Daniel Reim, Yun Suk Choi, Hong Man Yoon, Boram Park, Bang Wool Eom, Myeong‐Cherl Kook, Keun Won Ryu, Il Ju Choi, Jungnam Joo, Young–Woo Kim,
Background Prognosis of alpha-fetoprotein positive gastric cancer (AFPP-GC) remains elusive so far due to disparities in cohort size and baseline characteristics in previous studies. A propensity score matching (PSM) analysis as well as multivariable model was performed for unbiased evaluation of the outcome in AFPGC. Methods Among 3034 gastric cancer patients who underwent curative gastric cancer surgery (R0, M0) at the National Cancer Center, Korea between 2002 and 2007, we identified 97 patients ...
Tópico(s): Gastric Cancer Management and Outcomes
2017 - Elsevier BV | European Journal of Surgical Oncology
Bang Wool Eom, Jun Yu, Keun Won Ryu, Myeong‐Cherl Kook, Young‐Il Kim, Soo‐Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi, Hong Man Yoon, Young–Woo Kim,
Tópico(s): Gastrointestinal Tumor Research and Treatment
2015 - Springer Science+Business Media | Annals of Surgical Oncology
Stress fractures result from abnormal stresses imposed on normal bones by the continued and repeated actions of muscles or from normal stresses imposed on abnormal bones. The risk factors that can cause such stress fractures include excessive use, such as, in soldiers or athletes, nutritional deficiencies, and endocrine disorders. In addition, disease may arise from long-standing rheumatoid arthritis, osteoporosis, corticosteroid therapy, joint stiffness or contracture, or the correction of angular ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2011 - Springer Nature | Journal of Orthopaedics and Traumatology
Soo‐Jeong Cho, Il Ju Choi, Myeong‐Cherl Kook, Hong Man Yoon, S. Park, C. G. Kim, J. Y. Lee, J H Lee, Keun Won Ryu, Young–Woo Kim,
Background Helicobacter pylori eradication is recommended for early gastric cancer (GC) patients after resection. Aim To evaluate whether H. pylori eradication improves glandular atrophy and intestinal metaplasia (IM) in GC patients undergoing subtotal gastrectomy. Methods This randomised, double-blind trial was performed in tertiary care setting. Distal GC patients with H. pylori infection were randomised to receive proton pump inhibitor-based triple therapy or placebo. The histology was evaluated ...
Tópico(s): Gastroesophageal reflux and treatments
2013 - Wiley | Alimentary Pharmacology & Therapeutics
Jung Hwan Lee, Boram Park, Jungnam Joo, Myeong‐Cherl Kook, Young‐Il Kim, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu, Young–Woo Kim, Soo‐Jeong Cho,
The effects of obesity on prognosis in gastric cancer are controversial.To evaluate the association between body mass index (BMI) and mortality in patients with gastric cancer.A single-institution cohort of 7765 patients with gastric cancer undergoing curative gastrectomy between October 2000 and June 2016 was categorized into six groups based on BMI: underweight (< 18.5 kg/m2), normal (18.5 to < 23 kg/m2), overweight (23 to < 25 kg/m2), mildly obese (25 to < 28 kg/m2), moderately obese (28 to < 30 kg/m2), and ...
Tópico(s): Nutrition and Health in Aging
2018 - Springer Science+Business Media | Gastric Cancer
Seon Sook Lee, Hyunjin Kim, Dae Kyung Sohn, Joo Beom Eom, Young Seok Seo, Hong Man Yoon, Yongdoo Choi,
Accurate identification of tumor sites and boundaries is of paramount importance during minimally invasive surgery. Although laparoscopic resection is being increasingly and widely performed for early gastric and colorectal cancers, the detection of tumors located inside the stomach and intestine is difficult owing to the lack of tactile sensation. Here, we propose the application of an indocyanine green (ICG)-loaded alginate hydrogel system as a fluorescence surgical marker for precise laparoscopic ...
Tópico(s): Cancer Research and Treatments
2020 - AME Publishing Company | Quantitative Imaging in Medicine and Surgery
Byung-Suk Chung, Zhang Hong-man, Min‐Ho Choi, Deogkyu Jeon, Shunyu Li, Mejeong Lee, Sung‐Tae Hong,
We investigated the induction of resistance to Clonorchis sinensis infection by prior infection in rat and hamster models. Animals were challenged with C. sinensis metacercariae, then treated with praziquantel and reinfected. Worm recovery rate in reinfected animals was used to estimate resistance to reinfection. The determined resistance rates to reinfection in rats and hamsters were 97.7% and 10.3%, respectively. In rats, cure from the primary infection of C. sinensis increased resistant to reinfection, ...
Tópico(s): Parasite Biology and Host Interactions
2004 - Korean Society for Parasitology | Korean Journal of Parasitology
Myong Cheol Lim, Suk‐Joon Chang, Boram Park, Heon Jong Yoo, Chong Woo Yoo, Byung Ho Nam, Sang‐Yoon Park, Sang‐Soo Seo, Sokbom Kang, Jung Yeon Yun, Dae-Soon Cho, Sun Ho Kim, Tae Sung Kim, Sung Sil Park, Dong Woon Lee, Sung Chan Park, Hyeong Min Park, Sung‐Sik Han, Seong Hoon Kim, Hee Chul Yang, Moon Soo Kim, Jong Mog Lee, Bang Wool Eom, Young‐Il Kim, Hong Man Yoon, Il Ju Choi, Sung Han Kim, Jae Young Joung, Ho Kyung Seo, Jung Nam Joo, Yong Jung Song, Sae Hyun Park, Dae Chul Jung, Min Jung Kim, Ji Won Park, Seung‐Yong Jeong, Young Ho Yun, Sohee Park, Robert E. Bristow,
Importance Ovarian cancer has the highest mortality rate among gynecologic malignant tumors. Data are lacking on the survival benefit of hyperthermic intraperitoneal chemotherapy (HIPEC) in women with ovarian cancer who underwent primary or interval cytoreductive surgery. Objective To assess the clinical benefit of HIPEC after primary or interval maximal cytoreductive surgery in women with stage III or IV primary advanced ovarian cancer. Design, Setting, and Participants In this single-blind randomized clinical ...
Tópico(s): Uterine Myomas and Treatments
2022 - American Medical Association | JAMA Surgery
Hongrae Kim, Sunhye Lee, Hyunjin Kim, Hee Jin Chang, Yongdoo Choi, Hong Man Yoon, Myeong‐Cherl Kook, So‐Youn Jung, Youngmi Kwon, Juehyung Kang, Hongki Yoo, Incheon Song, Seungrag Lee, Dae Kyung Sohn,
With the development of advanced and minimally invasive surgical techniques, and in view of the functional and cosmetic aspects, the need for rapid and accurate diagnosis during surgery is increasing. This study was conducted to develop a tissue diagnosis method using confocal microscopy after simple tissue staining that does not require freezing and slicing. At present, fluorescence staining with confocal microscopy is not generalized for real-time diagnosis during surgery. In this paper, we propose ...
Tópico(s): Nanoplatforms for cancer theranostics
2019 - Wiley | Microscopy Research and Technique
Jun Ho Lee, Il Ju Choi, Hye Seung Han, Young–Woo Kim, Keun Won Ryu, Hong Man Yoon, Bang Wool Eom, Chan Gyoo Kim, Jong Yeul Lee, Soo‐Jeong Cho, Young‐Il Kim, Byung‐Ho Nam, Myeong‐Cherl Kook,
Tópico(s): Gastrointestinal Tumor Research and Treatment
2014 - Springer Science+Business Media | Annals of Surgical Oncology
Sang Soo Eom, Wonyoung Choi, Bang Wool Eom, Sin Hye Park, Soo Jin Kim, Young‐Il Kim, Hong Man Yoon, Jong Yeul Lee, Chan Gyoo Kim, Hark Kyun Kim, Myeong‐Cherl Kook, Il Ju Choi, Young–Woo Kim, Young Iee Park, Keun Won Ryu,
Countries differ in their treatment expertise and research results regarding gastric cancer; hence, treatment guidelines are diverse based on evidence and medical situations. A comprehensive and comparative review of each country's guidelines is imperative to understand the similarities and differences among countries. We reviewed and compared five gastric cancer treatment guidelines in terms of endoscopic, surgical, perioperative, and palliative systemic treatment based on evidence levels and recommendation ...
Tópico(s): Colorectal and Anal Carcinomas
2022 - | Journal of the Korean Gastric Cancer Association
Young‐Il Kim, Myeong‐Cherl Kook, Jee Eun Choi, Jong Yeul Lee, Chan Gyoo Kim, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu, Young–Woo Kim, Il Ju Choi,
Purpose:The guidelines for pathological evaluation of early gastric cancer (EGC) recommend wider section intervals for surgical specimens (5-7 mm) than those for endoscopically resected specimens (2-3 mm).Studies in surgically resected EGC specimens showed not negligible lymph node metastasis risks in EGCs meeting the expanded criteria for endoscopic submucosal dissection (ESD).Materials and Methods: This retrospective study included 401 EGC lesions with an endoscopic size of ≤ 30 mm detected in 386 patients. ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2020 - | Journal of the Korean Gastric Cancer Association
Young‐Il Kim, Young–Woo Kim, Il Ju Choi, Chan Gyoo Kim, Jong Lee, Soo‐Jeong Cho, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu, Myeong‐Cherl Kook,
Background and study aim: Endoscopic resection for early gastric cancers that meet the expanded indication is considered to be an investigational treatment. The study aim was to evaluate long-term outcomes of endoscopic resection compared with surgery for early gastric cancers meeting the expanded indication. Methods: We retrospectively reviewed data from patients who underwent endoscopic resection or surgery for gastric cancers meeting the expanded indication between 2001 and 2009. Overall survival rate ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2015 - Thieme Medical Publishers (Germany) | Endoscopy
Heewon Kwak, Il Ju Choi, Chan Gyoo Kim, Jong Yeul Lee, Soo‐Jeong Cho, Bang Wool Eom, Hong Man Yoon, Jungnam Joo, Keun Won Ryu, Young–Woo Kim,
AIM:To evaluate whether individuals with gastric cancer (GC) are diagnosed earlier if they have firstdegree relatives with GC. METHODS:A total of 4282 patients diagnosed with GC at National Cancer Center Hospital from 2002 to 2012 were enrolled in this retrospective study.We classified the patients according to presence or absence of first-degree family history of GC and compared age at diagnosis and clinicopathologic characteristics.In addition, we further classified patients according to specific ...
Tópico(s): Childhood Cancer Survivors' Quality of Life
2015 - Baishideng Publishing Group | World Journal of Gastroenterology
Jung Hwan Lee, Boram Park, Jungnam Joo, Young‐Il Kim, Chan Gyoo Kim, Jong Yeul Lee, Il Ju Choi, Hong Man Yoon, Bang Wool Eom, Keun Won Ryu, Young–Woo Kim, Soo‐Jeong Cho,
16 Background: Although excess body weight has been known to be an important risk factor for mortality from many cancers including colorectal, endometrial and breast cancers, the prognosis of gastric cancer (GC) in obese patients seems controversial. Methods: We aimed to evaluate the association between body mass index (BMI) and mortality in GC in a large cohort. A single institute cohort of 7,765 GC patients undergoing curative gastrectomy between October 2000 and June 2016 were categorized into ...
Tópico(s): Metastasis and carcinoma case studies
2018 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Young–Woo Kim, Jae-Moon Bae, Young Kyu Park, Han‐Kwang Yang, Wansik Yu, Jeong Hwan Yook, Sung Hoon Noh, Mira Han, Keun Won Ryu, Tae Sung Sohn, Hyuk‐Joon Lee, Oh Kyoung Kwon, Seung Yeob Ryu, Jun-Ho Lee, Sung Hoon Kim, Hong Man Yoon, Bang Wool Eom, Min Gew Choi, Beom Su Kim, Oh Jeong, Yun‐Suhk Suh, Moon‐Won Yoo, In‐Seob Lee, Mi Ran Jung, Ji Yeong An, Hyoung‐Il Kim, Young‐Sook Kim, Hannah Yang, Byung‐Ho Nam,
Importance Acute isovolemic anemia occurs when blood loss is replaced with fluid. It is often observed after surgery and negatively influences short-term and long-term outcomes. Objective To evaluate the efficacy and safety of ferric carboxymaltose to treat acute isovolemic anemia following gastrectomy. Design, Setting, and Participants The FAIRY trial was a patient-blinded, randomized, phase 3, placebo-controlled, 12-week study conducted between February 4, 2013, and December 15, 2015, in 7 centers across ...
Tópico(s): Hemoglobinopathies and Related Disorders
2017 - American Medical Association | JAMA
Ji Yeon Park, Keun Won Ryu, Daniel Reim, Bang Wool Eom, Hong Man Yoon, Ji Yoon Rho, Il Ju Choi, Young–Woo Kim,
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2015 - Springer Science+Business Media | World Journal of Surgery
Shiela S. Macalindong, Kwang Hee Kim, Byung‐Ho Nam, Keun Won Ryu, Norihito Kubo, Ja Yeon Kim, Bang Wool Eom, Hong Man Yoon, Myeong‐Cherl Kook, Il Ju Choi, Young–Woo Kim,
Greater lymph node retrieval in gastric cancer improves staging accuracy and may improve survival from increased clearance of nodal micrometastasis. This retrospective cohort study investigated if more lymph nodes removed in gastric cancer increases survival and if such effect is stage-specific due to differential risks of nodal micrometastasis and systemic disease. The prospectively collected database of curatively resected gastric cancer patients in National Cancer Center, South Korea between ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2018 - BioMed Central | BMC Cancer
Mi Ah Han, Young–Woo Kim, Il Ju Choi, Myueng Guen Oh, Chan Gyoo Kim, Jong Yeul Lee, Soo‐Jeong Cho, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu,
Abstract Background: Smoking and drinking alcohol are major risk factors for cancer development, and we investigated their effects on gastric cancer prognosis following initial resection. Methods: Data from male patients with stage III–IV gastric adenocarcinoma who underwent surgery between 2001 and 2006 were retrospectively reviewed. Patients were followed up until 2011. Kaplan–Meier plots and Cox proportional hazards regressions were applied for survival rates. Results: Among 238 patients, 151 ( ...
Tópico(s): Cancer, Lipids, and Metabolism
2013 - American Association for Cancer Research | Cancer Epidemiology Biomarkers & Prevention
Jung Hwan Lee, Chan Gyoo Kim, Young–Woo Kim, Il Ju Choi, Jong Yeul Lee, Soo‐Jeong Cho, Young‐Il Kim, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu,
Purpose: To report our experience of endoscopic botulinum toxin injection in patients who experienced severe delayed gastric emptying after pylorus-preserving gastrectomy (PPG). Materials and Methods:We reviewed the medical records of 6 patients who received the botulinum toxin injection.They presented with severe delayed gastric emptying in the early postoperative period.Endoscopic botulinum toxin was administered as 4 injections of 25-50 IU into each of the 4 quadrants of the prepyloric area.Results: ...
Tópico(s): Gastroesophageal reflux and treatments
2017 - | Journal of the Korean Gastric Cancer Association
Jung‐Woo Woo, Keun Won Ryu, Ji Yeon Park, Bang Wool Eom, Mi Jung Kim, Hong Man Yoon, Sook Ryun Park, Myeong‐Cherl Kook, Il Ju Choi, Young–Woo Kim, Young‐Iee Park,
Tópico(s): Metastasis and carcinoma case studies
2013 - Springer Science+Business Media | World Journal of Surgery
Hong-Man Cho, Kyujung Lee, Woongbae Min, Yong Suk Choi, Hyun Suk Lee, Hyoung Jin Mun, Hye Young Shim, Da Geon Lee, Mi Joung Yoo,
Survival and Functional Outcomes after Hip Fracture among Nursing Home ResidentsFollowing the implementation of a long-term care insurance system for the elderly in Korea, many nursing homes have been established and many more patients than ever before have been living at nursing homes.Despite the fact that this is a high-risk group vulnerable to hip fractures, no study has yet been conducted in Korea on hip fracture incidence rates and prognoses among patients residing at nursing homes.We recently ...
Tópico(s): Pelvic and Acetabular Injuries
2016 - Korean Academy of Medical Sciences | Journal of Korean Medical Science
Young‐Il Kim, Chan Gyoo Kim, Jong Yeul Lee, Il Ju Choi, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu, Young‐Woo Kim,
A thread-fix stent entails long hospitalization and patient discomfort. We aimed to evaluate the efficacy of a novel stent with silicone-covered outer double layers without external fixation (Beta stent) for anastomotic leakage after total or proximal gastrectomy. The outcomes were compared between gastric cancer patients who underwent stent placement using a thread-fix stent between 2014 and 2015 (Thread-Fix Group) and those who received a Beta stent in the succeeding period until October 2018 (Beta ...
Tópico(s): Metastasis and carcinoma case studies
2021 - Multidisciplinary Digital Publishing Institute | Cancers
Zhang Hong-man, Byung-Suk Chung, Shunyu Li, Min-Ho Choi, Sung‐Tae Hong,
Tópico(s): Intestinal Malrotation and Obstruction Disorders
2008 - Springer Science+Business Media | Parasitology Research
Zhang Hong-man, Byung-Suk Chung, Shunyu Li, Min‐Ho Choi, Sung‐Tae Hong,
Rats develop strong resistance to re-infection and super-infection by Clonorchis sinensis. The present study investigated the antibodies present in the sera and bile juice of rats that were primary infected and re-infected with C. sinensis. The serum level of specific IgG antibodies, which were elevated 2 wk of the primary infection, peaked at 4 wk and subsequently remained unchanged even during re-infection. The total IgE level in serum increased slowly from 388 ng / ml to 3,426 ng / ml beginning 2 ...
Tópico(s): Trace Elements in Health
2008 - Korean Society for Parasitology | Korean Journal of Parasitology
Il Ju Choi, Young–Woo Kim, Hee Seok Lee, Keun Won Ryu, Hong Man Yoon, Bang Wool Eom, Chan Gyoo Kim, Jong Yeul Lee, Soo‐Jeong Cho, Byung‐Ho Nam,
BACKGROUND Gastrectomy is known as one of the risk factors for TB. However, there is no study about the association between TB development and gastrectomy performed in patients with early gastric cancer (EGC). This study evaluated conventional risk factors, including gastrectomy, associated with TB development in patients with EGC. METHODS A retrospective cohort study was performed using the database of the Center for Gastric Cancer of the National Cancer Center, Korea. The patients with EGC whose ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2015 - Elsevier BV | CHEST Journal
Daniel Reim, Alexander Novotny, Bang Wool Eom, Yunjin Park, Hong Man Yoon, II Ju Choi, Young–Woo Kim, Byung Ho Nam, Keun Won Ryu,
Several nomograms for survival prediction after curative gastric cancer surgery have been published over the recent years. Previous validation studies failed to prove applicability of Eastern Asian nomograms in Western patients. Here we present data on a validation analysis of a newly developed Korean nomogram in a German patient cohort. Among a total of 2771 patients having been treated in the Department of Surgery of the Technische Universitaet Muenchen from 1982 to 2008, 908 patients were eligible ...
Tópico(s): Esophageal Cancer Research and Treatment
2015 - Wolters Kluwer | Medicine
Bang Wool Eom, Jeongseon Kim, Deok Hee Kim, Young‐Il Kim, Hong Man Yoon, Soo‐Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi, Young–Woo Kim, Byung‐Ho Nam, Keun Won Ryu,
This study was aimed at evaluating the food intake and nutritional status of patients who underwent gastrectomy for gastric cancer based on a large-scale gastric cancer cohort.An observational prospective cohort study for gastric cancer has been conducted since 2010. From the cohort data, we selected the data for patients who completed at least 2 days of 3-day diet diaries and who underwent subtotal gastrectomy (STG) or total gastrectomy (TG). As a control group, patients who underwent endoscopic ...
Tópico(s): Nutrition and Health in Aging
2017 - Karger Publishers | Digestive Surgery
Yoon Jung Oh, Deok Hee Kim, Won Ho Han, Bang Wool Eom, Young‐Il Kim, Hong Man Yoon, Jong Yeul Lee, Chan Gyoo Kim, Myeong‐Cherl Kook, Il Ju Choi, Young–Woo Kim, Keun Won Ryu,
Lymphatic invasion (LI) is a potent risk factor for lymph node metastasis (LNM) in early gastric cancer (EGC) after endoscopic submucosal dissection (ESD). However, there are also other risk factors for LNM. Hence, to identify the need for additional surgery in some case of EGC without LI, the present study aimed to identify the risk factors for LNM in patients with EGC without LI.Data from 2284 patients diagnosed with EGC who underwent curative surgery at National Cancer Center in Korea from January ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2021 - Elsevier BV | European Journal of Surgical Oncology
Young–Woo Kim, Jungnam Joo, Hong Man Yoon, Bang Wool Eom, Keun Won Ryu, Il Ju Choi, Myeong‐Cherl Kook, Christoph Schuhmacher, Joerg Ruediger Siewert, Daniel Reim,
Several retrospective analyses on patients who underwent gastric cancer (GC) surgery revealed different survival outcomes between Eastern (Korean, Japanese) and Western (USA, Europe) countries due to potential ethnical and biological differences. This study investigates treatment outcomes between specialized institution for GC in Korea and Germany. The prospectively documented databases of the Gastric Cancer Center of the National Cancer Center, Korea (NCCK) and the Department of Surgery of the Technische ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2016 - Wolters Kluwer | Medicine