Cedric Francois, Warren C. Breidenbach, Claudio Maldonado, Thanos P. Kakoulidis, Anne Hodges, Jean‐Michel Dubernard, Earl Owen, Guoxain Pei, Xiaoping Ren, John H. Barker,
... Louisville, KentuckySearch for more papers by this authorClaudio Maldonado Ph.D., Claudio Maldonado Ph.D. Divisions of Plastic and Reconstructive ... Louisville, KentuckySearch for more papers by this authorClaudio Maldonado Ph.D., Claudio Maldonado Ph.D. Divisions of Plastic and Reconstructive Surgery ...
Tópico(s): Reconstructive Facial Surgery Techniques
2000 - Wiley | Microsurgery
Produção Nacional
Revisado por pares
Mario H. Cardiel, Enrique R. Soriano, Eloísa Bonfá, Graciela S. Alarcón, Ariel Izcovich, Mary Carmen Amigo Castañeda, Leonor Barile-Fabris, Margarita Duarte, Graciela Espada, Mercedes García, Roger A. Levy, Loreto Massardo, Emília Inoue Sato, Gloria Vásquez, Eduardo M. Acevedo‐Vásquez, Luís J. Catoggio, R. Chacón, Claudio M. Galarza Maldonado, Antonio J. Iglesias Gamarra, José Fernando Molina Restrepo, Óscar Neira, Clóvis A. Silva, Andrea Vargas Peña, Bernardo A. Pons‐Estel,
... J. MD, PhD†††; Chacón-Díaz, Rosa MD‡‡‡; Galarza Maldonado, Claudio M. MD, PhD§§§; Iglesias Gamarra, Antonio J. MD∥∥∥; ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2017 - Lippincott Williams & Wilkins | JCR Journal of Clinical Rheumatology
John G. Van Savage, Gustavo Perez‐Abadia, L G Palanca, Janou W. J. M. Bardoel, Thomas Harralson, Bruce L. Slaughenhoupt, Martin M. Palacio, Gordon R. Tobin, Claudio Maldonado, John H. Barker,
... L. SLAUGHENHOUPT, MARTIN M. PALACIO, GORDON R. TOBIN, CLAUDIO MALDONADO, and JOHN H. BARKER JOHN G. VAN SAVAGEJOHN ... GORDON R. TOBIN More articles by this author CLAUDIO MALDONADO More articles by this author JOHN H. BARKER ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2000 - Lippincott Williams & Wilkins | The Journal of Urology
Jorge Higinio Maldonado, Claudio González‐Vega,
Channels for the influence of microfinance programs on a rural household's demand for schooling are identified: income growth, risk management, child-labor demand, gender empowerment, and parent information. Within a random-utility framework, a model of household consumption, investment in education, and borrowing suggests determinants at the individual, household and regional levels of the probability of schooling gaps. Using data from two surveys of households of clients of microfinance organizations ...
Tópico(s): Agricultural risk and resilience
2008 - Elsevier BV | World Development
Sebastián Maldonado, Claudio Montecinos,
200 words for Intelligent Data Systems The class imbalance problem is a relatively new challenge that has attracted growing attention from both industry and academia, since it strongly affects classification performance. Research also established tha
Tópico(s): Electricity Theft Detection Techniques
2014 - IOS Press | Intelligent Data Analysis
Jaime Pizarro, Erick Flores, Víctor M. Jiménez, Tamara Maldonado, Claudio Saitz, Andrés Vega, Fernando Godoy, Rodrigo Segura,
An electrochemical sensor for the determination of Cu(II) in bivalve mollusks using a glassy carbon electrode modified with p-tert-butylcalix [4]arene-bis-cyrhetrenylimine (Cy2(Calix [4])) by square wave anodic stripping voltammetry (SWASV) has been developed. The organometallic compound was synthesized from cyrhetrene-carboxaldehyde and 25,26-bis-(2-aminoethoxy)-26,28-dihydrocalix [4]arene through a condensation reaction. Metalloligand (Cy2(Calix [4])) was characterized by FT-IR and 1H-13C 2D NMR spectroscopies ...
Tópico(s): Analytical Chemistry and Sensors
2018 - Elsevier BV | Sensors and Actuators B Chemical
Carla Vairetti, Rosa G. González‐Ramírez, Sebastián Maldonado, Claudio Álvarez, Stefan Voβ,
Inter-Organizational Information Systems (IOISs) for seaport logistics facilitate monitoring operations, the exchange of information with stakeholders, and meeting regulations of foreign trade. However, seaport contexts entail complexities in terms of stakeholder involvement and business processes that must be considered thoroughly toward the successful adoption of IOISs. This research seeks to identify factors influencing the successful adoption of IOISs in seaports. It follows a grounded theory ...
Tópico(s): Law, logistics, and international trade
2019 - Elsevier BV | Transportation Research Part A Policy and Practice
Gabriela Carrasco‐Puga, Francisca P. Díaz, Daniela C. Soto, Catalina Hernández‐Castro, Orlando Contreras‐López, Antonio Maldonado, Claudio Latorre, Rodrigo A. Gutiérrez,
Estimating total plant diversity in extreme or hyperarid environments can be challenging, as adaptations to pronounced climate variability include evading prolonged stress periods through seeds or specialized underground organs. Short‐term surveys of these ecosystems are thus likely poor estimators of actual diversity. Here we develop a multimethod strategy to obtain a more complete understanding of plant diversity from a community in the Atacama Desert. We explicitly test environmental DNA‐based ...
Tópico(s): Genomics and Phylogenetic Studies
2020 - Wiley | Ecography
Nathalie Kühn, Jonathan Maldonado, Claudio Ponce, Macarena Arellano, Alson Time, Salvatore Multari, Stefan Martens, Esther Carrera, José Manuel Donoso, Boris Sagredo, Lee A. Meisel,
Abstract Gibberellin (GA) negatively affects color evolution and other ripening-related processes in non-climacteric fruits. The bioactive GA, gibberellic acid (GA 3 ), is commonly applied at the light green-to-straw yellow transition to increase firmness and delay ripening in sweet cherry ( Prunus avium L.), though causing different effects depending on the variety. Recently, we reported that GA 3 delayed the IAD parameter (a ripening index) in a mid-season variety, whereas GA 3 did not delay IAD but reduced ...
Tópico(s): Plant Physiology and Cultivation Studies
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Juberlan Silva Garcia, Arnaldo Maldonado, Claudio J. Bidau, Ligia dos Reis Corrêa, R. M. Lanfredi, Paulo Marcos Zech Coelho,
Infection caused by the trematode Echinostoma paraensei has been shown to interfere in the natural resistance to infection by Schistosoma mansoni.Biomphalaria glabrata is susceptible to infection, while Taim isolate Biomphalaria tenagophila is resistant to infection by S. mansoni.These two snail species were assessed for infection with E. paraensei two days after exposure to S. mansoni miracidia.The number of B. tenagophila and B. glabrata infected with E. paraensei was lower in co-infected group, ...
Tópico(s): Helminth infection and control
2010 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Roberto Maldonado, Claudio Rosa, Klaus I. Pedersen,
In this paper, the achievable latency-reliability performance of a standalone cellular network over the 5 GHz unlicensed spectrum is analysed. Fulfilling strict latency-reliability requirements comes with significant challenges for unlicensed operation, especially due to mandatory channel access procedures. Using MulteFire as the reference system-model, an analysis of a highly realistic multi-cell network with bi-directional traffic shows that latency of 23 ms with a reliability level of 99.99% ...
Tópico(s): Advanced Wireless Communication Techniques
2020 - Institute of Electrical and Electronics Engineers | IEEE Access
Humberto Coto, Claudio Maldonado, Prasad R. Palakurthy, Nancy C. Flowers,
Fifty normal male and female athletes, or athletically active subjects, were evaluated, and a search for low-amplitude late potentials in the terminal part of ventricular activation was performed. Recordings from 3 normal men met the definition of abnormal late potentials, and were indistinguishable by present analytic techniques from those encountered in patients who have ventricular tachycardia (VT) after myocardial infarction (MI). Of 24 patients studied, 11 had VT, but only 2 had had an MI, which ...
Tópico(s): ECG Monitoring and Analysis
1985 - Elsevier BV | The American Journal of Cardiology
Shuichi Hiromasa, Takayuki Ikeda, Kouji Kubota, Nobutaka Hattori, Masao Nishimura, Yoshio Watanabe, Claudio Maldonado, Prasad R. Palakurthy, Joel Kupersmith,
Myotonic dystrophy is frequently associated with functional and anatomic derangements in the myocardium. Ten myotonic dystrophy patients (seven men and three women, ages ranging from 35 to 58 years) were evaluated with a 12-lead ECG, 24-hour Holter monitor recording, invasive electrophysiologic studies, and echocardiographic examination. Nine patients displayed abnormalities in the conduction system. ECG and Holter monitor abnormalities were first-degree atrioventricular block (n = 8), second-degree ...
Tópico(s): Neurology and Historical Studies
1987 - Elsevier BV | American Heart Journal
Shuichi Hiromasa, Humberto Coto, Zhen-Yuan Li, Claudio Maldonado, Joel Kupersmith,
The dextrorotatory isomer of sotalol (d-sotalol) has class III antiarrhythmic properties with known action potential duration (APD) prolonging effects, and is largely devoid of beta-adrenergic blocking activity. We studied its electrophysiologic effects and the mechanism of its APD prolonging effects in sheep Purkinje fibers by means of standard microelectrode techniques. At all concentrations (10(-6) to 10(-4) mol/L), d-sotalol had no effect on Vmax. At 10(-6) mol/L, d-sotalol had no effect on APD. ...
Tópico(s): Electrochemical Analysis and Applications
1988 - Elsevier BV | American Heart Journal
Shuichi Hiromasa, Takayuki Ikeda, Kouji Kubota, Nobutaka Hattori, Humberto Coto, Claudio Maldonado, Joel Kupersmith,
Myotonic Dystrophy type 1 (DM1) is a multisystemic disease, autosomal dominant, caused by a CTG repeat expansion in DMPK gene.We assessed the appropriateness of patient-specific induced pluripotent stem cell-derived cardiomyocytes (CMs) as a model to recapitulate some aspects of the pathogenetic mechanism involving cardiac manifestations in DM1 patients.Once obtained in vitro, CMs have been characterized for their morphology and their functionality. CMs DM1 show intranuclear foci and transcript markers ...
Tópico(s): Mitochondrial Function and Pathology
1988 - Elsevier BV | American Heart Journal
Claudio Maldonado Rivera, Ned C. Ahlberg, Lauren Taglia, Mayank Kumar, Adam Blunier, Richard V. Benya,
Tópico(s): Neuropeptides and Animal Physiology
2009 - Springer Science+Business Media | Clinical & Experimental Metastasis
Z.-Y. Li, Claudio Maldonado, Christopher Zee-Cheng, Shuichi Hiromasa, Joel Kupersmith,
Previous studies have attempted to characterise the genesis of triggered activity related to early afterdepolarisations. Little is known about their conduction behaviour. This study was designed to examine the origin and conduction behaviour of triggered activations to throw light on the pathogenesis of torsade de pointes.Electrophysiological interactions related to triggered activations and early afterdepolarisations between papillary muscle and Purkinje fibres were studied in the guinea pig in ...
Tópico(s): Muscle activation and electromyography studies
1992 - Oxford University Press | Cardiovascular Research
John H. Barker, Cedric Francois, Johannes Frank, Claudio Maldonado,
INTRODUCTION On May 17–18, 2000, the Second International Symposium on Composite Tissue Allotransplantation took place in Louisville, KY. We summarize the work presented at this historical meeting and in doing so provide the reader with an overview of the latest developments in the field of clinical composite tissue allotransplantation (CTA). The concept of transplanting tissues for restoration of acquired or congenital deformities is not new. In fact, the first account of transplanting tissue from ...
Tópico(s): Organ Donation and Transplantation
2002 - Wolters Kluwer | Transplantation
Rafael Fernandez-Botrán, Vijay S. Gorantla, Xichun Sun, Xiaoping Ren, Gustavo Perez‐Abadia, Fabián Crespo, Robert Oliver, Haldun Orhun, Edwin E. Quan, Claudio Maldonado, Mukunda B. Ray, John H. Barker,
Background. Glycosaminoglycans (GAGs) are heteropolysaccharides present as integral components of the extracellular matrix (ECM), cell and basement membranes. GAGs play an important role in immune and inflammatory responses because of their ability to interact with cytokines and chemokines, promoting the localization of these molecules onto the ECM or cell membranes at specific anatomical sites. The main goal of these studies was to test the hypothesis that interference with the binding of cytokines/ ...
Tópico(s): Transplantation: Methods and Outcomes
2002 - Wolters Kluwer | Transplantation
Gustavo Perez‐Abadia, Luis A. Laurentin-Perez, Vijay S. Gorantla, Cedric Francois, Marieke Vossen, Pascal C. R. Brouha, Haldun Orhun, Gary L. Anderson, Claudio Maldonado, Diane J. Pidwell, Warren C. Breidenbach, John H. Barker,
Composite tissue allografts (CTAs) offer an alternative to conventional reconstructive methods. However, the toxicity of the drugs that are required to prevent rejection has prevented its widespread clinical application. The purpose of this study was to determine whether a low-dose, corticosteroid-free combination regimen of tacrolimus and mycophenolate mofetil (MMF) would prevent rejection in a rat hind-limb model, with minimal toxic side effects. Three groups were used in this study. In group I, ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2002 - Springer Science+Business Media | Transplant International
Kaustubha A. Prabhune, Vijay S. Gorantla, Gustavo Perez‐Abadia, Cedric Francois, Marieke Vossen, Luis A. Laurentin-Perez, Warren C. Breidenbach, Gordon G. Wang, Gary L. Anderson, Diane J. Pidwell, John H. Barker, Claudio Maldonado,
Background. We and others have shown that mixed allogeneic chimerism induces donor-specific tolerance to composite tissue allografts across major histocompatibility complex barriers without the need for immunosuppression. However, a delay period between bone marrow transplantation and limb allotransplantation is required, making such protocols impractical for clinical application. This study eliminates this delay period in a rat hind limb allotransplantation model by performing mixed allogeneic ...
Tópico(s): Transplantation: Methods and Outcomes
2003 - Wolters Kluwer | Transplantation
Claudio Maldonado, Wayne K. Stadelmann, Santiago Ramírez, Edwin E. Quan, John H. Barker,
The use of dynamic myoplasty to restore function to failing organs is an exciting new application of skeletal muscle flaps. A complication of large flap elevation that can compromise flap function is ischemia-induced necrosis; one approach to minimizing this is to pretreat tissues with ischemic preconditioning. The purpose of this study was to determine whether systemic administration of monophosphoryl lipid A, a drug known to mimic latephase ischemic preconditioning in the heart, could reduce ischemia- ...
Tópico(s): Anesthesia and Neurotoxicity Research
2003 - Lippincott Williams & Wilkins | Plastic & Reconstructive Surgery
Vijay S. Gorantla, Kaustubha A. Prabhune, Gustavo Perez‐Abadia, Suzanne T. Ildstad, Claudio Maldonado, Haldun Orhun, Ramsey K. Majzoub, Cedric Francois, Thanos P. Kakoulidis, Pascal C. R. Brouha, Gary L. Anderson, Diane J. Pidwell, Warren C. Breidenbach, John H. Barker,
Background. Mixed allogeneic chimerism (MAC) has been shown to induce tolerance to composite tissue allografts (CTA). However, transplantation of unmanipulated donor-specific limbs results in severe graft-versus-host disease (GVHD). This suggests that nontolerant mature donor-derived cells in the CTA may affect the stability of chimerism, potentially resulting in GVHD. The aim of this study was to develop an approach to study and prevent GVHD in a mixed chimeric-rat hind-limb transplantation model. ...
Tópico(s): Biomedical Ethics and Regulation
2003 - Wolters Kluwer | Transplantation
Gustavo Perez‐Abadia, Luis A. Laurentin-Perez, Vijay S. Gorantla, Cedric Francois, Marieke Vossen, Pascal C. R. Brouha, Haldun Orhun, Gary L. Anderson, Claudio Maldonado, Diane J. Pidwell, Warren C. Breidenbach, John H. Barker,
Composite tissue allografts (CTAs) offer an alternative to conventional reconstructive methods. However, the toxicity of the drugs that are required to prevent rejection has prevented its widespread clinical application. The purpose of this study was to determine whether a low-dose, corticosteroid-free combination regimen of tacrolimus and mycophenolate mofetil (MMF) would prevent rejection in a rat hind-limb model, with minimal toxic side effects. Three groups were used in this study. In group I, ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2003 - Springer Science+Business Media | Transplant International
Michael J. Sundine, Edwin E. Quan, Ozlen Saglam, Vikas Dhawan, Peter M. Quesada, Lynn Ogden, Thomas Harralson, M. Douglas Gossman, Claudio Maldonado, John H. Barker,
Facial paralysis is a serious neurologic disorder, particularly when it affects the eye. Loss of the protective blink reflex may lead to corneal ulceration and, possibly, visual loss. The purpose of this study was to compare different nerve-grafting techniques to reanimate the paralyzed eyelid. Sixteen adult dogs (25 kg each) were allocated into four groups. Denervation of the left hemi-face was performed in all cases. One dog served as a control animal (group I). Group II dogs (n = 5) underwent end- ...
Tópico(s): Ocular Disorders and Treatments
2003 - Lippincott Williams & Wilkins | Plastic & Reconstructive Surgery
Joel Kupersmith, Zhenyuan Li, Claudio Maldonado,
The objective of this study was to delineate electrophysiologic phenomena in a border zone adjacent to a zone of marked action potential prolongation. By means of a standard microelectrode technique, we studied sheep Purkinje fibers placed in a partitioned chamber and superfused with Tyrode's solution. Ethylenediame tetraacetic acid (EDTA) was added to one chamber. Recordings were made in the abnormal segment (ABN) superfused with EDTA and at two sites in the normal segment (NL)—at the border within ...
Tópico(s): Ion channel regulation and function
1994 - Elsevier BV | American Heart Journal
Z.-Y. Li, Y.-h. Wang, Claudio Maldonado, Joel Kupersmith,
Objective: The aim was to examine under abnormal conditions the flow of currents across junctional (J-) cells found between Purkinje fibre cells and ventricular muscle cells, and determine whether these currents play a role in increasing the excitation rate of ventricular muscle. Methods: Canine Purkinje fibre and papillary muscle preparations were mapped to locate the Purkinje fibre-ventricular muscle cell junction (PVJ). Using standard techniques, action potentials from Purkinje fibres, J-cells, ...
Tópico(s): Ion channel regulation and function
1994 - Oxford University Press | Cardiovascular Research
Sathnur Pushpakumar, Gustavo Perez‐Abadia, Chirag Soni, Rong Wan, Nathan Todnem, Phani K. Patibandla, Tathyana Fensterer, Qunwei Zhang, John H. Barker, Claudio Maldonado,
Excessive complement activation is an integral part of ischemia and reperfusion (IR) injury (IRI) of organs. In kidney transplantation, the pathologic consequence of IRI and complement activation can lead to delayed graft function, which in turn is associated with acute rejection. Previous strategies to reduce complement-induced IRI required systemic administration of agents, which can lead to increased susceptibility to infections/immune diseases. The objective of this study was to determine whether ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2011 - Elsevier BV | Journal of Surgical Research
Robert Tell, Claudio Maldonado Rivera, Jillian N. Eskra, Lauren Taglia, Adam Blunier, Q. Tian Wang, Richard V. Benya,
Epithelial cells lining the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR). In contrast, GRP/GRPR can be aberrantly expressed in colon cancer where they are associated with improved patient survival rates. However, the mechanism of action whereby these proteins mediate their beneficial effects is not known. Heterochromatin protein 1 is an epigenetic modifier of gene transcription for which three different isoforms exist in humans: HP1(Hsα), HP1(Hsβ), and ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2011 - Elsevier BV | American Journal Of Pathology
Brian Gander, Charles S. Brown, Dalibor Vasilic, Allen Furr, Joseph C. Banis, Michael Cunningham, Osborne P. Wiggins, Claudio Maldonado, Iain S. Whitaker, Gustavo Perez‐Abadia, Johannes Frank, John H. Barker,
Each year an estimated 7-million people in the USA need composite tissue reconstruction because of surgical excision of tumors, accidents and congenital malformations. Limb amputees alone comprise over 1.2 million of these. This figure is more than double the number of solid organs needed for transplantation. Composite tissue allotransplantation in the form of hand and facial tissue transplantation are now a clinical reality. The discovery, in the late 1990s, that the same immunotherapy used routinely ...
Tópico(s): Reconstructive Surgery and Microvascular Techniques
2006 - Springer Science+Business Media | Transplant International