Waldemar Januszczak, Tim Tezisler, Ivan Armstrong, Robin Garson, Steve Lawless, John Dugdale, Cathy Hill, Barbara Hall, Nigel Botherway, Marquess, Andrew Warshaw, Keith Butterfield, Jim Munro, Sean O'Brien, Mr S S, Dr J Booth, Dan Pearson, John Peter, L R, Pam Barrett, Emma Moore, Amanda Ursell, Keir Knight, Chris Tarrant, John Jay, Susan d'Arcy, Dorothy Woodcock, Michael Kelly, Frank Whitford, Ivo Tennant, Stephen Pettit, Stewant Lee, Alistair Scott, David Smith, Kirstie Hamilton City Editor, Elizabeth McKee, Melanie Phillips, Nick Pitt, Neil Wormald, Reiner Gatermann, Helen Vaughan, Andrew Sullivan, Clive Davis, Wynne Godley, Stephen Grey, Mary Wilson, Dylan Jones, Ruth Inglis, Bob Mee, Edward Platt, Simon Read, Shelley von Struncked, Tony Allen-Mills, Simon Wilde, D C, Robert Sandall, Martin James, Eleanor Mills, Anthony Sattin, Alison Brace, Robert Winnett, Margaret Walters, Irwin Stelzer, Phillip Williams, Andrew Wild, Peter Wilson, Roger Anderson, David Dougill, Denise Fleig, Sarah Toyne, David Hewson, Samuel Menashe, Louis Lince, Tom Hastie, Chris Hastings, Deborah Savidge, Margaret Coles, Harvey Porlock, Margarette Driscoll, Hugh Canning, Tania Alexander, David Caims, Jeremy Clarkson, Stewart Lee, David Gill, Edward Porter, Louise Taylor, Peter Blake, Mr D Allen, David Coleman, Mark Barrow, Robert Harris, Nick Newman's, Stephen Jay Gould Author and Professor, Peter Whiteside, Liz Jones, Graham Otway, John O'Leary, Peter White, Nick Gardner, Derek Donning, Paul Ham, J Biggane, Stuart Wavell, René Jacobs, Josephine Smit, Paul Donovan, Ted Landsler, Nicholas Meew, Paul Routledge, Piers Paul Read, Sue Lawrence, Hugo Wickers, Justin Cartwright, Stepehn Jones, Brian Farrelly, Derek Clements, Roger Scruton, Garth Pearce, Paul Driver, Adam Novak, Nicholas Hellen, Maeve Sheehan, John Follain, Kate d'Anch Smith, Ian Hawkey, Paul Buysse's, Sue Fox, David Leppard, John Eggleston, M M, Alicia Wyllie, Dave Hannigan, Mark Edwards, Steve Farrar Science Correspondent, Kirstie Hamilton, Tom Shone, Sarah Gracie, Susan Clark, David Lawrenson, Nicholas Rufford Home Affairs Editor, R S, Phil Baker, W Harbert, Robert Lacey, Michael Winner, Hugo Barnacle, Edward Porler, Karen Bayne, Michael Watkins, John Mackay, Anna Pavord, Sue Reid, Raymond Keene, Elizabeth Reed Smith, Ian Phillips, Uki Goni, Andrew Roberts, Marie Colvin, John Rocha, Diana Wright, William Peakin, Jim Smith, Ed Cairns Policy Adviser, Suan Vaugham Hamblen, Helen Hawkins, Stephen Jones, Paul Nuki Consumer Affairs Editor, W P Graham, Richard Evans, Uzi Mahnaimi, Nick Cain, S Richardson, Natalie Graham, Dr William Thomson, Andrew Smith, Tony Allen Mills, M J, Martin Searby, Keith Wheatley, Claire Oldfield, Rosie Thomas, David Walsh, Ryan Sullivan, Lols Rogers Medical Correspondent, Jack Grimston, Vanessa Channer, Karen Armstrong, Bryan Appleyard, Stephen Armstrong, Seamus Heaney, Sally O Reilly, Dispesh Gadher, Paul Kavanagh, Josh Salzmann, Mark Prigg, Colin Cowdrey, Richard Woods, Roland White, Garth Alexander, Catherine Digy-Rogers, Saint Tony, Ronald Bower, A Wrightman, Maurice Chittenden, Alex Fortune, Andrew Lorenz Business Editor, Judith O'Reilly, Mark Franchetti, Jonathan Powell, Ray Hutton, John Zwolinski, Peter Watts, Jon Ungoed Thomas, Tara Palmer-Tomkinson, Margaret Cook, Michael Sheridan, Peter Stringfellow, Chris Dignam, Harry Armitage, Sean Hargrave, John Harlow, Christine Webb, Matthew Lynn, Godfrey Smith, Michael Austin, Graham Thorner, Bob Davis, Michael Hodges, John Waples, R Adlem, Jeremy Hart, Juliet Terzieff, A A Gill, Matthew Campbell, Brian Glanville, David James, Antonia Fraser, Bill Martin, David Hutcheon, J F, Christine Swann, Robert Johnston, Paul Hooper, Cherry Norton, M B, Andrew Lorenz, Naomi Caine, Adrian Levy, David Wickers, Jane Hardy, Roger Dobson, Tom Rhodes, Hugh Maloney, Damian Thompson, E S, Paul Brennan, Andrew Frankel, Nicholas Hellen Media Correspondent, Joe Lovejoy, Hilary Hinchliffe, Jonathan Futrell, Rupert Steiner, Cathy Scott Clark, Dan Cairns, Zone Linkson, David Parsley, David Smith Economics Editor, Penny Perrick, Soraya Khashoggi, Anthony Howard, Philip Kingsley The leading trichologist, Sarah Baxter, Ken Silverstein, Carey Scott, Walter Ellis, Stephen Boyd, Meg Mathews, Joanna Simon, India Knight, Chris Feetenby, Simon Howard, Danny Danziger, Barry Newcombe, Martyn Lambert, Dominic Rushe, Boris Schapiro, Karen Robinson,
... Fashion Diary Frock Horror Who's that Girl? Claire Forlani, who stars opposite Brad Pitt in his new ...
1999 - Gale Group | Sunday Times HA GDA
Sylvie Forlani, Claire Bonnerot, Suzanne Capgras, Jean–François Nicolas,
ABSTRACT In the mouse, transcriptional permissiveness is established in the fertilized egg prior to the activation of zygotic genes at the 2-cell stage. Therefore, gene inactivity initiated at the end of gametogenesis results from a complex process, involving more than an inhibition of the basal transcriptional apparatus. We have examined the ability of the first intron (I1) of the human hypoxanthine phosphoribosyl transferase gene, which functions as an enhancer in embryonic stem cells, to activate ...
Tópico(s): Reproductive Biology and Fertility
1998 - The Company of Biologists | Development
Clémence Fournier, Mathieu Barbier, Agnès Camuzat, Vincent Anquetil, Serena Lattante, Fabienne Clot, Cécile Cazeneuve, Daisy Rinaldi, Philippe Couratier, Vincent Deramecourt, Mario Sabatelli, Serge Belliard, Martine Vercelletto, Sylvie Forlani, Ludmila Jornéa, Eric Leguern, Alexis Brice, Isabelle Le Ber, Alexis Brice, Sophie Auriacombe, Serge Belliard, Frédéric Blanc, Claire Bouteleau-Bretonnière, Mathieu Ceccaldi, Philippe Couratier, Mira Didic, Bruno Dubois, Charles Duyckaerts, Frédérique Etcharry-Bouix, Véronique Golfier, Didier Hannequin, Lucette Lacomblez, Isabelle Le Ber, Richard Lévy, Bernard‐François Michel, Florence Pasquier, Catherine Thomas-Antérion, Jérémie Pariente, François Sellal, Martine Vercelletto, Eve Benchetrit, Hugo Bertin, Anne Bertrand, Anne Bissery, Stéphanie Bombois, Marie-Paule Boncœur, Pascaline Cassagnaud, Mathieu Chastan, Yaohua Chen, Marie Chupin, Olivier Colliot, Philippe Couratier, Xavier Delbeucq, Vincent Deramecourt, Christine Delmaire, Emmanuel Gerardin, Claude Hossein-Foucher, Bruno Dubois, Marie‐Odile Habert, Didier Hannequin, Géraldine Lautrette, Thibaud Lebouvier, Isabelle Le Ber, Stéphane Lehéricy, Benjamin Le Toullec, Richard Lévy, Kelly Martineau, Marie‐Anne Mackowiak, Jacques Monteil, Florence Pasquier, G. Petyt, Pierre-François Pradat, Assi-Hervé Oya, Daisy Rinaldi, Adeline Rollin‐Sillaire, François Salachas, Sabrina Sayah, David Wallon,
A (GGGGCC)n repeat expansion in C9orf72 gene is the major cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). The relations between the repeats size and the age at disease onset (AO) or the clinical phenotype (FTD vs. ALS) were investigated in 125 FTD, ALS, and presymptomatic carriers. Positive correlations were found between repeats number and the AO (p < 10e-4) but our results suggested that the association was mainly driven by age at collection (p < 10e-4). A weaker association ...
Tópico(s): Prion Diseases and Protein Misfolding
2018 - Elsevier BV | Neurobiology of Aging
C. Pinna, Tommaso Laurenzi, Fabio Forlani, Luca Palazzolo, Claire Beatrice Nolan, Michael S. Christodoulou, P. Cortesi, Andrea Pinto, Ivano Eberini, Andrea Kunova, Sabrina Dallavalle,
The fulfilment of the European “Farm to Fork” strategy requires a drastic reduction in the use of “at risk” synthetic pesticides; this exposes vulnerable agricultural sectors—among which is the European risiculture—to the lack of efficient means for the management of devastating diseases, thus endangering food security. Therefore, novel scaffolds need to be identified for the synthesis of new and more environmentally friendly fungicides. In the present work, we employed our previously developed 3D ...
Tópico(s): Phytochemical compounds biological activities
2023 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Marie Coutelier, Monia Hammer, Giovanni Stévanin, Marie‐Lorraine Monin, Claire-Sophie Davoine, Fanny Mochel, Pierre Labauge, Claire Ewenczyk, Jinhui Ding, J. Raphael Gibbs, Didier Hannequin, Judith Melki, Annick Toutain, Vincent Laugel, Sylvie Forlani, Perrine Charles, Emmanuel Broussolle, Stéphane Thobois, Alexandra Afenjar, Mathieu Anheim, Patrick Calvas, Giovanni Castelnovo, T. de Broucker, Marie Vidailhet, Antoine Moulignier, Robert T. Ghnassia, Chantal Tallaksen, Cyril Mignot, Cyril Goizet, Isabelle Le Ber, Elisabeth Ollagnon‐Roman, Jean Pouget, Alexis Brice, Andrew Singleton, Alexandra Dürr,
Importance Molecular diagnosis is difficult to achieve in disease groups with a highly heterogeneous genetic background, such as cerebellar ataxia (CA). In many patients, candidate gene sequencing or focused resequencing arrays do not allow investigators to reach a genetic conclusion. Objectives To assess the efficacy of exome-targeted capture sequencing to detect mutations in genes broadly linked to CA in a large cohort of undiagnosed patients and to investigate their prevalence. Design, Setting, and Participants ...
Tópico(s): Mitochondrial Function and Pathology
2018 - American Medical Association | JAMA Neurology
Jean‐Loup Méreaux, Claire-Sophie Davoine, David Pellerin, Giulia Coarelli, Marie Coutelier, Claire Ewenczyk, Marie‐Lorraine Monin, Mathieu Anheim, Isabelle Le Ber, Stéphane Thobois, Florent Gobert, Léna Guillot‐Noël, Sylvie Forlani, Ludmila Jornéa, Anna Heinzmann, Aude Sangaré, Bertrand Gaymard, Lucie Guyant‐Maréchal, Perrine Charles, Cécilia Marelli, Jérôme Honnorat, Bertrand Degos, François Tison, Sophie Sangla, M. Simonetta‐Moreau, François Salachas, Maya Tchikviladzé, Giovanni Castelnovo, Fanny Mochel, Stephan Klebe, Anna Castrioto, Silvia Fenu, Aurélie Méneret, Frédéric Bourdain, Marion Wandzel, Virginie Roth, Céline Bonnet, Florence Riant, Giovanni Stévanin, Sandrine Noël, Anne‐Laure Fauret‐Amsellem, Melanie Bahlo, Paul J. Lockhart, Bernard Brais, Mathilde Renaud, Alexis Brice, Alexandra Dürr,
SCA27B caused by FGF14 intronic heterozygous GAA expansions with at least 250 repeats accounts for 10-60% of cases with unresolved cerebellar ataxia. We aimed to assess the size and frequency of FGF14 expanded alleles in individuals with cerebellar ataxia as compared with controls and to characterize genetic and clinical variability.
Tópico(s): Nuclear Structure and Function
2023 - Elsevier BV | EBioMedicine
Leila Sellami, Benoît Rucheton, Imen Ben Younes, Agnès Camuzat, Dario Saracino, Daisy Rinaldi, Stéphane Epelbaum, Carole Azuar, Richard Lévy, Sophie Auriacombe, Didier Hannequin, Jérémie Pariente, Mathieu Barbier, Claire Boutoleau‐Bretonnière, Philippe Couratier, Florence Pasquier, Vincent Deramecourt, Mathilde Sauvée, Marie Sarazin, Julien Lagarde, Carole Roué-Jagot, Sylvie Forlani, Ludmila Jornéa, I. Rodenhiser David, Eric LeGuern, Bruno Dubois, Alexis Brice, Fabienne Clot, Foudil Lamari, Isabelle Le Ber,
GRN mutations are frequent causes of familial frontotemporal degeneration. Although there is no clear consensual threshold, plasma progranulin levels represent an efficient biomarker for predicting GRN mutations when decreased. We evaluated plasma levels to determine whether it could also predict age at onset, clinical phenotype, or disease progression in 160 GRN carriers. Importantly, progranulin levels were influenced by gender, with lower levels in male than in female patients in our study. Although ...
Tópico(s): Neurological diseases and metabolism
2020 - Elsevier BV | Neurobiology of Aging
Dario Saracino, Karim Dorgham, Agnès Camuzat, Daisy Rinaldi, Armelle Rametti‐Lacroux, Marion Houot, Fabienne Clot, Philippe Martin-Hardy, Ludmila Jornéa, Carole Azuar, Raffaella Migliaccio, Florence Pasquier, Philippe Couratier, Sophie Auriacombe, Mathilde Sauvée, Claire Boutoleau‐Bretonnière, Jérémie Pariente, Mira Didic, Didier Hannequin, David Wallon, Olivier Colliot, Bruno Dubois, Alexis Brice, Richard Lévy, Sylvie Forlani, Isabelle Le Ber,
Objective Neurofilament light chain (NfL) is a promising biomarker in genetic frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). We evaluated plasma neurofilament light chain (pNfL) levels in controls, and their longitudinal trajectories in C9orf72 and GRN cohorts from presymptomatic to clinical stages. Methods We analysed pNfL using Single Molecule Array (SiMoA) in 668 samples (352 baseline and 316 follow-up) of C9orf72 and GRN patients, presymptomatic carriers (PS) and controls aged ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2021 - BMJ | Journal of Neurology Neurosurgery & Psychiatry
I Dajti, José Ignacio Valenzuela, L Boccalatte, Nicolas A Gemelli, Dantwan Smith, Nagendra N. Dudi‐Venkata, Hidde M. Kroon, Tarik Sammour, Matthew M. Roberts, D Mitchell, K Lah, A Pearce, Dion Morton, Amanda Dawson, A Drane, Claire Sharpin, Ramesh Nataraja, Maurizio Pacilli, Daniel Cox, Vijayaragavan Muralidharan, Georgina Riddiough, Edmund Clarke, Wael Jamel, Kirby R. Qin, Peter Pockney, Daron Cope, N Egoroff, Natalie Lott, Sven Putnis, S De Robles, Zen Yang Ang, Martin Mitteregger, Stefan Uranitsch, Marjorie Stiegler, Gerald Seitinger, Felix Aigner, D B Lumenta, Sebastian P. Nischwitz, Erika Richtig, Mauro Pau, Petra Srekl-Filzmaier, Nicolas Eibinger, Birgit Michelitsch, Melanie Fediuk, A Papinutti, Geoffrey Seidel, Joseph Kahn, Tina Cohnert, Donna A. Messner, F. Ofner, J Presl, Márta Varga, Michael Weitzendorfer, K. Emmanuel, Alf-Dorian Binder, Marc Zimmermann, S Holawe, Emeka Nkenke, Christoph Grimm, M Kranawetter, Ashrarur Rahman Mitul, Nazmul Islam, Syed S. Karim, Niels Komen, Sven Putnis, S De Robles, Emily Ang, Herbert De Praetere, Tim Tollens, G Schols, C. Smets, Laura Haenen, Jorien Quintens, K Van Belle, Gabriëlle H. van Ramshorst, Piet Pattyn, Liesbeth Desender, Thomas Martens, Dirk Van de Putte, Philip Lerut, Aude Grimonprez, Marcus L.F. Janssen, G. De Smul, P. Wallaert, Jef Van den Eynde, Wouter Oosterlinck, Raf Van den Eynde, An Sermon, A. Boeckxstaens, Anne-Laure Cordonnier, Jeroen De Coster, Joris Jaekers, Constantinus Politis, Marc Miserez, Nicolas Duchateau, Charles de Gheldere, Nicolas Flamey, Piet Pattyn, A Christiano, Benedetta Guidi, A L Minussi, Sílvia Castro, Willy Okoba, F H R Maldonado, Paulo Oliveira, Tiago Antônio Baldasso, Luciano Marques dos Santos, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Laércio Pol Fachin, Tainá Santos Bezerra, Aldo Vieira Barros, A Silva, A L S Leite, Daniela Silvestre, C Carvalho Ferro, M S Araujo, L. M. Lopes, P D Damasceno, D H S Araujo, Gustavo Andreazza Laporte, M Salem, Marco Guimarães-Filho, Lucas Souto Nacif, Ronald Luiz Gomes Flumignan, Luís CU Nakano, Danielle Akemi Bergara Kuramoto, A L S Aidar, Mariana Raffo Pereda, R M Correia, Brena Costa Santos, Alzira Alves de Siqueira Carvalho, Jorge Eduardo de Amorim, Henrique Jorge Guedes Neto, Libnah Leal Areias, Álvaro Francisco Lopes de Sousa, Carolina Dutra Queiroz Flumignan, W G Lustre, Doris Hupfeld Moreno, Nathana Prado de Almeida Barros, José Carlos Costa Baptista‐Silva, Leandro Luongo de Matos, L P Kowaski, Marco Aurélio Vamondes Kulcsar, KS Nunes, Marcos F.S. Teixeira, Rafael Leite Nunes, Takeshi Ijichi, N. J. Kim, Ana Beatriz Pontes Marreiro, Bárbara Müller, Joseph Awada, Glauco Baiocchi, Luiz Paulo Kowalski, JG Vartanian, Fabiana B. Makdissi, Samuel Aguiar, Nuno Marques, Genival Barbosa de Carvalho, Tatiana Marques, Emne Ali Abdallah, Charles Edouard Zurstrassen, Jamie Gross, Stênio de Cássio Zéqui, Bruna Tirapelli Gonçalves, Sigrid de Sousa dos Santos, João Pedreira Duprat Neto, Felipe José Fernández Coimbra, Rafael De Cicco, Flávio Roberto Takeda, Ivan Cecconello, Ulysses Ribeiro, A Gatti, R Oliva, C Nardi, Mihail Slavchev, Boyko Atanasov, Nikolay Belev, Angela Dell, David L. Bigam, Khaled Dajani, S Al Riyami, Janet Martin, Davy Cheng, Hua Yang, A Fayad, François Martin Carrier, E. Amzallag, Joannie Desroches, Marie T. Ruel, Natasha Caminsky, Marylise Boutros, J Moon, E. G. C. Wong, Tsafrir Vanounou, Jonathan Pelletier, S Wong, Elie Girsowicz, J Bayne, Daniel I. Obrand, Heather L. Gill, Oren K. Steinmetz, Kenneth MacKenzie, Marie‐Amélie Lukaszewski, Ghader Jamjoum, Philippe Richebé, Olivier Verdonck, S Discepola, Nathalie Godin, M. Idrissi, Vincent Lecluyse, Geneviève Côté, Sebastian Demyttenaere, Richard Garfinkle, Marylise Boutros, A Kouyoumdjian, Marylise Boutros, Sinziana Dumitra, J Moon, E. G. C. Wong, Kosar Khwaja, Lan Luo, Marie‐Amélie Lukaszewski, Heather L. Gill, Gerald J. Berry, Adrienne Liberman, Elie Girsowicz, J Bayne, Daniel I. Obrand, Oren K. Steinmetz, Kenneth MacKenzie, Severin Schmid, Jonathan Spicer, Mehdi Farsi, Jad Abou‐Khalil, Étienne J. Couture, Seyede Momeneh Mohammadi, Hugo Tremblay, Nathalie Gagné, Anne Bergeron, Alexis F. Turgeon, O. Costerousse, David Bellemare, C. Babin, Catherine Blier, M L Wood, Amit Persad, Gary Groot, Hau Pham, Frédérick D’Aragon, Élaine Carbonneau, Maude Bouchard, Marie-Hélène Masse, F Pesant, Jennifer Héroux, Paul J. Karanicolas, Julie Hallet, A Nadler, Avery B. Nathens, M Ko, A Brar, Kelly Mayson, B Kidane, Sadeesh Srinathan, M Escudero, Janette T. Reyes, María Marta Modolo, P Ramirez Nieto, Rodrígo Sepúlveda, A Bolbarán, Andrés Molero‐Chamizo, Isaac Ruiz, Gabriel Reyes, Rafael Salas, Cristóbal Suazo, Rodrigo Muñoz, E Grasset, Martín Inzunza, Nicolás Besser, M J Irarrázaval, Cristián Jarry, Felipe Bellolio, C A Romero Manqui, M Ruiz Esquide, T. Fuentes, José Luis Campos, C. Perez, Payton Cabrera, Raúl Eduardo Pinilla Morales, Óscar Guevara, LJ Jimenez Ramirez, B G Velasquez Cuasquen, Damián Mora, A Bonilla, Sandra Diaz, E Manrique,
To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide ...
Oxford University Press
Dmitri Nepogodiev, Aneel Bhangu, James Glasbey, Elizabeth Li, Omar Omar, Joana F F Simoes, Tom Abbott, Osaid Alser, Alexis Arnaud, Brittany Bankhead-Kendall, Kerry Breen, Miguel F Cunha, Giana H. Davidson, Salomone Di Saverio, Gaetano Gallo, Ewen A. Griffiths, Rohan R Gujjuri, Peter Hutchinson, Haytham M.A. Kaafarani, Hans Lederhuber, Markus Löffler, Hassan Mashbari, Ana Minaya‐Bravo, Dion Morton, David Moszkowicz, Francesco Pata, George Tsoulfas, Mary L Venn, Daniel Cox, April Camilla Roslani, Felix Alakaloko, J.P. de Vries, Mahmoud Al Aaraj, Tom Abbott, Tom Abbott, Mutwakil OM Abdalla, Ahmed Samir Abdelaal, Adesoji Ademuyiwa, Thomas Aherne, Osman Ali, Ghadah Z Alkadeeki, Ana C. Almeida, Mahmoud Maher Abdelnaby Alrahawy, Graeme K. Ambler, Ehab Alameer, Stefano Andreani, Beatriz De Andrés-Asenjo, L López Antoñanzas, Salah G. Aoun, F Ashoush, Knut Magne Augestad, R Avellana, Funbi Ayeni, J Ayorinde, B H Babu, M. Baig, O Bajomo, Omer Baker, Markus Baker, Alexander J. Baldwin, Vin Shen Ban, Ryan Baron, Alberto G. Barranquero, Conor Barry, A Di bartolomeo, Gary Alan Bass, Michael Bath, H. Hunt Batjer, Andrew J. Beamish, Ajay Belgaumkar, Matthew N Bence, Ruth Benson, Juan Carlos Bernal-Sprekelsen, Anuradha R. Bhama, Avi Bhavaraju, Walter L. Biffl, Chris Blundell, Alex Boddy, Alexander B.J. Borgstein, David C. Bosanquet, Karen Bosch, Ahmad Bouhuwaish, Mehmet Abdussamet Bozkurt, Collin EM Brathwaite, Benjamin Brown, Oliver Brown, A Brown, Igor Lima Buarque, A.D. Bueno Cañones, Mustafa R Bulugma, Josh Burke, Matthew H V Byrne, Elima P Cagigal-Ortega, Rachael A. Callcut, Francesca Di Candido, M Canova, William Carlos, Edward Caruana, Liam D. Cato, Andrew B Catton, Andrea Pisani Ceretti, T Chase, Francesco Chiara, Abeed H. Chowdhury, Eric A Chung, Pierfranco Maria Cicerchia, Ethan C.S. Clough, Natasha Coleman, Chris Collins, Michelle Collins, Emily Colonna, Lara Valentina Comini, Patrick A. Coughlin, Laura Fernández-Gomez Cruzado, Brian R Davidson, Richard Davies, Emma Jane Davies, Niall F. Davis, Brett E Dawson, Benjamin Dean, Maria Garcia-Conde Delgado, José J. Diaz, Kathryn E Dickson, Manuel Díez‐Alonso, Ján Dixon, Matthew Doe, Thomas D Drake, Frederick Thurston Drake, John P. Duffy, Declan F.J. Dunne, Naomi JM Dunne, Virginia María Durán-Muñoz-Cruzado, Alexander Durst, N Eardley, John Edwards, Ahmed Hossam Elfallal, Mahmoud Elfiky, Jessie A. Elliott, Sameh Hany Emile, K Emslie, Frederick W Endorf, Jamie L. Engel, Diego Tristán Enjuto Martínez, Eric Etchill, Jonathan P Evans, Brian A Fahey, Carlos Faria, Carlo V. Feo, Henry J.M. Ferguson, Beatriz Dieguez Fernandez, Andres Garcia Fernandez, Antonio J Fernández, Borja Camacho Fernández-Pacheco, J.E.F. Fitzgerald, Giovanni Battista Fonsi, Roser Font, Amy Fowler, Kenneth R. Fretwell, Lorena Sanchon Fructuoso, Giuseppe Fusai, M Hernández-García, Miguel Ángel García Ureña, C Gill, Suzanne S. Gisbertz, Roberto Del Giudice, Maria Carmela Giuffrida, Matteo Di Giuseppe, María Fanjul Gómez, Ewen A. Griffiths, C A Guariglia, Alison Hainsworth, Bria J. Hall, James RW Hall, John Hammond, Maha H. Haqqani, Ewen M. Harrison, Joshua P. Hazelton, Maarten van Heinsbergen, Arnold D. Hill, Caroline Hing, Sameer Hirji, Michael Ho, Charlotte Holbrook, Thomas Holme, James Hopkins, David Hopkinson, Fahad Hossain, Victoria Hudson, Jane L Hughes, Eui-Hyoung Hwang, Mohamed Ibrahim, S M Isolani, Michael D. Jenkinson, Hillary E. Jenny, Deva S. Jeyaretna, Robert Jones, Andy Jones, Pascal Jonker, Maria L Jönsson, Doireann Joyce, Kyle J. Kalkwarf, Sivesh K. Kamarajah, Mohamed El‐Kassas, Dara O. Kavanagh, James M Keatley, Mohamed A Khalefa, Jim Khan, Bilal H. Kirmani, A Kisiel, S. Kouris, Mikolaj Kowal, Peter Labib, John O. Larkin, Johannes C. Lauscher, Wouter K. G. Leclercq, Frances SJ Ledesma, André M. Leite-Moreira, Elaine Leung, Sophia E Lewis, Maria João Lima, Daniel J. Lin, Helen H. Liu, Aoïfe Lowery, Saida Martel Lozano, C Luney, Mariana Magalhães Maia, Nicolò Maria Mariani, Marco V. Marino, Angelo Alessandro Marra, Christopher L. Marsh, Robert C.G. Martin, Simon McCluney, Robert C. McIntyre, S McKay, Kevin McKevitt, Ashley D. Meagher, Mohammad Q Mehdi, Brian Mehigan, Melania Gonzalez-De Miguel, Maria-Carmen De Miguel-Ardevines, Sarah Mills, Helen Mohan, John Moir, John RT Monson, Joana M Monteiro, Maria Teresa Montella, C Soto Montesinos, Marwa Morgom, Francisco Serra E Moura, J.M. Mugüerza, Suzanne Murphy, Paola De Nardi, David N Naumann, Paul Neary, David TA Neely, Joshua S Ng-Kamstra, Albert WT Ngu, Truong An Nguyen, G E Nita, Quentin Nunes, Rachel M. Nygaard, Lindsay O’Meara, John O’Neill, Barbara U. Okafor, Steven A. Olson, Aung Oo, Pablo Collera Ormazabal, Alexander Osorio, Max Pachl, James T Parry, Panna Patel, Luis Eduardo Pérez‐Sánchez, Ana Nogués Pevidal, A P Pezzuto, Matthew M. Philp, Thomas Pinkney, Joerg M. Pollok, Meical Povey, Alfredo Alonso Poza, Amarkumar Dhirajlal Rajgor, Jagan Rao, Dimitri Aristotle Raptis, Henry E. Rice, Paul F. Ridgway, Ana Munoz Rivas, Juan Carlos Rodríguez-Sanjuán, Luke Rogers, Anna Da Roit, Rebecca Rollett, José L. Romera, Siobhán Rooney, V Roxo, Bertrand Le Roy, Eduardo E Rubio, Carolina Castro Ruiz, Manuel Losada Ruiz,
Summary Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within ...
Elsevier BV
Timothy Fairbairn, Ian Kemp, Andrea S. Young, Christina Ronayne, Janet Barton, J. Crawford Crowe, L. McQuade, Nichola Clarkson, Michail Sionas, Angela Tobin, Sarah Feeney, Deborah E. Dickerson, Jacqueline Currie, Robert D. Shaw, C. Sudarshan, Yasir Abu-Omar, Michael O’Sullivan, William R. Davies, Rebecca McClean, Lisa Wong, Göher Ayman, Bushra S. Rana, Lynne Williams, Rosemary A. Rusk, Rajesh Kharbanda, George Krasopoulos, Jim Newton, Stephanie Lloyd, Deborah Barker, H. L. Naylor, Stuart W Grant, Anu Mary Oommen, Thabitha Charles, Sarah Mackie, Martin Sherwood, Elaine Pickett, James Cockburn, Adam de Belder, Amit Modi, Jessica Parker, Nicola Skipper, Sara Appasamy, Cath Thomson, Ari Gomes, Neil Moat, Cesare Quarto, Rashmi Yadav, Shufang Wang, Teijo Palovaara, Suad Warsama, John Rawlins, Alison Calver, Geoff Tsang, Miskolczi Szabolcs, Karen Banks, Zoe Nicholas, Sam Gough, Julie Bigg, Judith Radmore, Dhrubo Rakhit, Benoy N. Shah, Di Gardner, Daniel J. Blackman, Michael S. Cunnington, Betsy Evans, Francesco Pirone, Kalyana Javangula, Kathryn Somers, Helen L. Reed, N. Gregory, Dominik Schlosshan, Katrina Bounford, Paul D. Williams, Andrew Goodwin, Sharareh Vahabi, Matthew Jackson, Bilal Bawamia, Stephanie A. Mack, Karen McLeod, Heather Robinson, Bev Atkinson, Nicola Cunningham, Jeetendra Thambyrajah, Sam Middleton, Nick Cruden, Andrew D. Flapan, Vipin Zamvar, Belinda Rif, J. Harrison, Sharon Lockie, Mohammed Akhtar, Steve Hamshere, Neil Roberts, Mervyn Andiapen, Rita Adrego, Delfin Encarnacion, Jonathan Byrne, Ranjit Deshpande, Max Baghai, Michelle Andrews, Abigail Knighton, James Cotton, Heyman Luckraz, Andy Smallwood, Stella Metherell, Raj Das, Azfar Zaman, Kathryn Proctor, U Nwanjo Harrison, Tito Kabir, Vas Panoulas, Claire Prendergast, Paula Rogers, Shelley Rahman Haley, A. Navaneethakrishnan, Tomasz Spyt, M. Hickey, Elved Roberts, Donna Alexander, Elaine Logtens, Derek Chin, Jeffrey Khoo, Anna-Marie Marsh, John McAdam, Marion Campton, Malcolm Dalrymple‐Hay, Venkat Suresh, Natasha Wilmshurst, Linda Zacharkiw, Christopher Allen, Megan Bell, Karen M. Wilson, M. Alam, Ian Massey, J Wain, Rebecca Griffiths, Will Winder, Robert J. Henderson, Surendra Naik, Adam Szafranek, Kamran Baig, Richard Varcoe, Rachel King, Victoria Kozlowski, Sonia Rubie, Andreas Baumbach, Stephen Dorman, Cha Rajakaruna, Laura Gallego‐Yerga, Sheila M. Bell, Ruth Bowles, Laura Wilkinson, Jo Roberts, Mandie Townsend, David Smith, Aprim Youhana, Alexander Chase, Pankaj Kumar, Gladdys Thomas, Claire Fagan, Jane Griffiths, Alisa Wallis, Bohdana Bahlay, David H. Roberts, Augustine T.M. Tang, Amal Bose, Vasanthi Vasudevan, Peter Groves, Indu Deglurkar, Richard P. Anderson, Vaseem Farooq, Ayush Khurana, Nick Ossei‐Gerning, Dheeraj Mehta, Richard Wheeler, Helen M. Dyer, Julie Edwards, Elizabeth Hodges, Elizabeth D. Thompson, Patricia A. Thomas, Lesley W. Davies, Gillian Andrew, Stephen Hiles, Jacqueline Holder, Sam Bowen, Lona Hanzel, Margaret McEntegart, Nawwar Al‐Attar, Keith G. Oldroyd, Elaine Matthews, Sagar N. Doshi, Jorge Mascaro, Jonathan N. Townend, Aaron M. Ranasinghe, Adnan Nadir, Annette Nilsson, Richard P. Steeds, Richard Lévy, Mamta Buch, Isaac Kadir, Jaydeep Sarma, Saqib Chowdhary, Paul Waterworth, Akhila Muthuswamy, Lindsey McDowell, Cathy Barman, Jane F. Lynch, Anita Macnab, Laura E Dobson, Stephen Brecker, Venkatachalam Chandrasekaran, Vennessa Sookhoo, Raj Sharma, Sue Brown, Ghada Mikhail, Andrew Chukwuemeka, Iqbal Malik, Jon Anderson, Angela Frame, Petros Nihoyannopoulos, Thirumaran Rajathurai, Thomas H. Barker, Luke Tapp, Catherine Gibson, Samantha Hyndman, Luke Mahoney, Laura Speke, Lynn Gardener, Ever Grech, Norman Briffa, Ian P. Hall, Govind Chetty, Stefano Forlani, Mel Neville, Kay Hounsley, Laurence O’Toole, Mark S. Spence, Reuben Jeganathan, Colum Owens, Bernie Smith, Nicola Johnston, Inderpaul Birdi, Rajesh Aggarwal, Madelaine Ocampo, Annaliza Sevillano, Johannes Pintacasi, Mahmoud Loubani, Raj Chelliah, Mubarak Chaudhry, Karen Dobbs, Doug Altman, Tim Daniel, G.J. Fancourt, Marjan Jahangiri, Martin Bland, Dawn E. Saunders, Nicholas A. Boon, Ian B. Wilkinson, Stuart M. Cobbe, Wil Woan, Graham Cooper, John J.V. McMurray, Lars Køber, Peter Crean, Tom Treasure, Ian Ford, Marc Randall, Sanjeev Bhattacharyya, John Dean, Abtehale Al-Hussaini, James S. Yeh, Priyanka Batra, Vicki S Barber, Samuel Fatoba, Surjeet Singh, Elena Villarreal, Mark Butler, Alexis B. Webb, Jim Palmer, Lazarina Engonidou, Aimi Hewitt, Virginia Chiocchia, Beverly A. Shirkey, Susan Dutton, Lei Clifton, Mark Forrest, Gladys McPherson, Brian S. Taylor, Keith Pearce, Martin Stout, Andrew K. Whittaker, Katherine Kuyt, Tiago Vasconcelos Fonseca, William D. Toff, David Hildick‐Smith, Jan Kovac,
Transcatheter aortic valve implantation (TAVI) is a less invasive alternative to surgical aortic valve replacement and is the treatment of choice for patients at high operative risk. The role of TAVI in patients at lower risk is unclear.To determine whether TAVI is noninferior to surgery in patients at moderately increased operative risk.In this randomized clinical trial conducted at 34 UK centers, 913 patients aged 70 years or older with severe, symptomatic aortic stenosis and moderately increased ...
American Medical Association
Produção Nacional
Revisado por pares
Thomas Roux, Mathieu Barbier, Mélanie Papin, Claire-Sophie Davoine, Sabrina Sayah, Giulia Coarelli, Perrine Charles, Cécilia Marelli, Livia Parodi, Christine Tranchant, Cyril Goizet, Stephan Klebe, Ebba Lohmann, Lionel Van Maldergem, Christine Van Broeckhoven, Marie Coutelier, Christelle Tesson, Giovanni Stévanin, Charles Duyckaerts, Alexis Brice, Alexandra Dürr, Alexandra Durr, Giovanni Stévanin, Alexis Brice, Frédéric Darios, Sylvie Forlani, Pitié-Salpêtrière Site, Guillaume Banneau, Cécile Cazeneuve, Perrine Charles, Charles Duyckaerts, Bertrand Fontaine, Jean‐Philippe Azulay, Odile Boesfplug-Tanguy, Cyril Goizet, Didier Hannequin, Jamïlé Hazan, Andrea Burgo, Christophe Verny, M. Kœnig, Pierre Labauge, Cécilia Marelli, Karine N’guyen, Diana Rodriguez, Soraya Belarbi, Abdelmadjid Hamri, Mériem Tazir, Sylvia Boesch, Massimo Pandolfo, Jardim Laura, Velina Guergueltcheva, Ivalo Tournev, Olga Lucia Pedraza Linarès, Jørgen E. Nielsen, Kirsten Svenstrup, Maha S. Zaki, Peter Bauer, Lüdger Schöls, Rebecca Schüle, Alexander Lossos, Maria-Teresa Bassi, Manuela Basso, Enrico Bertini, Alfredo Brusco, Carlo Casali, Giorgio Casari, Chiara Criscuolo, Alessandro Filla, Laura Orsi, Filippo M. Santorelli, Enza Maria Valente, Marinela Vavla, Giovanni Vazza, André Mégarbané, Ali Benomar, Berry Kremer, Willeke M. C. van Roon‐Mom, Richard Roxburgh, Anne Kjersti Erichsen, Chantal Tallaksen, Isabel Alonso, Paula Coutinho, José Léal Loureiro, Jorge Sequeiros, Mustapha Salih, Vladimir Kostić, Idoia Rouco Axpe, Liena E. O. Elsayed, Martin Paucar, Samir Roumani, Soong Bing-Wen, Evan Reid, Suran Nethisinghe, Thomas T. Warner, Nicholas Wood,
Pathogenic variants in STUB1 were initially described in autosomal recessive spinocerebellar ataxia type 16 and dominant cerebellar ataxia with cerebellar cognitive dysfunction (SCA48).We analyzed a large series of 440 index cerebellar ataxia cases, mostly with dominant inheritance.STUB1 variants were detected in 50 patients. Age at onset and severity were remarkably variable. Cognitive impairment, predominantly frontal syndrome, was observed in 54% of STUB1 variant carriers, including five families ...
Tópico(s): Neurological diseases and metabolism
2020 - Elsevier BV | Genetics in Medicine
Stéphanie Paradis, Miriam Forlani, Britanny Blachot‐Minassian, Sophie Bouyon, Guillaume Vial, Jean‐Louis Pépin, Claire Arnaud, Elise Belaïdi,
Obstructive sleep apnea (OSA) affects 1 billion people worldwide. Its main feature is chronic intermittent hypoxia (IH), responsible for metabolic and cardiovascular (CV) diseases. Type 2 diabetes is highly prevalent in OSA patients and is also recognized to be an independent CV risk factor. The multi-pathologic status of OSA patients partially explains why the gold standard treatment of OSA fails to decrease CV events. Here, we aim at suggest new strategies against OSA-associated comorbidities, based ...
Tópico(s): Hydrogen's biological and therapeutic effects
2024 - Elsevier BV | Archives of cardiovascular diseases
... entry by Palladino), 114–15, repr. (colour); Anna Forlani Tempesti, no. 64, as ‘A follower of Fra ...
Tópico(s): Renaissance and Early Modern Studies
2023 - Taylor & Francis | Word & Image
Produção Nacional
Revisado por pares
Thomas Roux, Mathieu Barbier, Mélanie Papin, Claire-Sophie Davoine, Sabrina Sayah, Giulia Coarelli, Perrine Charles, Cécilia Marelli, Livia Parodi, Christine Tranchant, Cyril Goizet, Stephan Klebe, Ebba Lohmann, Lionel Van Maldergem, Christine Van Broeckhoven, Marie Coutelier, Christelle Tesson, Giovanni Stévanin, Charles Duyckaerts, Alexis Brice, Alexandra Dürr, Alexandra Dürr, Giovanni Stévanin, Alexis Brice, Frédéric Darios, Sylvie Forlani, Pitié-Salpêtrière Site, Guillaume Banneau, Cécile Cazeneuve, Perrine Charles, Charles Duyckaerts, Bertrand Fontaine, Jean‐Philippe Azulay, Odile Boesfplug-Tanguy, Cyril Goizet, Didier Hannequin, Jamïlé Hazan, Andrea Burgo, Christophe Verny, Michel Kœnig, Pierre Labauge, Cécilia Marelli, Karine Nguyen, Diana Rodriguez, Soraya Belarbi, Abdelmadjid Hamri, Meriem Tazir, Sylvia Boesch, Massimo Pandolfo, Jardim Laura, Velina Guergueltcheva, Ivalo Tournev, Olga Lucia Pedraza Linarès, Jørgen E. Nielsen, Kirsten Svenstrup, Maha S. Zaki, Peter Bauer, Lüdger Schöls, Rebecca Schüle, Alexander Lossos, Maria-Teresa Bassi, Manuela Basso, Enrico Bertini, Alfredo Brusco, Carlo Casali, Giorgio Casari, Chiara Criscuolo, Alessandro Filla, Laura Orsi, Filippo M. Santorelli, Enza Maria Valente, Marinela Vavla, Giovanni Vazza, André Mégarbané, Ali Benomar, Berry Kremer, Willeke M. C. van Roon‐Mom, Richard Roxburgh, Anne Kjersti Erichsen, Chantal Tallaksen, Isabel Alonso, Paula Coutinho, José L. Loureiro, Jorge Sequeiros, Mustapha Salih, Vladimir Kostić, Idoia Rouco Axpe, Liena E. O. Elsayed, Martin Paucar, Samir Roumani, Soong Bing-Wen, Evan Reid, Suran Nethisinghe, Thomas T. Warner, Nicholas Wood,
A Correction to this paper has been published: https://doi.org/10.1038/s41436-020-01064-y
Tópico(s): Mitochondrial Function and Pathology
2020 - Elsevier BV | Genetics in Medicine