
Maria Clara Padoveze, Carlos Magno Castelo Branco Fortaleza, Carlos Roberto Veiga Kiffer, Afonso Luís Barth, Irna Carla do Rosário Souza Carneiro, Heloisa Ilhe Garcia Giamberardino, Jorge Luíz Nobre Rodrigues, Lauro Santos Filho, Maria Júlia Gonçalves de Mello, Milca Severino Pereira, Paulo Gontijo Filho, Mirza Rocha, Eduardo Alexandrino Sérvolo de Medeiros, Antônio Carlos Campos Pignatari,
•This study evaluated the structure for infection prevention in 153 Brazilian hospitals. •The conformity index of main structure resources was identified. •The conformity index of the infection prevention committee varied from 0.55-0.94 among hospital categories. •Most hospitals did not have a laboratory of microbiology within their premises. •The conformity index was balanced among components of the structure for infection prevention. Background Minimal structure is required for effective prevention ...
Tópico(s): Nosocomial Infections in ICU
2015 - Elsevier BV | American Journal of Infection Control
Eva Kirmeier, Lars I. Eriksson, Heidrun Lewald, Malin Jonsson Fagerlund, Andreas Hoeft, Markus W. Hollmann, Claude Meistelman, Jennifer M. Hunter, Kurt Ulm, Manfred Blobner, Alfredo Abad‐Gurumeta, Caroline Abernethy, Abigail Patrick, Kira Achaibar, Emily Adam, Arash Afshari, M. Elizabeth Agudelo Montoya, Fatma Nur Akgün, Gabriele Aletti, Neslihan Alkış, Katie Allan, Ashley Allan, Bernard Allaouchiche, Clare Allcock, Emőke Almásy, Isobel Amey, Maria Amigoni, E W Andersen, Peder Andersson, N. N. Anipchenko, Pedro E. Antunes, Earlene Armstrong, Tayyba Naz Aslam, Bjorn Aslin, José Pedro Assunção, Julia Ausserer, Mary Avvai, Nahla M. Awad, Begoña Ayas Montero, Mercedes Ayuso, Patrícia Ribeiro Azevedo, Victoria Badarau, Roxana Badescu, Martina Baiardo Redaelli, C.R.W. Baird, Yolanda Baird, Tim Baker, Packianathaswamy Balaji, Cristina Bălan, Alina Balandin, Carmen Balescu-Arion, Vilda Baliulienė, Jorge Baltasar Isabel, Saif Nasr Baluch, Daniela Bandrabur, Carla Bankewitz, Katrina Barber, Francesco Barbera, Helena Barcraft-Barnes, Valentina Barletti, Gill Barnett, Kirsty Baron, Ana Correia de Barros, Victoria Barsan, Pauline Bartlett, Chrysanthi Batistaki, Georg Baumgarten, Volkan Baytaş, Nigel Beauchamp, I.A. Becerra Cayetano, Stephanie Bell, Mattia Bellandi, Alessandro Belletti, Julio Belmonte Cuenca, Adela Benítez-Cano, Luigi Beretta, Marc Moritz Berger, Nicole Bergmann, Kristina Bergmark, María Bermúdez López, Monika Bernotaite, Charlotte J. P. Beurskens, Heena Bidd, Francesca Bifulco, Elena Bignami, Aleksandar Bilic, Diana Bilskienė, Petra Bischoff, Luke Bishop, Therese Bjonness, Hether Blaylock, Kate L. Blethyn, Thomas Blincoe, Ivan Blokhin, N Blunt, Christa Boer, Grégory Bois, Eleonora Bonicolini, Joanna Booth, Miroslawa Borecka-Kedzierska, Katarina Borstnar, Michał Borys, Emmanuel Boselli, Lionel Bouvet, R. Arthur Bouwman, Leonora Bowen, Sarah Bowrey, Leigh Boxall, Teodora Božić, Tom Bradley, Teresa Branco, Luca Brazzi, Marcella Brazzoni, Tracy Brear, N. Brogly, Farooq Brohi, Jacob Broms, Andrius Bubliauskas, Gea Erika Bucolo, Hartmut Buerkle, Donal J. Buggy, Wolfgang Buhre, Tomas Bukauskas, Francesco Butturini, Anders Byttner, Itahísa Cabrera Díaz, Adriana Calderón, Ricardo Calhau, Angel Callejo, Guy Cammu, Manuela Campesato, Özlem Selvi Can, Margarida Candeias, Andreea Cantor, Elsa Carise, Cristina Carmona, Joana Carreteiro, Cosima Carrieri, Anna Carter, M. Casal, Irene Casanova, Marco Cascella, Luis M. Casero, Guiseppina Maria Casiraghi, Laila Castelo-Branco, Carlos Castro Arranz, Daniela Cernea, Jesoporiol Cervantes, Ben Chandler, Robert Charnock, Aikaterini Chatzimicali, Elane Chinery, Ahmed Chishti, Priyakam Chondhury, Emily Christie, George Christodoudiles, Stefano Ciardo, Luminata Cimpeanu, I. Cîndea, Gilda Cinnella, Sebastian Clark, Matthew Clayton, Simona Cocu, Thomas Collyer, Carie Colvin, Sean Cope, Filomena Copeta, Sanda-Maria Copotoiu, Filinto Correia de Barros, Ruggero M. Corso, Andrea Cortegiani, Gabriela Oliveira Lobo Pereira da Costa, Amanda Cowton, Nicolas Cox, James A. Craig, V Cricca, John Cronin, M. Chollopetz da Cunha, Arturo Cuomo, Katherine Curley, Mirosław Czuczwar, Domenika Dabrowska, Sabrine Damster, Marc Danguy des Déserts, Aura Daniliuc, Thomas Danninger, Imad Darwish, Corina Dascalu, Kirsty Davies, Simon Davies, Hans D. de Boer, Adelisa De Flaviis, Gabrielle de Selincourt, Cristian Deana, B. Debaene, Gabor Debreceni, Jatin Dedhia, Isabel Delgado Garcia, Giorgio Della Rocca, Llana Delroy-Buelles, Tejal Desai, P. Dhillon, Ida Di Giacinto, P. Di Mauro, Tamara V. Diaz Gomez, Aleksandar Dimitrovski, Vesna Dinić, Dan Sebastian Dîrzu, Mona Britt Divander, Janez Dolinar, Susana Domingues, James Doolan, Charlotte Downes, Nicoleta Alice Drăgoescu, Gabriela Droc, Elisabeth Dum, A Dumitrescu, Louise Duncan, Paula Dzurňáková, Susanne Eberl, Jayne Edwards, Mark Edwards, Kim Ekelund, Patrik Ekengren, Eyad Elghouty, Richard K. Ellerkmann, Helen Ellis, Andreas Elme, Thomas Ernst, C.L. Errando, Simao Estenes, Callis Ewaldsson, Nahla Farid, James Featherstone, Daniela Febres, С. А. Федоров, Johanna Feggeler, Feijten Prisca, Tobias Fellmann, Juan Fernández Candil, Ana Fernandez Castineira, Juan Fernández Castineira, Aruna Fernando, Carlos Ferrando, Leónia Ferreira, Patrick Ferreira, Anders Christian Feyling, Daniela Filipescu, Andreas Fleischer, Leda Floris, Urs Foerster, Benjamin D. Fox, Uwe Franke, Denis Frasca, Christian Frey, Victoria Frost, Giorgio Fullin, Jacopo Fumagalli, Julie Furneval, Maurizio Fusari, Stuart Gallacher, S. V. Galushka, Giorgio Gambale, Irene Gambino, M. L. García-Pérez, Sanjeev Garg, Justyna Garlak, Željka Gavranović, Roman Gavrilov, Lames Gaynor, Agreta Gecaj-Gashi, Maria Georghiou, Bozena Gerjevic, Gudrun Gferer, Antonino Giarratano, Andrew Gibson, Vanja Gievski, Julian Giles, Lars Gillberg, Katarzyna Gilowska, Fernando Rodríguez, Antonio Gioia, Cecilia Giovannoni, Vandana Girotra, Dimitrios Gkinas, George Gkiokas, Daniela Godoroja, Ulrich Goebel, Vandana Goel, M. Velasco González, Tatjana Goranović, Ewa Górnik-Właszczuk, Smita Gosavi, peter Gottfridsson, André Gottschalk, Manuel Granell,
Summary Background Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use of neuromuscular blocking agents is associated with postoperative pulmonary complications. Methods We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in 28 European countries. We included patients (aged ≥18 years) who received ...
Elsevier BV

Raimunda Sâmia Nogueira Brilhante, Manoel de Araújo Neto Paiva, Célia Maria Souza Sampaio, Débora de Souza Collares Maia Castelo‐Branco, Carlos Eduardo Cordeiro Teixeira, Lucas Pereira de Alencar, Tereza J. P. G. Bandeira, André Jalles Monteiro, Rossana de Aguiar Cordeiro, Waldemiro Aquino Pereira-Neto, José Júlio Costa Sidrim, José Luciano Bezerra Moreira, Marcos Fábio Gadelha Rocha,
Since, there is no study reporting the mechanism of azole resistance among yeasts isolated from aquatic environments; the present study aims to investigate the occurrence of antifungal resistance among yeasts isolated from an aquatic environment, and assess the efflux-pump activity of the azole-resistant strains to better understand the mechanism of resistance for this group of drugs. For this purpose, monthly water and sediment samples were collected from Catú Lake, Ceará, Brazil, from March 2011 ...
Tópico(s): Infectious Diseases and Mycology
2016 - Springer Nature | Brazilian Journal of Microbiology

Rossana de Aguiar Cordeiro, Jonathas Sales de Oliveira, Débora de Souza Collares Maia Castelo‐Branco, Carlos Eduardo Cordeiro Teixeira, Francisca Jakelyne de Farias Marques, Paula Vago Bittencourt, Vítor Luz Carvalho, Tereza de Jesus Pinheiro Gomes Bandeira, Raimunda Sâmia Nogueira Brilhante, José Luciano Bezerra Moreira, Waldemiro de Aquino Pereira‐Neto, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha,
Candida tropicalis has been associated with invasive candidiasis, being the first or second most common non-Candida albicans Candida species isolated in humans with candidemia and candiduria, as well as being frequently isolated from healthy animals. This study aimed to characterize C. tropicalis isolates (n = 64) obtained from several animal species regarding antifungal susceptibility and production of virulence factors. The isolates were obtained from the microbiota of healthy animals (goats, n = 25; ...
Tópico(s): Fungal Infections and Studies
2014 - Oxford University Press | Medical Mycology

Raimunda Sâmia Nogueira Brilhante, Terezinha de Jesus Santos Rodrigues, Débora de Souza Collares Maia Castelo‐Branco, Carlos Eduardo Cordeiro Teixeira, Ramila de Brito Macêdo, Silviane Praciano Bandeira, Lucas Pereira de Alencar, André Jalles Monteiro, Rossana de Aguiar Cordeiro, Tereza de Jesus Pinheiro Gomes Bandeira, José Luciano Bezerra Moreira, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha,
This study aimed to identify strains of the Candida parapsilosis complex isolated from animals, as well as to assess their in vitro antifungal susceptibility profile and in vitro production of virulence attributes. We used 28 isolates of C. parapsilosis sensu lato recovered from clinically healthy animals. The strains were characterized phenotypically, followed by molecular identification of the species through PCR-restriction enzyme analysis. The susceptibility of the strains to amphotericin B, ...
Tópico(s): Infectious Diseases and Mycology
2014 - Microbiology Society | Journal of Medical Microbiology

Raimunda Sâmia Nogueira Brilhante, Lucas Pereira de Alencar, Rossana de Aguiar Cordeiro, Débora de Souza Collares Maia Castelo‐Branco, Carlos Eduardo Cordeiro Teixeira, Ramila de Brito Macêdo, Daniel Teixeira Lima, Manoel de Araújo Neto Paiva, André Jalles Monteiro, Nilza Dutra Alves, Moacir Franco de Oliveira, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha, Tereza de Jesus Pinheiro Gomes Bandeira, Terezinha de Jesus Santos Rodrigues,
There is growing interest in breeding rheas (Rhea americana) in Brazil. However, there are no data on the yeast microbiota of the gastrointestinal tract of this avian species, and the phenotypic characteristics of these yeasts are not known. Therefore, the aim of this work was to isolate Candida species from the digestive tract of rheas and to evaluate the in vitro antifungal susceptibility and secretion of phospholipases of the recovered isolates. For this purpose, 58 rheas from breeding operations ...
Tópico(s): Probiotics and Fermented Foods
2013 - Microbiology Society | Journal of Medical Microbiology

Leandro Talione Sabagh, Gustavo Luis Ferreira, Christina Wyss Castelo Branco, Carlos Frederico Duarte Rocha, Natacha Y. N. Dias,
Many species of frogs that breed in bromeliads exhibit parental care as females deposit unfertilized eggs to feed the tadpoles. Treefrogs of the genus Scinax are not known to exhibit this behavior, even though they have exotrophic tadpoles. The purpose of this study was to describe qualitatively and quantitatively the diets of tadpoles of hylids S. littoreus and S. perpusillus developing in the phytothelm of Alcantarea glaziouana (Bromeliaceae). We evaluate if there are seasonal and spatial differences ( ...
Tópico(s): Fern and Epiphyte Biology
2012 - American Society of Ichthyologists and Herpetologists | Copeia

Leandro Talione Sabagh, Roberto Júnio Pedroso Dias, Christina Wyss Castelo Branco, Carlos Frederico Duarte Rocha,
Tópico(s): Turtle Biology and Conservation
2011 - Springer Science+Business Media | Biodiversity and Conservation

Vanessa Amaral Mendonça, Luiz Cosme Cotta Malaquias, Gustavo Eustáquio Brito Alvim de Melo, Alexandre Castelo-Branco, Carlos Maurício de Figueiredo Antunes, Antônio Luiz Pinho Ribeiro, Mauro M. Teixeira, Antônio Lúcio Teixeira,
Diagnosis of leprosy is usually made clinically and there are no tests available for the routine laboratory diagnosis of the disease. The aim of this study was to investigate the potential role of chemokines as biologic markers of disease activity. We used an enzyme-linked immunosorbent assay to measure chemokines in plasma of patients with leprosy (LE) and non-infected (NI) individuals. There were significantly greater concentrations of the chemokines CCL3 and CCL11 in plasma of LE patients than ...
Tópico(s): Infectious Diseases and Tuberculosis
2007 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
... Hysterectomy with the Autosuture Stapler XAVIER IGLESIAS, CAMIL CASTELO-BRANCO, and CARLOS RIBAS3 February 2009 | Journal of Gynecologic Surgery, Vol. ...
Tópico(s): Uterine Myomas and Treatments
1992 - Mary Ann Liebert, Inc. | Journal of Gynecologic Surgery

Gabriel Reis Ferreira, José Carlos Castelo Branco Ribeiro, ALAN LIEBERSON SOUZA SILVA FILHO, Teresinha de Jesus Cardoso Farias Pereira, Daniela Moura Parente, Humberto Feitosa Pereira, Jailthon Carlos da Silva, Danielle Alves Zacarias, L. Silva, Symonara Karina Medeiros Faustino, Walfrido Salmito Almeida Neto, Dorcas Lamounier Costa, Ivete Lopes de Mendonça, Carlos Henrique Nery Costa,
Visceral leishmaniasis (VL) caused by Leishmania infantum is a lethal disease transmitted by sand flies. Although, considered a zoonosis with dogs held as the main reservoirs, humans are also sources of infection. Therefore, control policies currently focused on dog culling may need to consider that VL and human immunodeficiency virus (HIV)/VL patients may also be infectious, contributing to transmission. Reservoir competence of patients with VL without and with HIV infection and of persons asymptomatically ...
Tópico(s): Research on Leishmaniasis Studies
2017 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene

José Carlos Castelo Branco Ribeiro, Sabas Carlos Vieira, Benedito Borges da Silva, Lina Gomes dos Santos, Pedro Vitor Lopes‐Costa, Lia Andréa Costa da Fonsêca,
Female patient, 42-years-old, complaining of difficulty in urinating and swelling in the vulvar area for one year. Her gynecological examination showed extensive injury in the vulvar region and the biopsy done was inconclusive. The removal of the lesion was conducted. After the procedure, the patient remains free of recurrence for 15 months. This case highlights the need to consider angiomyxoma in the differential diagnosis for tumors of unknown cause in the vulvar region.
Tópico(s): Urological Disorders and Treatments
2015 - Instituto Israelita de Ensino e Pesquisa Albert Einstein | Einstein (São Paulo)

Carlos Magno Castelo Branco Fortaleza, Maria Clara Padoveze, Carlos Roberto Veiga Kiffer, AL Barth, Irna Carla do Rosário Souza Carneiro, H. I. G. GIAMBERARDINO, J.L.N. Rodrigues, Lauro Santos Filho, Maria Júlia Gonçalves de Mello, Milca Severino Pereira, Paulo Pinto Gontijo Filho, Michael S. Rocha, Eduardo Alexandrino Sérvolo de Medeiros, Antônio Carlos Campos Pignatari,
Healthcare-associated infections (HCAIs) challenge public health in developing countries such as Brazil, which harbour social inequalities and variations in the complexity of healthcare and regional development.To describe the prevalence of HCAIs in hospitals in a sample of hospitals in Brazil.A prevalence survey conducted in 2011-13 enrolled 152 hospitals from the five macro-regions in Brazil. Hospitals were classified as large (≥200 beds), medium (50-199 beds) or small sized ( 48 h of admission to the ...
Tópico(s): Antibiotic Use and Resistance
2017 - Elsevier BV | Journal of Hospital Infection

Sabas Carlos Vieira, Leonardo Halley Carvalho Pimentel, José Carlos Castelo Branco Ribeiro, Argemiro Ferreira de Andrade Neto, Jerúsia Oliveira Ibiapina de Santana,
CONTEXT: Meigs' syndrome consists of a benign ovarian tumor accompanied by ascites and hydrothorax. Elevated serum CA 125 levels in postmenopausal women with solid adnexal masses, ascites and pleural effusion are highly suggestive for malignant ovarian tumor. However, patients with Meigs' syndrome can also have elevated serum CA 125 levels. The authors report a case of Meigs' syndrome with elevated CA 125 level. OBJECTIVE: This is a case report of Meigs' syndrome with elevated CA 125 level. CASE ...
Tópico(s): Endometriosis Research and Treatment
2003 - Medical Association of São Paulo | Sao Paulo Medical Journal

Sheila Viana Castelo Branco Gonçalves, Carlos Henrique Nery Costa,
BACKGROUND: Pentavalent antimonials remain as the standard drugs in the treatment of cutaneous leishmaniosis. The high cost, difficult administration, long treatment time, toxicity and increasing morbidity are factors that limit the use of these drugs. OBJECTIVES: To describe the response to radiofrequency thermotherapy in the treatment of localized cutaneous leishmaniasis in Brazil, and to evaluate its safety and tolerability. METHODS: We conducted a non-comparative open trial with a total of 15 ...
Tópico(s): Insect and Pesticide Research
2018 - Elsevier BV | Anais Brasileiros de Dermatologia

Orlando José dos Santos, Jurandir Marcondes Ribas-Filho, Nicolau Gregori Czeczko, Manoel Lages Castelo Branco Neto, Carlos Naufel, Lydia Masako Ferreira, Rodrigo Peixoto Campos, Hamílton Moreira, Rafael Dib Possiedi, Samuel Dobrowolski,
OBJETIVO: Avaliar a cicatrização de ferida provocada no estômago de ratos com uso do extrato hidroalcoólico de aroeira (Schinus terebinthifolius Raddi). MÉTODOS: Foram utilizados 40 ratos, adultos, machos, divididos em dois grupos de vinte, denominados: grupo aroeira e grupo controle, cada grupo foi dividido em dois subgrupos de dez animais conforme o momento das mortes (três e sete dias). Em cada animal foi realizado o mesmo procedimento cirúrgico, ou seja, lesão do estômago e rafia com fio polipropileno ( ...
Tópico(s): Phytochemistry and biological activity of medicinal plants
2006 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira

Marcelo Adriano da Cunha e Silva Vieira, Carlos Henrique Nery Costa, José Carlos Castelo Branco Ribeiro, Lucidio Portella Nunes-Filho, Marcos Glebson Gomes Rabelo, Walfrido Salmito de Almeida-Neto,
Although cryptococcal infections begin in the lungs, meningoencephalitis is the most frequently encountered manifestation of cryptococcosis among individuals with advanced immunosuppression. As the infection progresses along the Virchow-Robin spaces, these structures may become dilated with mucoid material produced by the capsule of the organism. We report a case of a 24-year-old man with cryptococcal meningoencephalitis in which magnetic resonance imaging showed clusters of gelatinous pseudocysts ...
Tópico(s): Myasthenia Gravis and Thymoma
2013 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Mariana Fávero Bonesso, Anthony J. Yeh, Amer E. Villaruz, Hwang‐Soo Joo, Joshua W. McCausland, Carlos Magno Castelo Branco Fortaleza, Ricardo de Souza Cavalcante, Moises T. Sobrinho, Carlos Fernando Ronchi, Gordon Y. C. Cheung, M. L. R. S. Cunha, Michaël Otto,
such as hypoventilation and hypereosinophilic syndrome is surprising, and we propose that these findings may indicate novel functions for these gene products relevant to the pathogenesis of lung disease in smokers, a concept that requires further study.Our study has limitations.Subsequent functional investigation is needed to determine how these genes may contribute to the pathogenesis of complex, smoking-related acquired lung disease.This is especially true for genes whereby loss-of-function mutations ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2016 - American Thoracic Society | American Journal of Respiratory and Critical Care Medicine

Suzimar de Fátima Benato Fusco, Natiara Medolago Massarico, Maria Virgínia Martins Faria Fadul Alves, Carlos Magno Castelo Branco Fortaleza, Érika Cibele Pereira Pavan, Valéria de Castilho Palhares, Carlos Eduardo de Melo, Marla Andréia Garcia de Avila, Maria José Trevizani Nitsche,
Abstract OBJECTIVE To identify the occurrence of surgical site infection (SSI) and its risk factors in patients undergoing colon surgery in a tertiary hospital located in the countryside of the state of São Paulo. METHOD Retrospective cohort study, with collection of information contained in the medical records of patients undergoing colon surgery in the period between January 2010 and December 2013. The studied variables were the possible risk factors related to the patient, to demographic characteristics ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2016 - UNIVERSIDADE DE SÃO PAULO | Revista da Escola de Enfermagem da USP

Marcos Fábio Gadelha Rocha, Lucas Pereira de Alencar, Raimunda Sâmia Nogueira Brilhante, Jamille de Alencar Sales, Yago Brito de Ponte, Pedro Henrique de Aragão Rodrigues, Célia Maria de Souza Sampaio, Rossana de Aguiar Cordeiro, Débora de Souza Collares Maia Castelo‐Branco, Francisco Carlos de Oliveira, Francisco Geraldo Barbosa, Carlos Eduardo Cordeiro Teixeira, Manoel de Araújo Neto Paiva, Tereza de Jesus Pinheiro Gomes Bandeira, José Luciano Bezerra Moreira, José Júlio Costa Sidrim,
This study aimed to evaluate the antifungal activity of M. oleifera extracts against fungi isolated from farmed prawns and test the toxicity of the extracts on larvae of Macrobrachium amazonicum. The ethanol extracts of pods, seeds, leaves, stems and flowers and chloroform extract of flowers of M. oleifera were tested against 14 strains of Candida spp. and 10 strains of Hortaea werneckii isolated from farming water and the digestive tract of M. amazonicum. Antifungal activity was determined by microdilution, ...
Tópico(s): Aquatic life and conservation
2014 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural

Maria Carmen Arroyo Sanchez, Beatriz Julieta Celeste, José Ângelo Lauletta Lindoso, Mahyumi Fujimori, Roque Pacheco de Almeida, Carlos Magno Castelo Branco Fortaleza, Angelita Fernandes Druzian, Ana Priscila Freitas Lemos, Vanessa Campos Andrade de Melo, Anamaria Mello Miranda Paniago, Igor Thiago Queiroz, Hiro Goto,
Background The development of rK39-based immunochromatographic rapid diagnostic tests represents an important advance for serodiagnosis of visceral leishmaniasis, being cheap and easy to use at the point of care (POC). Although the use of rK39 have considerably improved the sensitivity and specificity of serological tests compared with total antigens, great variability in sensitivity and specificity was reported. This study aimed at the evaluation of "Kalazar Detect™ Rapid Test, Whole Blood" (Kalazar ...
Tópico(s): Trypanosoma species research and implications
2020 - Public Library of Science | PLoS ONE

Taisa Trevizani Rocchetti, Katheryne Benini Martins, Patrícia Yoshida Faccioli-Martins, Rogério Antônio de Oliveira, Alessandro Lia Mondelli, Carlos Magno Castelo Branco Fortaleza, Maria de Lourdes Ribeiro de Souza da Cunha,
Staphylococcus spp. - both S. aureus, including methicillin-resistant strains (MRSA) and coagulase negative staphylococci (CoNS) - are relevant agents of healthcare-associated infections. Therefore, the rapid recognition of MRSA and methicillin-resistant CoNS from blood stream infections is critically important for patient management. It is worth noting that inappropriate empiric therapy has been associated with higher in-hospital mortality.In this study we evaluated a multiplex polymerase chain reaction ( ...
Tópico(s): Bacterial biofilms and quorum sensing
2018 - Elsevier BV | The Brazilian Journal of Infectious Diseases

Fernanda Saad Rodrigues, Fernanda Avelina Clemente de Luca, Antônio Ribeiro da Cunha, Carlos Magno Castelo Branco Fortaleza,
Background Recent studies reported seasonality in healthcare-associated infections (HCAI). The association of this phenomenon with other risk factors for HCAI is not clear. Aim To analyse the interplay of season, weather and usual predictors of healthcare-associated bloodstream infections caused by Gram-negative bacilli (GNB-BSI). Methods A case-only study was conducted in a teaching hospital in Brazil. The study enrolled 446 subjects with GNB-BSI diagnosed from July 2012 to June 2016. Demographic ...
Tópico(s): Patient Satisfaction in Healthcare
2018 - Elsevier BV | Journal of Hospital Infection

Mônica da Silveira, Maria de Lourdes Ribeiro de Souza da Cunha, Camila Sena Martins de Souza, Adriana Aparecida Feltrin Correa, Carlos Magno Castelo Branco Fortaleza,
Methicillin-resistant Staphylococcus aureus poses a threat to elderly living in nursing homes. Studies focusing on the epidemiology of colonization may help in the design of infection control strategies. To identify factors associated with MRSA colonization and the dissemination of clones among nursing home residents. Nasal swabs were collected from 300 persons from nine nursing homes in the city of Bauru, Brazil. Resistance to methicillin was identified through amplification of the mecA gene. Strain ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2018 - BioMed Central | Annals of Clinical Microbiology and Antimicrobials

Guilherme Giacomini, Ana Luiza Menegatti Pavan, João Maurício Carrasco Altemani, S. B. Duarte, Carlos Magno Castelo Branco Fortaleza, José Ricardo de Arruda Miranda, Diana Rodrigues de Pina,
Volume measurements of maxillary sinus may be useful to identify diseases affecting paranasal sinuses. However, literature shows a lack of consensus in studies measuring the volume. This may be attributable to different computed tomography data acquisition techniques, segmentation methods, focuses of investigation, among other reasons. Furthermore, methods for volumetrically quantifying the maxillary sinus are commonly manual or semiautomated, which require substantial user expertise and are time- ...
Tópico(s): Dental Radiography and Imaging
2018 - Public Library of Science | PLoS ONE

Eliane Patrícia Lino Pereira-Franchi, Maria Rachel Nogueira Barreira, Natália de Sousa Lima Moreira da Costa, Carlos Magno Castelo Branco Fortaleza, Maria de Lourdes Ribeiro de Souza da Cunha,
Wounds can be colonized by methicillin-resistant Staphylococcus aureus (MRSA).We evaluated the prevalence of S. aureus and MRSA in the wounds of patients treated at Basic Health Units in Brazil and identified risk factors associated with their presence.The prevalence rates of S. aureus and MRSA were 51.5% and 8.7%, respectively. There was a correlation between the presence of S. aureus in wounds and nostrils (p<0.01). A positive association was detected between S. aureus infection and previous benzylpenicillin ...
Tópico(s): Surgical site infection prevention
2017 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Aydir Cecília Marinho Monteiro, Carlos Magno Castelo Branco Fortaleza, Adriano Martison Ferreira, Ricardo de Souza Cavalcante, Alessandro Lia Mondelli, Eduardo Bagagli, Maria de Lourdes Ribeiro de Souza da Cunha,
Bloodstream infections are responsible for thousands of deaths each year. The rapid identification of the microorganisms causing these infections permits correct therapeutic management that will improve the prognosis of the patient. In an attempt to reduce the time spent on this step, microorganism identification devices have been developed, including the VITEK® 2 system, which is currently used in routine clinical microbiology laboratories. This study evaluated the accuracy of the VITEK® 2 system ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2016 - BioMed Central | Annals of Clinical Microbiology and Antimicrobials

Mariana Gatto, Mariana Miziara de Abreu, Karen Ingrid Tasca, Márjorie de Assis Golim, Laura Denise Mendes da Silva, José Cláudio Simão, Carlos Magno Castelo Branco Fortaleza, Ângela Maria Victoriano de Campos Soares, Sueli Aparecida Calvi,
Toll-like receptors (TLRs) have significant involvement in Leishmania infection, although little is known about the relationship between these receptors, cytokines and nitric oxide (NO) in patients with visceral leishmaniasis (VL) before or after treatment with anti-leishmanial drugs. The goal of this study was to evaluate the expression of TLR2 and TLR4 in CD3+ and CD14+ cells and the production of TNF-α, IFN-γ, IL-17, IL-10, TGF-β and NO in peripheral blood mononuclear cells (PBMCs) from VL patients ...
Tópico(s): Urticaria and Related Conditions
2015 - Public Library of Science | PLoS ONE

Geraldine Madalosso, Carlos Magno Castelo Branco Fortaleza, Ana Freitas Ribeiro, Lisete Lage Cruz, Péricles Alves Nogueira, José Ângelo Lauletta Lindoso,
Objectives . To identify factors associated with death in visceral leishmaniasis (VL) cases. Patients and Methodology . We evaluated prognostic factors for death from VL in São Paulo state, Brazil, from 1999 to 2005. A prognostic study nested in a clinical cohort was carried out by data analysis of 376 medical files. A comparison between VL fatal cases and survivors was performed for clinical, laboratory, and biological features. Association between variables and death was assessed by univariate analysis, ...
Tópico(s): Research on Leishmaniasis Studies
2012 - Hindawi Publishing Corporation | Journal of Tropical Medicine

Carlos Magno Castelo Branco Fortaleza, Fernanda Moreira de Freitas, Gerhard da Paz Lauterbach,
We studied a nonconcurrent cohort of 582 patients admitted to a medical-surgical intensive care unit. Use of antimicrobials (imipenem and metronidazole) was a risk factor for acquisition of imipenem-resistant Acinetobacter baumannii only for the subcohort of patients admitted in months in which colonization pressure was lower than the median value.
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2012 - Elsevier BV | American Journal of Infection Control