Giles Smith, Andrew Robson, Catherine Riley, Lawrence T. Roach, Frances Gibb Legal Editor, Gary Duncan, Simon Barnes, Elizabeth Judge and Jenny Davey, Paul Hoggart, Austin Baker, Ivo Tennant, Philip Howard, Katie Scott, Hilary Finch, Shaka Hislop, Richard Ford, Greg Hurst and Dominic Kennedy, David Irvine, Michael Binyon, Joanna Bale, Rachel Campbell-Johnston, Penny Wark, Clive Davis, Alexandra Frean Social Affairs Correspondent, Elizabeth Judge, Gabrielle Starkey, Rosemary Bennett and David Maxwell, Lorraine Eames, Kevin Eason, Geoff Brown, Joe Joseph, Ralph Kenber, Bishop Dr John, Ben Webster Transport Correspondent, Pat Gibson, Valerie Elliott Countryside Editor, Tom Hawkins, Johan Wennstrom, Dominic Walsh, Will Pavia and Alex Frean, Sajjad Karim, MEP, Don Campbell, Dr D. R. Cooper, Jill Dupleix, Daniel Finkelstein, Richard Ford Home Correspondent, Stephen Farrell, Sir Geoff Hurst, Jenny MacArthur, Anatole Kaletsky, Christine Broadbent, David Hands, Graham Keeley, Adam Sherwin Media Correspondent, Mark Pougatch, Matt Dickinson Chief Football Correspondent, Stefanie Marsh, Danny Kelly, Russell Kempson, Gary Duncan Economics Editor, Oliver Kay, Rick Broadbent, Charles H. Rieper, Tom Baldwin, Rob Wright, Geoffrey Dean, Gabriel Rozenberg, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Marcus Binney, Raymond Keene, Gianluca Vialli, Matthew Pryor, Matt Hughes, Rebecca O'Connor, Bruce Dessau, David Bean, Dr Tanya Byron, Kaveh Solhekol, Matthew Green, Caroline Merrell, Neville Scott, Fran Yeoman, Oliver James, Kate Rew, Damian Whitworth, Peter Dixon, Ned Parker, David Hands Rugby Correspondent, Tony Cascarino, Paul Simons, Dr Arnold Holtzman, William Rees-Mogg, Dominic Kennedy, George Bird, Tim Hames, Raymond Keene and Alan Hamilton, Craig Lord, Michele Kirsch, Ian Johns, Dominic Maxwell, Anjana Ahuja, George Caulkin, Caitlin Moran, Martin A. Locke, Alan Lee, David Elleray, Mark Eklid, Alan Shearer, Brian Glanville, David Sanderson, Jack Malvern Arts Reporter, Mark Henderson, Catherine Philp, Lisa Verrico, Danny Baker, Sarah Butler, James Baldwin, Brad Gilbert, Dr Thomas Stuttaford, Stephen Dalton, David Powell, Richard Morrison, Philip Hodson, Paul Tyrer, Bill Edgar, Marcus Oscarsson and Jacqui Goddard, Valerie Grove, Owen Slot, Olav Bjortomt, Jenny Davey, Nicola Copping, Richard Ford, Sam Lister Health Correspondent, Stephanie Switzer, Joe Bolger, Christopher Irvine, Stephen Pollard,
... in the heat Fifa Vexed by Shadow Play Carlos Gamarra's Own Goal in the Third Minute for ...
2006 - Gale Group | TDA
Stacy L. Wempe, Carlos Gamarra‐Luques, Carlos Telleria,
We have previously shown that the antiprogestin and antiglucocorticoid mifepristone inhibits the growth of ovarian cancer cells. In this work, we hypothesized that cellular stress caused by mifepristone is limited to cytostasis and that cell killing is avoided as a consequence of the persistent activity of the PI3K/Akt survival pathway. To investigate the role of this pathway in mifepristone-induced growth inhibition, human ovarian cancer cells of various histological subtypes and genetic backgrounds ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2013 - SAGE Publishing | Cancer Growth and Metastasis
Gonzalo Larrabure, Sheyla Chero-Osorio, Dhamelyz Silva-Quiñones, Carsten Benndorf, Mackenzie G. Williams, Fei Gao, Carlos Gamarra, Alejandro Alarcón, Carlos Segura, Andrew V. Teplyakov, Juan Carlos F. Rodríguez-Reyes,
Leaching of polymetallic sulfides is often challenging due to the complexity of these systems. The main issues are related to the formation of surface by-products or to the presence of different metals that require a greater consumption of chemicals compared to that needed to extract the target metal during leaching. This latter case is followed in the present work using X-ray photoelectron spectroscopy (XPS) during the leaching of a silver-containing polymetallic (Mn-Fe-Pb) sulfide under three different ...
Tópico(s): Minerals Flotation and Separation Techniques
2020 - Elsevier BV | Hydrometallurgy
Produção Nacional
Revisado por pares
Tatiana Taís Sibov, Patrícia Severino, Luciana Cavalheiro Marti, Lorena Favaro Pavon, Daniela Mara de Oliveira, Patrícia Renovato Tobo, Alexandre Holthausen Campos, Ângela Tavares Paes, Edson Amaro, Lionel Fernel Gamarra, Carlos Alberto Moreira‐Filho,
Isolation of mesenchymal stem cells (MSCs) from umbilical cord blood (UCB) from full-term deliveries is a laborious, time-consuming process that results in a low yield of cells. In this study we identified parameters that can be helpful for a successful isolation of UCB-MSCs. According to our findings, chances for a well succeeded isolation of these cells are higher when MSCs were isolated from UCB collected from normal full-term pregnancies that did not last over 37 weeks. Besides the duration of ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2012 - Springer Science+Business Media | Cytotechnology
Karin Bartl, Jorge Gamarra, Carlos Gómez, H.‐R. Wettstein, M. Kreuzer, Hans Heß,
Abstract The agronomic performance and nutritive value of twelve annual and perennial grasses and legumes were analysed in order to define alternatives to local forages for dry‐season feeding of ruminants in the Peruvian Andes. There were twelve species and two fertilizer treatments (no fertilizer and a N;P;K fertilizer mainly applied at sowing) in an experiment with a randomized complete block design with three replicates at each of two sites. Plant height, soil cover by forage and weed species, ...
Tópico(s): Plant Taxonomy and Phylogenetics
2009 - Wiley | Grass and Forage Science
J. Armando Gamarra, Carlos Cuevas, Gerardo Lescano,
A stirred catalytic basket reactor with immobilized yeast cells was used for the batchwise production of ethanol. Fractional conversions up to 0.99 in 10 h were attained, depending on the agitation rates, initial glucose, and cell densities. The volumetric productivity of the reactor was considerably better than that of conventional stirred tank reactors. Productivities were strongly dependent on the stirred speed.
Tópico(s): Microbial Metabolic Engineering and Bioproduction
1986 - Elsevier BV | Journal of Fermentation Technology
Carlos Gamarra‐Luques, María Belén Hapon, Alicia A. Goyeneche, Carlos M. Telleria,
Antiprogestin compounds have been shown to be effective in blocking the growth of ovarian cancer cells of different genetic backgrounds. Herein we studied the anti-ovarian cancer effect of a series of antiprogestins sharing the chemical backbone of the most characterized antiprogestin, mifepristone, but with unique modifications in position C-17 of the steroid ring. We assessed the effect of mifepristone-like antiprogestins on the growth of ovarian cancer cells sensitive to the standard combination ...
Tópico(s): Reproductive System and Pregnancy
2014 - BioMed Central | Journal of Ovarian Research
Carlos Gamarra‐Luques, Alicia A. Goyeneche, María Belén Hapon, Carlos Telleria,
Abstract Background Advanced ovarian cancer is treated with cytoreductive surgery and combination platinum- and taxane-based chemotherapy. Although most patients have acute clinical response to this strategy, the disease ultimately recurs. In this work we questioned whether the synthetic steroid mifepristone, which as monotherapy inhibits the growth of ovarian cancer cells, is capable of preventing repopulation of ovarian cancer cells if given after a round of lethal cisplatin-paclitaxel combination ...
Tópico(s): Microtubule and mitosis dynamics
2012 - BioMed Central | BMC Cancer
Rafael Valle‐Oñate, Liliana Candia, Consuelo Romero‐Sánchez, Pedro Santos-Moreno, Carlo V. Caballero‐Uribe, Antonio Iglesias Gamarra, Carlo V. Caballero‐Uribe, John Londoño,
There are no formal statistics about the incidence, prevalence or demographics of patients with spondyloarthropathies (SpAs) in colombia. However, information from a few studies provides a preliminary snapshot of SpAs in the country. In this article, the authors review what has been published; document what their group is doing and outline what they still need to do in the future. The analysis suggests that although information on SpA in Colombia is limited, it is known that the diagnostic entities ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2011 - Elsevier BV | The American Journal of the Medical Sciences
Lei Zhang, María Belén Hapon, Alicia A. Goyeneche, Rekha Srinivasan, Carlos Gamarra‐Luques, Eduardo Callegari, Donis D. Drappeau, Erin J Terpstra, Bo Pan, Jennifer R. Knapp, Jeremy Chien, Xuejun Wang, Kathleen M. Eyster, Carlos Telleria,
The synthetic steroid mifepristone blocks the growth of ovarian cancer cells, yet the mechanism driving such effect is not entirely understood. Unbiased genomic and proteomic screenings using ovarian cancer cell lines of different genetic backgrounds and sensitivities to platinum led to the identification of two key genes upregulated by mifepristone and involved in the unfolded protein response (UPR): the master chaperone of the endoplasmic reticulum (ER), glucose regulated protein (GRP) of 78 kDa, ...
Tópico(s): Calcium signaling and nucleotide metabolism
2016 - Elsevier BV | Molecular Oncology
Hanaa Talei, Driss Benhaddou, Carlos Gamarra, Houda Benbrahim, Mohamed Essaaidi,
The climate of Houston, classified as a humid subtropical climate with tropical influences, makes the heating, ventilation, and air conditioning (HVAC) systems the largest electricity consumers in buildings. HVAC systems in commercial buildings are usually operated by a centralized control system and/or an energy management system based on a fixed schedule and scheduled control of a zone setpoint, which is not appropriate for many buildings with changing occupancy rates. Lately, as part of energy ...
Tópico(s): Energy Load and Power Forecasting
2021 - Multidisciplinary Digital Publishing Institute | Energies
Carlos Gamarra, Jennifer Ronk,
Texas is experiencing tremendous growth, which puts pressure on resources including water and electricity supplies. Texas leads the nation in renewable energy production and is experiencing tremendous growth in the solar energy sector, with the Solar Energy Industries Association reporting that Texas is on track to become the fastest growing utility-scale solar market in the United States within the next five years. In this market, a new photovoltaic (PV) technology, floating solar, is gaining attention. ...
Tópico(s): Solar Radiation and Photovoltaics
2019 - | Texas Water Journal
Jessica Gómez, Mario J. Simirgiotis, Beatriz Lima, Carlos Gamarra‐Luques, Jorge Bórquez, Duilio Caballero, Gabriela E. Feresin, Alejandro Tapia,
The decoction of Tessaria absinthioides is used in traditional medicine of South America as hypocholesterolemic, balsamic, and expectorant; but it is also useful for the prevention of hepatitis, renal insufficiency, and diabetes, and is used as digestive. A lyophilized decoction from the aerial parts of this plant (TLD) collected in San Juan (TLDSJ) and Mendoza (TLDM) provinces (Argentina) and one collection from Antofagasta, Chile (TLDCH) were characterized regarding antioxidant and antibacterial activities, ...
Tópico(s): Natural product bioactivities and synthesis
2019 - Multidisciplinary Digital Publishing Institute | Antioxidants
Produção Nacional
Revisado por pares
Jorge Marcos Rosa, Elias Basile Tambourgi, Rosângela Maria Vanalle, Félix Martin Carbajal Gamarra, José Carlos Curvelo Santana, Maurício de Campos Araújo,
Traditional textile wastewater treatment methods are inefficient and consequently pollute the environment. Thus, the use of new and efficient wastewater treatment techniques should be encouraged, such Advanced Oxidative Process (AOP), that is a fast and effective technique in the degradation of contaminants, which use strong oxidising agents in the degradation of organic contaminants, forming mainly into CO2 and water. This work aimed to apply H2O2/UV advance oxidative process (AOP) as an alternative ...
Tópico(s): Advanced oxidation water treatment
2019 - Elsevier BV | Journal of Cleaner Production
Jessica Gómez, Mario J. Simirgiotis, Beatriz Lima, Jésica Daniela Paredes, Carlos M. Villegas Gabutti, Carlos Gamarra‐Luques, Jorge Bórquez, Lorena Luna, Graciela Haydée Wendel, Alejandra María, Gabriela E. Feresin, Alejandro Tapia,
The decoction of the local plant Baccharis grisebachii is used as a digestive, gastroprotective, external cicatrizing agent and antiseptic in Argentine. A lyophilized decoction (BLD) from the aerial parts of this plant was evaluated regarding its anti-ulcer, antioxidant and cytotoxic activities and the bioactivities were supported by UHPLC-MS metabolome fingerprinting which revealed the presence of several small bioactive compounds. The antioxidant properties were evaluated by DPPH, TEAC, FRAP and ...
Tópico(s): Phytochemicals and Antioxidant Activities
2019 - Multidisciplinary Digital Publishing Institute | Molecules
Carlos Gamarra, Josep M. Guerrero, Eduardo Montero,
The progressive application of Information and Communication Technologies to industrial processes has increased the amount of data gathered by manufacturing companies during last decades. Nowadays some standardized management systems, such as ISO 50.001 and ISO 14.001, exploit these data in order to minimize the environmental impact of manufacturing processes. At the same time, microgrid architectures are progressively being developed, proving to be suitable for supplying energy to continuous and ...
Tópico(s): IoT and Edge/Fog Computing
2016 - Elsevier BV | Renewable and Sustainable Energy Reviews
Carlos Gamarra, Josep M. Guerrero,
Microgrids are expected to become part of the next electric power system evolution, not only in rural and remote areas but also in urban communities. Since microgrids are expected to coexist with traditional power grids (such as district heating does with traditional heating systems), their planning process must be addressed to economic feasibility, as a long-term stability guarantee. Planning a microgrid is a complex process due to existing alternatives, goals, constraints and uncertainties. Usually ...
Tópico(s): Hybrid Renewable Energy Systems
2015 - Elsevier BV | Renewable and Sustainable Energy Reviews
S. Marti-Alamo, A. Mancheno-Franch, C. Marzal-Gamarra, L. Carlos-Fabuel,
There is a growing interest in diagnosis based on the analysis of saliva.This is a simple, non-invasive method of obtaining oral samples which is safe for both the health worker and the patient, not to mention allowing for simple and cost-efficient storage.The majority of studies use general saliva samples in their entirety, complex fluids containing both local and systemic sources and whose composition corresponds to that of the blood.General saliva contains a considerable amount of desquamated ...
Tópico(s): Thyroid Disorders and Treatments
2012 - Medicina Oral S.L. | Journal of Clinical and Experimental Dentistry
María Belén Hapon, Carlos Gamarra‐Luques, Graciela A. Jahn,
Abstract Background Rats made hypothyroid with propilthyouracil start showing abnormal cycling on the second cycle after the start of the treatment, with a high proportion of spontaneous pseudopregnancies and reduced fertility. Methods To investigate some of the mechanisms involved in these reproductive abnormalities, hypothyroidism was induced in virgin rats by propilthyouracil (0.1 g/L in the drinking water) and we determined circulating hormones by radioimmunoassay and whole ovary expression of ...
Tópico(s): Birth, Development, and Health
2010 - BioMed Central | Reproductive Biology and Endocrinology
Maximiliano Giraud‐Billoud, Eduardo Koch, Israel A. Vega, Carlos Gamarra‐Luques, Alfredo Castro‐Vazquez,
Intracellular urate concretions are known to occur in some insects, crustaceans and gastropods. Crystalloid-containing urate cells and tissues are widespread in many organs of the apple-snail Pomacea canaliculata. The occurrence of three different urate tissues (perivascular, compact and nodular) correlated well with uric acid concentrations found in the organs containing them. The highest uric acid concentrations were found in the coiled gut (showing both perivascular and compact tissues), the style ...
Tópico(s): Mercury impact and mitigation studies
2008 - Oxford University Press | Journal of Molluscan Studies
Israel A. Vega, Carlos Gamarra‐Luques, Eduardo Koch, Leonardo E. Bussmann, Alfredo Castro‐Vazquez,
Tópico(s): Paleopathology and ancient diseases
2005 - Springer Science+Business Media | Symbiosis
Fabio Andrés Persia, Estefanía Rinaldini, Hapon MB, Carlos Gamarra‐Luques,
Secondary plant metabolites are regarded as promising sources of plant-protecting substances and they are one of the most important lines of plant defense against pests.The range of cellular targets for these substances is very wide and covers metabolic pathways, macromolecules and organelles.In consequence, the plant derivatives study represents a critical situation in which toxic effects against other organisms need to be evaluated in relation to its biological benefits.The genus Prosopis (Fabaceae) ...
Tópico(s): Essential Oils and Antimicrobial Activity
2016 - OMICS Publishing Group | Journal of Clinical Toxicology
Fabio Andrés Persia, Mariana Troncoso, Estefanía Rinaldini, Mario J. Simirgiotis, Alejandro Tapia, Jorge Bórquez, Juan Pablo Mackern‐Oberti, María Belén Hapon, Carlos Gamarra‐Luques,
The aqueous extract of the Argentinean native plant, Prosopis strombulifera (PsAE), presents cytotoxicity against human cancer cell lines by inducing cytostasis, necrosis and apoptosis; with diminution of clonogenic survival; without genotoxic effects nor oral animal toxicity. Until now, the chemical extract composition and its in vivo antitumoral properties remain unknown; these studies are the aim of the current work. The PsAE was characterized by chemical fingerprinting and the metabolome was ...
Tópico(s): Phytochemical Studies and Bioactivities
2020 - Elsevier BV | Heliyon
Carlos Gamarra‐Luques, Maximiliano Giraud‐Billoud, Alfredo Castro‐Vazquez,
The complex array of male and female reproductive organs in Pomacea canaliculata develops from the gonoductal and copulatory primordia. These primordia are present in both sexes, but while the gonoductal primordium (or 'gonoduct') is present in hatchlings, the copulatory primordium only appears in juveniles at the 5-mm (shell length) stage. The proximal portion of the gonoduct will produce the gonad, while the more distal portions will produce the accessory sexual organs (the visceral vas deferens, ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2013 - Oxford University Press | Journal of Molluscan Studies
Carlos Gamarra‐Luques, Israel A. Vega, Eduardo Koch, Alfredo Castro‐Vazquez,
A new species of cyclopoid copepod, Ozmana huarpium , is described as a symbiont to Pomacea canaliculata (Lamarck 1822) (Caenogastropoda, Ampullariidae). Rather large numbers (about one hundred copepods per snail) were found, although there was no evidence of harm to the host. To our knowledge, O. haemophila (symbiont to P. maculata ), and the currently described species, O. huarpium , are the only copepod species ever recorded as endosymbionts to freshwater invertebrates. While O. haemophila is restricted ...
Tópico(s): Parasite Biology and Host Interactions
2004 - | Biocell
Beatriz C. Winik, Marta Catalán, Carlos Gamarra‐Luques, Alfredo Castro‐Vazquez,
Abstract. Pomacea canaliculata is an internally fertilizing gastropod that produces, besides fertilizing sperm (=eusperm), a large number of unfertile sperm (=parasperm) that have no chromatin, are fusiform, and have three to five flagella. Here, we report that this snail also produces another type of parasperm, which results from a peculiar spermiogenesis including an anterior cytoplasmic migration. The mature oligopyrene parasperm has: (1) a rounded head including a partly lysed nucleus, (2) a conical ...
Tópico(s): Marine Biology and Ecology Research
2009 - Wiley | Invertebrate Biology
Virna Margarita Martín Giménez, Marcos G. Russo, Griselda E. Narda, Lucía B. Fuentes, Luciana Mazzei, Carlos Gamarra‐Luques, Diego Kassuha, Walter Manucha,
Drug encapsulation in nanocarriers such as polymeric nanoparticles (Nps) may help to overcome the limitations associated with cannabinoids. In this study, the authors' work aimed to highlight the use of electrospraying techniques for the development of carrier Nps of anandamide (AEA), an endocannabinoid with attractive pharmacological effects but underestimated due to its unfavourable physicochemical and pharmacokinetic properties added to its undesirable effects at the level of the central nervous ...
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2019 - Institution of Engineering and Technology | IET Nanobiotechnology
Maximiliano Giraud‐Billoud, Carlos Gamarra‐Luques, Alfredo Castro‐Vazquez,
Tópico(s): Space Exploration and Technology
2012 - Springer Science+Business Media | Zoomorphology
Juan Sebastián Gamarra Quintero, Carlos Alirio Díaz González, Leonardo Pacheco Sandoval,
Tópico(s): Thermodynamic and Exergetic Analyses of Power and Cooling Systems
2021 - Elsevier BV | Sustainable Energy Technologies and Assessments
Vivencio Barrios, Carlos Escobar, Javier Gamarra, Juan Carlos Obaya, Vicente Pallarés‐Carratalá,
Conocer la opinión de los médicos sobre los criterios diagnósticos, objetivos de control, grado de control y manejo terapéutico del paciente con dislipidemia en España. Se creó un cuestionario específico sobre criterios diagnósticos, objetivos de control, grados de control, tratamientos hipolipemiantes e inercia terapéutica en el paciente con dislipidemia. Los profesionales registraron las respuestas online durante un período de cuatro meses. Se recogieron cuestionarios de 959 profesionales de toda ...
Tópico(s): Pharmaceutical Economics and Policy
2020 - Elsevier BV | Medicina de Familia SEMERGEN