Cid Ferreira Lopes, E. O. Cisalpino, R. J. Alvarenga, S Armond, Robson V. Pôrto, F. A. Maia, Yeddo Peixoto,
... Search for more papers by this authorE.O. Cisalpino, E.O. Cisalpino Belo Horizonte, razil Chief, II Clinica Dermatológica de ... Search for more papers by this authorE.O. Cisalpino, E.O. Cisalpino Belo Horizonte, razil Chief, II Clinica Dermatológica de ...
Tópico(s): Actinomycetales infections and treatment
1971 - Wiley | International Journal of Dermatology
Produção Nacional
Revisado por pares
Ludmila Matos Baltazar, Silvia Maria Cordeiro Werneck, Hellem Cristina Silva Carneiro, L.F. Gouveia, Thaiza Pereira de Paula, Ricardo Martins Duarte Byrro, Armando Silva‐Cunha, Betânia Maria Soares, Marcus Vinícius Lucas Ferreira, Danielle G. Souza, Marcos Pinotti, P.S. Cisalpino, Daniel Assis Santos,
... author on: Oxford Academic Google Scholar P.S. Cisalpino, P.S. Cisalpino Department of Microbiology Instituto de Ciências Biológicas Universidade ...
Tópico(s): Plant Pathogens and Fungal Diseases
2014 - Oxford University Press | British Journal of Dermatology
... June, 1964. Google Scholar 6 Furtado, T. A., Cisalpino, E. O., and Santos, U. M.: In vitro ...
Tópico(s): Research on Leishmaniasis Studies
1967 - Wiley | International Journal of Dermatology
Produção Nacional
Revisado por pares
Cid Ferreira Lopes, R. J. Alvarenga, E. O. Cisalpino, Maria Aparecida de Resende, Luiz Gonzaga de Oliveira,
Twenty-three patients with chromomycosis were treated with oral 5-fluorocytosine for periods ranging from 2 to 67 months. Sixteen were considered cured, after 3 consecutive monthly controls showing healing of the lesions and absence of fungi in mycologic and histopathologic examinations of biopsy specimens. Seven, in spite of initial clinical improvement, showed resistance to treatment. Associated treatment with amphotericin B, calciferol or thiabendazole failed to help patients resistant to 5-fluorocytosine. ...
Tópico(s): Antifungal resistance and susceptibility
1978 - Wiley | International Journal of Dermatology
Produção Nacional
Revisado por pares
Luiz Gonzaga de Oliveira, MARIA APARECIDA DE REZENDE, E. O. Cisalpino, YEDDO PEIXOTO DE FIGUEIREDO, Cid Ferreira Lopes,
In vitro 5-fluorocytosine sensitivity tests of strains were isolated from chromomycosis patients undergoing therapy. Tests were rountinely performed for 0.1, 1.0, 5.0 and 10.0 mug/ml 5-fluorocytosine concentrations. In two cases resistance could be demonstrated up to 60.0 and 100.0 mug/ml. Fungistatic activity of 5-fluorocytosine against the agents of chromomycosis was confirmed. Sensitivity tests are useful to detect resistance which may occur during treatment. They are also helpful for guiding ...
Tópico(s): Fungal Infections and Studies
1975 - Wiley | International Journal of Dermatology
Produção Nacional
Revisado por pares
Thaíssa de Oliveira Bastos, Betânia Maria Soares, Patrícia Silva Cisalpino, Isolda C. Mendes, Raquel Gouvêa dos Santos, Heloísa Beraldo,
A family of 2-pyridineformamide-derived thiosemicarbazones and their gallium(III) complexes were tested against several isolates of pathogenic Cryptococcus strains. On complexation the antifungal activity significantly increases, suggesting coordination to gallium(III) to be an interesting strategy of antifungal dose reduction.
Tópico(s): Antifungal resistance and susceptibility
2009 - Elsevier BV | Microbiological Research
Produção Nacional
Revisado por pares
D.M. Santos, Rodrigo M. Verly, Dorila Piló‐Veloso, Mário de María, Marcelo Addas‐Carvalho, Patrícia Silva Cisalpino, Betânia Maria Soares, Cláudio Galuppo Diniz, Luiz M. Farias, DP Moreira, Frédéric Frézard, Marcelo P. Bemquerer, Adriano M.C. Pimenta, Maria Elena de Lima,
LyeTx I, an antimicrobial peptide isolated from the venom of Lycosa erythrognatha, known as wolf spider, has been synthesised and its structural profile studied by using the CD and NMR techniques. LyeTx I has shown to be active against bacteria (Escherichia coli and Staphylococcus aureus) and fungi (Candida krusei and Cryptococcus neoformans) and able to alter the permeabilisation of l-α-phosphatidylcholine-liposomes (POPC) in a dose-dependent manner. In POPC containing cholesterol or ergosterol, permeabilisation ...
Tópico(s): Neurobiology and Insect Physiology Research
2009 - Springer Science+Business Media | Amino Acids
... s Le Diable amoureux by Annalisa Bottacin (Milan: Cisalpino-Goliardica, 1983), which details the most minor textual ...
Tópico(s): Historical and Literary Analyses
2002 - University of Toronto Press | Eighteenth-Century Fiction
Produção Nacional
Revisado por pares
Luciano dos Santos Feitosa, Patrícia Silva Cisalpino, Márcia Regina Machado dos Santos, Renato A. Mortara, Tânia Fraga Barros, Flávia Villaça Morais, Rosana Puccia, José Franco da Silveira, Zoilo Pires dè Camargo,
Tópico(s): Plant Disease Resistance and Genetics
2003 - Academic Press | Fungal Genetics and Biology
Produção Nacional
Revisado por pares
Luiz M. Farias, Antônio Helvécio Tótola, Cláudia Madeira Miranda, Marcelo Addas‐Carvalho, Carlos Américo Veiga Damasceno, C. A. P. Tavares, E. O. Cisalpino, Eliane Vieira,
A strain of Bacteroides fragilis, isolated from the marmoset Callithrix penicillata, produced protein(s) with bacteriocin activity (fragicilin). Two active fractions (36 and 150 kDa) were isolated by chromatography. The bacteriocin exhibited iso- and heteroantagonism. It remained stable between pH 3 and 10 and at 60 degrees C for 24 h. Pronase, trypsin, proteinase K and type VII protease inactivated the bacteriocin, giving evidence of its protein nature.
Tópico(s): Microbial Natural Products and Biosynthesis
1994 - Elsevier BV | Research in Microbiology
Produção Nacional
Revisado por pares
Flávio A. Amaral, Daniela Sachs, Vivian Vasconcelos Costa, Caio T. Fagundes, Daniel Cisalpino, Thiago M. Cunha, S. H. Ferreira, Fernando Q. Cunha, Tarcı́lia Aparecida Silva, Jacques R. Nicoli, Leda Quércia Vieira, Danielle G. Souza, Mauro Martins Teixeira,
The ability of an individual to sense pain is fundamental for its capacity to adapt to its environment and to avoid damage. The sensation of pain can be enhanced by acute or chronic inflammation. In the present study, we have investigated whether inflammatory pain, as measured by hypernociceptive responses, was modified in the absence of the microbiota. To this end, we evaluated mechanical nociceptive responses induced by a range of inflammatory stimuli in germ-free and conventional mice. Our experiments ...
Tópico(s): Acupuncture Treatment Research Studies
2008 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Produção Nacional
Revisado por pares
Betânia Maria Soares, Danielle L. da Silva, Gerdal Roberto de Sousa, José Cláudio Faria Amorim, Maria Aparecida de Resende, Marcos Pinotti, Patrícia Silva Cisalpino,
In this study, photodynamic inactivation (PDI) was used to inhibit in vitro growth and adhesion of different Candida isolates to buccal epithelial cells (BEC). Experimental conditions were optimized and 25 μM toluidine blue O (TBO) and 15 min of irradiation time by light emitting diode (LED) (energy density of 180 J/cm2) were selected due to higher reductions in cellular viability obtained after treatment. Reduction media of Log10 3.41 in viable cellular growth and media of 55% in the inhibition of adhesion ...
Tópico(s): Oral health in cancer treatment
2008 - Elsevier BV | Journal of Photochemistry and Photobiology B Biology
... Renaissance: Otto Brunfels Leonhart Fuchs Ulisse Aldrovandi Andrea Cisalpino Pierre Belon Konrad Gessner The Enlightenment: Nicolaus Steno ...
Tópico(s): Evolution and Science Education
2008 - Association of College and Research Libraries | Choice Reviews Online
Produção Nacional
Revisado por pares
Betânia Maria Soares, Daniel Assis Santos, Lidiane Meire Kohler, Giovana da Costa César, Inácio R. Carvalho, Marilena dos Anjos Martins, Patrícia Silva Cisalpino,
We report a clinical case of cerebral infection caused by Cryptococcus gattii in a 10 year-old boy. Clinical and laboratory exams did not demonstrate any apparent immunosuppressed state (HIV antibody and the tuberculin skin tests, both negative, were performed; blood cells count and immunoglobulin levels were within normality). Treatment was begun with amphotericin B-deoxycholate but renal toxicity signs led to its substitution by fluconazole. The infection proceeded even after treatment with fluconazole. ...
Tópico(s): Nail Diseases and Treatments
2008 - Elsevier BV | Revista Iberoamericana de Micología
Produção Nacional
Revisado por pares
Remo Castro Russo, Rodrigo Guabiraba, Cristiana C. Garcia, Lucíola S. Barcelos, Ester Roffê, Adriano L.S. Souza, Flávio A. Amaral, Daniel Cisalpino, Geovanni Dantas Cassali, Andrea Doni, Riccardo Bertini, Mauro Martins Teixeira,
Pulmonary fibrosis is characterized by chronic inflammation and excessive collagen deposition. Neutrophils are thought to be involved in the pathogenesis of lung fibrosis. We hypothesized that CXCR2-mediated neutrophil recruitment is essential for the cascade of events leading to bleomycin-induced pulmonary fibrosis. CXCL1/KC was detected as early as 6 hours after bleomycin instillation and returned to basal levels after Day 8. Neutrophils were detected in bronchoalveolar lavage and interstitium ...
Tópico(s): Pneumonia and Respiratory Infections
2008 - American Thoracic Society | American Journal of Respiratory Cell and Molecular Biology
Produção Nacional
Revisado por pares
Rosana Puccia, Juan G. McEwen, Patrícia Silva Cisalpino,
Paracoccidioides brasiliensis is a temperature-dependent dimorphic fungus and the agent of paracoccidioidomycosis (PCM), which is prevalent in rural workers of Latin American countries. Until a decade ago, most of the studies involving P. brasiliensis used clinical isolates, since environmental samples from soil are difficult to obtain. More recently, P. brasiliensis has been isolated from infected wild and domestic animals, especially from the nine-banded armadillo Dasypus novemcinctus in Brazil. ...
Tópico(s): Infectious Diseases and Mycology
2008 - Springer Science+Business Media | Mycopathologia
Produção Nacional
Revisado por pares
Fernanda Fraga Campos, Susana Johann, Betania Barros Cota, Tânia Maria de Almeida Alves, Luiz Henrique Rosa, Rachel Basques Caligiorne, Patrícia Silva Cisalpino, Carlos A. Rosa, Carlos Leomar Zani,
Paracoccidioidomycosis (PCM), a human mycosis caused by the dimorphic fungus Paracoccidioides brasiliensis, is a serious public health problem in several countries of Latin America. In our search we found that the crude extract of the endophytic fungus UFMGCB 551 was able to inhibit several clinical strains of P. brasiliensis, and was also active in the bioautographic assay against Cladosporium sphaerospermum. The endophytic fungus UFMGCB 551 was isolated from the plant Piptadenia adiantoides J.F. ...
Tópico(s): Fungal Infections and Studies
2010 - Wiley | Mycoses
Tiago Magalhães, Fernando Ribeiro, Ana Cisalpino Pinheiro, José Oliveira,
To evaluate the effects of a warm-up program on knee joint position sense in karatekas.Repeated measures design.Research laboratory.Ten young amateur karatekas (17.6 +/- 4.0 years of age).Knee joint position sense evaluated before and immediately after a warm-up program through active repositioning in open kinetic chain (OKC) and closed kinetic chain (CKC).At baseline testing no differences were observed between OKC and CKC in absolute (4.1 +/- 1.6 degrees vs. 3.4 +/- 2.0 degrees) and relative angular errors (2. ...
Tópico(s): Shoulder Injury and Treatment
2010 - Elsevier BV | Physical Therapy in Sport
Produção Nacional
Revisado por pares
Susana Johann, Patrícia Silva Cisalpino, Gisele Almeida Watanabe, Betânia Barros Cota, Ezequias Pessoa de Siqueira, Moacir Geraldo Pizzolatti, Carlos Leomar Zani, Maria Aparecida de Resende,
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis Almeida (Onygenales) that requires 1-2 years of treatment. In the absence of drug therapy, the disease is usually fatal, highlighting the need for the identification of safer, novel, and more effective antifungal compounds. With this need in mind, several plants employed in Brazilian traditional medicine were assayed on P. brasiliensis and murine macrophages. Extracts were prepared from 10 plant ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2010 - Taylor & Francis | Pharmaceutical Biology
Produção Nacional
Revisado por pares
Marjorie Mendes Marini, Tamiris Zanforlin, Patrícia Campi Santos, Roberto R. Moraes Barros, Anne CP Guerra, Rosana Puccia, Maria SS Felipe, Marcelo M. Brígido, Célia M.A. Soares, Jerônimo C. Ruiz, José Franco da Silveira, Patrícia Silva Cisalpino,
Abstract Background Paracoccidioides brasiliensis (Eukaryota, Fungi, Ascomycota) is a thermodimorphic fungus, the etiological agent of paracoccidioidomycosis, the most important systemic mycoses in Latin America. Three isolates corresponding to distinct phylogenetic lineages of the Paracoccidioides species complex had their genomes sequenced. In this study the identification and characterization of class II transposable elements in the genomes of these fungi was carried out. Results A genomic survey ...
Tópico(s): Plant Pathogens and Fungal Diseases
2010 - BioMed Central | BMC Genomics
Produção Nacional
Revisado por pares
Betânia Maria Soares, Orley Araújo Alves, Marcus Vinícius Lucas Ferreira, José Cláudio Faria Amorim, Gerdal Roberto de Sousa, Lívio de Barros Silveira, Renato Araújo Prates, Thiago Vinícius Ávila, Ludmila de Matos Baltazar, Danielle G. Souza, Daniel Assis Santos, Luzia V. Modolo, Patrícia Silva Cisalpino, Marcos Pinotti,
ABSTRACT Cryptococus gattii is an emergent primary human pathogen that causes meningismus, papilledema, high intracranial pressure and focal involvement of the central nervous system in immunocompetent hosts. Prolonged antifungal therapy is the conventional treatment, but it is highly toxic, selects for resistant strains, contributes to therapy failure and has a poor prognosis. Photodynamic inactivation (PDI) offers a promising possibility for the alternative treatment of cryptococcosis. The aim ...
Tópico(s): Nail Diseases and Treatments
2010 - Wiley | Photochemistry and Photobiology
Produção Nacional
Revisado por pares
Susana Johann, Nívea Pereira de Sá, Luciana Alves Rodrigues dos Santos Lima, Patrícia Silva Cisalpino, Betânia Barros Cota, Tânia MA Alves, Ezequias Pessoa de Siqueira, Carlos Leomar Zani,
The aim of this study was to isolate and identify the antifungal compounds from the extracts of Schinus terebinthifolius (Anacardiaceae) against clinical isolates of the pathogenic fungus Paracoccidioides brasiliensis. The hexane and dichlomethane fractions from leaves and stems of S. terebinthifolius were fractionated using several chromatography techniques to afford four compounds. The compounds isolated from S. terebinthifolius were identified as schinol (1), a new biphenyl compound, namely, 4'- ...
Tópico(s): Plant Pathogens and Fungal Diseases
2010 - BioMed Central | Annals of Clinical Microbiology and Antimicrobials
Produção Nacional
Revisado por pares
Daniel Assis Santos, Roberta Amália de Carvalho Araújo, Lidiane Meire Kohler, Jackson Machado‐Pinto, Júnia Soares Hamdan, Patrícia Silva Cisalpino,
Forty sequential isolates of Trichophyton rubrum were obtained from patients suffering from onychomycosis at two time points, before and after antifungal oral therapy. Strain differentiation by specific amplification of the two tandemly repeated elements (TRS-1 and TRS-2) of the ribosomal DNA of T. rubrum was performed. In addition, susceptibility tests were executed by the microdilution method with nine antifungal drugs: ketoconazole, itraconazole, fluconazole, miconazole, clotrimazole, isoconazole, ...
Tópico(s): Plant Pathogens and Fungal Diseases
2007 - Elsevier BV | International Journal of Antimicrobial Agents
Produção Nacional
Revisado por pares
Danielle G. Souza, Caio T. Fagundes, Flávio A. Amaral, Daniel Cisalpino, Lirlândia P. Sousa, Angélica T. Vieira, Vanessa Pinho, Jacques R. Nicoli, Leda Quércia Vieira, Iolanda M. Fierro, Mauro Martins Teixeira,
Abstract The appropriate development of an inflammatory response is central for the ability of a host to deal with any infectious insult. However, excessive, misplaced, or uncontrolled inflammation may lead to acute or chronic diseases. The microbiota plays an important role in the control of inflammatory responsiveness. In this study, we investigated the role of lipoxin A4 and annexin-1 for the IL-10-dependent inflammatory hyporesponsiveness observed in germfree mice. Administration of a 15-epi- ...
Tópico(s): Neonatal Respiratory Health Research
2007 - American Association of Immunologists | The Journal of Immunology
Produção Nacional
Revisado por pares
Ezequias Pessoa de Siqueira, Djalma Menezes de Oliveira, Susana Johann, Patrícia Silva Cisalpino, Betânia Barros Cota, Ana Rabello, Tânia Maria de Almeida Alves, Carlos Leomar Zani,
Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) ...
Tópico(s): Phytochemical compounds biological activities
2011 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
... Adriatica: saggi di storia economica e finanziaria, Bologna: Cisalpino. [Google Scholar], Ragusa (Dubrovnik) una Republica Adriatica. 46. ...
Tópico(s): Maritime Ports and Logistics
2011 - Taylor & Francis | Mediterranean Historical Review
Produção Nacional
Revisado por pares
Caio T. Fagundes, Vivian Vasconcelos Costa, Daniel Cisalpino, Flávio A. Amaral, Patricia R. Souza, Rafael Soares Correa de Souza, Bernhard Ryffel, Leda Quércia Vieira, Tarcı́lia Aparecida Silva, Alena Atrasheuskaya, G. M. Ignatyev, Lirlândia P. Sousa, Danielle G. Souza, Mauro Martins Teixeira,
Dengue is a mosquito-borne disease caused by one of four serotypes of Dengue virus (DENV-1-4). Severe dengue infection in humans is characterized by thrombocytopenia, increased vascular permeability, hemorrhage and shock. However, there is little information about host response to DENV infection. Here, mechanisms accounting for IFN-γ production and effector function during dengue disease were investigated in a murine model of DENV-2 infection. IFN-γ expression was greatly increased after infection ...
Tópico(s): Viral Infections and Vectors
2011 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Luciana de Carvalho Tavares, Susana Johann, Tânia Maria de Almeida Alves, J.C. Guerra, Elaine M. Souza–Fagundes, Patrícia Silva Cisalpino, Adaı́lton J. Bortoluzzi, Giovanni F. Caramori, Rafael de Mattos Piccoli, Hugo T. S. Braibante, Mara E. F. Braibante, Moacir Geraldo Pizzolatti,
A series of new 6-quinolinyl and quinolinyl N-oxide chalcones were efficiently prepared. All chalcones were tested by minimal inhibitory concentration (MIC) against three species of Candida, Cryptococcus gattii and Paracoccidioides brasiliensis. The effect of these compounds was also tested on the survival and growth of the human cancer cell lines UACC-62 (melanoma), MCF-7 (breast), TK-10 (renal) and leukemic cells, Jurkat and HL60. The compounds tested presented strong activity against P. brasiliensis, ...
Tópico(s): Fungal Plant Pathogen Control
2011 - Elsevier BV | European Journal of Medicinal Chemistry
Produção Nacional
Revisado por pares
Luciana Alves Rodrigues dos Santos Lima, Susana Johann, Patrícia Silva Cisalpino, Lúcia Pinheiro Santos Pimenta, Maria Amélia D. Boaventura,
INTRODUCTION: Fatty acids are abundant in vegetable oils. They are known to have antibacterial and antifungal properties. METHODS: Antifungal susceptibility was evaluated by broth microdilution assay following CLSI (formerly the NCCLS) guidelines against 16 fungal strains of clinical interest. RESULTS: In this work, fatty acid methyl esters (FAME) was able to inhibit 12 clinical strains of the pathogenic fungus Paracoccidioides brasiliensis and were also active in the bioautographic assay against ...
Tópico(s): Cocoa and Sweet Potato Agronomy
2011 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Mila Fernandes Moreira Madeira, Celso Martins Queiroz‐Junior, Graciela Mitre Costa, Patrícia Campi Santos, Elcia Maria Varize Silveira, Gustavo Pompermaier Garlet, Patrícia Silva Cisalpino, Mauro Martins Teixeira, Tarcı́lia Aparecida Silva, Danielle G. Souza,
Periodontal disease (PD) is a chronic inflammatory and alveolar bone destructive disease triggered by microorganisms from the oral biofilm. Oral inoculation of mice with the periodontopathogen Aggregatibacter actinomycetemcomitans (Aa) induces marked alveolar bone loss and local production of inflammatory mediators, including Macrophage Migration Inhibitory Factor (MIF). The role of MIF for alveolar bone resorption during PD is not known. In the present study, experimental PD was induced in BALB/c ...
Tópico(s): Macrophage Migration Inhibitory Factor
2011 - Elsevier BV | Microbes and Infection