Beatriz Navascués, Javier Bartolome Calvo, Gema Morales, Carlos Santos Burguete, Alfons Callado, Alberto Cansado, Joan Cuxart, Margarita Diez, P. del Río, Pau Escribà, O. García-Colombo, José Antonio García-Moya, Carlos Geijo, Eliana Alviárez Gutierrez, Mariano Hortal, Isabel Martínez Marco, B. Orfila, José Antonio Parodi, Ernesto Rodríguez Camino, Jana Sánchez Arriola, Inés Santos-Atienza, Juan Simarro,
The evolution of Numerical Weather Prediction (NWP) activities at the Spanish State Meteorological Agency (AEMET) is reviewed not only for historical reasons but mainly to demonstrate the value added by Limited Area Models to deterministic and probabilistic short range forecasting. This paper highlights the decisive role of international cooperation in the general progress achieved by the NWP area of research. In fact, most of the activities here described have taken place in collaboration with the ...
Tópico(s): Wind and Air Flow Studies
2013 - Elsevier BV | Atmospheric Research
Virginia Sedeño-Monge, Raúl Arcega-Revilla, Emmanuel Rojas-Morales, Gerardo Santos‐López, Juan Carlos Pérez-García, Francisca Sosa-Jurado, Verónica Vallejo‐Ruiz, Casandra Lucrecia Solis-Morales, Salvador Aguilar-Rosas, Julio Reyes‐Leyva,
Multiple sclerosis (MS) is an autoimmune disease characterized by a triad of inflammation, demyelination and gliosis. Because the suppressors of cytokine signaling (Socs) regulate the immune response, we quantified SOCS1 and SOCS3 transcription in peripheral blood leukocytes of patients with MS. SOCS1 transcription decreased significantly in MS patients compared with neurologically healthy persons (0.08±0.02 vs. 1.02±0.23; p=0.0001); while SOCS3 transcription increased in MS patients compared with ...
Tópico(s): NF-κB Signaling Pathways
2014 - Elsevier BV | Journal of Neuroimmunology
Raquel Mejías, R. Costo, Alejandro G. Roca, Cristina Fernańdez-Arias, S. Veintemillas‐Verdaguer, T. González-Carreño, M. P. Morales, Carlos J. Serna, Santos Mañes, Domingo F. Barber,
Attachment of cytokines to magnetic nanoparticles has been developed as a system for controlled local drug release in cancer therapy. We studied the adsorption/release of murine interferon gamma (IFN-γ) on negatively charged magnetic nanoparticles prepared by three different methods, including coprecipitation , decomposition in organic media, and laser pyrolysis. To facilitate IFN-γ adsorption, magnetic nanoparticles were surface modified by distinct molecules to achieve high negative charge at pH ...
Tópico(s): Immunotherapy and Immune Responses
2008 - Elsevier BV | Journal of Controlled Release
Phoenix Toboz, Mehdi Amiri, Negar Tabatabaei, Catherine R. Dufour, Seung Hyeon Kim, Carine Fillebeen, Charles Ayemoba, Arkady Khoutorsky, Manfred Nairz, Lijian Shao, Kostandin V. Pajcini, Ki-Wook Kim, Vincent Giguère, Regiana L. Oliveira, Marco Constante, Manuela M. Santos, Carlos R. Morales, Kostas Pantopoulos, Nahum Sonenberg, Sandra Pinho, Soroush Tahmasebi,
GCN2 (general control nonderepressible 2) is a serine/threonine-protein kinase that controls messenger RNA translation in response to amino acid availability and ribosome stalling. Here, we show that GCN2 controls erythrocyte clearance and iron recycling during stress. Our data highlight the importance of liver macrophages as the primary cell type mediating these effects. During different stress conditions, such as hemolysis, amino acid deficiency or hypoxia, GCN2 knockout ( GCN2 −/− ) mice displayed resistance ...
Tópico(s): RNA regulation and disease
2022 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Eduardo Pérez-Gómez, María Villa‐Morales, Javíer Santos, José Fernández‐Piqueras, Carlos Gamallo, Javier Dotor, Carmelo Bernabéu, Miguel Quintanilla,
Abstract Endoglin is a membrane glycoprotein that acts as a coreceptor for transforming growth factor-β. We and others have previously suggested a function of endoglin as a tumor suppressor in epithelial cancer. Here, we study the expression of endoglin during chemical mouse skin carcinogenesis. We find that shedding of membrane endoglin, allowing the secretion of a soluble endoglin form, is a late event associated with progression from squamous to spindle cell carcinomas. Knockdown of endoglin ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2007 - American Association for Cancer Research | Cancer Research
Sofía T. Menéndez, Verónica Rey, Lucia Martinez‐Cruzado, Marı́a Victoria González, Álvaro Morales‐Molina, Laura Santos, Verónica Blanco, Carlos Álvarez-Fernández, Óscar Estupiñán, Eva Allonca, Juan P. Rodrigo, Javier García‐Castro, Juana M. García‐Pedrero, René Rodrı́guez,
Stemness in sarcomas is coordinated by the expression of pluripotency factors, like SOX2, in cancer stem cells (CSC). The role of SOX2 in tumor initiation and progression has been well characterized in osteosarcoma. However, the pro-tumorigenic features of SOX2 have been scarcely investigated in other sarcoma subtypes. Here, we show that SOX2 depletion dramatically reduced the ability of undifferentiated pleomorphic sarcoma (UPS) cells to form tumorspheres and to initiate tumor growth. Conversely, ...
Tópico(s): Cancer Genomics and Diagnostics
2020 - Multidisciplinary Digital Publishing Institute | Cancers
Hélder A. Santos, Vladimir García‐Morales, Carlos M. Pereira,
Biomembrane models built at the interface between two immiscible electrolytes (ITIES) are useful systems to study phenomena of biological relevance by means of their electrochemical processes. The unique properties of ITIES allow one either to control or measure the potential difference across the biomimetic membranes. Herein we focus on phospholipid monolayers adsorbed at liquid-liquid interfaces, and besides discussing recent developments on the subject, we describe electrochemical techniques that ...
Tópico(s): Electrochemical Analysis and Applications
2009 - Wiley | ChemPhysChem
José Miguel Morales‐Asencio, Francisco Javier Martín‐Santos, Shakira Kaknani, Juan Carlos Morilla Herrera, Magdalena Cuevas Fernández‐Gallego, Silvia García‐Mayor, Álvaro León‐Campos, Isabel María Morales‐Gil,
Abstract Rationale, aims and objectives Case management is commonly used to provide health care for patients with multiple chronic conditions. However, the most effective form of team organization and the necessary support structures need to be identified. In this respect, patients' views could provide a valuable contribution to improving the design of these services. To analyse the experiences of patients with chronic diseases and of caregivers, in relation to health care services and mechanisms, ...
Tópico(s): Diabetes Management and Education
2014 - Wiley | Journal of Evaluation in Clinical Practice
José Miguel Morales‐Asencio, Francisco Javier Martín‐Santos, Juan Carlos Morilla Herrera, Magdalena Cuevas Fernández‐Gallego, Miriam Celdrán-Mañas, Francisco Javier Navarro-Moya, María del Mar Rodríguez Salvador, Francisco J Muñoz-Ronda, Elena Gonzalo-Jiménez, Almudena Millán Carrasco,
Chronic diseases account for nearly 60% of deaths around the world. The extent of this silent epidemic has not met determined responses in governments, policies or professionals in order to transform old Health Care Systems, configured for acute diseases. There is a large list of research about alternative models for people with chronic conditions, many of them with an advanced practice nurse as a key provider, as case management. But some methodological concerns raise, above all, the design of ...
Tópico(s): Nursing care and research
2010 - BioMed Central | BMC Health Services Research
Jans Alzate‐Morales, William Tiznado, Juan C. Santos, Carlos Cárdenas, Renato Contreras,
We report a theoretical study on a series of CDK2 inhibitors using a set of global reactivity indices defined in terms of the density of states. The statistical analysis was performed on the basis of two groups of 11 and 6 compounds, respectively, reported by Hardcastle et al. (J. Med. Chem. 2004, 47, 3710−3722). Both series were classified on the basis of the correlations obtained for the complete set of compounds and the sites targeted within the active site of CDK2. The comparison between the ...
Tópico(s): Advanced Chemical Physics Studies
2007 - American Chemical Society | The Journal of Physical Chemistry B
José Miguel Morales‐Asencio, Elena Gonzalo Jiménez, Francisco Martín Santos, Juan Carlos Morilla Herrera, Javier Terol Fernández, Carmen Ruiz Barbosa,
La incertidumbre preside la práctica clínica de los profesionales sanitarios, fenómeno al que no permanecen ajenas las enfermeras. La toma de decisiones es una de las principales fuentes de variabilidad en la prestación de cuidados y el centro de los esfuerzos dirigidos a mejorar la efectividad. Pese a las críticas y limitaciones que la evidencia acusa, no deja de ser una respuesta válida al aumento de la complejidad de las organizaciones sanitarias y de la necesidad de mejorar los resultados de ...
Tópico(s): Healthcare Quality and Management
2003 - Elsevier BV | Enfermería Clínica
José Miguel Morales‐Asencio, Elena Gonzalo-Jiménez, F.J. Martín-Santos, Juan Carlos Morilla Herrera, M Celdráan-Mañas, Almudena Millán Carrasco, JJ García-Arrabal, Isabel Toral-López,
Demand for home care services has increased considerably, along with the growing complexity of cases and variability among resources and providers. Designing services that guarantee co-ordination and integration for providers and levels of care is of paramount importance. The aim of this study is to determine the effectiveness of a new case-management based, home care delivery model which has been implemented in Andalusia (Spain). Quasi-experimental, controlled, non-randomised, multi-centre study ...
Tópico(s): Chronic Disease Management Strategies
2008 - BioMed Central | BMC Health Services Research
José Miguel Morales‐Asencio, Elena Gonzalo Jiménez, Francisco Javier Martín Santos, Juan Carlos Morilla Herrera,
La evaluación de intervenciones en Salud Pública constituye un pilar imprescindible en el desarrollo de políticas de salud, aunque no está exenta de controversias. Su desarrollo requiere la utilización de resultados de investigación, aunque hay grandes escollos derivados de un tradicional enfoque evaluativo basado en el ensayo clínico como patrón de oro, consolidado con el auge de la Medicina Basada en la Evidencia. En Salud Pública no siempre se pueden llevar a cabo diseños clásicos aleatorizados ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2008 - Ministry of Health of Spain | Revista Española de Salud Pública
Mario Fernández‐Ruiz, Juan‐Manuel Guerra‐Vales, Ana-Belén Enguita-Valls, Juan Vila-Santos, Francisco-Javier García-Borda, Carlos Morales-Gutiérrez,
Hydatid disease (HD) is a zoonotic infection caused by the larval stage of the genus Echinococcus (E. granulosus or less frequently, E. multilocularis) with a worldwide distribution, although it remains a considerable public health problem in several Mediterranean countries due to its endemic distribution, including Spain [ 1 Örmeci N. Soykan I. Palabiyikoğlu M. Idilman R. Erdem H. Bektaş A. et al. A new therapeutic approach for treatment of hydatid cysts of the spleen. Dig Dis Sci. 2002; 47: 2037-2044 ...
Tópico(s): Amoebic Infections and Treatments
2008 - Elsevier BV | European Journal of Internal Medicine
Alicia Hidrón, Nicholas Vogenthaler, José Ignacio Santos-Preciado, Alfonso J. Rodríguez‐Morales, Carlos Franco‐Paredes, Anis Rassi,
SUMMARY Parasitic infections previously seen only in developing tropical settings can be currently diagnosed worldwide due to travel and population migration. Some parasites may directly or indirectly affect various anatomical structures of the heart, with infections manifested as myocarditis, pericarditis, pancarditis, or pulmonary hypertension. Thus, it has become quite relevant for clinicians in developed settings to consider parasitic infections in the differential diagnosis of myocardial and ...
Tópico(s): Parasites and Host Interactions
2010 - American Society for Microbiology | Clinical Microbiology Reviews
Daniela Millán, Mabel Rojas, José G. Santos, Javiera Morales, Maurício Isaacs, Carlos Díaz, Paulina Pávez,
An electrochemical technique was used to investigate pKa values of some substituted secondary alicyclic (SA) amines, pyridines (py), anilines (AN), and triethylamine (Et3N) in different ionic liquids. The method involves cyclic voltammetry at a platinized Pt electrode. The experimental data were correlated with pKa values reported previously in aqueous solution, and Hammett parameters were correlated with pKa values in ionic liquids to determine ρ values in these media.
Tópico(s): Chemical and Physical Properties in Aqueous Solutions
2014 - American Chemical Society | The Journal of Physical Chemistry B
José Miguel Morales‐Asencio, Juan Carlos Morilla Herrera, F.J. Martín-Santos, Elena Gonzalo-Jiménez, Magdalena Cuevas‐Fernández‐Gallego, C. Bonill de las Nieves, A. Tobías-Manzano, A. Rivas-Campos,
Tópico(s): Geriatric Care and Nursing Homes
2008 - Elsevier BV | International Journal of Nursing Studies
Verónica Cabanas‐Sánchez, Miguel Angelo dos Santos Duarte, Carl J. Lavie, Carlos Celis‐Morales, Fernando Rodríguez‐Artalejo, David Martínez‐Gómez,
To assess the association of physical activity (PA) with cause-specific cardiovascular disease (CVD) mortality among people with preexisting CVD and to analyze the relationship of PA with CVD-related mortality in people without CVD as well as the association of PA with nonspecific CVD mortality in both populations.
Tópico(s): Physical Activity and Health
2023 - Elsevier BV | Mayo Clinic Proceedings
Juan Eugenio Hernández-Ávila, Mario H. Rodrı́guez, Norma E Rodríguez, René Santos-Luna, Evangelina Morales, Carlos Cruz, Jaime Sepúlveda-Amor,
Objetivo. Determinar la cobertura geográfica del Sistema Mexicano de Salud y analizar la utilización en 1998 de los hospitales de la Secretaría de Salud (SSA). Material y métodos. Se desarrolló un Sistema de Información Geográfica (SIG) con información sociodemográfica por localidad y ubicación espacial de unidades de atención de todo el sector salud, así como el registro de egresos por hospital de la SSA. Se determinó la utilización en 217 hospitales generales de la SSA mediante un modelo de estimación ...
Tópico(s): Spatial and Panel Data Analysis
2002 - Instituto Nacional de Salud Pública | Salud Pública de México
Sofía T. Menéndez, Verónica Rey, Lucia Martinez‐Cruzado, Marı́a Victoria González, Álvaro Morales‐Molina, Laura Santos, Verónica Blanco, Carlos Álvarez-Fernández, Óscar Estupiñán, Eva Allonca, Juan P. Rodrigo, Javier García‐Castro, Juana M. García‐Pedrero, René Rodrı́guez,
Background: Stemness in sarcomas is coordinated by the expression of pluripotency factors, like SOX2, in cancer stem cell (CSC) subpopulations. The role of SOX2 in tumor initiation and progression has been well characterized in osteosarcoma. However, the pro-tumorigenic features of SOX2 have been scarcely investigated in other sarcoma subtypes.Methods: shRNA and cDNA lentiviral constructions were used to deplete and overexpress SOX2 in a model of undifferentiated pleomorphic sarcoma (UPS). In addition, ...
Tópico(s): Cancer Cells and Metastasis
2020 - RELX Group (Netherlands) | SSRN Electronic Journal
José M. Castellano, Juan Verdejo, Salvador Ocampo, Marco Martínez Ríos, Enrique Gómez-Álvarez, Gabriela Borrayo, Emilio Muñoz Ruiz, Borja Ibáñez, Valentı́n Fuster, Misael Arroyo, Maria Teresa Colosia, Juan E. Becerril, Roberto Vázquez, Elías Rodríguez Rodríguez, Alejandro Domínguez-Rodríguez, Rafael Márquez, Enrique Gómez‐Figueroa, Juan Marcos González, Jose L. Ubiarco, Jose Fernando Rincón Barrera, Bertha Vitela, Laura A. Aranda, Victor Waldez Hernandez Peña, Miguel Ángel López Guerrero, Susana Ibarra, Maria I. Córdoba, Gloria Ledesma, Gustavo A. Alarcón, Jose A. Campos, José Luis Díez Gil, Rafael Elias, Víctor H. Báez, Mariano D. Cervantes, Raúl Apresa, Javier Casian, Rafael Serrano del Rosal, David A. Delgado, Joel E. Padrón, Víctor Manuel Vargas Hernández, Maria Antonia Rodriguez, Enrique González, Alejandro García, Francisco Javier González, Miguel A. González, Nadia Álvarez, Jorge Rodríguez, Francisco Martínez‐Martínez, Jose A. Gaxiola, Luis García, Luís Gonzaga, Mirtha Valenzuela, Ezequiel García, Manuel Anguita Sánchez, Manuel González Oropeza, Simón Areola, Guillermo A. Rodríguez, Maria R. Zarate, Maria R. Jaramillo, A. Molina, Félix González, Marisela C. Parra, Rosalba Lara, Delia Ruiz, Alejandro Chávez, Héctor V. Ballardo, Ezequiel Gomez, Antonio Corona, Mario L. Rodriguez, Ramón Flores, José Alberto Castro, Reynaldo J. Jiménez, Jesús M. Acosta, A. Lucía Morales, Enrique A. Velázquez, Gerardo Santana, Juan J. Atilano, María Jiménez, Fernando Rodríguez González, Jose J. Santos, Maria A. Asmida, José Carlos Flores, Raúl Segura, Isilio N. Morales, Javier Solis Estrada, Jorge L. Narváez, Silvia Rivera, Jorge L. Flores, Norma E. Cano, Miguel Ángel López Guerrero, Armando Moreno, Armando G. de la Cruz, Noé D. Monroy, Omar John B. Mejia, Joaquín I. Moreno, Martin Limas, J. Maldonado, Vania Quisbert, Claudia C. Rojas, Mario Flores, Sonia Medina Salgado, Ana K. Villanueva, U Yajaira Romero, Alejandro Daniel Pedraza Tirado, Maria C. Guadalupe, J Villalpando, Alejandro Cortes, Eliceo Gracia, Karla G. Wong, Víctor M. Salas, Jose L. Escobar, Pedro Hernández, Nancy Bello, Rubén O. Yza, Octavio Beltrán, Miguel A. Águila, Francisco Vera‐Sempere, P. A. Rueda Mejia, Juan M. Arellano, Enrique Morlet, Luis E. López, Marco Antonio Martínez‐Ríos, Federico Jimenez‐Ruiz, Yolanda P. Rodriguez, Javier Freire, Alejandro Rivas, Beatriz Mendoza, Sergio Téllez, José Antonio Magaña, Juan A. Quintana, Lázaro Aguilar, Jose Sacen, Edith MC. Vallarta, Fernando Flores García, María Luisa Pimentel Ramírez, Maria T. Olac, German R. Bautista, Juan F. Martı́n, Marcelo Jiménez, Jorge Martínez Cedillo, Eddie A. Favela, Jose Pegueros, José Juan Gómez Becerra, Raul Silva, Armando Zepeda, Jorge Ezequiel Hernández Hernández, Miguel Marvaes, Hilario Flores Aguilar, Ana L. Lerma, Luis Matías Zabala Fuentes,
The cardiovascular disease pandemic has promoted the cardiovascular polypill as one of the most scalable public health strategies to improve cardiovascular risk by increasing accessibility and adherence to treatments. Data from randomized clinical trials has shown that the polypill strategy significantly improves adherence as well as risk factor control (cholesterol and blood pressure), however, to date, no information from phase IV registries has been available. We conducted a multicentre, observational ...
Tópico(s): Pharmaceutical Practices and Patient Outcomes
2019 - Elsevier BV | Archives of Medical Research
Dimaris Acosta-Mercado, N. Cancel-Morales, J. Danilo Chinea, Carlos J. Santos-Flores, I. Sastre de Jesus,
Tópico(s): Bryophyte Studies and Records
2012 - Springer Science+Business Media | Microbial Ecology
Alejandro Santos‐Lozano, Alicia Morales-Gónzalez, Fabián Sanchís-Gomar, Carlos Cristi‐Montero, Carmen Fiuza‐Luces, Helios Pareja‐Galeano, Joaquín Martínez‐López, Nuria Garatachea, Alejandro Lucía,
Waldenström macroglobulinemia (WM) is a malignant lymphoproliferative disorder characterized by the presence of a high level of serum monoclonal IgM and a lymphoplasmacytic infiltrate in the bone marrow. This meta-analysis sought to assess the effectiveness of the different treatments for WM tested in published trials using the response rate (RR) as the main outcome measure. Forty-six articles (1409 patients) identified were entered in a variable effects model meta-analysis of proportions (rates and ...
Tópico(s): Viral-associated cancers and disorders
2016 - Elsevier BV | Critical Reviews in Oncology/Hematology
Produção Nacional
Revisado por pares
Johnatas D. Silva, Lígia Lins de Castro, Cássia L. Braga, Gisele P. Oliveira, Stefano Trivelin, Carlos M. Barbosa-Junior, Marcelo M. Morales, Claúdia C. dos Santos, Daniel J. Weiss, Miquéias Lopes‐Pacheco, Fernanda F. Cruz, Patrícia R. M. Rocco,
Although mesenchymal stromal cells (MSCs) have demonstrated beneficial effects on experimental acute respiratory distress syndrome (ARDS), preconditioning may be required to potentiate their therapeutic effects. Additionally, administration of cell-free products, such as extracellular vesicles (EVs) obtained from MSC-conditioned media, might be as effective as MSCs. In this study, we comparatively evaluated the effects of MSCs, preconditioned or not with serum collected from mice with pulmonary or ...
Tópico(s): Mesenchymal stem cell research
2019 - Hindawi Publishing Corporation | Stem Cells International
Produção Nacional
Revisado por pares
Leonardo Y. Tanaka, Thaı́s L. S. Araujo, Andrés Rodríguez-Morales, Mariana Sacrini Ayres Ferraz, Vitor B. Pelegati, Mauro César Cafundó Morais, Aline Mara dos Santos, Carlos L. César, Alexandre F. Ramos, Adriano M. Alencar, Francisco Rafael Martins Laurindo,
Although redox processes closely interplay with mechanoresponses to control vascular remodeling, redox pathways coupling mechanostimulation to cellular cytoskeletal organization remain unclear. The peri/epicellular pool of protein disulfide isomerase-A1 (pecPDIA1) supports postinjury vessel remodeling. Using distinct models, we investigated whether pecPDIA1 could work as a redox-dependent organizer of cytoskeletal mechanoresponses. In vascular smooth muscle cells (VSMCs), pecPDIA1 immunoneutralization ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2018 - American Physical Society | AJP Heart and Circulatory Physiology
Carlos Franco‐Paredes, Nadine Rouphael, José Carlos Méndez, Erik Folch, Alfonso J. Rodríguez‐Morales, José Ignacio Santos, J. Willis Hurst,
Abstract This is part two of a three‐part series discussing parasites of the heart. In this section, we present an overview on parasitic diseases predominantly involving the myocardium. Copyright © 2007 Wiley Periodicals, Inc.
Tópico(s): Vector-borne infectious diseases
2007 - Wiley | Clinical Cardiology
Carlos Franco‐Paredes, Nadine Rouphael, José Carlos Méndez, Erik Folch, Alfonso J. Rodríguez‐Morales, José Ignacio Santos, J. Willis Hurst,
Parasitic infections produce a wide spectrum of cardiac manifestations. They may involve various anatomic structures of the heart and are manifested clinically as myocarditis, cardiomyopathies, pericarditis, or pulmonary hypertension in many resource-constrained settings. However, many parasitic infections involving the heart may also be currently diagnosed in developed countries due to growing worldwide travel, blood transfusions, and increasing numbers of immunosuppression states such as organ ...
Tópico(s): Parasitic Diseases Research and Treatment
2007 - Wiley | Clinical Cardiology
Carlos Franco‐Paredes, Nadine Rouphael, José Carlos Méndez, Erik Folch, Alfonso J. Rodríguez‐Morales, José Ignacio Santos, J. Willis Hurst,
Abstract This is part three of a three‐part series discussing parasites of the heart. In this section, we present an overview on parasitic diseases involving predominantly the pericardium and other miscellaneous cardiopulmonary manifestations such as some pulmonary hypertension syndromes and endomyocardial fibrosis. Copyright © 2007 Wiley Periodicals, Inc.
Tópico(s): Parasites and Host Interactions
2007 - Wiley | Clinical Cardiology
Pablo Santos Gorjón, Pedro Blanco Pérez, Ana Cristina Morales Martín, Juan Carlos del Pozo de Dios, José Santiago Estévez-Alonso, María Isabel Calle Cabanillas,
Las infecciones cervicales profundas (ICP) son afecciones potencialmente letales y susceptibles de complicaciones graves. En este estudio se constata el aumento de la incidencia y se trata de buscar las causas. Más del 30% son idiopáticas, pero suelen relacionarse con infecciones dentarias y orofaríngeas. Se presentan 286 ICP consecutivas en un estudio retrospectivo de los últimos 11 años en nuestro centro y se analizan antecedentes y enfermedades concomitantes y aspectos diagnósticos y terapéuticos ...
Tópico(s): Streptococcal Infections and Treatments
2011 - Elsevier BV | Acta Otorrinolaringológica Española
Pablo Santos Gorjón, Pedro Blanco Pérez, Ana Cristina Morales Martín, Juan Carlos del Pozo de Dios, José Santiago Estévez-Alonso, María Isabel Calle Cabanillas,
Deep neck infections (DNI) are potentially lethal processes and are susceptible to severe complications. This study shows an increment of the incidence and investigated the cause. More than 30% of cases are idiopathic, but they are commonly related to a dental or oropharyngeal infection. We present 286 consecutive cases in a retrospective 11-year study. We analysed the clinical picture, antecedents and concurrent diseases, and diagnostic and therapeutic approaches that could be related to developing ...
Tópico(s): Infectious Diseases and Tuberculosis
2012 - Elsevier BV | Acta Otorrinolaringologica (English Edition)