Yung‐Keun Kwon, Sun Shim Choi, Kwang‐Hyun Cho,
Abstract Background A number of studies on biological networks have been carried out to unravel the topological characteristics that can explain the functional importance of network nodes. For instance, connectivity, clustering coefficient, and shortest path length were previously proposed for this purpose. However, there is still a pressing need to investigate another topological measure that can better describe the functional importance of network nodes. In this respect, we considered a feedback ...
Tópico(s): Protein Structure and Dynamics
2007 - BioMed Central | BMC Bioinformatics
Hye Kyung Jeon, Noh Pal Jung, In Ho Choi, Yung Keun Oh, Hyung Chol Shin, Byoung Joo Gwag,
We investigated the effects of substance P (SP) on nitric oxide (NO) synthase activity in macrophages by measuring the production of nitrite and the expression of inducible NO synthase (iNOS) mRNA and protein. In LPS-activated macrophages, SP stimulated NO production in time and concentration dependent manners. These SP effects were blocked by a specific NK-1 receptor antagonist. Furthermore, SP stimulation increased the levels of both iNOS mRNA and iNOS protein. These results demonstrate that SP can ...
Tópico(s): Receptor Mechanisms and Signaling
1999 - Elsevier BV | Immunopharmacology
Ki-Choon Choi, Nam-Chul Jo, Min‐Woong Jung, Kyung-Dong Lee, Jong Geun Kim, Young-Chul Lim, Won Ho Kim, Yung-Keun Oh, Jin-Hyuk Choi, Cheon-Man Kim, Du-Keun Jung, Jong-Man Choi,
본 시험은 수확시기가 옥수수 원형 곤포사일리지의 품질에 미치는 영향을 구명하기 위하여 2009년부터 2010년까지 국립축산과학원에서 수행되었다. 옥수수 사일리지 전용 품종인 광평옥을 이용하여 숙기별 3회(유숙기, 황숙기 및 완숙기)에 걸쳐 수확을 하여 사일리지로 조제하였다. 숙기가 진행됨에 따라 옥수수 원형 곤포사일리지의 조단백질과 TDN 함량은 감소하는 경향을 보였으나 섬유소인 NDF 및 ADF 함량은 증가하였다. 그리고 숙기별 in vitro 건물 소화율은 비슷하였다. 숙기별 사일리지의 pH는 3.8~4.0을 유지하였으며, 숙기별 차이는 크지 않았다. 또한 생육이 진행됨에 따라 초산 함량은 감소되었으나 젖산 함량은 증가되었다. 그리고 품질등급은 완숙기> 황숙기> 유숙기 순으로 나타났다. 이상의 결과를 종합하여 볼 때 양질의 옥수수 원형 곤포사일리지 제조를 위해서는 황숙기에 수확하여 사일리지를 만드는 것이 옥수수 사일리지 발효를 향상시킬 수 있다. This study was carried ...
Tópico(s): Nutrition, Health and Food Behavior
2011 - | Journal of The Korean Society of Grassland and Forage Science
Mi Hyun Kim, Kyoungsook Park, Byoung Joo Gwag, Noh‐Pal Jung, Yung Keun Oh, Hyung‐Cheul Shin, Inho Choi,
Cellular and biochemical responses of the pectoral muscle to variation in seasonal activity were studied in the bat, Murina leucogaster ognevi. We collected bats in mid-hibernation (February), end-hibernation (April), and mid-summer (August) to track major activity periods in their annual cycle. Our findings indicated that myofiber cross-sectional area decreased to 68% between mid- and end-hibernation, but returned to the winter level in mid-summer. Total soluble protein and total RNA concentrations ...
Tópico(s): Mitochondrial Function and Pathology
2000 - Elsevier BV | Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
Sung-Soon Choi, Yung‐Keun Kwon, Byung Ro Moon,
The properties of symmetric fitness functions are investigated. We show that the search spaces obtained from symmetric functions have the zero-correlation structures between fitness and distance. It is also proven that symmetric functions induce a class of the hardest problems in terms of the epistasis variance and its variants. These analyses suggest that the existing quantitative measures cannot discriminate among symmetric functions, which reveals critical limitations of the measures. To take ...
Tópico(s): Optimization and Search Problems
2007 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Evolutionary Computation
Inho Choi, Yeonmi Cho, Yung Keun Oh, Noh‐Pal Jung, Hyung‐Cheul Shin,
Body temperatures of winter‐resident Korean bats typically range from 10° to 40°C between August and September and from 3° to 15°C between January and April. To learn how behavior and the motor systems of heterothermic bats respond to this body‐temperature variation, we examined whole‐organism performance and the temperature‐dependence of contractile properties of flight muscle in Murina leucogaster ognevi. In winter and midspring, the lowest limits of body temperature were 8°C for biting and crawling, ...
Tópico(s): Thermoregulation and physiological responses
1998 - University of Chicago Press | Physiological Zoology
Chung‐Kil Won, Byung-Ki Kim, Noh‐Pal Jung, Yung-Keun Oh, Inho Choi, Han-Woo Park, Hyung-Cheul Shin,
THE effects of acute lowering of body temperature on afferent sensory transmission to the primary somatosensory cortex were determined quantitatively in anaesthetized rats and hamsters. Rats showed no change in afferent sensory transmission until 27°C, but dramatic suppression between 26°C and 22°C, reaching 100% inhibition at 21°C. Hamsters exhibited gradual suppression of sensory transmission from 34°C to 18°C, reaching 95% inhibition at 18°C. Differential effects were also observed during rewarming ...
Tópico(s): Circadian rhythm and melatonin
1996 - Lippincott Williams & Wilkins | Neuroreport
Inho Choi, Yung Keun Oh, Noh‐Pal Jung, Byoung Joo Gwag, Hyung‐Cheul Shin,
The winter‐resident Korean bats, Murina leucogaster ognevi, show a circadian cycle of thermoregulation and locomotion in summer, as do other bat species in temperate regions. They are most active between dusk and dawn with body temperature (Tb) of 35–40°C, and are usually torpid in their roost sites for the rest of day with their Tb close to ambient temperature (Ta) of around 15°C. The present study was conducted to determine thermogenic and thermolabile properties of the heterothermic bats that would ...
Tópico(s): Adipose Tissue and Metabolism
1998 - Taylor & Francis | Korean Journal of Biological Sciences
Inho Choi, Youn Sun Lee, Yung Keun Oh, Noh‐Pal Jung, Byoung Joo Gwag, Hyung‐Cheul Shin,
Temperate‐resident bats exhibit a circadian cycle of torpor and arousal in summer. The physiological role and selective advantage of torpor as an energy saving mechanism have been received much attention by hibernation biologists. However, despite the significance of the recovering euthermic function, the arousal process and mechanism in these animals have been poorly addressed. In this study, we investigated thermogenic and motor activities of a local bat species Marina leucogaster during arousal ...
Tópico(s): Physiological and biochemical adaptations
2001 - Taylor & Francis | Korean Journal of Biological Sciences
Yung Keun Oh, Kum Duck Choi, Hyuck Bang, Man Soo Pak,
Tópico(s): Effects and risks of endocrine disrupting chemicals
1968 - Yonsei University College of Medicine | Yonsei Medical Journal
Kum Duck Choi, Yung Keun Oh, Dal Uck Park, Kyu Soon Rhim, Tong Hun Cho,
Tópico(s): Microfluidic and Bio-sensing Technologies
1966 - Yonsei University College of Medicine | Yonsei Medical Journal
Yung-Keun Oh, Byung-Sik Ahn, In-Ho Choi, Noh‐Pal Jung, Hyung-Cheul Shin, Byoung-Ju Kwak,
Fertilization pattern of north temperate bats is known to be unique for their sperm storage in the female reproductive tract during hibernation (e.g. Korean greater horseshoe bats). They copulate in fall but their ejaculated spermatozoa survive until the next spring. In another words they can persist to survive during long hibernation under the cold condition and are to be fertilized with the ovum ovulated in the next spring, so called delayed fertilization. The present study was designed to observe ...
Tópico(s): Reproductive Biology and Fertility
1999 - Springer Nature | Han-guk hyeonmigyeong hakoeji/Applied microscopy
Yung Keun Oh, Soo Yun Pak, Tai Su Kwon, Kum Duck Choi,
Tópico(s): Mast cells and histamine
1964 - Yonsei University College of Medicine | Yonsei Medical Journal
Yung Keun Oh, Soo Yun Pak, Tai Sun Shin, Kum Duck Choi,
Tópico(s): Mast cells and histamine
1962 - Yonsei University College of Medicine | Yonsei Medical Journal
Kum Duck Choi, Seung Bong Ahn, Yung Keun Oh, Kyu Soon Rhim, Byong Yull Moon,
Tópico(s): Analytical Chemistry and Chromatography
1967 - Yonsei University College of Medicine | Yonsei Medical Journal
Sun Ah Park, Yung‐Keun Kwon, Hyeong Jun Kim, Tae Eun Kim, Yoon‐Jeong Kim, Jong Hun Kim, Sang Won Seo, Duk L. Na, Jeong Yeon Kim, Seong Hye Choi,
The concentrations and combined ratios of beta amyloid 1-42 (A β42) and tau proteins are widely used as Alzheimer's disease (AD) biomarkers in cerebrospinal fluid (CSF). However,due to large variability in measurements and poor prediction of clinical courses, further applications of these biomarkers are limited. We conducted this study to develop novel biomarkers that supplement the shortage of known AD biomarkers. High throughout proteomic analysis was performed in mild sporadic AD patients who demonstrated ...
Tópico(s): Dementia and Cognitive Impairment Research
2014 - Wiley | Alzheimer s & Dementia