Joseph M. Corey, Eva L. Feldman,
Extracellular matrix (ECM) proteins and cell-cell adhesion molecules (CAM) play important roles in neuronal development and differentiation. In the investigation of these roles, patterned substrates have proven to be a notably useful tool. Photolithographic and microprinting techniques can be used to make patterns of ECMs, CAMs, amino acids, and organofunctional groups for culturing neurons and other cell types. Experiments performed using these substrates have provided unique insights into the roles ...
Tópico(s): Neuroscience and Neural Engineering
2003 - Elsevier BV | Experimental Neurology
Galan Moody, Corey McDonald, A. Feldman, Todd E. Harvey, Richard P. Mirin, Kevin L. Silverman,
Minimizing decoherence due to coupling of a quantum system to its fluctuating environment is at the forefront of quantum information science and photonics research. Nature sets the ultimate limit, however, given by the strength of the system's coupling to the electromagnetic field. Here, we establish the ability to electronically control this coupling and $\textit{enhance}$ the coherence time of a quantum dot excitonic state. Coherence control is demonstrated on the positively charged exciton transition ( ...
Tópico(s): Photonic and Optical Devices
2016 - American Physical Society | Physical Review Letters
... 1378–1385; Foundas, A. L., Bollich, A. M., Feldman, J., Corey, D. M., Hurley, M., & Lemen, L. C. et ...
Tópico(s): Neurobiology of Language and Bilingualism
2007 - Elsevier BV | Brain and Language
Steven R. Feldman, Corey Pelletier, Kathleen Wilson, Rina Mehta, Matthew Brouillette, David M. Smith, Machaon Bonafede,
Biologics and apremilast have advanced psoriasis management by adding treatment options. This study evaluated persistence, adherence and healthcare costs among biologic-naive patients receiving apremilast or biologics.Administrative claims data for adults starting apremilast or biologics from 1 January 2013 to 30 June 2016 were matched based on demographics.Apremilast (n = 703) and biologics (n = 1378) had similar baseline characteristics. 12-month persistence and adherence rates were similar. Adjusted ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2018 - Future Medicine | Journal of Comparative Effectiveness Research
Corey J. Mynatt, Kenneth A. Feldman, Lester D.�R. Thompson,
Isolated orbital infantile myofibroma are rare tumors in the head and neck. The mass-like clinical presentation and variable histologic features result in frequent misdiagnosis and potentially inappropriate clinical management. There are only a few reported cases in the English literature. Twenty-four patients with orbital infantile myofibroma or myofibromatosis were compiled from the English literature (Medline 1960–2011) and integrated with this case report. The patients included 14 males and 10 ...
Tópico(s): Oral and Maxillofacial Pathology
2011 - Springer Science+Business Media | Head and Neck Pathology
Roni Strier, Guy Feldman, Corey S. Shdaimah,
Abstract Social work introductory textbooks reflect myriad practical interests, pedagogical concerns, and theoretical considerations. However, they also present students with accepted views, dominant perspectives, and main discourses of knowledge. In light of this centrality, the present article examines the representation of the concept of “social class” in introductory textbooks as a way to look at the construction of the concept in social work education. Based on the content analysis study of ...
Tópico(s): Social Work Education and Practice
2012 - Taylor & Francis | Journal of Teaching in Social Work
Oded Béjà, Marcelino T. Suzuki, Eugene V. Koonin, L. Aravind, Andrew G. Hadd, Linh P. Nguyen, Rachel Villacorta, Mojgan Amjadi, Corey Garrigues, Stevan Jovanovich, Robert A. Feldman, Edward F. DeLong,
Cultivation‐independent surveys of ribosomal RNA genes have revealed the existence of novel microbial lineages, many with no known cultivated representatives. Ribosomal RNA‐based analyses, however, often do not provide significant information beyond phylogenetic affiliation. Analysis of large genome fragments recovered directly from microbial communities represents one promising approach for characterizing uncultivated microbial species better. To assess further the utility of this approach, we ...
Tópico(s): Bacteriophages and microbial interactions
2000 - Wiley | Environmental Microbiology
Caitlyn C. Gertz, Michelle K. Leach, Lisa K. Birrell, David C. Martin, Eva L. Feldman, Joseph M. Corey,
Neuritogenesis, neuronal polarity formation, and maturation of axons and dendrites are strongly influenced by both biochemical and topographical extracellular components. The aim of this study was to elucidate the effects of polylactic acid electrospun fiber topography on primary motor neuron development, because regeneration of motor axons is extremely limited in the central nervous system and could potentially benefit from the implementation of a synthetic scaffold to encourage regrowth. In this ...
Tópico(s): RNA Interference and Gene Delivery
2010 - Wiley | Developmental Neurobiology
Anne L. Foundas, Angela M. Bollich, Judith F. Feldman, David M. Corey, Megan Hurley, Lisa Lemen, Kenneth M. Heilman,
Objective: To learn if people with persistent developmental stuttering and atypical anatomy of their auditory temporal cortex have, when compared to control subjects, changes in fluency induced with delayed auditory feedback (DAF). Background: DAF improves fluency in many individuals who stutter, and induces dysfluency in some normal people. The planum temporale (PT), a portion of auditory temporal cortex, is anatomically atypical in some adults who stutter and atypical anatomy might induce aberrant function. ...
Tópico(s): Neurobiology of Language and Bilingualism
2004 - Lippincott Williams & Wilkins | Neurology
Pascal N. Tyrrell, Paul Corey, Brian M. Feldman, Earl D. Silverman,
Physicians often assess the effectiveness of treatments on a small number of patients. Multiple-baseline designs (MBDs), based on the Wampold-Worsham (WW) method of randomization and applied to four subjects, have relatively low power. Our objective was to propose another approach with greater power that does not suffer from the time requirements of the WW method applied to a greater number of subjects.The power of a design that involves the combination of two four-subject MBDs was estimated using ...
Tópico(s): Advanced Causal Inference Techniques
2013 - Elsevier BV | Journal of Clinical Epidemiology
Steven R. Feldman, Corey Pelletier, Kathleen Wilson, Rina Mehta, Matthew Brouillette, David M. Smith, Machaon Bonafede,
Aim: We evaluated treatment patterns and healthcare costs of initiating psoriatic arthritis (PsA) treatment with oral apremilast versus biologics. Methods: Claims data identified biologic-naive adults with PsA who initiated either apremilast or a biologic from 2013 to 2016. Results: Medication adherence was similar at 12 months (76.9 vs 73.4%; p = 0.175) between apremilast (n = 381) and matched biologic (n = 761) patients. Apremilast users had $12,715 lower total costs per-patient-per-month (p < 0.001), largely ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2019 - Future Medicine | Journal of Comparative Effectiveness Research
Peter R. Feldman, Pietro Gentile, Charles Piwko, Hendrik M. Motswaledi, Samantha Gorun, Jacob Pesachov, Michael L. Markel, Maxwell I. Silver, Megan Brenkel, Oriel J. Feldman, Corey L. Kamen, Elizabeth Uleryk, Jaime Guevara‐Aguirre, Klaus M. Fiebig,
Background Androgenetic alopecia (AGA) affects almost half the population, and several treatments intending to regenerate a normal scalp hair phenotype are used. This is the first study comparing treatment efficacy response and resistance using standardized continuous outcomes. Objective To systematically compare the relative efficacy of treatments used for terminal hair (TH) regrowth in women and men with AGA. Methods A systematic literature review was conducted (from inception to August 11, 2021) ...
Tópico(s): Facial Rejuvenation and Surgery Techniques
2023 - Frontiers Media | Frontiers in Medicine
Corey C. Foster, Chad G. Rusthoven, David J. Sher, Lawrence E. Feldman, Mary Pasquinelli, Michael T. Spiotto, Matthew Koshy,
Adjuvant chemotherapy is routinely offered post-surgical resection for early stage non-small-cell lung cancer (NSCLC) ≥4 cm; however, its role following definitive stereotactic body radiotherapy (SBRT) has not been well defined. We investigated the association between receipt of adjuvant chemotherapy post-SBRT and overall survival (OS) for patients with T1-T3N0M0 NSCLC in the National Cancer Database (NCDB).The NCDB was queried for patients with T1-T3N0M0 NSCLC treated with definitive SBRT from 2004 ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2019 - Elsevier BV | Lung Cancer
Muhammad O. Awiwi, Mohamed Badawy, Akram M. Shaaban, Christine O. Menias, Jeanne M. Horowitz, Moataz Soliman, Corey T. Jensen, Ayman H. Gaballah, Juan J. Ibarra-Rovira, Myra Feldman, Mindy X. Wang, Peter S. Liu, Khaled M. Elsayes,
Tópico(s): Gynecological conditions and treatments
2022 - Springer Nature | Abdominal Radiology
Stephen A. Harrison, Vincent Wai‐Sun Wong, Takeshi Okanoue, Natalie Bzowej, Raj Vuppalanchi, Ziad Younes, Anita Kohli, Shiv Kumar Sarin, Stephen H. Caldwell, Naim Alkhouri, Mitchell L. Shiffman, Marianne Camargo, Georgia Li, Kathryn Kersey, Catherine Jia, Yanni Zhu, C. Stephen Djedjos, G. Mani Subramanian, Robert P. Myers, Nadege Gunn, Aasim Sheikh, Quentin M. Anstee, Manuel Romero‐Gómez, Michael Trauner, Zachary Goodman, Eric Lawitz, Zobair M. Younossi, Adrían Gadano, Marcelo Martins, Peter Angus, John Bate, Mark Danta, Jacob George, Alexander Hodge, Nickolas Kontorinis, S.A. Roberts, Santosh Sanagapalli, Richard Skoien, Alexander Thompson, Amany Zekry, Rudolf Stauber, Michael Trauner, Christophe Moreno, Hendrik Reynaert, Len Verbeke, Mário Reis Álvares‐da‐Silva, Edison Roberto Parise, Cláudia P. Oliveira, Roberta Chaves Araújo, Ana de Lourdes Candolo Martinelli, Meredith A. Borman, Natasha Chandok, Magdy Elkhashab, Hughie Fraser, Kelly Kaita, Mang Ma, Paul Marotta, Alnoor Ramji, Edward Tam, Eric M. Yoshida, Mark G. Swain, Giada Sebastiani, Denis Petrunia, Armand Abergel, Rodolphe Anty, Marc Bourlière, Jérôme Boursier, Christophe Bureau, Laurent Castéra, François Habersetzer, Christophe Hézode, V. de Lédinghen, Vincent Leroy, V. Loustaud‐Ratti, Philippe Mathurin, Stanislas Pol, Fabien Zoulim, Holger Hinrichsen, Patrick Ingiliz, Frank Lammert, Michael Manns, Jörn M. Schattenberg, Ingolf Schiefke, Christian Trautwein, Stefan Zeuzem, Aric J. Hui, K Li, Vincent Wai‐Sun Wong, Subrat Kumar Acharya, Abhijit Chowdhury, Ajay Duseja, Dharmesh Kapoor, Shrikant Mukewar, Shiv Kumar Sarin, Samir Shah, S. Shalimar, Ajit Sood, BV Tantry, Ziv Ben‐Ari, Helena Katchman, Rifaat Safadi, Ella Veitsman, Eli Zuckerman, Maurizia Rossana Brunetto, Pietro Lampertico, Alessandra Mangia, Takemi Akahane, Norio Akuta, Norio Akuta, Yuichiro Eguchi, Shigetoshi Fujiyama, Takuya Genda, Yoichi Hiasa, Akio Ido, Fusao Ikeda, Tadashi Ikegami, Kento Imajo, Yoshito Itoh, Motoh Iwasa, Yoshiyasu Karino, Naoya Kato, Takumi Kawaguchi, Miwa Kawanaka, Masahiro Kido, Tomoo Kobayashi, Masayuki Kurosaki, Yasushi Matsuzaki, Eiji Mita, Eishiro Mizukoshi, Takashi Nakahara, Hideyuki Nomura, Kazuo Notsumata, Takeshi Okanoue, Satoshi Saito, Hiroshi Sakugawa, Yoshiyuki Suzuki, Koichi Takaguchi, Akinobu Takaki, Tomoyuki Takashima, Saiyu Tanaka, Keiji Tsuji, Yoshiyuki Ueno, Takeji Umemura, Hirofumi Uto, Nobuyuki Yamashita, Mikio Yanase, Hiroshi Yatsuhashi, Masashi Yoneda, Wah‐Kheong Chan, Soek Siam Tan, Laura Garza, Alma Ladron de Guevara Cetina, Ronald M. Angeles, Francisca Martinez Silva, Karel van Erpecum, David Orr, Maciej Jabłkowski, Jerzy Jaroszewicz, José Manuel Ramos, Taufique Ahmed, Tiing Leong Ang, Yock Young Dan, Boon Bee George Goh, Kalaiyarasi Kaliyaperumal, C. C. Yip, Soon Koo Baik, Byoung Kuk Jang, Dae Won Jun, Won‐Ho Kim, Hyung Joon Kim, Ji Hoon Kim, Kwan Sik Lee, Chun Kyon Lee, Young-Suk Lim, Jun Yong Park, Won Young Tak, Salvador Augustín, Sebastián Pérez, Juan Caballería, José Luís, C Panero, José A. Rodríguez, Javier Crespo, Javier García‐Samaniego, Pere Ginés Gibert, M. Prieto, Manuel Romero‐Gómez, Juan Turnés, Jean‐François Dufour, Alberto Moriggia, I-Shyan Sheen, Jia‐Horng Kao, Pin‐Nan Cheng, Jee‐Fu Huang, Sheng‐Shun Yang, Wei‐Wen Su, Chi-Yi Chen, Rong‐Nan Chien, Gin‐Ho Lo, Chi-Jen Chu, Horng-Yuan Wang, Jui-Ting Hu, Yi‐Wen Huang, Kosh Agarwal, Michael Allison, Quentin M. Anstee, Andrew D. Austin, Andrew Fowell, Chin Lye Ch’ng, Pinelopi Manousou, Philip N. Newsome, Stephen Ryder, Arun Shankar, Manal F. Abdelmalek, Gary A. Abrams, Humberto Aguilar, Imtiaz Alam, Laura Alba, Naim Alkhouri, Alina M. Allen, Bashar Aqel, Luis A. Balart, A. Sidney Barritt, Jaideep Behari, Michael Bennett, David I. Bernstein, Bal Raj Bhandari, Maurizio Bonacini, Brian B. Borg, Kimberly Brown, Natalie Bzowej, Stephen H. Caldwell, Tawfik N. Chami, Allan Coates, Adolfo Cueli, Mitchell Davis, Andrew S. deLemos, Archita P. Desai, Billy Dunn, Nelson Henrique da Silva Ferreira, Michael Fine, Roberto Firpi-Morell, Curtis Freedland, B. Freilich, Michael Fuchs, Michael Galambos, Juan F. Gallegos‐Orozco, Greg Galler, Maged P. Ghali, Reem Ghalib, Satinder Gill, Marcum Gillis, Richard Gilroy, S. Gordon, Nadege Gunn, Dina Halegoua‐De Marzio, Mohamed A. Hassan, Tarek Hassanein, Robert Herring, John D. Hong, Jonathan Huang, Heidi Kabler, Zeid Kayali, W Knapple, Geetha Kolli, Kris V. Kowdley, Richard A. Krause, Eric Lawitz, Steven D. Lidofsky, Joseph K. Lim, Donald Lipkis, Rohit Loomba, Amar Mahgoub, Miguel Malespin, Richard Manch, Steven Mannis, Paul Manos, Thomas J. McDonald, Mark McKenzie, Edward Mena, Raphael B. Merriman, Martin Moehlen, Richard Murdoch Montgomery, Robert L. Murphy, Yamini Natarajan, Guy Neff, Mazen Noureddin, Grisell Ortiz‐Lasanta, Mangesh Pagadala, Keyur Patel, Heather Patton, Adam Peyton, Neville R. Pimstone, John Poulos, David Pound, Nikolaos Pyrsopoulos,
•Selonsertib was safe and inhibited its target (ASK1) but did not lead to fibrosis regression or reduce disease progression in NASH. •Improvement in liver fibrosis on biopsy was associated with improvement only in other histologic features. •Improvements in ELF score and liver stiffness by transient elastography correlated with a variety of clinical parameters. Background & Aims Apoptosis signal-regulating kinase 1 (ASK1) plays a key role in hepatocyte injury, inflammation, and fibrosis in non-alcoholic ...
Elsevier BV
Joseph M. Corey, David Y. Lin, Katherine B. Mycek, Qiaoran Chen, Stanley Samuel, Eva L. Feldman, David C. Martin,
Abstract Nerve injury, a significant cause of disability, may be treated more effectively using nerve guidance channels containing longitudinally aligned fibers. Aligned, electrospun nanofibers direct the neurite growth of immortalized neural stem cells, demonstrating potential for directing regenerating neurites. However, no study of neurite guidance on these fibers has yet been performed with primary neurons. Here, we examined neurites from dorsal root ganglia explants on electrospun poly‐ L ‐lactate ...
Tópico(s): Silk-based biomaterials and applications
2007 - Wiley | Journal of Biomedical Materials Research Part A
Daniel E. Schwed Lustgarten, Charuhas Deshpande, Charu Aggarwal, Liang-Chuan Wang, Vassiliki Saloura, Anil Vachani, Liping Wang, Leslie A. Litzky, Michael D. Feldman, Jenette Creaney, Anna K. Nowak, Corey J. Langer, Simona Inghilleri, Giulia Maria Stella, Steven Μ. Albelda,
PurposeThymidylate synthase (TS) is a potential predictor of outcome after pemetrexed (Pem) in patients with malignant pleural mesothelioma (MPM), and assays measuring TS levels are commercially marketed. The goal of this study was to further evaluate the value of TS and to study another potential biomarker of response, the enzyme, folyl-polyglutamate synthase (FPGS), which activates Pem intracellularly.MethodsLevels of TS and FPGS were semi-quantitatively determined immunohistochemically using H-scores ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2013 - Elsevier BV | Journal of Thoracic Oncology
Joseph M. Corey, Caitlyn C. Gertz, Bor‐Shuen Wang, Lisa K. Birrell, Sara Johnson, David C. Martin, Eva L. Feldman,
Aligned electrospun nanofibers direct neurite growth and may prove effective for repair throughout the nervous system. Applying nanofiber scaffolds to different nervous system regions will require prior in vitro testing of scaffold designs with specific neuronal and glial cell types. This would be best accomplished using primary neurons in serum-free media; however, such growth on nanofiber substrates has not yet been achieved. Here we report the development of poly(L-lactic acid) (PLLA) nanofiber ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2008 - Elsevier BV | Acta Biomaterialia
Galan Moody, Corey McDonald, A. Feldman, Todd E. Harvey, Richard P. Mirin, Kevin L. Silverman,
The amplitude and phase of a material's nonlinear optical response provide insight into the underlying electronic dynamics that determine its optical properties.Phase-sensitive nonlinear spectroscopy techniques are widely implemented to explore these dynamics through demodulation of the complex optical signal field into its quadrature components; however, complete reconstruction of the optical response requires measuring both the amplitude and phase of each quadrature, which is often lost in standard ...
Tópico(s): Quantum Information and Cryptography
2016 - Optica Publishing Group | Optica
Joseph M. Corey, Caitlyn C. Gertz, Thomas J. Sutton, Qiaoran Chen, Katherine B. Mycek, Bor‐Shuen Wang, Abbey A. Martin, Sara Johnson, Eva L. Feldman,
Abstract Influencing cell shape using micropatterned substrates affects cell behaviors, such as proliferation and apoptosis. Cell shape may also affect these behaviors in human neuroblastoma (NBL) cancer, but to date, no substrate design has effectively patterned multiple clinically important human NBL lines. In this study, we investigated whether Pluronic F108 was an effective antiadhesive coating for human NBL cells and whether it would localize three NBL lines to adhesive regions of tissue culture ...
Tópico(s): Skin and Cellular Biology Research
2009 - Wiley | Journal of Biomedical Materials Research Part A
Hana M. El Sahly, Lindsey R. Baden, Brandon Essink, Susanne Doblecki‐Lewis, Judith M. Martin, Evan J. Anderson, Thomas Campbell, Jesse L. Clark, Lisa A. Jackson, Carl J. Fichtenbaum, Marcus Zervos, Bruce Rankin, Frank Eder, Gregory Feldman, C Kennelly, Laurie J. Han-Conrad, Michael Levin, Kathleen M. Neuzil, Lawrence Corey, Peter B. Gilbert, Holly Janes, Dean Follmann, Mary Marovich, Laura Polakowski, John R. Mascola, Julie E. Ledgerwood, Barney S. Graham, Allison August, Heather Clouting, Weiping Deng, Shu Han, Brett Leav, Deb Manzo, Rolando Pajón, F. Schödel, Joanne E. Tomassini, Haiyu Zhou, Jacqueline M. Miller,
At interim analysis in a phase 3, observer-blinded, placebo-controlled clinical trial, the mRNA-1273 vaccine showed 94.1% efficacy in preventing coronavirus disease 2019 (Covid-19). After emergency use of the vaccine was authorized, the protocol was amended to include an open-label phase. Final analyses of efficacy and safety data from the blinded phase of the trial are reported.
Tópico(s): Animal Virus Infections Studies
2021 - Massachusetts Medical Society | New England Journal of Medicine
... article. I am also grateful to Sophie Kaiser, Corey Banks, Hilary Wong, Rusty Feldman, Adam Olin, Katherine Denby, Eugene Karlik, James Blakemore, ...
Tópico(s): Law, logistics, and international trade
2016 - UC Berkeley School of Law | Berkeley journal of international law
Stefania D’Amico, Corey M. Feldman,
Tópico(s): Global Financial Crisis and Policies
2024 - RELX Group (Netherlands) | SSRN Electronic Journal
Corey D. Cicci, Ashley Weiss, Cathyyen Dang, Matthew Stanton, Ryan Feldman,
The objective of this study was to evaluate clinical outcomes associated with time to administration and dose of four-factor prothrombin complex concentrate (4F-PCC) in patients with ICH on warfarin.This was a single-center retrospective analysis of patients with ICH on warfarin who received 4F-PCC.The site of the study was a large, Level I trauma, academic medical center with a dedicated neurologic intensive care unit and an emergency department (ED) that has approximately 72,000 visits annually. ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2022 - Wiley | Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
Melina E. Marmarelis, Abigail T. Berman, Dylan Scholes, Jeffrey C. Thompson, Abigail Doucette, Peter Gabriel, Joshua Bauml, Aditi P. Singh, Roger B. Cohen, Leslie A. Litzky, Cindy McGrath, Michael D. Feldman, Corey J. Langer, Erica L. Carpenter, Charu Aggarwal,
Tópico(s): Lung Cancer Diagnosis and Treatment
2021 - Elsevier BV | Journal of Thoracic Oncology
Ziyin Li, Chun-Bin Zou, Yi Yao, Martin A. Hoyt, Stephen McDonough, Zachary B. Mackey, Philip Coffino, Ching C. Wang,
... from Verma et al. (15Verma R. Chen S. Feldman R. Schieltz D. Yates J. Dohmen J. Deshaies R.J. Mol. Biol. Cell. 2000; 11: 3425-3439Crossref PubMed Scopus (461) Google Scholar). Lactacystin was purchased from Professor E. J. Corey, Harvard University. All the other chemicals used in ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2002 - Elsevier BV | Journal of Biological Chemistry
Jeff Min, David B. Badesch, Murali M. Chakinala, Jean Elwing, Robert P. Frantz, Evelyn M. Horn, James R. Klinger, Matthew R. Lammi, Sula Mazimba, Jeffrey S. Sager, Oksana A. Shlobin, Marc A. Simon, Thenappan Thenappan, Daniel Grinnan, Corey E. Ventetuolo, Nadine Al‐Naamani, Abhijit Raval, Amresh Raina, Anna R. Hemnes, Charles D. Burger, D. Dunbar Ivy, Delphine Yung, Dianne Zwicke, Erika B. Rosenzweig, Gautam Ramani, Granthem Farr, H. James Ford, James Runo, Jeffrey R. Fineman, Jeremy Feldman, J. Swisher, John Ryan, John W. McConnell, Kenneth W. Presberg, Kishan S. Parikh, Linda Cadaret, Mark Avdalovic, Michael Schmidt Duncan, Michael Eggert, Nidhy P. Varghese, Paul Boyce, Peter J. Leary, Raymond Foley, R. James White, Robert P. Frantz, Roham T. Zamanian, Russel Hirsch, Sahil Bakshi, Sonja Bartolome, Steven Kawut, Stephen C. Mathai, Teresa De Marco, Timothy Williamson, Todd Bull,
Tópico(s): Pulmonary Hypertension Research and Treatments
2020 - American Thoracic Society | American Journal of Respiratory and Critical Care Medicine
B Bader, Sang Su Oh, Matthew Old, Joseph M. Corey, Eva L. Feldman, Norman D. Hogikyan,
Problem The ability to reliably restore physiologic movement to a paralyzed vocal fold is not yet in hand. Muscle‐nerve‐muscle (M‐N‐M) neurotization is a process whereby axons sprouting from within an innervated muscle are directed toward a denervated muscle via a neural conduit. Given the paired laryngeal musculature, M‐N‐M neurotization holds promise for restoring physiologic vocal fold movement in cases of unilateral paralysis. This study is aimed at exploring the effectiveness of M‐N‐M neurotization ...
Tópico(s): Dysphagia Assessment and Management
2008 - Wiley | Otolaryngology
Gary M. Ksander, Reynalda deJesus, Andrew Yuan, Cynthia A. Fink, Michael A. Moskal, Eric A. Carlson, Paivi J. Kukkola, Natalie A. Bilci, Eli Wallace, Alan D. Neubert, David N. Feldman, Therese C. Mogelesky, Kevin Poirier, Michael R. Jeune, Ronald E. Steele, Jong Wasvery, Zouhair F. Stephan, Edna Cahill, Randy L. Webb, Aida E. Navarrete, Warren Lee, Joyce Corey Gibson, Natalya Alexander, H. Sharif, Ashok Hospattankar,
The synthesis and biological activities of biarylamide-substituted diaminoindanes as microsomal triglyceride transfer protein (MTP) inhibitors are described. One of the more potent compounds, 8aR, inhibited both the secretion of apoB from Hep G2 cells and the MTP-mediated transfer of triglycerides between synthetic acceptor and donor liposomes with IC(50) values of 0.7 and 70 nM, respectively. In normolipidemic rats and dogs, oral administration of 8aR dose-dependently reduced both plasma triglycerides ...
Tópico(s): Protein Degradation and Inhibitors
2001 - American Chemical Society | Journal of Medicinal Chemistry
Jeff Min, Rui Feng, David B. Badesch, Erika B. Rosenzweig, Charles D. Burger, Murali M. Chakinala, Teresa De Marco, Jeremy Feldman, Anna R. Hemnes, Evelyn M. Horn, Matthew R. Lammi, Stephen C. Mathai, John W. McConnell, Kenneth W. Presberg, Jeffrey C. Robinson, Jeffrey S. Sager, Oksana A. Shlobin, Marc A. Simon, Thenappan Thenappan, Corey E. Ventetuolo, Nadine Al‐Naamani, Roblee P. Allen, Sonja Bartolome, Raymond L. Benza, Todd Bull, Linda Cadaret, Michael Eggert, Jean Elwing, Jeffrey R. Fineman, Raymond Foley, H. James Ford, Robert P. Frantz, Russel Hirsch, James Grinnan, D. Dunbar Ivy, Steven M. Kawut, Jamie L.W. Kennedy, James R. Klinger, Peter J. Leary, Sula Mazimba, Gautam Ramani, Amresh Raina, James Runo, J. Swisher, John Ryan, Nidhy P. Varghese, R. James White, Timothy Williamson, Delphine Yung, Roham T. Zamanian, Dianne Zwicke,
Obesity is associated with pulmonary arterial hypertension (PAH), but its impact on outcomes such as health-related quality of life (HRQoL), hospitalizations and survival is not well understood. To assess the effect of obesity on health-related quality of life (HRQoL), hospitalizations and survival in patients with PAH. We performed a cohort study of adults with PAH from the Pulmonary Hypertension Association Registry, a prospective multicenter registry. Multivariate linear mixed effects regression ...
Tópico(s): Vascular Anomalies and Treatments
2020 - American Thoracic Society | Annals of the American Thoracic Society