John A. Professor Kanis, L. Joseph Melton, Claus Christiansen, C. Conrad Johnston, Nikolaï Khaltaev,
... Rochester, MinnesotaSearch for more papers by this authorClaus Christiansen, Claus Christiansen Center for Clinical and Basic Research (CCBR), ... Rochester, MinnesotaSearch for more papers by this authorClaus Christiansen, Claus Christiansen Center for Clinical and Basic Research (CCBR), Ballerup, ...
Tópico(s): Bone Metabolism and Diseases
1994 - Oxford University Press | Journal of Bone and Mineral Research
... AS A PROPHYLACTIC TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS Claus Christiansen, Claus Christiansen Department of Clinical Chemistry, Glostrup Hospital, University ... DenmarkSearch for more papers by this author Claus Christiansen, Claus Christiansen Department of Clinical Chemistry, Glostrup Hospital, University of ...
Tópico(s): Vitamin K Research Studies
1986 - Wiley | Acta Pharmacologica et Toxicologica
David Hosking, Clair Chilvers, Claus Christiansen, Pernille Ravn, Richard D. Wasnich, Philip D. Ross, Michael R. McClung, Ana Balske, Desmond Thompson, Marianne Daley, A.J.P. Yates,
Hosking, David; Chilvers, Clair E. D.; Christiansen, Claus; Ravn, Pernille; Wasnich, Richard; Ross, Philip; McClung, Michael; Balske, Ana; Thompson, Desmond; Daley, Marianne; Yates, A. John Author Information
Tópico(s): Bone and Joint Diseases
1998 - Lippincott Williams & Wilkins | Obstetrical & Gynecological Survey
Pierre D. Delmas, Nina H. Bjarnason, Bruce Mitlak, Anne-Catherine Ravoux, Aarti S. Shah, William J. Huster, Michael Draper, Claus Christiansen,
... Shah, Aarti S.; Huster, William J.; Draper, Michael; Christiansen, Claus Author Information
Tópico(s): Estrogen and related hormone effects
1998 - Lippincott Williams & Wilkins | Obstetrical & Gynecological Survey
G Jensen, Claus Christiansen, J Boesen, V. Hegedüs, Ib Transbøl,
JENSEN, GRETHE FINN M.D.; CHRISTIANSEN, CLAUS M.D.; BOESEN, JENS M.D.; HEGEDÜS, VIKTOR M.D.; TRANSBØL, IB M.D.Editor(s): MORRISSY, RAYMOND T. M.D. ...
Tópico(s): Bone health and treatments
1982 - Lippincott Williams & Wilkins | Clinical Orthopaedics and Related Research
Anders Gotfredsen, Orla Skibsted Als, Lone Tjellesen, Lisbeth Nilas, Jens Borg, Claus Christiansen,
... Als, Orla; Tjellesen, Lone; Nilas, Lisbeth; Borg, Jens; Christiansen, Claus Author Information
Tópico(s): Vitamin D Research Studies
1983 - Lippincott Williams & Wilkins | Journal of Computer Assisted Tomography
Liesbeth Vandenput, Helena Johansson, Eugène McCloskey, Enwu Liu, Marian Schini, Kristina Åkesson, Fred Anderson, Rafael Azagra, Cecilie Liv Bager, Charlotte Beaudart, Heike A. Bischoff‐Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A. Cauley, Jacqueline R. Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn Crandall, Steven R. Cummings, José António Pereira da Silva, Bess Dawson‐Hughes, Adolfo Díez‐Pérez, Alyssa B. Dufour, John A. Eisman, Petra J. M. Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus‐Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Guðnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish‐Shalom, Graeme Jones, Magnus K. Karlsson, Sundeep Khosla, Douglas P. Kiel, Woon‐Puay Koh, Fjorda Koromani, Mark A. Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Fiona E. McGuigan, Dan Mellström, Thomas Merlijn, Tuan V. Nguyen, Anna Nordström, Peter Nordström, Terence W O’Neill, Barbara Obermayer‐Pietsch, Claes Ohlsson, Eric Orwoll, Julie A. Pasco, Fernando Rivadeneira, Anne‐Marie Schott, Eric J. Shiroma, Kristín Siggeirsdóttir, Eleanor M. Simonsick, Elisabeth Sornay‐Rendu, Reijo Sund, Karin M. A. Swart, Paweł Szulc, Junko Tamaki, David Torgerson, Natasja M. van Schoor, Tjeerd van Staa, Joan Vila, Nicholas J. Wareham, Nicole C. Wright, Noriko Yoshimura, MCarola Zillikens, Marta Zwart, Nicholas C. Harvey, Mattias Lorentzon, William D. Leslie, John А. Kanis,
Tópico(s): Cerebral Palsy and Movement Disorders
2024 - Springer Science+Business Media | Osteoporosis International
Daniel J. Brotman, John P. Girod,
... PhD, Bagger Yu Z., , MD, Alexandersen Peter, , MD, Christiansen Claus, , MD, and Larsen Philip J., , MD, PhD26082003We thank ...
Tópico(s): Adipose Tissue and Metabolism
2003 - Lippincott Williams & Wilkins | Circulation
... PhD, Bagger Yu Z., , MD, Alexandersen Peter, , MD, Christiansen Claus, , MD, PhD, and for the Prospective Epidemiological Risk ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2003 - Lippincott Williams & Wilkins | Circulation
Henning Boje Andersen, Gunna Christiansen, Claus Christiansen,
The acidic proteins of six different mycoplasma serotypes causing bovine or caprine pleuro-pneumonia were compared by two-dimensional gel electrophoresis of extracts of 35S-labelled cells. The organisms investigated were Mycoplasma mycoides subsp. mycoides (PG1), M. mycoides subsp. mycoides (Y-goat), M. mycoides subsp. capri (PG3), M. capricolum (California kid), the unclassified bovine serogroup 7 of Leach (PG50) and the F38-like group (F38). The results suggested a close relationship between M. capricolum ...
Tópico(s): Bacteriophages and microbial interactions
1984 - Microbiology Society | Microbiology
Claus Gyrup, Michael Christiansen, Claus Oxvig,
Abstract Background: Maternal serum concentrations of pregnancy-associated plasma protein-A (PAPP-A, pappalysin-1, EC 3.4.24.79) are used to predict the occurrence of Down syndrome. In pregnancy, PAPP-A primarily circulates as a covalent 2:2 complex with the proform of eosinophil major basic protein (proMBP), which inhibits the proteolytic activity of PAPP-A. At term, however, ∼1% of PAPP-A exists as an active, uncomplexed dimer with proteolytic activity directed specifically toward insulin-like growth ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2007 - American Association for Clinical Chemistry | Clinical Chemistry
Christopher M. Burton, Pernille Kristensen, Rikke Lützhøft, Mette Rasmussen, Nils Milman, Jørn Carlsen, Claus Bohn Christiansen, Claus Andersen, Martin Iversen,
Cytomegalovirus (CMV) remains an important cause of morbidity and mortality in lung transplant recipients. We investigated the incidence of CMV infection in relation to CMV prophylaxis, and recipient-donor CMV serotype, in a cohort of 250 consecutive lung transplant recipients. All patients received 3 months CMV prophylaxis with acyclovir (n = 67) or gancyclovir (n = 183). Recipient-donor CMV serotype matching was performed in patients receiving acyclovir: R + /D+(n = 38), R + /D−(n = 10), R − /D+(n = 1), R − /D−(n = 16), ...
Tópico(s): Toxoplasma gondii Research Studies
2006 - Informa | Scandinavian Journal of Infectious Diseases
Jens Juel Christiansen, Claus Højbjerg Gravholt, Sanne Fisker, Niels Møller, Marianne Andersen, Birgit Svenstrup, Paul Bennett, Per Ivarsen, Jens Sandahl Christiansen, Jens Otto Lunde Jørgensen,
Objective : In female adrenal insufficiency, dehydroepiandrosterone (DHEA) secretion is impaired and circulating androgen levels are severely reduced. We wanted to analyse the acute effects of physiological DHEA substitution on substrate metabolism. Design : We studied nine females with adrenal insufficiency after 9 days of oral DHEA replacement (50 mg/day) in a double-blind, placebo-controlled crossover study. Methods : Whole body and regional substrate metabolism was assayed in the basal state and during ...
Tópico(s): Adipose Tissue and Metabolism
2005 - Oxford University Press | European Journal of Endocrinology
G. Sørensen, Morten Krogh Jensen, Pia Weikop, Ditte Dencker, Søren H. Christiansen, Claus J. Løland, Cecilie Hee Bengtsen, Jørgen Holm Petersen, Anders Fink‐Jensen, Gitta Wörtwein, David P.D. Woldbye,
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2012 - Springer Science+Business Media | Psychopharmacology
Lars Christian Gormsen, Christian Høst, Britta Eilersen Hjerrild, Steen B. Pedersen, Søren Nielsen, Jens Sandahl Christiansen, Claus Højbjerg Gravholt,
Context Estradiol (E 2 ) promotes and maintains the female phenotype characterized by subcutaneous fat accumulation. There is evidence to suggest that this effect is due to increased anti-lipolytic α2A-adrenergic receptors, but whether this requires long-term exposure to E 2 or is an immediate effect is not clear. Objective To study acute effects of a single dose (4 mg) of 17β-E 2 on regional and systemic lipolysis. Methods Sixteen postmenopausal women (age, 59±5 years; weight, 67±10 kg; and BMI, 24. ...
Tópico(s): Estrogen and related hormone effects
2012 - Oxford University Press | European Journal of Endocrinology
Kirstine Stochholm, Svend Juul, Jens Sandahl Christiansen, Claus Højbjerg Gravholt,
Objective Childhood onset GH deficiency (CO-GHD) is associated with increased morbidity and mortality; however, the patients' socioeconomic profile as adults is not fully known. Design Register study using Danish nationwide registries. Two hundred and sixty GHD males and 156 GHD females and 25 358 male and 15 110 female controls were included. Methods Information was obtained concerning cohabitation, parenthood, education, income, retirement, convictions, and death. Income was analyzed using conditional ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2012 - Oxford University Press | European Journal of Endocrinology
Søren Kløverpris, Louise L. Skov, Simon Glerup, Kasper Pihl, Michael Christiansen, Claus Oxvig,
The plasma concentration of the placentally derived proMBP (proform of eosinophil major basic protein) increases in pregnancy, and three different complexes containing proMBP have been isolated from pregnancy plasma and serum: a 2:2 complex with the metalloproteinase, PAPP-A (pregnancy-associated plasma protein-A), a 2:2 complex with AGT (angiotensinogen) and a 2:2:2 complex with AGT and complement C3dg. In the present study we show that during human pregnancy, all of the circulating proMBP exists ...
Tópico(s): Pregnancy and preeclampsia studies
2012 - Portland Press | Biochemical Journal
Chris Jensen, Ole Kudsk Jensen, David Høyrup Christiansen, Claus Vinther Nielsen,
In Brief Study Design. Randomized clinical trial comparing two interventions in employees sick-listed 3 to 16 weeks because of low back pain (LBP). Objective. To compare 1-year return to work (RTW), pain, disability and physical and mental health dimensions in subjects offered a hospital-based multidisciplinary intervention or a brief intervention. Summary of Background Data. Previous studies in sick-listed employees with LBP have indicated efficacy of both brief and more comprehensive multidisciplinary ...
Tópico(s): Occupational health in dentistry
2011 - Lippincott Williams & Wilkins | Spine
Eric Bentzen, John K. Christiansen, Claus J. Varnes,
Purpose Managers' attention is a scarce resource in complex innovation settings. Prior research on the factors to which managers pay attention is mostly based on surveys. The present study aims to address the need for knowledge about the behavior of decision makers based on observations from portfolio meetings. The study seeks to investigate how managers allocate their attention and the role of different factors for their attention. Observations also make it possible to compare prior research and ...
Tópico(s): Construction Project Management and Performance
2011 - Emerald Publishing Limited | Management Decision
Kristian H. Mortensen, Britta Hjerrild, Kirstine Stochholm, N.H. Andersen, Keld E. Sørensen, Erik Lundorf, Arne Hørlyck, Erik Morre Pedersen, Jens Sandahl Christiansen, Claus Højbjerg Gravholt,
The risk of aortic dissection is 100-fold increased in Turner syndrome (TS). Unfortunately, risk stratification is inadequate due to a lack of insight into the natural course of the syndrome-associated aortopathy. Therefore, this study aimed to prospectively assess aortic dimensions in TS. Eighty adult TS patients were examined twice with a mean follow-up of 2.4 ± 0.4 years, and 67 healthy age and gender-matched controls were examined once. Aortic dimensions were measured at nine predefined positions ...
Tópico(s): Cardiac Valve Diseases and Treatments
2011 - BioMed Central | Journal of Cardiovascular Magnetic Resonance
Kristian H. Mortensen, Britta Eilersen Hjerrild, N.H. Andersen, Keld E. Sørensen, Arne Hørlyck, Erik Morre Pedersen, Erik Lundorf, Jens Sandahl Christiansen, Claus Højbjerg Gravholt,
Abstract Background Ectatic aortopathy and arterial abnormalities cause excess morbidity and mortality in Turner syndrome, where a state of vasculopathy seemingly extends into the major head and neck branch arteries. Objective We investigated the prevalence of abnormalities of the major intrathoracic arteries, their interaction with arterial dimensions, and their association with karyotype. Design Magnetic resonance imaging scans determined the arterial abnormalities as well as head and neck branch ...
Tópico(s): Cardiac Valve Diseases and Treatments
2010 - Cambridge University Press | Cardiology in the Young
John K. Christiansen, Claus J. Varnes, Marta Gasparin, Diana Storm‐Nielsen, Erik Johnsen Vinther,
Product value and life are usually expected to follow the product life cycle (PLC), wherein products are expected to move from an investment toward a profitable mature peak that ends when the product is phased out. This study illustrates the sales volume of Arne Jacobsen's Egg chair over a 50‐year period, shifting from low to high volume to extremely low to high again. This study introduces a theoretical perspective in which value creation is described as a process of valuing, in which an assumption ...
Tópico(s): Information Systems Theories and Implementation
2010 - Wiley | Journal of Product Innovation Management
Christian Høst, Anders Bojesen, Jan Frystyk, Allan Flyvbjerg, Jens Sandahl Christiansen, Claus Højbjerg Gravholt,
Sex hormones have been shown to influence levels of adiponectin. Furthermore, testosterone has been shown to alter the subform distribution of adiponectin, whereas the effects of oestradiol are equivocal. We investigated the impact of sex hormone replacement therapy (HRT) on circulating adiponectin and its subforms, fasting lipids and measures of insulin sensitivity in Turner syndrome (TS) and Klinefelter syndrome (KS) respectively.We compared eight young TS patients on and off 2 months of HRT vs. ...
Tópico(s): Hormonal and reproductive studies
2010 - Wiley | European Journal of Clinical Investigation
Michael Christiansen, Claus Oxvig, Jill M. Wagner, Qiuping Qin, Tri Huu Nguyen, Michael T. Overgaard, Severin Olesen Larsen, Lars Sottrup‐Jensen, Gerald J. Gleich, Bent Nørgaard‐Pedersen,
The proform of eosinophil major basic protein (proMBP), the most abundant protein in the eosinophil specific granule, is synthesized by the placenta and secreted into the maternal circulation, where it is found complex-bound to pregnancy-associated plasma protein-A (PAPP-A) and other proteins. We examined the potential of proMBP as a maternal serum marker for fetal Down syndrome (DS) by determining its maternal serum concentration (MSpMBP) in 25 Down syndrome (DS) pregnancies and 152 control pregnancies ...
Tópico(s): Parvovirus B19 Infection Studies
1999 - Wiley | Prenatal Diagnosis
Qiuping Qin, Michael Christiansen, Claus Oxvig, Kim Pettersson, Lars Sottrup‐Jensen, Claus Koch, Bent Nørgaard‐Pedersen,
Four double-monoclonal time-resolved immunofluorometric assays (TrIFMAs) have been developed for the specific determination of pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/ proMBP) complex in first-trimester maternal serum samples. The assays have a functional sensitivity of < 4 mIU/L and a working range from 4 to 1000 mIU/L. These 4 assays, together with a polyclonal sandwich TrIFMA, were compared for their ability to discriminate between normal pregnancies (n = 149) ...
Tópico(s): Gestational Trophoblastic Disease Studies
1997 - American Association for Clinical Chemistry | Clinical Chemistry
Douglas V.N.P. Oliveira, Tine Henrichsen Schnack, Tim Svenstrup Poulsen, Anne Pernille Christiansen, Claus Høgdall, Estrid Høgdall,
Ovarian clear cell carcinoma (OCCC) is characterized by dismal prognosis, partially due to its low sensitivity to standard chemotherapy regimen. It is also well-known for presenting unique molecular features in comparison to other epithelial ovarian cancer subtypes. Here, we aim to identify potential subgroups of patients in order to (1) determine their molecular features and (2) characterize their mutational signature. Furthermore, we sought to perform the investigation based on a potentially clinically ...
Tópico(s): Cancer Genomics and Diagnostics
2021 - Multidisciplinary Digital Publishing Institute | Cancers
Sofie Bliddal, Ulla Feldt‐Rasmussen, Åse Krogh Rasmussen, Astrid Marie Kolte, Linda Hilsted, Ole Bjarne Christiansen, Claus Henrik Nielsen, Henriette Svarre Nielsen,
Background: Thyroid autoimmunity has been associated with pregnancy loss. Suggested mechanisms include thyroid function aberrations or an underlying breach of immunotolerance. We hypothesized that thyroid autoimmunity is a marker of the latter in women with recurrent pregnancy loss. This study investigated thyroid peroxidase antibody (TPOAb) status as a predictor of live birth in women with unexplained recurrent pregnancy loss. Methods: Cohort study of 825 consecutive women with recurrent pregnancy ...
Tópico(s): Pregnancy and preeclampsia studies
2019 - Mary Ann Liebert, Inc. | Thyroid
Stephanie Kroeze, Christoph Henkenberens, Nina-Sophie Schmidt-Hegemann, Marco M. E. Vogel, Simon Kirste, J. Becker, Irene A. Burger, Thorsten Derlin, Peter Bartenstein, Matthias Eiber, Michael Mix, Christian la Fougère, Hans Christiansen, Claus Belka, Stephanie E. Combs, Anca‐Ligia Grosu, Arndt‐Christian Müller, Matthias Gückenberger,
Background Approximately 40–70% of biochemically recurrent prostate cancer (PCa) is oligorecurrent after prostate-specific membrane antigen (PSMA) positron emission tomography (PET) staging. Metastasis-directed radiotherapy (MDT) of PSMA-positive oligorecurrence is now frequently used, but the role of concurrent androgen deprivation therapy (ADT) remains unclear. Objective To determine the effect of concurrent ADT with PSMA PET–directed MDT on biochemical progression-free survival (bRFS). Design, setting, ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2019 - Elsevier BV | European Urology Focus
Line Thorndal Moll, Ole Kudsk Jensen, Berit Schiøttz‐Christensen, Christina Malmose Stapelfeldt, David Høyrup Christiansen, Claus Vinther Nielsen, Merete Labriola,
Purpose The aim of this study was to evaluate the effect of a multidisciplinary intervention (MDI) compared to a brief intervention (BI) with respect to return to work (RTW), pain and disability in workers on sick leave because of neck or shoulder pain. Methods 168 study participants with sickness absence for 4–16 weeks due to neck or shoulder pain were enrolled in a hospital-based clinical study and randomized to either MDI or BI. The primary outcome was RTW obtained by a national registry on public ...
Tópico(s): Occupational Health and Safety Research
2017 - Springer Science+Business Media | Journal of Occupational Rehabilitation
Karynsa Cetin, Christian Fynbo Christiansen, Claus Sværke, Jacob Jacobsen, Henrik Toft Sørensen,
Objectives Since population-based data on prognostic factors affecting survival in patients with breast cancer with bone metastasis (BM) are currently limited, we conducted this nationwide retrospective cohort study to examine the prognostic role of disease stage at breast cancer diagnosis and length of BM-free interval (BMFI). Setting Denmark. Participants 2427 women with a breast cancer diagnosis between 1997 and 2011 in the Danish Cancer Registry and a concurrent or subsequent BM diagnosis in the ...
Tópico(s): Management of metastatic bone disease
2015 - BMJ | BMJ Open