Joanne Riebschleger, Shane Costello, Daniel L. Cavanaugh, Christine Grové,
A program evaluation examined mental health literacy levels and coping outcomes for youth (ages 10-16), before and at the end of their participation in a manualized, school-based mental health literacy program called Youth Education and Support (YES). Most of the youth reportedly had a parent or other family member with a mental health disorder such as depression, anxiety, and/or substance abuse. The mental health literacy levels of program participants from pre to post were evaluated with the developing ...
Tópico(s): Maternal Mental Health During Pregnancy and Postpartum
2019 - Frontiers Media | Frontiers in Psychiatry
Jamie Cavanaugh, Christine D. Jones, Genevieve Embree, Katy K. Tsai, Thomas Miller, Betsy Bryant Shilliday, Brooke McGuirt, Robin Roche, Michael Pignone, Darren A. DeWalt, Shana Ratner,
To define comorbidities including chronic obstructive pulmonary disease or asthma, heart failure, diabetes, hypertension, coronary artery disease, and depression, we required the condition to be listed either on the index hospitalization discharge summary or on the general problem list of the EHR; in addition, an appropriate medication to treat this condition had to be listed in the index hospitalization discharge summary. Cirrhosis and chronic kidney disease required only a mention of this condition ...
Tópico(s): Chronic Disease Management Strategies
2014 - Springer Science+Business Media | Journal of General Internal Medicine
Nicole M. Dudukovic, Jackie L. Gottshall, Patricia A. Cavanaugh, Christine T. Moody,
Memory retrieval has been shown to enhance the long-term retention of tested material; however, recent research suggests that limiting attention during retrieval can decrease the benefits of testing memory. The present study examined whether testing benefits are reduced in young adults with attention-deficit hyperactivity disorder (ADHD). College students with and without ADHD read three short prose passages, each followed by a free recall test, a restudy period or a distractor task. Two days later ...
Tópico(s): Neural and Behavioral Psychology Studies
2014 - Taylor & Francis | Memory
Joseph Cavanaugh, Stephen Jacquemin, Christine Junker,
The onset of the COVID-19 global pandemic affected higher education in a myriad of ways. One of the most notable effects however was the rapid and sudden transition of nearly all courses at most institutions to an online environment. And while there are a growing number of courses offered online already, this transition to nearly 100% remote education presented numerous challenges for instructors and students of face-to-face and hybrid style courses. Since student perceptions are closely tied to ...
Tópico(s): Innovative Teaching Methods
2022 - Springer Science+Business Media | Technology Knowledge and Learning
Joseph Cavanaugh, Stephen Jacquemin, Christine Junker,
Purpose This study aims to use self-reported publicly available student assessment data from the time period when there was an abrupt change in instructional method at the start of COVID-19 to assess potential for differences as a result of course delivery mode. Design/methodology/approach A general linear model using 837 student evaluations from 191 US public higher education institutions investigates the impact on student performance and how performance was related to a number of covariates, namely, ...
Tópico(s): Online Learning and Analytics
2022 - Emerald Publishing Limited | Quality Assurance in Education
Ellen J Cavanaugh, Jenna Richardson, Christine McCallum, Mark Wilhelm,
Identification of preclinical disability in middle-aged and older adults might allow early identification of and treatment for functional mobility deficits.This study aimed to determine which physical performance measures (PPMs) were effective in identifying preclinical disability in individuals at risk for future disability.CINHAL, PubMed, Scopus, and Web of Science databases were searched until September 2017 using key words.Two individuals screened peer-reviewed prospective longitudinal studies ...
Tópico(s): Balance, Gait, and Falls Prevention
2018 - Oxford University Press | Physical Therapy
Christine Bell, Kathleen Cavanaugh,
... SELF-DETERMINATION, GROUP ACCOMMODATION, AND THE BELFAST AGREEMENT Christine Bell* Kathleen Cavanaugh **
Tópico(s): Post-Soviet Geopolitical Dynamics
1998 - Fordham University School of Law | Fordham international law journal
R.K. Bhamra, Lois E. Bolcsak, Imran Ahmad, James J. Schupsky, Patricia J. Roberts, Rachel Stevens, Christopher Cavanaugh, Christine E. Swenson,
TLC ELL-12 is a liposomal formulation of the novel antineoplastic compound 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine (L-ET-18-OCH3). The purpose of these studies was to evaluate the activity and tissue distribution of L-ET-18-OCH3 when administered i.v. as TLC ELL-12 to rats bearing solid tumors. Growth-inhibitory activity of L-ET-18-OCH3 and TLC ELL-12 against methylnitrosourea (MNU)-induced tumors grown in vitro was evaluated. Female Buffalo rats were injected s.c. with transplantable ...
Tópico(s): Cancer therapeutics and mechanisms
2003 - Lippincott Williams & Wilkins | Anti-Cancer Drugs
Howard C. Smith, Caitlin K. Cavanaugh, Jennifer L. Friz, Christine S. Thompson, Jessica A. Saggers, Enrique L. Michelotti, Javier Garcia, Colin M. Tice,
A library of 35 cis-1-benzoyl-2-methyl-4-(phenylamino)-1,2,3,4-tetrahydroquinolines was prepared. The compounds bore various substitutuents on the benzoyl ring, at the 4-position of the phenylamino ring and at the 6-position of the tetrahydroquinoline ring. The compounds were assayed for their ability to cause expression of a reporter gene downstream of an ecdysone response element in a mammalian cell line engineered to express the ecdysone receptor from Aedes aegypti. In general, compounds with ...
Tópico(s): bioluminescence and chemiluminescence research
2003 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Jillian R. Cavanaugh, Kathleen Riley, Alexandra Jaffe, Christine Jourdan, Martha Sif Karrebæk, Amy L. Paugh,
This article offers an introduction to the methods being developed by scholars interested in studying food and language as interrelated phenomena. First, we explore a few of the intriguing parallels that have inspired a number of researchers to study food and language simultaneously. Then, we look at how the study of language led each of us to the study of food and consider if and how the methods we have used for this new enterprise differ from linguistic anthropological methods used to study other ...
Tópico(s): Linguistic Variation and Morphology
2014 - Wiley | Journal of Linguistic Anthropology
Charity Adedokun, Jane Tang, Christine Cavanaugh,
The changing demographic landscape in the United States and the need to achieve workforce diversity in nursing call for strategies designed to enhance graduation rates of minority nursing students. Simulation is an effective teaching-learning strategy in nursing programs; however, limited studies exist that examine the experiences of English-as-a-Second Language (ESL) nursing students in simulation environments.To explore the lived experiences of ESL Baccalaureate Prelicensure Nursing (BSN) students ...
Tópico(s): Interpreting and Communication in Healthcare
2022 - Elsevier BV | Journal of Professional Nursing
Catherine Paolucci, Sam Vancini, Richard T. Bex, Terence Cavanaugh, Christine Salama, Zandra de Araujo,
Use of learning analytics to improve educational outcomes is a growing area of research. While learning analytics research has been more prevalent in higher education contexts, this study presents findings from a qualitative metasynthesis of 47 research publications related to opportunities and challenges relevant to learning analytics design, implementation, and research at the PK-12 level. Our findings indicate that, while many see the educational benefits of learning analytics (e.g., more equitable ...
Tópico(s): Online Learning and Analytics
2024 - Elsevier BV | Heliyon
Alex Boomgarden, Gabriel Sagewalker, Aashaka Shah, Sarah D. Haider, Pramathini Patel, Heather E. Wheeler, Christine Dubowy, Daniel J. Cavanaugh,
Circadian clocks are found in nearly all organisms, from bacteria to mammals, and ensure that behavioral and physiological processes occur at optimal times of day and in the correct temporal order. It is becoming increasingly clear that chronic circadian misalignment (CCM), such as occurs in shift workers or as a result of aberrant sleeping and eating schedules common to modern society, has profound metabolic and cognitive consequences, but the proximate mechanisms connecting CCM with reduced organismal ...
Tópico(s): Spaceflight effects on biology
2019 - BioMed Central | BMC Genomics
Joanne Riebschleger, Christine Grové, Daniel L. Cavanaugh, Shane Costello,
Millions of children have a parent with a mental illness (COPMI). These children are at higher risk of acquiring behavioural, developmental and emotional difficulties. Most children, including COPMI, have low levels of mental health literacy (MHL), meaning they do not have accurate, non-stigmatized information. There is limited knowledge about what kind of MHL content should be delivered to children. The aim of this exploratory study is to identify the knowledge content needed for general population ...
Tópico(s): Family Caregiving in Mental Illness
2017 - Multidisciplinary Digital Publishing Institute | Brain Sciences
Christine L. Weber, Terence Cavanaugh,
Tópico(s): Library Collection Development and Digital Resources
2006 - SAGE Publishing | Gifted Child Today
Christine Cannon, John C. Cavanaugh,
Tópico(s): Palliative Care and End-of-Life Issues
1998 - American Psychological Association | Families Systems & Health
Laura K. Hanson, Jacquelyn S. Slater, Victoria J. Cavanaugh, William W. Newcomb, Lisa L. Bolin, Christine Nicole Nelson, Lisa D. Fetters, Qiyi Tang, Jay C. Brown, Gerd G. Maul, Ann E. Campbell,
ABSTRACT Macrophages are an important target cell for infection with cytomegalovirus (CMV). A number of viral genes that either are expressed specifically in this cell type or function to optimize CMV replication in this host cell have now been identified. Among these is the murine CMV (MCMV) US22 gene family member M140, a nonessential early gene whose deletion (RVΔ140) leads to significant impairment in virus replication in differentiated macrophages. We have now determined that the defect in replication ...
Tópico(s): HIV Research and Treatment
2009 - American Society for Microbiology | Journal of Virology
Laura M. Epple, Lynne Bemis, Ryan P. Cavanaugh, Anne Skope, Tehila Mayer-Sonnenfeld, Chad Frank, Christine S. Olver, Alex Lencioni, Nathaniel L. Dusto, Alona Tal, Michael Har-Noy, Kevin O. Lillehei, Emmanuel Katsanis, Michael W. Graner,
Purpose: This paper presents the treatment of a 12-year-old female spayed Great Dane who presented with vestibular signs (ataxia, nystagmus, hind end collapse). Thoracic radiographs revealed a discrete pulmonary nodule in the right cranial lung lobe. Ultrasound-guided fine needle aspirate detected primary bronchoalveolar adenocarcinoma, verified via computed tomography, with a second smaller nodule discovered in the right cranial lung lobe.Materials and methods: A lateral thoracotomy with right cranial ...
Tópico(s): Virus-based gene therapy research
2013 - Taylor & Francis | International Journal of Hyperthermia
R.K. Bhamra, Lois E. Bolcsak, Patricia J. Roberts, Rachel Stevens, Christopher Cavanaugh, Christine E. Swenson,
TLC ELL-12 is a liposomal formulation of the antineoplastic L-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine [L-ET-18-OCH3 (EL)]. The purpose of these studies was to characterize the toxicity and disposition of [N-methyl-14C] L-ET-18-OCH3 administered as TLC ELL-12. Rats received TLC ELL-12 by i.v. infusion into a tail vein as a single 12.5 or 62.5 mg/kg dose or as five daily doses at 12.5 mg/kg (cumulative dose of 62.5 mg/kg). Whole blood and tissue samples were collected over 24 h, and assayed ...
Tópico(s): RNA Interference and Gene Delivery
2003 - Lippincott Williams & Wilkins | Anti-Cancer Drugs
Wenxiu Ma, Ferhat Ay, Choli Lee, Günhan Gülsoy, Xinxian Deng, Savannah Cook, Jennifer Hesson, Christopher Cavanaugh, Carol B. Ware, Anton Krumm, Jay Shendure, C. Anthony Blau, Christine M. Distèche, William Stafford Noble, Zhijun Duan,
The folding and three-dimensional (3D) organization of chromatin in the nucleus critically impacts genome function. The past decade has witnessed rapid advances in genomic tools for delineating 3D genome architecture. Among them, chromosome conformation capture (3C)-based methods such as Hi-C are the most widely used techniques for mapping chromatin interactions. However, traditional Hi-C protocols rely on restriction enzymes (REs) to fragment chromatin and are therefore limited in resolution. We recently ...
Tópico(s): RNA and protein synthesis mechanisms
2018 - Elsevier BV | Methods
Wenxiu Ma, Ferhat Ay, Choli Lee, Günhan Gülsoy, Xinxian Deng, Savannah Cook, Jennifer Hesson, Christopher Cavanaugh, Carol B. Ware, Anton Krumm, Jay Shendure, C. Anthony Blau, Christine M. Distèche, William Stafford Noble, Zhijun Duan,
Targeted DNase Hi-C uses DNase I instead of restriction enzymes for chromatin fragmentation and improves the resolution of chromatin interaction maps. High-throughput methods based on chromosome conformation capture have greatly advanced our understanding of the three-dimensional (3D) organization of genomes but are limited in resolution by their reliance on restriction enzymes. Here we describe a method called DNase Hi-C for comprehensively mapping global chromatin contacts. DNase Hi-C uses DNase ...
Tópico(s): Genomics and Chromatin Dynamics
2014 - Nature Portfolio | Nature Methods
Christine McCauley Ohannessian, Alyson M. Cavanaugh, Kelly Cheeseman,
The purpose of this study was to examine gender and racial/ethnic differences in anxiety during adolescence. Objective: Differences in both symptomatology and clinical levels of anxiety were examined. Method: Surveys were administered in schools to a diverse sample of 1,000 15-17 year-old U.S. adolescents during the Spring of 2007 and the Spring of 2008. Results: When symptomatology scores were assessed, girls had higher levels of generalized anxiety, social anxiety, separation anxiety, panic disorder, ...
Tópico(s): Early Childhood Education and Development
2017 - | Adolescent Psychiatry
Christine Jensen, Michael Ferrari, John C. Cavanaugh,
Tópico(s): Psychological Well-being and Life Satisfaction
2004 - Springer Science+Business Media | Ageing International
Colin M. Tice, Robert E. Hormann, Christine S. Thompson, Jennifer L. Friz, Caitlin K. Cavanaugh, Jessica A. Saggers,
Tópico(s): Insect Pheromone Research and Control
2003 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Colin M. Tice, Robert E. Hormann, Christine S. Thompson, Jennifer L. Friz, Caitlin K. Cavanaugh, Enrique L. Michelotti, Javier Garcia, Ernesto Nicolás, Fernando Alberício,
A lead discovery library and a follow-up focused library of alpha-acylaminoketones were designed based on known dibenzoylhydrazine ecdysone agonists, including GS(TM)-E. The compounds were assayed in mammalian cells expressing the ecdysone receptor from Bombyx mori for their ability to cause expression of a reporter gene downstream of an ecdysone response element. The most potent alpha-acylaminoketones were comparable to GS(TM)-E in this assay.
Tópico(s): Insect Pheromone Research and Control
2003 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Christine Grové, Joanne Riebschleger, Annick Bosch, Daniel L. Cavanaugh, P.C. van der Ende,
Children of parents with a mental illness are at significant risk of developing a mental illness. This risk may be reduced if appropriate interventions are provided that include information and knowledge about mental illness. While there are some interventions for children of parents with a mental illness, research is lacking about the type of mental health information children need and why they need that knowledge. This study presents the perspectives of a purposive sample of international research ...
Tópico(s): Maternal Mental Health During Pregnancy and Postpartum
2017 - Elsevier BV | Children and Youth Services Review
Christine Dubowy, Daniel J. Cavanaugh,
Endogenous circadian rhythms exert strong effects on sleep, but the neuronal mechanisms that produce these effects have remained obscure. New work implicates neuropeptidergic signaling in a subset of circadian clock cells in the regulation of sleep late at night.
Tópico(s): Neurobiology and Insect Physiology Research
2014 - Elsevier BV | Current Biology
Jean Cavanaugh, Shelley D. Miyamoto, Eduardo M. da Cruz, Biagio A. Pietra, David N. Campbell, Max B. Mitchell, Christine Peyton, Jeanine Gruenwald, Jeffrey R. Darst,
A previously healthy, 13-year-old girl presented with new-onset dilated cardiomyopathy, and is placed on a left ventricular assist device (VAD). Herein we describe a unique VAD weaning protocol used to determine the timing and feasibility of a VAD explant.
Tópico(s): Congenital Heart Disease Studies
2009 - Elsevier BV | The Journal of Heart and Lung Transplantation
Élie Haddad, Brent R. Logan, Linda M. Griffith, Rebecca H. Buckley, Roberta Parrott, Susan E. Prockop, Trudy N. Small, Jessica Chaisson, Christopher C. Dvorak, Megan Murnane, Neena Kapoor, Hisham Abdel‐Azim, I. Celine Hanson, Caridad Martinez, Jack Bleesing, Sharat Chandra, Angela R. Smith, Matthew E. Cavanaugh, Soma Jyonouchi, Kathleen E. Sullivan, Lauri M. Burroughs, Suzanne Skoda‐Smith, Ann E. Haight, Audrey G. Tumlin, Troy C. Quigg, Candace Taylor, Blachy J. Dávila Saldaña, Michael D. Keller, Christine M. Seroogy, Kenneth DeSantes, Aleksandra Petrović, Jennifer W. Leiding, David C. Shyr, Hélène Decaluwe, Pierre Teira, Alfred P. Gillio, Alan P. Knutsen, Theodore B. Moore, Morris Kletzel, John Craddock, Victor Aquino, Jeffrey Davis, Lolie C. Yu, Geoff D.E. Cuvelier, Jeffrey J. Bednarski, Frederick D. Goldman, Elizabeth M. Kang, Evan Shereck, Matthew H. Porteus, James A. Connelly, Thomas A. Fleisher, Harry L. Malech, William T. Shearer, Paul Szabolcs, Monica S. Thakar, Mark T. Vander Lugt, Jennifer Heimall, Ziyan Yin, Michael A. Pulsipher, Sung‐Yun Pai, Donald B. Kohn, Jennifer M. Puck, Morton J. Cowan, Richard J. O’Reilly, Luigi D. Notarangelo,
Key Points The genetic cause of SCID impacts on survival and immune reconstitution and should be considered in tailoring HCT for individual patients. Total and naive CD4+ cell counts in SCID patients 6 and 12 months post-HCT predict long-term survival and sustained immune reconstitution.
Tópico(s): Hematopoietic Stem Cell Transplantation
2018 - Elsevier BV | Blood
Christine Fisher, AMY VEHEC, Bashar Kashlan, G. Della Longa, Lowell Houpt, KRISTI HOWE, LISA STARK, Dennis Cavanaugh,
An 81-year-old woman had a history of congestive heart failure with shortness of breath, chest pain, and headaches. A dipyridamole-augmented Tc-99m sestamibi gated SPECT myocardial perfusion scan revealed increased uptake in the axial and appendicular skeleton that increased over time. Subsequent bone marrow biopsy revealed multiple myeloma.
Tópico(s): Peptidase Inhibition and Analysis
2000 - Lippincott Williams & Wilkins | Clinical Nuclear Medicine