CHARLES BAKER, WALTER MÉVILLE., EDWARD LINCOLN, WILLIAM E. HAIGH., FROM OUR OWN CORRESPONDENT., FROM OUR CORRESPONDENT., A. V. DICEY., FROM OUR SPECIAL CORRESPONDENT., JOSEPH FELS., LEX., JOHN INGLIS, R. H. READE, FROM OUR PARLIAMENTARY CORRESPONDENT., FROM OUR DUBLIN CORRESPONDENT., Our Paris Correspondent, FROM A CORRESPONDENT., WYNDHAM A. BEWES., AILWYN FELLOWES., BY A CORRESPONDENT., FROM OUR SWISS CORRESPONDENT., FRANK MORRIS., A. W. FINDLAY.,
... Smith, M. Félix Ziem., Mr. John Holroyd., M. Christian Lundeberg., Canon J. R. T. Eaton., Mr. Holt Hallett.. ...
1911 - Gale Group | TDA
David O. Dias, Hoseok Kim, Daniel Holl, Beata Werne Solnestam, Joakim Lundeberg, Marie Carlén, Christian Göritz, Jonas Frisén,
CNS injury often severs axons. Scar tissue that forms locally at the lesion site is thought to block axonal regeneration, resulting in permanent functional deficits. We report that inhibiting the generation of progeny by a subclass of pericytes led to decreased fibrosis and extracellular matrix deposition after spinal cord injury in mice. Regeneration of raphespinal and corticospinal tract axons was enhanced and sensorimotor function recovery improved following spinal cord injury in animals with ...
Tópico(s): Axon Guidance and Neuronal Signaling
2018 - Cell Press | Cell
Irene Mittermann, Gustav Wikberg, Catharina Johansson, Christian Lupinek, Lena Lundeberg, Reto Crameri, Rudolf Valenta, Annika Scheynius,
Background Atopic dermatitis (AD) is a complex chronic inflammatory disease where allergens can act as specific triggering factors. Aim To characterize the specificities of IgE-reactivity in patients with AD to a broad panel of exogenous allergens including microbial and human antigens. Methodology Adult patients with AD were grouped according to the SCORAD index, into severe (n = 53) and moderate AD (n = 126). As controls 43 patients were included with seborrhoeic eczema and 97 individuals without history ...
Tópico(s): Contact Dermatitis and Allergies
2016 - Public Library of Science | PLoS ONE
Jacob Odeberg, Øystein Røsok, Guðmundur H. Guðmundsson, Afshin Ahmadian, Leyla Roshani, Cecilia Williams, Catharina Larsson, Fredrik Pontén, Mathias Uhlén, Hans‐Christian Åsheim, Joakim Lundeberg,
A 3-kb-long cDNA encoding aKrüppel-like human zinc finger protein was isolated and mapped to chromosome 9q22–q31. The ZNF189 gene encodes a protein with 16 zinc fingers at its C-terminus and belongs to theKrüppel-associated box (KRAB)-containing group of zinc finger proteins. Four differently spliced cDNA transcripts, differing at the 5′ coding region where a KRAB A repressor domain is encoded, were isolated. In addition, Northern blot analysis indicates the presence of two additional unidentified ...
Tópico(s): Kruppel-like factors research
1998 - Elsevier BV | Genomics
Øystein Røsok, Florence Pédeutour, Jacob Odeberg, Joakim Lundeberg, Hans‐Christian Aasheim,
Here we report the characterization of a human mRNA encoding a novel protein denoted C1orf9 (chromosome 1 open reading frame 9). The cDNA sequence, derived from a testis cDNA library, contains 5700 bp which encodes an open reading frame of 1254 amino acids. The deduced protein contains a putative N-terminal signal peptide and one putative transmembrane region, indicating membrane localization. No significant homology was found with known characterized proteins. However, a 150 amino acid region has ...
Tópico(s): Genomics and Chromatin Dynamics
2000 - Elsevier BV | Biochemical and Biophysical Research Communications
Christian Natanaelsson, Mattias Oskarsson, Helen Angleby, Joakim Lundeberg, Ewen F. Kirkness, Peter Savolainen,
Abstract Background Population genetic studies of dogs have so far mainly been based on analysis of mitochondrial DNA, describing only the history of female dogs. To get a picture of the male history, as well as a second independent marker, there is a need for studies of biallelic Y-chromosome polymorphisms. However, there are no biallelic polymorphisms reported, and only 3200 bp of non-repetitive dog Y-chromosome sequence deposited in GenBank, necessitating the identification of dog Y chromosome ...
Tópico(s): Zoonotic diseases and public health
2006 - BioMed Central | BMC Genomic Data
Patrik L. Ståhl, Jesper Gantelius, Christian Natanaelsson, Afshin Ahmadian, Helene Andersson Svahn, Joakim Lundeberg,
In this paper we describe a method that uses the nearly covalent strength biotin–streptavidin interaction to attach a paramagnetic bead of micrometer size to a DNA molecule of nanometer size, scaling up the spatial size of a query DNA strand by a factor of 1000, making it visible to the human eye. The use of magnetic principles enables rapid binding and washing of detector beads, facilitating a readout of amplified DNA sequences in a few minutes. Here we exemplify the method on mitochondrial DNA ...
Tópico(s): Gene expression and cancer classification
2007 - Elsevier BV | Genomics
Yajing Song, Christian G. Giske, Patrik Gille-Johnson, Olof Emanuelsson, Joakim Lundeberg, Péter Gyarmati,
Sepsis is a severe medical condition characterized by a systemic inflammatory response of the body caused by pathogenic microorganisms in the bloodstream. Blood or plasma is typically used for diagnosis, both containing large amount of human DNA, greatly exceeding the DNA of microbial origin. In order to enrich bacterial DNA, we applied the C0t effect to reduce human DNA background: a model system was set up with human and Escherichia coli (E. coli) DNA to mimic the conditions of bloodstream infections; ...
Tópico(s): CRISPR and Genetic Engineering
2014 - Public Library of Science | PLoS ONE
Hagen B. Huttner, Olaf Bergmann, Mehran Salehpour, Áttila Rácz, Jemal Tatarishvili, Emma Lindgren, Tamás Csonka, László Csiba, Tibor Hortobágyi, Gábor Méhes, Elisabet Englund, Beata Werne Solnestam, Sofia Zdunek, Christian Scharenberg, Lena Ström, Patrik L. Ståhl, Bárður Sigurgeirsson, Andreas Dahl, Stefan Schwab, Göran Possnert, Samuel Bernard, Zaal Kokaia, Olle Lindvall, Joakim Lundeberg, Jonas Frisén,
It has been unclear whether ischemic stroke induces neurogenesis or neuronal DNA rearrangements in the human neocortex. Using immunohistochemistry; transcriptome, genome and ploidy analyses; and determination of nuclear bomb test-derived (14)C concentration in neuronal DNA, we found neither to be the case. A large proportion of cortical neurons displayed DNA fragmentation and DNA repair a short time after stroke, whereas neurons at chronic stages after stroke showed DNA integrity, demonstrating the ...
Tópico(s): Epigenetics and DNA Methylation
2014 - Nature Portfolio | Nature Neuroscience
Yafeng Zhu, Pär G. Engström, Christian Tellgren‐Roth, Charles Baudo, John C. Kennell, Sheng Sun, R. Blake Billmyre, Markus Schröder, Anna Andersson, Tina Holm, Benjamín Sigurgeirsson, Guangxi Wu, Sundar Ram Sankaranarayanan, Rahul Siddharthan, Kaustuv Sanyal, Joakim Lundeberg, Björn Nystedt, Teun Boekhout, Thomas L. Dawson, Joseph Heitman, Annika Scheynius, Janne Lehtiö,
Complete and accurate genome assembly and annotation is a crucial foundation for comparative and functional genomics. Despite this, few complete eukaryotic genomes are available, and genome annotation remains a major challenge. Here, we present a complete genome assembly of the skin commensal yeast Malassezia sympodialis and demonstrate how proteogenomics can substantially improve gene annotation. Through long-read DNA sequencing, we obtained a gap-free genome assembly for M. sympodialis (ATCC 42132), ...
Tópico(s): Fungal Biology and Applications
2017 - Oxford University Press | Nucleic Acids Research
Tanja C. Fischer, Petra Hartmann, Christoph Löser, Jochen Springer, Christian Peiser, Q. Thai Dinh, Axel Fischer, David A. Groneberg,
... 21) Google Scholar) and in allergic contact dermatitis (Lundeberg and Nordlind, 1999Lundeberg L. Nordlind K. Vasoactive intestinal ... Scopus (109) Google Scholar) or allergic contact dermatitis (Lundeberg and Nordlind, 1999Lundeberg L. Nordlind K. Vasoactive intestinal ... demonstration of VPAC2 immunoreactivity in allergic contact dermatitis (Lundeberg and Nordlind, 1999Lundeberg L. Nordlind K. Vasoactive intestinal ...
Tópico(s): Receptor Mechanisms and Signaling
2001 - Elsevier BV | Journal of Investigative Dermatology
... well as fatigue. Possibly the princess in Hans Christian Andersen's ‘The Princess and the Pea’ suffered ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2007 - SAGE Publishing | Acupuncture in Medicine
Mikael Björklund, Christian Natanaelsson, Amelie Eriksson Karlström, Yangyang Hao, Joakim Lundeberg,
DNA microarray technology has evolved dramatically in recent years, and is now a common tool in researchers' portfolios. The scope of the technique has expanded from small-scale studies to extensive studies such as classification of disease states. Technical knowledge regarding solid phase microarrays has also increased, and the results acquired today are more reliable than those obtained just a few years ago. Nevertheless, there are various aspects of microarray analysis that could be improved. ...
Tópico(s): Single-cell and spatial transcriptomics
2007 - Oxford University Press | Nucleic Acids Research
Joana P. Bernardes, Neha Mishra, Florian Tran, Thomas Bahmer, Lena Best, Johanna I. Blase, Dora Bordoni, Jeanette Franzenburg, Ulf Geisen, Jonathan Josephs‐Spaulding, Philipp Köhler, Axel Künstner, Elisa Rosati, Anna C. Aschenbrenner, Petra Bächer, Nathan Baran, Teide Jens Boysen, Burkhard Brandt, Niklas Bruse, Jonathan Dörr, Andreas Dräger, Gunnar Elke, David Ellinghaus, Julia Fischer, Michael Förster, André Franke, Sören Franzenburg, Norbert Frey, Anette Friedrichs, Janina Fuß, Andreas Glück, Jacob Hamm, Finn Hinrichsen, Marc P. Hoeppner, Simon Imm, Ralf Junker, Sina Kaiser, Ying H. Kan, Rainer Knoll, Christoph Lange, Georg Laue, Clemens Lier, Matthias Lindner, Γεώργιος Μαρίνος, Robert Markewitz, Jacob Nattermann, Rainer Noth, Peter Pickkers, Klaus F. Rabe, Alina Renz, Christoph Röcken, Jan Rupp, Annika Schaffarzyk, Alexander Scheffold, Jonas Schulte-Schrepping, Domagoj Schunk, Dirk Skowasch, Thomas Ulas, Klaus‐Peter Wandinger, Michael Wittig, Johannes Zimmermann, Hauke Busch, Bimba F. Hoyer, Christoph Kaleta, Jan Heyckendorf, Matthijs Kox, Jan Rybniker, Stefan Schreiber, Joachim L. Schultze, Philip Rosenstiel, Nicholas E. Banovich, Tushar Desai, Oliver Eickelberg, Muzlifa Haniffa, Péter Horváth, Jonathan A. Kropski, Robert Lafyatis, Joakim Lundeberg, Kerstin B. Meyer, Martijn C. Nawijn, Marko Nikolić, José Ordovas Montañes, Dana Pe’er, Purushothama Rao Tata, Emma L. Rawlins, Aviv Regev, Paul A. Reyfman, Christos Samakovlis, Joachim L. Schultze, Alex K. Shalek, Douglas P. Shepherd, Jason R. Spence, Sarah A. Teichmann, Fabian J. Theis, Alexander M. Tsankov, Maarten van den Berge, Michael von Papen, Jeffrey A. Whitsett, Laure‐Emmanuelle Zaragosi, Angel Angelov, Robert Bals, Alexander Bartholomäus, Anke Becker, Daniela Bezdan, Ezio Bonifacio, Peer Bork, Thomas Clavel, Maria Colme-Tatche, Andreas Diefenbach, Alexander Dilthey, Nicole Fischer, Konrad U. Förstner, Julia-Stefanie Frick, Julien Gagneur, Alexander Goesmann, Torsten Hain, Michael Hummel, Stefan Janssen, Jörn Kalinowski, René Kallies, Birte Kehr, Andreas Keller, Sarah Kim-Hellmuth, Christoph Klein, Oliver Kohlbacher, Jan O. Korbel, Ingo Kurth, Markus Landthaler, Yang Li, Kerstin U. Ludwig, Oliwia Makarewicz, Manja Marz, Alice C. McHardy, Christian Mertes, Markus M. Nöthen, Peter Nürnberg, Uwe Ohler, Stephan Ossowski, Jörg Overmann, Silke Peter, Klaus Pfeffer, Anna R. Poetsch, Alfred Pühler, Nikolaus Rajewsky, Markus Ralser, Olaf Rieß, Stephan Ripke, Ulisses Nunes da Rocha, Philip Rosenstiel, Antoine‐Emmanuel Saliba, Leif Erik Sander, Birgit Sawitzki, Philipp H. Schiffer, Eva C. Schulte, Joachim L. Schultze, Alexander Sczyrba, Oliver Stegle, Jens Stoye, Fabian J. Theis, Jörg Janne Vehreschild, Jörg Vogel, Max von Kleist, Andreas Walker, Jörn Walter, Dagmar Wieczorek, John Ziebuhr,
Temporal resolution of cellular features associated with a severe COVID-19 disease trajectory is needed for understanding skewed immune responses and defining predictors of outcome. Here, we performed a longitudinal multi-omics study using a two-center cohort of 14 patients. We analyzed the bulk transcriptome, bulk DNA methylome, and single-cell transcriptome (>358,000 cells, including BCR profiles) of peripheral blood samples harvested from up to 5 time points. Validation was performed in two independent ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2020 - Cell Press | Immunity
Christoph Muus, Malte D. Luecken, Gökcen Eraslan, Lisa Sikkema, Avinash Waghray, Graham Heimberg, Yoshihiko Kobayashi, Eeshit Dhaval Vaishnav, Ayshwarya Subramanian, Christopher S. Smillie, Karthik A. Jagadeesh, Thu Elizabeth Duong, Evgenij Fiškin, Elena Torlai Triglia, Meshal Ansari, Peiwen Cai, Brian Lin, Justin Buchanan, Sijia Chen, Jian Shu, Adam L. Haber, Hattie Chung, Daniel T. Montoro, Taylor Adams, Hananeh Aliee, Samuel J. Allon, Žaneta Andrusivová, Ilias Angelidis, Orr Ashenberg, Kevin Baßler, Christophe Bécavin, Inbal Benhar, Joseph Bergenstråhle, Ludvig Bergenstråhle, Liam Bolt, Emelie Braun, Linh T. Bui, Steven Callori, Mark Chaffin, Evgeny Chichelnitskiy, Joshua Chiou, Thomas M. Conlon, Michael S. Cuoco, Anna Cuomo, Marie Deprez, Grant Duclos, Denise Fine, David S. Fischer, Shila Ghazanfar, Astrid Gillich, Bruno Giotti, Joshua Gould, Minzhe Guo, Austin J. Gutierrez, Arun C. Habermann, Tyler Harvey, Peng He, Xiaomeng Hou, Lijuan Hu, Yan Hu, Alok Jaiswal, Lu Ji, Peiyong Jiang, Theodoros Kapellos, Christin S. Kuo, Ludvig Larsson, Michael Leney-Greene, Kyungtae Lim, Monika Litviňuková, Leif S. Ludwig, Soeren Lukassen, Wendy Luo, Henrike Maatz, Elo Madissoon, Lira Mamanova, Kasidet Manakongtreecheep, Sylvie Leroy, Christoph H. Mayr, Ian Mbano, Alexi McAdams, Ahmad N. Nabhan, Sarah K. Nyquist, Lolita Penland, Olivier Poirion, Sergio Poli, Cancan Qi, Rachel Queen, Daniel Reichart, Iván O. Rosas, Jonas C. Schupp, Conor Shea, Xingyi Shi, Rahul Sinha, Rene Sit, Kamil Slowikowski, Michal Slyper, Neal P. Smith, Alex Sountoulidis, Maximilian Strunz, Travis Sullivan, Dawei Sun, Carlos Talavera‐López, Peng Tan, Jessica Tantivit, Kyle J. Travaglini, Nathan R. Tucker, Katherine A. Vernon, Marc H. Wadsworth, Julia Waldman, Xiuting Wang, Ke Xu, Wenjun Yan, William Zhao, Carly G.K. Ziegler, Gail Deutsch, Jennifer Dutra, Kyle J. Gaulton, Jeanne Holden‐Wiltse, Heidie Huyck, Thomas J. Mariani, Ravi Misra, Cory Poole, Sebastian Preißl, Gloria Pryhuber, Lisa M. Rogers, Xin Sun, Allen Wang, Jeffrey A. Whitsett, Yan Xu, Jehan Alladina, Nicholas E. Banovich, Pascal Barbry, Jennifer Beane, Roby P. Bhattacharyya, Katharine E. Black, Alvis Brāzma, Joshua D. Campbell, Christina Schofield, Joseph Collin, Christian Conrad, Kitty de Jong, Tushar Desai, Diane Z. Ding, Oliver Eickelberg, Roland Eils, Patrick T. Ellinor, Alen Faiz, Christine S. Falk, Michael Farzan, Andrew Gellman, Gad Getz, Ian Glass, Anna Greka, Muzlifah Haniffa, Lida P. Hariri, Mark Hennon, Péter Horváth, Norbert Hübner, Deborah T. Hung, Heidie Huyck, William J. Janssen, Dejan Juric, Naftali Kaminski, M. Koenigshoff, Gerard H. Koppelman, Mark A. Krasnow, Jonathan A. Kropski, Malte Kühnemund, Robert Lafyatis, Majlinda Lako, Eric S. Lander, Haeock Lee, Marc E. Lenburg, Charles‐Hugo Marquette, Ross J. Metzger, Sten Linnarsson, Gang Liu, Y. M. Dennis Lo, Joakim Lundeberg, John C. Marioni, Sarah A. Mazzilli, Benjamin D. Medoff, Kerstin B. Meyer, Zhichao Miao, Alexander V. Misharin, Martijn C. Nawijn, Marko Nikolić, Michela Noseda, José Ordovás-Montañés, Gavin Y. Oudit, Dana Pe’er, Joseph E. Powell, Stephen R. Quake, Jayaraj Rajagopal, Purushothama Rao Tata, Emma L. Rawlins, Aviv Regev, Mary E. Reid, Paul A. Reyfman, Kimberly Rieger‐Christ, Mauricio Rojas, Orit Rozenblatt–Rosen, Kourosh Saeb‐Parsy, Christos Samakovlis, Joshua R. Sanes, Herbert B. Schiller, Joachim L. Schultze, Roland F. Schwarz, Ayellet V. Segrè, Max A. Seibold, Christine E. Seidman, J.G. Seidman, Alex K. Shalek, Douglas P. Shepherd, Rahul Sinha, Jason R. Spence, Avrum Spira, Xin Sun, Erik Sundström, Sarah A. Teichmann, Fabian J. Theis, Alexander M. Tsankov, Ludovic Vallier, Maarten van den Berge, Tave A. Van Zyl, Alexandra–Chloé Villani, Astrid Weins, Ramnik J. Xavier, Ali Önder Yildirim, Laure‐Emmanuelle Zaragosi, Darin Zerti, Hongbo Zhang, Kun Zhang, Xiaohui Zhang,
Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry, and their expression may shed light on viral tropism and impact across the body. We assessed the cell-type-specific expression of ACE2, TMPRSS2 and CTSL across 107 single-cell RNA-sequencing studies from different tissues. ACE2, TMPRSS2 and CTSL are coexpressed in specific subsets of respiratory epithelial cells in the nasal passages, ...
Tópico(s): Single-cell and spatial transcriptomics
2021 - Nature Portfolio | Nature Medicine
Joakim Lundeberg, Jacob Odeberg, Kazuhiro Sentani, Naohide Oue, Humihiro Kondo, Kazuya Kuraoka, Junichi Motoshita, Reiko Ito, Hiroshi Yokozaki, Wataru Yasui, Katsuo Morita, Takahiro Fujimori, Yuko Ono, Hideyuki Hiraishi, Kenta Yoshiura, Tadahito Shimada, Hitoshi Sugaya, Akira Terano, Athena P. Kourtis, Christian Ibegbu, Franco Scinicarrielo, Francis K. Lee, Johannes Stöve, Christina Gerlach, Klaus Huch, Klaus Peter Günther, Rolf Brenner, W. Puhl, Hanns-Peter Scharf, Tsuyoshi Nemoto, Shinya Terashima, Michihiko Kogure, Yutaka Hoshino, Takashi Kusakabe, Toshimitsu Suzuki, Mitsukazu Gotoh, Tove Andersson, Stina Boräng, Magnus Larsson, Valtteri Wirta, Anders Wennborg, Hiroki Tamura, Hiroyuki Sugihara, Masamichi Bamba, Tohru Tani, Masao Hosokawa, Masashi Kodama, Takanori Hattori,
2001 - Karger Publishers | Pathobiology
Joakim Lundeberg, Jacob Odeberg, Kazuhiro Sentani, Naohide Oue, Humihiro Kondo, Kazuya Kuraoka, Junichi Motoshita, Reiko Ito, Hiroshi Yokozaki, Wataru Yasui, Katsuo Morita, Takahiro Fujimori, Yuko Ono, Hideyuki Hiraishi, Kenta Yoshiura, Tadahito Shimada, Hitoshi Sugaya, Akira Terano, Athena P. Kourtis, Christian Ibegbu, Franco Scinicarrielo, Francis K. Lee, Johannes Stöve, Christina Gerlach, Klaus Huch, Klaus Peter Günther, Rolf E. Brenner, W. Puhl, Hanns-Peter Scharf, Tsuyoshi Nemoto, Shinya Terashima, Michihiko Kogure, Yutaka Hoshino, Takashi Kusakabe, Toshimitsu Suzuki, Mitsukazu Gotoh, Tove Andersson, Stina Boräng, Magnus Larsson, Valtteri Wirta, Anders Wennborg, Hiroki Tamura, Hiroyuki Sugihara, Masamichi Bamba, Tohru Tani, Masao Hosokawa, Masashi Kodama, Takanori Hattori,
2001 - Karger Publishers | Pathobiology
... Edited by Cameron C. Gullette and Olav K. Lundeberg. New York: Harper and Brothers, 1936. Cloth. Illustrated. ...
Tópico(s): Historical and Literary Analyses
1937 - Wiley | Modern Language Journal