Clive Coleman, Gesche Ipsen, Andrew Robson, Janice Turner, Amanda Andrews, Simon Barnes Chief Sports Writer, Peter Brookes, Christina Hardyment, Sacha Baron Cohen, Cath Urquhart, Charles Saumarez Smith Director, Edward Owen, Robert Cole, With Mark and Magnus, Rupert Mellor, George Bathurst, Martin Geake, Neelam Verjee, Alexandra Frean, Erica Wanger, Zachary Leader, Simon Hill, Amanda Ursell, Simon Barnes, Tim Carbury, Alexandra Blair, Stan Smith, Jane MacQuitty, Paul Bompard, David Wilson, Hannah Devlin, Michael Owen, Mark Frary, John Mulvey, Clare Lazaro, Silke Wichert, Philip Howard, Hannah Betts, Paul Dunn, Carol Midgley, Michael Houlihan Director, John Freeman, David Lister Scotland Correspondent, Christine Seib, David Chater, Ben Hoyle Arts Reporter, Joanna Bale, Suna Erdem, James Bone, James Ducker, Rachel Campbell-Johnston, Clive Davis, John F. Colin, Gabrielle Starkey, Robert Louis Stevenson, Joy Plowman, Carl Mortished, Joseph Conrad, Will Pavia, Ros Savill Director, James Hider, Giles Coren, Robin Pagnamenta, John Leighton Director, David Sharrock, Vivienne Parry, Sir Nicholas Serota Director, Dr Copperfield, Ben Webster Transport Correspondent, Pat Gibson, Nancy Durrant, Patrica Parker, Stewart Tendler Crime Correspondent, Jack Malvern, Dominic Walsh, Ruth Gledhill, Rachel Holmes, Debra Craine, Gary Jacob, Mike Pattenden, Allan Simmons, Dr Jane Collins, Tim Reid, Daniel Finkelstein, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Dan Sabbagh, Tom Gatti, Candida Crewe, Jo Morris, Nicholas Blanford, Robin Young, Robert Crawford Director, Francesca Price, Rhys Blakely, Ann Aranha, Tina Gaudoin, Jack Lohman Director, David Hands, Graham Keeley, Matt Dickinson Chief Football Correspondent, Maurice Alexander, Lucy Sweeney, Frank Saddington, Tim Teeman, Edward Gorman, Derwent May, Louise Welsh, Sandy Nairne Director, Russell Kempson, Paula Hawkins, Frank Wiechula, Daniel McGrory, R. Lew, Klamath Falls, Richard Beeston Ned Parker, Gary Duncan Economics Editor, Oliver Kay, Ed Potton, Sarah Vine, Mark Atherton, Jane Wheatley, Pete Paphides, Stephen Burgen, Antonia Senior Personal Finance Editor, Louisa Barnett, Sally Baker, Christopher Martin-Jenkins, Geza Vermes, David Baddiel, Paul Skinner, Tom Perrotta, Simon de Bruxelles, Tom's Kitchen, Richard Beeston, Daniel McGrory, Tony Halpin, Rob Wright, Christina Koning, Magnus Grimond, David Watts, Michael Palin, Timothy Knox Director, R. Fenwick, Mary Donald, Raymond Keene, Adam Sage, Suzi Godson, Matthew Pryor, Rebecca O'Connor, Bruce Dessau, Gordon Ramsay, Eve Hesov, Mark Jones Director, Jane MaCartney, Chris Newbery Director, Jeannette Hyde, Nigel Hawkes, Niki Austin, Fran Yeoman, Helen Nugent, Richard Owen, Christopher Martin-Jenkins Chief Cricket Correspondent, Marcus Leroux, Ross Leckie, John Ollis, Roger Boyes, Richard Siddle, Susan Cameron, James Charles, Peter Dixon, Nick Hasell, Thomasina Miers, Alison Balsom, James Naughtie, David Hands Rugby Correspondent, Rosemary Bennett Social Affairs Correspondent, Julian Muscat, Paul Simons, Mike Mulvihill, Ann Brady, Wayne Coyne, Steve Jelbert, Michael Fopp Director, Joanna Pitman, Amrit Dhillon, Joan Hobbs, James Doran, Neil MacGregor Director, Philip Webster Political Editor, Tosin Sulaiman, Robert Crampton, Ian Johns, Dominic Maxwell, Anthony Browne Chief Political Correspondent, Sophie Heawood, Matthew Parris, (Christine Buckley), Mark Bridge, Virginia Blackburn, Thomas Catan, Martin McPhillips, Amanda Craig, Michael J. Gray, Christmas Shopping, Sheila Keating, Alan Lee, Caitlin Moran, Iain Finlayson, Neil Fisher, Stephen Andertion, Sharon Osbourne, Richard Beeston, Jeff Tall Director, Ben Webster, Derek Davies, Philip Webster, Graham Searjeant, John Naish, John Lewis, Catherine Philp, Martin Waller, Michael Horsnell, Mark Henderson, Anne-Maire Duff, James Jackson, Carl Mortished International Business Editor, David Cameron, Nigel Hawkes Health Editor, Sarah Butler, Ashling O'Connor, Anna Shepard, Benedict Nightingale, Louise Cohen, Angus Batey, Sam Coates Political Correspondent, (Tom Bawden), Dr Thomas Stuttaford, Stephen Dalton, Richard Morrison, Bill Edgar, Tom Chesshyre, Tony Halpin, Alyson Rudd, James Christopher, Valerie Grove, Ed Hawkins, Merry Clinique, Rob Lewis, Dr David Binnie, Philip Oltermann, Benedict Birnberg, Alan Lee Racing Correspondent, Mystery Guest, Andy McNab, Alan Jackson, Garry Jenkins, Peter Townley, Douglas Kennedy, Jane Glbbin, Bryce Elder, Jane Macartney, Chris Thomas, Mark Bristow, Tom Bower, Stephen Pollard,
... of wine? The prince of fantasy rides out Christopher Paolini's secluded childhood led him into a world ...
2006 - Gale Group | TDA
Jonathan L. Halperin, Daniel Wojdyla, Jonathan P. Piccini, Yuliya Lokhnygina, Manesh R. Patel, Günter Breithardt, Daniel E. Singer, Richard C. Becker, Werner Hacke, John F. Paolini, Christopher C. Nessel, Kenneth W. Mahaffey, Robert M. Califf, Keith A.A. Fox,
Background: Nonvalvular atrial fibrillation (AF) affects 5-10% of people over 75 years of age, in whom the risk of thromboembolism is higher than in younger individuals. Although warfarin protects against ischemic stroke, many patients cannot sustain treatment because of bleeding, drug interactions and coagulation monitoring. The oral Factor Xa inhibitor, rivaroxaban, displayed noninferior efficacy and safety as an alternative anticoagulant in the ROCKET-AF trial (median age 73 years). This analysis ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2012 - Lippincott Williams & Wilkins | Stroke
Steven Shukor, Jonathan Northcroft, Waldemar Januszczak, John Dugdale, Clare Chapman, Simon Archer, Matthew Wall, Barbara Hall, Steve Jones, David Mills, Jim Munro, Jon Swain, Helen Davies, Michele Couston, Peter Whittle, Sally Brock, Rob Hughes, John Peter, Professor Gideon Garter, Jonathan Miller, Jason Page, Lesley White, Christopher Somerville, Oliver Hutcheon, Susan d'Arcy, R A Duvant, Patricia Hewitt Trade & Industry Secretary, Frank Whitford, Nicolette Jones, Jonathan Barford, Terence Blacker, Ferdinand Mount, David Gower, Sam Gilpin, Christopher Chetwode, Peter Done Managing director, Melanie Rickey, David Smith, Mitchell Prothero, Tim Richards, Alastair McCall, Steven Poole, Nick Pitt, David Cohen, Neil Wormald, Richard Green, E P, Andrew Sullivan, Clive Davis, Nicholas Alexander, Andrew Porter, Anne Robinson, Vincenzo Recchia, Tony Allen-Mills, Simon Wilde, Karen Pickering, Martin James, Tom Walker, Robert Winnett, Irwin Stelzer, Keri Allan, Tom English, Robert Hewison, Peter Wilson, Viv Richards, Sumit Ghosh, Rosie Millard, Lawrence Dallaglio, David Dougill, Malavika Sangghvi, Louise Armitstead Editor, Victor Biraben, George Piper, Frank Graham, Chris Burkham, P Quinton, John Adamson, Jeremy Atiyah, Nick Speed, Anne-Marie Conway, David Bond, Jonathon Carr-Brown, Alasdair Reid, Margarette Driscoll, Geraldine Hackett Education Correspondent, Hugh Canning, Jeremy Clarkson, David Cairns, Edward Porter, Peter Conradi, Philip Smith, Stewart Lee, Victoria Segal, Alan Brownjohn, Anthony Peregrine, Sarah Dempster, Dave Pollard, David Eimer, James Lasdun, Fikret Mujicic, Adam Nathan, Corey Boles, Tiff Needell, Shelley von Strunckel, Benoit Philippe, Jeremy Guscott, Paula Robinson, Mary Brittain, Richard Johnson, Mike Laws, Roger Eglin, Stefan Stern, Paul Donovan, Simon O'Connell, Francis Phillips, Dr Stephen Lockwood, Zoe Thomas, Monsieur Mangetout, Hugh McIlvanney, Chris Woodhead, Steve Boyd, Lucinda Kemeny, Jasper Gerard, Paul Driver, John Humphrys, Nicholas Hellen, Richard Brooks, Julie Earle-Levine, Ian Hawkey, Alex Clark, Christopher Morgan, David Leppard, Lynne Franks, Paul Durman, Tony Fearon, Paul Blackett, Jonathon Carr-Brown Health Correspondent, Dave Hannigan, Alicia Wyllie, Mark Edwards, Mark Stevenson, Vic Durrant, Adèle Collins, Dan May, Susan Clark, Nick Rodrigues, Veronica Hindley, Gabriella Gamini, Rob Berkeley, Hans Blix, Blower, Phil Baker, Hugo Barnacle, Thomas Quinn, Christina Lamb, Victoria O'Brien, Lois Rogers, Raymond Keene, C L, Dominic Lutyens, David Cracknell, Senay Boztas, Cosmo Landesman, Marie Colvin, John Nichols, Diana Wright, Stephen Jones, Dr Evan Harris MP, Emma Johns, Dominic O'Connell, Brian Deer, Uzi Mahnaimi, Nick Cain, Louise Armitstead, Alan Glanville, Stephen Bleach, Peter Lloyd, Natalie Graham, Keith Cameron, Chris Harris, Caroline Donald, Ian Coxon, Nick Rennison, Glenn Dimelow, Jessica Brinton, Barry Mason, David Walsh, Ian Critchley, Richard Caseby Managing Editor, Ivo Tonnant, Helen Brown, Trevor Lewis, Colin McDowell, John Millward, Jonathan Austin, D Riley, Bryan Appleyard, Stephen Armstrong, John Elliott, Burlington Bertie, Martyn Piper, S Young, Roland White, Richard Woods, N T Shepherd, Shane Watson, M J Gleeson, John Waples-Deputy Business Editor, Rev Andrew Rumsey, Charlotte Hobson, Maurice Chittenden, Cindy Duffield, J Ince, Richard Brooks Arts Editor, Robin Lloyd, Richard Rae, Mark Franchetti, David Doe, Stewart Calligan, Jon Ungoed-Thomas, Ray Hutton, Jonathan Leake, Alistair Cooke, Leonie Barratt, Michael Sheridan, Amanda Craig, Clare Francis, John Harlow, Dileep Premachandran, Brian Smyth, Adrian Somerfield, Lesley Thomas, W L Gore Gore-Tex manufacturer, Dipesh Gadher, John Waples, Hunter Davies, Jeremy Hart, A A Gill, Ros Dodd, Heather Moore, Matthew Campbell, John Dennis, John Carey, Tim King, Mary Braid, Nick Fielding, Philip Pangalos, Stephen Pettitt, Joy Lovejoy, Andrew Lycett, Jonathan Leake Science Editor, Malcolm Gough, Claudia Croft, Rajiv Radhakrishnan, Sally Kinnes, Naomi Caine, Nigel Powell, David Wickers, Dr Niall McCarthy, Richard Buckley, Brian Doogan, Ben Dowell, Minette Marrin, John Aizlewood, Kate Battersby, Mark Hodson, Andrew Frankel, Graham Norwood, J P, Joe Lovejoy, Jonathan Futrell, Theo Richmond, David Budworth, Anne Baker, Hugh Pearman, Andrew Davidson, Dan Cairns, Julie Leonard, Stewart Mitchell, Peter Myers, Philip Lyons, Mike Hammond, Andy Campden, David Smith Economics Editor, Philip Pullman, Mark Thomas, Tom Deveson, Susannah Price, Sarah Baxter, Helen Vandevelde, M Darby, Julia Langdon, David Robertson, Matthew Goodman, Fiona Henderson, Simon Howard, Greg LeMond, Tom Bower, Jason Dawe, Dominic Rushe, Julie Deegan, Karen Robinson, Trevor Phillips,
... throne in 1066 A Story Teller's Might: Christopher Paolini wasn't … Mazda6-Soul of a Sports Car ...
2004 - Gale Group | Sunday Times HA GDA
Graeme J. Hankey, Susanna R. Stevens, Jonathan P. Piccini, Yuliya Lokhnygina, Kenneth W. Mahaffey, Jonathan L. Halperin, Manesh R. Patel, Günter Breithardt, Daniel E. Singer, Richard C. Becker, Scott D. Berkowitz, John F. Paolini, Christopher C. Nessel, Werner Hacke, Keith A.A. Fox, Robert M. Califf,
Background and Purpose— Intracranial hemorrhage (ICH) is a life-threatening complication of anticoagulation. Methods— We investigated the rate, outcomes, and predictors of ICH in 14 264 patients with atrial fibrillation from Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). Cox proportional hazards modeling was used. Results— During 1.94 years (median) of follow-up, 172 patients ( ...
Tópico(s): Acute Ischemic Stroke Management
2014 - Lippincott Williams & Wilkins | Stroke
Andrew Robson, Carl Mortished International Business Editor and James Doran, Richard Mottram (Permanent Secretary Department), Robert Dawson Scott, Robert Cole, Andrew Pierce, DJM, Neelam Verjee, Alexandra Frean, Sarah Potter, Simon Barnes, Vivienne Nathanson (Head of Science and Ethics BMA), Paul Hoggart, Mark Souster, Martin Richards, Richard Hobson, Richard Harrison, Richard Ford and Frances Gibb, Nicola Venning, Philip Howard, Simon Birch, Jonny Wilkinson, Christine Seib, Ivo Tennant Totesport League, James Bone, James Ducker, Nic Hopkins, Lorna Blackwood, Graham Reardon, Liz Hodgkinson, Richard Irving, Catherine Riley Property Editor, Carl Mortished, Patrick Kidd, Martin Aston, Sam Marlowe, John Bungey, Richard Willis, Kevin Eason, Geoff Brown, Pat Gibson, David McVay, DH, Valerie Elliott, Donald Hutera, Augus MacLeod and Alan Hamilton, Tom Bawden, Steve Bird, Alex Yeats, Ian Hoyle, Dominic Walsh, Steven Johnson, Norman Harris, Tim Reid, Eleanor Goldsworthy, Dan Sabbagh, Richard Ford Home Correspondent, Alan Hamilton, Anthony Browne Brussels Correspondent, Jenny MacArthur, MS, Jayne Dowle, David Hands, John F. W. Priestman, Helen Rumbelow, Matt Dickinson Chief Football Correspondent, Richard Turner, Salah Al-Shaikhly, Tim Teeman, Caroline Merrell Banking Correspondent, MB, David Thomas, Daniel McGrory, Oliver Kay, Michael J. Hendrie Astronomy Correspondent, Gerard Baker, Keith Downer, Ross Clark, Martin Johnson, Neil Harman, John Westerby, Rick Broadbent, Chris Smith, Pete Paphides, Daniel McGrory and Michael Theodoulou, Simon de Bruxelles, Jeremy page, Rob Wright, Geoffrey Dean, Stephen Farrell and Zahid Hussain, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Raymond Keene, Susan Bertram, Peter Riddell Political Briefing, Neville Scott, Martin Garrod, Chris Campling, Bronwen Maddox, Cathy Harris, Roger Foord, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, John Carr, David Mattin, Clarissa Dickson Wright, Gabriel Rozenberg Economics Reporter, David Hands Rugby Correspondent, Tony Cascarino, Christine Seib and James Doran, Geoff Carr, Paul Simons, Anna Frame, Tim Reid and Jacqui Goddard, Liz Scott, Steve Jelbert, Alan Lee Racing Journalist of the Year, Nick Szczepanik, Joe Bolger Stock Markets, Philip Webster Political Editor, Giles Whittell, Mel Webb, Ian Johns, Ashling O'connor, Graham Searjeant Financial Editor, Mike Rosewell, George Caulkin, Francis Hamlyn, Russell Jenkins, Ben MacIntyre, Richard Beeston, Brian Clarke, David Charter Chief Political Correspondent, Philip Webster, Jacqui Goddard, David Sinclair, Martin Waller, Nigel Hawkes Health Editor, Dr Thomas Stuttaford Medical briefing, Stuart Birch, Dr Thomas Stuttaford, Stephen Dalton, Leo Lewis, Richard Morrison, Anthony Browne Europe Correspondent, Deb Atkinson, SJ, Rajeev Syai and Ben Webster, Sebastian Smith, Olav Bjortomt, Peter Robinson, Jenny Davey, Phill Gordon, Richard Atack, Jane Macartney, Sam Lister Health Correspondent, Patience Wheatcroft, Peter Klinger, Ross Anderson, Christopher Irvine, Raekha Prasad, Damian Barr, Anthony Jury,
... Downing has to settle for third behind pacy Paolini Cycling Hampshire warm up for final in comfort ... Fanfare Bristol Hodgson Shuns his Poster Boy Image Christopher Irvine finds the Sale fly half keen to ...
2005 - Gale Group | TDA
Jonathan L. Halperin, Graeme J. Hankey, Daniel Wojdyla, Jonathan P. Piccini, Yuliya Lokhnygina, Manesh R. Patel, Günter Breithardt, Daniel E. Singer, Richard C. Becker, Werner Hacke, John F. Paolini, Christopher C. Nessel, Kenneth W. Mahaffey, Robert M. Califf, Keith A.A. Fox,
Background— Nonvalvular atrial fibrillation is common in elderly patients, who face an elevated risk of stroke but difficulty sustaining warfarin treatment. The oral factor Xa inhibitor rivaroxaban was noninferior to warfarin in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). This prespecified secondary analysis compares outcomes in older and younger patients. Methods and ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2014 - Lippincott Williams & Wilkins | Circulation
Shaun G. Goodman, Daniel Wojdyla, Jonathan P. Piccini, Harvey D. White, John F. Paolini, Christopher C. Nessel, Scott D. Berkowitz, Kenneth W. Mahaffey, Manesh R. Patel, Matthew W. Sherwood, Richard C. Becker, Jonathan L. Halperin, Werner Hacke, Daniel E. Singer, Graeme J. Hankey, Günter Breithardt, Keith A.A. Fox, Robert M. Califf,
This study sought to report additional safety results from the ROCKET AF (Rivaroxaban Once-daily oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation). The ROCKET AF trial demonstrated similar risks of stroke/systemic embolism and major/nonmajor clinically relevant bleeding (principal safety endpoint) with rivaroxaban and warfarin. The risk of the principal safety and component bleeding endpoints with rivaroxaban versus ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2013 - Elsevier BV | Journal of the American College of Cardiology
Patrick O. McKeon, Gabriele Paolini, Christopher D. Ingersoll, D. Casey Kerrigan, Ethan N. Saliba, Bradford C. Bennett, Jay Hertel,
Objective: To examine the effects of a four-week balance training programme on ankle kinematics during walking and jogging in those with chronic ankle instability. A secondary objective was to evaluate the effect of balance training on the mechanical properties of the lateral ligaments in those with chronic ankle instability. Design: Randomized controlled trial. Setting: Laboratory. Subjects/patients: Twenty-nine participants (12 males, 17 females) with self-reported chronic ankle instability were ...
Tópico(s): Tendon Structure and Treatment
2009 - SAGE Publishing | Clinical Rehabilitation
Graeme J. Hankey, Susanna R. Stevens, Jonathan P. Piccini, Yuliya Lokhnygina, Kenneth W. Mahaffey, Jonathan L. Halperin, Manesh R. Patel, Günter Breithardt, Daniel E. Singer, Richard C. Becker, John F. Paolini, Christopher C. Nessel, Werner Hacke, Keith A.A. Fox, Robert M. Califf,
Background: For patients with atrial fibrillation (AF) at moderate to high risk of stroke, oral anticoagulation reduces the risk of ischemic stroke but may increase hemorrhagic stroke and offset the intended benefits in certain individuals. Identifying individuals with AF at high risk of stroke who are likely to have an intracranial hemorrhage (ICH) if treated with anticoagulants remains a challenge. Methods: We investigated factors associated with ICH in 14,264 patients with nonvalvular AF randomized ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2012 - Lippincott Williams & Wilkins | Stroke
Haben Yhdego, Christopher Paolini, Michel Audette,
Real-time fall detection using a wearable sensor remains a challenging problem due to high gait variability. Furthermore, finding the type of sensor to use and the optimal location of the sensors are also essential factors for real-time fall-detection systems. This work presents real-time fall-detection methods using deep learning models. Early detection of falls, followed by pneumatic protection, is one of the most effective means of ensuring the safety of the elderly. First, we developed and compared ...
Tópico(s): Balance, Gait, and Falls Prevention
2023 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Subrata Bhattacharjee, Wynn Tran, Matthew Laue, Christopher Paolini, Yuji Nakamura,
Tópico(s): Flame retardant materials and properties
2014 - Elsevier BV | Proceedings of the Combustion Institute
Subrata Bhattacharjee, Mathew Bundy, Christopher Paolini, Gaurav Rameshbhai Patel, Wynn Tran,
One of the challenges in the experimental study of flame spread is that, even if the flame spreads at a steady rate, the propagating flame creates an unsteady phenomenon with respect to the laboratory frame of reference. As a result, only a few studies have been done where the detailed flame structure has been experimentally measured along with the spread rates. In this work, we demonstrate the feasibility of a new flame spread apparatus that moves the fuel in the opposite direction of the flame ...
Tópico(s): Combustion and Detonation Processes
2012 - Elsevier BV | Proceedings of the Combustion Institute
Subrata Bhattacharjee, Shuhei Takahashi, Kazunori WAKAI, Christopher Paolini,
Numerical analysis and scale analysis are combined in a novel manner in this work to develop closed-form expressions for flame geometry in opposed-flow flame spread over condensed fuels. A scale analysis is used to relate different geometric attributes to appropriate non-dimensional parameters. A comprehensive numerical model is then used to generate a large set of numerical data for flame height, flame length, and pyrolysis length as functions of different fuel and oxidizer parameters for flame ...
Tópico(s): Combustion and Detonation Processes
2010 - Elsevier BV | Proceedings of the Combustion Institute
Subrata Bhattacharjee, Christopher Paolini, Wynn Tran, Jeanie Ray P. Villaraza, Shuhei Takahashi,
The flame structure of a downward flame spreading over thermally thin cellulose in a normal gravity quiescent environment is investigated in this work. A novel experimental set up called the flame stabilizer is used to arrest the motion of the flame by moving the fuel sample. The frozen flame is probed by K-type fine-wire thermocouples and a non-dispersive infrared radiation (NDIR) sensor with force induction to produce the experimental temperature and CO2 concentration fields. A two dimensional, ...
Tópico(s): Advanced Combustion Engine Technologies
2014 - Elsevier BV | Proceedings of the Combustion Institute
Dora L. Vallejo-Ardila, Katrina A. Walsh, Theodora Fifis, Rita Paolini, Georgios Kastrappis, Christopher Christophi, Marcos V. Perini,
Background It is now recognized that many anticancer treatments positively modulate the antitumor immune response. Clinical and experimental studies have shown that inhibitors of the classical renin–angiotensin system (RAS) reduce tumor progression and are associated with better outcomes in patients with colorectal cancer. RAS components are expressed by most immune cells and adult hematopoietic cells, thus are potential targets for modulating tumor-infiltrating immune cells and can provide a mechanism ...
Tópico(s): Cancer, Stress, Anesthesia, and Immune Response
2020 - BMJ | Journal for ImmunoTherapy of Cancer
... recently read of nineteen-year-old American novelist Christopher Paolini. Mr. Paolini, who wrote his bestselling novel Eragor9 ...
Tópico(s): Global Educational Reforms and Inequalities
2005 - Routledge | Texas international law journal
Amy W. Shaheen, Eileen Ciesco, Kevin Johnson, Greg Kuhnen, Christopher Paolini, Gary Gartner,
Abstract Equitable distribution of vaccines is necessary to ensure those at highest risk of illness are protected from COVID-19 (coronavirus disease 2019). Unfortunately, there is significant evidence that vaccines have not been reaching the most vulnerable. At our large hospital system, we created interactive online tools to measure and visualize equitability of vaccine administrations and to help stakeholders identify populations at highest risk within state-designated eligible vaccine groups. ...
Tópico(s): Diabetes Management and Research
2021 - Oxford University Press | Journal of the American Medical Informatics Association
... Chusfani in translating English into Indonesia language of Christopher Paolini‘s Novel of “Inheritance” as well as the ... Chusfani in translating English into Indonesia language of Christopher Paolini‘s Novel of “Inheritance”. This is descriptive qualitative ... Chusfani in translating English into Indonesia language of Christopher Paolini‘s Novel of “Inheritance”
Tópico(s): Second Language Acquisition and Learning
2016 - IAIN Salatiga | Register Journal
Kinjal Gala, Paul David Bryden, Christopher Paolini, Matthew Wang, Albena Mihovska, Mahasweta Sarkar,
A leading cause of physical injury sustained by elderly persons is the event of unintentionally falling. A delay between the time of fall and the time of medical attention can exacerbate injury if the fall resulted in a concussion, traumatic brain injury, or bone fracture. The authors present a solution capable of finding and tracking, in real-time, the location of an elderly person within an indoor facility, using only existing Wi-Fi infrastructure. This paper discusses the development of an open ...
Tópico(s): IoT Networks and Protocols
2020 - IGI Global | International Journal of Interdisciplinary Telecommunications and Networking
Christopher Paolini, Subrata Bhattacharjee,
W3C standardized Web Services are becoming an increasingly popular middleware technology used to facilitate the open exchange of chemical data. While several projects in existence use Web Services to wrap existing commercial and open-source tools that mine chemical structure data, no Web Service infrastructure has yet been developed to compute thermochemical properties of substances. This work presents an infrastructure of Web Services for thermochemical data retrieval. Several examples are presented ...
Tópico(s): Various Chemistry Research Topics
2008 - American Chemical Society | Journal of Chemical Information and Modeling
Katrina A. Walsh, Georgios Kastrappis, Theodora Fifis, Rita Paolini, Christopher Christophi, Marcos V. Perini,
Most patients with colorectal cancer (CRC) develop metastases, predominantly in the liver (CLM). Targeted therapies are being investigated to improve current CLM treatments. This study tested the effectiveness of SAR131675, a selective VEGFR-3 tyrosine kinase inhibitor, to inhibit CLM in a murine model. Following intrasplenic induction of CLM, mice were treated daily with SAR131675. Tumor growth and immune infiltrates into tumor and liver tissues were assessed at 10-, 16- and 22-days post tumor induction ...
Tópico(s): Cancer Cells and Metastasis
2022 - Multidisciplinary Digital Publishing Institute | Cancers
Somayeh Komeylian, Christopher Paolini, Mahasweta Sarkar,
The open nature of the wireless medium leads to the growing technical literature on solutions and techniques for increasing the privacy and security of a wireless communication channel. This work focuses on implementing the beamforming technique incorporated with a combination of MIMO-OFDM techniques for increasing physical layer security in the downlink of a wireless communication channel. The rectangular antenna array has been employed at the Tx side of an MIMO-OFDM channel with two orthogonal ...
Tópico(s): Cooperative Communication and Network Coding
2023 - Springer International Publishing | Lecture notes in networks and systems
Christopher Paolini, Subrata Bhattacharjee, William F. Coleman, Edward W. Fedosky,
Analysis of chemical equilibria is a topic covered in both undergraduate and graduate courses such as physical chemistry, chemical thermodynamics, and engineering thermodynamics. Manual calculation of problems that require a student to solve for species concentrations, partial pressures, or mole fractions usually involves the method of equilibrium constants. Exercises in homework assignments or in-class examinations are frequently limited to reactions that involve no more than four gas-phase species ...
Tópico(s): Various Chemistry Research Topics
2010 - American Chemical Society | Journal of Chemical Education
Lindsay K. Drewes, Patrick O. McKeon, Gabriele Paolini, Patrick O. Riley, D. Casey Kerrigan, Christopher D. Ingersoll, Jay Hertel,
Kinematic patterns during gait have not been extensively studied in relation to chronic ankle instability (CAI).To determine whether individuals with CAI demonstrate altered ankle kinematics and shank-rear-foot coupling compared with controls during walking and jogging.Case control.Motion-analysis laboratory.7 participants (3 men, 4 women) suffering from CAI (age 24.6 +/- 4.2 y, height 172.6 +/- 9.4 cm, mass 70.9 +/- 8.1 kg) and 7 (3 men, 4 women) healthy, matched controls (age 24.7 +/- 4.5 y, height 168.2 +/- 5.9 cm, mass ...
Tópico(s): Sports injuries and prevention
2009 - Human Kinetics | Journal of Sport Rehabilitation
Shaun G. Goodman, Daniel Wojdyla, Harvey D. White, Jonathan P. Piccini, John F. Paolini, Christopher C. Nessel, Kenneth W. Mahaffey, Manesh R. Patel, Richard C. Becker, Jonathan L. Halperin, Werner Hacke, Daniel E. Singer, Graeme J. Hankey, Günter Breithardt, Keith A.A. Fox, Robert M. Califf,
Background: AF is associated with increased ischemic stroke risk. Oral anticoagulation reduces this risk, but there is often suboptimal use of stroke prophylaxis among AF patients, which may be due to challenges in risk stratification for bleeding. Methods: We investigated factors associated with bleeding in 14,264 pts with nonvalvular AF randomized to rivaroxaban or dose-adjusted warfarin in ROCKET AF. Endpoints of interest were ISTH-defined major bleeding events, intracranial and fatal bleeding. ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2011 - Lippincott Williams & Wilkins | Circulation
Jared Brzenski, Christopher Paolini, José E. Castillo,
Large scale geophysical modeling uses high performance computing systems to expedite the solutions of very large, complex systems. High disk latencies, low IOPS, and low read/write data transfer rates are relegating many numerical simulations to I/O bound jobs, where the run time is bound not by CPU rate, but by I/O rate. In this paper we seek to improve the I/O of two geophysical modeling applications and take full advantage of the parallel nature of the programs, as well as the file management ...
Tópico(s): Parallel Computing and Optimization Techniques
2021 - Elsevier BV | Parallel Computing
Keith A.A. Fox, Jonathan P. Piccini, Daniel Wojdyla, Richard C. Becker, Jonathan L. Halperin, Christopher C. Nessel, John F. Paolini, Graeme J. Hankey, Kenneth W. Mahaffey, Manesh R. Patel, Daniel E. Singer, Robert M. Califf,
Patients with non-valvular atrial fibrillation (AF) and renal insufficiency are at increased risk for ischaemic stroke and bleeding during anticoagulation. Rivaroxaban, an oral, direct factor Xa inhibitor metabolized predominantly by the liver, preserves the benefit of warfarin for stroke prevention while causing fewer intracranial and fatal haemorrhages.We randomized 14 264 patients with AF in a double-blind trial to rivaroxaban 20 mg/day [15 mg/day if creatinine clearance (CrCl) 30-49 mL/min] or ...
Tópico(s): Acute Ischemic Stroke Management
2011 - Oxford University Press | European Heart Journal
Manesh R. Patel, Kenneth W. Mahaffey, Jyotsna Garg, Guohua Pan, Daniel E. Singer, Werner Hacke, Günter Breithardt, Jonathan L. Halperin, Graeme J. Hankey, Jonathan P. Piccini, Richard C. Becker, Christopher C. Nessel, John F. Paolini, Scott D. Berkowitz, Keith A.A. Fox, Robert M. Califf,
The use of warfarin reduces the rate of ischemic stroke in patients with atrial fibrillation but requires frequent monitoring and dose adjustment. Rivaroxaban, an oral factor Xa inhibitor, may provide more consistent and predictable anticoagulation than warfarin.
Tópico(s): Cardiac Arrhythmias and Treatments
2011 - Massachusetts Medical Society | New England Journal of Medicine
Produção Nacional
Revisado por pares
Graeme J. Hankey, Manesh R. Patel, Susanna R. Stevens, Richard C. Becker, Günter Breithardt, Antonio Carolei, Hans‐Christoph Diener, Geoffrey A. Donnan, Jonathan L. Halperin, Kenneth W. Mahaffey, Jean‐Louis Mas, Ayrton Roberto Massaro, Bo Norrving, Christopher C. Nessel, John F. Paolini, Risto O. Roine, Daniel E. Singer, Ka Sing Wong, Robert M. Califf, Keith A.A. Fox, Werner Hacke,
In ROCKET AF, rivaroxaban was non-inferior to adjusted-dose warfarin in preventing stroke or systemic embolism among patients with atrial fibrillation (AF). We aimed to investigate whether the efficacy and safety of rivaroxaban compared with warfarin is consistent among the subgroups of patients with and without previous stroke or transient ischaemic attack (TIA).In ROCKET AF, patients with AF who were at increased risk of stroke were randomly assigned (1:1) in a double-blind manner to rivaroxaban ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2012 - Elsevier BV | The Lancet Neurology
Jingxiao Tian, Patrick P. Mercier, Christopher Paolini,
This work focuses on the development and manufacturing of a wireless, wearable, low-power fall detection sensor (FDS) designed to predict and detect falls in elderly at-risk individuals. Unintentional falls are a significant risk in this demographic, often resulting from diminished physical capabilities such as reduced hand grip strength and complications from conditions like arthritis, vertigo, and neuromuscular issues. To address this, we utilize advanced low-power field-programmable gate arrays ( ...
Tópico(s): Balance, Gait, and Falls Prevention
2024 - Elsevier BV | Smart Health