Claudia Bazzini, Lorena Benedetti, Davide Antonio Civello, Chiara Zanoni, V. Rossetti, Davide Marchesi, Maria Lisa Garavaglia, Markus Paulmichl, Maura Francolini, G. Meyer, Simona Rodighiero,
To optimise the efficiency of cell machinery, cells can use the same protein (often called a hub protein) to participate in different cell functions by simply changing its target molecules. There are large data sets describing protein-protein interactions (“interactome”) but they frequently fail to consider the functional significance of the interactions themselves. We studied the interaction between two potential hub proteins, ICln and 4.1R (in the form of its two splicing variants 4.1R80 and 4.1R135), ...
Tópico(s): RNA and protein synthesis mechanisms
2014 - Public Library of Science | PLoS ONE