Royce Ε. Ballinger, Gordon D. Schrank,
... 224139Siao Ye, Krishna N. Badhiwala, Jacob T. Robinson, Won Hee Cho, Evan Siemann Thermal plasticity of a freshwater cnidarian ...
Tópico(s): Species Distribution and Climate Change
1970 - University of Chicago Press | Physiological Zoology
Siao Ye, Krishna N. Badhiwala, Jacob T. Robinson, Won Hee Cho, Evan Siemann,
Understanding factors affecting the susceptibility of organisms to thermal stress is of enormous interest in light of our rapidly changing climate. When adaptation is limited, thermal acclimation and deacclimation abilities of organisms are critical for population persistence through a period of thermal stress. Holobionts (hosts plus associated symbionts) are key components of various ecosystems, such as coral reefs, yet the contributions of their two partners to holobiont thermal plasticity are ...
Tópico(s): Parasite Biology and Host Interactions
2019 - Springer Nature | The ISME Journal
Won-hee Cho, Seon-Hwa Park, Seul-Ki Choi, Su Woong Jung, Kyung Hwan Jeong, Yang‐Gyun Kim, Ju-Young Moon, Sung-Jig Lim, Ji‐Youn Sung, Jong Hyun Jhee, Ho Jun Chin, Bum Soon Choi, Sang Ho Lee,
Approximately 5% of patients with IgA nephropathy (IgAN) exhibit mild mesangial lesions with acute onset nephrotic syndrome and diffuse foot process effacement representative of minimal change disease (MCD). It is not clear whether these unusual cases of IgAN with MCD (IgAN-MCD) are variant types of IgAN or coincidental deposition of IgA in patients with MCD. In a retrospective multicenter cohort study of 18 hospitals in Korea, we analyzed 46 patients with IgAN-MCD. Patients with endocapillary proliferation, ...
Tópico(s): Chronic Kidney Disease and Diabetes
2020 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Matthia Helble, Cyn‐Young Park, Won Hee Cho, Sol Francesca Cortes,
Recent surveys indicate that people long to travel again after many months of restricted movements.Thus, demand for travel that is above historical trends can be seen for vaccinated people.2 Aside from allowing travel, such passes could unlock incentives in the domestic setting.Just like Israel's "Green Pass," a vaccine pass may eventually be needed to enjoy activities such as going to restaurants, gyms, and theaters, which have otherwise been restricted due to health precautions like social distancing ( ...
Tópico(s): Vaccine Coverage and Hesitancy
2021 - | ADB briefs
Su Woong Jung, Won-Hee Cho, Jung-Woo Seo, Yang‐Gyun Kim, Ju-Young Moon, Jin Sug Kim, Chan‐Duck Kim, Byung Ha Chung, Jae Berm Park, Yeong Hoon Kim, Sang Ho Lee,
Abstract Background Urine exosomal bkv-miR-B1-5p is associated with BK virus (BKV) nephropathy (BKVN); however, its posttransplantation changes and predictability for BKVN have not been determined in kidney transplant recipients (KTRs). Methods Urine exosomal bkv-miR-B1-5p and urine and plasma BKV DNA were measured at 2 weeks and 3, 6, and 12 months posttransplant in 83 KTRs stratified into biopsy-proven or presumptive BKVN, BKV viruria, and no evidence of BKV reactivation. Joint model, multivariable ...
Tópico(s): Parvovirus B19 Infection Studies
2022 - Oxford University Press | The Journal of Infectious Diseases
Su-Hyeon Kim, Eun‐Ran Park, Eugene Cho, Won Hee Jung, Ju‐Yeon Jeon, Hyun-Yoo Joo, Kee-Ho Lee, Hyunjin Shin,
... Hyeon Kim 1 , Eun-Ran Park 1 , Eugene Cho 1 , Won-Hee Jung 1 , Ju-Yeon Jeon 1 , Hyun-Yoo ...
Tópico(s): RNA Interference and Gene Delivery
2016 - Impact Journals LLC | Oncotarget
Kipyo Kim, Su Woong Jung, Won-Hee Cho, Haena Moon, Kyung Hwan Jeong, Jin Sug Kim, Sang Ho Lee, Shin Young Ahn, Dong Ho Yang, Hong Joo Lee, Dong-Young Lee, Ju-Young Moon, Yang‐Gyun Kim,
<b><i>Background:</i></b> Cell-free mitochondrial DNA (cf-mtDNA) has recently been in the spotlight as an endogenously produced danger molecule that can potentially elicit inflammation. However, its clinical and prognostic implications are uncertain in patients undergoing hemodialysis. <b><i>Methods:</i></b> We examined the association of baseline cf-mtDNA categorized as tertiles with health-related quality of life (HRQOL), inflammatory cytokines, and mortality ...
Tópico(s): Sepsis Diagnosis and Treatment
2020 - Karger Publishers | Blood Purification
Saelin Oh, Won‐Hee Jee, Shiau‐Shan Cho, S.H Kim, H.-S. Kang, Kyung Nam Ryu, C.S Cho,
This study was to describe the findings of osteonecrosis in patients with SLE at MR and scintigraphic imaging. Among 415 patients with SLE, 37 patients were diagnosed to have osteonecrosis. MR images and bone scintigraphs were analyzed for sites of involvement, signal intensity, bilaterality and multiplicity. MR imaging features of osteonecrosis in patients with SLE included isointense signal intensity relative to adjacent bone marrow, hypointense rim, marginal enhancement and unusual involvement ...
Tópico(s): Osteomyelitis and Bone Disorders Research
2004 - Elsevier BV | Clinical Imaging
Won Hee Lee, Hyung Joon Cho, William E. Sonntag, Yong Woo Lee,
The etiology of radiation-induced cerebrovascular rarefaction remains unknown. In the present study, we examined the effect of whole-brain irradiation on endothelial cell (EC) proliferation/apoptosis and expression of various angiogenic factors in rat brain. F344×BN rats received either whole-brain irradiation (a single dose of 10 Gy γ rays) or sham irradiation and were maintained for 4, 8 and 24 h after irradiation. Double immunofluorescence staining was employed to visualize EC proliferation/apoptosis ...
Tópico(s): Axon Guidance and Neuronal Signaling
2011 - Radiation Research Society | Radiation Research
Won Hee Seo, E.R. Cho, Robert J. Thomas, S‐Y An, Jae‐Jun Ryu, Hyung Jun Kim, Chol Shin,
Background and Objective Periodontitis is becoming a highly prevalent disease worldwide. Obstructive sleep apnea ( OSA ) is a common disorder that is characterized by repeated disruptions in breathing during sleep, and mouth breathing is a common characteristic among patients with OSA . We aimed to assess the hypothesis that OSA is associated with the onset and progression of periodontal disease. Material and Methods This is a cross‐sectional study of a total of 687 participants (460 men and 227 women), ...
Tópico(s): Salivary Gland Disorders and Functions
2012 - Wiley | Journal of Periodontal Research
Won Hee Kim, Joo Young Cho, Weon Jin Ko, Sung Pyo Hong, Ki Baik Hahm, Jun‐Hyung Cho, Tae Hee Lee, Su Jin Hong,
We evaluated whether manometric subtype is associated with treatment outcome in patients with achalasia treated by peroral endoscopic myotomy (POEM).High-resolution manometry data and Eckardt scores were collected from 83 cases at two tertiary referral centers where POEM is performed. Manometric tracings were classified according to the three Chicago subtypes.Among the 83 cases, 48 type I, 24 type II, and 11 type III achalasia cases were identified. No difference was found in pre-POEM Eckardt score, ...
Tópico(s): Eosinophilic Esophagitis
2017 - Korean Association for the Study of the Liver | Gut and Liver
Nan Hee Kim, Jiyun Ahn, Yong Min Choi, Hyo Jung Son, Won Hee Choi, Hyun Joo Cho, Ji Hee Yu, Ji A Seo, Young Jin Jang, Chang Hwa Jung, Tae Youl Ha,
Altered microRNA (miRNA) expression is associated with the pathophysiology of obesity; however, little is known about the miRNAs commonly dysregulated in the blood and visceral fat tissue of obese patients. This study compared the circulating and visceral fat miRNA expression in subjects with and without obesity.For the circulating miRNA study, 20 healthy control and 30 obese subjects were recruited. For the tissue miRNA expression study, omental fat tissue was collected in ten female subjects each ...
Tópico(s): Cancer-related molecular mechanisms research
2019 - Elsevier BV | Clinical Nutrition
Jihyun Yang, Vu Minh Phan, Chang-Kyu Heo, Hau Van Nguyen, Won-Hee Lim, Eun‐Wie Cho, Haryoung Poo, Tae Seok Seo,
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has threatened public health globally, and the emergence of viral variants has exacerbated an already precarious situation. To prevent further spread of the virus and determine government action required for virus control, accurate and rapid immunoassays for SARS-CoV-2 diagnosis are urgently needed. In this study, we generated monoclonal antibodies (mAbs) against the SARS-CoV- ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2023 - Elsevier BV | Sensors and Actuators B Chemical
Sebastin Raveendar, Jung Ro Lee, Jae-Wan Park, Gi-An Lee, Young‐Ah Jeon, Wonhee John Lee, Gyu‐Taek Cho, Kyung‐Ho Ma, Sok‐Young Lee, Jong‐Wook Chung,
... Wan Park, Gi-An Lee, Young-Ah Jeon, Won-Hee Lee, Gyu-Taek Cho, Kyung-Ho Ma, Sok-Young Lee, and Jong- ...
Tópico(s): Agricultural pest management studies
2015 - | Plant Breeding and Biotechnology
Weiguo Zhao, Jong‐Wook Chung, Young‐Il Cho, Won-Hee Rha, Gi-An Lee, Kyung‐Ho Ma, Sin-Hee Han, Kyong-Hwan Bang, Chung-Berm Park, Seong-Min Kim, Yong‐Jin Park,
Tópico(s): Yeasts and Rust Fungi Studies
2010 - Elsevier BV | Comptes Rendus Biologies
Yong Woo Lee, Hyung Joon Cho, Won Hee Lee, William E. Sonntag,
Radiation therapy, the most commonly used for the treatment of brain tumors, has been shown to be of major significance in tumor control and survival rate of brain tumor patients. About 200,000 patients with brain tumor are treated with either partial large field or whole brain radiation every year in the United States. The use of radiation therapy for treatment of brain tumors, however, may lead to devastating functional deficits in brain several months to years after treatment. In particular, ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2012 - Korean Society of Applied Pharmacology | Biomolecules & Therapeutics
Dae Kyu Shin, Sun Young Shin, Chi Young Park, Sun Jin, Yang Hyun Cho, Won Hee Kim, Chang‐Il Kwon, Kwang Hyun Ko, Ki Baik Hahm, Pil Won Park, Jong Woo Kim, Sung Pyo Hong,
Colonoscopic perforations have been managed with exploratory laparotomy, and have resulted in some morbidity and mortality. Recently, laparoscopic surgery is commonly performed for this purpose. The aim of this study was to compare the outcomes of several management strategies for iatrogenic colonoscopic perforations.We retrospectively reviewed the medical records of patients who had been treated for colonoscopic perforation between January 2004 and April 2013 at CHA Bundang Medical Center in Korea. ...
Tópico(s): Gastric Cancer Management and Outcomes
2016 - Korean Society of Gastrointestinal Endoscopy | Clinical Endoscopy
Jung Ho Park, Young Hee Sung, Mi Sook Song, Jung Sook Cho, Won Hee Sim,
A nursing activity classification for hospitalized patients was performed based on an article review regarding nursing definition and nursing activity classification system. The study was conducted as follows: 1) Taxonomy was developed by the research team through the Delphi process and review artic...
Tópico(s): Healthcare Education and Workforce Issues
2000 - | Daehan ganho haghoeji
Young-Ho Seo, Tae‐Hee Cho, Chae-Kyu Hong, Mi-Sun Kim, Sung-Ja Cho, Won-Hee Park, In-Sook Hwang, Moo‐Sang Kim,
We tested for residual pesticide levels in dried vegetables in Seoul, Korea. A total of 100 samples of 13 different types of agricultural products were analyzed by a gas chromatography-nitrogen phosphate detector (GC-NPD), an electron capture detector (GC-μECD), a mass spectrometry detector (GC-MSD), and a high performance liquid chromatography-ultraviolet detector (HPLC-UV). We used multi-analysis methods to analyze for 253 different pesticide types. Among the selected agricultural products, residual ...
Tópico(s): Pesticide Exposure and Toxicity
2013 - Korean Society of Food Science and Nutrition | Preventive Nutrition and Food Science
Hyung Joon Cho, Won Hee Lee, Olivia Hwang, William E. Sonntag, Yong Woo Lee,
The present study was designed to investigate our hypothesis that NADPH oxidase plays a role in radiation-induced pro-oxidative and pro-inflammatory environments in the brain.C57BL/6 mice received either fractionated whole brain irradiation or sham-irradiation. The mRNA expression levels of pro-inflammatory mediators, such as TNF-α and MCP-1, were determined by quantitative real-time RT-PCR. The protein expression levels of TNF-α, MCP-1, NOX-2 and Iba1 were detected by immunofluorescence staining. ...
Tópico(s): Anesthesia and Neurotoxicity Research
2017 - Taylor & Francis | International Journal of Radiation Biology
Mélissa Caza, Guanggan Hu, Erik David Nielson, Minsu Cho, Won Hee Jung, James W. Kronstad,
The battle for iron between invading microorganisms and mammalian hosts is a pivotal determinant of the outcome of infection. The pathogenic fungus, Cryptococcus neoformans, employs multiple mechanisms to compete for iron during cryptococcosis, a disease primarily of immunocompromised hosts. In this study, we examined the role of endocytic trafficking in iron uptake by characterizing a mutant defective in the Sec1/Munc18 (SM) protein Vps45. This protein is known to regulate the machinery for vesicle ...
Tópico(s): Phytoplasmas and Hemiptera pathogens
2018 - Public Library of Science | PLoS Pathogens
Sarath Babu Nukala, Jordan Jousma, Yoonje Cho, Won Hee Lee, Sang‐Ging Ong,
Abstract Cancer is one of the leading causes of morbidity and mortality worldwide. Significant improvements in the modern era of anticancer therapeutic strategies have increased the survival rate of cancer patients. Unfortunately, cancer survivors have an increased risk of cardiovascular diseases, which is believed to result from anticancer therapies. The emergence of cardiovascular diseases among cancer survivors has served as the basis for establishing a novel field termed cardio-oncology. Cardio- ...
Tópico(s): MicroRNA in disease regulation
2022 - BioMed Central | Cell & Bioscience
Peey‐Sei Kok, Doah Cho, Won-Hee Yoon, G. Ritchie, Ian C. Marschner, Sarah J. Lord, Michael Friedlander, John Simes, Chee Khoon Lee,
Importance Progression-free survival (PFS) rate at 6 months has been proposed as a potential surrogate for overall survival (OS) rate at 12 months for immune checkpoint inhibitor (ICI) trials but requires further assessment for validation. Objective To validate 6-month PFS and objective response rate (ORR) as estimators of 12-month OS in the ICI arms of randomized clinical trials (RCTs). Data Sources Electronic databases (Medline, EMBASE, and the Cochrane Central Register of Controlled Trials) were searched for ...
Tópico(s): Lung Cancer Treatments and Mutations
2020 - American Medical Association | JAMA Network Open
Eugene Cho, Won Hee Jung, Hyun-Yoo Joo, Eun‐Ran Park, Mi‐Yeon Kim, Su-Bin Kim, Kwang Seok Kim, Young Bin Lim, Kee Ho Lee, Hyun Jin Shin,
Cluh is a cytosolic protein that is known to specifically bind the mRNAs of nuclear-encoded mitochondrial proteins and play critical roles in mitochondrial biogenesis. Here, we report the role of Cluh in adipogenesis. Our study shows that mRNA expression of Cluh is stimulated during adipogenesis, and that cAMP/Creb signalling increases its transcription. Cluh depletion impaired proper adipocyte differentiation, with reductions seen in lipid droplets and adipogenic marker gene expression. Interestingly, ...
Tópico(s): Peroxisome Proliferator-Activated Receptors
2019 - Nature Portfolio | Scientific Reports
Hyeri Yang, Da-eun Kim, Won-Hee Jang, Susun An, Sun-A Cho, Mi-Sook Jung, Ji Eun Lee, Kyung-Wook Yeo, Sang Bum Koh, Tae-Cheon Jeong, Mi-Jeong Kang, Young-Jin Chun, Su-Hyon Lee, Kyung‐Min Lim, SeungJin Bae,
Here, we report the results of a prevalidation trial for an in vitro eye irritation test (EIT) using the reconstructed human cornea-like epithelium, MCTT HCE™. The optimal cutoff to determine irritation in the prediction model was established at 35% with the receiver operation characteristics(ROC) curve for 126 substances. Within-lab(WL) and between-lab(BL) reproducibility was tested for 20 reference substances by 3 participating laboratories. Viability data described by mean±SD or ±1/2 difference ...
Tópico(s): Meta-analysis and systematic reviews
2016 - Elsevier BV | Toxicology in Vitro
Won Hee Jung, Daniel Croll, Jae Hoon Cho, Yu Ri Kim, Yang Won Lee,
Summary Advances in culture‐independent sequencing methods have been utilised in recent studies to understand the phylogenetic composition of the human microbiome of healthy and diseased skin. Allergic rhinitis ( AR ) is an inflammatory condition of the nasal cavity caused by environmental allergens. Although nasal microbial communities have been considered important contributors in human health, no studies to date have comprehensively compared fungal communities (mycobiome) of the nasal vestibule using ...
Tópico(s): Dermatology and Skin Diseases
2015 - Wiley | Mycoses
Jessica A. Weber, Seung Gu Park, Victor Luria, Sungwon Jeon, Hak‐Min Kim, Yeonsu Jeon, Youngjune Bhak, Je Hun Jun, Sang Wha Kim, Won Hee Hong, Semin Lee, Yun Sung Cho, Amir Karger, John W. Cain, Andrea Manica, Soonok Kim, Jae-Hoon Kim, Jeremy S. Edwards, Jong Bhak, George M. Church,
Significance We sequenced and analyzed the genome of the endangered whale shark, the largest fish on Earth, and compared it to the genomes of 84 other species ranging from yeast to humans. We found strong scaling relationships between genomic and physiological features. We posit that these scaling relationships, some of which were remarkably general, mold the genome to integrate metabolic constraints pertaining to body size and ecological variables such as temperature and depth. Unexpectedly, we ...
Tópico(s): Fish biology, ecology, and behavior
2020 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Ju Sung Lee, Leo Adrianne Paje, Won‐Hee Choi, Eun Ju Cho, Hyun Young Kim, Sonia D. Jacinto, Sanghyun Lee,
Abstract Flavonoids present in the leaves of lotus ( Nelumbo nucifera ) grown in different regions of South Korea (Yeongcheon, Haenam, and Seocheon) and at different harvest times (July to September) were determined. Flavonoid contents in lotus extracts were identified and analyzed using high-performance liquid chromatography (HPLC). The HPLC results revealed that the flavonoid contents of the lotus extracts varied at different harvesting times, with the highest content in July. Analysis of the flavonoid ...
Tópico(s): Phytochemistry and biological activity of medicinal plants
2020 - Springer Nature | Applied Biological Chemistry
Hyun Soo Kim, Won‐Hee Jee, Kyung Nam Ryu, Kil Ho Cho, Jin‐Suck Suh, Jae‐Hyun Cho, Yun Sun Choi, Sung Moon Lee, Jong Min Lee, Mi Sook Sung, Jee Young Kim, Eun Sun Jung, Yang-Guk Chung, In-Young Ok,
Chondromyxoid fibroma is a rare benign primary bone tumor of cartilage. Despite a characteristic radiographic appearance, chondromyxoid fibroma with atypical radiographic findings may mimic more common tumors.To describe the MR findings of chondromyxoid fibroma.MR images of 19 histopathologically confirmed chondromyxoid fibromas were retrospectively analyzed for signal intensity, periosteal reaction, adjacent abnormal bone marrow and soft tissue signal, and patterns of contrast enhancement.All cases ...
Tópico(s): Sarcoma Diagnosis and Treatment
2011 - SAGE Publishing | Acta Radiologica
Hee‐Bum Yang, Wing-yee Liu, Won‐Hee Kang, Jin‐Hee Kim, Hwa Jin Cho, Jae-hyung Yoo, Byoung‐Cheorl Kang,
Tópico(s): Agricultural pest management studies
2011 - Springer Science+Business Media | Molecular Breeding