Yu‐Jing Jin, Cha-Chi Lin, Tzy‐Ming Lu, Jih‐Heng Li, Ih‐Sheng Chen, Yueh‐Hsiung Kuo, Horng‐Huey Ko,
Twenty-four compounds, including the previously unknown artoxanthocarpuone A, artoxanthocarpuone B, hydroxylakoochin A, methoxylakoochin A, epoxylakoochin A, and artoxanthol, were isolated and characterized spectroscopically. Among them, artoxanthol is stilbene oligomer presumably constructed in a 5,11,12-triphenyl hexahydrochrysene scaffold by a Diels–Alder type of reaction, for which a biosynthetic pathway is proposed. Artoxanthol, alboctalol, steppogenin, norartocarpetin, resveratrol, oxyresveratrol, ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2015 - Elsevier BV | Phytochemistry
Yi‐Shuan Sheen, Yi‐Hua Liao, Ming‐Hsien Lin, Chia‐Ying Chu, Bing‐Ying Ho, Meng-Chen Hsieh, Pin‐Chun Chen, Shih-Ting Cha, Yung‐Ming Jeng, Cheng-Chi Chang, Hsien‐Ching Chiu, Shiou‐Hwa Jee, Min‐Liang Kuo, Chia‐Yu Chu,
IGF II mRNA-binding protein 3 (IMP-3) has been reported to be a marker of melanoma progression. However, the mechanisms by which it impacts melanoma are incompletely understood. In this study, we investigate the clinical significance of IMP-3 in melanoma progression and also its underlying mechanisms. We found that IMP-3 expression was much higher in advanced-stage/metastatic melanomas and that it was associated with a poor prognosis (P=0.001). Univariate analysis showed that IMP-3 expression was ...
Tópico(s): interferon and immune responses
2014 - Elsevier BV | Journal of Investigative Dermatology
Tzong-Hsien Lee, Dar‐In Tai, Cha-Ju Cheng, Chi-Shu Sun, Ching-Yih Lin, Ming-Jen Sheu, Wei-Ping Lee, Cheng‐Yuan Peng, Andrew H.‐J. Wang, Sun-Lung Tsai,
Chronic infections with hepatitis B and C viruses (HBV and HCV) are etiologically linked to hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). Both viruses may induce activation of nuclear factor-kappa B (NF-κB) in hepatocytes that plays a crucial role in the regulation of cell growth and apoptosis. Functional proteomics analysis of proteins associated with NF-κB signaling complexes in both viruses-related HCC tumor and non-tumor tissues may disclose possible common mechanisms in hepatocarcinogenesis. ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2005 - BioMed Central | Journal of Biomedical Science
Chien‐Chang Kao, Yi‐Ching Cheng, Ming‐Hsin Yang, Tai‐Lung Cha, Guang‐Huan Sun, Chi‐Tang Ho, Yingchao Lin, Hao‐Kuang Wang, Sheng‐Tang Wu, Tzong‐Der Way,
Bladder cancer is the most common malignancy of the urinary tract and arising from the epithelial lining of the urinary bladder. Resistance to cytotoxic therapies is associated with overexpression of oncogenic proteins; including HER2, and Akt in chemotherapy resistance of bladder cancer. Various studies demonstrated that curcuminoids, the most important active phenolic compounds of turmeric (Curcuma longa), have anti-tumor activities in a wide range of human malignant cell lines. The aim of this ...
Tópico(s): Heat shock proteins research
2021 - Wiley | Environmental Toxicology
Jui‐Chin Chen, John H. Lau, Pei-Jer Tzeng, Shang-Chun Chen, Chien-Ying Wu, Chien Chou Chen, Yu Chen Hsin, Y. Y. Hsu, Shang Hung Shen, Sue-Chen Liao, Chi‐Hon Ho, Cha-Hsin Lin, Tzu-Kun Ku, Ming‐Jer Kao,
In this paper, the optimization of Cu chemical-mechanical polishing (CMP) performance (dishing) for the removal of thick Cu-plating overburden due to Cu plating for deep through silicon via (TSV) in a 300-mm wafer is investigated. Moreover, backside isolation oxide CMP for TSV Cu exposure is examined. To obtain a minimum Cu dishing on the TSV region, a proper selection of Cu slurries is proposed for the current two-step Cu-polishing process. First, a bulk of Cu is removed with the slurry of high Cu ...
Tópico(s): Integrated Circuits and Semiconductor Failure Analysis
2012 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Components Packaging and Manufacturing Technology
Chi‐Jen Chang, Ming‐Lun Yeh, Cha-Chun Chen,
Tópico(s): Chromatin Remodeling and Cancer
2007 - Springer Science+Business Media | Pediatric Surgery International
Chuang-Chi Liaw, Jen-Sheng Huang, Hung-Ming Wang, Cha-Hsiu Wang,
Background. Spontaneous gastroduodenal perforation is an uncommon but life-threatening complication of systemic chemotherapy and/or steroids. Here, the authors reported four cases of gastroduodenal perforation following combined chemotherapy with steroids. Methods. The chemotherapeutic regimens all included 5-fluorouracil (5-FU) by continuous infusion and cisplatin. The authors used dexamethasone as an antiemetic. All patients took analgesics for pain relief. No patient had a history of peptic ulcer ...
Tópico(s): Mycobacterium research and diagnosis
1993 - Wiley | Cancer
Tzong‐Yow Tsai, Zhi‐Cheng Lee, J.C. Chen, Chi‐Chung Chen, Yen-Cheng Fang, Ming‐Hong Cha,
A novel ultracompact 2/spl times/2 wavelength division multiplexer (WDM) for 1.55-/spl mu/m operation based on highly dispersive two-mode interference (TMI) was designed, theoretically modeled, and verified using a finite-difference-time-domain (FDTD) method. A two-moded waveguide assisted with a dispersive tooth-shaped grating provided a mode-dependent reflection band of central wavelength at 1.55 /spl mu/m. The wavelengths of 1538 and 1572 nm that were at the band edges and had the lowest reflection ...
Tópico(s): Advanced Photonic Communication Systems
2005 - IEEE Photonics Society | IEEE Journal of Quantum Electronics
Shih-Ting Cha, Ching‐Ting Tan, Cheng‐Chi Chang, Chia‐Yu Chu, Wei-Jiunn Lee, Been-Zen Lin, Ming‐Tsan Lin, Min‐Liang Kuo,
Tópico(s): Histone Deacetylase Inhibitors Research
2016 - Nature Portfolio | Nature Cell Biology
Yu‐Sheng Lin, Yung‐Lung Chen, Tien‐Hsing Chen, Ming‐Shyan Lin, Chi‐Hung Liu, Teng‐Yao Yang, Chang-Ming Chung, Mien‐Cheng Chen,
Importance Current guidelines support treating atrial fibrillation (AF) and atrial flutter (AFL) as equivalent risk factors for ischemic stroke stratified by CHA 2 DS 2 -VASc scores, recommending anticoagulation therapy for patients with a CHA 2 DS 2 -VASc score of 2 or higher, but some studies found differences in clinical outcomes. Objective To investigate differences in clinical outcomes among AF, AFL, and matched control cohorts. Design, Setting, and Participants This nationwide cohort study analyzed data ...
Tópico(s): Acute Ischemic Stroke Management
2018 - American Medical Association | JAMA Network Open
Wei-Chiung Chi, Weiling Chen, Chih-Chiao He, Sheng−Yu Guo, Hyo-Jung Cha, Ling Ming Tsang, Tsz Wai Ho, Ka‐Lai Pang,
A high diversity of culturable foliar endophytic fungi is known from various mangrove plants, and the core taxa include species from Colletotrichum , Pestalotiopsis , Phoma , Phomopsis , Sporomiella , among others. Since a small fraction of fungi is able to grow in culture, this study investigated the diversity of fungi associated with leaves of Acanthus ilicifolius var. xiamenensis using both isolation and metabarcoding approaches. A total of 203 isolates were cultured from surface-sterilized leaves, representing ...
Tópico(s): Plant-Microbe Interactions and Immunity
2019 - PeerJ, Inc. | PeerJ
Rolf Teschke, Li Zhang, Hong-Zhu Long, Alexander Schwarzenboeck, Wolfgang Schmidt‐Taenzer, A Genthner, Albrecht Wolff, Christian Frenzel, Johannes Schulze, Axel Eickhoff,
... Cao, Ji Xue Cao, Jin Bu Huan, Jue Ming Zi, Jiguja, Kudzu, Ling Yang Qing Fei Keli, Lu Cha, Rhen Shen, Ma Huang, Shou Wu Pian, Shan Chi, Shen Min, Syo Saiko To, Xiao Chai Hu ...
Tópico(s): Nephrotoxicity and Medicinal Plants
2015 - Elsevier BV | Annals of Hepatology
Rolf Teschke, Li Zhang, Hoàng Vĩnh Long, Alexander Schwarzenboeck, Wolfgang Schmidt‐Taenzer, A Genthner, A. Wolff, Christian Frenzel, Johannes Schulze, A Eickhoff, Axel Wiebrecht,
... Cao, Ji Xue Cao, Jin Bu Huan, Jue Ming Zi, Jiguja, Kudzu, Ling Yang Qing Fei Keli, Lu Cha, Rhen Shen, Ma Huang, Shou Wu Pian, Shan Chi, Shen Min, Syo Saiko To, Xiao Chai Hu ...
Tópico(s): Poisoning and overdose treatments
2016 - Springer Science+Business Media | Deutsche Zeitschrift für Akupunktur
Huei‐Chi Chou, Chien‐Hung Chen, Mei–Hsuan Lee, Cha‐Ze Lee, Guan‐Tarn Huang, Pei‐Ming Yang, Po–Huang Lee, Jin‐Chuan Sheu,
To evaluate whether the tumour suppressor gene, PPP2R1B, is involved in pathogenesis of hepatocellular carcinoma (HCC), reverse transcription-polymerase chain reaction (RT-PCR) and cDNA sequencing were performed. Eleven of 38 (29%) tumours and 1 of 34 (3%) corresponding non-tumour tissues showed coexpression of wild-type and aberrant mRNA. Various deletions were found in aberrant transcripts. Southern blot analysis did not show gene deletion in tumours, suggesting abnormal RNA splicing may be involved. ...
Tópico(s): Cancer Genomics and Diagnostics
2007 - Elsevier BV | Cancer Letters
Chi‐Ling Hang, Cha-Ping Wang, Hon‐Kan Yip, Cheng‐Hsu Yang, G. Bih-Fang Guo, Chiung‐Jen Wu, Shyh‐Ming Chen,
Background Intracoronary calcium-channel blockers administered in the event of no reflow during percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) have been shown to improve myocardial perfusion. Study objective To evaluate the effects of the administration of intracoronary verapamil before the occurrence of no reflow during direct PCI. Design and setting Single-center, nonrandomized, prospective study with a retrospective control group. Patients and methods From September ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2005 - Elsevier BV | CHEST Journal
... Ji Xue Cao, Jiguja, Jin Bu Huan, Jue Ming Zi, Kamishoyosan, Kudzu, Lei Gong Teng, Long Dan Xie Gan Tang, Lu Cha, Ma Huang, Mao Guo Tian Jie Cai, Onshido, Polygonum multiflorum, Qian Li Guang, Ren Shen, Sairei To, Shan Chi, Shen Min, Shi Can, Shi Liu Pi, Shou ...
Tópico(s): Poisoning and overdose treatments
2014 - | Journal of Clinical and Translational Hepatology
A.-P. Tsou, Chu-Wen Yang, Chi‐Ying F. Huang, Ricky Chang-Tze Yu, Yuan-Chii G Lee, Cha-Wei Chang, Bo-Rue Chen, Yu‐Fang Chung, Ming-Ji Fann, Chin Wen, Jen-Hwey Chiu, Chen-Kung Chou,
An analytic strategy was followed to identify putative regulatory genes during the development of human hepatocellular carcinoma (HCC). This strategy employed a bioinformatics analysis that used a database search to identify genes, which are differentially expressed in human HCC and are also under cell cycle regulation. A novel cell cycle regulated gene (HURP) that is overexpressed in HCC was identified. Full-length cDNAs encoding the human and mouse HURP genes were isolated. They share 72 and 61% ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2003 - Springer Nature | Oncogene
Jin‐Chuan Sheu, Juei‐Low Sung, Ding‐Shinn Chen, Pei‐Ming Yang, Ming‐Yang Lai, Chue‐Shue Lee, Hey‐Chi Hsu, Che-Nan Chuang, Pan‐Chyr Yang, Teh‐Hong Wang, Jaw‐Town Lin, Cha‐Ze Lee,
The growth rate of 31 asymptomatic hepatocellular carcinomas (diameter less than or equal to 5 cm) discovered in 28 patients by a prospective screening program was determined by real-time ultrasonography over 36-860 days. Except for one tumor that shrank on follow-up, the doubling time ranged from 29 to 398 days, with a median of 117 days, an arithmetic mean of 136 days, and a geometric mean of 110 days. In 17 tumors with more than two measurements, the growth rate remained exponential in nine, declined ...
Tópico(s): Ovarian cancer diagnosis and treatment
1985 - Elsevier BV | Gastroenterology
Cha-Ming Shen, Shi-Chen Lin, Chen-May Huang, Huay-Xan Lin, Chi-Hong Wang,
Abstract This paper presents a judicious reasoning method by coupling passive voltage contrast (PVC) with scanning probe microscopy (SPM) for revealing particular invisible defect modes, which were imperceptible to observe and very difficult to identify by means of traditional physical failure analysis techniques. In order to certify this compound method, it is applied to an implant issue as a case study. Through solving this particular defect mode, whose exact failure position could not be determined ...
Tópico(s): Electron and X-Ray Spectroscopy Techniques
2005 - | Proceedings - International Symposium for Testing and Failure Analysis
... the period. Some notable writings available today are Cha Chi-tso's TSUI WEI LU and LU CH'UN-CH'IU, Ku Yen-wu's MING-CHI SAN-CH'AO YEH-SHIH, Huang Tsung- ...
Tópico(s): Financial Crisis of the 21st Century
1980 - Taylor & Francis | Ming Studies
Harmony R. Reynolds, Derek D. Cyr, C. Noel Bairey Merz, Leslee J. Shaw, Bernard R. Chaitman, William E. Boden, Karen P. Alexander, Yves Rosenberg, Sripal Bangalore, Gregg W. Stone, Claes Held, John A. Spertus, Kaatje Goetschalckx, O.L. Bockeria, Jonathan Newman, Jeffrey S. Berger, Ahmed Elghamaz, Renato D. Lópes, James K. Min, Daniel S. Berman, Michael H. Picard, Raymond Y. Kwong, Robert A. Harrington, Boban Thomas, Sean M. O’Brien, David J. Maron, Judith S. Hochman, Kreton Mavromatis, Jason Linefsky, Todd Q. Miller, Subhash Banerjee, Harmony R. Reynolds, Jonathan Newman, Sripal Bangalore, Robert Donnino, Lawrence M. Phillips, Muhamed Sarić, Khaled Abdul‐Nour, Peter H. Stone, James J. Jang, Gennie Yee, Steven Weitz, Suzanne V. Arnold, James H. O’Keefe, Michael D. Shapiro, Mohammad El‐Hajjar, Mandeep S. Sidhu, Steven Fein, Mikhail Torosoff, Radmila Lyubarova, Sulagna Mookherjee, Krzysztof Drzymalski, Edward O. McFalls, Santiago García, Stefan Bertog, Rizwan A. Siddiqui, Areef Ishani, Ronnell A. Hansen, Michel G. Khouri, Jonathan Goldberg, Richard S. Goldweit, Ronny Cohen, Brooks Mirrer, Victor J. Navarro, David E. Winchester, Marvin W. Kronenberg, Philip Rogal, Christopher McFarren, John F. Heitner, Ira Dauber, Charles R. Cannan, Sriram Sudarshan, Puja K. Mehta, Michael McDaniel, Stamatios Lerakis, Arshed A. Quyyumi, Nanette K. Wenger, Chester M. Hedgepeth, Heather Hurlburt, Alan Rosen, Zakir Sahul, David T. Booth, Steve Leung, Ahmed Abdel‐Latif, Hassan Reda, Khaled M. Ziada, Sampoornima Setty, Rajat S. Barua, Fadi G. Hage, Christiano Caldeira, James E. Davies, Massoud A. Leesar, Jaekyeong Heo, Amy Iskandrian, Firas Al Solaiman, Satinder P. Singh, Khaled Dajani, Mohammad El‐Hajjar, Paul Der Mesropian, Joseph Sacco, Brian McCandless, Marisa Orgera, Mandeep S. Sidhu, Imran Arif, Hanan Kerr, Jorge F. Trejo, Gerald F. Fletcher, Gary E. Lane, Lynn M. Neeson, Pragnesh Parikh, Peter Pollak, Brian P. Shapiro, Kevin Landolfo, Anthony Gemignani, Daniel J. O’Rourke, Judith Meadows, Jason T. Call, Joseph Hannan, Robert M. Bojar, Deepti Kumar, John Mukai, Edward T. Martin, Gabriel Vorobiof, Alec J. Moorman, Scott Kinlay, Robert J. Hamburger, Thomas P. Rocco, Deepak L. Bhatt, Kevin Croce, Jacquelyn A. Quin, Jati Anumpa, Marco A. Zenati, David P. Faxon, Glenn Rayos, Ashraf Seedhom, Lance Sullenberger, G K Kumkumian, Steven P. Sedlis, Robert Donnino, Jeffrey Lorin, Jacqueline Tamis‐Holland, Robert Kornberg, Robert Leber, Souheil Saba, Michael W. Lee, Delano R. Small, Wassim Nona, Patrick Alexander, Iram Rehman, Umesh Badami, Kevin Marzo, Inga H. Robbins, Howard A. Levite, Sanjay Shetty, Mayuri Patel, Glenn S. Hamroff, Raymond W. Little, Brandi D. Zimbelman, Charles Y. Lui, Brigham R. Smith, Daniel P. Vézina, Lillian Khor, Josephine Abraham, David A. Bull, Stephen H. McKellar, David T. Booth, John Kotter, Ahmed Abdel‐Latif, Bob S. Hu, Arthur J. Labovitz, Michael Berlowitz, Philip Rogal, Christopher McFarren, Fadi Matar, Christiano Caldeira, David J. Maron, Fátima Rodríguez, Ingela Schnittger, William F. Fearon, Prakash Deedwania, Kiran Reddy, Joseph Sweeny, Christopher Spizzieri, Claudia P. Hochberg, William D. Salerno, R. Michael Wyman, Amer Zarka, Anil V. Shah, Thomas Haldis, Jeffrey A. Kohn, Saket Girotra, Omar Almousalli, Mayil S. Krishnam, Jeffrey C. Milliken, Pranav M. Patel, Arnold H. Seto, Kevin Harley, Michael Gibson, Byron J. Allen, Rita Coram, Sabu Thomas, Ronald G. Schwartz, Wei Chen, Mahfouz El Shahawy, James M. Stafford, William B. Abernethy, Andrew O. Zurick, Thomas M. Meyer, Ronald G. Morford, Bruce Rutkin, Sabahat Bokhari, Seth I. Sokol, Jay Meisner, Ihab Hamzeh, Arunima Misra, Matthew J. Wall, Veronica Lenges De Rosen, Mahboob Alam, Michael C. Turner, Thomas J. Mulhearn, Arnold P. Good, Nicolas W. Shammas, Robert Ćhilton, Patricia K. Nguyen, Matthew R. Jezior, Paul Gordon, Thomas Crain, Robert Stenberg, Ronald P. Pedalino, Joseph Wiesel, George Juang, Mohammed Al‐Amoodi, David Wohns, Ellis Lader, Michael T. Mumma, Lekshmi Dharmarajan, Joseph F.X. McGarvey, Thomas R. Downes, Gary J. Luckasen, Benjamin Cheong, Srinivasa Potluri, Ronald Mastouri, Jeffery A. Breall, George E. Revtyak, Jonathan W. Bazeley, Dayuan Li, Kenneth N. Giedd, Wayne Old, Francis Burt, Kozhaya Sokhon, Deepika Gopal, Uma Valeti, Jon Kobashigawa, Sajeev Chakanalil Govindan, Rajesh Gopalan Nair, Cholenahally Nanjappa Manjunath, Nagaraja Moorthy, S Manjunath, Suryaprakash Narayanappa, Neeraj Pandit, Ranjit Kumar Nath, S.K. Dwivedi, V.S. Narain, Sharad Chandra, Gurpreet Singh Wander, Rohit Tandon, Sarju Ralhan, Naved Aslam, Abhishek Goyal, Balram Bhargava, Ganesan Karthikeyan, S Ramakrishnan, Sandeep Seth, Rakesh Yadav, Sandeep Singh, Ambuj Roy, Neeraj Parakh, Sunil Kumar Verma, Rajiv Narang, Sundeep Mishra, Nitish Naik, Gautam Sharma, Shiv Kumar Choudhary, Chetan Patel, Gurpreet Singh Gulati, Sanjeev Sharma, Vinay K. Bahl, Anoop Mathew, Eapen Punnoose, Milind Gadkari, Siddharth Gadage, Tapan Umesh Pillay, Santhosh Satheesh, Atul Mathur, Upendra Kaul, Johann Christopher,
Women with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. We explored sex differences in revascularization, guideline-directed medical therapy, and outcomes among patients with chronic coronary disease with ischemia on stress testing, with and without invasive management.
Wiley
Chih‐Liang Chu, Chin-Tu Lu, Hung‐Chi Chen, Jhih-Sian Ke, Cha'o-Ming Chang,
This study develops a micro-CMM incorporating a scanning touch probe and a high-precision coplanar platform. The measurement performance of the proposed system was enhanced through the use of a rigid aluminum double-arch-bridge structure to support the scanning touch probe. For the working stage, a linear motor was used for long-stroke positioning and a piezoelectric actuator was then employed to fine-tune the positioning so as to achieve a requirement of highprecision. The platform has two characteristics: ( ...
Tópico(s): Adhesion, Friction, and Surface Interactions
2013 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Hsi‐Yu Yu, Ming‐Hsien Lin, Lian‐Yu Lin, Chih‐Hsien Wang, Nai‐Hsin Chi, Yih‐Sharng Chen,
Asian patients on warfarin therapy usually have lower international normalized ratio (INR) intensities than those recommended by Western clinical practice guidelines. This study evaluated whether a high INR reduces the incidence of thromboembolism (TE) or bleeding events in Asian patients with high CHA2DS2-VASc scores after valve surgery.Methods and Results:Data of adult patients after valve surgery were retrieved from an integrated healthcare information system of a single hospital between 2014 and ...
Tópico(s): Acute Myocardial Infarction Research
2018 - Japanese Circulation Society | Circulation Journal
Yi-Ta Tsai, Mei‐Jen Chuang, Shou‐Hung Tang, Sheng‐Tang Wu, Yu‐Chi Chen, Guang‐Huan Sun, Pei‐Wen Hsiao, Shih‐Ming Huang, Hwei‐Jen Lee, Cheng‐Ping Yu, Jar‐Yi Ho, Hui‐Kuan Lin, Ming-Rong Chen, Chung-Chih Lin, Sun‐Yran Chang, Victor C. Lin, Dah‐Shyong Yü, Tai‐Lung Cha,
Mitochondria are the powerhouses of cells. Mitochondrial C-Raf is a potential cancer therapeutic target, as it regulates mitochondrial function and is localized to the mitochondria by its N-terminal domain. However, Raf inhibitor monotherapy can induce S338 phosphorylation of C-Raf (pC-Raf(S338)) and impede therapy. This study identified the interaction of C-Raf with S308 phosphorylated DAPK (pDAPK(S308)), which together became colocalized in the mitochondria to facilitate mitochondrial remodeling. ...
Tópico(s): Cancer Mechanisms and Therapy
2015 - American Association for Cancer Research | Cancer Research
Nai-Yu Chi, Ho‐Ming Su, Wen-Hsien Lee, Wei‐Chung Tsai, Ying‐Chih Chen, Tzu-Chieh Lin, Ye‐Hsu Lu, Chee‐Siong Lee, Tsung‐Hsien Lin, Wen‐Ter Lai, Sheng‐Hsiung Sheu, Po‐Chao Hsu,
Abnormal low and high ankle brachial index (ABI) is regarded as peripheral artery disease (PAD) which has extremely high morbidity and mortality. How to identify high-risk PAD patients with increased mortality is very important to improve the outcome. CHADS2, R2CHADS2, and CHA2DS2-VASc score are clinically useful scores to evaluate the annual risk of stroke in patients with atrial fibrillation. However, there was no literature discussing the usefulness of these scores for cardiovascular (CV) and all- ...
Tópico(s): Hemodynamic Monitoring and Therapy
2020 - Ivyspring International Publisher | International Journal of Medical Sciences
Shih-Ting Cha, Ching‐Ting Tan, Cheng-Chi Chang, Chia‐Yu Chu, Wei‐Jiunn Lee, Been-Zen Lin, Ming‐Tsan Lin, Min‐Liang Kuo,
In this Article, we reported that G9a promotes colorectal-cancer-initiating cell self-renewal and function by repressing Let-7b expression in a manner independent of its enzymatic activity, thereby activating K-RAS and β-catenin signalling.
Tópico(s): Cancer Mechanisms and Therapy
2016 - Nature Portfolio | Nature Cell Biology
Chi-Pei Lu, Bing‐Yue Tsui, Cheng-Kei Luo, Cha-Hsin Lin, Pei-Jer Tzeng, Ching-Chiun Wang, Ming-Jinn Tsai,
In this work, high-performance TiN metal nanocrystal nonvolatile memories using a poly-Si gate and a blocking dielectric layer with trigate structure are fabricated on silicon-on-insulator substrate. Devices with moderate transistor performance and superior memory properties are demonstrated. A memory window as high as is achieved after Program/Ease (P/E) operation at for , with only 18 and 33% charge loss at room temperature and at after storage. Only window shift and almost no window narrowing after ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2009 - Electrochemical Society | Electrochemical and Solid-State Letters
Chi-Pei Lu, Cheng-Kei Luo, Bing‐Yue Tsui, Cha-Hsin Lin, Pei-Jer Tzeng, Ching-Chiun Wang, Ming-Jinn Tsai,
In this study, a charge-trapping-layer-engineered nanoscale n-channel trigate TiN nanocrystal nonvolatile memory was successfully fabricated on silicon-on-insulator (SOI) wafer. An Al2O3 high-k blocking dielectric layer and a P+ polycrystalline silicon gate electrode were used to obtain low operation voltage and suppress the back-side injection effect, respectively. TiN nanocrystals were formed by annealing TiN/Al2O3 nanolaminates deposited by an atomic layer deposition system. The memory characteristics ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2009 - Institute of Physics | Japanese Journal of Applied Physics
Tzong‐Yow Tsai, Zhi‐Cheng Lee, Jong‐Rong Chen, Chi‐Chung Chen, Yen‐Cheng Fang, Ming‐Hong Cha,
Abstract An ultra‐short‐wavelength filter using photonic band gap (PBG) mode‐related dispersion in a two‐moded waveguide is proposed. It is verified using the finite‐difference time‐domain (FDTD) method, such that two channels on the PBG edges are affected by opposite dispersive effects and can be separated by an ultra‐short coupler length much shorter than the required length without the assistance of PBG dispersion. © 2005 Wiley Periodicals, Inc. Microwave Opt Technol Lett 46: 225–227, 2005; Published ...
Tópico(s): Advanced Photonic Communication Systems
2005 - Wiley | Microwave and Optical Technology Letters
J. Donald Easton, Maria Aunes, Gregory W. Albers, Pierre Amarenco, Sara Bokelund-Singh, Hans Denison, Scott R. Evans, Peter Held, Maria Jahreskog, Jenny Jonasson, Kazuo Minematsu, Yongjun Wang, K.S. Lawrence Wong, S. Claiborne Johnston, Sebastiá Ameriso, Geoffrey Donnan, Ayrton Massaro, Michael D. Hill, Norio Tanahashi, Ludmila Stakhovskaya, Jong-Sung Kim, Nils Wahlgren, Tsong Hai Lee, Kursad Kutluk, Sergii Moskovko, Scott Kasner, Daniel Laskowitz, Wayne Clark, Huy Thang Nguyen, Sebastian Ameriso, Sandra Lepera, Marina Romano, David Paulon, Pablo Ioli, Cristina Zurru, Guadalupe Bruera, Lorena Jure, Francisco Klein, Guillermo Povedano, Christopher Levi, Thanh Viet Phan, Romesh Markus, Craig Anderson, Arman Sabet, Stephen M. Davis, Andrew Lee, Timothy Klein, Andrew Wong, Martín Krause, Jim Jannes, Tissa Wijeratne, Robin Lemmens, Dimitri Hemelsoet, André Peeters, Philippe Tack, Peter Vanacker, Patrice Laloux, William van Landegem, Geert Vanhooren, Philippe Desfontaines, Marc van Orshoven, Fábio Oliveira, Mauricio Friedrich, Rosane Brondani, Rubens Gagliardi, Fabio Fabio, Maria Dracoulakis, Rodrigo Bazan, Luiz Marrone, Octavio Pontes Neto, Gisele Silva, Pedro Kowacs, Ekaterina Titianova, Paraskeva Stamenova, Marin Daskalov, Ivan Staikov, Dimo Baldaranov, Dimitar Maslarov, Hristo Lilovski, Plamen Petkov, Neli Petrova, Radoslav Mavrov, Veska Markova, Valeria Petrova, Tanya Beleva, Borislav Kralev, Nikolay Sotirov, Veska Lekova, Hristo Hristov, Vera Ermenkova, Lyudmil Mateev, Rumeliya Mitkova, Liybomir Haralanov, Rosen Ikonomov, Margarita Mihailova, Ivan Georgiev, Ashfaq Shuaib, Vladimir Hachinski, Martin Boulanger, Sharan Mann, Ayman K.M. Hassan, Ariane Mackey, Bijoy Menon, Jeffrey Minuk, Muzaffar Siddiqui, Marsha Eustace, Lucia Vieira, Daniel Selchen, Grant Stotts, Pablo Lavados, Angel Castro, Kristo Gasic, Rodrigo Rivas, Pablo Sánchez, Andres Roldan, Ingrid Grossmann, Christian Figueroa, Jim Li, Xiaolin Xu, Huisheng Chen, Xiaohong Li, Yi Yang, Chunsheng Zhang, Baojun Wang, Guanglai Li, Dong Wang, Hong Li, Yamei Tang, Anding Xu, Yanjiang Wang, Hong Hong, Zhi Song, Xiaoping Jin, Fuling Yan, Weihong Zheng, Xiaoping Wang, Dong Dong, Zhongxin Zhao, Baorong Zhang, Wangtao Wang, Guoqiang Wen, Guozhong Li, Dong Xu, Xiangyang Tian, Zhaohui Zhang, Xu Xu, Kaixiang Li, Jun Chen, Ondrej Skoda, David Skoloudik, Edvard Ehler, Daniel Vaclavik, Daniel Sanak, Sylva Klimosova, Eva Vitkova, Jan Fiksa, Robert Mikulik, Jiri Neumann, Richard Plny, Didier Leys, Igor Sibon, Jean-Louis Mas, Sonia Alamowitch, Fernando Pico, Marie-Hélène Mahagne, Emmanuel Touzé, Wilfried Vadot, Stephane Vannier, Norbert Norbert, Yves Samson, Pierre Garnier, Emmanuel Ellie, Benoit Guillon, Serge Timsit, Maurice Giroud, Philippe Philippeau, Aude Bagan-Triquenot, Valérie Wolff, Nicolas Raposo, Severine Debiais, Jérôme Grimaud, Stéphane Illouz, Didier Smadja, Cédric Urbanczyk, Joachim Röther, Jörg Berrouschot, Christian Weimar, Georg Gahn, Hassan Hassan, Sven Klimpe, Darius Nabavi, Jörg Glahn, Martin Köhrmann, Lars Krause, Christoph Terborg, Peter Urban, Thorsten Steiner, Andreas Ferbert, Rainer Dziewas, Günter Seidel, Götz Thomalla, Chen Li, Wing Chi Fong, Raymond Cheung, Szegedi Norbert, Krisztián Pozsegovits, Attila Valikovics, Gyula Pánczél, Csilla Rózsa, László Németh, Péter Diószeghy, Csaba Óváry, Attila Csányi, Levente Kerényi, Valéria Nagy, Sámuel Komoly, Dániel Bereczki, Sándor Molnár, István Kondákor, David Tanné, Guy Raphaeli, Gregory Telman, Natan Bornstein, Ronen Leker, Yair Lampl, Giancarlo Agnelli, Francesco Corea, Donata Guidetti, Giovanni Malferrari, Marc Marcheselli, Giuseppe Micieli, Andrea Zini, Vincenzo Di Lazzaro, Carlo Gandolfo, Andrea Salmaggi, Rossana Tassi, Maurizia Rasura, Giovanni Orlandi, Giancarlo Comi, Stefano Ricci, Michel Michel, Maria Delodovici, Paolo Bovi, Domenico Consoli, Kimiaki Kim, Tsuneo Fujita, Hideyuki Kurihara, Chikashi Maruki, Takeshi Hayashi, Tsuneaki Ogiichi, Morio Kumagai, Katsunobu Takenaka, Kazunori Toyoda, Kazuhiro Takamatsu, Ryo Ogami, Shigenari Kin, Takeshi Aoki, Katsumi Takizawa, Shigehiro Omori, Takehiko Umezawa, Yasuyuki Toba, Yutaka Nonoyama, Hidemitsu Nakagawa, Takashi Naka, Masanori Mas, Shuichi Matsumoto, Tsutomu Hitotsumatsu, Tatsuya Shingaki, Satoshi Okuda, Mamoru Ota, Nobuyuki Sakai, Takeshi Yamada, Jun Niwa, Hitoshi Fujita, Akihito Moriki, Yoshihisa Fukushima, Takahisa Mori, Atsushi Sato, Yoshikazu Kusano, Michiya Kubo, Masashi Mas, Takao Ooasa, Takafumi Nishizaki, Naoki Kitagawa, Yasuhiro Manabe, Akira Yoshioka, Takato Kagawa, Toshikazu Ichihashi, Hideki Matsuoka, Yasuhiro Ito, Hitonori Takaba, Hisatoshi Saito, Kazumasa Fukuda, En Endo, Minoru Kidooka, Toshitaka Umemura,
Background: Patients with minor acute ischemic stroke or transient ischemic attack are at high risk for subsequent stroke, and more potent antiplatelet therapy in the acute setting is needed. However, the potential benefit of more intense antiplatelet therapy must be assessed in relation to the risk for major bleeding. The SOCRATES trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes) was the first trial with ticagrelor in patients with acute ischemic ...
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