Produção Nacional
Revisado por pares
Diogo Brüggemann da Conceição, Pablo Escovedo Helayel, Getúlio Rodrigues de Oliveira Filho,
... Ethics on Research Committee of the Hospital Governador Celso Ramos, 40 patients scheduled for elective hand surgeries under ... Comitê de Ética em Pesquisa do Hospital Governador Celso Ramos foram selecionados 40 pacientes escalados para operações eletivas ... Comité de Ética en Investigación del Hospital Governador Celso Ramos, se seleccionaron 40 pacientes para operaciones por elección ...
Tópico(s): Pain Management and Treatment
2009 - Elsevier BV | Brazilian Journal of Anesthesiology
Produção Nacional
Revisado por pares
Alexandre Paim Díaz, Marcelo Libório Schwarzbold, Ricardo Guarnieri, Maria Emília Rodrigues de Oliveira Thais, Alexandre Hohl, Jean Costa Nunes, Marcelo Neves Linhares, Rui Daniel Prediger, Roger Walz,
... 2008 and May 2012 at the Hospital Governador Celso Ramos, a reference center for the approximately 1 million ... the Serviço de Terapia Intensiva do Hospital Governador Celso Ramos for their kind cooperation during the study. Work ...
Tópico(s): Cardiac Arrest and Resuscitation
2014 - Wiley | CNS Neuroscience & Therapeutics
Gilma Sánchez-Burgos, Rogelio Hernández‐Pando, Iain L. Campbell, José Ramos-Castañeda, Celso Ramos,
Dengue virus encephalopathy was experimentally induced in newborn mice by i.p. inoculation of dengue 2 virus. At 6 and 9 days post-infection, motor incoordination and posterior limb paralysis were observed with focal necrosis, apoptotic cells, perivascular inflammatory cuffing and astrocytosis, mainly in the cortex and hippocampus. Expression of dengue virus genome and mRNA encoding for TNF-alpha, IL-1alpha, IL-2, IL-6, IL-1beta, IL-12 p40, IFNalpha, and IFNbeta; in addition host survival and inflammatory ...
Tópico(s): Infectious Encephalopathies and Encephalitis
2003 - Lippincott Williams & Wilkins | Neuroreport
José Luis Imbert Palafox, Patricia Guevara-Ramírez, José Ramos-Castañeda, Celso Ramos, Julio Sotelo,
Abstract Cultures of mouse brain cells containing a high proportion either neurons or astrocytes were inoculated with various strains of dengue virus. At analysis by double immunofluorescence, all strains of dengue virus studied were tropic for neurons. In no case were the astrocytes infected. Only ∼10% of all neurons were infected, suggesting that the virus may enter the cell through a membrane receptor present only in a subgroup of neurons. © 1994 Wiley‐Liss, Inc.
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
1994 - Wiley | Journal of Medical Virology
Rogelio Danis‐Lozano, Esteban E. Díaz‐González, Iliana R. Malo‐García, Mario H. Rodrı́guez, José Ramos‐Castañeda, Lilia Juárez‐Palma, Celso Ramos, Teresa López‐Ordoñez, Clemente Mosso‐González, Ildefonso Fernández‐Salas,
Abstract Background Aedes aegypti and Aedes albopictus are the main mosquito species responsible for dengue virus ( DENV ) transmission to humans in the tropical and subtropical regions of the world. The role of vertical transmission in the epidemiology of dengue and the maintenance of this arbovirus in nature during interepidemic periods remain poorly understood, and DENV vertical transmission could sustain the existence of virus reservoirs within Aedes populations. Methods Between April 2011 and October ...
Tópico(s): Viral Infections and Vectors
2019 - Wiley | Tropical Medicine & International Health
José Ramos-Castañeda, José Luis Imbert Palafox, Blanca Lilia Barrón, Celso Ramos,
Tópico(s): Viral Infections and Outbreaks Research
1997 - Springer Science+Business Media | Journal of NeuroVirology
Katrin Leitmeyer, David W. Vaughn, Douglas M. Watts, Rosalba Salas, Iris Villalobos, de Chacon, Celso Ramos, Rebeca Rico-Hesse,
ABSTRACT The understanding of dengue virus pathogenesis has been hampered by the lack of in vitro and in vivo models of disease. The study of viral factors involved in the production of severe dengue, dengue hemorrhagic fever (DHF), versus the more common dengue fever (DF), have been limited to indirect clinical and epidemiologic associations. In an effort to identify viral determinants of DHF, we have developed a method for comparing dengue type 2 genomes (reverse transcriptase PCR in six fragments) ...
Tópico(s): Malaria Research and Control
1999 - American Society for Microbiology | Journal of Virology
Produção Nacional
Revisado por pares
Érica Motta, Mavie Amaral Natalio, Pablo Tortato Waltrick,
... de pacientes com AVE, internados no Hospital Governador Celso Ramos de Florianópolis, no período de julho de 2004 ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
1999 - UNIVERSIDADE FEDERAL DE SÃO PAULO | Revista Neurociências
Celso Ramos, Gilma SÁNchez, Rogelio Hernández‐Pando, Javier Baquera, Dalia G. Hernández, Javier Mota, José Manuel Ramos, Adrian Flores, Eduardo LlausÁS,
Tópico(s): Malaria Research and Control
1998 - Springer Science+Business Media | Journal of NeuroVirology
En esta comunicación especial de la revista Salud Pública de México se hace una breve descripción de la situación de la nueva patología causada por el nuevo coronavirus a la que la OMS ha denominado Covid-19. Se hace mención de los casos ocurridos en China continental y en el resto del mundo. Del mismo modo, se enfatiza el arduo trabajo que el gobierno de China y otros países están realizando para contener la epidemia. También se hace mención del papel que están desempeñando la OMS y otras organizaciones ...
Tópico(s): COVID-19 and Mental Health
2020 - Instituto Nacional de Salud Pública | Salud Pública de México
Carlos Machaín-Williams, E. Raga, Carlos M. Baak‐Baak, Sungmin Kiem, Bradley J. Blitvich, Celso Ramos,
To increase our understanding of the consequences of dengue virus infection during pregnancy, a retrospective analysis was performed on the medical records of all completed pregnancies (live births and pregnancy losses) at nine public hospitals in the Gulf of Mexico from January to October 2013. Eighty-two patients developed clinical, laboratory-confirmed dengue virus infections while pregnant. Of these, 54 (65.9%) patients were diagnosed with dengue without warning signs, 15 (18.3%) patients were ...
Tópico(s): Viral Infections and Vectors
2018 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Ana Emília Brito, Allan O. Santos, André Deeke Sasse, César Cabello, Paulo Víctor de Oliveira, Camila Mosci, Tiago Henrique de Souza, Bárbara Juarez Amorim, Mariana Lima, Celso Darío Ramos, Elba Etchebehere,
... 1 , Barbara Amorim 1 , Mariana Lima 1, 2 , Celso D. Ramos 1, 2 , Elba Etchebehere 1, 2 1 Nuclear ...
Tópico(s): Prostate Cancer Treatment and Research
2017 - Impact Journals LLC | Oncotarget
Jorge O Pozo-Aguilar, Verónica Monroy-Martínez, Daniel Díaz, Jacqueline Barrios-Palacios, Celso Ramos, Armando Ulloa-García, Janet García-Pillado, Blanca H. Ruíz-Ordaz,
Dengue fever (DF) is the most prevalent arthropod-borne viral disease affecting humans. The World Health Organization (WHO) proposed a revised classification in 2009 to enable the more effective identification of cases of severe dengue (SD). This was designed primarily as a clinical tool, but it also enables cases of SD to be differentiated into three specific subcategories (severe vascular leakage, severe bleeding, and severe organ dysfunction). However, no study has addressed whether this classification ...
Tópico(s): Malaria Research and Control
2014 - BioMed Central | Parasites & Vectors
Juan Téllez‐Sosa, Mario H. Rodrı́guez, Rosa Elena Gómez-Barreto, Humberto Valdovinos-Torres, Ana Cecilia Hidalgo, Luis Pablo Cruz‐Hervert, René Santos Luna, Erik Carrillo-Valenzo, Celso Ramos, Lourdes García‐García, Jesús Martínez-Barnetche,
Influenza viruses display a high mutation rate and complex evolutionary patterns. Next-generation sequencing (NGS) has been widely used for qualitative and semi-quantitative assessment of genetic diversity in complex biological samples. The "deep sequencing" approach, enabled by the enormous throughput of current NGS platforms, allows the identification of rare genetic viral variants in targeted genetic regions, but is usually limited to a small number of samples.We designed a proof-of-principle study ...
Tópico(s): Bacteriophages and microbial interactions
2013 - Public Library of Science | PLoS ONE
Lucía Pérez-Álvarez, Elena Delgado, Y. Vega, Vanessa Montero, T. Cuevas, Aurora Fernández-García, B. Garcia-Riart, Sonia Pérez‐Castro, R. Rodriguez-Real, María López-Álvarez, R. Fernández-Rodríguez, María J. Lezaún, P. Ordoñez, Celso Ramos, Elena Bereciartúa, S. Calleja, Ana María Sánchez García, Michael M. Thomson,
R5-tropic viruses are associated with HIV-1 transmission and predominate during the early stages of infection. X4-tropic populations have been detected in ~50% of patients with late-stage disease infected with subtype B viruses. In this study, we compared the frequency of X4 tropism in individuals infected with HIV-1 CRF14_BG viruses, which have a V3 loop of subtype B, with a control group of individuals infected with subtype B viruses.Sixty-three individuals infected with HIV-1 CRF14_BG (n = 31) or ...
Tópico(s): Immune Cell Function and Interaction
2013 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Revisado por pares
Jean Costa Nunes, Rafael Martins, A.C. Bastos, Lucia Sukys-Claudino, Ricardo Guarnieri, Daniel de Castro Lima, Humberto Kluge Schroeder, Kátia Lin, Roger Walz,
... de Epilepsia de Santa Catarina (CEPESC), Hospital Governador Celso Ramos (HGCR), Florianopolis, Santa Catarina (SC), Brazil Servic o ...
Tópico(s): Vascular Malformations and Hemangiomas
2012 - Elsevier BV | Clinical Neurology and Neurosurgery
Alma Rosa García-Trejo, Jorge Abelardo Falcón‐Lezama, Lilia Juárez‐Palma, Julio Granados, Joaquı́n Zúñiga, Hilda Rangel, Rodrigo Barquera, Gilberto Vargas‐Alarcón, Celso Ramos,
Increased levels of tumor necrosis factor alpha (TNF-α) in patients with dengue have been reported. Various polymorphisms have been identified in the promoter region of the TNF-α gene that may affect its transcription. The purpose of the present study was to evaluate the relationship between polymorphisms of TNF-α gene and the genetic susceptibility to dengue fever in a group of patients from Morelos State, Mexico. The TNF-α polymorphisms (positions -238 and -308) were determined by PCR-RFLP technique ...
Tópico(s): Vector-borne infectious diseases
2011 - Elsevier BV | Acta Tropica
Hiroaki Kariwa, Haruka Yoshida, Cornelio Sánchez‐Hernández, Marı́a de Lourdes Romero-Almaraz, José Alberto Almazán-Catalán, Celso Ramos, Daisuke Miyashita, Takahiro Seto, Ayako Takano, Masashi Totani, Ryo Murata, Ngonda Saasa, Mariko Ishizuka, Takahiro Sanada, Kentaro Yoshii, Kumiko Yoshimatsu, Jiro Arikawa, Ikuo Takashima,
A variety of hantaviruses are harbored by rodents in North and South America, some of which can cause hantavirus pulmonary syndrome. To obtain greater evolutionary insight into hantaviruses in the Americas, a total of 211 rodents were captured in the Mexican states of Guerrero and Morelos in 2006. Anti-hantavirus antibodies were detected in 27 of 211 serum samples (12.8%) by ELISA. The distribution of seropositive rodents was: 17 Peromyscus beatae, 1 Megadontomys thomasi, 1 Neotoma picta, 6 Reithrodontomys ...
Tópico(s): Viral Infections and Outbreaks Research
2011 - Elsevier BV | Virus Research
Jorge Abelardo Falcón‐Lezama, Celso Ramos, Joaquı́n Zúñiga, Lilia Juárez‐Palma, Hilda Rangel-Flores, Alma Rosa García-Trejo, Víctor Acunha-Alonzo, Julio Granados, Gilberto Vargas‐Alarcón,
Host genetics in dengue hemorrhagic fever (DHF) pathophysiology has not been extensively investigated. Most studies have focused on HLA in different populations; however these reported associations have not been replicated. We performed a case-control study to analyze possible associations of HLA-A, HLA-B, HLA-Cw, HLA-DRB1 and HLA-DQB1 alleles with clinical disease severity caused by dengue virus infection. Our population consisted of 39 individuals (DF: 23, DHF: 16) and 34 healthy controls from the ...
Tópico(s): Vector-borne infectious diseases
2009 - Elsevier BV | Acta Tropica
María Guadalupe Ramírez-Zepeda, Héctor Eduardo Velasco-Mondragón, Celso Ramos, Javier E. Peñuelas, Marco A. Maradiaga‐Ceceña, Joel Murillo‐Llanes, Ramón Rivas-Llamas, Ricardo Chaín-Castro,
OBJETIVO: Documentar las características clínicas y epidemiológicas de los pacientes con dengue atendidos en un hospital de Culiacán, Sinaloa, México. MÉTODOS: Estudio transversal, observacional y analítico realizado en el Hospital General Dr. Bernardo J. Gastélum de Culiacán entre el 1 de octubre y el 2 de diciembre de 2003. Se evaluó la asociación entre las variables independientes (las características clínicas y epidemiológicas de los pacientes) y la variable dependiente (diagnóstico confirmado ...
Tópico(s): Vector-borne infectious diseases
2009 - Pan American Health Organization | Revista Panamericana de Salud Pública
Diogo Brüggemann da Conceição, Pablo Escovedo Helayel, Getúlio Rodrigues de Oliveira Filho,
... Comitê de Ética em Pesquisa do Hospital Governador Celso Ramos foram selecionados 40 pacientes escalados para operações eletivas ...
Tópico(s): Pain Management and Treatment
2009 - Elsevier BV | Brazilian Journal of Anesthesiology
M Hidalgo-Martínez, Fernando I. Puerto, José A. Farfán-Ale, Julián E. García‐Rejón, Elsy del P Rosado-Paredes, Jorge F. Méndez-Galván, Raymunda Figueroa-Ocampo, Ikuo Takashima, Celso Ramos,
OBJETIVO: Determinar la prevalencia de infección por el virus del Nilo Occidental (VNO) en animales, mosquitos y personal que labora en dos zoológicos del estado de Tabasco, en México. MATERIAL Y MÉTODOS: Con la utilización de ELISA de bloqueo se detectaron anticuerpos en sueros de animales: se buscó un fragmento del genoma del VNO por RT-PCR en el suero de animales, empleados y mosquitos. RESULTADOS: En el zoológico "La Venta" se encontró una seroprevalencia de 25.67% (19/74) en aves y de 85.71% (6/ ...
Tópico(s): Malaria Research and Control
2008 - Instituto Nacional de Salud Pública | Salud Pública de México
Álvaro Aguilar‐Setién, M. L. ROMERO-ALMARAZ, Cornelio Sánchez‐Hernández, Raymunda Figueroa, Lilia Juárez‐Palma, María Martha García-Flores, Carlos Vázquez-Salinas, Mónica Salas-Rojas, Ana C Hidalgo-Martínez, Sebastián Pierlé, Carlos García-Estrada, Celso Ramos,
SUMMARY Individuals belonging to five families, 12 genera, and 19 different species of bats from dengue endemic areas in the Gulf and Pacific coasts of Mexico were examined by ELISA, RT–PCR, and for the presence of dengue virus (DV) NS1 protein. Nine individuals from four species were seropositive by ELISA: three insectivorous, Myotis nigricans (four positives/12 examined), Pteronotus parnellii (3/19), and Natalus stramineus (1/4), and one frugivorous Artibeus jamaicensis (1/35) (12·86% seroprevalence ...
Tópico(s): Virology and Viral Diseases
2008 - Cambridge University Press | Epidemiology and Infection
Javier Mota, Maribel Acosta, Rocio Argotte, Raymunda Figueroa, Armando J. Mendez, Celso Ramos,
Dengue fever is a growing public health concern around the world and despite vaccine development efforts, there are currently no effective dengue vaccines. In the present study we report the induction of protective antibodies against dengue virus by DNA immunization with domain III (DIII) region of the envelope protein (E) in a mouse model. The DIII region of all four dengue virus serotypes were cloned separately into pcDNA 3 plasmid. Protein expression was tested in COS-7 cells. Each plasmid, or ...
Tópico(s): Malaria Research and Control
2005 - Elsevier BV | Vaccine
Curtis Lafleur, Julio Granados, Gilberto Vargas‐Alarcón, Jorge A Ruiz-Morales, Cynthia Villarreal‐Garza, Lorena Higuera, Guadalupe Hernández‐Pacheco, Teresa Cutiño‐Moguel, Hilda Rangel, Raymunda Figueroa, Maribel Acosta, Eduardo Lazcano, Celso Ramos,
The human leukocyte antigen DRB1 locus (HLA-DRB1) was typed in genomic DNA extracted from whole blood samples of 34 Mexican dengue hemorrhagic fever (DHF) patients and 47 dengue fever (DF) patients, by polymerase chain reaction-sequence-specific oligonucleotide reverse dot blot. HLA-DRB1*04 was negatively associated with risk of DHF (OR 0.31, 95% CI 0.11-0.85). HLA-DR4 homozygous individuals were 11.6 times less likely to develop DHF in comparison to DR4 negative persons (OR 0.08, 95% CI 0.01-0.75). ...
Tópico(s): Viral Infections and Outbreaks Research
2002 - Elsevier BV | Human Immunology
Hilda Rangel-Flores, Beatriz Rivas Sánchez, J Mendoza-Duarte, Christian Barnabé, Simone Frédérique Brénière, Celso Ramos, Bertha Espinoza,
Trypanosoma cruzi infection in central Mexico has not been fully documented, yet some data suggest its presence. In this work, sera from 211 subjects living in the state of Morelos and at risk of T. cruzi infection due to their living in contact with the vector were analyzed for the presence of antibodies to a total antigen extract of a Mexican isolate of T. cruzi. A seropositivity of 20% was demonstrated by both an enzyme-linked immunosorbent assay and Western blotting. Furthermore, parasites were ...
Tópico(s): Trypanosoma species research and implications
2001 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Raymunda Figueroa, Celso Ramos,
Tópico(s): Malaria Research and Control
2000 - Elsevier BV | Archives of Medical Research
Produção Nacional
Revisado por pares
Andrea Ferrari, Paulo R. P. Hofmann,
... fishes are cultivated, in the city of Governador Celso Ramos, also in Santa Catarina State. The occurrence in ...
Tópico(s): Phytochemistry and Bioactivity Studies
1992 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo
Celso Ramos, Ilse Schädtler-Siwon, L Ortíz-Ortíz,
Infection with Trypanosoma cruzi decreases the ability of spleen cells from mice to respond to either T cell, concanavalin A (Con A), or B cell, lipopolysaccharide (LPS), mitogens. The effect of infection on the mitogenic response depends on the elapsed time between the day of infection and the time of mitogen presentation. Responses early in infection are normal, whereas later responses to either mitogen are depressed. Spleen cells from late trypanosome-infected mice inhibit the ability of normal ...
Tópico(s): Parasites and Host Interactions
1979 - American Association of Immunologists | The Journal of Immunology
Celso Ramos, Edmundo Lamoyi, Miguel Feoli, Miguel Á. Rodríguez, M.F. Correa Perez, L Ortíz-Ortíz,
Trypanosoma cruzi: Immunosuppressed response to different antigens in the infected mouse. Experimental Parasitology45, 190–199. Trypanosoma cruzi infection in mice results in functional changes in the normal immunological responses to heterologous antigens. An immunosuppression of the 19 and 7S antibody response is observed in infected animals against both a particulate antigen and against soluble antigens. Furthermore, the immune response to the soluble T-independent antigens, DNP-Ficoll and LPS, ...
Tópico(s): Parasitic Infections and Diagnostics
1978 - Elsevier BV | Experimental Parasitology