... S.-P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ... S.-P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ... S.-P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ... S.-P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ... S.-P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ... S.-P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ...
Tópico(s): Bacterial biofilms and quorum sensing
2009 - Cell Press | Cell Host & Microbe
... S.P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ... S.P. Paixao T.A. Butler B.P. Chu H. Santos R.L. Berger T. et al.Cell Host ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2014 - Cell Press | Immunity
Manuela Raffatellu, Michael D. George, Yuko Akiyama, Michael Hornsby, Sean‐Paul Nuccio, Tatiane A. Paíxão, Brian P. Butler, Hiutung Chu, Renato L. Santos, Thorsten Berger, Tak W. Mak, Renée M. Tsolis, Charles Bevins, Jay V. Solnick, Satya Dandekar, Andreas J. Bäumler,
In response to enteric pathogens, the inflamed intestine produces antimicrobial proteins, a process mediated by the cytokines IL-17 and IL-22. Salmonella enterica serotype Typhimurium thrives in the inflamed intestinal environment, suggesting that the pathogen is resistant to antimicrobials it encounters in the intestinal lumen. However, the identity of these antimicrobials and corresponding bacterial resistance mechanisms remain unknown. Here, we report that enteric infection of rhesus macaques ...
Tópico(s): Clinical Nutrition and Gastroenterology
2009 - Cell Press | Cell Host & Microbe
Moupali Das, Priscilla Lee Chu, Glenn‐Milo Santos, Susan Scheer, Eric Vittinghoff, Willi McFarland, Grant Colfax,
At the individual level, higher HIV viral load predicts sexual transmission risk. We evaluated San Francisco's community viral load (CVL) as a population level marker of HIV transmission risk. We hypothesized that the decrease in CVL in San Francisco from 2004-2008, corresponding with increased rates of HIV testing, antiretroviral therapy (ART) coverage and effectiveness, and population-level virologic suppression, would be associated with a reduction in new HIV infections.We used San Francisco's ...
Tópico(s): Sex work and related issues
2010 - Public Library of Science | PLoS ONE
Patrizia Paradiso, V. Chu, Luís F. Santos, Ana Paula Serro, R. Colaço, Benilde Saramago,
Abstract Although the plasma technology has long been applied to treat contact lenses, the effect of this treatment on the performance of drug‐loaded contact lenses is still unclear. The objective of this work is to study the effect of nitrogen plasma treatment on two drug‐loaded polymeric formulations which previously demonstrated to be suitable for therapeutic contact lenses: a poly‐hydroxyethylmethacrylate (pHEMA) based hydrogel loaded with levofloxacin and a silicone‐based hydrogel loaded with ...
Tópico(s): Liquid Crystal Research Advancements
2014 - Wiley | Journal of Biomedical Materials Research Part B Applied Biomaterials
Moupali Das, Paul A. Volberding,
... 493-505. [PMID: 21767103] CrossrefMedlineGoogle Scholar7. Das M, Chu PL, Santos GM, Scheer S, Vittinghoff E, McFarland W, et ...
Tópico(s): HIV-related health complications and treatments
2013 - American College of Physicians | Annals of Internal Medicine
Produção Nacional
Revisado por pares
Tee Wei Siah, Hongwei Guo, Thomas Chu, Leopoldo Duailibe Nogueira Santos, Hisae Nakamura, Gigi Leung, Jerry Shapiro, Kevin J. McElwee,
Platelet-rich plasma (PRP), processed from autologous peripheral blood, is used to treat androgenetic alopecia (AGA).To determine the efficacy of PRP for hair growth promotion in AGA patients in a randomized, blinded, placebo-controlled, pilot clinical trial (NCT02074943).The efficacy of an 8 week, five session, PRP treatment course was determined by measuring hair density and hair caliber changes in 10 AGA affected patients. For each PRP sample, the concentrations of selected growth factors were determined ...
Tópico(s): Periodontal Regeneration and Treatments
2020 - Wiley | Experimental Dermatology
Heather A. Parsons, Timothy Blewett, Xun Chu, Sainetra Sridhar, Katheryn Santos, Kan Xiong, Vandana G. Abramson, Ayan R. Patel, Justin Cheng, Adam Brufsky, Justin Rhoades, Jeremy Force, Rong Liu, Tiffany A. Traina, Lisa A. Carey, Mothaffar F. Rimawi, Kathy D. Miller, Vered Stearns, Jennifer M. Specht, Carla I. Falkson, Harold J. Burstein, Antonio C. Wolff, Eric P. Winer, Nabihah Tayob, Ian E. Krop, G. Mike Makrigiorgos, Todd R. Golub, Erica L. Mayer, Viktor A. Adalsteinsson,
We aimed to examine circulating tumor DNA (ctDNA) and its association with residual cancer burden (RCB) using an ultrasensitive assay in patients with triple-negative breast cancer (TNBC) receiving neoadjuvant chemotherapy.
Tópico(s): Genetic factors in colorectal cancer
2023 - Elsevier BV | Annals of Oncology
... 921-9. [PMID: 10738050] CrossrefMedlineGoogle Scholar13. Das M, Chu PL, Santos GM, Scheer S, Vittinghoff E, McFarland W, et ...
Tópico(s): HIV Research and Treatment
2011 - American College of Physicians | Annals of Internal Medicine
Sara Gianella, Richard Haubrich, Sheldon Morris,
... 2098 (2010).Crossref, Medline, Google Scholar4 Das M, Chu PL, Santos GM et al. Decreases in community viral load ...
Tópico(s): HIV, Drug Use, Sexual Risk
2013 - Future Medicine | Future Virology
Produção Nacional
Revisado por pares
Leandro dos Santos Coelho, Chu-Sheng Lee,
The objective of the Economic Dispatch Problems (EDPs) of electric power generation is to schedule the committed generating units outputs so as to meet the required load demand at minimum operating cost while satisfying all units and system equality and inequality constraints. Recently, global optimization approaches inspired by swarm intelligence and evolutionary computation approaches have proven to be a potential alternative for the optimization of difficult EDPs. Particle swarm optimization (PSO) ...
Tópico(s): Optimal Power Flow Distribution
2007 - Elsevier BV | International Journal of Electrical Power & Energy Systems
Produção Nacional
Revisado por pares
Naíla Cannes do Nascimento, Andrea Pires dos Santos, Yuefeng Chu, Ana M. S. Guimarães, A. N. Baird, Ann B. Weil, Joanne B. Messick,
Mycoplasma parvum [Eperythrozoon parvum] is the second hemotrophic mycoplasma (hemoplasma) described in pigs. Unlike M. suis, its closest phylogenetic relative, M. parvum, is considered a non-pathogenic bacterium in this host species. Natural infection of a domestic, 6-month-old splenectomized pig with M. parvum strain Indiana is described herein. Light and scanning electron microscopy of the bacteria were performed in addition to whole genome sequencing, analysis, and comparison to the genome of ...
Tópico(s): Viral Infections and Vectors
2014 - BioMed Central | Veterinary Research
C. K. Xu, Chen Cao, N. Lu, Yu Gao, P. van der Werf, A. Evans, J. M. Mazzarella, J. Chu, S. Haan, T. Díaz-Santos, R. Meijerink, Yinghe Zhao, P. N. Appleton, L. Armus, V. Charmandaris, S. Lord, E. J. Murphy, D. B. Sanders, B. Schulz, S. Stierwalt,
We present ALMA Cycle-0 observations of the CO (6-5) line emission (rest-frame frequency = 691.473 GHz) and of the 435$\mu m$ dust continuum emission in the nuclear region of NGC 34, a local luminous infrared galaxy (LIRG) at a distance of 84 Mpc (1" = 407 pc) which contains a Seyfert 2 active galactic nucleus (AGN) and a nuclear starburst. The CO emission is well resolved by the ALMA beam ($\rm 0."26\times 0."23$), with an integrated flux of $\rm f_{CO~(6-5)} = 1004\; (\pm 151) \; Jy\; km\; s^{-1}$. Both the morphology ...
Tópico(s): Astrophysical Phenomena and Observations
2014 - IOP Publishing | The Astrophysical Journal
Ruben R. G. Soares, D. Roda Dos Santos, V. Chu, Ana M. Azevedo, M. Raquel Aires‐Barros, J. P. Conde,
For a point-of-use analytical device to be successful in real-world applications, it needs to be rapid, simple to operate and, ideally, able to multiplex the detection of several analytes and samples. Mycotoxin detection in food and feedstock in particular has become increasingly relevant as these toxins, such as ochratoxin A (OTA), aflatoxin B1 (AFB1) and deoxynivalenol (DON), are subject to strict regulations and recommendations in the European Union. A novel, simple, negative pressure-driven device ...
Tópico(s): Listeria monocytogenes in Food Safety
2016 - Elsevier BV | Biosensors and Bioelectronics
Produção Nacional
Revisado por pares
Naíla Cannes do Nascimento, Ana M. S. Guimarães, Andrea Pires dos Santos, Yuefeng Chu, Lucas Miranda Marques, Joanne B. Messick,
Pigs are popular animal models in biomedical research. RNA-Seq is becoming the predominant tool to investigate transcriptional changes of the pig's response to infection. The high sensitivity of this tool requires a strict control of the study design beginning with the selection of healthy animals to provide accurate interpretation of research data. Pigs chronically infected with Mycoplasma suis often show no obvious clinical signs, however the infection may affect the validity of animal research. ...
Tópico(s): Immune Response and Inflammation
2018 - BioMed Central | Veterinary Research
Ruben R. G. Soares, Felix Neumann, Catarina R.F. Caneira, Narayanan Madaboosi, Sibel Ciftci, Iván Hernández-Neuta, Inês F. Pinto, D. Roda Dos Santos, V. Chu, Aman Russom, J. P. Conde, Mats Nilsson,
The rapid and sensitive detection of specific nucleic acid sequences at the point-of-care (PoC) is becoming increasingly in demand for a variety of emergent biomedical applications ranging from infectious disease diagnostics to the screening of antimicrobial resistance. To meet such demand, considerable efforts have been invested towards the development of portable and integrated analytical devices combining microfluidics with miniaturized signal transducers. Here, we demonstrate the combination ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2018 - Elsevier BV | Biosensors and Bioelectronics
... May-2010.Liss M, Osann K, Canvasser N, Chu W, Chang A, Gan J, Li R, Santos R, Skarecky D, Finley D and Ahlering T ( ...
Tópico(s): Pelvic floor disorders treatments
2004 - Lippincott Williams & Wilkins | The Journal of Urology
John T. Wei, Rodney L. Dunn, Robert Marcovich, James E. Montie, Martin G. Sanda,
... Sep-2010.Liss M, Osann K, Canvasser N, Chu W, Chang A, Gan J, Li R, Santos R, Skarecky D, Finley D and Ahlering T ( ...
Tópico(s): Pelvic floor disorders treatments
2000 - Lippincott Williams & Wilkins | The Journal of Urology
Produção Nacional
Revisado por pares
David J. Bertioli, Peggy Ozias‐Akins, Ye Chu, Karinne M Dantas, Silvio P. Santos, Ediene G Gouvea, P. M. Guimarães, Soraya C. M. Leal‐Bertioli, Steven J. Knapp, Márcio de Carvalho Moretzsohn,
Abstract Single nucleotide polymorphic markers (SNPs) are attractive for use in genetic mapping and marker-assisted breeding because they can be scored in parallel assays at favorable costs. However, scoring SNP markers in polyploid plants like the peanut is problematic because of interfering signal generated from the DNA bases that are homeologous to those being assayed. The present study used a previously constructed 1536 GoldenGate SNP assay developed using SNPs identified between two A. duranensis ...
Tópico(s): Agricultural pest management studies
2013 - Genetics Society of America | G3 Genes Genomes Genetics
Produção Nacional
Revisado por pares
Woo Ho Kim, Lourdes Gómez Izquierdo, F Vilardell, Kent‐Man Chu, Geneviève Soucy, Lucas Vieira dos Santos, Geneviève Monges, Giuseppe Viale, María José Brito, Stuart Osborne, Johannes Noé, Xiang Du,
Human epidermal growth factor receptor 2 (HER2) dysregulation is associated with tumorigenesis in gastric/gastroesophageal junction cancer; however, the number of patients with HER2-positive disease is unclear, possibly due to differing scoring criteria/assays. Data are also lacking for early disease. We aimed to assess the HER2-positivity rate using approved testing criteria in a large, real-life multinational population. HER2-positivity was defined as an immunohistochemistry staining score of 3+, ...
Tópico(s): Colorectal Cancer Treatments and Studies
2016 - Lippincott Williams & Wilkins | Applied immunohistochemistry & molecular morphology
William J. Catàlona, Gustavo Franco Carvalhal, DOUGLAS E. MAGER, Deborah S. Smith,
... Mar-2010.Liss M, Osann K, Canvasser N, Chu W, Chang A, Gan J, Li R, Santos R, Skarecky D, Finley D and Ahlering T ( ...
Tópico(s): Advanced Radiotherapy Techniques
1999 - Lippincott Williams & Wilkins | The Journal of Urology
Thomas Chu, Leopoldo Duailibe Nogueira Santos, Kevin J. McElwee,
There are many hair disorders, all of which involve alterations in normal hair biology. Essentially, hair disorders involve changes to hair fiber caliber, density per unit area, and/or the duration of anagen and telogen in the hair growth cycle. Hair disorders may be triggered by inflammation, genetics, the environment, or hormones; the relative contributions of these factors vary for different hair disorder diagnoses. Suitable treatments may either address the underlying causal factors or directly ...
Tópico(s): Cancer and Skin Lesions
2015 - | Seminars in Cutaneous Medicine and Surgery
Produção Nacional
Revisado por pares
Elis Janaína Lira dos Santos, Amanda Bandeira de Almeida, M.B. Chavez, Cristiane R. Salmon, Luciana Souto Mofatto, Mariana Barbosa Câmara‐Souza, Michelle H. Tan, Tamara N. Kolli, Fatma F. Mohamed, Emily Y. Chu, Pedro Duarte Novaes, Eduardo C A Santos, Kamila Rosamilia Kantovitz, Brian L. Foster, Francisco Humberto Nociti,
Cementum is a mineralized tissue that covers tooth roots and functions in the periodontal attachment complex. Cementocytes, resident cells of cellular cementum, share many characteristics with osteocytes, are mechanoresponsive cells that direct bone remodeling based on changes in loading. We hypothesized that cementocytes play a key role during orthodontic tooth movement (OTM). To test this hypothesis, we used 8-week-old male Wistar rats in a model of OTM for 2, 7, or 14 days (0.5 N), whereas unloaded ...
Tópico(s): Proteoglycans and glycosaminoglycans research
2021 - Elsevier BV | Bone
Cláudio Luís Santos Sampaio, Show-Chu Wong, Elliott Shaw,
A method is described for the convenient purification of the protease plasma kallikrein from human Cohn fraction IV-1. The enzyme was produced by endogenous activation after acid treatment to remove an inhibitor and was concentrated by the successive use of affinity adsorbents prepared by the immobilization of soybean trypsin inhibitor and aminobenzamidine. The esterase- and kinin-producing activities were enriched about 1100-fold from fraction IV-1. Several properties of plasma kallikrein strengthen ...
Tópico(s): Molecular Junctions and Nanostructures
1974 - Elsevier BV | Archives of Biochemistry and Biophysics
Silvia Santos, Kengyeh K. Chu, Daryl Lim, Nenad Bozinovic, Timothy N. Ford, Claire Hourtoule, Aaron C. Bartoo, Satish K. Singh, Jérôme Mertz,
We present an endomicroscope apparatus that exhibits out-of-focus background rejection based on wide-field illumination through a flexible imaging fiber bundle. Our technique, called HiLo microscopy, involves acquiring two images, one with grid-pattern illumination and another with standard uniform illumination. An evaluation of the image contrast with grid-pattern illumination provides an optically sectioned image with low resolution. This is complemented with high-resolution information from the ...
Tópico(s): Advanced Fluorescence Microscopy Techniques
2009 - SPIE | Journal of Biomedical Optics
Moupali Das, Deirdre Santos, Tim Matheson, Glenn‐Milo Santos, Priscilla Lee Chu, Eric Vittinghoff, Steven Shoptaw, Grant Colfax,
Objective: To determine whether actively using, methamphetamine (meth)-dependent men who have sex with men (MSM) could be enrolled and retained in a pharmacologic intervention trial, and the degree to which participants would adhere to study procedures, including medication adherence. Study design: Phase II randomized, double-blind trial of bupropion vs. placebo. Methods: Thirty meth-dependent, sexually active MSM were randomized to receive daily bupropion XL 300 mg or placebo for 12 weeks. Participants ...
Tópico(s): Substance Abuse Treatment and Outcomes
2010 - Lippincott Williams & Wilkins | AIDS
Grant Colfax, Glenn‐Milo Santos, Priscilla Lee Chu, Eric Vittinghoff, Andreas Plüddemann, Suresh Kumar, Carl L. Hart,
Summary Amphetamine-group substances are used worldwide and are more prevalent than either cocaine or opioids. We reviewed published reports about amphetamine-group substances and did a meta-analysis of randomised controlled trials of behavioural interventions for their use. Most research was done in developed countries. Many, but not all, studies show an association between amphetamine-group substance use and risk of HIV infection. Much use of amphetamine-group substances is non-injection and is associated ...
Tópico(s): Cannabis and Cannabinoid Research
2010 - Elsevier BV | The Lancet
J.E. Bourée, T. Heitz, C. Godet, B. Drévillon, J. P. Conde, V. Chu, Mário N. Berberan‐Santos, А.А. Федоров,
The visible photoluminescence (PL) properties (emission and excitation spectra) of hydrogenated amorphous carbon (a-C:H) have been investigated for polymer-like thin films grown at low substrate temperature and small ion energies. For a large number of a-C:H films grown in three reactors (dual-mode plasma, radio frequency plasma and electron cyclotron resonance plasma) the emission spectra appear as a sum of three peaks with energies (a) 2.28 eV, (b) 2.65 eV and (c) 2.95 eV, being independent of the excitation ...
Tópico(s): Semiconductor materials and devices
1998 - Elsevier BV | Journal of Non-Crystalline Solids
Produção Nacional
Revisado por pares
Hegel Trujillo-Santamaría, José Iván Robles-Torres, Jeremy Yuen‐Chun Teoh, Yılören Tanıdır, J.G. Campos-Salcedo, Edgar Iván Bravo-Castro, Marcelo Langer Wroclawski, Wei Sien Yeoh, Santosh Kumar, Juan Eduardo Sánchez-Núñez, José Enrique Espinoza-Aznar, Deepak Ragoori, Saeed Bin Hamri, Teng Aik Ong, Cecil Paul Tarot-Chocooj, Anil Shrestha, Mohamed Amine Lakmichi, Mateus Cosentino-Bellote, Luis Gabriel Vázquez‐Lavista, Boukary Kabré, Ho Yee Tiong, José Gustavo Arrambide-Herrera, Lauro Salvador Gómez-Guerra, Umut Kutukoglu, Joao Arthur Brunhara Alves-Barbosa, Jorge Jaspersen, Christian Acevedo, Francisco Virgen-Gutiérrez, Sumit Agrawal, Hugo Octaviano Duarte-Santos, Chu Ann Chai, Daniele Castellani, Vineet Gahuar,
Emphysematous pyelonephritis (EPN) is a necrotizing infection of the kidney and the surrounding tissues associated with considerable mortality. We aimed to formulate a score that classifies the risk of mortality in patients with EPN at hospital admission.
Tópico(s): Kidney Stones and Urolithiasis Treatments
2022 - Lippincott Williams & Wilkins | Current Urology
Tsen‐Fang Tsai, Murlidhar Rajagopalan, Chia‐Yu Chu, Lonabel Encarnacion, Robert A. Gerber, Paul Santos‐Estrella, Lyndon Llamado, Anna M. Tallman,
Atopic dermatitis is a chronic, inflammatory skin disease characterized by intense pruritus and eczematous lesions. It is considered one of the most common chronic conditions, with an estimated global prevalence of nearly 230 million. As in the rest of the world, prevalence of atopic dermatitis has been increasing in Asian countries over the last few decades. This increased prevalence in Asian countries has been attributed to factors such as rapid urbanization, increasingly Westernized lifestyles, ...
Tópico(s): Food Allergy and Anaphylaxis Research
2019 - Wiley | The Journal of Dermatology