National Bureau of Economic Research (NBER)
J. Gerdes, Isabella Klein, B. L. DeVald, J. S. Burks,
... cross-reactivity to each other and to murine coronavirus A59, weak cross-reactivity to murine coronavirus JHM, but no cross-reactivity to the human coronavirus 229E. Antiserum to SK or SD failed to inhibit hemagglutination of chicken erythrocytes by the human coronavirus OC43. However, OC43 antiserum neutralized both SD and SK. Specific coronavirus polypeptides were identified and compared by immunoprecipitation and ...
Tópico(s): Viral Infections and Immunology Research
1981 - American Society for Microbiology | Journal of Virology
Niels C. Pedersen, John Boyle, K Floyd, Alan M. Fudge, J. S. F. Barker,
An enteric coronavirus that is antigenically closely related to feline infectious peritonitis virus (FIPV) is ubiquitous in the cat population. This virus has been designated feline enteric coronavirus to differentiate it from FIPV. The virus is ... in young specific-pathogen-free kittens. Feline enteric coronavirus selectively infects the apical columnar epithelium of the ... or granulomatous disease. The relationship of feline enteric coronavirus and FIPV was studied. Although the viruses were ... were distinctly different in their pathogenicities. The enteric coronavirus did not cause feline infectious peritonitis in coronavirus ...
Tópico(s): Virus-based gene therapy research
1981 - American Veterinary Medical Association | American Journal of Veterinary Research
National Bureau of Economic Research (NBER)
Kunihiko Sato, Yuji Inaba, Yasuo Miura, S. Tokuhisa, Hiroomi Akashi, T Shinozaki, M. Matumoto,
... 625 NoteFree Access Neutralizing Antibody to Calf Diarrhea Coronavirus in Various Animal Species in Japan Kunihiko Sato, ... 1Bass, E. P., and Sharpee, R. L. 1975. Coronavirus and gastroenteritis in foals. Lancet 2: 822. 10. ... A. J. 1974. Recovery and characterization of a coronavirus from military dogs with diarrhea. Proc. U.S. ... Y., and Matumoto, M. 1976. Replication of bovine coronavirus in cell line BEK-1 culture. Arch. Virol. ... calf diarrhea: propagation, attenuation and characteristics of a coronavirus-like agent. Am. J. Vet. Res. 34: 145– ...
Tópico(s): Virus-based gene therapy research
1981 - Wiley | Microbiology and Immunology
National Bureau of Economic Research (NBER)
Brenda G. Hogue, Bernadette King, David A. Brian,
... pair of major structural proteins of the bovine coronavirus (Mebus strain) were used in immunoblotting studies to ... reactivity with the structural proteins of the human coronavirus OC43 and the mouse hepatitis coronavirus A59. We conclude that the bovine coronavirus is comprised of four major structural proteins, gp190 ( ... kilodalton subunits), gp140, pp52, and gp26. The human coronavirus OC43 has an antigenically homologous counterpart of similar ...
Tópico(s): Viral gastroenteritis research and epidemiology
1984 - American Society for Microbiology | Journal of Virology
National Bureau of Economic Research (NBER)
Peter W. de Leeuw, J. W. A. Tiessink,
... vax®‐2, Smith Kline) against rotavirus and/or coronavirus induced diarrhoea was examined under controlled conditions. Calves ... a mixture of virulent bovine rotavirus and bovine coronavirus. In the first experiments calves received colostrum free ... 12.5 per cent body weight. Rotavirus and coronavirus shedding was found in all three. In contrast, ... vaccination one shed rotavirus and one rotavirus plus coronavirus, but no virus excretion was found after the ... the beginning of diarrhoea coincided with rotavirus and coronavirus excretion. These calves lost six to seven per ...
Tópico(s): Plant Virus Research Studies
1985 - Wiley | Zentralblatt für Veterinärmedizin Reihe B
F. Bürki, Karin Möstl, E. Spiegl, Eleonora Horvath, Hajnal Székely,
... University's Field Station. In previous investigations bovine coronavirus had been determined as the most pathogenic enteric ... trivalent commercial vaccine containing live attenuated rotavirus and coronavirus plus K 99 + antigen of E. coli (Scourguard ... day 14 after birth for both rotavirus and coronavirus antigens. Shedding of enteropathogenic E. coli and of ... also controlled. Furthermore, antibody titres against rotavirus and coronavirus were determined in cows' blood serum, colostrum and ... unvaccinated dams were perorally challenged with rotavirus and coronavirus, again daily screening their fecal samples for virus‐ ...
Tópico(s): Animal Virus Infections Studies
1986 - Wiley | Journal of Veterinary Medicine Series B
James F. Evermann, Jonathan L. Heeney, A. J. McKeirnan, Stephen J. O’Brien,
A coronavirus which was isolated from a cheetah (Acinonyx jubatus) that succumbed to feline infectious peritonitis was characterized in ... a persistent infection (CrFK 83-4497). The cheetah coronavirus was compared with other members of the feline coronavirus group including the feline enteric coronavirus (FECV) 79-1683 and the feline infectious peritonitis ... FIPV), 79-1146, and UCD-1. The cheetah coronavirus was demonstrated to have a restricted host-cell ... perinuclear region of cells infected with the cheetah coronavirus. Ultrastructural studies of the cheetah coronavirus indicated a ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
1989 - Elsevier BV | Virus Research
Kam‐Leung Siu, Kin‐Hang Kok, Ming-Him James Ng, Vincent Kwok‐Man Poon, Kwok‐Yung Yuen, Bo-Jian Zheng, Dong‐Yan Jin,
Severe acute respiratory syndrome (SARS) coronavirus is highly pathogenic in humans and evades innate immunity at multiple levels. It has evolved various strategies to counteract the production ... infection. In this study we demonstrate that SARS coronavirus M protein inhibits gene transcription of type I ... findings reveal a new mechanism by which SARS coronavirus circumvents the production of type I interferons. Severe acute respiratory syndrome (SARS) coronavirus is highly pathogenic in humans and evades innate ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2009 - Elsevier BV | Journal of Biological Chemistry
Qin Chen, Jian Li, Zhirui Deng, Wei Xiong, Quan Wang, Yong-Qiang Hu,
Based on microarray hybridization, a diagnostic test for coronavirus infection was developed using eight coronavirus strains: canine coronavirus (CCoV), feline infectious peritonitis virus (FIPV), feline coronavirus (FCoV), bovine coronavirus (BCoV), porcine respiratory coronavirus (PRCoV), turkey enteritis coronavirus (TCoV), transmissible gastroenteritis virus (TGEV), and human respiratory coronavirus (HRCoV). Up to 104 cDNA clones of eight ...
Tópico(s): Viral gastroenteritis research and epidemiology
2009 - Karger Publishers | Intervirology
Patrick C. Y. Woo, Susanna K. P. Lau, Yi Huang, Kwok‐Yung Yuen,
... SARS epidemic has boosted interest in research on coronavirus biodiversity and genomics. Before 2003, there were only ... genomes sequenced. These include two human coronaviruses (human coronavirus NL63 and human coronavirus HKU1), 10 other mammalian coronaviruses [bat SARS coronavirus, bat coronavirus (bat-CoV) HKU2, bat-CoV HKU4, bat-CoV ... bat-CoV 512/2005, bat-CoV 1A, equine coronavirus, and beluga whale coronavirus] and four avian coronaviruses (turkey coronavirus, bulbul coronavirus HKU11, thrush coronavirus HKU12, and munia ...
Tópico(s): Viral gastroenteritis research and epidemiology
2009 - SAGE Publishing | Experimental Biology and Medicine
Daniel N. Lewicki, Thomas Gallagher,
Oligomeric spike (S) glycoproteins extend from coronavirus membranes. These integral membrane proteins assemble within the endoplasmic reticulum of infected cells and are subsequently endoproteolyzed in the Golgi, generating noncovalently ... triggered entry. Oligomeric spike (S) glycoproteins extend from coronavirus membranes. These integral membrane proteins assemble within the ... Scholar). Our studies have focused on murine hepatitis coronavirus (MHV) 1The abbreviations used are: MHVmurine hepatitis virusCEACAMcarcinoembryonic ...
Tópico(s): Virus-based gene therapy research
2002 - Elsevier BV | Journal of Biological Chemistry
Dimitrios P. Kontoyiannis, Renata Pasqualini, Wadih Arap,
... that causes disease elusive. However, a previously unknown coronavirus, with or without another viral copathogen, has been ... Erdman D Goldsmith C et al.A novel coronavirus associated with severe acute respiratory syndrome.N Engl ... Scholar The involvement of a member of the coronavirus family, a large group of sizeable single-stranded ... to the two principal and antigenically-distinct human coronavirus strains, 229E and OC43,2McIntosh K Coronaviruses.in: ... edn. Churchill Livingston, Philadelphia2000Google Scholar the SARS-causing coronavirus is a novel strain.1Ksiazek TG Erdman D ...
Tópico(s): vaccines and immunoinformatics approaches
2003 - Elsevier BV | The Lancet
Julian A. Tanner, Rory M. Watt, Yubo Chai, Lin‐Yu Lu, Marie C.M. Lin, Malik Peiris, Leo L. M. Poon, Hsiang‐Fu Kung, Jian‐Dong Huang,
... NTPase/helicase protein from severe acute respiratory syndrome coronavirus (SARS-CoV) is postulated to play a number ... NTPase/helicase protein from severe acute respiratory syndrome coronavirus (SARS-CoV) is postulated to play a number ... used are: SARS, severe acute respiratory syndrome; CoV, coronavirus; MBD, metal binding domain; EAV, equine arteritis virus; ... in humans was recently identified as a novel coronavirus, SARS coronavirus (SARS-CoV), an enveloped, single-stranded RNA positive- ... Cloning—Cultured Vero cells were infected with SARS coronavirus strain HKU 39487. Total RNA was isolated with ...
Tópico(s): Viral Infections and Immunology Research
2003 - Elsevier BV | Journal of Biological Chemistry
John Oxford, S. Bossuyt, Rob Lambkin‐Williams,
... case the cause of SARS the newly identified coronavirus.1 It has been recognised for four decades ... SARS virus. Woodwork by Tom Brooke. Overall the coronavirus family was viewed as causing mild upper respiratory tract infections, cough and sore throat. The human coronavirus to date has not proven to be easily ... own. The other three groupings are the human coronavirus 229E and porcine epidemic diarrhoea (group I); bovine coronavirus, mouse hepaptitis virus and human coronavirus OC43 (group II); and avian infectious bronchitis (group ...
Tópico(s): COVID-19 Clinical Research Studies
2003 - Wiley | Immunology
Oleg V. Krokhin, Yan Li, Anton Andonov, Heinz Feldmann, Ramon Flick, Steven J.M. Jones, Ute Ströeher, Nathalie Bastien, Kumar Dasuri, Keding Cheng, J. Neil Simonsen, Hélène Perreault, John A. Wilkins, Werner Ens, Frank Plummer, Kenneth G. Standing,
A new coronavirus has been implicated as the causative agent of severe acute respiratory syndrome (SARS). We have used convalescent sera ... for prophylactic intervention in combating SARS. A new coronavirus has been implicated as the causative agent of ... laboratories around the world that suggested a distinct coronavirus may be etiologically involved. In particular, the laboratory ... effort to determine the genome sequence for the coronavirus (4Marra M.A. Jones S.J. Astell C. ... L. The genome sequence of the SARS-associated coronavirus.Science. May 1, 2003; 300: 1399-1404Google Scholar), ...
Tópico(s): SARS-CoV-2 detection and testing
2003 - Elsevier BV | Molecular & Cellular Proteomics
Jiun‐Ling Wang, Jann‐Tay Wang, Chong‐Jen Yu, Yee‐Chun Chen, Po‐Ren Hsueh, Chêng Hsiao, Chuan‐Liang Kao, Shan‐Chwen Chang, Pan‐Chyr Yang,
... and viral load in a community outbreak of coronavirus-associated SARS pneumonia a prospective study.Lancet. 2003; ... Vero cells from a throat swab yielded a coronavirus. SARS-associated coronavirus infection was confirmed by detection of coronavirus ribonucleic acid by real-time reverse transcription polymerase ... swab, sputum, and stool that were positive for coronavirus. Indirect fluorescent antibody to SARS-associated coronavirus was also positive. Serum creatine kinase level increased ... negative, except for detection of antibody to SARS coronavirus by indirect fluorescent antibody assay. SARS-associated coronavirus ...
Tópico(s): Cardiovascular Effects of Exercise
2003 - Elsevier BV | The American Journal of Medicine
Earl G. Brown, Jason A. Tetro,
... 3Peiris JSM Lai ST Poon LLM et al.Coronavirus as a possible cause of severe acute respiratory ... Erdman D Goldsmith CS et al.A novel coronavirus associated with severe acute respiratory syndrome.N Engl ... This newly identified virus has been designated SARS coronavirus (SARS-CoV).5World Health Organization Update 31: coronavirus never before seen in humans is the cause ... Preiser W et al.Identification of a novel coronavirus in patients with severe acute respiratory syndrome.N ... Oberste MS Monroe SS Characterization of a novel coronavirus associated with severe acute respiratory syndrome.Science. 2003; ( ...
Tópico(s): Viral gastroenteritis research and epidemiology
2003 - Elsevier BV | The Lancet
Volker Thiel, Nadja Karl, Barbara Schelle, Petra Disterer, Ingo M. Klagge, Stuart G. Siddell,
ABSTRACT Coronavirus genomes are the largest known autonomously replicating RNAs with a size of ca. 30 kb. They are ... developed a multigene expression vector based on human coronavirus 229E. We have constructed a prototype RNA vector ... the 5′ and 3′ ends of the human coronavirus genome, the entire human coronavirus replicase gene, and three reporter genes (i.e., ... reporter gene is located downstream of a human coronavirus transcription-associated sequence, which is required for the ... mRNAs. The transfection of vector RNA and human coronavirus nucleocapsid protein mRNA into BHK-21 cells resulted ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2003 - American Society for Microbiology | Journal of Virology
David S.C. Hui, Joseph J.�Y. Sung,
... 1994Crossref PubMed Scopus (1975) Google Scholar A novel coronavirus (CoV) is now identified as the main pathogen ... 8Peiris JS Lai ST Poon LL et al.Coronavirus as a possible cause of severe acute respiratory ... Preiser W et al.Identification of a novel coronavirus in patients with severe acute respiratory syndrome.N ... Erdman D Goldsmith CS et al.A novel coronavirus associated with severe acute respiratory syndrome.N Engl ... Monroe SS et al.Characterization of a novel coronavirus associated with severe acute respiratory syndrome.Available at: ...
Tópico(s): Viral gastroenteritis research and epidemiology
2003 - Elsevier BV | CHEST Journal
... R. et al. (1983). Coronaviridae—report of the coronavirus study group. Intervirology, 20, 181–189. 10.1159/ ... J. and Vaughn, A. L. (1973). Dectection of coronavirus strain 692 by immune electron microscopy. Infect. Immun., ... L. and Zikmundova, L. (1980). Isolation of Tettnang coronavirus from man. Acta Virol., 24, 363–366. CASPubMedWeb ... Morey, F. (1987). Characteristics of Australian human enteric coronavirus-like particles: comparison with human respiratory coronavirus 229E and duodenal brush border vesicles. Arch. Virol., ...
Tópico(s): Animal Virus Infections Studies
1994 - Wiley | Reviews in Medical Virology
Ari Bitnun, Stanley Read, Raymond Tellier, Martin Petric, Susan E. Richardson,
... experience of suspected severe acute respiratory syndrome-associated coronavirus infections in children was published without microbiological findings. ... update on pediatric severe acute respiratory syndrome-associated coronavirus infections in Toronto, Ontario, Canada, that includes microbiological ... 2003, with suspect severe acute respiratory syndrome-associated coronavirus infection were included. A proven case was defined ... criteria for suspect severe acute respiratory syndrome-associated coronavirus infection and demonstrated a serologic response to severe ...
Tópico(s): Viral gastroenteritis research and epidemiology
2008 - American Academy of Pediatrics | PEDIATRICS
Emily G. Severance, Ioannis Bossis, Faith Dickerson, Cassie Stallings, Andrea Origoni, Anne Sullens, Robert H. Yolken, Raphael P. Viscidi,
... NL63. To measure exposure rates to these four coronavirus strains (229E, HKU1, NL63, and OC43), we devised ... based on amino- and carboxy-terminally tagged recombinant coronavirus nucleocapsid antigens. Four human and one feline coronavirus antigen were cloned into baculoviruses expressed in insect ... children. The proportion of seropositive adults for each coronavirus was as follows: 229E, 91.3%; HKU1, 59. ... of a significant serological response to the feline coronavirus was observed. Significant associations of coronavirus seropositivity and ...
Tópico(s): Virus-based gene therapy research
2008 - American Society for Microbiology | Clinical and Vaccine Immunology
... However, that changed in 2003, when a new coronavirus emerged, designated as severe acute respiratory syndrome corona- ... develop treatments for this new virus. Knowledge of coronavirus virology multiplied exponentially and, more importantly, quickly. Within ... tries to summarize the most recent advances in coronavirus molecular biology, vaccine development and coronavirus therapeutics, with great emphasis on SARS-CoV. The ... the most respected experts in the field of coronavirus research. The book consists of 16 chapters divided ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2008 - Future Medicine | Future Virology