William Leith, Jeremy Andrews, Anatol Lioven, Juan Carlos Gumucio, Graham Rock, Rebecca Johnson, Nicholas Wood, Political Correspondent, Anatol Lieven, Zahid Hussain, Vijitha Yapa, Simon Barnes, S. A. Tooth, Andrew Longmore, Neil Bennett, Partrick Hall-Smith, Ivo Tennant, Ian Smith and Ronald Faux, Douglas Broom, Education Reporter, Ian Murray, Michael Binyon, Jeremy Kingston, James Bone, John Bellak, George Sivell, Mandarin (Michael Phillips), Carol Leonard, P. M. Lewis, Richard Streeton, Kevin Eason, Motoring Correspondent, P. C. E. Creasy General Secretary, Michael Young, Colin Narbrough, Kevin Eason, Tim Jones and Philip Webster, Martin Fletcher, Henry Gee, Sam Kiley Higher Education Reporter, Nicholas Wood Political Correspondent, Cruise O'Brinen, Raymond Keene Chess Correspondent, Thomson Prentice Science Correspondent, Peter Waymark, David Butler, Jenny MacArthur, Michael Clark, Martin Fletcher, Political Reporter, D. M. MacDowell, Tony Winlaw, Barry Fantoni, Charles Bremner, Jamie Crookenden, Elizabeth Stanley, Mark Souster and Andrew Morgan, John Hennessy, Michael Howard, Peter Galliner Director, Jack Andrews, H. V. Hodson, Dick Hinder, Peter Freedman, John Woodcock, Rex Bellamy Tennis Correspondent, Edward Gorman, Irish Affairs Correspondent, Sydney Friskin, John Goodbady, Dennis Signy, Mary Lutyens, I. R. Montgomery, Patricia Davies Pals, Geoffrey Wheeler, Wolfgang Münchau, Robin Oakley, Political Editor, Catherine Sampson, Peter Davalle, Alan Lee, Cricket Correspondent, Emma Wilkins, Barbara Amiel, Raymond Keene, Chess Correspondent, Paul Griffiths, Claire Haggard, Jill Sherman, Craig Seton, J. C. Overton, Martin Searby, Irving Wardle, Martin Fletcher and Nick Nuttall, Michael Hornsby, Agriculture Correspondent, David Hands Rugby Correspondent, David Brewerton, David Young, Philip Webster Chief Political Correspondent, Christopher Walker, Jill Sherman Social Services Correspondent, Tony Smythe, Gitta Sereny, John Wilcockson, Mel Webb, Ken Dodd, Matthew Parris, Sarah Jane Checkland Art Market Correspondent, Sallie Ecroyd, Michael Austin, Wolfgang Munchan, Jack Balley, Martin Waller, Alan Coren, John Lewis and Richard Ford, Pat Butcher Athletics Correspondent, Peter Kenny, Derek Harris Industrial Editor, Michael Evans, Harvey Elliott Air Correspondent, Colin Campbell, Judy Lowe, Cliff Feltham and George Sivell, Vivien Goldsmith, Family Money Editor, Peter Evans, Home Affairs Correspondent, Robert Kilroy-Silk, A. Graham Hellier, John Watson, John Goodbody and David Sapsted,
... Mandarin: Haydock Park Selections The Times Racing Service ROA Critical of missed opportunity in levy negotiations Hoist ...
1989 - Gale Group | TDA
... doi.org/10.1002/9780470015902.a0027214Jonatan J. Hernández Roa, Carlos R. Virella, Matías J. Cafaro First survey of ...
Tópico(s): Forest Ecology and Biodiversity Studies
1920 - University of Chicago Press | Botanical Gazette
Cristian A. Álvarez Rojas, Dennis Ebi, Rodolfo Paredes, Gerardo Acosta‐Jamett, Urriola Nicole, Juan Carlos Roa, Carlos Manterola, Sandra Cortés, Thomas Romig, Jean‐Pierre Y. Scheerlinck, Marshall W. Lightowlers,
Echinococcus granulosus sensu stricto is the major cause of cystic echinococcosis in most human and animal cases in the world and the most widespread species within the E. granulosus sensu lato complex. E. granulosus s.s. remains endemic in South America together with other species of the Echinococcus genus, especially in some areas in Argentina, Brazil, Chile and Peru. Except for a single human case caused by E. canadensis (G6) described in the literature, only E. granulosus s.s. has been found ...
Tópico(s): Amoebic Infections and Treatments
2016 - Elsevier BV | Parasitology International
Manuel De Jesus Encarnación Ramírez, G. E. Chmutin, Renat Nurmukhametov, Gervith Reyes Soto, Siddarth Kannan, Gennadi Piavchenko, В.Н. Николенко, Ibrahim E. Efe, Alberto Ramírez Romero, Jeff Ntalaja Mukengeshay, Keith Simfukwe, Tshiunza Mpoyi Chérubin, Federico Nicolosi, Salman Sharif, Juan Carlos Roa, Nicola Montemurro,
Introduction: The integration of augmented reality (AR) in spine surgery marks a significant advancement, enhancing surgical precision and patient outcomes. AR provides immersive, three-dimensional visualizations of anatomical structures, facilitating meticulous planning and execution of spine surgeries. This technology not only improves spatial understanding and real-time navigation during procedures but also aims to reduce surgical invasiveness and operative times. Despite its potential, challenges ...
Tópico(s): Anatomy and Medical Technology
2024 - Multidisciplinary Digital Publishing Institute | Brain Sciences
Iván Roa, Gilda Ibacache, Juan Carlos Roa, Juan Carlos Araya, Xabier de Aretxabala, Sergio Muñoz,
Abstract Background Gallstones are considered the most important risk factor for gallbladder cancer. Aim To identify differences in the number, weight, volume, and density of gallstones associated with chronic cholecystitis (CC), gallbladder dysplasia (GD), and gallbladder cancer (GBC). Methods A total of 125 cases were selected, of which 93 had gallstones associated with GBC and 31 had gallstones associated with GD. The controls were those with CC, matched by sex and age. The number, weight, volume, ...
Tópico(s): Biliary and Gastrointestinal Fistulas
2006 - Wiley | Journal of Surgical Oncology
Orhun Çığ Taşkın, Gizem Akkaş, Bahar Memiş, İpek Erbarut Seven, Olca Baştürk, Kee‐Taek Jang, Juan Carlos Roa, Juan Carlos Araya, Enrique Bellolio, H. Losada, Juan M. Sarmiento, Serdar Balcı, Burçin Pehlivanoğlu, Michelle D. Reid, Jill Koshiol, Volkan Adsay,
Sarcomatoid carcinomas recently came into the spotlight through genetic profiling studies and also as a distinct model of epithelial–mesenchymal transition. The literature on sarcomatoid carcinomas of gallbladder is limited. In this study, 656 gallbladder carcinomas (GBC) were reviewed. Eleven (1.7%) with a sarcomatoid component were identified and analyzed in comparison with ordinary GBC (O-GBC). Patients included 9 females and 2 males (F/M = 4.5 vs. 3.9) with a mean age-at-diagnosis of 71 (vs. 64). The ...
Tópico(s): Cancer Diagnosis and Treatment
2019 - Springer Science+Business Media | Virchows Archiv
Orhun Çığ Taşkın, Enrique Bellolio, Nevra Dursun, İpek Erbarut Seven, Juan Carlos Roa, Juan Carlos Araya, Miguel Villaseca, Óscar Tapia, Courtney L. Vance, Burcu Saka, Serdar Balcı, Pelin Bağcı, H. Losada, Juan M. Sarmiento, Bahar Memiş, Burçin Pehlivanoğlu, Olca Baştürk, Michelle D. Reid, Jill Koshiol, Jeanette D. Cheng, Yersu Kapran, Volkan Adsay,
There is no systematic histopathologic analysis of non-neoplastic polyps in the gallbladder. In this study, in addition to a computer search for cases designated as “polyp,” a systematic review of 2533 consecutive routinely sampled archival and 203 totally submitted prospective cholecystectomies were analyzed for >2 mm polyps (cut-off was based on radiologic sensitivity). A total of 447 non-neoplastic polyps were identified. The frequency was 3% in archival cases and 5% in totally submitted cases. ...
Tópico(s): Genetic factors in colorectal cancer
2019 - Lippincott Williams & Wilkins | The American Journal of Surgical Pathology
Ismael Riquelme, Carmen Ili, Juan Carlos Roa, Priscilla Brebi,
... Riquelme 1,2 , Carmen Ili 1,2 , Juan Carlos Roa 3 and Priscilla Brebi 1,2 1 Molecular ...
Tópico(s): Circular RNAs in diseases
2016 - Impact Journals LLC | Oncotarget
Xinyan Wu, Muhammad Saddiq Zahari, Binyun Ma, Ren Liu, Santosh Renuse, Nandini A. Sahasrabuddhe, Lily Chen, Raghothama Chaerkady, Min‐Sik Kim, Jun Zhong, Christine Jelinek, Mustafa A. Barbhuiya, Pamela Leal, Yi Yang, Manoj Kumar Kashyap, Arivusudar Marimuthu, Ling Min, Mary Jo Fackler, Vanessa F. Merino, Zhen Zhang, Cynthia A. Zahnow, Edward Gabrielson, Vered Stearns, Juan Carlos Roa, Saraswati Sukumar, Parkash S. Gill, Akhilesh Pandey,
... Edward Gabrielson 3, 4 , Vered Stearns 3 , Juan Carlos Roa 8 , Saraswati Sukumar 3 , Parkash S. Gill 6 , ...
Tópico(s): Microtubule and mitosis dynamics
2015 - Impact Journals LLC | Oncotarget
Xabier de Aretxabala, Iván Roa, Juan Carlos Araya, L. Burgos, Paloma Largo Flores, Ignacio I. Wistuba, Miguel Villaseca, Fiorella Sotomayor, Juan Carlos Roa,
Journal Article Gallbladder cancer in patients less than 40 years old Get access X de Aretxabala, X de Aretxabala Department of Surgery, Universidad de la Frontera, Temuco, Chile Correspondence to: Dr X. de Aretxabala, Faculty of Medicine, Universidad de la Frontera, PO Box 54-D, Temuco, Chile Search for other works by this author on: Oxford Academic Google Scholar I Roa, I Roa Department of Pathology, Universidad de la Frontera, Temuco, Chile Search for other works by this author on: Oxford Academic ...
Tópico(s): Viral-associated cancers and disorders
1994 - Oxford University Press | British journal of surgery
Isela Esther Juárez‐Rojop, Carlos Alfonso Tovilla‐Zárate, Dora E. Aguilar-Domínguez, Luis F. Roa, Carlos E. Lobato‐García, Jorge L. Blé‐Castillo, María Leonor López‐Meraz, Juan C. Díaz-Zagoya, Deysi Y. Bermudez‐Ocaña,
The extraction of plant constituents is essential to isolate biologically active compounds, aimed to understand their role on the treatment of diabetes.This study was designed to explore the preliminary phytochemical and physicochemical analysis of Carica papaya L., Caricaceae, leaf, and further evaluation of its hypoglycemic effect on diabetic rats. C. papaya leaves were extracted using chloroform, n-hexane or ethanol. For each extract a phytochemical screening was performed. The tests were conducted ...
Tópico(s): Cassava research and cyanide
2014 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Juan Carlos Roa, Óscar Tapia, Carlos Manterola, Miguel Villaseca, Pablo Guzmán, Juan Carlos Araya, Pelin Bağcı, Burcu Saka, Volkan Adsay,
Tópico(s): Gallbladder and Bile Duct Disorders
2013 - Springer Science+Business Media | Virchows Archiv
Abraham Gómez‐Rivera, Hidemí Aguilar-Mariscal, Nancy Romero‐Ceronio, Luis F. Roa, Carlos E. Lobato‐García,
The aim of this study was to synthesize three nitro substituted chalcones and to evaluate their anti-inflammatory activity in the model of carrageenan induced edema in rats. The nitro chalcone were prepared by aldol condensation using of mechanical agitation and environmentally friendly solvents with 72-73% yields in approximately 2h. The three structures were evaluated on biological activity at dose of 200mg/kg and they showed anti-inflammatory protective effect by both oral and intraperitoneal ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2013 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Paula López-Roa, Carlos Sánchez Carrillo, Mercedes Marín, Francisco J. Romero–Salguero, Emilia Cercenado, Emilio Bouza,
Phenotypic tests do not always unequivocally identify some species of viridans group streptococci (VGS). sodA sequence analysis is the most accurate method for identification, although it requires specialized personnel and has not been applied systematically in clinical microbiology laboratory routines. Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is emerging as a rapid alternative for bacterial identification. This study assesses the ability of MALDI-TOF and the API 20 Strep ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2012 - Elsevier BV | Clinical Microbiology and Infection
Magdalena E. Cuevas, Henny Haensgen, Fernando J. Sepúlveda, Gabriela Zegers, Jorge Roa, Carlos Opazo, Luis G. Aguayo,
It is believed that amyloid-β peptide (Aβ), in its aggregated-oligomeric state, constitutes one of the neurotoxic factors involved in the pathogenesis of Alzheimer's disease. With the objective of studying a potential role of the peptide on synaptic transmission, we studied the effect of soluble Aβ(1-40) on synaptic transmission in rat hippocampal neurons. Neurons incubated with 500 nM of Aβ(1-40) peptide for 3 days presented higher levels of intracellular calcium transients, as evaluated by fluorimetric ...
Tópico(s): Computational Drug Discovery Methods
2011 - IOS Press | Journal of Alzheimer s Disease
J. Minguela, Daniel Müller, Frank Mücklich, L. Llanes, Maria‐Pau Ginebra, J.J. Roa, Carlos Mas‐Moruno,
A dual approach employing peptidic biofunctionalization and laser micro-patterns on dental zirconia was explored, with the aim of providing a flexible tool to improve tissue integration of restorations. Direct laser interference patterning with a femtosecond Ti:Sapphire laser was employed, and two periodic grooved patterns were produced with a periodicity of 3 and 10 μm. A platform containing the cell-adhesive RGD and the osteogenic DWIVA peptides was used to functionalize the grooved surfaces. ...
Tópico(s): Laser Applications in Dentistry and Medicine
2021 - Elsevier BV | Materials Science and Engineering C
Fernando de Andrés, Catalina Altamirano-Tinoco, Ronald Ramírez‐Roa, Carlos F Montes-Mondragón, Pedro Dorado, Eva Peñas‐Lledó, Adrián LLerena,
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2020 - Springer Nature | The Pharmacogenomics Journal
Produção Nacional
Revisado por pares
Molly McNett, Ericka L. Fink, Michelle E. Schober, Shraddha Mainali, Raimund Helbok, Courtney Robertson, Jorge Mejía-Mantilla, Pedro Kurtz, Cássia Righy, Juan D. Roa, Carlos Villamizar-Rosales, Valeria Altamirano, Jennifer Frontera, Nelson Maldonado, David Menon, José I. Suárez, Sherry Chou,
Tópico(s): Intensive Care Unit Cognitive Disorders
2020 - Springer Science+Business Media | Neurocritical Care
Mario Zanaty, Susanna Howard, Jorge A. Roa, Carlos M. Alvarez, David Kung, David J. McCarthy, Edgar A. Samaniego, Daichi Nakagawa, Robert M. Starke, Kaustubh Limaye, Sami Al Kasab, Nohra Chalouhi, Pascal Jabbour, James C. Torner, Daniel Tranel, David Hasan,
Revascularization of a symptomatic, medically refractory, cervical chronically occluded internal carotid artery (COICA) using endovascular techniques (ETs) has surfaced as a viable alternative to extracranial-intracranial bypass. The authors aimed to assess the safety, success, and neurocognitive outcomes of recanalization of COICA using ETs or hybrid treatment (ET plus carotid endarterectomy) and to identify candidate radiological markers that could predict success.
Tópico(s): Acute Ischemic Stroke Management
2019 - American Association of Neurological Surgeons | Journal of neurosurgery
Eloy F. Robles, Maria Mena‐Varas, Laura Barrio, Sara V. Merino-Cortés, Péter Balogh, Ming‐Qing Du, Takashi Akasaka, Anton Parker, Sergio Roa, Carlos Panizo, Idoia Martín‐Guerrero, Reiner Siebert, Víctor Segura, Xabier Agirre, Laura Macri-Pellizeri, Beatriz Aldaz, Amaia Vilas‐Zornoza, Shaowei Zhang, Sarah Moody, Marı́a José Calasanz, Thomas Tousseyn, Cyril Broccardo, Pierre Brousset, Elena Campos-Sánchez, César Cobaleda, Isidro Sánchez‐García, José L. Fernández-Luna, Ricardo Garcı́a-Muñoz, Esther Peña, Beatríz Bellosillo, Antonio Salar, Maria João Baptista, Jesús María Hernández‐Rivas, Marcos González, María José Terol, Joan Climent, Antonio Ferŕandez, Xavier Sagaert, Ari Melnick, Felipe Prósper, David Oscier, Yolanda R. Carrasco, Martin J.S. Dyer, José A. Martínez-Climent,
Abstract NKX2 homeobox family proteins have a role in cancer development. Here we show that NKX2 - 3 is overexpressed in tumour cells from a subset of patients with marginal-zone lymphomas, but not with other B-cell malignancies. While Nkx2-3 -deficient mice exhibit the absence of marginal-zone B cells, transgenic mice with expression of NKX2-3 in B cells show marginal-zone expansion that leads to the development of tumours, faithfully recapitulating the principal clinical and biological features of ...
Tópico(s): Immunotherapy and Immune Responses
2016 - Nature Portfolio | Nature Communications
Jose Mateus, Paola Lasso, Paula Pavía, Fernando Rosas, Nubia Roa, Carlos A. Valencia‐Hernández, John Mario González, Concepción J. Puerta, Adriana Cuéllar,
Background CD8+ T cells have been shown to play a crucial role in Trypanosoma cruzi infection. Memory CD8+ T cells can be categorised based on their distinct differentiation stages and functional activities as follows: stem cell memory (TSCM), central memory (TCM), transitional memory (TTM), effector memory (TEM) and terminal effector (TTE) cells. Currently, the immune mechanisms that control T. cruzi in the chronic phase of the infection are unknown. Methodology/Principal Findings To characterise the ...
Tópico(s): Immune Cell Function and Interaction
2015 - Public Library of Science | PLoS neglected tropical diseases
Roberto García‐Roa, Carlos Cabido, Pílar López, José Martı́n,
Chemical signals play an important role in intraspecific communication and social organization of many animals, but they also may be useful in interspecific recognition. In lizards, chemical signals are often contained in femoral gland secretions, of which composition may vary between species and populations. This may be especially important in recognition and reproductive isolation between closely related species. We analyzed by gas chromatography–mass spectrometry (GC–MS) the lipophilic fraction ...
Tópico(s): Insect and Arachnid Ecology and Behavior
2015 - Elsevier BV | Biochemical Systematics and Ecology
Jorge Parodí, Fernando J. Sepúlveda, Jorge Roa, Carlos Opazo, Nibaldo C. Inestrosa, Luis G. Aguayo,
Alzheimer disease is a progressive neurodegenerative brain disorder that leads to major debilitating cognitive deficits. It is believed that the alterations capable of causing brain circuitry dysfunctions have a slow onset and that the full blown disease may take several years to develop. Therefore, it is important to understand the early, asymptomatic, and possible reversible states of the disease with the aim of proposing preventive and disease-modifying therapeutic strategies. It is largely unknown ...
Tópico(s): Lipid Membrane Structure and Behavior
2009 - Elsevier BV | Journal of Biological Chemistry
Jonatan J. Hernández Roa, Carlos R. Virella, Matías J. Cafaro,
This is the first survey of trichomycetes for Vieques, Puerto Rico. Several types of arthropods, including millipedes, crabs, mosquitoes, bloodworms, amphipods and isopods, were collected from marine, freshwater and terrestrial habitats and their guts examined for the presence of trichomycetes. A new species of Enterobryus, which was found attached to the gut of the millipede Anadenobolus arboreus (Diplopoda), is described as Enterobryus viequensis sp. nov. We report the presence of Smittium culisetae ...
Tópico(s): Plant Disease Resistance and Genetics
2009 - Taylor & Francis | Mycologia
Evelyn Zoppi de Roa, Carlos López,
An updated checklist of cladoceran orders Ctenopoda and Anomopoda from inland aquatic habitats in Venezuela is provided, containing a total of 112 species grouped into 39 genera. Recorded cladoceran species of Venezuela represent 30% of the world’s described 370 species of Ctenopoda and Anomopoda. The most representative genera are Alona, Diaphanosoma, Moina, Macrothrix, and Chydorus with 19, 10, 7, 6, and 5 species, respectively. Most records (45%) are Neotropical and about 4% are endemic species. ...
Tópico(s): Marine Biology and Ecology Research
2008 - Q15088586 | Zootaxa
Paolo Moretti, Sarika U. Peters, Daniela del Gaudio, Trilochan Sahoo, Keith Hyland, Teodoro Bottiglieri, Robert J. Hopkin, Elizabeth Peach, Sang Hee Min, David Goldman, Benjamin B. Roa, Carlos A. Bacino, Fernando Scaglia,
We studied seven children with CNS folate deficiency (CFD). All cases exhibited psychomotor retardation, regression, cognitive delay, and dyskinesia; six had seizures; four demonstrated neurological abnormalities in the neonatal period. Two subjects had profound neurological abnormalities that precluded formal behavioral testing. Five subjects received ADOS and ADI-R testing and met diagnostic criteria for autism or autism spectrum disorders. They exhibited difficulties with transitions, insistence ...
Tópico(s): Child Nutrition and Feeding Issues
2007 - Springer Science+Business Media | Journal of Autism and Developmental Disorders
Benjamin B. Roa, CARLO V. SAVINO, C. Sue Richards,
Bloom syndrome is an autosomal recessive disorder characterized clinically by small size, sun-sensitive facial erythema, and immunodeficiency, and cytogenetically by increased chromosome breakage and sister chromatid exchange. Genomic instability renders Bloom syndrome patients at elevated risk for multiple cancers. Bloom syndrome occurs most commonly in the Ashkenazi Jewish population due to an apparent founder effect. The BLM gene on chromosome 15q26.1 was identified to encode a RecQ DNA helicase. ...
Tópico(s): DNA Repair Mechanisms
1999 - Mary Ann Liebert, Inc. | Genetic Testing
Benjamin B. Roa, Carlos A. Garcia, Pentao Liu, James M. Killian, Barbara J. Trask, Ueli Suter, G. Jackson Snipes, Rocio Ortı́z-López, Eric M. Shooter, Pragna I. Patel, James R. Lupski,
Tópico(s): Botulinum Toxin and Related Neurological Disorders
1993 - Nature Portfolio | Nature Genetics
Benjamin B. Roa, Carlos A. Garcia, Ueli Suter, Deanna A. Kulpa, Carol A. Wise, J.J. Mueller, Andrew A. Welcher, G. Jackson Snipes, Eric M. Shooter, Pragna I. Patel, James R. Lupski,
Charcot-Marie-Tooth disease (CMT) is the most common inherited peripheral neuropathy. CMT type 1A is associated with a 1.5-megabase (Mb) DNA duplication in region p11.2-p12 of chromosome 17 in most patients. An increased dosage of a gene within the duplicated segment appears to cause the disease. The PMP22 gene, which encodes a myelin protein, has been mapped within the duplication and proposed as a candidate gene for CMT type 1A.
Tópico(s): Neurological diseases and metabolism
1993 - Massachusetts Medical Society | New England Journal of Medicine
Burcu Saka, Bahar Memiş, İpek Erbarut Seven, Burçin Pehlivanoğlu, Serdar Balcı, Pelin Bağcı, Michelle D. Reid, Nevra Dursun, Oscar Tapia Escalano, Juan Carlos Roa, Juan Carlos Araya, So Yeon Kong, Olca Baştürk, Jill Koshiol, Volkan Adsay,
Context. Follicular cholecystitis (FC) is a poorly characterized entity. Objective. To determine its frequency/clinicopathologic associations. Design. A total of 2550 cholecystectomy specimens were examined. Two hundred three of these were consecutive routine cholecystectomies submitted entirely for microscopic examination to determine the relative frequency of incidental pathologies in gallbladders (GBs). The remainder had representative sampling. Underlying conditions were nonobstructive pathologies ( ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2020 - SAGE Publishing | International Journal of Surgical Pathology