... the east coast of South America from Cape Vela to the Oronoko, from actual observation and the ... Major-General Carmichael to Viscout Castlereagh, dated Saint Carlos, before the city of St. Domingo, 8th July, ...
0000 - Gale Group | Sabin Jan-Jun 2013
Juan Carlos Yébenes, Carol Lorencio, Elisabeth Esteban, L. Espinosa, Josep M. Badía, Capdevila Ja, Berta Cisteró, Shabelly Andrea Tabares Moreno, Esther Calbo, Xavier Jiménez-Fábrega, Montserrat Clèries, María Teresa Faixedas, Ricard Ferrer, Emili Vela, Carlos Bravo, Alejandro Rodríguez, C. Netto, E. Armero, Montserrat Simó-Solsona, Rosalba Lopez, A. Granes, V. Perez-Claveria, Antonio Artigas, J Estany,
La sepsis es una entidad sindrómica de elevada prevalencia y mortalidad. Su manejo está estandarizado y tiene una eficacia dependiente del tiempo. Sin embargo, el manejo de los pacientes con sepsis es complejo. La heterogeneidad de las formas de presentación puede dificultar su detección y manejo, así como las diferencias en formación, competencias o disponibilidad de recursos sanitarios. La Comisión Asesora para la Atención al PAciente con Sepsis (CAAPAS), formada por 7 sociedades científicas, el ...
Tópico(s): Nosocomial Infections in ICU
2019 - Elsevier BV | Medicina Intensiva
... the east coast of South America from Cape Vela to the Oronoko, from actual observation and the ... Major-General Carmichael to Viscout Castlereagh, dated Saint Carlos, before the city of St. Domingo, 8th July, ...
0000 - Gale Group | Sabin Jan-Jun 2013
Pedro García-Martínez, Rafael Ballester‐Arnal, Kavita Gandhi-Morar, Jesús Castro‐Calvo, Vicente Gea-Caballero, Raúl Juárez‐Vela, Carlos Saus‐Ortega, Raimunda Montejano‐Lozoya, Eva María Sosa-Palanca, María José Gómez-Romero, Eladio Collado‐Boira,
Background: Patients with chronic kidney disease undergo various stages of therapeutic adaptation which involve lifestyle modifications, physical changes, and adjustment to renal replacement therapy. This process produces adaptive stress. Objective: To identify how resilience, health- related quality of life, and sociodemographic, clinical, and hemodialysis routine-related variables are related to perceived stress in patients with chronic kidney disease receiving hemodialysis for more than six months. ...
Tópico(s): Resilience and Mental Health
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Paloma Vela, Carlos Sánchez‐Piedra, Carolina Pérez-García, Carmen Castro, Mercedes Freire, Lourdes Mateo, Cèsar Díaz‐Torné, C. Bohórquez Heras, J. M. Blanco-Madrigal, Inmaculada Ros‐Vilamajó, Silvia Solera Gómez, Rocío Caño, Fernando Sánchez‐Alonso, Federico Díaz‐González, Juan J. Gómez‐Reino,
To assess whether age, at the beginning of biologic treatment, is associated with the time a first adverse event (AE) appears in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), or psoriatic arthritis (PsA).All patients in the BIOBADASER registry diagnosed with RA, AS, and PsA, and classified as young (< 25 years old), adult (25-64 years old), elderly (65-75 years old) or very elderly (> 75 years old) at start of biological treatment were included. Factors associated with the appearance ...
Tópico(s): Inflammatory Bowel Disease
2020 - BioMed Central | Arthritis Research & Therapy
Mónica Garcı́a, Marina Virgili, Mónica Alonso, Carles Alegret, Joan Farran, Begoña Fernández, Magda Bordas, Rosalía Pascual, Javier Burgueño, Alba Vidal‐Torres, Antonio R. Fernández de Henestrosa, Eva Ayet, Manuel Merlos, José Miguel Vela, Carlos R. Plata‐Saláman, Carmen Almansa,
The synthesis and pharmacological activity of a new series of 4-alkyl-1-oxa-4,9-diazaspiro[5.5]undecane derivatives as potent dual ligands for the σ1 receptor (σ1R) and the μ-opioid receptor (MOR) are reported. A lead optimization program over the initial 4-aryl analogues provided 4-alkyl derivatives with the desired functionality and good selectivity and ADME profiles. Compound 14u (EST73502) showed MOR agonism and σ1R antagonism and a potent analgesic activity, comparable to the MOR agonist oxycodone ...
Tópico(s): Phenothiazines and Benzothiazines Synthesis and Activities
2020 - American Chemical Society | Journal of Medicinal Chemistry
Produção Nacional
Revisado por pares
Behnood Bikdeli, J.L. Lobo, David Jiménez, Philip Green, Carmen Fernández‐Capitán, A. Bura-Rivière, Remedios Otero, Marco R. DiTullio, Silvia Galindo, Martin Ellis, Sahil A. Parikh, Manuel Monréal, Paolo Prandoni, Benjamin Brenner, Dominique Farge, Raquel Barba, Pierpaolo Di Micco, Laurent Bertoletti, Inna Tzoran, Abílio Reis, Henri Bounameaux, Radován Malý, Peter Verhamme, Marijan Bosevski, Joseph A. Caprini, My Bui, M.D. Adarraga, Miguel Ángel Aibar Arregui, Jesús Aibar, Michael Alfonso, Cristina Amado, C. Monserrat, J.I. Arcelus, Uxua Asín, Pedro María Azcárate-Agüero, Aitor Ballaz, M. Barrón, B. Barrón‐Andrés, J. Bascuñana, Á. Blanco-Molina, A.M. Camón, C. Carrasco, N. Castejón‐Pina, A.J. Cruz, Cristina de Ancos, J. del Toro, Carmen Díaz‐Pedroche, J.A. Díaz‐Peromingo, C. Falgá, A.I. Farfán, M.A. Fidalgo, Carme Font, Llorenç Font, I. Furest, Marian García-Núñez, F. García‐Bragado, Marcial García-Morillo, O. Gavín, Alfredo Gil, Vicente Gómez del Olmo, J. González‐Martínez, E Grau, Ricardo Guijarro, L. Guirado, Juan Mata, Luis Blasco, Clara Iglesias, Luis Jara‐Palomares, M.J. Jaras, Ruth Jiménez Castuera, I. Jou, M.D. Joya, J. Lima, Luciano López‐Jiménez, Patricia López-Miguel, Juan J. López-Núñez, Raquel López-Reyes, J.B. López‐Sáez, M.A. Lorente, A. Lorenzo, Mónica Loring, S. Loscos, M. Lumbierres, P.J. Marchena, C. Martínez‐Baquerizo, Miguel Martín Asenjo, Miguel Martín-Fernández, J.M. Martín‐Guerra, M.V. Morales, J.A. Nieto, Manuel Jesús Núñez, M.C. Olivares, S. Otálora, José María Pedrajas, G. Pellejero, C. Pérez‐Ductor, M.L. Peris, M.L. Pesce, José Antonio Porras, David Riesco, A. Rivas, M.A. Rodríguez‐Dávila, Irene Rodríguez-Galán, A. Rodríguez‐Hernández, V. Rosa, Carmen Ma. Rubio, Pedro Ruiz‐Artacho, Justo Ruiz-Ruiz, Joan Carles Sahuquillo, M.C. Sala‐Sainz, A. Sampériz, J.F. Sánchez‐Muñoz‐Torrero, Teresa Sancho, I.D. Sanoja, S. Soler, María José Monteagudo Soto, J.M. Suriñach, Marı́a Isabel Torres, Javier Trujillo‐Santos, Fernando Uresandi, Esther Usandizaga, R. Valle, J. Vela, Carlos Vilar, A. Villalobos, Fernando Javier Vázquez, Alicia Vilaseca, Christophe Vandenbriele, A. Hij, A. Merah, I. Mahé, Farès Moustafa, Martin Ellis, Cristiano Bortoluzzi, B. Brandolin, Eugenio Bucherini, Maurizio Ciammaichella, Francesco Dentali, Elvira Grandone, Egidio Imbalzano, Gianfranco Lessiani, R. Maida, Daniela Mastroiacovo, Võ Trương Như Ngọc, F. Pace, Roberto Parisi, Raffaele Pesavento, Massimiliano Pinelli, Roberto Quintavalla, Anna Rocci, Roberta Romualdi, Carmine Siniscalchi, P. Sotgiu, Eros Tiraferri, Antonella Tufano, A. Visonà, Beniamino Zalunardo, Andris Skride, Barbara Vītola, Marija Zdraveska, Lucia Mazzolai,
Background Transthoracic echocardiography ( TTE ) is often considered for risk stratification of patients with acute pulmonary embolism ( PE ). We sought to determine the contemporary utilization of early TTE (within 72 hours of PE diagnosis) and explored the association between TTE findings and PE ‐related mortality. Methods and Results Data from the RIETE (Registro Informatizado Enfermedad TromboEmbolica) registry, a multicenter registry of consecutive patients with acute PE , were used (2001–July 2017). We ...
Tópico(s): Acute Myocardial Infarction Research
2018 - Wiley | Journal of the American Heart Association
Alejandra Darling, Cristina Tello, M. J. Martí, Cristina Garrido, Sergio Aguilera, Miguel Tomás Vila, Itziar Gastón, Marcos Madruga, Luis González Gutiérrez, Julio Ramos Lizana, Montserrat Pujol, Tania Gavilán Iglesias, Kylee Tustin, Jean‐Pierre Lin, Giovanna Zorzi, Nardo Nardocci, Loreto Martorell, Gustavo Lorenzo, Fuencisla Gutiérrez, Pedro José González García, Lydia Vela, Carlos Hernández Lahoz, Juan Darío Ortigoza‐Escobar, Laura Martí‐Sánchez, Fradique Moreira, Miguel Coelho, Leonor Correia Guedes, Ana Castro Caldas, Joaquim J. Ferreira, Paula Pires, Cristina Costa, P Sousa, Marina Magalhães, María Stamelou, Daniel Cuadras, Carmen Rodríguez–Blázquez, Pablo Martínez‐Martín, Vincenzo Lupo, Leonidas Stefanis, Roser Pons, Carmen Espinós, Teresa Temudo, Belén Pérez‐Dueñas,
ABSTRACT Background Pantothenate kinase‐associated neurodegeneration is a progressive neurological disorder occurring in both childhood and adulthood. The objective of this study was to design and pilot‐test a disease‐specific clinical rating scale for the assessment of patients with pantothenate kinase‐associated neurodegeneration. Methods In this international cross‐sectional study, patients were examined at the referral centers following a standardized protocol. The motor examination was filmed, ...
Tópico(s): RNA regulation and disease
2017 - Wiley | Movement Disorders
Antonio Hernández-Vela, Carlo Gatta, Sérgio Escalera, Laura Igual, Victoria Martín‐Yuste, Manel Sabaté, Petia Radeva,
Segmentation of coronary arteries in X-Ray angiography is a fundamental tool to evaluate arterial diseases and choose proper coronary treatment. The accurate segmentation of coronary arteries has become an important topic for the registration of different modalities which allows physicians rapid access to different medical imaging information from Computed Tomography (CT) scans or Magnetic Resonance Imaging (MRI). In this paper, we propose an accurate fully automatic algorithm based on Graph-cuts ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2012 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Information Technology in Biomedicine
Simón Navarro, Nuria Vela, Carlos Garcı́a, Ginés Navarro,
The persistence of two herbicides, simazine and terbuthylazine, and appearance of their principal dealkylated chloro-s-triazine metabolites have been studied in agricultural soil after the addition of urban sewage sludge as organic amendment. Both herbicides and metabolites were monitored during long-term laboratory incubation (140 days) and analyzed by gas chromatography with a nitrogen-phosphorus detector (GC-NPD). Residues were confirmed by gas chromatography with a mass selective detector (GC-MSD). ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2003 - American Chemical Society | Journal of Agricultural and Food Chemistry
Martha Hı́jar, Eduardo Vazquez-Vela, Carlos Arreola‐Risa,
Road traffic injuries in general and pedestrian injuries in particular are a major public health problem in Mexico, especially in large urban areas. Analysis of mortality and road crashes at the national level was done using routine data recorded on death certificates. Fatality rates for different age groups were estimated by region for the year 2000. These data were supplemented by a cross-sectional study of pedestrian injuries in Mexico City based on death certificates information for pedestrians ...
Tópico(s): Trauma and Emergency Care Studies
2003 - Taylor & Francis | Injury Control and Safety Promotion
Juan Carlos Izquierdo Vela ́squez, Angela María Campos Mahecha, Juan Pablo Duarte Silva,
Vela´squez, Juan Carlos Izquierdo; Mahecha, Angela María Campos; Silva, Juan Pablo Duarte Author Information
Tópico(s): Cancer and Skin Lesions
2012 - Lippincott Williams & Wilkins | Otology & Neurotology
Pablo Abellán Galiana, Carmen Fajardo, Pedro Antonio Riesgo Suárez, José Gómez Vela, Carlos Escrivá, Vicente Rovira Lillo,
En el manejo de la enfermedad de Cushing (EC) no existe un consenso sobre los criterios de remisión ni sobre la definición de recurrencia en la literatura, por lo que las series no son comparables. Se ha descrito que la tasa de recurrencia en la EC oscila entre 5-25% en el seguimiento a largo plazo. Dentro de los factores pronósticos de remisión a largo plazo podemos diferenciar: 1) factores dependientes del adenoma (agresividad, tamaño, identificación preoperatoria por técnicas de imagen); 2) factores ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2012 - Elsevier BV | Endocrinología y Nutrición
... This paper draws heavily on a study by Carlos Martinez-Vela (MIT/IPC) and Kimmo Viljamaa as part of ... Vela & Viljamaa, Citation2005). The author wishes to thank Carlos Martinez-Vela for insightful comments and advice. Also, the Finnish ... 2. The interview data was collected together with Carlos Martinez-Vela from IPC/MIT. 3. The study draws on ...
Tópico(s): Conferences and Exhibitions Management
2007 - Taylor & Francis | European Planning Studies
Valeria Vega-Vela, Carlos Alfonso Muñoz Robles, Ernesto Rodríguez‐Luna, Juan Carlos López‐Acosta, Ricardo Serna-Lagunes,
El análisis del paisaje caracteriza la estructura y funcionamiento ecológico, para proponer estrategias de mitigación a los problemas ambientales. El objetivo fue analizar la configuración espacial de elementos del paisaje de la Reserva de la Biosfera Los Tuxtlas (RBLT), a partir de imágenes LANDSAT de 1995, 2006 y 2016. Las cuales fueron rectificadas y clasificadas de acuerdo a los tipos de cobertura y uso de suelo, cada una se analizó con métricas de paisaje mediante el software FRAGSTATS 3.3. ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2018 - Universidad Juárez Autónoma de Tabasco | Ecosistemas y Recursos Agropecuarios
Juan Carlos Yébenes, Carol Lorencio, Elisabeth Esteban, L. Espinosa, Josep M. Badía, Capdevila Ja, Berta Cisteró, S A Moreno, Esther Calbo, Xavier Jiménez-Fábrega, Montserrat Clèries, María Teresa Faixedas, Ricard Ferrer, Emili Vela, Carlos Bravo, Alejandro Rodríguez, C. Netto, E. Armero, Montserrat Simó-Solsona, Rosalba Lopez, A. Granes, V. Perez-Claveria, Antonio Artigas, J Estany,
Sepsis is a syndromic entity with high prevalence and mortality. The management of sepsis is standardized and exhibits time-dependent efficiency. However, the management of patients with sepsis is complex. The heterogeneity of the forms of presentation can make it difficult to detect and manage such cases, in the same way as differences in training, professional competences or the availability of health resources. The Advisory Commission for Patient Care with Sepsis (CAAPAS), comprising 7 scientific ...
Tópico(s): Emergency and Acute Care Studies
2019 - Elsevier BV | Medicina Intensiva (English Edition)
Miguel Á. González‐Gay, Carmen González‐Vela, Carlos González-Juanàtey,
La psoriasis y la artritis psoriásica se asocian con un mayor riesgo de eventos cardiovasculares y de mortalidad cardiovascular. Además de los factores clásicos de aterosclerosis, la gravedad de la afección cutánea influye en el aumento del riesgo cardiovascular en estos pacientes. En ambos procesos se observa la presencia de disfunción endotelial y un grosor aumentado de la íntima-media de la arteria carótida, como expresión de enfermedad cardiovascular subclínica. El tratamiento activo de la enfermedad ...
Tópico(s): Skin Diseases and Diabetes
2012 - Elsevier BV | Actas Dermo-Sifiliográficas
Keiko Taniguchi‐Ponciano, Eduardo Vadillo, Héctor Mayani, César González-Bonilla, Javier Torres, Abraham Majluf, Guillermo Flores, Niels H. Wacher, Juan Carlos Galán, Eduardo Ferat‐Osorio, Francisco Blanco-Favéla, Constantino López-Macı́as, Aldo Ferreira‐Hermosillo, Claudia Ramírez‐Rentería, Eduardo Peña-Martínez, Gloria Silva-Román, Sandra Vela-Patiño, Carlos Mata-Lozano, Roberto Carvente-Garcia, Lourdes Basurto-Acevedo, Renata Saucedo, Patricia Piña‐Sánchez, Antonieta Chávez‐González, Daniel Marrero‐Rodríguez, Moisés Mercado,
COVID-19 counts 46 million people infected and killed more than 1.2 million. Hypoxaemia is one of the main clinical manifestations, especially in severe cases. HIF1α is a master transcription factor involved in the cellular response to oxygen levels. The immunopathogenesis of this severe form of COVID-19 is poorly understood.We performed scRNAseq from leukocytes from five critically ill COVID-19 patients and characterized the expression of hypoxia-inducible factor1α and its transcriptionally regulated ...
Tópico(s): COVID-19 Clinical Research Studies
2020 - Informa | Annals of Medicine
Graciela Pellejero, Karol Adriana Gallardo Rodríguez, G. Ashchkar, E. Vela, Carlos García‐Delgado, Raimundo Jiménez Ballesta,
Tópico(s): Food Waste Reduction and Sustainability
2020 - Springer Science+Business Media | International Journal of Environmental Science and Technology
Pablo Abellán Galiana, Carmen Fajardo, Pedro Antonio Riesgo Suárez, José Gómez Vela, Carlos Escrivá, Vicente Rovira Lillo,
There is no consensus on the remission criteria for Cushing's disease or on the definition of disease recurrence after transsphenoidal surgery, and comparison of the different published series is therefore difficult. A long-term recurrence rate of Cushing's disease ranging from 2% to 25% has been reported. Predictors of long-term remission reported include: (1) adenoma-related factors (aggressiveness, size, preoperative identification in MRI), (2) surgery-related factors, mainly neurosurgeon experience, ( ...
Tópico(s): Adrenal Hormones and Disorders
2013 - Elsevier BV | Endocrinología y Nutrición (English Edition)
Miguel Á. González‐Gay, Carmen González‐Vela, Carlos González-Juanàtey,
Psoriasis and psoriatic arthritis are associated with increased risk of cardiovascular events and cardiovascular mortality. Alongside classic risk factors for atherosclerosis, the severity of psoriatic skin disease also influences cardiovascular risk in these patients. In both cases, endothelial dysfunction and increased intima-media thickness in the carotid artery are indicators of subclinical cardiovascular disease. Active treatment of the psoriasis and management of traditional cardiovascular ...
Tópico(s): Therapeutic Uses of Natural Elements
2012 - Elsevier BV | Actas Dermo-Sifiliográficas
Solène M. Laville, A. Couturier, Oriane Lambert, Marie Metzger, Nicolas Mansencal, Christian Jacquelinet, Maurice Laville, Luc Frimat, Denis Fouque, Christian Combe, Bruce Robinson, Bénédicte Stengel, Sophie Liabeuf, Ziad A. Massy, Carole Ayav, Serge Briançon, Dorothée Cannet, Christian Combe, Denis Fouque, Luc Frimat, Yves-Édouard Herpe, Christian Jacquelinet, Maurice Laville, Ziad A. Massy, Christophe Pascal, Bruce Robinson, Bénédicte Stengel, Céline Lange, Karine Legrand, Sophie Liabeuf, Marie Metzger, Élodie Speyer, Thierry Hannedouche, Bruno Moulin, Sébastien Mailliez, Gaétan Lebrun, Éric Magnant, Gabriel Choukroun, Benjamin Deroure, Adeline Lacraz, G Lambrey, Jean Philippe, Bourdenx, Marie Essig, Thierry Lobbedez, Raymond Azar, Hacène Sekhri, Mustafa Smati, Mohamed Jamali, Alexandre Klein, Michel Delahousse, Christian Combe, Séverine Martin, Isabelle Landru, Éric Thervet, Ziad A. Massy, Philippe Lang, Xavier Belenfant, Pablo Ureña, Carlos Vela, Luc Frimat, Dominique Chauveau, Viktor Panescu, Christian Noël, François Glowacki, Maxime Hoffmann, Maryvonne Hourmant, Dominique Besnier, Angelo Testa, François Kuentz, Philippe Zaoui, Charles Chazot, Laurent Juillard, Stéphane Burtey, Adrien Keller, Nassim Kamar, Denis Fouque, Maurice Laville,
Elevated serum urea levels are common in moderate-to-advanced CKD. Several studies have shown that urea is a direct and indirect uremic toxin, especially with regard to cardiovascular disease. We sought to determine whether serum urea levels are associated with adverse cardiovascular events and death before renal replacement therapy (RRT) in patients with CKD.
Tópico(s): Parathyroid Disorders and Treatments
2022 - Oxford University Press | Nephrology Dialysis Transplantation
Aghilès Hamroun, Élodie Speyer, Carole Ayav, Christian Combe, Denis Fouque, Christian Jacquelinet, Maurice Laville, Sophie Liabeuf, Ziad A. Massy, Roberto Pécoits-Filho, Bruce Robinson, François Glowacki, Bénédicte Stengel, Luc Frimat, Natália Alencar de Pinho, Carole Ayav, Serge Briançon, Dorothée Cannet, Christian Combe, Denis Fouque, Luc Frimat, Yves-Édouard Herpe, Christian Jacquelinet, Maurice Laville, Ziad A. Massy, Christophe Pascal, Bruce Robinson, Bénédicte Stengel, Céline Lange, Karine Legrand, Sophie Liabeuf, Marie Metzger, Élodie Speyer, Thierry Hannedouche, Bruno Moulin, Sébastien Mailliez, Gaétan Lebrun, Éric Magnant, Gabriel Choukroun, Benjamin Deroure, Adeline Lacraz, G Lambrey, Jean Philippe Bourdenx, Marie Essig, Thierry Lobbedez, Raymond Azar, Hacène Sekhri, Mustafa Smati, Mohamed Jamali, Alexandre Klein, Michel Delahousse, Christian Combe, Séverine Martin, Isabelle Landru, Éric Thervet, Ziad A. Massy, Philippe Lang, Xavier Belenfant, Pablo Ureña, Carlos Vela, Luc Frimat, Dominique Chauveau, V Panescu, Christian Noël, François Glowacki, Maxime Hoffmann, Maryvonne Hourmant, Dominique Besnier, Angelo Testa, François Kuentz, Philippe Zaoui, Charles Chazot, Laurent Juillard, Stéphane Burtey, Adrien Keller, Nassim Kamar, Denis Fouque, Maurice Laville,
ABSTRACT Background Conservative care is increasingly considered an alternative to kidney replacement therapy for kidney failure management, mostly among the elderly. We investigated its status and the barriers to its implementation from patients’ and providers’ perspectives. Methods We analysed data from 1204 patients with advanced chronic kidney disease (CKD) [estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2] enrolled at 40 nationally representative nephrology clinics (2013–16) who ...
Tópico(s): Palliative Care and End-of-Life Issues
2022 - Oxford University Press | Nephrology Dialysis Transplantation
Yashwanth Ashok, Carlos Vela‐Rodríguez, Chunsong Yang, Heli I. Alanen, Fan Liu, Bryce M. Paschal, L. Lehtiö,
Ubiquitination and ADP-ribosylation are post-translational modifications that play major roles in pathways including the DNA damage response and viral infection. The enzymes responsible for these modifications are therefore potential targets for therapeutic intervention. DTX3L is an E3 Ubiquitin ligase that forms a heterodimer with PARP9. In addition to its ubiquitin ligase activity, DTX3L–PARP9 also acts as an ADP-ribosyl transferase for Gly76 on the C-terminus of ubiquitin. NAD+-dependent ADP- ...
Tópico(s): Autophagy in Disease and Therapy
2022 - Portland Press | Biochemical Journal
A. Gimeno-Furió, Raúl Martínez‐Cuenca, Rosa Mondragón, Antonio Fabián Vela Gasulla, Carlos Doñate‐Buendía, Gladys Mínguez‐Vega, Leonor Hernández,
Carbon nanoparticles are very useful in solar thermal applications as they absorb much of the solar spectrum and can be inexpensive. Water-based carbon nanofluids with two different concentrations (3 and 33 mg l−1) were prepared with sodium dodecyl sulphate as surfactant to achieve good high-temperature stability with a constant mean particle size of 200 nm at 25 °C and 85 °C. The morphology of the nanoparticles was observed by Transmission Electron Microscopy and the particle size distribution was ...
Tópico(s): Solar-Powered Water Purification Methods
2020 - Elsevier BV | Energy
Ignacio Morales-Burruezo, José-Luis Gandía-Franco, Juan Cobo, Arturo Vela-Hernández, Carlos Bellot‐Arcís,
Background In adult patients, treatment of skeletal crossbite requires combined treatment by fixed or removable appliances and orthognathic surgery. In cases of dentoalveolar crossbite, expansion can be achieved with fixed multibrackets and removable transparent aligners. Various researchers have already assessed the Invisalign system’s predictability for arch expansion. However, most of this research was conducted using older appliances, making it necessary to assess the characteristics of the ...
Tópico(s): Dental Radiography and Imaging
2020 - Public Library of Science | PLoS ONE
Sven T. Sowa, Carlos Vela‐Rodríguez, Albert Galera‐Prat, Mariana Cázares-Olivera, Renata Prunskaitė-Hyyryläinen, Alexander Ignatev, L. Lehtiö,
Abstract Tankyrases catalyse poly-ADP-ribosylation of their binding partners and the modification serves as a signal for the subsequent proteasomal degradation of these proteins. Tankyrases thereby regulate the turnover of many proteins involved in multiple and diverse cellular processes, such as mitotic spindle formation, telomere homeostasis and Wnt/β-catenin signalling. In recent years, tankyrases have become attractive targets for the development of inhibitors as potential therapeutics against ...
Tópico(s): DNA Repair Mechanisms
2020 - Nature Portfolio | Scientific Reports
Cécile Couchoud, Florian Bayer, Carole Ayav, Clémence Béchade, Philippe Brunet, François Chantrel, Luc Frimat, Roula Galland, Maryvonne Hourmant, Emmanuelle Laurain, Thierry Lobbedez, Lucile Mercadal, Olivier Moranne, A. Abbassi, A. Debure, A. Guerraoui, A. Benmoussa, Abdelaziz Hamani, Abdelaziz Ziane, Abdelhamid Nefti, A Hadj, Abderrahim El Amari, Abderrahmane Ghazali, Abo Bakr Abd El Fatah Mohamed, A. Laradi, Adel Ben Ahmed, Adel Sahar, A. Pillet, Adeline Lacraz, Adnan Moinat, Afshin Massoumi, Agathe Pardon, Agnes Caillette Beaudoin, A. Debout, Agnès Mariot, Ahmed Rachi, Aïda Afiani, Aime Remy Boula, Al Jalaby, A. Crémault, A Fournier, Alain Jeanson, A J Lyon, A. Nony, Alain Robert, A Slingeneyer, Alanor Agnes Labatide, Albane Sartorius, A Bensman, Albert Fournier, Alex Ranlin, Alex Vido Sandor, Alexandra Siqueira Colombo, A Turkowski Duhem, A. Stancu, Alexandre Dufay, Alexandre Dumoulin, Alexandre Ébel, Alexandre Klein, Alexandre Martin, A. Mouneimne, Alexandre Seidowsky, A. Martín, Alfredo Zannier, Ali Aizel, Ali Hafi, Ali Zineddine Diddaoui, Alim Heyani, Alina Mocanu, Alina Preda, A Hafi, A Talaszka, Alyette Duquesne, Amar Amaouche, Amel Ghemmour, Amélie Simon, Amina Skalli, Amine Boukadida, Amr Ekhlas Ragab Eid, Ana Fedorca, Anabelle Baillet, Anaïs Poyet, Ancuta Bouffandeau Giorgita, A. Ratsimbazafy, A Pruna, Àngel Argilés, Angelo Testa, Ann Karolien Vandooren, Anne Jolivot, Anne Kolko Labadens, A. Lataste, Anne Maisin, Anne Paris, A. Séchet, Anne Wuillai, Anne Elisabeth Heng, Anne Gaelle Josse, Anne Helene Querard, Anne Helene Reboux, Anne Laure Adra, Anne Laure Faller, Anne Laure Leclerc, Anne Laure Poitou, Annie Lahoche Manucci, Antoine Jacquet, A. Pommereau, Antoine Thierry, Arezki Adem, Arielle Chapelet, Arnaud Del Bello, Arnaud Delezire, Arnaud Garnier, Arnaud Guérard, A Klisnick, Arnaud Lionet, Arnaud Roccabianca, Arnaud Stolz, Arthur Capdeville, Asma Allal, Assem Alrifai, Assetou Diarrassouba, Assia Djema, Assia Ferhat Carre, Astrid Godron Dubrasquet, Atman Haddj Elmrabet, Audrey Jegado, Aurelia Bertholet Thomas, Aurélie Davourie Salandre, Aurélie Pajot, Aurélien Lorthioir, A. Tiple, A. Sury, Ayman Abokasem, Ayman Sarraj, Bachir Henaoui, Baher Chaghouri, Bassem Wehbe, Beatrice Ball, B Viron, Belkassem Issad, Benedicte Hodemon Corne, Bénédicte Janbon, Benjamin Deroure, Benjamin Savenkoff, B. Jonon, Benoı̂t Vendrely, Benyakoub Djelaleddine, Bernard Ohry, Bernard Painchart, Bernard Strullu, B Temperville, B Ebikili, B Hacq, Bertrand Morel, Bilal Aoun, Blanca Muniz, B. Chlih, Brahim Amara, Brice Mayor, B Gilson, Brigitte Llanas, B. Zins, B Bourgeon, B Coevoet, Benoît Guéry, B. Legallicier, Bruno Paris, Bruno Ranchin, Bruno Seigneuric, Camelia Ghiciuc Dita, Camélia Prelipcean, C Hottelart, Carine Diet, C. Frangié, Carlos Vela, Carmina Muresan, Carole Deprele, Caroline Pacheco Araújo, Caroline Bidault, Caroline Créput, Caroline Delclaux, C. Du Halgouet, Caroline Favennec, C. Fréguin, Caroline Vercel, C. Mesguen, Caroline Ndomo Obama, Caroline Poitou, Caroline Preissig Dirhold, Caroline Roubiou, Catherine M. Albert, C. Bessin, Catherine De Marion Gaja, Catherine Godart, Catherine Lasseur, Catherine Leocardi, Catherine Lumbroso, Catherine Melander, Catherine Michel, Catherine Quere Maurouard, Catherine Rouannet, Catherine Taddei, C. Vérove, Cecile Guiraud, Cecile Tafelin, Cecile Turc Baron, C. Formet, Cédric Pinier, Celia Lessore De Ste Foy, C. Granolleras, Chaouki Bennini, Charles Cartou, Charles Chazot, Charlotte Jouzel, Chérif Badid, Christa Roubicek, C Viaud, C S Verrier, C. Chuet, Christian Combe, Christian Dabot, C Duvic, Christian Emond, C Lagarde, Christian Lamotte, C. Pain, Christiane Mousson, Christie Lorriaux, Christine Beauchamp, Christine Fumeron, Christine Le Gurun, Christine Leroy, Christine Piètrement, Christine Richer, Christophe Bouaka, Christophe Charasse, Christophe Goupy, Christophe Ridel, Cindy Castrale, Cindy Detourne, Clair Francois, Claire Presne, Claire Trivin, Clarissa Von Kotze, Claude C.A. Bernard, Claude Bonniol, Claude Desvergnes, Claude Raharivelina, Claudia Andreea Nistor, Claudine Gueret, Claudine Lloret, Claudine Saltiel, C Rosati, Clémentine Rabaté, C. Stanescu, Corinne Ferrandini, Corinne Guibergia, Corinne Lemoine, Corinne Passeron, Cynthia Kahil, Cyril Garrouste, Cyril Vo Van, C Jolimoy, D. Kesraoui, Damien Jolly, Damien Thibaudin, D Teboulle, D Daubresse, Daniel Louvet, Daniel Rasamimanantsoa, Daniel Tolédano, D. Babici, Daniela David, Daniela Dincu, Danielle Bruno, Delia May, Delphine Haussaire, Delphine Henriet Viprey, Denis Bugnon, Denis Fouque, Denis Morin, Derradji Nour, Diab Mohamed Mahmoud, D Cristescu, Didier Aguiléra, Didier Coste, D. Hamel, D. Le Chapois, Didier Testou, Dilaver Erbilgin, Djamal Dahmane, Doan Bui Quang, Dominique Bertrand, Dominique Besnier, Dominique Blanchier, Dominique Briffa,
The aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs ...
Elsevier BV
Ziad A. Massy, Jean Ferrières, Éric Bruckert, Céline Lange, Sophie Liabeuf, Maja Velkovski-Rouyer, Bénédicte Stengel, Carole Ayav, Christian Combe, Denis Fouque, Luc Frimat, Yves-Édouard Herpe, Maurice Laville, Ziad A. Massy, Bénédicte Stengel, Céline Lange, Karine Legrand, Sophie Liabeuf, Marie Metzger, Élodie Speyer, Bruno Moulin, Gaétan Lebrun, Éric Magnant, Gabriel Choukroun, Jean Philippe Bourdenx, Marie Essig, Raymond Azar, Mustafa Smati, Mohamed Jamali, Alexandre Klein, Michel Delahousse, Christian Combe, Séverine Martin, Éric Thervet, Ziad A. Massy, Xavier Belenfant, Pablo Ureña, Carlos Vela, Luc Frimat, Dominique Chauveau, Viktor Panescu, François Glowacki, Maxime Hoffmann, Maryvonne Hourmant, Dominique Besnier, Angelo Testa, Philippe Zaoui, Charles Chazot, Laurent Juillard, Stéphane Burtey, Adrien Keller, Nassim Kamar, Denis Fouque, Maurice Laville,
We describe the characteristics of patients with moderate/advanced chronic kidney disease (CKD) according to receipt of lipid-lowering therapy (LLT), and whether they achieved low-density lipoprotein cholesterol (LDL-C) targets for high- and very high-risk patients.CKD-REIN (NCT03381950), a prospective cohort study conducted in 40 nephrology clinics in France, enrolled 3033 patients with moderate (stage G3) or advanced (stage G4/G5) CKD (2013-2016) who had not been on chronic dialysis or undergone kidney ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2019 - Elsevier BV | Kidney International Reports
Cristina Fernández-Córdoba, Carlos Vela, Mercè Villanueva,
The Z2s-additive codes are subgroups of Z2sn, and can be seen as a generalization of linear codes over Z2 and Z4. A Z2s-linear Hadamard code is a binary Hadamard code which is the Gray map image of a Z2s-additive code. A partial classification of these codes by using the dimension of the kernel is known. In this paper, we establish that some Z2s-linear Hadamard codes of length 2t are equivalent, once t is fixed. This allows us to improve the known upper bounds for the number of such nonequivalent ...
Tópico(s): Advanced Wireless Communication Techniques
2019 - Elsevier BV | Discrete Mathematics