Loïc Decrey, Florence Bonvin, Christophe Bonvin, Emmanuel Bonvin, Tamar Kohn,
Powdered activated carbon (PAC) is increasingly used as tertiary treatment for the removal of trace organic contaminants (TrOCs) from wastewater (WW). To enhance the sorption kinetics and capacity, the PAC particles can be milled down to superfine powdered activated carbon (SPAC). However, the small-grained SPAC particles are prone to aggregation, which may impact their treatment performance. In this study we examined the effect of SPAC dispersion and aggregation on TrOC removal kinetics and sorption ...
Tópico(s): Membrane Separation Technologies
2020 - Elsevier BV | Water Research
Martina Goeldlin, Arsany Hakim, Mattia Branca, Stefanie Abend, Markus Kneihsl, Waldo Valenzuela, Sabine Fenzl, Beata Rezny‐Kasprzak, Roman Rohner, Daniel Strbian, Maurizio Paciaroni, Götz Thomalla, Patrik Michel, Krassen Nedeltchev, Thomas Gattringer, Else Charlotte Sandset, Leo H. Bonati, Diana Aguiar de Sousa, PN Sylaja, George Ntaios, Masatoshi Koga, Zuzana Gdovinová, Robin Lemmens, Natan M. Bornstein, Peter J. Kelly, Mira Katan, Thomas Horvath, Jesse Dawson, Urs Fischer, Adedolapo Kamaldee Adeyemi, Vedamurthy Adhiyaman, Adrian Scutelnic, Hisanao Akiyama, A. Wilson, Alexander A. Tarnutzer, Alexander Pichler, Alexander Salerno, Alexander Vanhoorne, Alexandros A. Polymeris, Ami Wilkinson, Ana Paiva Nunes, Anastasia Adamou, André Peeters, Andrea M. Humm, Andrea Zini, Aneesh Dhasan, Angelika Alonso, Anna Fischer, Anna Maija Saukkonen, Anna Maria Müller, Anne Berberich, Anne Falcou, Annemie Devroye, Arne Hostens, Arthur Liesz, Arunkumar Annamalai, Arvind Vijaysharan Sharma, Asterios Paliantonis, Aumugam Nallasivan, Azmil H. Abdul‐Rahim, Ben Grimshaw, Bernd Kallmünzer, Biljana Rodic, Brian Clarke, Brian Menezes, B. Weder, Carla Ciobanu, Carlo W. Cereda, Caroline M.J. Loos, Caterina Kulyk, Catia Gonçalves Martins, Cecilia Ferrari, Christian Fung, Christina M. Caporale, Christine McAlpine, Christoph Globas, Christoph Gumbinger, Christophe Bonvin, Christos Krogias, Clare Whyte, Claudio L. Bassetti, Dan Ryan, Daniel Charissé, Daniel Richter, Daniel Schrammel, Daria Giudici, Darius G. Nabavi, David Bradley, David Orion, David Seiffge, David J. Werring, Davide Strambo, Derek Esson, Dheeraj Khurana, Diana Melância, Dimitre Staykov, Dimitri Hemelsoet, Dominik Michalski, Eckhard Schlemm, Efstathia Karagkiozi, Espen Saxhaug Kristoffersen, Evelyn Marcelis, Fiona Wright, François Delvoye, Friedrich Medlin, Takayuki Fukano, Gaia Sirimarco, Gek Shim, Gemma Smith, Georg Royl, George Pope, Georgia Salanti, Gerli Sibolt, German Guzman-Gutierrez, Gian Marco De Marchis, Giovanni Bianco, Harvey Dymond, Hege Ihle-Hansen, Helen Thomas, Henning Stetefeld, Himanshu Koundal, Honig Asaf, Ijaz Anwar, Ilaria Leone De Magistris, Imelda Noone, Ingrid Olave Bersas, Ioan-Paul Muresan, Isabelle Vanpanteghem, Jan Gralla, Jan Vynckier, Jelle Demeestere, Jens Offermann, Jeyaraj Durai Pandian, João André Sousa, João Pedro Marto, João Sargento‐Freitas, Jochen Vehoff, Johann Pelz, John McCabe, Joseph Harbison, Joshua Mbroh, Judith Wagner, Julien Niederhäuser, Jussi Sipilä, Kanta Tanaka, Karthika Rani, Katarina Klimcikova, Kerry M. Smith, Klaudia Soltesova, Kosmas Macha, Kosuke Matzusono, Kristina Szabo, Laetitia Yperzeele, Lars Alteheld, Lars Kellert, Liam Healy, Liqun Zhang, Loraine Fisch, Luana Gentile, Ludwig Schelosky, Lukas Kellermair, Lukuman Gbadamosh, Lynn Dixon, Makoto Nakajima, Manabu Inoue, Manju Krishnan, Manuel Bolognese, Marcel Arnold, Maria Giulia Mosconi, Marianne Altmann, Marie Lang, Marios Psychogios, Marjaana Tiainen, Mark Barber, Markus Arnold, Marta Magriço, Martin Müller, Mary Joan MacLeod, Matthias Greulich, Matthieu Pierre Rutgers, Maximilian Schell, Melissa Garcia-Pons, Mette Pøhner Skahjem, Michael Haley, Michael Marnane, Milan R. Voško, Mira Katan, Miroslav Mako, Naren Polavarapu, Nicolas Martinez‐Majander, Nicole Del Gaudio, Nicoletta G. Caracciolo, Nils Peters, Niranjan Prakash Mahajan, Norbert Silimon, Oezguer A. Onur, Elisabeth Olbert, Ole Morten Rønning, Peter J. Kelly, Peter A. Ringleb, Peter Slade, Peter Vanacker, Philippe Desfontaines, Priya Nair, Rados Marian, Rajsrinivas Parthasarathy, Rea Hidalgo, Ríona Mulcahy, Risa Kato, Rohit Bhatia, Rónán Collins, Ronen R. Leker, Roni Eichel, Ryota Tanaka, Samer Al Hussayni Husseini, Sandra Clarke, Sapna Erat Sreedharan, Sarah Ostanek, Sellimi Amina, Seraina Beyeler, Sharon Storton, Shigeru Fujimoto, Silja Räty, Simon Fandler‐Höfler, Sofia Galego, Sohei Yoshimura, Soichiro Matsubara, Stefan Greisenegger, Stefan Oberndorfer, Sucharita Ray, Susanne Renaud, Susanne Riebau, Sven Poli, Svetlana Politz, Sylvan J. Albert, Takenobu Kunieda, Takeo Sato, Takeshi Yoshimoto, Tal Anjum, Tatjana Pap, Telma Costa, Teresa M. V. D. Pinho e Melo, Thomas Iype, Tim Cassidy, Tim J. von Oertzen, Timo Kahles, Toni Danilo, Torstein Spetalen, Turgut Tatlisumak, Veerle De Herdt, Victoria Borisova, Vijaya Pamidimukkala, Vikram Huded, Vipul Gupta, V.V. Krishna Kumar, Vivek Nambiar, Waltraud Pfeilschifter, Wendy Stoop, Yasuyuki Iguchi, Yngve Müller Seljeseth, Youssif Abousleiman, Yusuke Yakushiji, Zoltan Pencz,
Whether infarct size modifies the treatment effect of early vs late direct oral anticoagulant (DOAC) initiation in people with ischemic stroke and atrial fibrillation is unknown.
Tópico(s): Venous Thromboembolism Diagnosis and Management
2024 - American Medical Association | JAMA Neurology
Martina Goeldlin, Achim Mueller, Bernhard Siepen, Madlaine Mueller, Davide Strambo, Patrik Michel, Michael Schaerer, Carlo W. Cereda, Giovanni Bianco, Florian Lindheimer, Christian Berger, Friedrich Medlin, Roland Backhaus, Nils Peters, Susanne Renaud, Loraine Fisch, Julien Niederhaeuser, Emmanuel Carrera, Elisabeth Dirren, Christophe Bonvin, Rolf Sturzenegger, Timo Kahles, Krassen Nedeltchev, Georg Kaegi, Jochen Vehoff, Biljana Rodic, Manuel Bolognese, Ludwig Schelosky, Stephan Salmen, Marie‐Luise Mono, Alexandros A. Polymeris, Stefan T. Engelter, Philippe Lyrer, Susanne Wegener, Andreas R. Luft, Werner J. Z’Graggen, David Bervini, Bastian Volbers, Tomas Dobrocky, Johannes Kaesmacher, Pasquale Mordasini, Thomas R. Meinel, Marcel Arnold, Javier Fandino, Leo H. Bonati, Urs Fischer, David Seiffge,
Knowledge about different etiologies of non-traumatic intracerebral hemorrhage (ICH) and their outcomes is scarce.We assessed prevalence of pre-specified ICH etiologies and their association with outcomes in consecutive ICH patients enrolled in the prospective Swiss Stroke Registry (2014 to 2019).We included 2,650 patients (mean±standard deviation age 72±14 years, 46.5% female, median National Institutes of Health Stroke Scale 8 [interquartile range, 3 to 15]). Etiology was as follows: hypertension, ...
Tópico(s): Neurosurgical Procedures and Complications
2022 - | Journal of Stroke
Elena Ardila Jurado, Veit Sturm, Florian Brugger, Krassen Nedeltchev, Marcel Arnold, Leo H. Bonati, Emmanuel Carrera, Patrik Michel, Carlo W. Cereda, Manuel Bolognese, Sylvan Albert, Friedrich Medlin, Christian Berger, Ludwig Schelosky, Susanne Renaud, Julien Niederhäuser, Christophe Bonvin, Marie‐Luise Mono, Biljana Rodic, Alexander A. Tarnutzer, Guido Schwegler, Stephan Salmen, Andreas R. Luft, Nils Peters, Jochen Vehoff, Georg Kägi,
Central retinal artery occlusion (CRAO) often leads to permanent monocular blindness. Hence, early recognition and rapid re-perfusion is of paramount importance. This study aims to describe prehospital pathways in CRAO compared to stroke and study the knowledge about CRAO.(1) Description of baseline characteristics, prehospital pathways/delays, and acute treatment (thrombolysis/thrombectomy vs. standard of care) of patients with CRAO and ischemic stroke registered in the Swiss Stroke Registry. (2) ...
Tópico(s): Intraoperative Neuromonitoring and Anesthetic Effects
2022 - Frontiers Media | Frontiers in Neurology
Steven Hajdu, Johannes Kaesmacher, Patrik Michel, Gaia Sirimarco, Jean‐François Knebel, Bruno Bartolini, Christoph C. Kurmann, Francesco Puccinelli, Pascal J. Mosimann, Christophe Bonvin, Marcel Arnold, Julien Niederhäuser, Ashraf Eskandari, Pasquale Mordasini, Jan Gralla, Urs Fischer, Guillaume Saliou,
To investigate the association between endovascular therapy (EVT) start time in acute ischemic stroke (AIS) and midterm functional outcome.This retrospective cohort study included all patients with AIS treated with EVT from 2 stroke center registries from January 2012 to December 2018. The primary outcome was the score on the modified Rankin Scale (mRS) and the utility-weighted mRS (uw-mRS) at 90 days. A proportional odds model was used to calculate the common odds ratio (OR) as a measure of the likelihood ...
Tópico(s): Healthcare Operations and Scheduling Optimization
2021 - Lippincott Williams & Wilkins | Neurology
Davide Strambo, Gian Marco De Marchis, Leo H. Bonati, Marcel Arnold, Emmanuel Carrera, Santi Galletta, Krassen Nedeltchev, Timo Kahles, Carlo W. Cereda, Giovanni Bianco, Georg Kägi, Andreas R. Luft, Manuel Bolognese, Lehel‐Barna Lakatos, Stephan Salmen, Pamela Correia, Rolf Sturzenegger, Sylvan Albert, Friedrich Medlin, Christian Berger, Florian Lindheimer, Markus R. Baumgartner, Ludwig Schelosky, Christophe Bonvin, Marie‐Luise Mono, Biljana Rodic, Andrea von Reding, Guido Schwegler, Federico Massini, Alexander A. Tarnutzer, Shadi Taheri, Nils Peters, Morin Beyeler, Valerian Altersberger, Stefan T. Engelter, Urs Fischer, Patrik Michel,
Abstract Background Most case series of patients with ischemic stroke (IS) and COVID‐19 are limited to selected centers or lack 3‐month outcomes. The aim of this study was to describe the frequency, clinical and radiological features, and 3‐month outcomes of patients with IS and COVID‐19 in a nationwide stroke registry. Methods From the Swiss Stroke Registry (SSR), we included all consecutive IS patients ≥18 years admitted to Swiss Stroke Centers or Stroke Units during the first wave of COVID‐19 (25 ...
Tópico(s): Retinal and Optic Conditions
2021 - Wiley | European Journal of Neurology
Thomas R. Meinel, Mattia Branca, Gian Marco De Marchis, Krassen Nedeltchev, Timo Kahles, Leo H. Bonati, Marcel Arnold, Mirjam R. Heldner, Simon Jung, Emmanuel Carrera, Elisabeth Dirren, Patrik Michel, Davide Strambo, Carlo W. Cereda, Giovanni Bianco, Georg Kägi, Jochen Vehoff, Mira Katan, Manuel Bolognese, Roland Backhaus, Stephan Salmen, Sylvan Albert, Friedrich Medlin, Christian Berger, Ludwig Schelosky, Susanne Renaud, Julien Niederhäuser, Christophe Bonvin, Michael Schaerer, Marie‐Luise Mono, Biljana Rodic, Alexander A. Tarnutzer, Pasquale Mordasini, Jan Gralla, Johannes Kaesmacher, Stefan T. Engelter, Urs Fischer, David Seiffge,
The aim was to evaluate, in patients with atrial fibrillation (AF) and acute ischemic stroke, the association of prior anticoagulation with vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) with stroke severity, utilization of intravenous thrombolysis (IVT), safety of IVT, and 3-month outcomes.This was a cohort study of consecutive patients (2014-2019) on anticoagulation versus those without (controls) with regard to stroke severity, rates of IVT/mechanical thrombectomy, symptomatic intracranial ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2020 - Wiley | Annals of Neurology
Jeremy Jankovic, Vincianne Rey Bataillard, Noëlle Mercier, Christophe Bonvin, Patrik Michel,
Background Intravenous thrombolysis is a well-established treatment of ischemic stroke within 4.5 h. However, its effectiveness in acute ischemic myelopathy is unknown. Purpose We describe a series of four acute ischemic myelopathy patients treated with intravenous thrombolysis within 4.5 h and review the current literature to explore this treatment feasibility, potential safety, and efficacy. Methods We reviewed all routinely collected clinical, radiological, and follow-up data of patients with ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2019 - SAGE Publishing | International Journal of Stroke
Robert Tarr, Dan Hsu, Zsolt Kulcsàr, Christophe Bonvin, Daniel A. Rüfenacht, Karsten Alfke, Robert Stingele, Olav Jansen, Donald Frei, Richard Bellon, Michael T. Madison, Tobias Struffert, Arnd Dörfler, Iris Q. Grunwald, Wolfgang Reith, A. Haaß,
Background and purpose The purpose of this study was to assess the initial post-market experience of the device and how it is compared with the Penumbra Pivotal trial used to support the 510k application. Methods A retrospective case review of 157 consecutive patients treated with the Penumbra system at seven international centers was performed. Primary endpoints were revascularization of the target vessel (TIMI score of 2 or 3), good functional outcome as defined by a modified Rankin scale (mRS) ...
Tópico(s): Peripheral Artery Disease Management
2018 - BMJ | Journal of NeuroInterventional Surgery
Christophe Bonvin, Bastian Etter, Kai M. Udert, Emmanuel Frossard, Simone Nanzer, Federica Tamburini, Astrid Oberson,
Urine contains about 50 % of the phosphorus (P) and about 90 % of the nitrogen (N) excreted by humans and is therefore an interesting substrate for nutrient recovery. Source-separated urine can be used to precipitate struvite or, through a newly developed technology, nitrified urine fertilizer (NUF). In this study, we prepared 33P radioisotope- and stable 15N isotope-labeled synthetic NUF (SNUF) and struvite using synthetic urine and determined P and N uptake by greenhouse-grown ryegrass (Lolium multiflorum ...
Tópico(s): Constructed Wetlands for Wastewater Treatment
2015 - Springer Science+Business Media | AMBIO
Hubertus Fritz Georg Müller, Aurélien Viaccoz, Loraine Fisch, Christophe Bonvin, Karl‐Olof Lövblad, Osman Ratib, Patrice H. Lalive, Sabrina Pagano, Nicolas Vuilleumier, Jean‐Pierre Willi, Roman Sztajzel,
We investigated whether uptake of (18)fluoro-2-deoxy-d-glucose (18FDG) positron emission tomography-computed tomography (PET-CT) correlated to clinical symptoms and presence of microembolic signals (MES) detected by transcranial Doppler in patients with carotid stenosis.18FDG-PET-CT and MES detection was performed in consecutive patients with 50% to 99% symptomatic or asymptomatic carotid stenoses. Uptake index was defined by a target to background ratio (TBR) between maximum standardized uptake value ...
Tópico(s): Cardiac Imaging and Diagnostics
2014 - Lippincott Williams & Wilkins | Stroke
Hubertus Fritz Georg Müller, Aurélien Viaccoz, Igor Kuzmanović, Christophe Bonvin, Karim Burkhardt, Marie‐Luce Bochaton‐Piallat, Roman Sztajzel,
The aim of our study was to evaluate whether neo-vascularization of the carotid plaque can be accurately assessed by visual analysis of contrast-enhanced ultrasound images and whether these findings correlate with intensity-over-time curve analysis (ITC) and histopathology. Patients with ≥50% symptomatic or ≥60% asymptomatic stenosis according to European Carotid Surgery Trial criteria were included. Four investigators evaluated contrast enhancement visually (three grades), with positive agreement when ...
Tópico(s): Acute Ischemic Stroke Management
2013 - Elsevier BV | Ultrasound in Medicine & Biology
Isabelle Momjian‐Mayor, Igor Kuzmanović, Shahan Momjian, Christophe Bonvin, Stefane Albanese, Denis Bichsel, Mario Comelli, Vitor Augusto da Rosa Pereira, Karl‐Olof Lövblad, Roman Sztajzel,
The purpose of this study was to determine the accuracy of a risk index in symptomatic or asymptomatic carotid stenoses.Consecutive patients presenting 50% to 99% carotid stenoses were included. A semiautomated gray scale-based color mapping (red, yellow, and green) of the whole plaque and of its surface was achieved. Surface was defined as the region located between the lumen (Level 0) and, respectively, 0.5, 1, 1.5, and 2 mm. Risk index was based on a combination of degree of stenosis and the proportion ...
Tópico(s): Intracranial Aneurysms: Treatment and Complications
2012 - Lippincott Williams & Wilkins | Stroke
Robert F. Bonvini, Roman Sztajzel, P.‐A. Dorsaz, Marc Righini, Christophe Bonvin, Jasmina Alibegovic, Ulrich Sigwart, Edoardo Camenzind, Vitali Verin, Juan Sztajzel,
The occurrence of atrial fibrillation after percutaneous closure of a patent foramen ovale for cryptogenic stroke has been reported in a variable percentage of patients. However, its precise incidence and mechanism are presently unclear and remain to be elucidated.Prospective follow-up study.Ninety-two patients undergoing a percutaneous patent foramen ovale closure procedure (closure group) for cryptogenic stroke were compared with a similar group of 51 patients, who were medically treated.A systematic ...
Tópico(s): Aortic Disease and Treatment Approaches
2010 - SAGE Publishing | International Journal of Stroke
Magalie Viallon, S. Altrichter, Vítor Mendes Pereira, Duy Nguyen, Lučka Šekoranja, Andrea Federspiel, Zsolt Kulcsàr, Roman Sztajzel, Rafik Ouared, Christophe Bonvin, Josef Pfeuffer, Karl‐Olof Lövblad,
In acute stroke it is no longer sufficient to detect simply ischemia, but also to try to evaluate reperfusion/recanalization status and predict eventual hemorrhagic transformation. Arterial spin labeling (ASL) perfusion may have advantages over contrast-enhanced perfusion-weighted imaging (cePWI), and susceptibility weighted imaging (SWI) has an intrinsic sensitivity to paramagnetic effects in addition to its ability to detect small areas of bleeding and hemorrhage. We want to determine here if their ...
Tópico(s): MRI in cancer diagnosis
2010 - Karger Publishers | European Neurology
Robert Tarr, Dan Hsu, Zsolt Kulcsàr, Christophe Bonvin, Daniel A. Rüfenacht, Karsten Alfke, Robert Stingele, Olav Jansen, Donald Frei, Richard Bellon, Michael T. Madison, Tobias Struffert, Arnd Dörfler, Iris Q. Grunwald, Wolfgang Reith, A. Haaß,
Background and purpose The purpose of this study was to assess the initial post-market experience of the device and how it is compared with the Penumbra Pivotal trial used to support the 510k application. Methods A retrospective case review of 157 consecutive patients treated with the Penumbra system at seven international centers was performed. Primary endpoints were revascularization of the target vessel (TIMI score of 2 or 3), good functional outcome as defined by a modified Rankin scale (mRS) ...
Tópico(s): Stroke Rehabilitation and Recovery
2010 - BMJ | Journal of NeuroInterventional Surgery
Zsolt Kulcsàr, Christophe Bonvin, Karl‐Olof Lövblad, Benjamin Gory, Hasan Yilmaz, Roman Sztajzel, Daniel A. Rüfenacht,
Major cerebral thromboembolism often resists recanalization with currently available techniques. The authors present their initial experience with a self-expanding stent for use in intracranial vascular reconstruction, permitting immediate recanalization of acute thromboembolic occlusions of the anterior circulation. Patients treated with the Cordis Enterprise™ self-expanding intracranial stent system for acute thromboembolic occlusion of the major anterior cerebral arteries were included. Treatment ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2010 - Springer Science+Business Media | Clinical Neuroradiology
Michael Payer, C. Sottas, Christophe Bonvin,
Superficial siderosis of the central nervous system is a rare disorder with hemosiderin deposition in the spinal and cranial leptomeninges and subpial layer, mostly from repetitive subarachnoid hemorrhage. Progressive sensorineural deafness, cerebellar ataxia, and pyramidal signs comprise the typical clinical presentation. We describe a 47-year-old patient, who showed initial 2-year improvement after successful occlusion of an intradural bleeding source at T4. Secondary progression of symptoms without ...
Tópico(s): Amyotrophic Lateral Sclerosis Research
2010 - Springer Science+Business Media | Acta Neurochirurgica
Zsolt Kulcsár, Christophe Bonvin, Vítor Mendes Pereira, S. Altrichter, Hasan Yilmaz, Karl‐Olof Lövblad, Roman Sztajzel, Daniel A. Rüfenacht,
Large IC artery occlusion is often resistant to recanalization. We present our initial experience with the PS.Presenting with a severe acute ischemic stroke, the first 27 consecutive patients were considered for thromboaspiration therapy and retrospective data base analysis. All patients received standard thrombectomy treatment as monotherapy or in combination with thrombolysis or IC stent placement. The primary end point was revascularization of the target vessel to grade 2 or 3 on the TICI scale. ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2009 - American Society of Neuroradiology | American Journal of Neuroradiology
A. -S. Knoepfli, Lučka Šekoranja, Christophe Bonvin, J. Delavelle, Zsolt Kulcsàr, Daniel A. Rüfenacht, Hasan Yilmaz, Roman Sztajzel, S. Altrichter, Karl‐Olof Lövblad,
To evaluate the prognostic accuracy of combining perfusion CT (PCT) and thrombolysis in brain ischemia (TIBI) ultrasonographic grade in the triage of stroke patients who will benefit from thrombolysis and in predicting the clinical outcome.We conducted a prospective study of all consecutive stroke patients admitted to our hospital from March 2003 to July 2007, presenting with signs of acute stroke within the therapeutic window, who had undergone either intravenous or combined intravenous and intra- ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2008 - Elsevier BV | Journal of Neuroradiology
Christophe Bonvin, Judit Horváth, Blaise Christe, Théodor Landis, Pierre R. Burkhard,
Abstract We report on two patients with advanced Parkinson's disease who were exhibiting a peculiar and stereotyped behavior characterized by an irrepressible need to sing compulsively when under high‐dose dopamine replacement therapy. Sharing many features with punding, this singing behavior is proposed as a distinct manifestation of the dopamine dysregulation syndrome in Parkinson's disease. Ann Neurol 2007
Tópico(s): Neurological disorders and treatments
2007 - Wiley | Annals of Neurology
Zsolt Kulcsàr, Hasan Yilmaz, Christophe Bonvin, Karl‐Olof Lövblad, Daniel A. Rüfenacht,
In some patients with acute cerebral vessel occlusion, navigating mechanical thrombectomy systems is difficult due to tortuous anatomy of the aortic arch, carotid arteries, or vertebral arteries. Our purpose was to describe a multiple coaxial catheter system used for mechanical revascularization that helps navigation and manipulations in tortuous vessels. A triple or quadruple coaxial catheter system was built in 28 consecutive cases presenting with acute ischemic stroke. All cases were treated ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2010 - Springer Science+Business Media | CardioVascular and Interventional Radiology
Urs Fischer, Mattia Branca, Leo H. Bonati, Emmanuel Carrera, María Isabel Vargas, Alexandra Platon, Zsolt Kulcsàr, Susanne Wegener, Andreas R. Luft, David Seiffge, Marcel Arnold, Patrik Michel, Davide Strambo, Vincent Dunet, Gian Marco De Marchis, Ludwig Schelosky, Gustav Andreisek, Filip Barinka, Nils Peters, Loraine Fisch, Krassen Nedeltchev, Carlo W. Cereda, Georg Kägi, Manuel Bolognese, Stephan Salmen, Rolf Sturzenegger, Friedrich Medlin, Christian Berger, Susanne Renaud, Christophe Bonvin, Michael Schaerer, Marie‐Luise Mono, Biljana Rodic, Marios Psychogios, Pasquale Mordasini, Jan Gralla, Johannes Kaesmacher, Thomas R. Meinel,
To examine rates of intravenous thrombolysis (IVT), mechanical thrombectomy (MT), door-to-needle (DTN) time, door-to-puncture (DTP) time, and functional outcome between patients with admission magnetic resonance imaging (MRI) versus computed tomography (CT).An observational cohort study of consecutive patients using a target trial design within the nationwide Swiss-Stroke-Registry from January 2014 to August 2020 was carried out. Exclusion criteria included MRI contraindications, transferred patients, ...
Tópico(s): Stroke Rehabilitation and Recovery
2022 - Wiley | Annals of Neurology
Gian Marco De Marchis, Patrick R. Wright, Patrik Michel, Davide Strambo, Emmanuel Carrera, Elisabeth Dirren, Andreas R. Luft, Susanne Wegener, Carlo W. Cereda, Georg Kägi, Jochen Vehoff, Henrik Gensicke, Philippe Lyrer, Krassen Nedeltchev, Timo Khales, Manuel Bolognese, Stephan Salmen, Rolf Sturzenegger, Christophe Bonvin, Christian Berger, Ludwig Schelosky, Marie‐Luise Mono, Biljana Rodic, Andrea von Reding, Guido Schwegler, Alexander A. Tarnutzer, Friedrich Medlin, Andrea M. Humm, Nils Peters, Morin Beyeler, Lilian Kriemler, David Bervini, Javier Fandino, Lars G. Hemkens, Pasquale Mordasini, Marcel Arnold, Urs Fischer, Leo H. Bonati,
In Switzerland, the COVID-19 incidence during the first pandemic wave was high. Our aim was to assess the association of the outbreak with acute stroke care in Switzerland in spring 2020.This was a retrospective analysis based on the Swiss Stroke Registry, which includes consecutive patients with acute cerebrovascular events admitted to Swiss Stroke Units and Stroke Centers. A linear model was fitted to the weekly admission from 2018 and 2019 and was used to quantify deviations from the expected ...
Tópico(s): Climate Change and Health Impacts
2021 - Wiley | European Journal of Neurology
Claudia Bigoni, Sarah B. Zandvliet, Elena Beanato, Andrea Crema, Martina Coscia, Arnau Espinosa, Tina Henneken, Julie Hervé, Meltem Oflar, Giorgia G. Evangelista, Takuya Morishita, Maximilian J. Wessel, Christophe Bonvin, Jean-Luc Turlan, Niels Birbaumer, Friedhelm C. Hummel,
Effective, patient-tailored rehabilitation to restore upper-limb motor function in severely impaired stroke patients is still missing. If suitably combined and administered in a personalized fashion, neurotechnologies offer a large potential to assist rehabilitative therapies to enhance individual treatment effects. AVANCER (clinicaltrials.gov NCT04448483) is a two-center proof-of-concept trial with an individual based cumulative longitudinal intervention design aiming at reducing upper-limb motor ...
Tópico(s): EEG and Brain-Computer Interfaces
2022 - Frontiers Media | Frontiers in Neurology
Lisa Fleury, Philipp Koch, Maximilian J. Wessel, Christophe Bonvin, Diego San Millán, Christophe Constantin, Philippe Vuadens, Jan Adolphsen, Andéol Cadic Melchior, Julia Brügger, Elena Beanato, Martino Ceroni, Pauline Menoud, Diego de León Rodríguez, Valérie Zufferey, Nathalie H. Meyer, Philip Egger, Sylvain Harquel, Traian Popa, Estelle Raffin, Gabriel Girard, Jean‐Philippe Thiran, Claude Vaney, Vincent Alvarez, Jean-Luc Turlan, Andreas Mühl, Bertrand Léger, Takuya Morishita, Silvestro Micera, Olaf Blanke, Dimitri Van De Ville, Friedhelm C. Hummel,
Despite recent improvements, complete motor recovery occurs in <15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments to each individual patient. However, there is a lack of knowledge concerning the precise neuronal mechanisms underlying the degree and course of motor recovery and its individual differences, especially in the view of brain network properties despite the fact that it became more and more clear that stroke is a network disorder. The ...
Tópico(s): Stroke Rehabilitation and Recovery
2022 - Frontiers Media | Frontiers in Neurology
Patrik Michel, Michael Diepers, Pasquale Mordasini, Tilman Schubert, David Bervini, Jean-Daniel Rouvé, Yvan Gasche, Guido Schwegler, Christophe Bonvin, Krassen Nedeltchev, Emmanuel Carrera, Georg Kägi, Carlo W. Cereda, Thomas Nyffeler, Stephan G. Wetzel, Susanne Wegener, Henrik Gensicke, Stefan T. Engelter, Marcel Arnold,
In acute ischemic stroke, intravenous thrombolysis (IVT) and acute endovascular therapy (EVT) have been shown to reduce long-term disability in randomized trials. International guidelines are partially not up to date and may not address situations for which there is limited scientific evidence. The goals of the present guidelines are to summarize the current scientific data for acute revascularization treatments to make sure that all Swiss Centers apply a similar, evidence, or consensus-based treatment ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2021 - SAGE Publishing | Clinical and Translational Neuroscience
Sylvain Harquel, Andéol Cadic‐Melchior, Takuya Morishita, Lisa Fleury, Adrien Witon, Martino Ceroni, Julia Brügger, Nathalie H. Meyer, Giorgia G. Evangelista, Philip Egger, Elena Beanato, Pauline Menoud, Dimitri Van De Ville, Silvestro Micera, Olaf Blanke, Bertrand Léger, Jan Adolphsen, Caroline Jagella, Christophe Constantin, Vincent Alvarez, Philippes Vuadens, Jean-Luc Turlan, Andreas Mühl, Christophe Bonvin, Philipp Koch, Maximilian J. Wessel, Friedhelm C. Hummel,
Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used transcranial magnetic stimulation (TMS)-electroencephalography coupling to study cortical reactivity and intracortical GABAergic inhibition, as well as their relationship to residual motor function and recovery longitudinally in patients with stroke.
Tópico(s): Functional Brain Connectivity Studies
2024 - Lippincott Williams & Wilkins | Stroke
Isis Atallah, Mathieu Quinodoz, Belinda Campos‐Xavier, Virginie G. Peter, Athina Fouriki, Christophe Bonvin, Armand Bottani, Camille Kumps, Federica Angelini, Felicitas Bellutti Enders, Stéphanie Christen‐Zaech, Mattia Rizzi, Raffaele Renella, Maja Beck‐Popovic, Claudia Poloni, Valérie Frossard, Jean‐Louis Blouin, Carlo Rivolta, Orbicia Riccio, Fabio Candotti, Michaël Hofer, Sheila Unger, Andrea Superti‐Furga,
Abstract Four individuals from two families presented with a multisystemic condition of suspected genetic origin that was diagnosed only after genome analysis. The main phenotypic features were immune system dysregulation (severe immunodeficiency with autoimmunity) and intellectual disability. The four individuals were found to be homozygous for a 4.4 Kb deletion removing exons 20–23 (NM_003291.4) of the TPP2 gene, predicting a frameshift with premature termination of the protein. The deletion was ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2021 - Wiley | Clinical Genetics
Christophe Bonvin, Isabelle Momjian‐Mayor, Lučka Šekoranja, Karl‐Olof Lövblad, S. Altrichter, H. Levent Yılmaz, Vítor Mendes Pereira, Jaouad Loulidi, Mario Comelli, Pierre R. Burkhard, Roman Sztajzel,
Objective To determine clinical, neuroradiological or ultrasonographic parameters associated with early recanalization and clinical outcome in patients treated with intravenous (IVT) or combined intravenous–intra-arterial (IVT–IAT) thrombolysis. Methods From 2004 to 2007, all consecutive ischemic stroke patients admitted within a 3-hour window and who underwent thrombolytic therapy were reviewed. Degree of occlusion and recanalization during IVT was assessed by transcranial color-coded ultrasound ( ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2010 - Elsevier BV | Journal of the Neurological Sciences