Giles Smith, Andrew Robson, Lucy Alexander, Janice Turner, Christina Hardyment, John McNamara, Jon Ashworth, David Adams, Stella Shamoon, Donald MacGillivray, Matthew Syed, Juliet Clough, Richard Ellis, Jade Johnson, Jane MacQuitty, Jasper Rees, Simon Hills, David Isaac, Christopher Somerville, Paul Hoggart, Mark Souster, Ramita Navai, Emma Haughton, Martin Richards, John Mulvey, Todd Slaughter, President, Hattie Ellis, Clare Lazaro, Snowflakes, Michael Evans Defence Editor, Philip Howard, Jan Parker, Camilla Cavendish, Serena MacKesy, Christine Seib, Roger Knight, Suna Erdem, James Bone, Calre Lazaro, Matthew Pryor Zurich Premiership, Nic Hopkins, Paul Herrington, Alexandra Frean Social Affairs Correspondent, Deborah Moggach, Roger Mather, Elizabeth Judge, Kate Reardon, Harry Frere, William T. Orton, CC, John Previte, GS, Martin Aston, Slan Blackmore, Keith Peters, John Bungey, Martin Wiseman, Ron Zimmern, Director, Tempus, Alastair Campbell, Ben Webster Transport Correspondent, Mark Griffiths, Nancy Durrant, Georgia Glynn Smith, John Clarke, Vinny Lee, Gulu Ezekiel, Rob Cassy, John Downing, Steve Keenan, Paul Cocksedge, Nicholas Royle, Tom Bawden, Steve Bird, Rachel Holmes, Gioconda, Joe Morgan, Grainne Gilmore, Jill Dupleix, Charlie Charalambous, Dan Sabbagh, Jonathan Romain, Nigel Williamson, Peter Ackroyd, Candida Crewe, Jo Morris, Helen Monks, Alan Hamilton, Oliver Wright, Oliver Wright Health Correspondent, Anthony Browne Brussels Correspondent, Mike Robertshaw, James Delingpole, Nick Wyke, Jonathan Margolis, Roland Watson, David Hands, Jenni Murray, Helen Rumbelow, Stefanie Marsh, D. B. Wigg, Ian McIntyre, Genevieve Fox, Tim Teeman, Caroline Merrell Banking Correspondent, Derwent May, Arwa Haider, Nadia Raafat, Graham Wood, Ivan Hewett, Jeff Leviss, Aggie MacKenzie, Paula Hawkins, Peter Paphides, Antonia Senior and Tim Evershed, David Rowan, Emma Freud, Mary Gold, Daniel McGrory, Tony Halpin Education Editor, Oliver Kay, Luke Coppen, Felipe Fernandez-Armesto, Richard Cork, Stephen Anderton, Amber Cowan, Ed Potton, Elizabeth Usherwood, Mark Atherton, Jonah Goldberg, John Westerby, Michael Theodoulou, Rick Broadbent, Xan Rice and Mark Atherton, Lulu, singer, Tom Baldwin, Jan Baldwin, Linda Evans, Chris Power, John Hopkins, Gabriella Gamini, Neel Mukherjee, Simon de Bruxelles, Rob Wright, Nic Hopkins and Dan Sabbagh, Elaine Monaghan, Amanda Platell, EVA McCubbin, Sarah Turner, Stuart Miles, AF, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Gavin Martin, Raymond Keene, Neil Armstrong, Adam Sage, Rod Liddle, Perou, Bart Plantenga, Bruce Dessau, Ellen Connolly, Dillwyn Williams, Jeremy Page, Richard Fortey, Andrew G. Marshall, Charles Gant, Chris Campling, Tim O'sullivan, Dale Cherry, Richard Owen, Mizuha Kaizumi, Alex Hawkes, Oliver August, Peter Dixon, Ronald Hutton, Scott McLeish, S. E. Harris, Margaret Reynolds, David Hands Rugby Correspondent, Tom Dart, James Collard, Simon O'connell, David Rutley, Director of financial services, Adam Fresco, Tom Baldwin and Roland Watson, Anna Frame, Nigel Kendall, Nick Szczepanik, Joanna Pitman, Dominic Kennedy, Giles Whittell, Robert Crampton, Ian Johns, Craig Lord, Daniel Bown, Deborah King, Ashling O'connor, Matthew Parris, Ian McCurrach, Virginia Blackburn, Jennai Cox, Jim Wishart, Amanda Craig, Jonathan Rendall, John Lister-Kaye, Russell Jenkins, Rebecca Ley, Sheila Keating, Alan Lee, Tim Wapshott, Iain Finlayson, DC, Anne Dixey, Helen Pridham, Phil Knott, Bess Twiston Davies, Ben Webster, David Charter Chief Political Correspondent, Alison Gibson, Ted Harrison, David Sinclair, Sara Wheeler, Annabelle Thorpe, Lewis Stuart, John Naish, Martin Waller, Mark Henderson, Chris Ayres, Michael Horsnell, Christopher Irvine, RC, Carl Mortished International Business Editor, Lisa Verrico, Nigel Hawkes and Sam Lister, Nigel Hawkes Health Editor, Sarah Butler, Benedict Nightingale, Douglas Rogers, Darian Leader, Anna Shepard, Angus Batey, Stephen Dalton, Tulip Bemrose, Leo Lewis, Bill Edgar, Paul Connolly, Fred Dellar, Michael Evans Defence Editor and Sam Coates, James Christopher, Abigail Rayner, Michael Evans, Alan Lee Racing Correspondent, Sebastian Smith, Alan Jackson, Owen Slot, John Jones, Mark Harrison, Sue Davis, Jan Raath, Edward Gorman Sailing Correspondent, Richard Ford, Peter Klinger, Joe Bolger, Doug Counsell, R. M. Stephenson,
... Mor Neil Sedaka Oh Carol (Beer Family) Blues Corey Marris Misslssippi to Malli (Roumder) no title A ...
2004 - Gale Group | TDA
Brian E. Hawes, Louis M. Luttrell, Tim van Biesen, Robert J. Lefkowitz,
... PubMed Google Scholar, 25.Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ... and PIP3 production(25.Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ... PubMed Google Scholar, 25.Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
1996 - Elsevier BV | Journal of Biological Chemistry
Takashi Akasaki, Hirofumi Koga, Hideki Sumimoto,
... 1660Crossref PubMed Google Scholar,30Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ... 3,4,5)P3 (30Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ... PI3K in human neutrophils (30Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
1999 - Elsevier BV | Journal of Biological Chemistry
Constantine A. Gatsonis, Denise R. Aberle, Christine D. Berg, William C. Black, Timothy R. Church, Richard M. Fagerstrom, Barbara Galen, Ilana F. Gareen, Jonathan Goldin, John K. Gohagan, Bruce J. Hillman, C. Carl Jaffe, Barnett S. Kramer, David A. Lynch, Pamela M. Marcus, Mitchell D. Schnall, Daniel C. Sullivan, Dorothy Sullivan, Carl J. Zylak, Christopher H. Cagnon, Dianna D. Cody, Glenn Fletcher, Michael Flynn, Philip F. Judy, Randell Kruger, Frederick J. Larke, Michael F. McNitt‐Gray, Thomas Payne, J. Anthony Seibert, Xizeng Wu, Gerald F. Abbott, Judith K. Amorosa, R. Graham Barr, Phillip M. Boiselle, Caroline Chiles, Robert A. Clark, Lynn Coppage, Robert Falk, Elliot K. Fishman, David Gemmel, Jonathan Goldin, Eric T. Goodman, Eric Hart, Todd R. Hazelton, Elizabeth Johnson, Ella A. Kazerooni, Barbara L. McComb, Geoffrey McLennan, Reginald F. Munden, James Ravenel, Michael A. Sullivan, Stephen J. Swensen, Drew A. Torigian, Kay H. Vydareny, John A. Worrell, Peter W. Balkin, Mona N. Fouad, Matthew T. Freedman, Kavita Garg, Edward P. Gelmann, David S. Gierada, William G. Hocking, Subbarao Inampudi, Claudine Isaacs, Paul A. Kvale, Howard Mann, William Manor, Hrudaya Nath, Douglas J. Reding, David L. Spizarny, Diane C. Strollo, John Waltz, Mei‐Hsiu Chen, Fenghai Duan, Grant Izmirilian, Paul F. Pinsky, Philip C. Prorok, Anthony B. Miller, Martin J. Edelman, William K. Evans, Robert S. Fontana, Mitchell Machtay, Kenneth W. Clark, Kathy L. Clingan, Melissa Ford, Guillermo Márquez, Steven M. Moore, Peter Ohan, Thomas Payne, Steven Peace, Jennifer L. Rosenbaum, R. Graham Barr, William C. Black, Drew A. Torigian, Kay H. Vydareny, John A. Worrell, Robert C. Young, David S. Alberts, David L. DeMets, Peter Greenwald, Paula Jacobs, Theresa C. McLoud, David P. Naidich, James M. Tatum, Edward A. Sausville, Wylie Burke, Gene Colice, Brenda K. Edwards, Scott Emerson, John Fletcher, Sylvan Green, Russell Harris, Jeffrey S. Klein, Edward L. Korn, Robert Mayer, Joe V. Selby, David W. Sturges, Bruce W. Turnbull, Thomas J. Watson, Stephen Baylin, Neil E. Caporaso, Philip A. Dennis, Steve Dubinett, Wilbur A. Franklin, William E. Grizzle, Fred R. Hirsch, Pierre P. Massion, Kathy McKeeta-Frobeck, John D. Minna, Edward F. Patz, Margaret R. Spitz, Christine B. Berg, Donald K. Corle, Ping Hu, Grant Izmirlian, Jennifer Gaegler, Susan Hoffman, Charles Jackson, Erin O. Lange, Evanthia Papadopoulos, Constantine Gatsonis, Ilana F. Gareen, Charles Apgar, Anna Boyle, Tom Caldwell, Nancy Fredericks, Deborah Harbison, Donna Hartfeil, Sharon Jones, Steve King, Irene Mahon, Rosa Medina, Cindy Masiejczyk, Peter Zamora, Hank Brastater, Vish Iyer, Jincy George, Dinakar Gopalakrishnan, Patricia Blair, Michael Bradley, C. Crozier, M. Oh, Nicole Spiese, Chris Steward, Mary Kelly-Truran, Tess Thompson, Erin Cunningham, Anthony Levering, Kathleen McMurtrie, Michael Nahill, Sharlene Snowden, Kesha Smith, Fraser Wilton, Timothy T. Welsh, Rex Welsh, Wendell Christie, Stephanie Clabo, Roberta Clune, Natalie Cunningham, J. C. Upshaw Downs, Lindsey Dymond, Julianne Falcone, Shani Harris, Pam Harvey, Jane E. Hill, Laura Hill, Donna Letizia, Kendrick Looney, Hugh McGinley, Angelee Mean, Marcella Moore, Ryan J. Norton, Valentina Ortico, Sophia Sabina, R. Cabrera Sole, Jo Ann Stetz, Arnold Ssali, John Stubblefield, Tina Taylor, Shovonna White, Jiahong Lu, Amanda Adams, Sarah E. Baum, Meridith Blevins, Patricia S. Fox, Vincent Girardi, Jeremy Gorelick, EDWARD LIVINGSTON HUNT, Quentin McMullen, Karthikeyan Meganathan, Regina Rendas‐Baum, Jo Rean D Sicks, Bradley S. Snyder, Melanie Yeh, Maryann Duggan, Cheryl Souza, Jack Cahill, Brenda Brewer, Barbara O’Brien, G. Devereux, Melissa S. Fritz, Miriam Galbraith, Judith Harkins, Kristen Keating, Kirk Midkiff, Usha Singh, Thea Palmer Zimmerman, Nancy Payte, Helen Price, Clifford Caughman, Ramachandra Chanapatna, Mike Florzyk, Annabelle Lee, Alan Morgan, Jennifer Yang, L. Ellen Martinusen, June McSwain, Rhonda Rosario, Jagdish Singh, R. Adam DeBaugh, Sharan Campleman, Mary Mesnard, Lawrence R. Ragard, Terry Lewis, Lois Roberts, Vijayasri Narayanaswami, Vanessa Ralda, William C. Lake, Thomas Riley, Jonathan B. Clapp, Joe Austin, Brian K. Irons, Fang F. Xu, Gordon C. Jones, Michael A. Young, Andrew Goodman, Crissy Kibic, Patricia Sheridan, Nancy Kadish, Denise Moline, Rachel Phillips, Michele Adkinson, David Creed, Tammy DeCoste, Debbie Gembala, Sally Hurst, Elizabeth M. King, Joy Knowles, Pamela McBride, Patricia Pangburn, Judy Preston, Karen T. Stokes, Patricia Tesch, Susan Wenmoth, Linda Galocy, Deanna Mandley, Gail Orvis, Alphonso Dial, Letitia Clark, Lawrence Cohen, Joanne Gerber, Carlos Jamis‐Dow, Erini Makariou, Edward R. Smith, Amy Garrett, Colleen McGuire, Sarah Neff, Tara Riley, Sara Cantrell, Glynis Marsh, Chrispina Wray, Baigalmaa Yondonsambuu, Ulander Giles, Morgan Ford, Venus Brown, Amy Lita Evangelista,
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older current and former heavy smokers for early detection of lung cancer, which is the leading cause of cancer-related death in the United States. Five-year survival rates approach 70% with surgical resection of stage IA disease; however, more than 75% of individuals have incurable locally advanced or metastatic disease, the latter ...
Radiological Society of North America
Weidong Wu, Xinchao Wang, Wenli Zhang, William Reed, James M. Samet, Young E. Whang, Andrew J. Ghio,
... factor receptors and integrins (25Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2003 - Elsevier BV | Journal of Biological Chemistry
Bingsheng Li, Wu Ma, Howard Jaffe, Yali Zheng, Satoru Takahashi, Lei Zhang, Ashok B. Kulkarni, Harish C. Pant,
... well as in vitro (47Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ...
Tópico(s): Cancer Mechanisms and Therapy
2003 - Elsevier BV | Journal of Biological Chemistry
Mingyao Liu, Bo Yu, Osamu Nakanishi, Thomas Wieland, Melvin I. Simon,
... Scholar), inositol trisphosphate kinases (9Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ...
Tópico(s): Protein Structure and Dynamics
1997 - Elsevier BV | Journal of Biological Chemistry
Michael G. Thompson, Steven C. Mackie, Amanda Thom, Robert M. Palmer,
... of phosphatidylinositol-3-kinase (61Stephens L. Eguinoa A. Corey S. Jackson T. Hawkins P.T. EMBO. J. 1993; 12: 2265-2273Crossref ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
1997 - Elsevier BV | Journal of Biological Chemistry
Sarah J. Turner, Jan Domin, Michael D. Waterfield, Stephen G. Ward, John Westwick,
... p110 PI 3-kinase (36Stephens L. Eguinoa A. Corey S. Jackson T.R. Hawkins P.T. EMBO J. 1993; 12: 2265-2273Crossref ...
Tópico(s): interferon and immune responses
1998 - Elsevier BV | Journal of Biological Chemistry
Emily W. Ruell, Corey A. Handelsman, Charlotte Hawkins, Helen R. Sofaer, Cameron K. Ghalambor, Lisa M. Angeloni,
The evolution of male ornamentation often reflects compromises between sexual and natural selection, but it may also be influenced by phenotypic plasticity. We investigated the developmental plasticity of male colour ornamentation in Trinidadian guppies in response to two environmental variables that covary in nature: predation risk and food availability. We found that exposure to chemical predator cues delayed the development of pigment-based colour elements, which are conspicuous to visual-oriented ...
Tópico(s): Neurobiology and Insect Physiology Research
2013 - Royal Society | Proceedings of the Royal Society B Biological Sciences
David Hawkins, Corey J. Lum, Diane Gaydos, Russell Dunning,
Warm-up exercises are often advocated prior to strenuous exercise, but the warm-up duration and effect on muscle–tendon behavior are not well defined. The gastrocnemius–Achilles tendon complexes of 18 subjects were studied to quantify the dynamic creep response of the Achilles tendon in-vivo and the warm-up dose required for the Achilles tendon to achieve steady-state behavior. A custom testing chamber was used to determine each subject's maximum voluntary contraction (MVC) during an isometric ankle ...
Tópico(s): Sports Performance and Training
2009 - Elsevier BV | Journal of Biomechanics
Ambrose Lane, Arrealia Gavins, Ar’Reon Watson, Celene E. Domitrovich, Chioma M. Oruh, Christina Morris, Claire Boogaard, Claudine Sherwood, Destiny N. Sharp, Dominique Charlot‐Swilley, Erica E. Coates, Erin T. Mathis, Gail Avent, Hillary A. Robertson, Huynh‐Nhu Le, J. Corey Williams, Janaíre Hawkins, Jenise Patterson, Jessica X. Ouyang, Karyn Hartz, LEE SAVIO BEERS, Linwood Cole, Matthew G. Biel, Nia Bodrick, Noel Bravo, Randall S. Baylor, Ruthie Arbit, Sabrina F. Zuskov, Sarah B. Hoffman, Satyani K. L. McPherson, Sharon Singh, Sharra E. Greer, Simone N. Banks-Mackey, Susan Caleb, Stéphanie Thomas, Torrian Brent, Travis Spencer,
Structural racism-the ways that institutional policies, practices, and other norms operate to create and sustain race-based inequities1-has historically been foundational to the operations of academic medical centers and research institutions. Since its inception, academic medicine has depended on the exploitation of vulnerable communities to achieve medical, educational, and research goals.2 Research practices have long ignored or taken advantage of the individuals purportedly benefiting from the ...
Tópico(s): Racial and Ethnic Identity Research
2021 - Elsevier BV | Journal of the American Academy of Child & Adolescent Psychiatry
Jaclyn C. Scott, Doug E. Brackney, Corey L. Campbell, Virginie Bondu-Hawkins, Brian Hjelle, G. D. Ebel, Ken E. Olson, Carol D. Blair,
The exogenous RNA interference (RNAi) pathway is an important antiviral defense against arboviruses in mosquitoes, and virus-specific small interfering (si)RNAs are key components of this pathway. Understanding the biogenesis of siRNAs in mosquitoes could have important ramifications in using RNAi to control arbovirus transmission. Using deep sequencing technology, we characterized dengue virus type 2 (DENV2)-specific small RNAs produced during infection of Aedes aegypti mosquitoes and A. aegypti Aag2 ...
Tópico(s): Insect Resistance and Genetics
2010 - Public Library of Science | PLoS neglected tropical diseases
J.C. Corey, Richard H. Hawkins, R. F. Overman, R. E. Green,
Abstract When fluid in a porous medium is displaced by a second fluid that is miscible with the first, a transition zone exists between the two. The length and location of this transition zone in a soil column is difficult to measure in situ . When one of the fluids contains D 2 O as the major component, a new procedure, the gamma‐photoneutron method, readily measures this transition zone. This method permits precise measurements of the average concentration of heavy water (D 2 O) at selected locations ...
Tópico(s): Geothermal Energy Systems and Applications
1970 - Wiley | Soil Science Society of America Journal
Len Stephens, A. Eguinoa, Shawn Corey, Trevor Jackson, Phillip T. Hawkins,
Phosphoinositide 30H-kinase (PI3K) activities are thought to be critical regulatory enzymes in a new intracellular signalling pathway, the activation of which results in the rapid accumulation of a putative signalling molecule, phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5) P3]. To date, activation of PI3K has always correlated with its recruitment into complexes containing protein tyrosine kinases (PTK). Here we report that agonists which utilize G-protein mediated transduction pathways ...
Tópico(s): Drug Transport and Resistance Mechanisms
1993 - Springer Nature | The EMBO Journal
Hossein Borghaei, Katherine Alpaugh, Gunnar Hedlund, G. Forsberg, Corey J. Langer, André Rogatko, Robert D. Hawkins, Svein Dueland, Ulrik Lassen, Roger B. Cohen,
Two phase I studies were conducted of ABR-217620 alone or in combination with docetaxel. This is a recombinant fusion protein consisting of a mutated variant of the superantigen staphylococcal enterotoxin E (SEA/E-120) linked to fragment antigen binding moiety of a monoclonal antibody recognizing the tumor-associated antigen 5T4.Patients with non-small-cell lung cancer (NSCLC), pancreatic cancer (PC), and renal cell cancer (RCC) received 5 daily boluses of ABR-217620 (3-month cycles) in escalating doses ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2009 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
David J.A. Jenkins, Aneal Khan, Alexandra L. Jenkins, Roger Illingworth, Anuradhe S. Pappu, Thomas M.S. Wolever, Vladimir Vuksan, G.C. Buckley, A. Venketeshwer Rao, Stephen C. Cunnane, Furio Brighenti, Meredith Hawkins, Mohamed Abdolell, Paul Corey, Robert L. Patten, Robert G. Josse,
Nibbling has been reported to decrease serum cholesterol under fasting conditions, as well as the incidence of cardiovascular disease. It has been suggested that these effects are partly attributable to reduced concentrations of serum insulin, which are also observed. However, data on the effects of nibbling on serum lipids throughout the day are not available, nor is it known how nibbling affects serum uric acid as a further insulin-related risk factor for cardiovascular disease. We have attempted ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
1995 - Elsevier BV | Metabolism
Seth C. Hawkins, Corey Winstead,
Abstract Wilderness medicine classes are widely available to archaeologists and field scientists, but because wilderness medicine is an unregulated field, knowing what the various courses and products mean can be difficult. Based on the education chapter in the recently published textbook Wilderness EMS, this article—written by same two authors as the book—explores a number of topics relevant for the field scientist, program director, or administrator seeking to obtain wilderness medicine training ...
Tópico(s): Travel-related health issues
2021 - Cambridge University Press | Advances in Archaeological Practice
Fusheng Li, Uma Malhotra, Peter B. Gilbert, Natalie Hawkins, Ann Duerr, M. Juliana McElrath, Lawrence Corey, Steven G. Self,
Dozens of human immunodeficiency virus-type 1 (HIV-1) vaccine candidates specifically designed to elicit cytotoxic T-lymphocyte (CTL) responses have entered the pipeline of clinical trials. Evaluating the immunogenicity and potential efficacy of these HIV-1 vaccine candidates is challenging in the face of the extensive viral genetic diversity of circulating strains. Standardized peptide reagents to define the magnitude and potential breadth of the T-cell response, especially to circulating strains ...
Tópico(s): Immunotherapy and Immune Responses
2006 - Elsevier BV | Vaccine
Seth J. Corey, A. Eguinoa, K. Puyana-Theall, Joseph B. Bolen, Lewis C. Cantley, Faustino Mollinedo, Trevor Jackson, Phillip T. Hawkins, Len Stephens,
... by this author P.T. Hawkins P.T. Hawkins Department of Pediatrics, University of Pittsburgh, PA 15213. Search for more papers by this author L.R. Stephens L.R. Stephens Department of Pediatrics, University of Pittsburgh, PA 15213. Search for more papers by this author S. Corey S. Corey Department of Pediatrics, University of Pittsburgh, ...
Tópico(s): Cell Adhesion Molecules Research
1993 - Springer Nature | The EMBO Journal
Victor E. Ortega, Michelle Daya, Stanley J. Szefler, Eugene R. Bleecker, Vernon M. Chinchilli, Wanda Phipatanakul, Dave Mauger, Fernando D. Martínez, Esther Herrera‐Luis, María Pino-Yanes, Gregory A. Hawkins, Elizabeth J. Ampleford, Susan J. Kunselman, Corey Cox, Leonard B. Bacharier, Michael D. Cabana, Juan Carlos Cardet, Mario Castro, Loren C. Denlinger, Celeste Eng, Anne M. Fitzpatrick, Fernando Holguín, Donglei Hu, Daniel J. Jackson, Nizar N. Jarjour, Monica Kraft, Jerry A. Krishnan, Stephen C. Lazarus, Robert F. Lemanske, John J. Lima, Njira Lugogo, Angel C. Y. Mak, Wendy C. Moore, Edward T. Naureckas, Stephen P. Peters, Jacqueline A. Pongracic, Satria P. Sajuthi, Max A. Seibold, Lewis J. Smith, Julian Solway, Christine A. Sorkness, Sally E. Wenzel, Steven R. White, Esteban G. Burchard, Kathleen C. Barnes, Deborah A. Meyers, Elliot Israel, Michael E. Wechsler, Tarig Ali‐Dinar, Lisa Bartnikas, Sachin N. Baxi, Avraham Beigelman, Mindy Benson, Kathryn Blake, Elizabeth Burke‐Roberts, Manuela Cernadas, James F. Chmiel, Ronina Covar, Emily DiMango, Jonathan M. Gaffin, Deborah A. Gentile, N. Grossman, Marissa Hautpman, David Kantor, Harsha Kumar, Craig LaForce, Jason E. Lang, Dayna Long, Margee Louisias, Wayne J. Morgan, James N. Moy, Ross Myers, J. Tod Olin, Perdita Permaul, Loretta G. Que, Hengameh Raissy, Rachel G. Robison, Kristie Ross, William J. Sheehan, Lisa Sullivan-Vedder, Lakeia Wright,
Background Pharmacogenetic studies in asthma cohorts, primarily made up of White people of European descent, have identified loci associated with response to inhaled beta agonists and corticosteroids (ICSs). Differences exist in how individuals from different ancestral backgrounds respond to long-acting beta agonist (LABA) and ICSs. Therefore, we sought to understand the pharmacogenetic mechanisms regulating therapeutic responsiveness in individuals of African descent. Methods We did ancestry-based ...
Tópico(s): Pharmaceutical studies and practices
2021 - Elsevier BV | The Lancet Child & Adolescent Health
George L. Bakris, Manish Saxena, Anil Gupta, Fadi Chalhoub, Jong-Tae Lee, Daniel Stiglitz, Nune Makarova, Nitender Goyal, Weinong Guo, Dion Zappe, Akshay S. Desai, George Carr, Christopher Case, Lauren Hubert Jaeger, Lisa Bruns, Ginger Stratman, Christy Kidwell, Suzin Cunningham, Nicholas Piccone, Mordecai Klein, María Rodríguez Acuña, Srishti Arora, Amanda Clark, Ezekiel Fink, Cesia Garcia, Astrid George, Elizabeth Gray, C. M. Mahaffey, Maria McElheney, Elizabeth Reyes Ortíz, Sunny Saumya, Adele Wallace, Jenelle Watts, Daisy Zambrana, Douglas Denham, Erica Rivera, Ayoade Avworo, Parke Hedges, Corri Fancher, Rafik Abadier, Lisa Braud, Laura Cenatiempo, Amanda Elwood, Linda Esther Gray, Peter Gray, Kimberly Griffin, Hammad-ur-rehman Khan, Nadeen Kongquee, Susan LaTorraca, Tiffany Liles, J. M. Livingston, Marc Lozano, Amy Lupton, Tiffany Lyles, Deana Mardini, Susan Moss, K. Packer, Aakash Patel, Tina Russ, Brianna Scinicariello, Shannon Trull, Blair Warren, Fadi Chalhoub, Susan Angel, Sujeeta Dhakhwa, Ivy Gabon, Leticia Goodwin, Nandita Joshi Jones, Mark Joyce, Niketa Kamble, Brooke McFall, Rose Githiiyu, Leticia Robinson, Lauren A. Tomlinson, Emir Hadziavdic, Stephany Vega, James H. Greenwald, Jessica Achan, L Poyatos Ruiz, Mehwish Buksh, Omkar Chauhan, Elisee Derisseau, Faith Ferguson, Monika Grabowski, Larisa Gumerova, Miriam Hernandez, Kenna Martin, Krina K. Patel, Dibnain Nanda, José Garcı́a Pérez, Corey Ribeca, Elijah Rueda, Ana Sordi Guth, N. Modh Zaki, Ebony Green, Nina Mondoc, Robert Buynak, Stephanie Andree, Martha Brazinsky, L Fuller, Nikki Green, Hannade Ibrahim, Marilyn Idowu, Miranda Lee, Erica Lewis, Goldie Luna, Rachel McNeal, Alicia Owens, Consuelita Perez, Taryn Petty, Megan Smith, Patricia Volom, Angela Webb, Destiny Williams, Mark Yarosz, Nashwa Gabra, Nabil Andrawis, Amy Aziz, Magda Hanna, Josefina Manalo, Victoria Helow, William Davila, Sydney Crisp, Yvonne L. Douglas, Jenna Everett, Sarah Graham, Ellen Heard, Michelle Mackie, Suman Mayer, Lisa Moore, Stephanie Resurreccion, Jennifer Sidey, Michael C. Stephens, Mary Strickland, Dawn Van Camp, Stephanie Wilder, Anne Møller Witt, Jolenne Wolfer, L. Groben, Lindsey Aeschliman, Emily Audlehelm, Casey Fitz, Judi Greene, Emily Hippen, Michelle S. Johnson, Allan P. Latcham, Shekela Leggett, K. Link, J. E. J. Lovell, Kourtney Marlow, Cynthia Marske, Kelsey N. Maxwell, Charlotte Newsom-Henderson, Darcie Oelberg, Kathleen Ollinger, Rebecca Risius, Kylea Ryther, Alyssa Waddell, Tyler Zellerman, Martin Albornoz Santofimio, Stephen Plantholt, Morgan Beatty, Heather Blubaugh, Tina Bootz, Jeffrey A. Cole, Jasmine Conners, Vicki J. Coombs, Chloe Goddard, Carlos Ince, Gail Kiddy, Barbara Klimuszka, Frederick A. Kuhn, David Lowry, Patricia Previll, Stephanie Rioux, Jasmine Scott, B. A. Shepherd, Amy Urffer, Sarah L. Smiley, Gregg Lucksinger, Allison Alvord, J.D. Anderson, Courtney Block, Ashley S. M. Chan, John Delgado, K. R. Frost, Levi Gadbois, Danuel Hamlin, Sarah Johnson, Vivianna Juncal, Kary Kelly, Emily Kelly, Lilly Kelly, Avery Kerwin, Audrey Kuehl, Jaleh Ostovar, Ryan Rackley, George J. M. Rocha, L.B. Sandberg, Sarah Sheghewi, Tiffany M. Smith, Ben Taucher, Cecilia A. Vasquez, Francisca Villa Rodriguez, Jay Weisbart, Veronica Wescom, Keenan Williams, Jeffrey S. Overcash, Angela Anorve, Hunter Asmann, Gordon Bovee, Laura Castillo, Hanh Chu, Jordan Coslet, Allison Davis, Mary Dinan, Amanda Dubbula, Jacob Esparza, Ann Foster, Andrea Arnaiz García, Jessica Gonzales, Lizette Gonzalez, Pat Kappen, Allison Kornblatt, Brandon Lauderdale, Kia Lee, Sylvia Lindholm, Ashliegh Lindsay, Luis Llanos Gomez, Adrienna Marquez, Catherine Meza, Shandel Odom, Makenna Orel, Shanna Paselio, Samuel Penziner, Helen Pu, Kimberly Quillin, César E. Ramírez, Roxanna Ramirez, Mônica Santos Salgado, Marcy Shores, Raquel Taitingfong, Jennifer Tande, Van Tuiletufuga, Katrina Tyler, Linda Vega, Karla Zepeda, Corey L. Anderson, Nikki Carhill, Benjamin Clark, Lisa Dean, Naomi Devine, Sophia DiPeri, G. Espinal, Ronald E. Hawkins, Gabriela Irra, Angela Ledezma, Georgina Lopez-Wood, Micaela Luna, Wael Mansour, Tasha Marriott, Ashley Perez, James M. Ramsey, W. Jay Reedy, Hannah Spinks, Cecilia Tanori, David Tatelbaum, Rudy Vasquez, K.D. Vasquez, Jori Vigil, Isabel Worthen, Devin Yu, Jessica N. Zuniga, Patrick Dennis, L.D.L.A. Alvarado, Armand Cox, Victoria Cullaro, John Dunbar, Katherine Giorlando, London Hannan, Tyler Hastings, Geoff Hoskins, Emily Krambeck, J Laurent, Olga Michelle Martinez, Reggie Mister, Autumn Moss, Margaret Muli, Nicolette Quinn, Brittany Reed, Adam Robinson, Casey Saavedra, Caitlin Simon, Derek Smith, Dylan Touchet, Annie Wright,
Angiotensinogen is the most upstream precursor of the renin-angiotensin-aldosterone system, a key pathway in blood pressure (BP) regulation. Zilebesiran, an investigational RNA interference therapeutic, targets hepatic angiotensinogen synthesis.
American Medical Association
Shaun Martin, Heather K. Lamb, Corey Brady, Benjamin Lefkove, M Y Bonner, Paul R. Thompson, Penny E. Lovat, Jack L. Arbiser, A R Hawkins, Christopher P.F. Redfern,
Glucose regulated protein 78 (GRP78) functions as a sensor of endoplasmic reticulum (ER) stress. The aim of this study was to test the hypothesis that molecules that bind to GRP78 induce the unfolded protein response (UPR) and enhance cell death in combination with ER stress inducers.Differential scanning calorimetry (DSC), measurement of cell death by flow cytometry and the induction of ER stress markers using western blotting.Epigallocatechin gallate (EGCG), a flavonoid component of Green Tea Camellia ...
Tópico(s): Pharmacological Effects of Natural Compounds
2013 - Springer Nature | British Journal of Cancer
J W Dorigo-Zetsma, Jan T. M. van der Meer, M Tersmette, F. J. W. Ten Kate, P. M. E. Wertheim‐van Dillen, J. van der Noordaa,
... Medicine 112: 465– 466. Collier AC, Meyers JD, Corey L, Murphy VL, Roberts PL, Handsfield HH (1987): Cytomegalovirus infection in homosexual men: Relationship to sexual practices, antibody to human immunodeficiency virus, and cell-mediated immunity. American Journal of Medicine 82: 593– 601. Connolly GM, Hawkins D, Harcourt-Webstre JN, Parsons PA, Husain OA, ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
1996 - Wiley | Journal of Medical Virology
J.C. Corey, Richard H. Hawkins, R. F. Overman,
Abstract The gamma‐photoneutron method is unique among nuclear methods used to study water movement in soil because the heavy water ( 2 H 2 O) content of laboratory soil columns can be measured independently of bulk density of soil, soil texture, light water ( 1 H 2 O) content, and type of clay mineral. The method requires a radioactive source that emits gamma photons in excess of 2.23 Mev and a neutron detector. The neutron detector measures photoneutrons produced when the deuterium nuclei in the gamma ...
Tópico(s): Radioactivity and Radon Measurements
1970 - Wiley | Soil Science Society of America Journal
Linda A. Snyder, Krista Menard, Georges Habineza Ndikuyeze, Holly M. Nguyen, Anna C. Hughes, Lorraine Angelillo, Gerald Chu, Jenny Driscoll, Rebecca Hawkins, Eva Corey,
... Hughes, Lorraine Angelillo, Gerald Chu, Jenny Driscoll, Rebecca Hawkins, Eva Corey. Niraparib is active against prostate xenograft models that ...
Tópico(s): DNA Repair Mechanisms
2020 - American Association for Cancer Research | Cancer Research
Ganesh M. Shankar, Nina Lelic, Corey M. Gill, Aaron R. Thorner, Paul Van Hummelen, Jeffrey H. Wisoff, Jay S. Loeffler, Priscilla K. Brastianos, John H. Shin, Lawrence F. Borges, William E. Butler, David Zagzag, Rachel Brody, Ann-Christine Duhaime, Michael D. Taylor, Cynthia Hawkins, David N. Louis, Daniel P. Cahill, William T. Curry, Matthew Meyerson,
Intramedullary spinal cord neoplasms represent 2–4 % of central nervous system tumors, of which astrocytic gliomas represent 80 %. Patients presenting with spinal cord astrocytomas span the traditional pediatric and adult age divisions, having an overall age-distribution that is younger than cohorts with supratentorial gliomas. WHO grade I and II astrocytomas have better outcomes that are largely dependent on extent of surgical resection [10], whereas Grade III and IV astrocytomas are less amenable ...
Tópico(s): Sarcoma Diagnosis and Treatment
2015 - Springer Science+Business Media | Acta Neuropathologica
Erin Furr Stimming, Daniel O. Claassen, Elise Kayson, Jody Goldstein, Raja Mehanna, Hui Zhang, Grace Liang, Dietrich Haubenberger, Jamie Adams, Christopher A. Beck, Cheryl Chen, Martha Nance, Claudia Testa, Patricia Huffman, Amy M. Chesire, Frederick J. Marshall, Praveen Dayalu, Angela Stovall, Deborah A. Hall, Jacob Hawkins, Letty Ginsburg, Henry Moore, Tiago Mestre, Tanya Thompson, Natalie K. Connors, H. Diana Rosas, Allison M. Daley, Sandra K. Kostyk, Casey Mitchell, Amy Hellman, Sheryl Houston, Danielle Buchanan, Katherine E. McDonell, Stewart A. Factor, Elaine Sperin, Andrea Hurt, Joanne Wojcieszek, Mike Adurogbangba, Lynn A. Raymond, Jody Corey‐Bloom, Chase Snell, Courtney Blair, Victor Sung, Sophia Antonioli, Jacqueline Fung, Simon Laganiere, Luis Sierra, William Mallonee, Greg Suter, Danny Bega, Zsa Zsa Brown, Lawrence Elmer, Nancy Vollmar, Debra del Castillo, Yihan Lin, Kelly L. Andrzejewski, Patricia Weigel, Trevor Hawkins, Kendra Kirby, Cimmaron Retzik-Stahr, Lauren Seeberger, Rohit Dhall, Anja Rassmann, McKenzie Luxmore, B.L. Scott, Bisena Bulica, James T. Boyd, K. Chan, Nikolaus R. McFarland, Kyle Rizer, Patricia Conlon, Valerie Suski, Federico Rodríguez‐Porcel, Sandra R. Wilson, Christine Farrell, David J. Hunter, David Houghton, Sarah Seoane, Clare Gibbons, Philippe Rizek, Robin Kuprewicz, Steven Lo, Miroslav Cuturic, Vicki Segro, Kate Greenly, Fredy J. Revilla, Enrique Urrea‐Mendoza, Kevin J. Black, Thomas L. Davis, Natividad Stover, Andrew P. Duker, Jay Van Gerpen, Peter Hedera, William G. Ondo, Karen E. Anderson, Stephen Bradley, Ying Kuen Cheung, Samuel Frank,
Valbenazine is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor approved for treatment of tardive dyskinesia. To address the ongoing need for improved symptomatic treatments for individuals with Huntington's disease, valbenazine was evaluated for the treatment of chorea associated with Huntington's disease.KINECT-HD (NCT04102579) was a phase 3, randomised, double-blind, placebo-controlled trial, performed in 46 Huntington Study Group sites in the USA and Canada. The study included ...
Tópico(s): Mitochondrial Function and Pathology
2023 - Elsevier BV | The Lancet Neurology
Saul N. Faust, Richard Haynes, Christine E. Jones, Natalie Staplin, Elizabeth Whittaker, Thomas Jaki, Ed Juszczak, Enti Spata, Mandy Wan, Alasdair Bamford, Paul Dimitri, Adam Finn, John Furness, Athimalaipet V Ramanan, Chris Gale, Katrina Cathie, Simon B. Drysdale, Jolanta Bernatoniene, Clare Murray, Charles Christoph Roehr, Paul Fleming, Andrew Riordan, Srini Bandi, Deepthi Jyothish, Jennifer Evans, Marieke Emonts, Dominic F. Kelly, Nazima Pathan, Patrick Davies, Rosie Hague, Louisa Pollock, Malcolm G. Semple, Leon Peto, J. Kenneth Baillie, Maya H Buch, Katie Jeffery, Marian Knight, Wei Shen Lim, Alan Montgomery, Aparna Mukherjee, Andrew Mumford, Kathy Rowan, Guy Thwaites, Marion Mafham, Jonathan Emberson, Martin Landray, Peter Horby, Lucy C. Chappell, Jeremy Day, DV Dung, Jeremy Day, NN Quang, Prof Binh, Erlina Burhan, Bachti Alisjahbana, Janak Koirala, S Basnet, Evelyne Kestelyn, Buddha Basnyat, Pradip Gyanwali, RL Hamers, Peter Sandercock, Janet Darbyshire, David L. DeMets, Robert Fowler, David G. Lalloo, Mohammed Munavvar, Ian Roberts, Adilia Warris, Janet Wittes, A Craddock-Bamford, Janet Barton, Ahmet Başoğlu, Rosemary Brown, Wojciech Brudlo, Emmanuelle Denis, Lucy Fletcher, Sarah Howard, Sabrina Musini, K. Taylor, Guanglin Cui, Bob Goodenough, Andy J. King, M Lay, David R. Murray, W. Grant Stevens, Karl Wallendszus, Robert C. Welsh, Charles Crichton, Jane C. Davies, Raph Goldacre, Charlie Harper, F Knight, Miles A. Nunn, Hizni Salih, John J. Welch, Mark Campbell, Guilherme Pessoa-Amorim, Mohamed A. Zayed, Jonathan D. Wiles, GRANT P. BAGLEY, Scott J. Cameron, Sarah Chamberlain, Barbara Farrell, Hannah Freeman, Ann R. Kennedy, Anne Whitehouse, Sara Wilkinson, Caroline Wood, Christina Reith, K Davies, Heather Halls, Lisa Holland, Robert Truell, Kevin C. Wilson, Emma Lingwood, L. Howie, Michael P. Lunn, Penelope Rodgers, John Amuasi, Kathleen Baird, Ting Bao, Buddha Basnyat, Mustapha Bittaye, Joseph Bonney, Umberto D’Alessandro, Meghnath Dhimal, Pradip Gyanwali, RL Hamers, T Huyen, Abubacarr Jagne, Abhilasha Karkey, Evelyne Kestelyn, Oumou Maïga, E Matey, Behzad Nadjm, Jeremy Nel, Suman Pant, Khairunnisa Puspatriani, Mutia Rahardjani, S Raijal, Helen Rees, Atika Rimainar, Charles W.M. Roberts, Anna Rocca, Sailendra Kumar Duwal Shrestha, Effua Usuf, C. Vidaillic, Fitria Wulandari, Amit Alexander, M. R. Amezaga, Charlotte Armah, Asma Asghar, Paula Aubrey, Kerry Barker-Williams, Amanda Barnard, John R. Bartholomew, Dawn Beaumont-Jewell, Simon Beddows, J. Beety, Chris Birch, Peter Boyle, Morwenna Brend, Matthew Brookes, Claire Callens, Danielle Campbell, Helen Campbell, Hugo Ten Cate, Emma S. Chambers, K Chapman, Antoinette B. Coe, Joanne Collins, Sarah Crawshaw, Sandeep R. Das, Anthony De Soyza, Erika Denton, Pamela Dicks, Mary Dolman, Kate Donaldson, Lucy Dowden, Shawn Dowling, Charles G. Drake, Hayley Duckles-Leech, Helen Duffy, Lee Gerdes, Kristen Gibbons, Lorena Almeida Gill, Kimberly Gilmour, Joanne Goodwin, James E. Graham, Christopher Green, Claire Hall, Alistair S. Hall, Kate Hampshire, Jane Hanson, T Harman, Helen Harper, Susan T.L. Harrison, James W. Hicks, Helen Hodgson, Michael Hough, Susan Jackson, Graham Johnson, Jodie Kirk, Nicholas R. Lemoine, Chris Levett, S Lock, Teresa Lockett, M Logan, Kaatje Lomme, Jing‐chao Luo, Nigel A.J. McMillan, Helen Membrey, Nhlanhla Mguni, Jane Minton, H Monaghan, Shawn N. Murphy, Natasha Muzengi, Madiha Naz, Ian Nickson, Miranda Odam, Udeme Ohia, Eleanor OKell, Antonio Oliver, Karen Pearson, Kirsty Pine, Richard J. Pleass, David A. Porter, Linda Porter, Alison Potter, Vanessa Poustie, Steven Pratt, Anna Price, Alicia Priest, Anthony Rodgers, C Rook, Pablo Ryan, S Sam, Phoebe Sharratt, James K. Sheffield, Justine Shenton, K Shirley, Timothy Skinner, Herbert B. Slade, Mihaela Sutu, Judy Taylor, E Thomas, Heather Tinkler, Alison Unsworth, R. Usher, William van’t Hoff, S E Walker, James Walters, E Walton, Jenny Warmington, Emma Wayman, Patricia Williams, John Williamson, Deborah A. Williamson, Fiona Yelnoorkar, Marian Knight, Kenneth Hodson, Sue Pavord, Catherine Williamson, Louise Bowman, Fei Chen, Robert W. Clarke, Michelle Goonasekara, William G. Herrington, P. G. Judge, S Ng, David Preiss, Christina Reith, Emily Sammons, Dandan Zhu, C Arkley, Paul Bowker, Johanna Bruce, Victoria Byrne-Watts, G Chapman, Grahame J. Coleman, Tom Denwood, J.D. Gray, David A Harrison, Nancy Mather, Heather Pinches, A.R. Rees, Stephanie Rees, Gail Turner, Obbina Abani, Amr E. Abbas, Fatima Abbas, Jonathan R. Abbas, Kaja Abbas, Mustafa Abbas, Sadia Abbasi,
BackgroundPaediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children (MIS-C) emerged in April, 2020. The paediatric comparisons within the RECOVERY trial aimed to assess the effect of intravenous immunoglobulin or corticosteroids compared with usual care on duration of hospital stay for children with PIMS-TS and to compare tocilizumab (anti-IL-6 receptor monoclonal antibody) or anakinra (anti-IL-1 receptor ...
Elsevier BV
Janaíre Hawkins, J. Corey Williams, Noel Bravo, Satyani K. L. McPherson, Travis Spencer, Dominique Charlot‐Swilley, Celene E. Domitrovich, Matthew G. Biel,
Tópico(s): Early Childhood Education and Development
2024 - Springer Science+Business Media | Mindfulness