyze the hydrological behavior in the Pandeiros river basin (PRB). The Standardized Precipitation Index (SPI) and Standardized Streamflow Index (SSI) were calculated ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2020 - Multidisciplinary Digital Publishing Institute | Resources
Produção Nacional
Revisado por pares
Camila Dorotea Costa, André Augusto Justo, Priscila Emiko Kobayashi, Michelle M. Story, Chiara Palmieri, Renée Laufer Amorim, Carlos Eduardo Fonseca‐Alves,
The cancer cell population is heterogeneous, and cancer stem cells (CSCs) are important for tumor growth and maintenance. The CSC population is associated with different neoplastic characteristics, such as cell migration, resistance to apoptosis, radiation therapy and chemotherapy. To increase the knowledge of CSCs in canine prostate cancer (PC), we characterized CSC markers in canine PC tissues and tumorspheres. We performed immunohistochemistry of OCT3/4, Nestin, NANOG, CD44 and CD24 in 10 normal ...
Tópico(s): Fibroblast Growth Factor Research
2019 - Elsevier BV | The International Journal of Biochemistry & Cell Biology
Produção Nacional
Revisado por pares
Diogo Peixoto, João Amorim, Carlos Pinheiro, Luís Oliva-Teles, Inmaculada Varó, Renato de Medeiros Rocha, Natividade Vieira,
Artemia cysts have a huge economic importance for the aquaculture sector due to the fact that they are used as live feed for larviculture. Microplastics (MPs) are common and emergent pollutants in the aquatic environments, with unknown and potential long-term effects on planktonic species such as Artemia spp. When used as live feed, Artemia could transfer contaminants to fish along the food chain, with possible adverse effects on human health through their consumption. This study aims to assess the ...
Tópico(s): Nanoparticles: synthesis and applications
2019 - Elsevier BV | Ecotoxicology and Environmental Safety
Produção Nacional
Revisado por pares
Maria Carolina Mangini Prado, Sofia de Almeida Losant Macedo, Giulia Gumiero Guiraldelli, Patrícia de Faria Lainetti, Antonio Fernando Leis‐Filho, Priscila Emiko Kobayashi, Renée Laufer Amorim, Carlos Eduardo Fonseca‐Alves,
Canine mammary gland tumor (CMT) is one of the most important tumors in intact female dogs, and due its similarity to human breast cancer (BC), it is considered a model in comparative oncology. A subset of mammary gland tumors can show aggressive behavior, and a recurrent histological finding is the presence of vasculogenic mimicry (VM). VM is a process in which highly aggressive cancer cells fuse, forming fluid-conducting channels without endothelial cells. Although, VM has been described in canine ...
Tópico(s): Cancer Cells and Metastasis
2019 - Frontiers Media | Frontiers in Oncology
Produção Nacional
Revisado por pares
Renée Laufer Amorim, Carlos Eduardo Fonseca‐Alves, Rolando André Rios Villacis, Sandra Linde, Márcio de Carvalho, Simon J. Larsen, Fábio Albuquerque Marchi, Sílvia Regina Rogatto,
Canine carcinomas have been considered natural models for human diseases; however, the genomic profile of canine prostate cancers (PCs) has not been explored. In this study, 14 PC androgen-receptor-negative cases, 4 proliferative inflammatory atrophies (PIA), and 5 normal prostate tissues were investigated by array-based comparative genomic hybridization (aCGH). Copy number alterations (CNAs) were assessed using the Canine Genome CGH Microarray 4 × 44K (Agilent Technologies). Genes covered by recurrent ...
Tópico(s): Genomic variations and chromosomal abnormalities
2019 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
Suany Campos, Keila Rêgo Mendes, Lindenberg L. da Silva, Pedro Rodrigues Mutti, Salomão S. Medeiros, Laerte B. Amorim, Carlos Antônio Costa dos Santos, Aldrin Martin Pérez-Marin, Tarsila M. Ramos, Thiago V. Marques, Paulo Sérgio Lúcio, Gabriel Brito Costa, Cláudio Moisés Santos e Silva, Bergson Guedes Bezerra,
The energy balance closure obtained through the eddy covariance method is a problem which persists, despite advances in the development and improvement of instruments and recent efforts in the description of corrections and in the characterization of measuring uncertainties. In most places the sum of sensible and latent heat fluxes (H and λE) is less than available energy, i.e. the difference between net radiation (Rn) and soil heat flux (G). This study analyzed the annual and seasonal behavior of ...
Tópico(s): Soil and Unsaturated Flow
2019 - Elsevier BV | Agricultural and Forest Meteorology
Produção Nacional
Revisado por pares
Lorenna Alves Mattos-Moreira, Cláudia Fortes Ferreira, Édson Perito Amorim, Carlos Priminho Pirovani, Edson Mário de Andrade, M. A. Coelho Filho, Carlos Alberto da Silva Lédo,
Tópico(s): Plant-Microbe Interactions and Immunity
2018 - Springer Science+Business Media | Acta Physiologiae Plantarum
Produção Nacional
Revisado por pares
Thays Abreu, Aline Jardim Amorim, Carlos Roberto dos Santos, Anna Diva P. Lotufo, Carlos R. Minussi,
This work proposes a predictor system (multinodal forecasting) considering several points of an electrical network, such as substations, transformers, and feeders, based on an adaptive resonance theory (ART) neural network family. It is a problem similar to global forecasting, with the main difference being the strategy to align the input and output of the data with several parallel neural modules. Considering that multinodal prediction is more complex compared to global prediction, the multinodal ...
Tópico(s): Image and Signal Denoising Methods
2018 - Elsevier BV | Applied Soft Computing
Ana C. Cassoni, Ricardo Freixo, Ana I.E. Pintado, Manuela Amorim, Carlos Pereira, Ana Raquel Madureira, Manuela Pintado,
Pig slaughtering for meat production is a major worldwide industry that generates many byproducts that can cause environmental problems. Nonetheless, it is possible to have a management of these residues toward the reuse and valorization of these byproducts. One opportunity focuses on the extraction of value-added compounds such as keratin since pig hair is composed by 80% of this protein. There are some methods for keratin extraction from human hair as other sources such as wool and feathers, but ...
Tópico(s): Collagen: Extraction and Characterization
2018 - American Chemical Society | ACS Sustainable Chemistry & Engineering
Pedro Silva Moreira, Nadine Correia Santos, Teresa Costa Castanho, Liliana Amorim, Carlos Portugal‐Nunes, Nuno Sousa, Patrício Costa,
In this work, we examined the longitudinal measurement invariance of a battery composed of distinct cognitive parameters. A sample of 86 individuals (53.5% females; mean age = 65.73), representative of the Portuguese older population, with respect to sex, age and level of education was assessed twice over an average of two years. By means of a confirmatory factor analysis approach, we tested whether a two-factor solution [corresponding to measures of memory performance (MEM) and executive functioning ( ...
Tópico(s): Neural and Behavioral Psychology Studies
2018 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Ademir Calvo Fernandes, Pedro Luiz Pucci Figueiredo de Carvalho, Luiz Edivaldo Pezzato, João Fernando Albers Koch, Caroline Pelegrina Teixeira, Felipe Tenório Cintra, Flávia Motta Damasceno, Renée Laufer Amorim, Carlos Roberto Padovani, Margarida Maria Barros,
This study evaluated growth performance, hematological parameters, histological liver analysis, and production costs of Nile tilapia fed increasing levels of digestible protein, digestible energy, and choline. Twelve thousand Nile tilapia (148 ± 6.7 g) were randomly distributed into 80 1 m3 net cages, in a 5 × 2 × 2 factorial design with five digestible protein (DP) levels (24, 26, 28, 30, and 32% DP), two digestible energy (DE) levels (13.4 and 14.65 MJ DE kg− 1 diet), and two choline levels (0.0 and 1000 ...
Tópico(s): Reproductive biology and impacts on aquatic species
2016 - Elsevier BV | Aquaculture
Produção Nacional
Revisado por pares
Daniela Accorsi–Mendonça, Melina P. da Silva, George M. P. R. Souza, Ludmila Lima‐Silveira, Marlusa Karlen‐Amarante, Mateus R. Amorim, Carlos Eduardo L. Almado, Davi J. A. Moraes, Benedito H. Machado,
Despite several studies describing the electrophysiological properties of RVLM presympathetic neurons, there is no consensus in the literature about their pacemaking property, mainly due to different experimental approaches used for recordings of neuronal intrinsic properties. In this review we are presenting a historical retrospective about the pioneering studies and their controversies on the intrinsic electrophysiological property of auto-depolarization of these cells in conjunction with recent ...
Tópico(s): Heart Rate Variability and Autonomic Control
2016 - Frontiers Media | Frontiers in Physiology
Filipe V. Duarte, João A. Amorim, Carlos M. Palmeira, Anabela P. Rolo,
Mitochondria are key players in the maintenance of cellular homeostasis, as they generate ATP via OXPHOS. As such, disruption in mitochondrial homeostasis is closely associated with disease states, caused by subtle alterations in the function of tissues or by major defects, particularly evident in tissues with high metabolic demands. Adaptations in mitochondrial copy number or mitochondrial mass, and the induction of genes implicated in OXPHOS or in intermediary metabolism as well, depend on the ...
Tópico(s): Metabolism and Genetic Disorders
2015 - Bentham Science Publishers | Current Medicinal Chemistry
Manuel Vieira, Paulo J. Fonseca, M. Clara P. Amorim, Carlos Teixeira,
The study of acoustic communication in animals often requires not only the recognition of species specific acoustic signals but also the identification of individual subjects, all in a complex acoustic background. Moreover, when very long recordings are to be analyzed, automatic recognition and identification processes are invaluable tools to extract the relevant biological information. A pattern recognition methodology based on hidden Markov models is presented inspired by successful results obtained ...
Tópico(s): Underwater Acoustics Research
2015 - Acoustical Society of America | The Journal of the Acoustical Society of America
Mónica J.B. Amorim, Carlos P. Roca, Janeck J. Scott‐Fordsmand,
Engineered Nanoparticles (ENPs) present novel/added challenges to the established effect assessment modus operandi, requiring an update of used methods. ENPs are dimensionally and physically different from conventional chemicals, which imply that the metrics with which we relate effect and the type of effect responses are different from that of the conventional approach. Effects on organisms are often preceded by changes on the sub-organismal level (cell, genes), dedicated tools have vast potential ...
Tópico(s): Computational Drug Discovery Methods
2015 - Elsevier BV | Environmental Pollution
Produção Nacional
Revisado por pares
Philip J. Cooper, Martha Chico, Leila Denise Alves Ferreira Amorim, Carlos Sandoval, Maritza Vaca, Agostino Strina, Ana Clara Paixão Campos, Laura C. Rodrigues, Maurício L. Barreto, David P. Strachan,
Maternal geohelminth infections during pregnancy may protect against allergy development in childhood.We sought to investigate the effect of maternal geohelminths on the development of eczema, wheeze, and atopy during the first 3 years of life.A cohort of 2404 neonates was followed to 3 years of age in a rural district in coastal Ecuador. Data on wheeze and eczema were collected by means of questionnaire and physical examination at 13, 24, and 36 months of age. Atopy was measured based on skin prick ...
Tópico(s): Dermatology and Skin Diseases
2015 - Elsevier BV | Journal of Allergy and Clinical Immunology
Produção Nacional
Revisado por pares
Marcel Gianni C. da Silva, Raimundo Neilson Lima Amorim, Carlos C. da Camara, J.D. Fontenele-Neto, Benito Soto‐Blanco,
The present study aimed to evaluate the toxicity of aqueous extract of Chenopodium ambrosioides leaves. To measure acute toxicity, rats were administered 0, 0.3, 1.0, or 3.0 g/kg of aqueous extract from C. ambrosioides leaves by gavage. To analyze sub-chronic toxicity, rats were treated by oral gavage for 15 consecutive days with 0, 0.3, or 1.0 g/kg of extract of C. ambrosioides leaves. No animals from either trial exhibited any signs of toxicity. In the acute study, the highest dose of the extract ...
Tópico(s): Seed and Plant Biochemistry
2014 - Mary Ann Liebert, Inc. | Journal of Medicinal Food