Marta Castroviejo‐Bermejo, Cristina Cruz, Alba Llop‐Guevara, Sara Gutiérrez‐Enríquez, Mandy Ducy, Yasir H. Ibrahim, Albert Gris‐Oliver, Benedetta Pellegrino, Alejandra Bruna, Marta Guzmán, Olga Rodríguez, Judit Grueso, Sandra Bonache, Alejandro Moles‐Fernández, Guillermo Villacampa, Cristina Viaplana, Patricia Gómez, María Vidal, Vicente Peg, Xavier Serres, Graham Dellaire, Jacques Simard, Paolo Nucíforo, Isabel T. Rubio, Rodrigo Dienstmann, J. Carl Barrett, Carlos Caldas, José Baselga, Cristina Saura, Javier Cortés, Olivier Déas, Jos Jonkers, Jean‐Yves Masson, Stefano Cairo, Jean‐Gabriel Judde, Mark J. O’Connor, Orland Dı́ez, Judith Balmañà, Violeta Serra,
... Search for more papers by this author Carlos Caldas Carlos Caldas Cancer Research UK Cambridge Institute and Department ... Search for more papers by this author Carlos Caldas Carlos Caldas Cancer Research UK Cambridge Institute and Department of ...
Tópico(s): CRISPR and Genetic Engineering
2018 - Springer Nature | EMBO Molecular Medicine
Dana W.Y. Tsui, Muhammed Murtaza, Alvin Wong, Oscar M. Rueda, Christopher G. Smith, Dineika Chandrananda, Ross A. Soo, Hong Liang Lim, Boon Cher Goh, Carlos Caldas, Tim Forshew, Davina Gale, Wei Liu, James Morris, Francesco Marass, Tim Eisen, Tan Min Chin, Nitzan Rosenfeld,
... Search for more papers by this author Carlos Caldas Carlos Caldas Cancer Research UK Cambridge Institute, Li Ka ... Search for more papers by this author Carlos Caldas Carlos Caldas Cancer Research UK Cambridge Institute, Li Ka Shing ...
Tópico(s): Lung Cancer Research Studies
2018 - Springer Nature | EMBO Molecular Medicine
Eliana MC Tacconi, Sophie Badie, Giuliana De Gregoriis, Timo Reisländer, Xianning Lai, Manuela Porru, Cecilia Folio, John C. Moore, Arnaud Kopp, Júlia Baguña Torres, Deborah Sneddon, Marcus Green, Simon Dedic, Jonathan W. Lee, Ankita Sati Batra, Oscar M. Rueda, Alejandra Bruna, Carlo Leonetti, Carlos Caldas, Bart Cornelissen, Laurent Brino, Anderson J. Ryan, Annamaria Biroccio, Madalena Tarsounas,
... Search for more papers by this author Carlos Caldas Carlos Caldas Department of Oncology, Cancer Research UK Cambridge ... Search for more papers by this author Carlos Caldas Carlos Caldas Department of Oncology, Cancer Research UK Cambridge Institute, ...
Tópico(s): Cancer Genomics and Diagnostics
2019 - Springer Nature | EMBO Molecular Medicine
... AustraliaSearch for more papers by this authorCarlos H. Caldas, Corresponding Author Carlos H. Caldas Department of Civil, Architectural, and Environmental ... AustraliaSearch for more papers by this authorCarlos H. Caldas, Corresponding Author Carlos H. Caldas Department of Civil, Architectural, and Environmental Engineering, University ...
Tópico(s): Video Surveillance and Tracking Methods
2010 - Wiley | Computer-Aided Civil and Infrastructure Engineering
... UK Search for more papers by this author Carlos Caldas Corresponding Author [email protected] orcid.org/0000-0003- ... UK Search for more papers by this author Carlos Caldas Corresponding Author [email protected] orcid.org/0000-0003- ... author Author Information Long V Nguyen1,2 and Carlos Caldas *,1,2 1Department of Oncology and Cancer Research ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2021 - Springer Nature | EMBO Molecular Medicine
Jongchul Song, Carlos Caldas, Esin Ergen, Carl T. Haas, Burcu Akinci,
... for Tracking Pre-Fabricated Pipe Spools Jongchul Song, Carlos Caldas, Esin Ergen, Carl Haas, Burcu Akinci Abstract: The ...
Tópico(s): Outsourcing and Supply Chain Management
2004 - | Proceedings of the ... ISARC
Renaud Sabatier, Pascal Finetti, Émilie Mamessier, José Adélaı̈de, Max Chaffanet, H. Raza Ali, Patrice Viens, Carlos Caldas, Daniel Birnbaum, François Bertucci,
... Ali 4,5 , Patrice Viens 1,2,3 , Carlos Caldas 5 , Daniel Birnbaum 1 and François Bertucci 1, ...
Tópico(s): Cancer Genomics and Diagnostics
2014 - Impact Journals LLC | Oncotarget
Meng-Lay Lin, Hetal Patel, Judit Reményi, Christopher R. S. Banerji, Chun‐Fui Lai, Manikandan Periyasamy, Ylenia Lombardo, Claudia Busonero, Silvia Ottaviani, Alun Passey, Philip Quinlan, Colin A. Purdie, Lee B. Jordan, Alastair M. Thompson, Richard S. Finn, Oscar M. Rueda, Carlos Caldas, Jesús Gil, R. Charles Coombes, Frances V. Fuller-Pace, Andrew E. Teschendorff, Laki Buluwela, Simak Ali,
... Richard S. Finn 7 , Oscar M. Rueda 8 , Carlos Caldas 8 , Jesus Gil 9 , R. Charles Coombes 1 , ...
Tópico(s): Nuclear Receptors and Signaling
2015 - Impact Journals LLC | Oncotarget
Theresa E. Hickey, Connie M. Irvine, Heidi Dvinge, Gerard A. Tarulli, Adrienne R. Hanson, Natalie K. Ryan, Marie Pickering, Stephen N. Birrell, Dong Hu, Peter I. Mackenzie, Roslin Russell, Carlos Caldas, Ganesh V. Raj, Scott M. Dehm, Stephen R. Plymate, Robert K. Bradley, Wayne D. Tilley, Luke A. Selth,
... 4 , Peter I. Mackenzie 4 , Roslin Russell 5 , Carlos Caldas 5 , Ganesh V. Raj 6 , Scott M. Dehm ...
Tópico(s): Cancer-related Molecular Pathways
2015 - Impact Journals LLC | Oncotarget
Ruth Dannenfelser, Marianne Nome, Andliena Tahiri, Josie Ursini‐Siegel, Hans Kristian Moen Vollan, Vilde Drageset Haakensen, Åslaug Helland, Bjørn Naume, Carlos Caldas, Anne‐Lise Børresen‐Dale, Vessela N. Kristensen, Olga G. Troyanskaya,
... Haakensen 7 , Åslaug Helland 8 , Bjørn Naume 8 , Carlos Caldas 6 , Anne-Lise Børresen-Dale 4, 7 , Vessela ...
Tópico(s): Cancer Cells and Metastasis
2017 - Impact Journals LLC | Oncotarget
Jing Dong, Carlo Maj, Spiridon Tsavachidis, Quinn T. Ostrom, Puya Gharahkhani, Lesley Anderson, Anna H. Wu, Weimin Ye, Leslie Bernstein, Oleg Borisov, Julia Schröder, Wong‐Ho Chow, Marilie D. Gammon, Geoffrey Liu, Carlos Caldas, Paul D.P. Pharoah, Harvey A. Risch, Andrea May, Christian Gerges, Mario Anders, Marino Venerito, Thomas Schmidt, Jakob R. Izbicki, Arnulf H. Hölscher, Brigitte Schumacher, Yogesh K. Vashist, Horst Neuhaus, Thomas Rösch, Michael Knapp, Peter Krawitz, Anne C. Böhmer, Prasad G. Iyer, Brian J. Reid, Jesper Lagergren, Nicholas J. Shaheen, Douglas A. Corley, Ines Gockel, Rebecca C. Fitzgerald, Michael B. Cook, David C. Whiteman, Thomas L. Vaughan, Johannes Schumacher, Aaron P. Thrift, Jing Dong, Carlo Maj, Spiridon Tsavachidis, Quinn T. Ostrom, Puya Gharahkhani, Lesley Anderson, Anna H. Wu, Weimin Ye, Leslie Bernstein, Oleg Borisov, Julia Schröder, Wong‐Ho Chow, Marilie D. Gammon, Geoffrey Liu, Carlos Caldas, Paul D.P. Pharoah, Harvey A. Risch, Andrea May, Christian Gerges, Mario Anders, Marino Venerito, Thomas Schmidt, Jakob R. Izbicki, Arnulf H. Hölscher, Brigitte Schumacher, Yogesh K. Vashist, Horst Neuhaus, Thomas Rösch, Michael Knapp, Peter Krawitz, Anne C. Böhmer, Prasad G. Iyer, Brian J. Reid, Jesper Lagergren, Nicholas J. Shaheen, Douglas A. Corley, Ines Gockel, Rebecca C. Fitzgerald, Michael B. Cook, David C. Whiteman, Thomas L. Vaughan, Johannes Schumacher, Aaron P. Thrift,
Background & AimsEsophageal adenocarcinoma (EA) and its premalignant lesion, Barrett's esophagus (BE), are characterized by a strong and yet unexplained male predominance (with a male-to-female ratio in EA incidence of up to 6:1). Genome-wide association studies (GWAS) have identified more than 20 susceptibility loci for these conditions. However, potential sex differences in genetic associations with BE/EA remain largely unexplored.MethodsGiven strong genetic overlap, BE and EA cases were combined into ...
Tópico(s): Cancer-related gene regulation
2020 - Elsevier BV | Gastroenterology
H. Raza Ali, Hartland W. Jackson, Vito Riccardo Tomaso Zanotelli, Esther Danenberg, Jana Fischer, Helen Bardwell, Elena Provenzano, H. Raza Ali, M. Al Sa’d, Shahar Alon, Samuel Aparício, Giorgia Battistoni, Shankar Balasubramanian, Robert Becker, Bernd Bodenmiller, E. S. Boyden, Dario Bressan, Alejandra Bruna, B. Marcel, Carlos Caldas, Maurizio Callari, Ian G. Cannell, Helen Casbolt, N. Chornay, Yi Cui, A. Dariush, K. Dinh, A. Emenari, Y. Eyal-Lubling, Jean Fan, Edward A. Fisher, E. A. González-Solares, C. Gónzalez-Fernández, Daniel Goodwin, Wendy Greenwood, Francesco Grimaldi, Gregory J. Hannon, Owen Harris, Shelley Harris, Cristina Jauset, Johanna A. Joyce, Emmanouil D. Karagiannis, Tatjana Kovačević, Laura Kuett, Russell Kunes, A. Yoldaş, Dongbing Lai, Emma Laks, Hsuan Lee, M. Lee, Giulia Lerda, Y. Li, Andrew McPherson, Neal L. Millar, Claire M. Mulvey, Fiona Nugent, Ciara H. O’Flanagan, Marta Pàez‐Ribes, I. Pearsall, Fatime Qosaj, Andrew Roth, Oscar M. Rueda, Tamara Ruiz, Kirsty Sawicka, Leonardo A. Sepúlveda, Sohrab P. Shah, Abigail Shea, Anubhav Sinha, Adrian L. Smith, Simon Tavaré, Sandra Tietscher, Ignacio Vázquez-Garćıa, Siegfried Vogl, N. A. Walton, Asmamaw T. Wassie, Spencer S. Watson, Sonja Wild, Elena Williams, Jonas Windhager, C. Xia, Ping Zheng, Xiaowei Zhuang, Oscar M. Rueda, Suet‐Feung Chin, Samuel Aparício, Carlos Caldas, Bernd Bodenmiller,
Genomic alterations shape cell phenotypes and the structure of tumor ecosystems in poorly defined ways. To investigate these relationships, we used imaging mass cytometry to quantify the expression of 37 proteins with subcellular spatial resolution in 483 tumors from the METABRIC cohort. Single-cell analysis revealed cell phenotypes spanning epithelial, stromal and immune types. Distinct combinations of cell phenotypes and cell–cell interactions were associated with genomic subtypes of breast cancer. ...
Tópico(s): Cell Image Analysis Techniques
2020 - Nature Portfolio | Nature Cancer
Dimitra Georgopoulou, Maurizio Callari, Oscar M. Rueda, Abigail Shea, Alistair Martin, Agnese Giovannetti, Fatime Qosaj, A. Dariush, Suet‐Feung Chin, Larissa S. Carnevalli, Elena Provenzano, Wendy Greenwood, Giulia Lerda, Elham Esmaeilishirazifard, Martin O’Reilly, Violeta Serra, Dario Bressan, H. Raza Ali, M. Al Sa’d, Shahar Alon, Samuel Aparício, Giorgia Battistoni, Shankar Balasubramanian, Robert O. Becker, Bernd Bodenmiller, E. S. Boyden, Dario Bressan, Alejandra Bruna, Marcel Burger, Carlos Caldas, Maurizio Callari, Ian G. Cannell, Helen Casbolt, N. Chornay, Yi Cui, A. Dariush, K. Dinh, A. Emenari, Y. Eyal-Lubling, Jean Fan, Ali Fatemi, Edward A. Fisher, E. A. González-Solares, C. Gónzalez-Fernández, Douglas C. Goodwin, Wendy Greenwood, Francesco Grimaldi, Gregory J. Hannon, Owen Harris, Shelley Harris, Cristina Jauset, Johanna A. Joyce, Emmanouil D. Karagiannis, Tatjana Kovačević, Laura Kuett, Russell Kunes, Yoldaş A. Küpcü, Daniel Lai, Emma Laks, Hsuan Lee, M. Lee, Giulia Lerda, Y. Li, Andrew McPherson, Neal L. Millar, Claire M. Mulvey, Fiona Nugent, Ciara H. O’Flanagan, Marta Pàez‐Ribes, I. Pearsall, Fatime Qosaj, Andrew Roth, Oscar M. Rueda, Tamara Ruiz, Kirsty Sawicka, Leonardo A. Sepúlveda, Sohrab P. Shah, Abigail Shea, Anubhav Sinha, Adrian L. Smith, S. Tavaré, Sandra Tietscher, Ignacio Vázquez-Garćıa, Siegfried Vogl, N. A. Walton, Asmamaw T. Wassie, Spencer S. Watson, Joanna Weselak, Sonja Wild, Elena Williams, Jonas Windhager, Tristan Whitmarsh, C. Xia, Ping Zheng, Xiaowei Zhuang, Gordon B. Mills, H. Raza Ali, Sabina S. Cosulich, Gregory J. Hannon, Alejandra Bruna, Carlos Caldas,
The heterogeneity of breast cancer plays a major role in drug response and resistance and has been extensively characterized at the genomic level. Here, a single-cell breast cancer mass cytometry (BCMC) panel is optimized to identify cell phenotypes and their oncogenic signalling states in a biobank of patient-derived tumour xenograft (PDTX) models representing the diversity of human breast cancer. The BCMC panel identifies 13 cellular phenotypes (11 human and 2 murine), associated with both breast ...
Tópico(s): Breast Cancer Treatment Studies
2021 - Nature Portfolio | Nature Communications
Produção Nacional
Carlos Roberto Ceron, Ruy de Araújo Caldas, Carlos Roberto Félix, MARIA HERMELINDA MUNDIM, Isaac Roitman,
Purine nucleotide biosynthesis was studied in culture forms of Trypanosoma cruzi strain Y, Crithidia deanei (a reduviid trypanosomatid with an endosymbiote) and an aposymbiotic strain of C. deanei (obtained by curing C. deanei with chloramphenicol). Trypanosoma cruzi was found to synthesize purine nucleotides only fring incorporated into both adenine and guanine nucleotides. Similar results were obtained with guanine, indicating that this flagellate has a system for the interconversion of purine nucleotides. ...
Tópico(s): Biochemical and Molecular Research
1979 - Wiley | The Journal of Protozoology
Margarida Castro‐Caldas, Carlos B. Duarte, A.P. Carvalho, María Celeste Lopes,
The mechanisms by which glucocorticoids (GC) regulate annexin I (ANXA1) secretion in different cells are still a matter of debate. The aims of this study were to evaluate the ability of dexamethasone (Dex) to induce ANXA1 secretion and to investigate the roles of the intracellular free Ca2+ concentration ([Ca2+]i), and of the GC receptor, on that process. For this purpose, the human immature lymphoblastic CCRF-CEM cell line was used. Treatment of the cells with Dex, for up to 4 h, significantly reduced ...
Tópico(s): Immune Response and Inflammation
2002 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Brett E. Stanaland, Enrique Fernández‐Caldas, Carlos M. Jacinto, Walter L. Trudeau, Richard F. Lockey,
This study evaluated the prevalence of positive percutaneous skin test results to Blomia tropicalis, Dermatophagoides pteronyssinus, and D. farinae in 167 consecutive persons (61 males, 106 females; mean age, 38.7 years; range, 14 to 75 years) with asthma or rhinitis, or both, in Tampa, Fla. Forty-nine had asthma with or without rhinitis, and 118 had rhinitis alone. RAST and RAST inhibition analysis of all three mite species were performed by using pooled patient sera. Prepared extracts of B. tropicalis ...
Tópico(s): Insect and Pesticide Research
1994 - Elsevier BV | Journal of Allergy and Clinical Immunology
Produção Nacional
Revisado por pares
Flávio Augusto Soares Graça, Paulo Vargas Peixoto, Cleide Domingues Coelho, Saulo Andrade Caldas, Carlos Hubinger Tokarnia,
Reproduziu-se experimentalmente o envenenamento crotálico, através da inoculação, por via subcutânea, do veneno de Crotalus durissus terrificus (cascavel sul-americana) em dez bovinos mestiços. Dois animais foram utilizados como controle. O bovino que recebeu dose de 0,03mg/kg de peso corporal, morreu 7h40min após a inoculação. A dose de 0,015mg/kg causou a morte em quatro de sete bovinos inoculados, enquanto os dois animais que receberam 0,0075mg/kg adoeceram discretamente e se recuperaram. Os sintomas ...
Tópico(s): Pesticide Exposure and Toxicity
2008 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira
Produção Nacional
Revisado por pares
Ricardo J. Cassella, Daniel M. Brum, Cláudio F. Lima, Luiz Fernando S. Caldas, Carlos Eduardo R. de Paula,
This paper describes the extraction/pre-concentration of Zn from diesel oil and its determination by Flame Atomic Absorption Spectrometry (FAAS), proposed as a novel approach for these kinds of analyses and the multivariate optimization of the proposed procedure. The extraction of Zn is based on the emulsification of an aqueous solution containing Triton X-114 and HNO3 with diesel oil samples followed by breaking of the emulsion by heating. The aqueous phase obtained after the emulsion breaking was ...
Tópico(s): Pesticide Residue Analysis and Safety
2011 - Elsevier BV | Analytica Chimica Acta
Produção Nacional
A. L. Borges, Sebastião de Oliveira e Silva, Ranulfo Corrêa Caldas, Carlos Alberto da Silva Lédo,
A diagnose foliar é bastante útil na determinação do estado nutricional das plantas. As exigências nutricionais da bananeira podem diferir em função das suas características genéticas. O trabalho objetivou determinar os teores de macro e micronutrientes na terceira folha de genótipos de bananeira. Foram selecionados 24 genótipos de bananeira (triplóides e tetraplóides), em dois ciclos de produção (1999 e 2000), do Banco Ativo de Germoplasma de Banana da Embrapa Mandioca e Fruticultura Tropical, determinando- ...
Tópico(s): Plant Micronutrient Interactions and Effects
2006 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
Produção Nacional
Revisado por pares
Luiz Fernando S. Caldas, Carlos Eduardo R. de Paula, Daniel M. Brum, Ricardo J. Cassella,
A method for simple and rapid determination of Cu in petroleum-derived insulating oils used in power transformers by GFAAS is proposed in this work. The method was optimized regarding its instrumental conditions through a multivariate strategy based on the screening of the variables, to identify the significant ones, followed the application of a response surface methodology. A two-level full factorial design was employed for the screening of the variables and a four-variables Doehlert design was ...
Tópico(s): Spectroscopy and Chemometric Analyses
2012 - Elsevier BV | Fuel
Brett E. Stanaland, Enrique Fernández‐Caldas, Carlos M. Jacinto, Walter L. Trudeau, Richard F. Lockey,
BACKGROUND: Blomia tropicalis, a dust mite commonly found in subtropical and tropical environments, is the fourth most common mite in the United States. Thirty-eight percent of 167 consecutive subjects evaluated for allergic respiratory symptoms in the Tampa Bay area had positive skin test responses to B. tropicalis. METHODS: Nasal challenges were performed in 19 subjects with allergic rhinitis; 12 had positive skin test responses to B. tropicalis (group I), and seven had negative skin test responses ...
Tópico(s): Vector-borne infectious diseases
1996 - Elsevier BV | Journal of Allergy and Clinical Immunology
Ana Alemán Alemán, J. Sastre, Santiago Quirce, Manuel de las Heras, Jerónimo Carnés, Enrique Fernández‐Caldas, Carlos Pastor‐Vargas, Ana-Belén Blázquez, Fernando Vivanco, Javier Cuesta‐Herranz,
Tópico(s): Garlic and Onion Studies
2004 - Elsevier BV | Journal of Allergy and Clinical Immunology
Carlos Caldas, David Grau, Carl T. Haas,
... Collection Technologies for Real-Time Field Materials Management Carlos H. Caldas, David G. Torrent, Carl T. Haas Abstract: This ...
Tópico(s): BIM and Construction Integration
2004 - | Proceedings of the ... ISARC
Produção Nacional
Revisado por pares
Marilene Fancelli, Alex Batista Dias, Ítalo Delalibera, Sandra Cerqueira de Jesus, Antônio Souza do Nascimento, Sebastião de Oliveira e Silva, Ranulfo Corrêa Caldas, Carlos Alberto da Silva Lédo,
The objective of this study was to select strains of Beauveria bassiana for controlling Cosmopolites sordidus (Germ.) in plantain farms (cv. Terra) of the "Recôncavo" and southern regions in the state of Bahia, Brazil. The virulence of 32 B. bassiana isolates against C. sordidus was determined under laboratory conditions. Three isolates (CNPMF 407, CNPMF 218, and CNPMF 416) were selected for evaluation under field conditions in plantations located in the counties of Mutuípe and Wenceslau Guimarães. ...
Tópico(s): Insect Resistance and Genetics
2013 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Revisado por pares
Cleoni Alves Mendes de Lima, Harrison Magdinier Gomes, Maranibia Aparecida Cardoso Oelemann, Jesus Pais Ramos, Paulo Caldas, Carlos Eduardo Dias Campos, Márcia Aparecida da Silva Pereira, Fátima Fandinho Onofre Montes, Maria do Socorro Calixto de Oliveira, Philip Noël Suffys, Maria Manuela da Fonseca Moura,
The main cause of pulmonary tuberculosis (TB) is infection with Mycobacterium tuberculosis (MTB). We aimed to evaluate the contribution of nontuberculous mycobacteria (NTM) to pulmonary disease in patients from the state of Rondônia using respiratory samples and epidemiological data from TB cases. Mycobacterium isolates were identified using a combination of conventional tests, polymerase chain reaction-based restriction enzyme analysis of hsp65 gene and hsp65 gene sequencing. Among the 1,812 cases ...
Tópico(s): Tuberculosis Research and Epidemiology
2013 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Margarida Castro‐Caldas, Carlos B. Duarte, Arsélio P. Carvalho, María Celeste Lopes,
Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca 2+ ‐binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti‐inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β‐estradiol (E 2 β), on the synthesis and secretion of ANXA1 in the human CCRF‐CEM acute lymphoblastic leukemia cell line. Methods: ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2001 - Hindawi Publishing Corporation | Mediators of Inflammation
Produção Nacional
Revisado por pares
Joana Ramos Ribeiro, Luciele Cristina Pelicioni, Ilmo Caldas, Carlos Henrique Netto Lahoz, Mischel Carmen Neyra Belderrain,
The lack of technologies for space debris removal and explicit rules for the use of space are jeopardizing the future of space activities. Thus, the objective of this work was to analyse the current scientific research for space debris mitigation, prevention, monitoring and removal. We used bibliometric and patent analyses from the following databases: Space-Track, CelesTrak, Derwent and Web of Science. In this work, the scientific, technological and political actions oriented to space debris mitigation ...
Tópico(s): Planetary Science and Exploration
2018 - Elsevier BV | Space Policy
Produção Nacional
Revisado por pares
Vitor Marques Caldas, Carlos Otto Heise, João Aris Kouyoumdjian, Antônio A. Zambon, André Macedo Serafim Silva, Eduardo de Paula Estephan, Edmar Zanoteli,
Abstract This study was designed to analyze the sensitivity, specificity, and accuracy of jitter parameters combined with repetitive nerve stimulation (RNS) in congenital myasthenic syndrome (CMS), chronic progressive external ophthalmoplegia (CPEO), and congenital myopathies (CM). Jitter was obtained with a concentric needle electrode during voluntary activation of the Orbicularis Oculi muscle in CMS ( n = 21), CPEO ( n = 20), and CM ( n = 18) patients and in controls ( n = 14). RNS (3 Hz) was performed in six different muscles ...
Tópico(s): Neuroscience and Neural Engineering
2020 - Elsevier BV | Neuromuscular Disorders
Javier I. Muñoz‐González, Iván Álvarez‐Twöse, María Jara‐Acevedo, Roberta Zanotti, Cecelia Perkins, Mohamad Jawhar, Wolfgang R. Sperr, Khalid Shoumariyeh, Juliana Schwaab, Georg Greiner, Ana Henriques, Carolina Caldas, Carlos Fernández, Laura Sánchez‐Muñoz, Andrea Mayado, Alba Pérez‐Pons, Annette Schmitt‐Graeff, Justus Duyster, Ilaria Tanasi, Francesco Olivieri, Elvira Mora, Irene Luna, Leonor Senent, Maria-Helena Bañas, Amanda Núñez-García, Manuel Jurado-Chacón, Guillermo Martín-Sánchez, Enrique Colado, Blanca Xicoy, Georgina Gener-Ricós, Jason Gotlib, Patrizia Bonadonna, Andreas Reiter, Peter Valent, Andrés C. García‐Montero, Alberto Órfão,
Background Several risk stratification models have been proposed in recent years for systemic mastocytosis but have not been directly compared. Here we designed and validated a risk stratification model for progression-free survival (PFS) and overall survival (OS) in systemic mastocytosis on the basis of all currently available prognostic factors, and compared its predictive capacity for patient outcome with that of other risk scores. Methods We did a retrospective prognostic modelling study based ...
Tópico(s): Asthma and respiratory diseases
2021 - Elsevier BV | The Lancet Haematology
David Levine, Weronica E. Ek, Rui Zhang, Xinxue Liu, Lynn Onstad, Cassandra L. Sather, Pierre Lao‐Sirieix, Marilie D. Gammon, Douglas A. Corley, Nicholas J. Shaheen, Nigel C. Bird, Laura J. Hardie, Liam Murray, Brian J. Reid, Wong‐Ho Chow, Harvey A. Risch, Olof Nyrén, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H. Wu, Alan G. Casson, Stephen J. Chanock, Patricia Harrington, Isabel Caldas, Irene Debiram‐Beecham, Carlos Caldas, Nicholas K. Hayward, Paul D.P. Pharoah, Rebecca C. Fitzgerald, Stuart MacGregor, David C. Whiteman, Thomas L. Vaughan,
Thomas Vaughan and colleagues report a genome-wide association study of esophageal adenocarcinoma together with its precancerous lesion, Barrett's esophagus. They identified three loci associated with susceptibility to this cancer. Esophageal adenocarcinoma is a cancer with rising incidence and poor survival. Most such cancers arise in a specialized intestinal metaplastic epithelium, which is diagnostic of Barrett's esophagus. In a genome-wide association study, we compared esophageal adenocarcinoma ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2013 - Nature Portfolio | Nature Genetics