Milea J. M. Timbergen, Anne‐Rose W. Schut, Dirk J. Grünhagen, Stefan Sleijfer, Cornelis Verhoef,
BackgroundThis study evaluates the results of the active surveillance (AS) approach in adult patients with desmoid-type fibromatosis (DTF) because AS is advocated as a front-line approach for DTF in the European consensus guidelines.MethodsA systematic literature search was conducted (December 19th, 2019, updated on April 14th, 2020). Studies describing the outcomes of the AS approach were included. The PRISMA guidelines were used.ResultsTwenty-five articles were included for data retrieval. Forty- ...
Tópico(s): Sarcoma Diagnosis and Treatment
2020 - Elsevier BV | European Journal of Cancer
Johannes J.M. Kwakman, Geraldine R. Vink, J.H.M.J. Vestjens, Laurens V. Beerepoot, Jan Willem de Groot, Slinger Jansen, Frans L. Opdam, Henk Boot, G.J. Creemers, Johan M. van Rooijen, Maartje Los, A. J. E. Vulink, Heidi Schut, E. van Meerten, Arnold Baars, Paul Hamberg, Ellen Kapiteijn, Dirkje W. Sommeijer, Cornelis J.A. Punt, Miriam Koopman,
The RECOURSE trial showed clinical efficacy for trifluridine/tipiracil for refractory metastatic colorectal cancer patients. We assessed the feasibility and effectiveness of trifluridine/tipiracil in daily clinical practice in The Netherlands. Medical records of patients from 17 centers treated in the trifluridine/tipiracil compassionate use program were reviewed and checked for RECOURSE eligibility criteria. Baseline characteristics, safety, and survival times were compared, and prespecified baseline ...
Tópico(s): Colorectal Cancer Surgical Treatments
2017 - Springer Science+Business Media | International Journal of Clinical Oncology
Jurgen Cornelis, Ansam Barakat, Jack Dekker, Tessy Schut, S Brook M Berk, Hans Nusselder, Nikander Ruhl, Jeroen Zoeteman, Rien Van, Aartjan T.F. Beekman, Matthijs Blankers,
Hospitalization is a common method to intensify care for patients experiencing a psychiatric crisis. A short-term, specialised, out-patient crisis intervention by a Crisis Resolution Team (CRT) in the Netherlands, called Intensive Home Treatment (IHT), is a viable intervention which may help reduce hospital admission days. However, research on the (cost-)effectiveness of alternatives to hospitalisation such as IHT are scarce. In the study presented in this protocol, IHT will be compared to care-as- ...
Tópico(s): Schizophrenia research and treatment
2018 - BioMed Central | BMC Psychiatry
D. Scorticati, A. Illiberi, T.C. Bor, S.W.H. Eijt, H. Schut, G.R.B.E. Römer, Michel Klein Gunnewiek, Aufried Lenferink, B. Kniknie, R. Mary Joy, Maarten Dörenkämper, D. Lange, Cornelis Otto, D. M. Borsa, W.J. Soppe, A.J. Huis in ‘t Veld,
Industrial-grade Al:ZnO thin films, were annealed by UV picosecond laser irradiation in argon atmosphere. A remarkable increase of both the carrier density and electron mobility was measured, while the optical properties in the 400–1000 nm range did not change significantly. We studied the microstructure of the films, in order to explain the observed macroscopical changes upon ultra-short pulsed laser annealing. The effects of the ps-laser irradiation are shown to be attributed to the formation ...
Tópico(s): Electronic and Structural Properties of Oxides
2015 - Elsevier BV | Acta Materialia
Anne‐Rose W. Schut, Milea J. M. Timbergen, Danique L. M. van Broekhoven, Thijs van Dalen, Winan J. van Houdt, Johannes J. Bonenkamp, Stefan Sleijfer, Dirk J. Grünhagen, Cornelis Verhoef,
Objective: To assess tumor behavior and the efficacy of active surveillance (AS) in patients with desmoid-type fibromatosis (DTF). Summary of Background Data: AS is recommended as initial management for DTF patients. Prospective data regarding the results of AS are lacking. Methods: In this multicenter prospective cohort study (NTR4714), adult patients with non-intraabdominal DTF were followed during an initial AS approach for 3 years. Tumor behavior was evaluated according to Response Evaluation Criteria ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
2022 - Lippincott Williams & Wilkins | Annals of Surgery
Anne‐Rose W. Schut, Milea J. M. Timbergen, Emma Lidington, Dirk J. Grünhagen, Winette T.A. van der Graaf, Stefan Sleijfer, Winan J. van Houdt, Johannes J. Bonenkamp, Eugenie Younger, Alison Dunlop, Robin L. Jones, Cornelis Verhoef, Spyridon Gennatas, Olga Husson,
Sporadic desmoid-type fibromatosis (DTF) is a rare soft tissue tumour with an unpredictable clinical course. These tumours are incapable of metastasising, but their local aggressive tumour growth and tendency to recur locally can result in a substantial symptom burden. Measuring the impact of DTF on health-related quality of life (HRQoL) can be challenging due to the variable clinical presentation of the disease. Therefore, a HRQoL instrument assessing DTF-specific issues is needed. The QUALIFIED ...
Tópico(s): Cancer and Skin Lesions
2021 - Multidisciplinary Digital Publishing Institute | Cancers
Tara M. Mackay, F. Jasmijn Smits, Anouk E.J. Latenstein, Auke Bogte, Bert A. Bonsing, Hayley Bos, K. Bosscha, Lodewijk A.A. Brosens, Lieke Hol, Olivier R. Busch, G.J. Creemers, Wouter L. Curvers, Marcel den Dulk, Susan van Dieren, Lydi M.J.W. van Driel, Sebastiaan Festen, Erwin J. M. van Geenen, Lydia G. van der Geest, Derk Jan A. de Groot, Jan Willem B. de Groot, Nadia Haj Mohammad, Brigitte C.M. Haberkorn, Joyce T. Haver, Erwin van der Harst, Gerrit J. Hemmink, Ignace H. J. T. de Hingh, Chantal Hoge, Marjolein Y.V. Homs, N. C. van Huijgevoort, Michael A. Jacobs, Emile D. Kerver, Mike S.L. Liem, Maartje Los, Hans Lubbinge, Saskia Luelmo, Vincent E. de Meijer, Leonie J. Mekenkamp, I. Quintus Molenaar, Martijn G.H. van Oijen, Gijs A. Patijn, Rutger Quispel, L. Bengt van Rijssen, Tessa E H Römkens, Hjalmar C. van Santvoort, Jennifer M. J. Schreinemakers, Heidi Schut, Tom Seerden, Martijn W.J. Stommel, Albert J. ten Tije, Niels G. Venneman, Robert C. Verdonk, Joanne Verheij, Frederike G.I. van Vilsteren, Judith de Vos‐Geelen, Annelie Vulink, Caroline Wientjes, Fennie Wit, Frank J. Wessels, Babs M. Zonderhuis, Cornelis H. van Werkhoven, Jeanin E. van Hooft, Casper H.J. van Eijck, Johanna W. Wilmink, Hanneke W.M. van Laarhoven, Marc G. Besselink,
Abstract Background Pancreatic cancer has a very poor prognosis. Best practices for the use of chemotherapy, enzyme replacement therapy, and biliary drainage have been identified but their implementation in daily clinical practice is often suboptimal. We hypothesized that a nationwide program to enhance implementation of these best practices in pancreatic cancer care would improve survival and quality of life. Methods/design PACAP-1 is a nationwide multicenter stepped-wedge cluster randomized controlled ...
Tópico(s): Gallbladder and Bile Duct Disorders
2020 - Springer Science+Business Media | Trials
Anne‐Rose W. Schut, Anne L. M. Vriends, Andrea Sacchetti, Milea J. M. Timbergen, Benjamin A. Alman, Mushriq Al‐Jazrawe, Dirk J. Grünhagen, Cornelis Verhoef, Stefan Sleijfer, Erik A.C. Wiemer,
Desmoid-type fibromatosis (DTF) is a rare, soft tissue tumour. Sorafenib, a multikinase inhibitor, has demonstrated antitumour efficacy in DTF patients. Little is known about the underlying molecular mechanisms, which are crucial to know to further optimize systemic treatments. Here we investigated the molecular effects of sorafenib exposure on DTF and stromal cells, with an emphasis on cell death mechanisms.DTF primary cell cultures, with known CTNNB1 status, and primary stromal cell cultures, derived ...
Tópico(s): Tumors and Oncological Cases
2022 - Elsevier BV | European Journal of Surgical Oncology
Anne‐Rose W. Schut, Emma Lidington, Milea J. M. Timbergen, Eugenie Younger, Winette T.A. van der Graaf, Winan J. van Houdt, Johannes J. Bonenkamp, Robin L. Jones, Dirk J. Grünhagen, Stefan Sleijfer, Cornelis Verhoef, Spyridon Gennatas, Olga Husson,
Desmoid-type fibromatosis (DTF) is a rare, soft-tissue tumour. These tumours do not metastasize, but their local aggressive tumour growth and unpredictable behaviour can have a significant impact on health-related quality of life (HRQoL). Little is known about which DTF patients are particularly affected by an impaired HRQoL. The objectives of this study were to assess HRQoL among different groups of DTF patients and to investigate which socio-demographic and clinical characteristics were associated ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
2022 - Multidisciplinary Digital Publishing Institute | Cancers
Anne‐Rose W. Schut, Emma Lidington, Milea J. M. Timbergen, Eugenie Younger, Winette T.A. van der Graaf, Winan J. van Houdt, Johannes J. Bonenkamp, Robin L. Jones, Dirk J. Grünhagen, Stefan Sleijfer, Cornelis Verhoef, Spyridon Gennatas, Olga Husson,
Sporadic desmoid-type fibromatosis (DTF) is a rare, non-metastasising soft-tissue tumour. Patients can experience a variety of disease-specific issues related to the unpredictable clinical course and aggressiveness of DTF, which negatively impacts health-related quality of life (HRQoL). These DTF-specific issues are not captured by generic HRQoL tools. A 102-item provisional DTF-specific HRQoL tool, the DTF-QoL, was previously developed. The aim of this study was to pre-test the psychometric properties ...
Tópico(s): Cancer and Skin Lesions
2022 - Multidisciplinary Digital Publishing Institute | Cancers
Anne‐Rose W. Schut, Milea J. M. Timbergen, Kazem Nasserinejad, Thijs van Dalen, Winan J. van Houdt, Johannes J. Bonenkamp, Stefan Sleijfer, Dirk J. Grünhagen, Cornelis Verhoef, Olga Husson,
To examine the impact of an active surveillance (AS) approach on the health-related quality of life (HRQoL) of patients with desmoid-type fibromatosis (DTF).AS is recommended as initial approach in DTF patients. AS might however negatively affect HRQoL due to physical symptoms or stress and anxiety.In a prospective observational study, the GRAFITI trial (NTR4714), DTF patients were followed during an initial AS approach for 3 years. HRQoL was assessed by the EORTC QLQ-C30 at baseline, 6, 12 and 24-month ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
2023 - Lippincott Williams & Wilkins | Annals of Surgery
Marinde J. G. Bond, Karen Bolhuis, O. J. L. Loosveld, Jan Willem B. de Groot, Helga J. Droogendijk, Helgi H. Helgason, Mathijs P. Hendriks, Joost M. Klaase, Geert Kazemier, Mike S.L. Liem, Arjen M. Rijken, Cornelis Verhoef, Johannes H.W. de Wilt, Koert P. de Jong, Michael F. Gerhards, Martinus J. van Amerongen, Marc R. Engelbrecht, Krijn P. van Lienden, I. Quintus Molenaar, Bart de Valk, Brigitte C.M. Haberkorn, Emile D. Kerver, Frans Erdkamp, Robbert J. van Alphen, Daniëlle Mathijssen‐van Stein, Aysun Komurcu, Marta López‐Yurda, Rutger‐Jan Swijnenburg, Cornelis J.A. Punt, Thomas van Gulik, Joost Huiskens, Harm van Tinteren, Cornelis H.C. Dejong, Dirk J. Grünhagen, Gijs A. Patijn, Theo J. M. Ruers, T. Chapelle, John J. Hermans, Wouter K. G. Leclercq, Liselot Valkenburg‐van Iersel, Cecile Grootscholten, Joyce M. van Dodewaard-de Jong, Jeroen Vincent, Danny Houtsma, Maartje Los, Marien den Boer, Marija Trajkovic-Vidakovic, Theo van Voorthuizen, Miriam Koopman, Johanneke H.M.J.V. Vestjens, Hans Torrenga, Leonie J. Mekenkamp, G.J. Veldhuis, Marco B. Polée, Serge E. Dohmen, Heidi Schut, Annelie J.E. Vulink, Henk K. van Halteren, Jamal Oulad Hadj, Pieter-Paul J.B.M. Schiphorst, Ronald Hoekstra,
Patients with initially unresectable colorectal cancer liver metastases might qualify for local treatment with curative intent after reducing the tumour size by induction systemic treatment. We aimed to compare the currently most active induction regimens.In this open-label, multicentre, randomised, phase 3 study (CAIRO5), patients aged 18 years or older with histologically confirmed colorectal cancer, known RAS/BRAFV600E mutation status, WHO performance status of 0-1, and initially unresectable ...
Tópico(s): Cancer Genomics and Diagnostics
2023 - Elsevier BV | The Lancet Oncology
... Descheemaeker, Gerrie van de Ven, Antonius G.T. Schut, Mark van Wijk, James Hammond, Zvi Hochman, Godfrey ... 1111/j.1468-0297.2006.01117.xClemens Lutz, Cornelis Praagman, Luu Thanh Duc Hai Rice market integration ...
Tópico(s): Agriculture, Land Use, Rural Development
1992 - University of Chicago Press | Economic Development and Cultural Change
Dave E. W. van der Kruijssen, Sjoerd G. Elias, Geraldine R. Vink, Karlijn L. van Rooijen, Jorine ‘t Lam-Boer, Linda Mol, Cornelis J.A. Punt, Johannes H.W. de Wilt, Miriam Koopman, Gijs J.D. van Acker, Rahim Altaf, Kees van Arkel, Coen I.M. Baeten, Sandra D. Bakker, Frank C. den Boer, Marien O. den Boer, K. Bosscha, Edwin A. van Breugel, Rebecca P. M. Brosens, Huib A. Cense, Esther C. J. Consten, Geert‐Jan Creemers, Hester van Cruijsen, Wendy M. van der Deure, Joyce M. van Dodewaard, Anne-Lene G. Fromm, A. J. Gelderblom, Michael F. Gerhards, Marie-José de Gier, Eelco J. R. de Graaf, Wilhelmina M. U. van Grevenstein, Jan Willem B. de Groot, Brigitte C.M. Haberkorn, Jamal Oulad Hadj, Paul Hamberg, Erwin van der Harst, Helgi H. Helgason, Mathijs P. Hendriks, Daniël A. Hess, Ignace H. J. T. de Hingh, Ronald Hoekstra, Joost A.B. van der Hoeven, M.J. van Hoogstraten, Henrik Jakobsen, Felix E. de Jongh, Emile D. Kerver, Monica L Kjaer, Bart C. Kuenen, Philomeen Kuijer, Sophie A. Kurk, Wouter K. G. Leclercq, Lobke L. van Leeuwen-Snoeks, Jeroen W. A. Leijtens, Gábor Liposits, O. J. L. Loosveld, Martijn F. Lutke Holzik, Peter Nieboer, Jesper Dan Nielsen, Koen Peeters, Lone N. Petersen, Apollo Pronk, Bareld B. Pultrum, Koen Reijnders, J.M.G.H. van Riel, Ron C. Rietbroek, George P. van der Schelling, Wilhelmina H. Schreurs, Nis H. Schlesinger, Heidi Schut, Michael Seiersen, Lieke H. J. Simkens, Dirkje W. Sommeijer, Pieter J. Tanis, Mehmet Temizkan, Marc W. A. van Tilburg, Marija Trajkovic, Anthony W. H. van de Ven, Henk M.W. Verheul, Mareille Verseveld, Jeroen Vincent, Wouter J. Vles, F. Jeroen Vogelaar, Aad I. de Vos, Allert H. Vos, Ronald J.C.L.M. Vuylsteke, Wim Bleeker, Dareczka Wasowicz-Kemps, Johannes A. Wegdam, Henderik L. van Westreenen, Louise M. de Widt-Levert, Agnès J. van de Wouw, Mette Yilmaz, Peter van Duijvendijk,
Importance The role of primary tumor resection (PTR) in synchronous patients with metastatic colorectal cancer (mCRC) who had unresectable metastases and few or absent symptoms of their primary tumor is unclear. Studying subgroups with low postoperative mortality may identify patients who potentially benefit from PTR. Objective To determine the difference in 60-day mortality between patients randomized to systemic treatment only vs PTR followed by systemic treatment, and to explore risk factors associated with ...
Tópico(s): Gastric Cancer Management and Outcomes
2021 - American Medical Association | JAMA Surgery
Subodh Verma, Deepak L. Bhatt, Philippe Gabríel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Nitish K. Dhingra, Steven B. Ketchum, Rebecca A. Juliano, Lixia Jiao, Ralph T. Doyle, Craig Granowitz, C. Michael Gibson, Duane S. Pinto, Robert P. Giugliano, Matthew J. Budoff, R. Preston Mason, Jean‐Claude Tardif, Christie M. Ballantyne, Deepak L. Bhatt, Christie M. Ballantyne, Eliot A. Brinton, Terry A. Jacobson, Michael Miller, Philippe Gabríel Steg, Jean‐Claude Tardif, F M A C Martens, Astrid Schut, Brian Olshansky, Mina K. Chung, Al Hallstrom, Lesly A. Pearce, Cyrus R. Mehta, Rajat Mukherjee, C. Michael Gibson, Anjan Chakrabarti, Eli V. Gelfand, Robert P. Giugliano, Megan Carroll Leary, Duane S. Pinto, Yuri B. Pride, Steven Ketchum, Ramakrishna Bhavanthula, G. H. Chester, Christina Copland, Katelyn Diffin, Ralph T. Doyle, K. H. Erz, Alex Giaquinto, Paula Glanton, Angela Granger, Craig Granowitz, Richard H. Iroudayassamy, Lixia Jiao, Rebecca A. Juliano, James Jin, Dimitry Klevak, Hardik Panchal, Robert Wang, Shin-Ru Wang, G Abate, Peggy J. Berry, Rene A. Braeckman, Declan Doogan, Anne Elson, Amy HauptmannBaker, Isabel Lamela, Catherine A Lubeck, Mehar S. Manku, Sabina A. Murphy, Monica Sanford, William G. Stirtan, Paresh N. Soni, Arnaud Bastien, Demetria Foster, Evangelito Gascon, Judith Johnson, Lasbert Latona, Gang Liu, Sandra M. Palleja, N. San-Juan, JiaHao Shi, William Stager, Mukund Venkatakrishnan, Ahmed YoussefAgha, Julie Zhu, Leela Aertker, S. Ankolekar, Lisa Goldberg, Natasa Rajicic, Jianfen Shu, Heng Zou, Magdy S. Mikhail, Gamil Dawood, N. MATHEW KOSHY, Sandip Mukherjee, Rafik Abadier, Andrea Lawless, William P. McGuinn, Howard Weintraub, Kathryn Rohr, Edmund Claxton, Robert Weiss, Terry D. Klein, Mani Nallasivan, Stephen T. Crowley, Marilyn King, Anthony D. Alfieri, David Fitz-Patrick, Irving K. Loh, Nolan Mayer, Rakesh Prashad, S. Lederman, Debra F. Weinstein, Harold Bays, Keith Chu, Alireza Maghsoudi, P. D. Thompson, Jeff Carstens, Anna Chang, Ken Cohen, Julius Dean, Howard Ellison, Bernard Erickson, Enrique A. Flores, Daniel W. Gottlieb, Paul Grena, John R. Guyton, Peter H. Jones, John Joseph, Norman E. Lepor, Sam Lerman, Robert D. Matheney, Theodore R. Pacheco, Michael B. Russo, John Rubino, Edward Pereira, Albert A. Seals, Eduardo Viera, Alan D. Steljes, Jason D. Thompson, Shaival Kapadia, Michael McIvor, Jorge E. Salazar, Jose O. Santiago, Ralph Vicari, Martin R. Berk, William A. Kaye, Marcus E. McKenzie, David Podlecki, Brian D. Snyder, Stephen Nash, David M. Herrington, Wallace Johnson, Joseph R. Lee, Ronald Blonder, Alpa M. Patel, Ramón Castelló, Susan Greco, Larry S. Dean, Venkatesh Nadar, Mark A. Nathan, Ranganatha P. Potu, Robert Sangrigoli, Richard W. Smalling, Mitchell Davis, Robert Braastad, James W. McCriskin, Kunal Bodiwala, Joe Hargrove, Mark Graves, George Emlein, Raegan W. Durant, James W. Clower, Rohit Arora, Narendra Singh, Lisa W. Martin, W. Herbert Haught, Marc P. Litt, Michael D. Klein, Peter Hoagland, Michael Goldstein, Marco Mazzella, Daniel H. Dunker, Brian H. Kahn, Carlos S. Ince, Frank McGrew, Lee Jc, David Pan, Salman Khan, Uri Elkayam, Wasim Deeb, Anne C. Goldberg, Christopher Brown, Wayne Leimbach, Thomas S. Backer, David Sutton, Matthew J. Budoff, Joel Gellman, Anu R. George, Alan S. Hoffman, Mark Kates, Kishlay Anand, Robert A. Bear, B Cavanaugh, Ramon G. Reyes, Rodolfo Sotolongo, Kenneth Sabatino, Kevin Gallagher, Ehab Sorial, Chris Geohas, Kathleen Magness, Bernard Grunstra, Frederik A. Martin, William S. Knapp, Mel E. Lucas, John J. Champlin, Jason Demattia, Patrick H. Peters, Judith Kirstein, William J. Randall, Cezar Staniloae, Jennifer G. Robinson, A. Adler, Christopher Case, Andrew J. Kaplan, Gregory F. Lakin, Krishan K. Goyle, Michael J. DiGiovanna, Chester Fisher, Michael Lillestol, Michael R. Robinson, Robert G. Perry, Lawrence S. Levinson, Brian G. Everhart, Robert D. Madder, Earl F. Martin, Earl E. Martin, Imtiaz Alam, Jose Mari L. Elacion, Robina Poonawala, Taddese T. Desta, Jerome A. Robinson, Gilbert J. Martinez, Jakkidi Reddy, Jeffrey D. Wayne, Samuel Mujica Trenche, Westbrook I. Kaplan, Rubin H. Saavedra, Michael D. DiGregorio, Barry Bertolet, Neil J. Fraser, Terence T. Hart, Ronald J. Graf, David Jasper, Michael Dunn, Dan Streja, David J. Strobl, Nan Jiang, Vicki Kalen, Richard Mascolo, Mercedes B. Samson, Michael C. Stephens, Bret M. Bellard, Mario Juarez, Patrick J. McCarthy, John Checton, Michael Stillabower, Edward Goldenberg, Amin H. Karim, Naseem Jaffrani, Robert C. Touchon, Erich R. Fruehling, Clayton J. Friesen, Pradipta Chaudhuri, Frank H. Morris, Robert Broker, Rajesh Patel, Susan Hole, R Miller, Francisco G. Miranda, Sadia Dar, S Gentry, Paul Hermany, Charles B. Treasure, Miguel E. Trevino, R Villacorta Acosta, Anthony J. Japour, Samuel J. Durr, Thomas J. Wang, Om P Ganda, Perry Krichmar, James L. Arter, Douglas Jacoby, Michael Schwartz, Amer Al‐Karadsheh,
Despite advances in surgery and pharmacotherapy, there remains significant residual ischemic risk after coronary artery bypass grafting surgery. In REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl-Intervention Trial), a multicenter, placebo-controlled, double-blind trial, statin-treated patients with controlled low-density lipoprotein cholesterol and mild to moderate hypertriglyceridemia were randomized to 4 g daily of icosapent ethyl or placebo. They experienced a 25% reduction ...
Lippincott Williams & Wilkins
Bernd Kasper, Elizabeth H. Baldini, Sylvie Bonvalot, Dario Callegaro, Kenneth Cardona, Chiara Colombo, Nadège Corradini, Aimeé M. Crago, Angelo Paolo Dei Tos, Palma Dileo, Eldad Elnekave, Joseph P. Erinjeri, Fariba Navid, Jeffrey M. Farma, Andrea Ferrari, Marco Fiore, Rebecca Gladdy, Mrinal M. Gounder, Rick L. Haas, Olga Husson, Jean‐Emmanuel Kurtz, Alex J. Lazar, Daniel Orbach, Nicolas Penel, R. Ratan, Chandrajit P. Raut, Christina L. Roland, Ann-Rose W. Schut, Monika Sparber‐Sauer, D. Strauß, Winette T.A. van der Graaf, Marco Vitellaro, Aaron R. Weiss, Alessandro Gronchi, Benjamin A. Alman, Steven Attia, Jyoti Bajpai, Giacomo Giulio Baldi, Livia Prudente Barbieri, Christina Baumgarten, Charlotte Benson, Jean‐Yves Blay, Kjetil Boye, Bernadette Brennan, Andre Domenico Campanacci, Paolo G. Casali, Michela Casanova, Tom Wie-Wu Chen, Lorenzo D’Ambrosio, Chaves Maria Carolina De Menezes, Armelle Dufresne, Hans Roland Dürr, Anna Maria Frezza, David Gyorki, Sam Hackett, Florian Haller, Audrey Hélaine, Peter Hohenberger, Toni Ibrahim, Shintaro Iwata, Robin L. Jones, Akira Kawai, Mohamed Kelany, David G. Kirsch, Andreas Leithner, Andrea MacNeill, Christina Messiou, Robert G. Maki, Carlo Morosi, Andrea Napolitano, Yoshihiro Nishida, Elena Palassini, Shreyaskumar Patel, Giulia Personeni, Raphael E. Pollock, Emanuele Rausa, Evelyne Roets, Enrica Rossi, Piotr Rutkowski, D. Salvatore, Claudia Sangalli, Marta Sbaraglia, Philip Michael Smith, Silvia Stacchiotti, William D. Tap, Gabriel Tinoco, Dimitri Tzanis, Michiel A. J. van de Sande, Kim van der Zande, Winan J. van Houdt, Cornelis Verhoef, Andrew J. Wagner, Eva Wardelmann, Jeanne Whiting,
Desmoid tumor (DT) is a rare and locally aggressive monoclonal, fibroblastic proliferation characterized by a variable and often unpredictable clinical course. Previously, surgery was the standard primary treatment modality; however, within the past decade, a paradigm shift toward less-invasive management has been introduced and an effort to harmonize the strategy among clinicians has been made. To update the 2020 global evidence-based consensus guideline on the management of patients with DT, the ...
Tópico(s): Bone Tumor Diagnosis and Treatments
2024 - American Medical Association | JAMA Oncology
Anne‐Rose W. Schut, Leanne E. de Bruin, Belle H. de Rooij, Emma Lidington, Milea J. M. Timbergen, Winette T.A. van der Graaf, Winan J. van Houdt, Johannes J. Bonenkamp, Robin L. Jones, Dirk J. Grünhagen, Stefan Sleijfer, Spyridon Gennatas, Cornelis Verhoef, Olga Husson,
Abstract Background Desmoid‐type fibromatosis (DTF) has a highly variable clinical course with varying intensity of symptoms. The objectives of this study were to identify subgroups of DTF patients based on physical symptom burden and to compare symptom burden subgroups on health‐related quality of life (HRQoL) and healthcare use (univariate and multivariate). Methods Desmoid‐type fibromatosis patients from the United Kingdom and the Netherlands received cross‐sectional questionnaires on HRQoL (EORTC ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
2023 - Wiley | Cancer Medicine
Douwe J. Spaanderman, Martijn P. A. Starmans, Gonnie C. M. van Erp, David Hanff, Judith H. Sluijter, Anne‐Rose W. Schut, Geert J.L.H. van Leenders, Cornelis Verhoef, Dirk J. Grünhagen, Wiro J. Niessen, Jacob J. Visser, Stefan Klein,
Abstract Background Segmentations are crucial in medical imaging for morphological, volumetric, and radiomics biomarkers. Manual segmentation is accurate but not feasible in clinical workflow, while automatic segmentation generally performs sub-par. Purpose To develop a minimally interactive deep learning-based segmentation method for soft-tissue tumors (STTs) on CT and MRI. Material and methods The interactive method requires the user to click six points near the tumor’s extreme boundaries in the ...
Tópico(s): Bone Tumor Diagnosis and Treatments
2024 - Springer Science+Business Media | European Radiology
Dave E. W. van der Kruijssen, Sjoerd G. Elias, Peter M. van de Ven, Karlijn L. van Rooijen, Jorine ‘t Lam-Boer, Linda Mol, Cornelis J.A. Punt, Dirkje W. Sommeijer, Pieter J. Tanis, Jørn Dalsgaard Nielsen, M.K. Yilmaz, J.M.G.H. van Riel, D.K. Wasowiz-Kemps, O. J. L. Loosveld, George P. van der Schelling, J.W.B. de Groot, Henderik L. van Westreenen, Henrik Jakobsen, A.L. Fromm, Paul Hamberg, M. Verseveld, Claudia Jaensch, Gábor Liposits, Peter van Duijvendijk, Jamal Oulad Hadj, Joost A.B. van der Hoeven, Marija Trajkovic, Johannes H.W. de Wilt, M. Koopman, Jeroen Vincent, Johannes A. Wegdam, Brigitte C.M. Haberkorn, Erwin van der Harst, Mathijs P. Hendriks, Wilhelmina H. Schreurs, Huib A. Cense, Ron C. Rietbroek, Marie-José de Gier, Edwin A. van Breugel, Aad I. de Vos, Rebecca P. M. Brosens, Pascal G. Doornebosch, Felix E. de Jongh, Wouter J. Vles, Marien O. den Boer, Jeroen W. A. Leijtens, A. J. Gelderblom, Koen Peeters, Bart C. Kuenen, Bareld B. Pultrum, Joyce M. van Dodewaard-de Jong, Esther C. J. Consten, A.J. Yes van de Wouw, Joop Konsten, Ronald Hoekstra, Martijn F. Lutke Holzik, Allert H. Vos, M.J. van Hoogstraten, Nis H. Schlesinger, Geert-Jan Creemers, Ignace H. J. T. de Hingh, Monica L Kjaer, Lone N. Petersen, Michael Seiersen, Rahim Altaf, Hester van Cruijsen, Daniël A. Hess, Lobke L. van Leeuwen-Snoeks, Apollo Pronk, Coen I.M. Baeten, Wendy M. van der Deure, K. Bosscha, Heidi Schut, Wouter K. G. Leclercq, Lieke H. J. Simkens, Koen Reijnders, Kees van Arkel, W.M.U. Helma van Grevenstein, Anthony W. H. van de Ven, Ronald J.C.L.M. Vuylsteke, Philomeen Kuijer, Sandra D. Bakker, Hauwy Goei, Helgi H. Helgason, Gijs J.D. van Acker, Mehmet Temizkan, Marc W. A. van Tilburg, Michael F. Gerhards, Emile D. Kerver, Elske C. Gootjes, Peter Nieboer, Wim Bleeker, Gitta Bleeker,
Upfront primary tumor resection (PTR) has been associated with longer overall survival (OS) in patients with synchronous unresectable metastatic colorectal cancer (mCRC) in retrospective analyses. The aim of the CAIRO4 study was to investigate whether the addition of upfront PTR to systemic therapy resulted in a survival benefit in patients with synchronous mCRC without severe symptoms of their primary tumor.
Tópico(s): Genetic factors in colorectal cancer
2024 - Elsevier BV | Annals of Oncology
Marinde J. G. Bond, Karen Bolhuis, O. J. L. Loosveld, Jan Willem B. de Groot, Helga J. Droogendijk, Helgi H. Helgason, Mathijs P. Hendriks, Joost M. Klaase, Geert Kazemier, Mike S.L. Liem, Arjen M. Rijken, Cornelis Verhoef, Johannes H. W. de Wilt, Koert P. de Jong, Michael F. Gerhards, Martinus J. van Amerongen, Marc R. Engelbrecht, Krijn P. van Lienden, John J. Hermans, I. Quintus Molenaar, Dirk J. Grünhagen, Bart de Valk, Brigitte C.M. Haberkorn, Emile D. Kerver, Frans Erdkamp, Robbert J. van Alphen, Daniëlle Mathijssen‐van Stein, Aysun Komurcu, Anne M. May, Rutger‐Jan Swijnenburg, Cornelis J.A. Punt, Ronald M. van Dam, Gijs A. Patijn, Theo J. M. Ruers, T. Chapelle, Wouter K. G. Leclercq, Liselot Valkenburg‐van Iersel, Cecile Grootscholten, Joyce M. van Dodewaard-de Jong, Jeroen Vincent, Danny Houtsma, Maartje Los, Marien den Boer, Marija Trajkovic-Vidakovic, Theo van Voorthuizen, Miriam Koopman, J.H.M.J. Vestjens, Hans Torrenga, Leonie J. Mekenkamp, G.J. Veldhuis, Marco B. Polée, Serge E. Dohmen, Heidi Schut, Annelie J.E. Vulink, Henk K. van Halteren, Jamal Oulad Hadj, Pieter-Paul J.B.M. Schiphorst, Ronald Hoekstra,
In patients with colorectal cancer and unresectable liver-only metastases (CRLM), treatment with folinic acid, fluorouracil, and oxaliplatin (FOLFOX) plus irinotecan (FOLFOXIRI) and bevacizumab vs FOLFOX/folinic acid, fluorouracil, and irinotecan (FOLFIRI) plus bevacizumab increased progression-free survival, response, and R0/R1 resection/ablation rates, as well as toxic effects in RAS/BRAFV600E-variant and/or right-sided tumors. FOLFOX/FOLFIRI-panitumumab vs FOLFOX/FOLFIRI-bevacizumab increased response ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2024 - American Medical Association | JAMA Oncology
Iacopo Vagliano, Martijn J. Schut, Ameen Abu‐Hanna, Dave A. Dongelmans, Dylan W. de Lange, Diederik Gommers, Olaf L. Cremer, Rob J. Bosman, Sander Rigter, Evert‐Jan Wils, Tim Frenzel, Remko de Jong, Marco A. A. Peters, Marlijn J. A. Kamps, Dharmanand Ramnarain, Ralph Nowitzky, Fleur G. C. A. Nooteboom, Wouter de Ruijter, Louise C. Urlings‐Strop, Ellen G. M. Smit, D. Jannet Mehagnoul‐Schipper, Tom Dormans, Cornelis P. C. de Jager, Stefaan H. A. Hendriks, Sefanja Achterberg, Evelien Oostdijk, Auke C. Reidinga, Barbara Festen‐Spanjer, Gert B. Brunnekreef, Alexander D. Cornet, Walter van den Tempel, Age D. Boelens, Peter Koetsier, Judith Lens, Harald J. Faber, A. Karakus, Robert Entjes, Paul de Jong, Thijs C. D. Rettig, Merijn C. Reuland, M. Sesmu Arbous, Lucas M. Fleuren, Tariq A. Dam, Patrick Thoral, Robbert C. A. Lalisang, Michele Tonutti, Daan P. de Bruin, Paul Elbers, Nicolette F. de Keizer,
To assess, validate and compare the predictive performance of models for in-hospital mortality of COVID-19 patients admitted to the intensive care unit (ICU) over two different waves of infections. Our models were built with high-granular Electronic Health Records (EHR) data versus less-granular registry data. Observational study of all COVID-19 patients admitted to 19 Dutch ICUs participating in both the national quality registry National Intensive Care Evaluation (NICE) and the EHR-based Dutch Data ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - Elsevier BV | International Journal of Medical Informatics
Anne‐Rose W. Schut, Emma Lidington, Milea J. M. Timbergen, Eugenie Younger, Winette van der Graaf, Winan J. van Houdt, Johannes J. Bonenkamp, Robin L. Jones, Dirk J. Grünhagen, Stefan Sleijfer, Cornelis Verhoef, Spyridon Gennatas, Olga Husson,
Tópico(s): Soft tissue tumor case studies
2023 - Elsevier BV | European Journal of Surgical Oncology
Patricia Roth, Manuela Silginer, Simon L. Goodman, Kathy Hasenbach, Svenja Thies, Peter Schraml, Ghazaleh Tabatabai, Helga Moch, Isabel Tritschler, Michael Weller, Alessandro Perin, Federica Verginelli, Rola Dali, K. Hei Man Fung, R J Lo, Pierluigi Longatti, Marie Christine Guiot, Rolando F. Del Maestro, Stefania Rossi, Umberto di Porzio, O. Stechishin, Stefan Weiß, Stefano Stifani, M. Sanzey, A. Golebiewska, Daniel Stieber, Petr V. Nazarov, Antonio Muller, Lucia Vallar, Simone P. Niclou, Sean E. Lawler, E. Antonio Chiocca, Stainley Williams, Christina Wanka, J. P. Steinbach, Johannes Rieger, Iris Lavon, Daniel Zrihan, Miri Refael, T. Siegal, Peter Sminia, Krista A. van Nifterik, J. van den Berg, Vincent Lafleur, Lukas J.A. Stalpers, Ben J. Slotman, Anna Di Stefano, Victor Enciso-Mora, Y. Marie, V. Desestret, Marianne Labussière, Ahmed Idbaïh, Khê Hoang‐Xuan, J. Y. Delattre, Richard S. Houlston, Marc Sanson, Adelheid Wöehrer, Irene Slavc, Harald Stefanits, T. Waldhoer, H. Heinzl, N. Zielonke, Thomas Czech, Johannes A. Hainfellner, Christine Haberler, S. Zouaoui, A. Darlix, Jean‐Marc Virion, Valérie Rigau, Hélène Mathieu‐Daudé, F. Bauchet, Dominique Figarella‐Branger, Hugues Duffau, Luc Taillandier, Luc Bauchet, E. Naydenov, Roman S. Popov, R. Tanova, Krasimir Minkin, Steven De Vleeschouwer, Stefaan Van Gool, Guido Cavaletti, J. Wilbers, Frank Hoebers, Willem Boogerd, Erik van Werkhoven, Marlies E. Nowee, Gerald W. Hart, E. van Dijk, A. Kappelle, L. Dorresteijn, Mitsuhiro Furuse, T. Miyata, E. Yoritsune, Shun‐ichiro Kawabata, Takashi Kuroiwa, Shoichiro Miyatake, F. W. Boele, J.J. Heimans, N.K. Aaronson, Martin Taphoorn, Tjeerd J. Postma, Jaap C. Reijneveld, Marinella Klein, Esther J. J. Habets, Martin Taphoorn, S. Nederend, Marinella Klein, Dulce María Delgadillo, K. Hoang Xuan, A. C. Bottomley, Martin J. van den Bent, Jaap C. Reijneveld, Paola Flores, Olivier Chinot, Julie Berbis, P. Auquier, Priya Kumthekar, S. A. Grimm, Julia M. Chandler, Irene Helenowski, M. H. Marymont, Alfred Rademaker, Lena Wagner, B. V. Stell, Jeffery J. Raizer, Priya Kumthekar, Sara A. Grimm, Daniel Jacobs, B. V. Stell, Alfred Rademaker, Julia M. Chandler, M. H. Marymont, Irene Helenowski, Lena Wagner, Jeffery J. Raizer, G. Claudel, Cornelia Müller, K. Colmar, E. Garat, Pascal Beauchesne, Kasra Hassani, B. Bethune, P. Nguyen-Thi, Paolo Di Patrizio, Luc Taillandier, E. M. Sizoo, Martin Taphoorn, Bernard M.J. Uitdehaag, J.J. Heimans, L. Deliens, Jaap C. Reijneveld, H. W. Pasman, R Rampling, A. James, Patrick J. Mulholland, S. A. Peoples, O. Al-Salihi, Chris Twelves, Stephanie Halford, Lorraine J. B. McGuigan, Julie A. Ritchie, H. Sing-Jasuja, Ton N. Schumacher, Felix Sahm, Andreas von Deimling, Wolfgang Wick, Michael Platten, Hilko Ardon, Christian Ewelt, D. Gunes, Johannes Wölfer, Steven De Vleeschouwer, W. Stummer, Wolfgang Wick, Christoph Meisner, Bettina Hentschel, Michael Platten, Michael Sabel, Siegfried Koeppen, Ralf Ketter, M. Simon, Guido Reifenberger, Michael Weller, Jaime Gállego Pérez‐Larraya, Nicolás Samprón, Ander Matheu, Ángel Ayuso‐Sacido, Sébastien Paris, Sonia Tejada-Solís, Ricardo Díez-Valle, Adolfo López de Munaín, Lorea Manterola, Marta M. Alonso, Markus Weiler, Jonas Blaes, Felix Sahm, Stefan Pusch, Manfred Jugold, Tobias Kempf, Michael Weller, Michael Platten, Wolfgang Wick, K. L. McDonald, Robert W. Rapkins, L. Zhau, Megan P. Hitchins, Saurabh Kumar Agnihotri, Aaron S. Gajadhar, Thierry Gorlia, G.P. Margison, Kenneth Aldape, Christine Hawkins, Monika E. Hegi, Abhishek Guha, Marc Simó, M. Maciá, Gerard Plans, Carles Majós, Maria de las Mercedes Garcia Gil, Cristina Llorente, Roser Velasco, Jordi Bruna, T. Yanagisawa, Kazuo Suzuki, Kazuhito Fukuoka, T. Kohga, Jun-ichi Adachi, K. Mishima, Mitsuko Matsutani, Takahiro Fujimaki, R. Nisikawa, J. Kuhnhenn, Hendrik Pels, MF Reiser, Marcel Deckert, Gerlinde Egerer, Marlies Vogt‐Schaden, Gabriele Schackert, Frank Kroschinsky, Ingo G.H. Schmidt‐Wolf, Uwe Schlegel, Devora Schiff, Joe Taylor, Eoin P. Flanagan, Brian P. O’Neill, T. Siegal, Antonio Omuro, Joachim M. Baehring, A. Gonzalez-Aguilar, M. Chamberlain, Ryosuke Nishikawa, L. Zach, D.H. Guez, Y. Grober, David Last, D.W Daniels, Charles S. Hoffman, Oriel Nissim, Roberto Spiegelmann, Zoya Cohen, Yael Mardor, Andreas Radbruch, L. Kramp, Benedikt Wiestler, Susanne Heiland, Wolfgang Wick, Martin Bendszus, C. Colavolpe, Olivier Chinot, P. Métellus, Joseph A. Mancini, M. Barrié, C. Bequet-Boucard, Émeline Tabouret, O. Mundler, Dominique Figarella‐Branger, Emmanuel Guedj, Anna S. Berghoff, Hans Lassmann, Romana Höftberger, Matthias Preusser, S. Mercurio-Smit, Laëtitia Padovani, Christelle Colin, N. Andre, Cecília de Souza Fernandez, Dominique Figarella‐Branger, Roberta Rudà, Luca Bertero, Elena Trevisan, Amy J. Pace, C. M. Carapella, Cristina Dealis, Manuela Caroli, Marina Faedi,
SHP1 EXPRESSION IS EPIGENETICALLY REGULATED AND INFLUENCES THE SENSITIVITY TO CHEMOTHERAPEUTIC AGENTS IN GLIOBLASTOMA CELLS
Oxford University Press
Anne‐Rose W. Schut, Milea J. M. Timbergen, Danique van Broekhoven, Thijs van Dalen, Winan J. van Houdt, Frits van Coevorden, Johannes J. Bonenkamp, Sander D. Dijkstra, Marc H.A. Bemelmans, Lukas B. Been, Robert van Ginkel, Stefan Sleijfer, Dirk J. Grünhagen, Cornelis Verhoef,
Background: Desmoid-type fibromatosis (DTF) has a highly variable clinical course, displaying phases of progressive growth, stabilization or even spontaneous regression without treatment. Active surveillance (AS) is currently recommended as primary treatment. The aim of this study was to assess tumour behaviour and the efficacy of AS in DTF patients.
Tópico(s): Soft tissue tumors and treatment
2022 - Elsevier BV | European Journal of Surgical Oncology
Linda Nab, Chantal Visser, Bas C. T. van Bussel, Albertus Beishuizen, Remy H.H. Bemelmans, Hugo Ten Cate, F. Nanne Croles, Coen van Guldener, Cornelis P. C. de Jager, Menno V. Huisman, Marten R. Nijziel, Pieter W. Kamphuisen, Frederikus A. Klok, Stefanie Koster, Nuray Kuşadasi, Karina Meijer, Corstiaan A. den Uil, Roger E. G. Schutgens, Frank Stam, Alexander P. J. Vlaar, Eline A. Vlot, Marijke Linschoten, Folkert W. Asselbergs, Marieke J.H.A. Kruip, Saskia le Cessie, Suzanne C. Cannegieter, Jeroen van den Akker, Amein K. Al‐Ali, Fahd A Al-Muhanna, N. Y. Y. Al-Windy, Y. A. Almubarak, A. N. Alnafie, Mohammed Alshahrani, A. M. Alshehri, R. L. Anthonio, M. Louisa Antoni, Avinash Aujayeb, Diederik van de Beek, Jan Berg, Tom W. van de Berg, Ruben Bierings, Maartje van den Biggelaar, Wim Boersma, Bram van den Borst, Mettine H.A. Bos, Firdaouss Boutkourt, A. J. M. van Boxem, Rolf E. Brouwer, Matthijs C. Brouwer, Richard Bruggeman, J. Burggraaf, Sytze de Bruin, Gaby Captur, Massimo Caputo, Arina J. ten Cate‐Hoek, N. Charlotte, Michiel Coppens, Annie Cornet, Olaf L. Cremer, Paul Dark, Johan De Sutter, C. E. Delsing, H. G. R. Dorman, J. T. Drost, Renée A. Douma, Jeroen Eikenboom, Jacobien Ellerbroek, Mireille E. Emans, Henrik Endeman, Nick van Es, Paul L. den Exter, Harald J. Faber, Joyce Faber, Laura M. Faber, Janise Braga Barros Ferreira, Barbara Festen, Bas Franken, Laurence Gabriël, Wiek H. van Gilst, J.J. Miranda Geelhoed, Geert-Jan Geersing, Marco Goeijenbier, Diederik Gommers, Eric C. M. Van Gorp, B. E. Groenemeijer, Marco J.J.H. Grootenboers, Lianne R. de Haan, Thijs F. van Haaps, Tilman M. Hackeng, H. E. Haerkens-Arends, Gideon R. Hajer, Pim van der Harst, Behnam Hedayat, Dirk J. van der Heijden, Elias Hellou, Yvonne Henskens, Lisa Hessels, R. S. Hermanides, J.F. Hermans-van Ast, Cees M.P.M. Hertogh, M. W. J. van Hessen, Leo Heunks, Stéphane Heymans, I. C. C. van der Horst, Marcel M.C. Hovens, Jacqueline G. Hugtenburg, Anne‐Marije Hulshof, Nicole Hunfeld, Sabrina H. van Ierssel, L. S. D. Jewbali, Chang-Han Jong, Evert de Jonge, Nicole P. Juffermans, H. A. H. Kaasjager, Matthias Kant, Fleur H.J. Kaptein, Mark T. Kearney, Eva K. Kempers, H. A. M. van Kesteren, Marlies E. Kevenaar, Bas Kietselaer, Fleur S. Kleijwegt, Aafke M H Koning, Marion Koopmans, Janine van Kooten, P. Y. Kopylov, Johannes G. Krabbe, Kees Kramers, Lucia J.M. Kroft, A. F. M. Kuijper, Todd Kuiken, Johanna M. Kwakkel‐van Erp, Bas de Laat, Thomas Langerak, A. Lansbergen, Mandy N. Lauw, I. van der Lee, Frank W.G. Leebeek, J. Leentjes, Willem M. Lijfering, M. M. J. M. van der Linden, G. C. M. Linssen, Ton Lisman, Coen Maas, Moniek P.M. de Maat, Rosa Macías‐Ruiz, F. J. H. Magdelijns, F M A C Martens, Gerry P McCann, Pim van der Meer, J. C. M. Meijers, Daniek A. M. Meijs, M. F. L. Meijs, Peter Messiaen, Saskia Middeldorp, P. S. Monraats, Laura Montagna, Pim van Montfort, A. Moriarty, Arend Mosterd, Mark M. G. Mulder, Marcella C.A. Müller, P.R. Nierop, L. Nieuwenhuizen, Mathilde Nijkeuter, M.K. Ninaber, Danny Noack, Esther J. Nossent, Renske H. Olie, Clara E E van Ofwegen-Hanekamp, Evelien Oostdijk, Marthe S. Paats, Y M Pinto, Ron Pisters, Hamidreza Poorhosseini, Swati Prasad, Hein Putter, Mathijs Raadsen, S.R.S. Ramai, Josep Redón, A. C. Reidinga, M. I. A. Ribeiro, David P Ripley, Barry Rockx, Thirza J. Roest, Casper Rokx, Araci M. R. Rondon, Anna H.E. Roukens, Rehab Salah, E. Saneei, Manish Saxena, Jeroen Schaap, Dirk Schellings, Ilse M. Schrover, Carolina A. M. Schurink, Leon J. Schurgers, Astrid Schut, Akbar Shafiee, Angela C. Shore, Hans‐Marc J. Siebelink, Koen S. Simons, Maarten van Smeden, Mark J R Smeets, Peter Smits, Yvo M. Smulders, Y.L. Soei, Brigitte M. Sondermeijer, Bart Spaetgens, Henri M.H. Spronk, Susanne Stads, Milou A.M. Stals, A. Stemerdink, Elena Tessitore, Y.I.G. van Tichelaar, Robert G Tieleman, Janneke Tijmensen, Philippe Timmermans, R. A. Tio, Fleur V.Y. Tjong, Kirby Tong‐Minh, Leon M. van den Toorn, Pieter R. Tuinman, Daan J.L. van Twist, Rolf T. Urbanus, Emeline M. Van Craenenbroeck, H. P. A. A. van Veen, Thiemo Veneman, Derk O. Verschure, Henri H. Versteeg, Roel Vink, Hubert W. Vliegen, Bart J.M. van Vlijmen, Anton Vonk Noordegraaf, Jan Voorberg, Jeroen K. de Vries, Esther G.M. De Waal, R. M. A. van de Wal, D. J. van de Watering, I. C. D. Westendorp, P. H. M. Westendorp, Brigitte Westerhof, Jan Westerink, Caroline Weytjens, Eric Wierda, B. Williams, Evert‐Jan Wils, Kristien Winckers, Marije ten Wolde, Pier Woudstra, K. W. Wu, Ruben Zaal, A G Zaman, P. M. van der Zee,
Tópico(s): COVID-19 and healthcare impacts
2025 - Nature Portfolio | Scientific Reports
Douwe J. Spaanderman, Stefanie Hakkesteegt, David Hanff, A R W Schut, Loes M. Schiphouwer, Melissa Vos, Christina Messiou, Simon Doran, Robin L. Jones, Andrew Hayes, Lorenzo Nardo, Yasser G. Abdelhafez, Atef Moawad, Khaled M. Elsayes, S. Lee, T.M. Link, Wiro J. Niessen, Geert J.L.H. van Leenders, Jacob J. Visser, Stefan Klein, Dirk J. Grünhagen, Cornelis Verhoef, Martijn P. A. Starmans,
As differentiating between lipomas and atypical lipomatous tumors (ALTs) based on imaging is challenging and requires biopsies, radiomics has been proposed to aid the diagnosis. This study aimed to externally and prospectively validate a radiomics model differentiating between lipomas and ALTs on MRI in three large, multi-center cohorts, and extend it with automatic and minimally interactive segmentation methods to increase clinical feasibility.
Tópico(s): Soft tissue tumor case studies
2024 - Elsevier BV | EClinicalMedicine