Mamou Diallo, Servé W. M. Kengen, Ana M. López‐Contreras,
... compelling organisms for biotechnological production processes; while acetogenic clostridia can fix C1-compounds to produce acetate and ethanol, solventogenic clostridia can utilize a wide range of carbon sources ... to result in economically viable processes. Engineering solventogenic clostridia by impairing sporulation is one of the investigated ... has been mainly studied in bacilli and pathogenic clostridia, and our knowledge of sporulation in solvent-producing or acetogenic clostridia is limited. Still, sporulation is an integral part ...
Tópico(s): Porphyrin Metabolism and Disorders
2021 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Silje F. Jørgensen, Kristian Holm, Magnhild E. Macpherson, Christopher Storm-Larsen, Martin Kummen, Børre Fevang, Pål Aukrust, Johannes R. Hov,
... Coriobacteriaceae.Adlercreutzia11135911111Cyanobacteria.Melainabacteria.Gastranaerophilales.gut metagenome.gut metagenome111116311111Firmicutes.Clostridia.Clostridiales.Lachnospiraceae.[Eubacterium] fissicatena group∗The most prevalent ... patients with SIgAD compared with healthy controls.1111117121589Firmicutes.Clostridia.Clostridiales.Lachnospiraceae.Lachnospiraceae AC2044 group11138311111Firmicutes.Clostridia.Clostridiales.Lachnospiraceae.uncultured bacterium†The most prevalent taxa ( ... healthy controls compared with patients with SIgAD.112717111111Firmicutes.Clostridia.Clostridiales.Peptococcaceae.Peptococcus111178811111Firmicutes.Clostridia.Clostridiales.Ruminococcaceae.Candidatus Soleaferrea11112011111Firmicutes. ...
Tópico(s): Pediatric health and respiratory diseases
2019 - Elsevier BV | Journal of Allergy and Clinical Immunology
... 319Crossref PubMed Scopus (133) Google Scholar revealed that Clostridia added to mouse infant gut microbiota are sufficient ... 319Crossref PubMed Scopus (133) Google Scholar revealed that Clostridia added to mouse infant gut microbiota are sufficient ... 315-319Crossref PubMed Scopus (133) Google Scholar identified Clostridia as the essential class of bacteria that protects ... Google Scholar demonstrated that two independent consortia of Clostridia, when given to germ-free mice colonized with ... 12 species did not reduce pathogen burden. Therefore, Clostridia, but not Bacteroides, are essential for providing colonization ...
Tópico(s): Infant Health and Development
2017 - Cell Press | Cell Host & Microbe
Jason R. Barash, Jennifer K. Hsia, Stephen S. Arnon,
... in 2006-2007 were cultured anaerobically to isolate clostridia. All isolated clostridia were identified to the species level and enumerated ... 10 other soil-dwelling clostridial species. No neurotoxigenic clostridia were isolated. The most probable number of clostridial ... The isolation of C sporogenes and potentially pathogenic clostridia from U.S.-manufactured PIF suggests that neurotoxigenic ... in 2006-2007 were cultured anaerobically to isolate clostridia. All isolated clostridia were identified to the species ...
Tópico(s): Diphtheria, Corynebacterium, and Tetanus
2009 - Elsevier BV | The Journal of Pediatrics
Asami Saito, Makoto Kawahara, Seishi Ikeda, Masato Ishimine, Shoichiro Akao, Kiwamu Minamisawa,
Endophytic clostridia present on various plants as obligate anaerobes were surveyed by terminal restriction fragment length polymorphism (TRFLP) analysis specific to the clostridial 16S rRNA gene. Endophytic clostridia were detected in 10 plant types: sugarcane, cultivated ... fescue, and three mangrove species. Phylogenetically, cluster XIVa clostridia were detected more frequently than cluster I clostridia in aerial parts. Isolation of clostridia from surface-sterilized sugarcane stem validated the TRFLP ...
Tópico(s): Microbial Community Ecology and Physiology
2008 - Japanese Society Of Microbial Ecology | Microbes and Environments
D.M. Broda, Robert G. Bell, J.A. Boerema, D. R. Musgrave,
... identify the abattoir source(s) of culturable psychrophilic clostridia causing 'blown pack' spoilage of vacuum-packed chilled meats.Psychrophilic and psychrotolerant clostridia were isolated from hides, faeces and tonsils of ... transcribed spacer (ITS) analysis. PCR-RFLP group I clostridia were found to have restriction patterns indistinguishable from ... with vegetative cells of PCR-RFLP group I clostridia was first evident after 14 days at 2 degrees C. The prevalence of these clostridia was similar in hide and faecal samples from ...
Tópico(s): Gut microbiota and health
2002 - Oxford University Press | Journal of Applied Microbiology
... to isolate Bacteroides melaninogenicus from the gingival crevice, clostridia were observed in many of the primary cultures. ... normal gingival crevice, periodontal pockets and carious teeth. Clostridia were isolated from all three areas. The incidence ... interpreted as indicating that the infected environment inhibits clostridia. En cherchant à isoler Bacteroides melanogenicus du sillon gingivodentaire, des clostridia ont été observés dans un certain nombre de ... et des dents cariées a été entreprise. Des clostridia ont été isolés dans ces trois régions. Leur ...
Tópico(s): Bacterial Identification and Susceptibility Testing
1970 - Elsevier BV | Archives of Oral Biology
J.F. Elam, Richard L. Jacobs, Jason W Fowler, J.R. Couch,
... feeding of penicillin stimulated growth and decreased the Clostridia count per gram of feces in birds maintained ... Penicillin failed to stimulate growth or decrease the Clostridia count in birds maintained in clean quarters where the Clostridia population was low. 3. The feeding of fecal Clostridia decreased the growth rate of birds reared in ... penicillin to the diet. The feeding of fecal Clostridia to birds reared in old quarters where the Clostridia population was high failed to depress growth. 5. ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
1954 - SAGE Publishing | Experimental Biology and Medicine
Zhiqiang Wen, Qi Li, Jinle Liu, Mingjie Jin, Sheng Yang,
... gasoline substitute, that is commonly produced by solventogenic Clostridia. The main cost of cellulosic butanol fermentation is ... that are required to saccharify lignocellulose, since solventogenic Clostridia cannot efficiently secrete cellulases. However, cellulolytic Clostridia can natively degrade lignocellulose and produce ethanol, acetate, butyrate and even butanol. Therefore, cellulolytic Clostridia offer an alternative to develop consolidated bioprocessing ( CBP ), ... on CBP advances for butanol production of cellulolytic Clostridia and various synthetic biotechnologies that drive these advances. ...
Tópico(s): Enzyme Catalysis and Immobilization
2019 - Wiley | Microbial Biotechnology
Cong Ren, Zhiqiang Wen, Yan Xu, Weihong Jiang, Yang Gu,
Solventogenic clostridia are native producers of ethanol and many higher alcohols employing a broad range of cheap renewable substrates, ... gases (CO and CO2). These characteristics enable solventogenic clostridia to act as flexible microbial platforms for the ... tools in recent years, the intrinsic intractability of clostridia has been largely overcome, thus, engineering clostridia for production of chemicals and fuels has attracted ... in the production of alcohols based on solventogenic clostridia. Saccharolytic, cellulolytic and gas-fermenting clostridia are discussed, ...
Tópico(s): Biofuel production and bioconversion
2016 - Elsevier BV | Current Opinion in Chemical Biology
María del Mar Gamboa, Evelyn Rodríguez, Pablo Agustín Vargas,
... among the most frequent bacteria. The diversity of clostridia in Costa Rican soils and its possible association ... the South Pacific. The pH and the mesophilic clostridia species were determined for each sample. For bacterial ... were used. A total of 1945 strains of clostridia were isolated, 98% were identified and corresponded to ... species. Except for C. chauvoei, all described toxigenic clostridia species were isolated; C. sordellii (42%) and C. ... type of soil and any species, showing that clostridia had a high adaptation capability to grow in ...
Tópico(s): Genomics and Phylogenetic Studies
2005 - Elsevier BV | Anaerobe
Laura Calvo‐Barreiro, Herena Eixarch, Thais Cornejo, Carme Costa, Mireia Castillo, Leyre Mestre, Carmen Guaza, M. Carmen Martínez‐Cuesta, Takeshi Tanoue, Kenya Honda, Juan José González‐López, Xavier Montalbán, Carmen Espejo,
... gut dysbiosis. Among these, a significant decrease of Clostridia cluster IV and XIVa has been reported. In ... previously selected mixture of human gut-derived 17 Clostridia strains, which belong to Clostridia clusters IV, XIVa, and XVIII, on the clinical ... and lower immune responses in the CNS. Since Clostridia-treated mice were found to present higher levels ... Thus, this smaller therapeutic effect highlighted that the Clostridia-induced clinical effect was not exclusively related to ... alone. Although it is still unknown if these Clostridia strains will have the same effect on MS ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2021 - Springer Science+Business Media | Neurotherapeutics
Charles H. D. Williamson, Jason W. Sahl, Theresa J. Smith, Gary Xie, Brian Foley, Leonard A. Smith, Rafael Fernández, Miia Lindström, Hannu Korkeala, Paul Keim, Jeffrey T. Foster, Karen K. Hill,
... which are produced by six species/Groups of Clostridia, but the genetic background of the bacteria remains ... botulinum neurotoxin. Comparative genomic analyses of over 170 Clostridia genomes, including our draft genome assemblies for 59 newly sequenced Clostridia strains from six continents and publicly available genomic ... F as well as bivalent strains. BoNT-producing Clostridia and closely related Clostridia species were delineated with a variety of methods ... study of these bacteria. Comparative genomic analyses of Clostridia species illustrate the diversity of botulinum-neurotoxin-producing ...
Tópico(s): Diphtheria, Corynebacterium, and Tetanus
2016 - BioMed Central | BMC Genomics
Šárka Ročková, V. Rada, Petr Maršík, Eva Vlková, Věra Bunešová, Jan Sklenář, Igor Šplı́chal,
... bifidobacteria. However, infants born by caesarean section possess clostridia as a dominant intestinal bacterial group. The aim ... present study was to determine whether bifidobacteria and clostridia are able to grow on human milk oligosaccharides ( ... CM) and human milk (HM). Both bifidobacteria and clostridia grew on lactose and in CM. Bifidobacteria grew ... In contrast, 3 out of 5 strains of clostridia were not able to grow in HM. No ... to lysozyme, 4 out of 5 strains of clostridia were lysozyme-susceptible. It seems that HMOs together ...
Tópico(s): Breastfeeding Practices and Influences
2011 - Elsevier BV | Anaerobe
Yoshika Momose, Akiko Maruyama, Teruko Iwasaki, Yukiko Miyamoto, K. Itoh,
To determine phylogenetic groups of clostridia inhabiting the mouse intestine that are essential for normalization of germfree (GF) mice.Using both the culture method and cloning, clostridia inhabiting the mouse intestine were isolated, and phylogenetic ... determined to be identical to previously known identified clostridia. Although the taxonomy of mouse intestinal clostridia was complex, many of them belonged to Clostridium ... mice administered chloroform-treated CV mouse faeces. The clostridia that belonged to cluster XIVa were most often ...
Tópico(s): Probiotics and Fermented Foods
2009 - Oxford University Press | Journal of Applied Microbiology

Ernesto Tabacco, Serenella Piano, Laura Cavallarin, Thiago Fernandes Bernardes, G. Borreani,
... plantarum (LP) and Lactobacillus buchneri (LB) on the clostridia spore formation during aerobic deterioration has been studied. ... during which pH, temperature, nitrate, yeast, mould and clostridia spores were measured. Compared to the C and ... LB silages, resulting in an increased aerobic stability. Clostridia spores, determined by most probable number (MPN) procedure, ... g(-1) in C and LP sorghum silages.Clostridia spore count only slightly increased in the LB ... period of air exposure.The data indicated that clostridia spore outgrowth can take place during silo feedout ...
Tópico(s): Animal Nutrition and Physiology
2009 - Oxford University Press | Journal of Applied Microbiology
D.M. Broda, J.A. Boerema, Robert G. Bell,
... without isolation, and specifically detects the presence of clostridia which cause 'blown pack' spoilage of vacuum-packed ... internal transcribed spacer fragments of 'blown pack' causing clostridia in meat. The specificity of the developed procedures ... from close phylogenetic neighbours of 'blown pack' causing clostridia, food clostridia and common meat spoilage microorganisms. The sensitivity of ... the expected size with DNA templates from target clostridia, but failed to yield PCR products with DNAs ... used for rapid detection of 'blown pack' causing clostridia in commercial blown packs, or following low temperature ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2003 - Oxford University Press | Journal of Applied Microbiology
Yoshinori Umesaki, Hiromi Setoyama, Satoshi Matsumoto, Akemi Imaoka, Kikuji Itoh,
... of indigenous microbe, segmented filamentous bacteria (SFB) and clostridia, whose habitats are the small and large intestines, ... three kinds of gnotobiotic mice contaminated with SFB, clostridia, and both SFB and clostridia, respectively, in comparison with germfree (GF) or conventionalized ( ... SFB-mice. On association with both SFB and clostridia, the numbers and phenotypes of IEL in the ... Cvd mice on contamination with both SFB and clostridia. The number of immunoglobulin A (IgA)-producing cells ... that in GF mice. Taken together, SFB and clostridia promoted the development of both IEL and IgA- ...
Tópico(s): Gastrointestinal motility and disorders
1999 - American Society for Microbiology | Infection and Immunity
... on Bacterial Spores: Paper XIV). Spore Properties of Clostridia Occurring in Cheese J.-L. Bergère, J.-L. ... J. gen. Microbiol. 37, 41. Gibson, T. (1965). Clostridia in silage. J. appl. Bact. 28, 56. Goudkov, A. V. & Sharpe, M. E. (1965). Clostridia in dairying. J. appl. Bact. 28, 63. Gould, ... T. A. & Roberts, T. A. (1968). Inhibition of clostridia by nitrite. J. Fd Technol. 3, 91. Perkins, W. E. (1965). Production of clostridia spores. J. appl. Bact. 28, 1. Poole, G. & ... R. O. & Baillie, A. (1967). Fine structure of clostridia with special reference to the location of antigens ...
Tópico(s): Biochemical and Molecular Research
1970 - Wiley | Journal of Applied Bacteriology
D.P. Sartory, A.M. Pritchard, P. Holmes,
The enumeration of sulphite-reducing Clostridia from water upon egg yolk-free tryptose-sulphite-cycloserine agar (TSC) was evaluated against the standard UK method of enumeration upon ... sewage effluent, the recoveries of presumptive sulphite-reducing Clostridia were significantly higher on TSC than on MCA ( ... samples where the system integrity had been breached. Clostridia were isolated from 26 of the 224 groundwater ... isolates from TSC, 92.9% were confirmed as Clostridia, whilst only 56.5% of 23 isolates from ...
Tópico(s): Bacterial Identification and Susceptibility Testing
1993 - Pergamon Press | Water Science & Technology
Qingzhuo Wang, Naief H. Al Makishah, Qi Li, Yanan Li, Wenzheng Liu, Xiao‐Man Sun, Zhiqiang Wen, Sheng Yang,
... esters in non-natural but more potential hosts. Clostridia are a group of important industrial microorganisms since ... which are precursors for ester production. Besides, some Clostridia could utilize lignocellulosic biomass, industrial off-gas, or ... branched or straight-chain alcohols and acids. Therefore, Clostridia offer great potential to be engineered to produce ... the review, the efforts to produce esters from Clostridia via in vitro lipase-mediated catalysis and in ... comprehensively revisited. Besides, the advantageous characteristics of several Clostridia and clostridial consortia for bio-ester production and ...
Tópico(s): Enzyme Catalysis and Immobilization
2021 - Frontiers Media | Frontiers in Bioengineering and Biotechnology
Weimin Gao, Arokiasamy J. Francis,
... is uranium reduction under fermentation condition common among clostridia species, but also the strains differed in the ... in uranium(VI) and iron(III) reduction by clostridia demonstrated. When hydrogen was provided as the headspace ... occurred in the presence of whole cells of clostridia. This is in contrast to that of nitrogen as the headspace gas. Without clostridia cells, hydrogen alone could not result in uranium( ... in the medium could compromise uranium reduction by clostridia. In the end, a comprehensive model was proposed ...
Tópico(s): Radioactive element chemistry and processing
2013 - Hindawi Publishing Corporation | ISRN Biotechnology
Julia Martín-Díaz, Maria Ruiz-Hernando, Sergi Astals, F. Lucena,
The capability of clostridia spores to act as pathogen indicators in sewage sludge treatment was investigated. Sulfite-reducing clostridia and E. coli levels were monitored during waste ... pre-treatments followed by anaerobic digestion provoked reproducible clostridia increases. Specifically, up to 2.7log10 after 35. ... floc dissipation, the most plausible explanation for these clostridia increases is re-growth. These results question the suitability of clostridia spores as indicators of sludge treatment and other ...
Tópico(s): Fecal contamination and water quality
2016 - Elsevier BV | Bioresource Technology
Claire Morvan, Filipe Folgosa, Nicolas Kint, Miguel Teixeira, Isabelle Martin‐Verstraete,
Summary Clostridia comprise bacteria of environmental, biotechnological and medical interest and many commensals of the gut microbiota. Because of ... anaerobic lifestyle, oxygen is a major stress for Clostridia. However, recent data showed that these bacteria can ... and consume O 2 . Upon O 2 exposure, Clostridia redirect their central metabolism onto pathways less O ... 2 ‐reductase activities are usually encoded in other Clostridia. These two classes of enzymes play indeed a ... induced responses have been described so far in Clostridia. PerR acts as a key regulator of the ...
Tópico(s): Gut microbiota and health
2021 - Wiley | Environmental Microbiology
Shiliang Fan, Haidong Li, Rui Zhao,
... B. sinensis declined distinctly under the hypoxic condition. Clostridia was the main component serving as a module ... the shared operational taxonomic units (OTUs) belonged to Clostridia. These results suggested that Clostridia both occupied an important position in the two ... B. sinensis gut microbiota, however the niche of Clostridia was notably altered based on its interactions with ... species under the hypoxic condition. The interactions between Clostridia and other OTUs in the Y group network ... a hypoxic condition could affect the function of Clostridia in the network. The homeostasis of the B. ...
Tópico(s): Epigenetics and DNA Methylation
2020 - Elsevier BV | Aquaculture
Charles H. D. Williamson, Adam J. Vazquez, Karen K. Hill, Theresa J. Smith, Roxanne Nottingham, Nathan E. Stone, Colin J. Sobek, Jill Cocking, Rafael Fernández, Patricia Ascensión Bermejo Caballero, Owen P. Leiser, Paul Keim, Jason W. Sahl,
... paralysis known as botulism. While multiple species of clostridia produce BoNTs, the majority of human botulism cases ... which provide valuable information for characterizing BoNT-producing clostridia. The PCR assays are rapid, inexpensive tests that ... assign isolates to species/subgroups and to detect clostridia with botulinum neurotoxin gene ( bont ) clusters. IMPORTANCE Diverse clostridia produce the botulinum neurotoxin, one of the most ... a multiplex PCR assay was developed to differentiate clostridia that are most commonly isolated in connection with ...
Tópico(s): Diphtheria, Corynebacterium, and Tetanus
2017 - American Society for Microbiology | Applied and Environmental Microbiology
... whereby antibiotic-mediated depletion of anaerobes (e.g., Clostridia) and associated decreases in butyrate result in increased ... whereby antibiotic-mediated depletion of anaerobes (e.g., Clostridia) and associated decreases in butyrate result in increased ... that mice depleted of major anaerobic microorganisms (especially Clostridia) generate a more aerobic environment, which then allows ... Scholar). To examine whether S. Typhimurium might deplete Clostridia in the context of a natural course of ... this role by reducing the overall abundance of Clostridia. This phenotype was, at least in part, reversed ...
Tópico(s): Indoor Air Quality and Microbial Exposure
2016 - Cell Press | Cell Host & Microbe
Valarie McMurtry, Raegan W. Gupta, Lynn Tran, Eugene Blanchard, Duna Penn, Christopher M. Taylor, Michael J. Ferris,
... diversity and the relative abundance of Actinobacteria and Clostridia were significantly lower in NEC specimens compared to controls. The absence of Clostridia was significantly associated with NEC. Microbial diversity and Clostridia abundance and prevalence decreased with increasing severity of ... The low bacterial diversity, and the lack of Clostridia in lethal specimens, could indicate that the presence ... well as the presence of taxa such as Clostridia may play a role in attenuating inflammation leading ...
Tópico(s): Pediatric Hepatobiliary Diseases and Treatments
2015 - BioMed Central | Microbiome
Laurent Ferraris, Marie José Butel, Florence Campeotto, M Vodovar, Jean‐Christophe Rozé, Julio Aires,
... in PN are scarce. Few studies have reported clostridia colonization in PN whereas Bacteroides and bifidobacteria have ... intensive care units (NICUs), 79% were colonized by clostridia. Clostridium sp. colonization, with a high diversity of ... NICU (p = 0.048).This study shows that clostridia are part of the PN gut microbiota. It ... the first time information on the status of clostridia antimicrobial susceptibility in PN showing that strains were ... in NICUs. The main perinatal determinant influencing PN clostridia colonization appears to be the NICU environment.
Tópico(s): Intestinal Malrotation and Obstruction Disorders
2012 - Public Library of Science | PLoS ONE