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Jornais Acesso aberto

James Landale, Mark Ridley, Widget Finn, Andrew Burrows Law Commission, Paul Heiney, Gabriel Josipovici, Nick Nuttall Environment Correspondent, Ronald T. Flowe, Robin Pedler, Adrian Lee, T. L. Shanson, Magnus Linklater, Robert Miller and Karen Zagor, Richard Thomson, Mark Souster, Charles Bremner and Michael Hornsby, Agriculture Correspondent, Janet Bush, Economics Correspondent, Harvey Elliott, Murray Naylor, Philip Howard, Carol Midgley, Hilary Finch, Carl Mortished, Morag Preston, Roger Maynard, Stewart Tendler, Crime Correspondent, Geoff Brown, Robert Sheehan, Bridge Correspondent, Robert Miller, Hammond Smith, Martin Fletcher, Pat Gibson, Ruth Gledhill, Religion Correspondent, Malcolm Bradbury, John O'leary Education Editor, John Bryant, Iain A. T. Donald solicitor, Steve Keenan, Roger Bray, Ann Scanlon, Peter Ball, Eric Evans, Debra Craine, Michael Sissons, Philip Donald, Raymond Keene Chess Correspondent, Richard Evans, Racing Correspondent, Rob Hughes Football Correspondent, Martin Barrow, Dalya Alberge Arts Correspondent, Pat Stacy Waddy, Michael Evans, Defence Correspondent, Rodney Milnes, Jill Sherman Chief Political Correspondent, Robert Nye, Jenny MacArthur, Robert Bruce, Michael Clark, Jeremy Laurance, Health Correspondent, James Landale Political Reporter, Anatole Kaletsky, Quentin Letts, David Hands, Charles Bremner, John O'leary, Peter Barnard, Philip Bassett, Industrial Editor, Caroline Greenwood, Peter Mahaffey, D. J. Skinner, Francis Wilford-Smith, Philip J. Wadsworth, Paul Durman, Anne Ashworth and Robert Miller, Michael Theodoulou, Sydney Friskin, Anthony Parsons, Glencairn Balfour-Paul, James Craig, Ivor Lucas, Michael Weir, John Hopkins, Gillian Bowditch, John Higgins, Gillian Bowditch, Scotland Correspondent, David Powell Athletics Correspondent, Michael Cassidy Chairman, Herman Ouseley, Chairman, Raymond Keene, Jonathan Prynn, Christine Buckley, Peter Davalle, Alan Lee, Cricket Correspondent, Emma Wilkins, John Grigg, Richard Wetherell, K. Culley Chairman, P. H. S, Paul Wilkinson, L. M. Stanley, Richard Evans, Nigel Hawkes, Oliver Holt, Richard Owen, Roger Boyes, Oliver August, Allan Mallinson, Andrew Pierce Political Correspondent, Kate Alderson, Robert Langford, David Hands Rugby Correspondent, Julian Muscat, Adam Fresco, John Allison, Jill Sherman and Philip Webster, Christopher Thomas, William Rees-Mogg, David Churchill, Christopher Walker, Mel Webb, Matthew Parris, Graham Searjeant Financial Editor, Michael Hornsby, Peter Riddell, Ben MacIntyre, Lesia Rudakewich, Tony Dawe, Richard Beeston, Stephen Farrell and Joanna Bale, Michael Dynes, Gerard Noel, David Walker, Fraser Nelson, Michael Binyon, Diplomatic Editor, Michael Horsnell, N. Parry, P. Irvine, Nigel Hawkes Science Editor, Benedict Nightingale, Dr Thomas Stuttaford, Marianne Curphey, D. M. Penton, Jack Bailey, Frances Gibb, Arthur Leathley, David Maddock, Robert Whymant, Matthew Bond, Alan Hamilton and Emma Wilkins, John Thaxter, Tom Bower,

... Systems ETC Howgate Sable & Partners Executive Search and… Chronos Richardson Citymax Howgate Sable & Partners Executive Search and… ...

1996 - Gale Group | TDA

Carta Acesso aberto Revisado por pares

Richard Robinson,

... to light is built upon the cellular clock. CHRONO negatively regulates circadian oscillations by directly interacting with ... genes, regulating their transcription. Both groups rename Gm129 “Chrono” for either “computationally highlighted” or “ChIP-derived” repressor of network oscillator. The CHRONO protein interacted with BMAL1 and several other known ... a phase opposite that of BMAL1. Knocking out Chrono led to an increase in the behavioural circadian ... other core clock components. By selectively knocking out Chrono in mouse hypothalamus (the site of whole-body ...

Tópico(s): Circadian rhythm and melatonin

2014 - Public Library of Science | PLoS Biology

Jornais Acesso aberto

L. Gastine, A. De Letamendi,

... of contents: Sommaire. Essay: Les Nouveautés Photographiques Les Chronos De Poche, Chronique Besogne Nécessaire, Obtention Des Négatifs, ...

1900 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Daniel Keppeler, Ricardo Martins Merino, David López de la Morena, Burak Bali, Antoine Huet, Anna Gehrt, Christian Wrobel, Swati Subramanian, Tobias Dombrowski, Fred Wolf, Vladan Rankovic, Andreas Neef, Tobias Moser,

... stimulation of the auditory pathway by targeting-optimized Chronos Daniel Keppeler orcid.org/0000-0002-2638-8731 ... off. Here, we biophysically characterized the fast channelrhodopsin Chronos and revealed a deactivation time constant of less ... we improved its trafficking to the plasma membrane (Chronos-ES/TS). Following efficient transduction of SGNs using ... conclusion, efficient virus-mediated expression of targeting-optimized Chronos-ES/TS achieves ultrafast optogenetic control of neurons. ... improved the fast gating blue-light activated channelrhodopsin Chronos. Employing the potent viral vector AAV-PHP.B ...

Tópico(s): Light effects on plants

2018 - Springer Nature | The EMBO Journal

Jornais Acesso aberto

Tunku Varadarajan, Jon Ashworth, Raymond Snoddy Media Editor, Gabriel Josipovici, Srikumar Sen, boxing correspondent, David Whitaker, Julian Muscat, Tennis Correspondent, Lucy Lawrence, Sarah Potter, Frances Gibb and Richard Ford, Magnus Linklater, Jan Morris, Gabriella Gamini, South America Correspondent, Samuel Jacob, Economist, Roger Boyes and Charles Bremner, Mark Souster, Richard Hobson, George Dobry (Chairman), Stewart Maugham, Raymond Snoddy, Media Editor, James Landale, Political Reporter, Philip Howard, David C. Askren, Hilary Finch, Stuart Barrow, Denis Young, Jeremy Kingston, Joanna Bale, James Bone, George Sivell, Paul Whittaker, Carl Mortished, Morag Preston, Stewart Tendler, Crime Correspondent, C. J. Ancliff, Geoff Brown, Philip Bassett Industrial Editor, Robert Sheehan, Bridge Correspondent, Marit Hargle, Joe Joseph, E. Preston, John Bryant, Valerie Elliott, Christopher Thomas, South Asia Correspondent and James Bone, Janet Bush, Economics Editor, Pugh & Way, Ruth Gledhill, O. S. Knowles (Acting Permanent Secretary), Raymond Keene Chess Correspondent, John Street, Rachel Kelly, Richard Evans, Racing Correspondent, Martin Barrow, Peter Waymark, Michael Evans, Defence Correspondent, Julia Hausermann (President), Alan Hamilton, Rodney Milnes, Rachel Kelly, Property Correspondent, Robert Bruce, Michael Clark, Vernon Bogdanor, James Bone and Michael Theodoulou, David Hands, Martin Fletcher Chief Ireland Correspondent, Peter Barnard, George Foulkes, Derwent May, Jasper Gerard, Vivienne Michael, Director, Clive Studd (Director), Russell Kempson, Daniel McGrory, Paul Durman, Claire Messud, Nick Nuttall and Rachel Kelly, Sylvia A. H. Ray, Martyn Palmer, Barry Millington, Ian Brunskill, Simon de Bruxelles, Richard Miles, Banking Correspondent, John Higgins, Oliver Impey, Matt Dickinson, Alix Ramsay, Paul Wilkinson, Michael Wood (Director), Bronwen Maddox, Jill Sherman, Richard Owen, Damian Whitworth, Susan Gray, John Carr, Oliver August, Andrew Pierce Political Correspondent, Stewart Tendler, David Hands Rugby Correspondent, Adam Fresco, Nicholas Wood, Valerie Elliott, Whitehall Editor, John Allison, R. W. Johnson, Nicholas Bethell, William Rees-Mogg, John Goodbody, John E. Strafford (Chairman), Jason Nisse, Christopher Walker, Chris Parker, Simon De Bruxelles, Andrew Pierce and Philip Webster, Jason Nissé, Des Dearlove, Kevin McCarra, Matthew Parris, Chris McGrath, L. L. Blake, Michael Hornsby, Mark Clements, Peter Riddell, Ben MacIntyre, Ian Brodie, Jason Cowley, Fraser Nelson, Michael Binyon, Diplomatic Editor, Mark Henderson, Kevin Eason and Roger Boyes, Chris Ayres, Martin Waller, Nigel Hawkes Science Editor, Marianne Curphey Insurance Correspondent, Benedict Nightingale, Dr Thomas Stuttaford, Andrew Turner, Marianne Curphey, Arthur Leathley, David Maddock, Richard Miles Banking Correspondent, Thomas Stuttaford, Colin McQuillan, Isobel Sharp, Christopher Irvine, Richard Harden,

... House of Lords Fenner rises to a record Chronos loss hits Staveley Volex awaits Ericsson role Dickie ...

1997 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Deepika Reddy, Taimur T. Shah, Tim Dudderidge, Stuart McCracken, Manit Arya, Chris Dobbs, Mark Emberton, Francesca Fiorentino, Emily Day, A Toby Prevost, John Staffurth, Matthew R. Sydes, Mathias Winkler, Hashim U. Ahmed,

... Research Outcomes of Novel Surgery in prostate cancer (CHRONOS) will compare the cancer control of these two strategies. CHRONOS is a parallel phase II RCT for patients ... clinician/patient decision, patients will enrol into either CHRONOS-A or CHRONOS-B. CHRONOS-A will randomize patients to either radical treatment or FT. CHRONOS-B is a multi-arm, multistage RCT comparing ... plans to recruit and randomize 1190 patients into CHRONOS-A and 1260 patients into CHRONOS-B. Primary outcome in CHRONOS-A is progression- ...

Tópico(s): Cancer, Lipids, and Metabolism

2020 - Elsevier BV | Contemporary Clinical Trials

Jornais Acesso aberto

... II, Aegiochus N. G. Derivatio: …, a Son of Chronos, Among the Zoological Collections of the Last Swedish ...

1885 - Gale Group | NCCO-STM 1of2

Artigo Acesso aberto Revisado por pares

Gerda K. Pot,

... researchers have incorporated research of biological temporal rhythms, chrono-biology, into nutrition research, and this novel area of nutrition research is called chrono-nutrition (Garaulet & Gómez-Abellán, 2014; St-Onge et al., 2017; Tahara & Shibata, 2013). Chrono-nutrition includes research into the distribution of energy ... published in Nutrition Bulletin discussing different aspects of chrono-nutrition, including sleep, breakfast consumption and time-restricted ... Ruddick-Collins et al., 2018). Other elements of chrono-nutrition such as meal regularity, meal frequency and ...

Tópico(s): Sleep and related disorders

2021 - Wiley | Nutrition Bulletin

Jornais Acesso aberto

Helen Johnstone, Nick Nuttall Environment Correspondent, Robert Cole, Richard Ellis, Andrew Pierce, John White, Sally Brock, James Moore, Frances Gibb Legal Editor, Simon Barnes, Lord Justice Robert Walker, George Pendle, Robert Thicknesse, Claire McDonald, Mary IIiff, Richard Hobson, Inigo Gilmore, Ivo Tennant, Jane Bolton, Lord Justice Chadwick, Susan Emmett and Lea Paterson, Jeremy Kingston, Alexandra Frean Social Affairs Correspondent, Marilyin Kingwill, Mary Wilson, Carl Mortished, Roger Maynard, Kevin Eason, Thomas Dunne, James Eve, Geoff Brown, Sonia Purnell, Joe Joseph, Giles Coren, Anne Efowcs Williams, Pat Gibson, Paul Fitzpatrick, Jason Allardyce, Stewart Tendler Crime Correspondent, David Charter Education Correspondent, Dominic Walsh, Alix Ramsay Tennis Correspondent, Audrey Magee Ireland Correspondent, Dalya Alberge Arts Correspondent, Jonathan Romain, Richard Ford Home Correspondent, Caroline Marrell Banking Correspondent, Richard Ford Home Correspondent and Russell Kempson, Alan Hamilton, Mark Inglefield, Dianna Wildman, Ana Urena, John O'Leary, Helen Rumbelow Medical Reporter, Amanda Copp, Roland Watson, Ralph Glasser, Sierra Leone, Katherine Bergen, Peter Barnard, Patience Wheatcroft Business Editor, James Doran City Correspondent, Lisa Jardine, Russell Kempson, Paula Hawkins, Mary Gold, Richard Cork, Jane Gordon, Amber Cowan, Claire Messud, David Lister, David Charter and Valerie Elliott, John Hopkins, Oliver Bernier, Alan Howard, Ronald Forrest, John Hopkins Golf Correspondent, Jonathan Redvers Harris, Rob Wright, Karen Homer, Chris MacGrath, Adam Jones, Paul Peachey, David Robinson, Clive Mathieson, John Russell Taylor, Paul Wilkinson, Caroline Merrell, F. F. Dajani, Melissa Kite, Chris Ayres Media Business Correspondent, Michaela Roberts, Chris Harris, Oliver Holt, Richard Owen, Robert Harding, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, Tola Awogbamiye, Roger Boyes, Peter Ackroyrl, George Ferguson, Karen Armstrong, Nick Hasell, Melanie Johnson, Philip August, David Hands Rugby Correspondent, A. S. Byatt, Martin Fletcher European Correspondent, Anne Ashworth, John Goodbody, Dave Browe, Giles Whittell, Philip Webster Political Editor, Alex O'Connell, Christopher Booker, Susang Sontag, Gerald Larner, Christine Webb, George Caulkin, Diana Britan, Alan Lee, Iain Finlayson, Juliet Barker, Ben MacIntyre, Colin MacQuillan, Sarah Jane Checkland, Richard Beeston Diplomatic Editor, Beryl M. Goldsmith, Jame Bone, Bianca Wordley, Paul Gilroy, Simon Jenkins, Tim Jones, Martin Waller, Chris Ayres, Marion MacGilvary, Alan Coren, Laura Peek, Benedict Nightingale, Edward Gorman Sailling Correspondent, Catherine Philips, Richard Beeston and Michael Evans, Carr-Lyons, Stanley Matchett, Sam Kiley, Alice Miles, Adam Sherwin, Alan Lee Racing Correspondent, Robert Whymant, Walter Hooper, Sally Patten, Roland Watson Chief Political Correspondent, Terence W. Wiseman, Anthony Howard, Gisbrough, Fraser Nelson Retail Correspondent, John Akehurst, David Kemp, Patience Wheatcroft, Christopher Irvine, Nicholas Jones, Susan Emmett,

... Dame de Paris 'this is a Very Different… Chronos Buildings No title A slice of history in ...

2000 - Gale Group | TDA

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

João Paulo Bonardi, Rodrigo dos Santos Pereira, Fernanda Brasil Daura Jorge Boos Lima, Leonardo Pérez Faverani, Geraldo Luiz Griza, Roberta Okamoto, Eduardo Hochuli‐Vieira,

... The aim of this study was to compare ChronOS (β-tricalcium phosphate), Bio-Oss, and their addition ... group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ChronOS and autogenous bone graft in a 1:1 ... 13,421.3 μm2 in group 5. Conclusions ChronOS combined with autogenous bone graft presented a behavior ... The aim of this study was to compare ChronOS (β-tricalcium phosphate), Bio-Oss, and their addition ... group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ...

Tópico(s): Periodontal Regeneration and Treatments

2017 - Elsevier BV | Journal of Oral and Maxillofacial Surgery

Jornais Acesso aberto

Marion McGilvary, Raymond Snoddy Media Editor, Helen Johnstone, Nick Nuttall Environment Correspondent, Oliver Holt Chief Sports Correspondent, Fred Redwood, Andrew Pierce, James Moore, Grace Bradberry, Adam Jones and David Lister, Simon Barnes, George Pendle, Michael Wale, Claire McDonald, Philip Webster Political Editor and Alan Hamilton, Jane Bolton, David Lovibond, Michael Binyon, Jeremy Kingston, Alex O'Connell and Elizabeth Judge, James Bone, Rachel Campbell-Johnston, Angela Mortimer, Ludovic Kennedy, Carl Mortished, Gail E. Lydford, Roger Maynard, Sarah Fazzio, Joe Joseph, Andrew Norfolk, Giles Coren, Pat Gibson, Paul Fitzpatrick, Thrasy Petropoulos, David Charter Education Correspondent, David Frith, Dominic Walsh, Richard Beeston Diplomatic Editor and Oliver August, Bobby Robson, Tim Reid, Dalya Alberge Arts Correspondent, Michael Mulvihill, Alan Hamilton, Robin Young, Mark Inglefield, Mike Rosewell Rowing Correspondent, Rodney Milnes, James Landale Political Correspondent, Helen Rumbelow Medical Reporter, Ron Sawdon, Katherine Bergen, Peter Barnard, Anthea Lawson, Tim Teeman, Patience Wheatcroft Business Editor, Caroline Merrell Banking Correspondent, Joanne Rule, Russell Kempson, Keith Wollaston, Daniel McGrory, Paul Armstrong, Jane Gordon, Richard Cork, David Lister, Peter Riddell On Politics, Matt Dickinson Football Correspondent, Jenny Booth, Karen Homer, Simon de Bruxelles, Geoffrey Dean, Richard Holmes, Malcolm Rifkind, Adam Jones, David Powell Athletics Correspondent, David Robinson, Clive Mathieson, Alexandra Frean and Melissa Kite, Andrew Roberts, Alix Ramsay, Elizabeth Judge and Alex O'Connell, Edgar Degas, David Elleray Whistleblower, Chris Ayres Media Business Correspondent, Jill Sherman, Erica Wagner, Roger Boyes, Nick Hasell, Robin Renwick, David Hands Rugby Correspondent, Julian Muscat, Nick Szczepanik, Anne Ashworth, Philip Webster Political Editor, Brian MacArthur, Tim Hames, David Hoppit, Paul McCann Media Correspondent, Kevin McCarra, Graham Searjeant Financial Editor, Anjana Ahuja, Christine Webb, Chris McGrath, Melissa Kite Political Reporter, Russell Jenkins, Iain Finlayson, Victoria Greenhalgh, Ian Brodie, Dave Knight, Richard Beeston Diplomatic Editor, Michael Dynes, Simon Jenkins, Martin Waller, Chris Ayres, Benedict Nightingale, Alyson Rudd, Richard Morrison, Chris D. Kelly, Alice Miles, Tom Baldwin Deputy Political Editor, Mike Mitchell, Miranda Ingram's, Sally Patten, Roland Watson Chief Political Correspondent, Jan Raath, Patience Wheatcroft, Alan Lee The Course Inspector, Arthur Leathley Transport Correspondent,

... Title Villars Berkshire Enborne Fare, Newbury No Title Chronos Buildings No Title Times 2 Homes Letting out ...

2000 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Fatin Hanani Mazri, Zahara Abdul Manaf, Suzana Shahar, Arimi Fitri Mat Ludin, Siti Munirah Abdul Basir,

This paper describes the development of an integrated chrono-nutrition weight reduction program and the evaluation of the attendance, retention, satisfaction and compliance towards the chrono-nutrition components among morning and evening chronotypes for ... needs assessments on the chronotypes’ dietary patterns and chrono-nutrition through a scoping review and integrating the chrono-nutrition components (temporal eating pattern, meal timing and ... of a feasibility study to evaluate the integrated chrono-nutrition weight reduction program (SLIMSHAPE™ Chrono). A total ...

Tópico(s): Sleep and related disorders

2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health

Jornais Acesso aberto

Sydenham, Michael F. O'donnell, W. B. Maxwell, Sir Josiah, James Agate, Sir Oliver Lodge, W. A. Norris, Lord Hugh Cecil M. P., Mr. Justice McCardie, B. F. W., G. Elliot Smith F. R. S., Mr. Armstrong, Sir Hamar Greenwood M. P., Sir F. Dicksee, Maitland Davidson, Henry Murray, Ex. C. S., Sir A. Chamberlain's Handshake, Sir Graham Bower K. C. M. G., T. C. Weatherhead, Sir Robert Newman M. P., K. C. B., Miss Silent, H. Maurice Relton, Dell Leigh, Francis Woodlock S. J., St. Albans, Horace G. Hutchinson, Frank Rutter, D. R. Gent, Philip Morrell, Mr. Lloyd George, G. H. Milner-Pugh, Miss Hudson, W. G. Walter, George Greenwood, H. F., Lord Wrenbury, Violet Tootal, Philip Guedalla, Ernest Newman, Sir Henry Rew, Rt. Hon. T. P. O'Connor P. C., M. P., Ralph Straus, Mr. Baldwin's, Charles Mallet, E. V. Lucas, J. Kingston Barton, Col. K. P. Vaughan-Morgan M. P., Herbert Hunter, W. H. Findon, Edmund Gosse, George Moore, George R. I., Roland Atkinson (" Sunday Times" Paris Correspondent), DeanInge, A. Ernest Whiting, Raphael Roche, Arnold Bennett, J. E. Newman, Sir J. Simon's, Richard Aldington, G. W. Thacker Major, Miss Cator, R. J. Barrett Financial Editor, J. Tyrwhitt-Walker, E. N., Edward Bensly, Yarborough, Filson Young, A. W. Newton, Charles C. Osborne, G. B. S., P. H. Ditchfield, F. A. Mackenzie, Edwin Chappell, George C. Stead, D. M. Stewart, M. I. Ryan, L. Van Vliet, B. P. T., Harold Cox,

... Terms Editor,"the Countryman": Beet-Sugar in England Chronos: Age of the World Grand Opera Books of ...

1927 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Petr Gál, Šimon Ondruš, Jan Škvařil, Miroslav Straka, Jiří Jochymek, Ladislav Plánka,

... diagnosis were treated by minimally invasive application of chronOs Inject.The aim of the study was to ... novel method based on filling the cyst with chronOs Inject, a synthetic biocompatible resorbable material. An alternative ... interventions were performed in 18 patients treated by chronOs Inject and 100% cyst healing without necessity of ... lesion, synthetic tricalcium phosphate in the form of chronOs granules was used, but without the possibility of ... invasive percutaneous application. As soon s the resorbable chronOs Inject became available, the minimally invasive method of ...

Tópico(s): Elbow and Forearm Trauma Treatment

2009 - Medical publishing house Galen | Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca

Artigo Revisado por pares

Nadir A. Aliyev, Nadir A. Aliyev,

... European countries. However, the effect of Valproate (depakine-chrono) on generalized anxiety disorder (GAD) has not been ... Each patient was randomized to receive either depakine-chrono (40 patients) for 6 weeks or matched placebo ( ... scale score. Response and side effects with depakine-chrono and placebo were compared by using analysis of ... subsequent assessment, leaving 74 patients (36 taking depakine-chrono and 38 taking placebo) in the valuables study group.Twenty six of the 36 depakine-chrono-treated participants responded by 6 weeks, versus six ...

Tópico(s): Bipolar Disorder and Treatment

2007 - Cambridge University Press | European Psychiatry

Revisão Acesso aberto Revisado por pares

David E. Blask, Steven M. Hill, Robert T. Dauchy, Shulin Xiang, Lin Yuan, Tamika Duplessis, Lulu Mao, Erin M. Dauchy, Leonard A. Sauer,

... David E. Blask, David E. Blask Laboratory of Chrono-Neuroendocrine Oncology Department of Structural and Cellular Biology, ... authorRobert T. Dauchy, Robert T. Dauchy Laboratory of Chrono-Neuroendocrine Oncology Department of Structural and Cellular Biology, ... by this authorErin Dauchy, Erin Dauchy Laboratory of Chrono-Neuroendocrine Oncology Department of Structural and Cellular Biology, ... authorLeonard A. Sauer, Leonard A. Sauer Laboratory of Chrono-Neuroendocrine Oncology Department of Structural and Cellular Biology, ...

Tópico(s): Dietary Effects on Health

2011 - Wiley | Journal of Pineal Research

Jornais Acesso aberto

THOMAS WAKLEY., FREDERICK NORTH., S. BARNEBY., E. M. L. MOSTYN, A SUFFERING CREDITOR., CHRONOS., PHILIPPIENSIS., CHARLES COOK., E. H. DESVIGNES.,

Classified Advertising: FOR BENGAL and CHINA, with leave to land passengers at Madras, and will positively sail on the 15th, [Advertisement.]-At the approaching ...

1836 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Akihiro Goriki, Fumiyuki Hatanaka, Jihwan Myung, Jae Kyoung Kim, Takashi Yoritaka, Shintaro Tanoue, Takaya Abe, Hiroshi Kiyonari, Katsumi Fujimoto, Yukio Kato, Takashi Todo, Akio Matsubara, Daniel B. Forger, Toru Takumi,

... clock genes is exhaustive. We have recently identified Chrono as a robustly cycling transcript through genome-wide ... E-box. Here, we explore the role of Chrono in cellular timekeeping. Remarkably, endogenous CHRONO occupancy around E-boxes shows a circadian oscillation antiphasic to BMAL1. Overexpression of Chrono leads to suppression of BMAL1–CLOCK activity in ... manner. In vivo loss-of-function studies of Chrono including Avp neuron-specific knockout (KO) mice display a longer circadian period of locomotor activity. Chrono KO also alters the expression of core clock ...

Tópico(s): Light effects on plants

2014 - Public Library of Science | PLoS Biology

Jornais Acesso aberto

Our Correspondent., Our Own Correspondent., FROM OUR SPECIAL CORRESPONDENT., JAMES DEWAR., ALEXR. FRANCIS, CHRONOS.,

Births. Marriages. Deaths. Classified Advertising: Notices, Horses, Carriages, & c., Partnerships, Investments, & c., Personal, & c., Royal Selters Water, Banks., ...

1894 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Hammad Mazhar, Toby Heyn, Arman Pazouki, Daniel Melanz, A Seidl, Aaron Bartholomew, Alessandro Tasora, Dan Negruţ,

... large scale parallel computing has been leveraged in CHRONO, a freely available C++ multi-physics simulation package. CHRONO is made up of a collection of loosely ... and visualization. This contribution provides an overview of CHRONO::Engine, CHRONO::Flex, CHRONO::Fluid, and CHRONO::Render, which are modules that can capitalize on ... parallel processors. Problems that can be tackled in CHRONO include but are not limited to granular material ...

Tópico(s): Dynamics and Control of Mechanical Systems

2013 - Copernicus Publications | Mechanical sciences

Revisão Revisado por pares

Fumiyuki Hatanaka, Toru Takumi,

... critical for proper behavioral, physiological, and molecular functions. CHRONO, a novel circadian clock gene, forms a complex ... other clock proteins and modulates the circadian machinery. CHRONO also interacts with histone deacetylase (HDAC) to modulate the epigenetic status of the transcriptional regulation. Chrono knockout mice display a longer period of circadian ... response. This paper reviews the molecular function of CHRONO with a focus on epigenetic regulation and speculates on the possible function of CHRONO in physiological processes.Key messagesChrono is a circadian ...

Tópico(s): Light effects on plants

2016 - Informa | Annals of Medicine

Artigo Acesso aberto Revisado por pares

Sant Saran,

... low-power, fast optogenetic control of firing of Chronos-expressing neurons has been presented. A three-state model for the Chronos photocycle has been formulated and incorporated in a ... 0.005 mW / mm2), the plateau current in Chronos exhibits a maximum. At 0.05 mW / mm2, ... ms) compared to ChR2 (∼350 ms). Ipeak in Chronos saturates at much shorter pulse widths (1775 pA ... irradiances and longer pulse widths compared to ChR2. Chronos exhibits an average maximal driven rate of over ... important to not only understand the photodynamics of Chronos and Chronos-expressing neurons but also to design ...

Tópico(s): Neural dynamics and brain function

2018 - SPIE | Neurophotonics

Artigo Revisado por pares

Nicole T. Allen,

Chronos is a traditionally marginalized term in rhetorical studies. Historically paired with kairos, chronos is commonly taken to refer to chronology, empty, ... I argue for a reconsideration and redefinition of chronos that pairs the term with a critical materialist theory of time as change, immanent temporalities. Chronos understood as an entanglement of immanent temporalities informs ... or synchronization, of multiple processes of change. Reconsidering chronos makes room for investigating time-related texts, like ‘ ...

Tópico(s): Islamic Studies and History

2018 - Routledge | Quarterly Journal of Speech

Artigo Acesso aberto Revisado por pares

Yang Yu, Ning Li, Jiameng Qiu, Honghua Ge, Ximing Qin,

... the Abbreviations) complexes. In addition, a novel repressor, CHRONO, has been identified recently, but details of CHRONO’s function during repressing the circadian cycle remain unclear. Here we report that a domain of CHRONO mainly composed of α-helixes is critical to ... spectroscopy. This repression is fulfilled by interactions between CHRONO and a region on the C-terminus of ... defined in the Abbreviations) bind. Our resultsindicate that CHRONO and PER differentially function as BMAL1/CLOCK-dependent ...

Tópico(s): Plant Molecular Biology Research

2020 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences

Artigo Acesso aberto Revisado por pares

Zaheer Allam, Mark Nieuwenhuijsen, Didier Chabaud, Carlos Moreno,

... C The quarter-hour city: for a new chrono-urbanism.https://www.latribune.fr/regions/smart-cities/ ... ville-du-quart-d-heure-pour-un-nouveau-chrono-urbanisme-604358.htmlDate: Oct 5, 2016Date accessed: November ... 2016Google Scholar the concept advocates for so-called chrono-urbanism, supporting the notion that proximity-based planning ... urban restructuring, that aligns with the so-called chrono-urbanism concept, and via associated activities of local ... C The quarter-hour city: for a new chrono-urbanism.https://www.latribune.fr/regions/smart-cities/ ...

Tópico(s): Urban Transport and Accessibility

2022 - Elsevier BV | The Lancet Planetary Health

Revisão Acesso aberto Revisado por pares

Gerda K. Pot,

... timing of eating on health outcomes is called chrono-nutrition, and combines elements from nutritional research with chrono-biology. The objectives of this paper were to ... dietary patterns, introduce basic concepts and mechanisms of chrono-nutrition and discuss the evidence for the importance of sleep and chrono-nutrition in relation to health outcomes. Overall, chrono-nutrition could mediate the effects between sleep, diet ... research is needed to elucidate the importance of chrono-nutrition for metabolic health and its impact on ...

Tópico(s): Obesity, Physical Activity, Diet

2017 - Cambridge University Press | Proceedings of The Nutrition Society

Artigo Acesso aberto Revisado por pares

Radu Serban, Michael Taylor, Dan Negruţ, Alessandro Tasora,

Chrono::Vehicle is a module of the open-source multi-physics simulation package Chrono, aimed at modelling, simulation, and visualisation of wheeled ... assembling complex vehicle models, while leveraging the underlying Chrono modelling and simulation capabilities, allowing seamless interfacing to other optional Chrono modules (e.g., its granular dynamics and fluid- ... of a predefined subsystem template. Written in C++, Chrono::Vehicle is offered as a middleware library. In this paper, we provide an overview of the Chrono::Vehicle software design philosophy, its main capabilities and ...

Tópico(s): Model-Driven Software Engineering Techniques

2018 - | International Journal of Vehicle Performance

Artigo Acesso aberto Revisado por pares

Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland,

... that can confound the results. Here, we introduce Chronos, an algorithm for inferring gene knockout fitness effects ... proliferation dynamics after CRISPR gene knockout. We test Chronos on two pan-cancer CRISPR datasets and one longitudinal CRISPR screen. Chronos generally outperforms competitors in separation of controls and ... associations, particularly when longitudinal data is available. Additionally, Chronos exhibits the lowest copy number and screen quality bias of evaluated methods. Chronos is available at https://github.com/broadinstitute/chronos .

Tópico(s): Gene Regulatory Network Analysis

2021 - BioMed Central | Genome biology