Andrew Robson, James Landale, Paul Stater, Jon Ashworth, Stella Shamoon, Joanna Hunter, Richard Whitehead, Robert Cole, Bud Baldaro, Catherine Riley, Andrew Pierce, Elizabeth Judge and Roland Watson, Grace Bradberry, PH, Jane MacQuitty, Gary Neville, Salome Munuo, Richard Hobson, Dawn Smith, Philip Howard, PS, James Bone, Elizabeth Judge, Michael Kuhn, Richard Irving, James Hassall, Geoffrey H. Lloyd, Sharon Linnard, Mark Court and Jon Ashworth, E. Jane Dickson, john diamond, Readers' Forum, Kevin Eason, James Eve, Thunderer, Antonia Senior, Carl Evans, Ben Webster Transport Correspondent, Martin Barrow Deputy Business Editor, Valerie Elliott Countryside Editor, Ian Sykes, Valerie Elliott, Joseph Koniak, Steve Bird, Ruth Gledhill, Gary Jacob, Sheila Stem, Simone Cameron, Victoria Segal, Jill Dupleix, Ross Dunn, Martin Barrow, Dalya Alberge Arts Correspondent, simon thompson, Libby Purves, John R. Cherry, Candida Crewe, Jo Morris, Mike Rosewell Rowing Correspondent, Andy Stephens, B. Tenpest, David Hands, Charles Bremner, Daniel McGrory and Ben Webster, Helen Rumbelow, Greg Hurst, Peter Barnard, Nicholas Wapshott, Edward Gorman, Caroline Merrell Banking Correspondent, Mark Court, James Urquhart, Gerald Kaufman, Angela Jameson, JJ, Russell Kempson, Alastair McGowan, Daniel McGrory, Bob Hopkins, Jeremy Bremridge, JU, David Lister, E. Chowdharay-Best, Jeremy Beadle, Polly Markandya, Jill Sherman Whitehall Editor, Mark Henderson Science Correspondent, Tom Baldwin, Andrew Pierce and Roland Watson, Chris Power, Russell Kempson George Caulkin and Oliver Kay, Sam Lister Stewart Tendler and Sam Coates, John Hopkins Golf Correspondent, Rob Wright, Brian Maiden, David Powell Athletics Correspondent, Raymond Keene, Vaughan Freeman, Adam Sage, Lewis Smith, Matthew Pryor, Matt Dickinson, Arthur C. Clarke, Cheryl Taylor, Lucy Pinney, Victoria Walker, Paul Wilkinson, Christine Buckley Industrial Editor, Sam Bussey, Martin Short, Sue Darge, Tom Baldwin Roland Watson, Min Cooper, Matthew Cook, Chris Ayres Media Business Correspondent, Emma Miller, Jane Hughes, Oliver Holt, Peter Hutchinson, Fiona Terry, Ross Leckie, Roger Boyes, Clive Barker, Emily Davies, Nick Hasell, Billy Connolly, Chris Keenan, Richard Holledge, Clive Raleigh, David Hands Rugby Correspondent, Steve Jelbert, Tim Reid Emma Daly and Mike Rosewell, Nick Szczepanik, John Goodbody, Steve Bird and Gary Jacob, Diana Ceddes, RL, Giles Whittell, Mike Brewer, Paul McCann Media Correspondent, Deborah King, Matthew Parris, Graham Searjeant Financial Editor, Jennai Cox, PB, Mark Hodkinson, Pieter L. Rondeboom, Chris McGrath, Russell Jenkins, Peter Riddell, DC, Genevieve Douglas, Mark Henderson Science Correspondent and James Pringle, David Holloway, Matthew Redhead, W. A. C. Halliwell, Richard Miles, Annabelle Thorpe, Martin Waller, Tom Baldwin and Stewart Tendler, Fran Littlewood, Carl Mortished International Business Editor, James Jackson, Laura Peek, Jill Crawshaw, David Powell, Lewis Smith and Ray Kennedy, Tom Baldwin Deputy Political Editor, Fiona Beckett, Denis R. Alexander, John Phillips, Rachel Pearson, Peter Roebuck, Roland Watson and Tom Baldwin, Mick Burke, Susan Emmett,
... Bill Elliot Picture Gallery no title Director: Sam Mendes (18 ) Stars: Kevin Spacey,… December 30 - January 5 ...
2000 - Gale Group | TDA
Produção Nacional
Revisado por pares
Bárbara Bruna Ribeiro Oliveira-Mendes, Carolina Campolina Rebello Horta, Anderson Oliveira do Carmo, Gabriela Lago Biscoto, Douglas Ferreira Sales-Medina, Hortênsia Gomes Leal, Pedro F. P. Brandão‐Dias, Sued Eustáquio Mendes Miranda, Carla Aguiar, Valbert Nascimento Cardoso, André Luís Branco de Barros, Carlos Chávez-Olórtegui, M. Fátima Leite, Evanguedes Kalapothakis,
Scorpion sting envenoming impacts millions of people worldwide, with cardiac effects being one of the main causes of death on victims. Here we describe the first Ca2+ channel toxin present in Tityus serrulatus (Ts) venom, a cell penetrating peptide (CPP) named CPP-Ts. We show that CPP-Ts increases intracellular Ca2+ release through the activation of nuclear InsP3R of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells. Besides proposing a novel subfamily of Ca2+ ...
Tópico(s): Venomous Animal Envenomation and Studies
2018 - Nature Portfolio | Scientific Reports
Selwyn Hodson Pressinger, M. Downes, Jagjit Gupta, Waldemar Januszczak, John Dugdale, I Cameron, Mark Franchetti muzaffarabad, Barbara Hall, Nick Compton, Jonathan Glayton, Tony Matthews WBA club historian and statistician, Nigel Botherway, N J, Fred Redwood, Chandrika Kumaratunga, David Brown, Graham Brooks, Mary Killen, Helen Davies, Nicholas Rufford, Peter Whittle, Rob Hughes, John Leslie, John Peter, V S, Amanda Ursell, John Doughty, Miranda Nugent, Charles Miranda, Jonathan Miller, Karen Wheeler, Jane Mulkerrins, Julia Phillips, J D, Max Glaskin, Emine Saner, Alan Delaney, Frank Whitford, Ivo Tennant, Alex Todorovic, Nicola Venning, Kathryn Cooper, Frankie Dettori, John Elliot, Sam Gilpin, P D, David Smith, Humphrey Carpenter, Tim Richards, Rory Godson, David Schwartz, David Cracknell Political Editor, Jonathan Wynne-Jones, Dr Charles Chillcott, David Lynch, E P, Clive Davis, Anne Munro, Bob Pawsey, Sue Leonard, Joseph Dunn, John Dugdate, Simon Wilde, Martin James, Tom Walker, Sir Christopher Bland, Robert Winnett, Irwin Stelzer, Jane Moore, Tom English, Matt Rudd, Peter Wilson, Rosie Millard, Robert Hewison, Charlotte Wolff, David Dougill, Fran Babb, Marty Bandier, Geraldine Hackett, H C, David Hewson, Cally Law, Peter Yates, Jonathon Carr-Brown, Margarette Driscoll, Alasdair Reid, Geraldine Hackett Education Correspondent, Alan Nicol, Jeremy Clarkson, Stewart Lee, Edward Porter, Dr Peter Daggett Consultant Physician, Hugh Canning, Louise Taylor, David Cairns, Victoria Segal, Max Anderson, Helen Kirwan, Martin Rees, Michael Jones, John O'Donnell, Lacasta Miller, Henry Wasswa, Richard Fletcher, Phil Craigle, James Clarke, Sam Murphy, George Perry, Mike Ganley, Adam Nathan, Philp Kingsley, David Landes, Naoml Calne, Stuart Wavell, Paul Donovan, Alastair Hendy, Steve Boyd, Lucinda Kemeny, Jasper Gerard, Paul Driver, Lucy Moore, Garth Pearce, John Humphrys, Patrick Garratt, Nicholas Hellen, John Follain, Gheryl Markosky, Shelley Von Strunckel, Joe Lovejoy football correspondent, Alex Clark, Christopher Morgan, David Leppard, Amber Cowan, R Kolesar, Tom Lloyd, Stephen Hayllar, Mark Edwards, Susan Clark, David Lawrenson, Danny O'Brien, William Dixon Smith, G Murphy, Phil Baker, Christina Patterson, Victoria O'Brien, Lois Rogers, Peter isles, Roy Harrison, Alan Stockwell, Ken Barnes, Andy Matthews, Wembley Arona, Steven Boyd, Chloë Beeney, Gareth Huw Davies, Raymond Keene, David Reith, David Cracknell, Senay Boztas, Uki Goni, Zoe Brennan, Cosmo Landesman, Tim Richardson, Allcia Wyille, William Peakin, J R R Tolklen, Andy Knott, Marina Cantacuzino, Chris Partridge, Dominic O'Connell, Stephen Jones, Richard Evans, Nick Cain, Michael Wright, Kate Rew, M J, G Watson, Tim Moorey, kevin Maguire, Keith Wheatley, Miranda Seymour, David Walsh, Mandy Francis, Bryan Appleyard, Stephen Armstrong, John Elliott, Ron Clarke, John Richardson, Roland White, Peter Harrison, Joseph Sinclair, Rory Godson Business Editor, Lee Johnson, Brian Ford, William Ells, Ian Rankin, Maurice Chittenden, Bernard Russell, Richard Brooks Arts Editor, Jim Nolan, Richard Rae, Ray Hutton, Iain Stewart-Fergusson, Peter Witson, Martin Ivens, Jenny Uglow, Susan Elkin, Bill Gamble, Amanda Craig, Dr Mustafa Iqbal, John Harlow, Jamie Bye, Godfrey Smith, Robert Winnett Consumer Affairs Correspondent, Barry Collins, Dipesh Gadher, Matthew Campbell, Brian Glanville, John Sorrell, John Carey, Gregor Watt, Natalle Graham, Tom Robbins, Stephen Pettitt, Claudia Croft, Maria McErlane, Jonathan Calvert, Hazel Curry, Jason Corcoran, Tom Walker Diplomatic Correspondent, Sally Kinnes, Nigel Powell, Mark Haughton, David Wickers, Roger Dobson, M Radha, Jeremy Lazell, John Cornwell, Mark Hodson, Graham Norwood, Joe Lovejoy, R Masters, Rupert Steiner, John Appleyard, David Budworth, Hugh Pearman, Frank Futzgibbon, Dan Cairns, Pete Oliver, Julian Ryall, Kevin Maguire, David Walsh Sports writer, Martin Culverwell, John Alzlewood, David Smith Economics Editor, Penny Perrick, Simon Crerar, Sarah Baxter, Douglas Kennedy, Rhona Mogridge, Matthew Goodman, India Knight, Joanna Simon, Steve Grant, Kingston Smith, Ben West, Danny Danziger, Barry Newcombe, Dominic Rushe, Boris Schapiro, Karen Robinson,
... Island Discs celebration, Roots Manuva, Sheryl Crow, Sam Mendes and the life of All. . . Over the next ...
2002 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Cristina Brandt Friedrich Martin Gurgel, Armando Miguel, Clayde Regina Mendes, Carolina Okada Zerbini, Thiago Mussato Carcioni,
To assess the frequency of hypertension in chagasic patients, as well as its clinical behavior and cardiologic findings.We carried out a retrospective study with 225 patients with chronic Chagas' disease and hypertension (104 males), mean age of 55.1 11.8. These patients were being followed up in the outpatient care clinics from 1984 to 2000. The study assessed the clinical, electrocardiographic, and radiological viewpoints.Of the 225 hypertensive patients (prevalence = 33.3%), 78 (34.7%) had mild hypertension, ...
Tópico(s): Lysosomal Storage Disorders Research
2003 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
BY OUR LABOUR REPORTER, FROM A CORRESPONDENT, FROM OUR SPECIAL CORRESPONDENT, BY OUR AGRICULTURAL CORRESPONDENT, BY OUR SPECIAL CORRESPONDENT, FROM OUR CORRESPONDENT, From Our Own Correspondent, FROM OUR OWN CORRESPONDENT, FROM OUR UNITED NATIONS CORRESPONDENT, SIR SYDNEY CAINE, , FROM OUR AERONAUTICAL CORRESPONDENT, BY OUR PARLIAMENTARY CORRESPONDENT, From Our Correspondent, By Our Labour Reporter, STANLEY UNWIN., J. W. Y. HIGGS., J. E. S. SIMON., RICHARD EVELY., DAVID C. MARSH, , L. H. SALTER, , From Our Special Correspondent lately in Eastern Germany, EDWARD DE STEIN., M. HARTLAND THOMAS, , D. CLEMENT BURGESS., MARY A. PARSONS., G. PERCY HARRIS., BY WILSON HARRIS, Sir Gerald Kelly, P.R.A., , R. M. S., H. E. C., and J. J. C., FROM OUR CRICKET CORRESPONDENT, FROM OUR RACING CORRESPONDENT, FROM OUR HOCKEY CORRESPONDENT, FROM OUR RUGBY FOOTBALL CORRESPONDENT, FROM OUR LAWN TENNIS CORRESPONDENT,
... Of Turkish Journalists Criticism Of "The Times", M. Mendès-France Addresses Party Personal Triumph, Adjustments To Trieste ...
1954 - Gale Group | TDA
Produção Nacional
Revisado por pares
Mirian Machado Mendes, Carolina Ferreira de Oliveira, Daiana Silva Lopes, Luis Henrique Ferreira do Vale, Tânia M. Alcântara, Luíz Fernando Moreira Izidoro, Amélia Hamaguchi, Maria I. Homsi-Brandeburgo, Andreimar M. Soares, Veridiana de Melo Rodrigues,
Abstract Many medicinal plants have been recommended for the treatment of snakebites. The aqueous extracts prepared from the leaves of Schizolobium parahyba (a plant found in Mata Atlantica in Southeastern Brazil) were assayed for their ability to inhibit some enzymatic and biological activities induced by Bothrops pauloensis and Crotalus durissus terrificus venoms as well as by their isolated toxins neuwiedase (metalloproteinase), BnSP‐7 (basic Lys49 PLA 2 ) and CB (PLA 2 from crotoxin complex). Phospholipase ...
Tópico(s): Rabies epidemiology and control
2008 - Wiley | Phytotherapy Research
Natasha Fairweather, Phil Yates, Tunku Varadarajan, David Adams, Paul Heiney, Joanna Hunter, Jonathan Goodall, Nick Nuttall, Brian Greer, Kevin Ferrie, Nicholas Goodison Chairman, Grace Bradberry, V. A. Willetts, Christopher M. Rogers, Jane MacQuitty, Simon Barnes, John Morgan, Chris Powlson, Paul Hoggart, Mark Souster, John Walton, David Rhys Jones, John Diamond, Gavin Lumsden, Raymond Snoddy, Media Editor, Clare Fullerton, Carol Midgley, Ian Murray, John Bird, Patrick Collinson, Robert Findlay, Michael Bracewell, Vinay K. Samuel, Anna Reid, Lynne Truss, Carl Mortished, John E. Strafford, Tony Patrick, Kevin Eason, Margareta Pagano, Clare Stewart, Lawrence Dallaglio, Deirdre Shields, Valerie Elliott, Robert Sheehan, D. R., Steve Keenan, Stewart Tendler Crime Correspondent, Paul Abse, Dominic Walsh, Ruth Gledhill, Raymond Keene Chess Correspondent, Tony Keable-Elliott, Patricia Weiler, Phil Redmond, Carol Price, Ruth Gledhill Religion Correspondent, Mrs Ulrike Rawson, R. K., Alan Hamilton, Lord Montagu of Beaulieu, Nicholas Watt, Alain Berliner, Robert Bruce, Michael Clark, T. P., Anthony Fuller Chairman, Alan Ashley, Harry Ritchie, Sue Corbett, Frances Bissell, David Hands, Caroline Merrell and Clare Stewart, P. B., Sarah Jones, Michael Cable, Martin Symington, Peter Barnard, Joe Wignall, David Charter, Derwent May, Jasper Gerard, Russell Kempson, Lizanne Rose, John Ardagh, Stephen Anderton, Paul Durman, Sarah Johnson, W. C. F. Butler, Lisa Grainger, Sarah Vine, Frank Leboeuf, Frances Gibb and Nicholas Watt, Martin Fletcher, Chief Ireland Correspondent, John Mendes, John Hopkins Golf Correspondent, E. Haughton, Adrienne Burgess, Christopher Thomas and Jill Sherman, Adam Jones, Raymond Keene, Vaughan Freeman, Simon Freeman, Adam Sage, David Robinson, Emma Wilkins, Matt Dickinson, P. W., James Allcock, Arabella Warner, Caroline Merrell, Robin Neillands, Bronwen Maddox, Tom Jackson, Michael Osborne, Oliver Holt, Grace Bradberry, Style Editor, Damian Whitworth, John Givens, Charles Wheeler, Roger Boyes, Sarah Cunningham, David Prosser, Oliver August, Paul Gotch, Dalya Alberge, Christopher Hurst, James Hargraves, Christopher Thomas, Nick Szczepanik, Anne Ashworth, Dominic Kennedy, John Lloyd, Jack Crossley, David Churchill, Elizabeth Nutman, Giles Whittell, Philip Webster Political Editor, Christopher Walker, David Rudnick, Jane Shilling, Jason Nissé, Mel Webb, Lord Irvine, Kevin McCarra, Deborah King, Malcolm McKeag, Richard Evans Racing Correspondent, Mark Hodkinson, Amanda Craig, Chris McGrath, Tim Wapshott, Laurance Martin, Russell Jenkins, Keith Blackmore, Simon Brandenburger, Jane Owen, Donald Watt, Ben MacIntyre, Helen Pridham, Frances Lass, Philip Webster, Richard Miles, John Naish, Fraser Nelson, Graham Searjeant, Anne Ashworth Personal Finance Editor, Chris Ayres, Douglas Gay, Danny Baker, Benedict Nightingale, Tom Rhodes, Jonathan Meades, Marianne Curphey, David Powell, Tom Chesshyre, Valerie Grove, Michael Evans, Robert Whymant, Tony Kelly, Richard Miles Banking Correspondent, Susannah Jowitt, Paul Richardson, Hazel Spink, David Hands, Rugby Correspondent, Colin McQuillan, Ganesh Lall, Alasdair Murray, Economics Correspondent, Sheila Rowbotham, Edward Marriott, Christopher Irvine, Susan Emmett,
... Loyalists attack Bill to tackle Ulster parades Santa Carolina Mrs Osborne I looks back Maybe his notes ...
1997 - Gale Group | TDA
Produção Nacional
Revisado por pares
Marcelo A. Lima, Timothy R. Rudd, Eduardo Henrique Cunha de Farias, Lyvia F. Ebner, Tarsis F. Gesteira, Lauro Mera de Souza, Aline Mendes, Carolina R. Córdula, João Roberto Maciel Martins, Debra Hoppensteadt, Jawed Fareed, Guilherme L. Sassaki, Edwin A. Yates, Ivarne L.S. Tersariol, Helena B. Nader,
The year 2007 was marked by widespread adverse clinical responses to heparin use, leading to a global recall of potentially affected heparin batches in 2008. Several analytical methods have since been developed to detect impurities in heparin preparations; however, many are costly and dependent on instrumentation with only limited accessibility. A method based on a simple UV-scanning assay, combined with principal component analysis (PCA), was developed to detect impurities, such as glycosaminoglycans, ...
Tópico(s): Heparin-Induced Thrombocytopenia and Thrombosis
2011 - Public Library of Science | PLoS ONE
Jac Nasser, Waldemar Januszczak, John Dugdale, Michael Prescott, Nigel Bennett, John Papworth, Paul Theroux, Matthew Wall, Guy Erwood, Tony Barrell, Francois Pienaar, Jim Munro, Sean O'Brien, James Clark, Nicholas Rufford, Eloise Wylie, John Peter, Dan Pearson, Pam Barrett, Amanda Ursell, Mrs Ceri Brooks, John Jay, J D, Susan d'Arcy, Topsy-Turvy, Max Glaskin, Frank Whitford, Edna Weiss, Stephen Pettit, Sam Gilpin, Alistair Scott, Sally Payne, David Smith, Kirstie Hamilton City Editor, Humphrey Carpenter, Chris Dignan, Melanie Phillips, Dr Gordon Bowker, Nick Pitt, Frederic Raphael, E P, Neil Wormald, Andrew Sullivan, Clive Davis, Stephen Grey, Mary Wilson, Tony Allen-Mills, Simon Wilde, David Cairms, Martin James, Tom Walker, Anthony Sattin, Alison Brace, Catriona Woolner, Robert Winnett, Kevin Carter, Irwin Stelzer, Jeremy Seal, Tom English, Peter Wilson, Roger Anderson, David Dougill, David Summer Smith, York Membery, Audrey Bronstein, John Evans, Andrew Summer, Norman Brindley, Steve Curry, Sarah Toyne, David Hewson, Mary Wllson, Tania Alexander, Graham Ramsay, Margaret Coles, L Sequeira Surrey, Margarette Driscoll, Hugh Canning, Peter Watson, Jeremy Clarkson, Don Campbell, Juliette Terzieff, Nigel Williams, Stewart Lee, Louise Taylor, Brain Glanville, Edward Porter, Max Anderson, Alan Brownjohn, John Andrews, Eben Black, Michael Jones, Corwen, Kevin Jackson, Banbury, Nick Gardner, Alan Parr, Phillip Oppenheim, Stuart Wavell, Aude van Ryn, Josephine Smit, Paul Donovan, Alastair Hendy, Susan Clark Health Journalist, Paul Driver, Clare Colvin, Boris Schapiro, Garth Pearce, John Humphrys, Maeve Sheehan, Nicholas Hellen, Richard Brooks, K Barlow, John Follain, Steven Downes, Jerome Burne, Shelley Von Strunckel, Jake Katborg, Richard Black, Mark Edwards, Kirstie Hamilton, David Lawrenson, Chris Smith, Danny O'Brien, Phil Baker, Michael Riding, B Goddard, Steven Boyd, Alan Combes, George Wood, Raymond Keene, Warren Mitchell, Gareth Huw Davies, John Brown, Madeira, Senay Boztas, Cosmo Landesman, Marie Colvin, Brigid McConville, Diana Wright, Andy Knott, Chris Partridge, Michael Prescott Political Editor, Guy Bellairs, Stephen Jones, Uzi Mahnaimi, Peta Bee, Rachel Forder, Alastair McLeod, M J, Dominic Rushe, Sam Mendes, Sir Edward Heath, Rob Ryan, Jemimah Bailey, Claire Oldfield, Xavier Young, David Walsh, Nick Scheele, Martin Robinson Director, Jack Grimston, Bryan Appleyard, Lois Rogers Medical Correspondent, Stephen Armstrong, Ron Clarke, Christopher Goodwin, Josh Salzmann, R W Johnson, George Walden, Richard Woods, Garth Alexander, Simon Finch, Rev John Root, Kim Fletcher, Maurice Chittenden, Alex Fortune, Kevin Pratt, Steve Driver, Richard Brooks Arts Editor, Andrew Lorenz Business Editor, Richard Rae, Ray Hutton, Funchal, Jonathan Powell, Jon Ungoed-Thomas, Susan Elkin, Abi Daruvalla, Jennai Cox, Margaret Cook, Michael Sheridan, John Crossland, Christine Webb, Margaret Walters, Alison Steed, John Harlow, Godfrey Smith, Mark Pearson, Dipesh Gadher, Pam Hendicott, John Waples, Terry Murden, A A Gill, Matthew Campbell, Brian Glanville, Tom Robbins, Martin Cohen, Nick Fielding, Jonathan Leake Science Editor, Karen MacGregor, Jeremy Langmead, Sally Kinnes, Alan English, Andrew Lorenz, Naomi Caine, Nigel Powell, David Wickers, Hazel Courteney, Roger Dobson, Tom Rhodes, John Aizlewood, Bennita King, Simon Carnell, Andrew Frankel, Joe Lovejoy, Ray Perry, Rupert Steiner, Hugh Pearman, Dan Cairns, Alistair Sinclair, Jay Hawkins, David Parsley, John Read], David Smith Economics Editor, Penny Perrick, Tom Deveson, Simon Crerar, Bob Dwyer, Joanna Simon, David McClintick, Steve Grant, Barry Newcombe, Rosie Waterhouse, Gabriella Bianchi, Karen Robinson,
... Dallaglio,… Bush bounces back with win in South Carolina Contents £500,000 windfall for shares row editor ...
2000 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Thiago Barbosa Cahú, Suzan Diniz Santos, Aline Mendes, Carolina R. Córdula, Suely F. Chavante, Luiz B. Carvalho, Helena B. Nader, Ranilson de Souza Bezerra,
Shrimp head waste is a major byproduct of crustacean processing in North-eastern Brazil and represents an interesting source of bioactive molecules. Additionally, its use increases the sustainability of processing fishery products. The present study reports a process developed for recovering bioactive molecules from shrimp heads through autolysis. A protein hydrolysate (120 ± 0.4 g) formed by a 9% (w/v) solution was recovered and lyophilized from 1 kg of shrimp heads. Approximately 195 ± 0.5 mg of carotenoids ...
Tópico(s): Nanocomposite Films for Food Packaging
2011 - Elsevier BV | Process Biochemistry
Produção Nacional
Revisado por pares
Carlos Rafael Borges Mendes, Carolina Sá, João Vitorino, Carlos Borges, Virgínia Maria Tavano, Vanda Brotas,
Tópico(s): Microbial Community Ecology and Physiology
2011 - Elsevier BV | Journal of Marine Systems
Linda Papa, Matthew E. Mendes, Carolina F. Braga,
Mild traumatic brain injury (TBI) is an unfortunately common occurrence in the elderly. With the growing population of older adults in the United States and globally, strategies that reduce the risk of becoming injured need to be developed, and diagnostic tools and treatments that may benefit this group need to be explored. Particular attention needs to be given to polypharmacy, drug interactions, the use of anticoagulants, safety issues in the living environment, elder abuse, and alcohol consumption. ...
Tópico(s): Traumatic Brain Injury Research
2012 - Springer Nature | Current Translational Geriatrics and Experimental Gerontology Reports
Produção Nacional
Revisado por pares
Geraldo Mendes dos Santos, Ana Carolina Mendes dos Santos,
NO PRESENTE trabalho é feita uma síntese dos conhecimentos sobre a atividade pesqueira na Amazônia, incluindo histórico, potencial e tipos de pesca, composição do pescado e principais entraves e estratégias de manejo adotadas. Discute-se a inter-relação da pesca com as condições do ambiente aquático e a importância da vegetação ripariana ou mata ciliar como fonte de alimento, abrigo e refúgio para os peixes. Defende-se a idéia de que o manejo dos recursos pesqueiros só será bem-sucedido e eficaz ...
Tópico(s): Indigenous Health and Education
2005 - UNIVERSIDADE DE SÃO PAULO | Estudos Avançados
Produção Nacional
Revisado por pares
Anderson Oliveira do Carmo, Bárbara Bruna Ribeiro Oliveira-Mendes, Carolina Campolina Rebello Horta, B F Magalhães, Almeida Dantas, Lucas Martins Chaves, Carlos Chávez-Olórtegui, Evanguedes Kalapothakis,
Tityus serrulatus is a Brazilian scorpion species with great medical significance. While the effects of neurotoxins have been extensively studied, little is known about the proteases expressed in the venom gland of this arthropod. In this study, clones from a T. serrulatus (Ts) venom gland cDNA library were selected according to homology to proteases. The sequences were aligned in the database and classified by homology. Similarity and identity analyses of the sequences were carried out, and a phylogenetic ...
Tópico(s): Leech Biology and Applications
2014 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Adriana Bin, Cecilia Gianoni, Paule Jeanne Vieira Mendes, Carolina Thaís Rio, Sergio Salles-Filho, Luiza Maria Capanema,
This paper discusses the institutional reorganization that has culminated in new designs for the management models of Public Research Institutes (PRIs), comparing the experiences of four PRIs in the agricultural sector to identify common elements and differences in processes, flows and policies.The focus is to improve research and innovation management, developing new approaches and tools.
Tópico(s): Science, Technology, and Education in Latin America
2013 - Alberto Hurtado University | Journal of technology management & innovation
Fabiana Rocha-Mendes, Carolina Lima Neves, Rodrigo de Almeida Nobre, Renato Marques, Gledson Vigiano Bianconi, Mauro Galetti,
This study presents data on the composition and species richness of non-flying mammals in the northern part of the Parque Estadual da Serra do Mar, called Núcleo Santa Virgínia (NSV - around 17000 hectares of Atlantic Forest), São Paulo state, southeastern Brazil. The species list was based on ca. 660 km of line-transects, 25512 hours of cameras traps, 7740 trap.nights for small mammals, and 394 track-station.days, as well as occasional records and registers from local people (period 2002 to 2009). ...
Tópico(s): Wildlife-Road Interactions and Conservation
2015 - Fundação de Amparo à Pesquisa do Estado de SP | Biota Neopropica/Biota Neotropica
Produção Nacional
Revisado por pares
Juliana Nunes Vieira, F. S. Maia Filho, G. F. Ferreira, Josiara Furtado Mendes, Carolina Lambrecht Gonçalves, Marcos Marreiro Villela, Daniela Isabel Brayer Pereira, Patrícia da Silva Nascente,
The fast anthelmintic resistance development has shown a limited efficiency in the control of animal's endoparasitosis and has promoted research using alternative control methods. The use of chemicals in animal anthelmintic treatment, in association with nematophagous fungi used for biological control, is a strategy that has proven to be effective in reducing the nematode population density in farm animals. This study aims to verify the in vitro susceptibility of the nematophagous fungi Arthrobotrys ...
Tópico(s): Mollusks and Parasites Studies
2016 - Instituto Internacional de Ecologia (Brazil) | Brazilian Journal of Biology
Milena Paneque, Joana Félix, Álvaro Mendes, Carolina Lemos, Susana Lêdo, João Silva, Jorge Sequeiros,
Introduction: The national protocol of genetic counselling and pre-symptomatic testing for late-onset neurological diseases began in Portugal in 1995. Initially, it was accessible only to adults at-risk for Machado-Joseph disease, but was later extended to other hereditary ataxias, to Huntington’s disease and to familial amyloid polyneuropathy caused by Val30Met mutation at the transthyretin gene. The aim of this study was to describe the profile of the population seeking pre-symptomatic testing, ...
Tópico(s): Ethics in Clinical Research
2019 - Ordem dos Médicos | Acta Médica Portuguesa
Produção Nacional
Revisado por pares
Charles Marques Lourenço, André Luiz Santos Pessoa, Carmen Curiati Mendes, Carolina Rivera‐Nieto, Diane Vergara, Mónica Troncoso, Emily Gardner, Francisca Mallorens, Lina Marcela Tavera, Luis Arturo Lizcano, Nora Atanacio, Norberto Guelbert, Norma Spécola, Nury Mancilla, Carolina Fischinger Moura de Souza, Sara Mole,
Neuronal ceroid lipofuscinosis type 2 (CLN2) disease is an autosomal recessive inherited neurodegenerative lysosomal storage disorder caused by deficient tripeptidyl peptidase 1 (TPP1) enzyme, leading to progressive deterioration of neurological functions commonly occurring in children aged 2-4 years and culminating in early death. Atypical cases associated with earlier or later symptom onset, or even protracted course, have already been reported. Such variable manifestations may constitute an additional ...
Tópico(s): Calcium signaling and nucleotide metabolism
2020 - Wiley | Journal of Paediatrics and Child Health
Produção Nacional
Revisado por pares
Larissa Albuquerque de Oliveira Mendes, Carolina Sousa Ponciano, Allan Henrique Depieri Cataneo, Pryscilla Fanini Wowk, Juliano Bordignon, Heveline Silva, Mauro V. de Almeida, Eloah P. Ávila,
Flavonoids are natural products widely recognized for their plurality of applications such as antiviral, antiproliferative, antitumor activities and, antioxidant properties. The flavanone naringenin is presented in citrus fruits and has been studied to combat recurrent diseases that still lack effective treatment. Research groups have been investing efforts to the development of new, safe and active candidates to combat these agents or conditions and despite good results recently reported against ...
Tópico(s): Insect Pest Control Strategies
2020 - Elsevier BV | Chemico-Biological Interactions
Produção Nacional
Revisado por pares
Vidal Haddad, Adriana Lúcia Mendes, Carolina Talhari, Hélio Amante Miot,
Urbanization, pollution and the modification of natural landscapes are characteristics of modern society, where the change in human relations with the environment and the impact on biodiversity are environmental determinants that affect the health-disease relationship. The skin is an organ that has a strong interface with the environment and, therefore, the prevalence patterns of dermatoses may reflect these environmental changes. In this article, aspects related to deforestation, fires, urbanization, ...
Tópico(s): Entomological Studies and Ecology
2021 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Ricardo Patiño, David Salazar‐Valenzuela, Evencio Joel Medina‐Villamizar, Bruno Mendes, Carolina Proaño‐Bolaños, Saulo L. da Silva, José R. Almeida,
Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includes Ecuadorian territories. It comprises a large distribution, which could contribute to the genetic and venomic variation identified in the species. The high variability and protein isoform diversity of its venom are of medical interest, since it can influence the clinical manifestations caused by envenomation and its treatment. However, in Ecuador there is insufficient information on the diversity ...
Tópico(s): Rabies epidemiology and control
2021 - Elsevier BV | Toxicon
M.J. Cavaco, Celeste Alcobia, Bárbara Oliveiros, Luís Alcides Mesquita, Aurora Carvalho, Fernando Matos, José Miguel Carvalho, Miguęl Villar, Raquel Duarte, João Mendes, Carolina Ribeiro, Carlos Robalo Cordeiro, Fernando Regateiro, Henriqueta Coimbra Silva,
Drug-induced liver injury (DILI) is an unpredictable and feared side effect of antituberculosis treatment (AT). The present study aimed to identify clinical and genetic variables associated with susceptibility to AT-associated hepatotoxicity in patients with pulmonary tuberculosis treated with a standard protocol. Of 233 patients enrolled, 90% prospectively, 103 developed liver injury: 37 with mild and 66 with severe phenotype (DILI). All patients with mild hepatitis had a RUCAM score ≥4 and all patients ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2022 - Multidisciplinary Digital Publishing Institute | Journal of Personalized Medicine
Cledilson Souza Mendes, Fernanda Carolina Mendes da Silva, Mônica da Silva Varges, Marcelo Augusto Mota Brito,
INTRODUÇÃO: Medicamentos prescritos e adquiridos pela população acabam acumulando-se nas residências. Sobras de medicamentos ocorrem por diferentes fatores, como a distribuição de amostras-grátis, a dispensação em excesso, a mudança na terapia, a interrupção ou abandono do tratamento, a cura da doença ou o óbito do paciente, o vencimento do prazo de validade do medicamento, entre outros.OBJETIVO: descrever estratégias para evitar o desperdício de medicamentos realizadas no Brasil, com ênfase na ...
Tópico(s): Palliative and Oncologic Care
2021 - Brazilian Journal of Development | Brazilian Journal of Health Review
R. Koch, Ana Carolina Mendes de Gonzales, E. Witt,
A study was made of the relationship between changes in dentofacial or alveolar structures and soft tissue profile in 113 successfully treated orthodontic patients. Linear and angular measurements were made of lateral skull radiographs and profile photographs of 90 Class II Division 1 cases and 23 Class III cases. Similar measurements were carried out on records of 17 non-treated male patients who served as a control. There was a considerable change in soft tissue profile in all the groups studied, ...
Tópico(s): dental development and anomalies
1979 - Oxford University Press | European Journal of Orthodontics
Produção Nacional
Ciro Leite Mendes, Lívia Carolina Santos Vasconcelos, Jordana Soares Tavares, Silvia Borges Fontan, Daniela Coelho Ferreira, Lígia Almeida Carlos Diniz, Elayne Souza Alves, Erick José Morais Villar, César de Farias Albuquerque, Sérgio Luz Domingues da Silva,
OBJETIVO: O objetivo principal deste estudo foi comparar o desempenho das escalas de sedação de Ramsay e Richmond em pacientes críticos sob ventilação mecânica em um hospital universitário. MÉTODOS: Estudo prospectivo onde foram incluídos todos os pacientes sob ventilação mecânica com pelo menos 48 horas de internação, durante quatro meses, totalizando 45 pacientes. Foram avaliados diariamente a modalidade de sedação, dose dos sedativos e analgésicos e o nível de sedação através das escalas de Ramsay ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2008 - Associação de Medicina Intensiva Brasileira | Revista Brasileira de Terapia Intensiva
Produção Nacional
Revisado por pares
Alexandre S. Viola, Daniela Gouveia, Liliana Aparecida Lucci De Angelo Andrade, José Mendes Aldrighi, Carolina F.M. Viola, Luís Bahamondes,
Obesity is a public health problem and it is necessary to identify if non-symptomatic obese women must be submitted to endometrial evaluation.To determine the prevalence of endometrial hyperplasia and cancer in non-symptomatic overweight or obese women.A cross-sectional study was carried out in 193 women submitted to an endometrial biopsy using a Pipelle de Cornier. The findings were classified as normal, hyperplasia or cancer, and the results were compared to body mass index (BMI; kg/m(2)). For ...
Tópico(s): Gynecological conditions and treatments
2008 - Wiley | Australian and New Zealand Journal of Obstetrics and Gynaecology
Produção Nacional
Revisado por pares
Mireille Ângela Bernardes Sousa, Edilberto Nogueira Mendes, Ana Carolina Morais Apolônio, Luiz de Mácêdo Farias, Paula Prazeres Magalhães,
Sousa MÂB, Mendes EN, Apolônio ACM, Farias LM, Magalhães PP. Bacteriocin production by Shigella sonnei isolated from faeces of children with acute diarrhoea. APMIS 2010; 118: 125–35. Shigella is a common agent of diarrhoea, a worldwide major health problem. The bacterium produces bacteriocins; however, the role of these substances as a virulence factor is completely unknown. With the aim to search for colicin production by Shigella sonnei , to evaluate the influence of culture conditions on bacteriocin ...
Tópico(s): Escherichia coli research studies
2010 - Wiley | Apmis
Produção Nacional
Revisado por pares
Patrícia Caroline Molgero Da Rós, Guilherme A.M. Silva, Adriano A. Méndes, Joana Carolina Freire Sandes Santos, Heizir F. de Castro,
The objective of this work was to produce an immobilized form of lipase from Burkholderia cepacia (lipase PS) with advantageous catalytic properties and stability to be used in the ethanolysis of different feedstocks, mainly babassu oil and tallow beef. For this purpose lipase PS was immobilized on two different non-commercial matrices, such as inorganic matrix (niobium oxide, Nb(2)O(5)) and a hybrid matrix (polysiloxane-polyvinyl alcohol, SiO(2)-PVA) by covalent binding. The properties of free and ...
Tópico(s): Electrochemical sensors and biosensors
2010 - Elsevier BV | Bioresource Technology
Produção Nacional
Revisado por pares
Moema da Silva Borges, Nayara Carolina Mendes,
Os currículos da área de saúde deixam uma lacuna na formação teórica e prática, permitindo que a morte seja interpretada como fracasso. A pesquisa objetivou apreender as representações sociais da morte e do processo de morrer para os profissionais de saúde. Trata-se de uma pesquisa qualitativa de natureza exploratória. Foram entrevistados cinco profissionais de saúde que prestam assistência a pacientes fora de possibilidades de cura. Utilizou-se o software Alceste para apreender o conteúdo das representações ...
Tópico(s): Palliative Care and End-of-Life Issues
2012 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem