Carlo Nucci, Claudio Cedrone, Franco Culasso, Massimo Cesareo, Federico Regine, L Cerulli,
Tópico(s): Ophthalmology and Visual Impairment Studies
2004 - Springer Science+Business Media | Graefe s Archive for Clinical and Experimental Ophthalmology
Carlo Nucci, Claudio Cedrone, Franco Culasso, Federico Ricci, Massimo Cesareo, A Corsi, L Cerulli,
To study the incidence of visual loss over a 12-year period in the survivors of an original cohort aged 40 years or older at baseline.Visual acuity (VA) was measured by means of a standardized logMAR chart. World Health Organization definition of blindness and low vision was adopted (respectively, best-corrected VA >1.3 logMAR or a visual field 0.5-1.3 logMAR or a visual field 0.5 logMAR) was calculated in a 'healthy' group who had uncorrected VA of 0.0 logMAR or better in both eyes at baseline and ...
Tópico(s): Ophthalmology and Visual Impairment Studies
2004 - Springer Nature | Eye
Gianluca Nucci, Claudio Cobelli,
Tópico(s): Metabolism, Diabetes, and Cancer
2000 - Elsevier BV | Computer Methods and Programs in Biomedicine
Riccardo Bellazzi, Gianluca Nucci, Claudio Cobelli,
Discusses closed-loop and partially closed-loop control strategies for insulin delivery and measuring glucose concentration. The authors review the subcutaneous closed- and partially closed-loop strategies that have been proposed and tested in recent years for insulin-dependent diabetes therapy. Focus is on control, modeling, and information technology aspects, and future directions of research are also outlined. This survey complements earlier reviews concerning control approaches and application ...
Tópico(s): Receptor Mechanisms and Signaling
2001 - IEEE Engineering in Medicine and Biology Society | IEEE Engineering in Medicine and Biology Magazine
... predisposed individualsMerri Pendergrass, Alessandra Bertoldo, Riccardo Bonadonna, Gianluca Nucci, Lawrence Mandarino, Claudio Cobelli, and Ralph A. DeFronzo1 January 2007 | American ...
Tópico(s): Metabolism, Diabetes, and Cancer
1990 - American Physiological Society | Physiological Reviews
Gianluca Nucci, Simonluca Tessarin, Claudio Cobelli,
In this study we propose, and implement in the time domain, an anatomically consistent model of the respiratory system in critical care conditions that allows us to evaluate the impact of different ventilator strategies as well as of constrictive pathologies on the time course of acinar pressures and flows. We discuss the simplifications of the original Horsfield structure (Horsfield, K., [et_al.] Models of the human bronchial tree. J. Appl. Physiol. 31:207–217, 1971), which were needed to enable ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2002 - Springer Science+Business Media | Annals of Biomedical Engineering
Produção Nacional
Revisado por pares
Gabriela Salim de Castro, Joanna D.C.C. Lima, Estefanía Simoes, Camila E. Orsso, Jingjie Xiao, Leonardo R. Gama, Sílvio Pires Gomes, Daniela Caetano Gonçalves, Raquel Costa, Katrin Radloff, U Lenz, Anna E. Taranko, Fang Chia Bin, Fernanda Bellotti Formiga, Louisie Galantini Lana de Godoy, Rafael Pereira de Souza, Luis H.A. Nucci, Mario Feitoza, Claudio Campi de Castro, Flávio Tokeshi, Paulo Sérgio Martins de Alcântara, José Pinhata Otoch, Alexandre F. Ramos, Alessandro Laviano, Dario Coletti, Vera C. Mazurak, Carla M. Prado, Marília Seelaender,
Cancer-associated cachexia is a complex metabolic syndrome characterized by weight loss and systemic inflammation. Muscle loss and fatty infiltration into muscle are associated with poor prognosis in cancer patients. Skeletal muscle secretes myokines, factors with autocrine, paracrine and/or endocrine action, which may be modified by or play a role in cachexia. This study examined myokine content in the plasma, skeletal muscle and tumor homogenates from treatment-naïve patients with gastric or colorectal ...
Tópico(s): Adipose Tissue and Metabolism
2020 - Elsevier BV | Clinical Nutrition
Merri Pendergrass, Alessandra Bertoldo, Riccardo C. Bonadonna, Gianluca Nucci, Lawrence J. Mandarino, Claudio Cobelli, Ralph A. DeFronzo,
Our objectives were to quantitate insulin-stimulated inward glucose transport and glucose phosphorylation in forearm muscle in lean and obese nondiabetic subjects, in lean and obese type 2 diabetic (T2DM) subjects, and in normal glucose-tolerant, insulin-resistant offspring of two T2DM parents. Subjects received a euglycemic insulin (40 mU·m −2 ·min −1 ) clamp with brachial artery/deep forearm vein catheterization. After 120 min of hyperinsulinemia, a bolus of d-mannitol/3- O-methyl-d-[ 14 C]glucose/d-[ ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2006 - American Physiological Society | AJP Endocrinology and Metabolism
Produção Nacional
Revisado por pares
Cristiana M. Toscano, Bruce Bartholow Duncan, Sotero Serrate Mengue, Carísi Anne Polanczyk, Luciana Bertoldi Nucci, Adriana Costa e Forti, Cláudio Duarte Fonseca, María Inês Schmidt,
In 2001 Brazilian citizens aged 40 or older were invited to participate in a nationwide population screening program for diabetes. Capillary glucose screening tests and procedures for diagnostic confirmation were offered through the national healthcare system, diagnostic priority being given according to the severity of screening results. The objective of this study is to evaluate the initial impact of the program. Positive testing was defined by a fasting capillary glucose ≥ 100 mg/dL or casual glucose ≥ ...
Tópico(s): Diabetes Management and Research
2008 - BioMed Central | BMC Health Services Research
Riccardo Bellazzi, Cristiana Larizza, Stefania Montani, Alberto Riva, Mario Stefanelli, Giuseppe d’Annunzio, Renata Lorini, Enrique J. Gómez Aguilera, M. Elena Hernando, Eulàlia Brugués, Julman Cermeño, Rosa Corcoy, Alberto de Leiva, Claudio Cobelli, Gianluca Nucci, Stefano Del Prato, Alberto Maran, E Kilkki, JuhaA. Tuominen,
In the context of the EU funded Telematic Management of Insulin-Dependent Diabetes Mellitus (T-IDDM) project, we have designed, developed and evaluated a telemedicine system for insulin dependent diabetic patients management. The system relies on the integration of two modules, a Patient Unit (PU) and a Medical Unit (MU), able to communicate over the Internet and the Public Switched Telephone Network. Using the PU, patients are allowed to automatically download their monitoring data from the blood ...
Tópico(s): Mobile Health and mHealth Applications
2002 - Elsevier BV | Computer Methods and Programs in Biomedicine
Claudio Cedrone, Carlo Nucci, Gianluca Scuderi, Federico Ricci, Angelica Cerulli, Franco Culasso,
The scientific literature contains recent data on the prevalence of blindness and low vision for a few European countries, but most of these studies have been focused exclusively on the elderly sector of the populations. The purpose of the present study was to provide age-specific estimates of the prevalence and causes of visual loss in an Italian population aged 40 years and over.In total, 847 of the 1,200 citizens >40 years of age (70.6%) in the island community of Ponza underwent complete standardized ...
Tópico(s): Glaucoma and retinal disorders
2005 - Springer Nature | Eye
Federico Regine, Gianluca Scuderi, Massimo Cesareo, Federico Ricci, Claudio Cedrone, Carlo Nucci,
Abstract Using Goldmann applanation tonometry (GAT) as a gold standard, we evaluated the accuracy of Nidek NT‐4000 pneumotonometry (NPT) in adults without corneal disease. Bland and Altman analysis of serial intra‐ocular pressures (IOPs) measured with NPT and GAT in 10 healthy subjects revealed that the repeatability coefficients for the two methods were similar. NPT, GAT and ultrasonic pachymetry were then performed in 100 patients. Bland and Altman analysis showed that NPT yielded significantly higher ...
Tópico(s): Ocular Surface and Contact Lens
2005 - Wiley | Ophthalmic and Physiological Optics
Angelica Cerulli, Massimo Cesareo, Elena Ciuffoletti, Maria Montanaro, Raffaele Mancino, Concetta Mirisola, Roberto Sorge, Claudio Cedrone, Carlo Nucci, L Cerulli,
Purpose To assess eye movements pattern during reading process in patients with primary open-angle glaucoma (POAG) using a microperimeter. Methods Thirty-two patients with POAG at early and moderate stage, according to Glaucoma Staging System 2, and 34 healthy age- and sex-matched subjects were included in the study. Reading speed and accuracy were previously evaluated with specific tests adjusted for age. In addition, all participants performed a reading test with Microperimeter Nidek MP1. Ocular ...
Tópico(s): Neurological Disorders and Treatments
2013 - SAGE Publishing | European Journal of Ophthalmology
Produção Nacional
Revisado por pares
Luciana Bertoldi Nucci, Cristiana M. Toscano, Ana Lourdes M. Maia, Cláudio Duarte Fonseca, Maria Moema B. Britto, Bruce Bartholow Duncan, María Inês Schmidt,
OBJECTIVES: In 2001, persons throughout Brazil who were 40 years old or older were invited to participate in community screening for diabetes as part of the Brazilian Ministry of Health's Plan for the Reorganization of Care for Arterial Hypertension and Diabetes Mellitus. This report describes the overall participation rate and positivity rate of the screening campaign, as well as factors associated with the level of participation among the municipalities in Brazil. METHODS: Screening test positivity ...
Tópico(s): Diabetes Management and Education
2004 - Pan American Health Organization | Revista Panamericana de Salud Pública
Gianluca Nucci, M Mergoni, C. Bricchi, Guido Polese, Claudio Cobelli, Andrea Rossi,
Measurement of the intrinsic positive end-expiratory pressure (PEEP i ) is important in planning the management of ventilated patients. Here, a new recursive least squares method for on-line monitoring of PEEP i is proposed for mechanically ventilated patients. The procedure is based on the first-order model of respiratory mechanics applied to experimental measurements obtained from eight ventilator-dependent patients ventilated with four different ventilatory modes. The model PEEP i (PEEP i,mod ) was ...
Tópico(s): Neonatal Respiratory Health Research
2000 - American Physiological Society | Journal of Applied Physiology
Gian Eugenio Tontini, Luca Pastorelli, Luisa Spina, F Fabris, Barbara Bruni, Claudio Clemente, Germana De Nucci, Flaminia Cavallaro, Stefano Marconi, Markus F. Neurath, Helmut Neumann, Milena Tacconi, Maurizio Vecchi,
Lymphocytic and collagenous colitis are emerging as common findings in subjects undergoing colonoscopy for chronic non-bloody diarrhea (CNBD). Data concerning microscopic colitis (MC) are still limited and affected by controversial epidemiological evidences. Recent converging lines of evidence suggest that MC correlates a lower risk of colorectal neoplasia. Accordingly, we prospectively assessed MC prevalence in a multicenter cohort of subjects submitted to colonoscopy for CNBD, thereby defining whether ...
Tópico(s): Intestinal and Peritoneal Adhesions
2014 - Oxford University Press | Inflammatory Bowel Diseases
Raffaele Pezzilli, Elisabetta Buscarini, Tommaso Pollini, Deborah Bonamini, Giovanni Marchegiani, Stefano Crippa, Giulio Belfiori, Cosimo Sperti, Lucia Moletta, G Pozza, Germana De Nucci, G. Manes, Enzo Domenico Mandelli, Riccardo Casadei, Claudio Ricci, Saverio Alicante, C. Vattiato, Silvia Carrara, Milena Di Leo, Carlo Fabbri, S. Giovanelli, Luca Barresi, Matteo Tacelli, V.G. Mirante, Rita Conigliaro, Filippo Antonini, Giampiero Macarri, Luca Frulloni, Giulia De Marchi, Romano Sassatelli, Paolo Cecinato, G. Del Vecchio Blanco, Andrea Galli, Angelo Maria Pezzullo, Alberto Fantin, Massimo Graffeo, Mauro Frego, D. Stillittano, Fabio Monica, Bastianello Germanà, Gabriele Capurso, Mariano Quartini, Luigi Veneroni, Renato Cannizzaro, Massimo Falconi,
Introduction A prospective survey to evaluate the diagnostic workup of cystic pancreatic neoplasms (CPNs) according to the Italian guidelines. Methods An online data sheet was built. Results Fifteen of the 1385 patients (1.1%) had non cystic neoplastic lesions. Forty percent (518/1295) had at least one 1st degree relative affected by a solid tumor of the digestive and extra-digestive organs. Symptoms/signs associated with the cystic lesion were present in 24.5% of the patients. The cysts were localized ...
Tópico(s): Gastrointestinal disorders and treatments
2020 - Elsevier BV | Digestive and Liver Disease
Produção Nacional
Revisado por pares
Leonel Lagunes, Bárbara Borgatta, María Teresa Martín-Gómez, Anna Rey-Perez, Massimo Antonelli, Elda Righi, Maria Merelli, Pierluigi Brugnaro, George Dimοpoulos, José Garnacho‐Montero, Arnaldo Lopes Colombo, Roberto Luzzati, Francesco Menichetti, Patricia Muñóz, Márcio Nucci, Giovanni Scotton, Claudio Viscoli, M. Tumbarello, Matteo Bassetti, Jordi Rello, Filippo Ansaldi, Claudio Scarparo, Ana Díaz‐Martín, Inmaculada Palacios-García, Chiara Rosin, Benito Almirante, Gianmaria Baldin, Antonio Vena, Emilio Bouza, Viviana de Egea, Carlo Tascini, Francesco Menichetti, Enrico Tagliaferri, Maurizio Sanguinetti, Alessio Mesini, Gabriele Sganga, Marina Busetti, Tomàs Pumarola, María Teresa Martín-Gómez, Simone Aranha Nouér, Teresa Peláez, Enzo Raise, Stefano Grandesso, Valerio Del Bono, Patrícia Esteves, Cecilia Trucchi, Assunta Sartor, Gennaro De Pascale, Brunella Posteraro, Claudio Scarparo, Patrícia Esteves,
Intraabdominal candidiasis (IAC) is the second most frequent form of invasive candidiasis, and is associated with high mortality rates. This study aims to identify current practices in initial antifungal treatment (IAT) in a real-world scenario and to define the predictors of the choice of echinocandins or azoles in IAC episodes. Secondary analysis was performed of a multinational retrospective cohort at 13 teaching hospitals in four countries (Italy, Greece, Spain and Brazil), over a 3-year period ( ...
Tópico(s): Parasitic Diseases Research and Treatment
2016 - Elsevier BV | Clinical Microbiology and Infection
Carlo Nucci, Raffaele Mancino, Alessio Martucci, Francesca Bolacchi, Guglielmo Manenti, Claudio Cedrone, Franco Culasso, Roberto Floris, L Cerulli, Francesco Garaci,
Objectives To correlate diffusion-tensor imaging (DTI) of the optic nerve with morphological indices obtained by scanning laser polarimetry (GDx-VCC); confocal scanning laser ophthalmoscopy (Heidelberg III retinal tomograph; HRT-III) and optical coherence tomography (Stratus OCT). Methods Thirty-six subjects (12 with no eye disease and 24 with perimetrically diagnosed glaucoma) were examined. One eye for each participant was studied with 3-Tesla DTI (with automatic generation of mean diffusivity (MD) and fractional ...
Tópico(s): Ophthalmology and Eye Disorders
2012 - BMJ | British Journal of Ophthalmology
... altresi i rniei collaboratori dr. Maria Pia Man- nucci e Sig. Claudio Friso. DESCRIZIONE DEI REPERTI Microplana giustii n. sp. ...
Tópico(s): Marine Ecology and Invasive Species
1976 - eScholarship Publishing, University of California | Biogeographia – The Journal of Integrative Biogeography
Raffaele Mancino, Elena Ciuffoletti, Alessio Martucci, Francesco Aiello, Claudio Cedrone, L Cerulli, Carlo Nucci,
In Brief Purpose: To evaluate the use of perfluoropropane gas (C3F8) versus silicone oil (SO) for retinal detachment secondary to macular hole in patients with high myopia and posterior staphyloma. Methods: In a retrospective study, 30 eyes of 30 patients underwent pars plana vitrectomy, and C3F8 (17 patients) or SO (13 patients) tamponade; internal limiting membrane peeling was performed successfully at the first surgery in 23 patients. High-density silicone oil tamponade was used for reoperations. ...
Tópico(s): Vascular Malformations Diagnosis and Treatment
2012 - Lippincott Williams & Wilkins | Retina
Claudio Cicinelli, Andrea Cossio, Francesco Nucci, Ottavio Ricchi, Cristian Tegami,
In this paper, we provide a description of the Italian Treasury Econometric Model (ITEM). We illustrate its general structure and model properties, especially with regard to the economy's response to changes in policy and in other dimensions of the economic environment. One of the key features of the model is the joint representation of the economy on both the demand and the supply sides. Since it is designed for the needs of a Treasury Department, its public finance section is developed in great ...
Tópico(s): Italy: Economic History and Contemporary Issues
2009 - Elsevier BV | Economic Modelling
Francesco Aiello, Federico Genzano Besso, Giulio Pocobelli, Gabriele Gallo Afflitto, Rossella Anna Maria Colabelli Gisoldi, Carlo Nucci, Diego Ponzin, Paola Bonci, G. Calabrò, Roberto Ceccuzzi, Massimiliano Corneli, G. Genitti, Claudio Giannarini, Raffaela Mistò, Augusto Pocobelli, Achille Tortori, Davide Venzano,
Abstract To investigate the impact of Coronavirus Disease-2019 lockdown on the Italian Eye Bank organization. In this national retrospective, multicentric, cohort study, data from the Italian Eye Bank during both the lockdown and the first month after the lockdown period were retrieved. We compared the Italian Eye Bank metrics with the same timeframe of 2019 and 2018. Data from 13 out of 13 (100%) Italian Eye Banks were included in the analysis. A statistically significant reduction in the number ...
Tópico(s): Corneal Surgery and Treatments
2021 - Springer Science+Business Media | Cell and Tissue Banking
Produção Nacional
Revisado por pares
Matteo Bassetti, Maddalena Peghin, Alessia Carnelutti, Elda Righi, Maria Merelli, Filippo Ansaldi, Cecilia Trucchi, Cristiano Alicino, Assunta Sartor, Pierluigi Toniutto, Joost Wauters, Wim Laleman, Carlo Tascini, Francesco Menichetti, Roberto Luzzati, Pierluigi Brugnaro, Alessio Mesini, Stefania Raviolo, Francesco Giuseppe De Rosa, Leonel Lagunes, Jordi Rello, George Dimοpoulos, Arnaldo Lopes Colombo, Márcio Nucci, Antonio Vena, Emilio Bouza, Patricia Muñóz, Mario Tumbarello, Raffaella Losito, Ignacio Martín‐Loeches, Claudio Viscoli,
The aim of the study was to describe the characteristics of cirrhotic patients with candidemia and intra-abdominal candidiasis (IAC) and to evaluate the risk factors associated with 30-day mortality.A multicenter multinational retrospective study including all consecutive episodes of candidemia and IAC in adult patients with liver cirrhosis in 14 European hospitals during the period 2011-2013 was performed.A total of 241 episodes (169 candidemia, 72 IAC) were included. Most Candida infections were ...
Tópico(s): Amoebic Infections and Treatments
2017 - Springer Science+Business Media | Intensive Care Medicine
Roberto dell’Omo, Mariaelena Filippelli, Gianni Virgili, Francesco Bandello, Giuseppe Querques, Paolo Lanzetta, Teresio Avitabile, Francesco Viola, Michele Reibaldi, Francesco Semeraro, Luciano Quaranta, Stanislao Rizzo, Edoardo Midena, Giuseppe Campagna, Ciro Costagliola, Paola Marolo, Carlo Enrico Traverso, Michele Iester, Carlo Alberto Cutolo, Claudio Azzolini, Simone Donati, Elias Premi, Paolo Nucci, Stela Vujosevic, Giovanni Staurenghi, Ferdinando Bottoni, F. Romano, Domenico Grosso, Enrico Borrelli, Riccardo Sacconi, Paolo Milella, Simone Ganci, Mario R. Romano, Gabriella Ricciardelli, Davide Allegrini, Marco Casaluci, Davide Romano, Giorgio Marchini, Francesca Chemello, Camilla Amantea, Rino Frisina, Elisabetta Pilotto, Raffaele Parrozzani, Daniele Veritti, Valentina Sarao, Daniele Tognetto, Massimo Busin, Francesco Parmeggiani, Katia De Nadai, Luca Furiosi, Rodolfo Mastropasqua, Bruno Battaglia, Matteo Gironi, Stefano Gandolfi, Enrico Luciani, Paolo Mora, Costantino Schiavi, Patrizia Bertaccini, Alessandro Finzi, Matilde Roda, Carlo Cagini, Marco Lupidi, Fabrizio Giansanti, Daniela Bacherini, Gianmarco Tosi, E. Benedetto, Marco De Nardi, Michele Figus, Chiara Posarelli, Cesare Mariotti, Vittorio Pirani, Michele Nicolai, Stefano Bonini, Marco Coassin, Antonio Di Zazzo, Maria Cristina Savastano, Alfonso Savastano, Gloria Gambini, Umberto De Vico, Leopoldo Spadea, Andrea Iannaccone, Carlo Nucci, Federico Ricci, Francesco Aiello, Gabriele Gallo Afflitto, Leonardo Mastropasqua, Giada D’Onofio, Federica Evangelista, Lorenza Brescia, Pasquale Napolitano, Paolo Polisena, Nicolina Gianfrancesco, Domenico Trivisonno, Francesco Petti, Francesca Simonelli, Settimio Rossi, Antonio Tartaglione, Nicola Rosa, Maddalena De Bernardo, Cristiana Iaculli, Anna V. Bux, Giulia Maggiore, Francesco Boscia, Giancarlo Sborgia, Maria Oliva Grassi, Vincenzo Scorcia, Giuseppe Giannaccare, Guglielmo Parisi, Salvatore Cillino, Francesco Alaimo, Pasquale Aragona, Alessandro Meduri, Antonio Pinna, Andrea Sollazzo, Enrico Peiretti, Emanuele Siotto Pintor,
To compare the number of eye surgical procedures performed in Italy in the 2 months following the beginning of lockdown (study period) because of COVID-19 epidemic with those performed in the two earlier months of the same year (intra-year control) and in the period of 2019 corresponding to the lockdown (inter-year control).Retrospective analysis of surgical procedures carried out at 39 Academic hospitals. A distinction was made between elective and urgent procedures. Intravitreal injections were also ...
Tópico(s): Traumatic Ocular and Foreign Body Injuries
2021 - SAGE Publishing | European Journal of Ophthalmology
Francesco Garaci, Francesca Bolacchi, Angelica Cerulli, Milena Melis, A. Spanò, Claudio Cedrone, Roberto Floris, Giovanni Simonetti, Carlo Nucci,
To evaluate, with high-field-strength diffusion-tensor (DT) magnetic resonance (MR) imaging, the axonal architecture of the optic nerves and optic radiations in patients with glaucoma and determine whether DT MR imaging-derived parameters correlate with disease severity.The study was approved by the institutional review board. All participants provided written informed consent. Sixteen patients with primary open-angle glaucoma were examined. Glaucoma severity was clinically assessed with use of a ...
Tópico(s): Ophthalmology and Eye Disorders
2009 - Radiological Society of North America | Radiology
Claudio Cedrone, Franco Culasso, Massimo Cesareo, Carlo Nucci, Stefano Di Palma, Raffaele Mancino, L Cerulli,
Purpose To study the incidence of blindness and low vision over a 7-year period. Design Population-based cohort study. Participants The survivors of the original cohort of 860 persons from Priverno, Italy, aged 45 to 69 years, were reexamined. Of the 760 eligible survivors, 619 (81.4%) had a 7-year follow-up visit. Methods Baseline and follow-up examinations included the collection of anamnestic and ophthalmologic data by the same observers using the same methods and classification criteria to minimize ...
Tópico(s): Retinal Diseases and Treatments
2003 - Elsevier BV | Ophthalmology
C.E. Traverso, JG Walt, Simon P. Kelly, A. H. Hommer, Alain M. Bron, P. Denis, J.–P. Nordmann, JP RENARD, Atilla Bayer, Franz Grehn, Norbert Pfeiffer, Claudio Cedrone, S. Gandolfi, N. Orzalesi, Carlo Nucci, Luca Rossetti, Augusto Azuara‐Blanco, Alessandro Bagnis, Roger A. Hitchings, John F. Salmon, G. Bricola, P. M. Buchholz, S. Kotak, Louis M. Katz, L. R. Siegartel, John Doyle,
Resource utilisation and direct costs associated with glaucoma progression in Europe are unknown. As population progressively ages, the economic impact of the disease will increase.From a total of 1655 consecutive cases, the records of 194 patients were selected and stratified by disease severity. Record selection was based on diagnoses of primary open angle glaucoma, glaucoma suspect, ocular hypertension, or normal tension glaucoma; 5 years minimum follow up were required. Glaucoma severity was ...
Tópico(s): Retinal Diseases and Treatments
2005 - BMJ | British Journal of Ophthalmology
Carlo Nucci, C Varesi, Alessio Martucci, Massimo Cesareo, Claudio Cedrone, Raffaele Mancino, L Cerulli,
Purpose To investigate the intraocular pressure (IOP) reduction with prostaglandin analogs (PGAs)–timolol fixed combinations versus the unfixed combination of the same PGAs and timolol 0.1% in gel-forming carbomer. Methods Patients with primary open-angle glaucoma (POAG) receiving for at least 4 weeks the fixed combinations of PGA-timolol, administered once a day in the evening (0.005% latanoprost with 0.5% timolol, 0.004% travoprost with 0.5% timolol, 0.03% bimatoprost with 0.5% timolol) were switched ...
Tópico(s): Ophthalmology and Eye Disorders
2013 - SAGE Publishing | European Journal of Ophthalmology
Produção Nacional
Revisado por pares
Rodrigo Álvaro Brandão Lopes‐Martins, Edson Antunes, Maria Luiza Vilela Oliva, Cláudio A.M. Sampaio, J.L. Burton, Gilberto De Nucci,
The roles of the tissue kallikrein‐kinin system and nitric oxide (NO) release in Phoneutria nigriventer venom‐induced relaxations of rabbit corpus cavernosum (RbCC) smooth muscle have been investigated by use of a bioassay cascade. Phoneutria nigriventer venom (10–30 μg), porcine pancreatic kallikrein (100 mu), rabbit urinary kallikrein (10 mu), bradykinin (BK, 0.3–3 nmol), acetylcholine (ACh, 0.3–30 nmol) and glyceryl trinitrate (GTN, 0.5–10 nmol) caused relaxations of the RbCC strips. Captopril (1 μ m ) ...
Tópico(s): Hormonal and reproductive studies
1994 - Wiley | British Journal of Pharmacology