Ryan Martin, Michael Balch, Scott Ferson,
... in confidence distributions! 1. IntroductionThanks to Drs Céline Cunen, Nils Lid Hjort and Tore Schweder for their ... in our paper.However, the message presented by Cunen et al. [3]—that replacing a Bayesian posterior ... 2. CDs only offer some CIn the abstract, Cunen et al. [3] present their take-home message: ... Cy(d) denote the distribution function that determines Cunen et al.'s CD, i.e. Cy(d)= ... risk of being systematically wrong. Therefore, contrary to Cunen et al.'s claim, their CD is not ... statistician astray ([5], p. 59). This is why Cunen et al. [3] do not start with a ...
Tópico(s): Advanced Statistical Methods and Models
2021 - Royal Society | Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences
Piotr Sorokowski, Andrzej Szmajke, Agnieszka Sorokowska, Maryann Borg Cunen, Marharyta Fabrykant, Kiumars Zarafshani, Manochehr Amiri, Saeideh Bazzāziān, Biljana Blaževska–Stoilkovska, Veronica Casellas, Hakan Çetinkaya, Berenice López Coutiño, Maria Lourdes L. Chavez, Cecilia Cheng, Ioana A. Cristea, Daniel David, Seda Dural, Anna M. Dzieciol, Sofian Fauzee, Ana Frichand, Evrim Gülbetekin, Ivana Hromatko, Tina Javahishvili, Anna Jgenti, Sandi Kartasasmita, Khadijeh Moradi, Bojan Musil, Sonia Nongmaithem, E. Oluka Yode Oladipo, Oluyinka Ojedokun, Kanak Patil, Wanda Schell, Hasmig Serpekian, Borislav Slavchev, Stanislava Stoyanova, Meri Tadinac, Nachiketa Tripathi, Tzu Fang,
The leg-to-body ratio (LBR) is a morphological index that has been shown to influence a person’s attractiveness. In our research, 3,103 participants from 27 nations rated the physical attractiveness of seven male and seven female silhouettes varying in LBR. We found that male and female silhouettes with short and excessively long legs were perceived as less attractive across all nations. Hence, the LBR may significantly influence perceptions of physical attractiveness across nations.
Tópico(s): Eating Disorders and Behaviors
2010 - SAGE Publishing | Journal of Cross-Cultural Psychology

Antonio Terracciano, Ahmed M. Abdel–Khalek, Naeem I Adam, Lucia Adamovová, Changsun Ahn, Hyun Nie Ahn, Bader M. Alansari, Lidia Alcalay, Jüri Allïk, Alois Angleitner, María Dolores Avia, Lindsay E. Ayearst, Claudio Barbaranelli, Andrew Beer, M. A. Borg-Cunen, Denis Bratko, Marina Brunner-Sciarra, L. Budzinski, Nathalie Camart, Donatien Dahourou, F. De Fruyt, Margarida Pedroso de Lima, G. E. H. del Pilar, E Diener, Ruth Falzon, Kumari Fernando, Emília Ficková, Ronald Fischer, Carmen Flores-Mendoza, M. Arif Ghayur, Sami̇ Gülgöz, Bo Hagberg, Jamin Halberstadt, Magdalena S. Halim, Martina Hřebı́čková, John Humrichouse, Hans Henrik Jensen, Dragana Djurić Jočić, Fridrik H. Jonsson, Brigitte Khoury, Waldemar Klinkosz, Goran Knežević, Mary Anne Lauri, Nora Leibovich, Thomas Martin, Ivan Marušič, Khairul Anwar Mastor, David Matsumoto, Margaret McRorie, B. Meshcheriakov, Erik Lykke Mortensen, M. Munyae, János Nagy, Kazuhiro Nakazato, Florence Nansubuga, Shigehiro Oishi, Oluyinka Ojedokun, Fritz Ostendorf, Delroy L. Paulhus, Сергей Игоревич Пелевин, Jean‐Michel Petot, N. Podobnik, José Luis Porrata, V. S. Pramila, Garry Prentice, Anu Realo, Norma Reátegui Colareta, Jean-Pierre Rolland, Jérôme Rossier, Willibald Ruch, Velko Rus, María Luisa Sánchez-Bernardos, Vanina Schmidt, S. Sciculna-Calleja, Andrzej Sękowski, Jane Shakespeare‐Finch, Yoshiko Shimonaka, Franco Simonetti, Tilahun Sineshaw, Jerzy Siuta, Peter B. Smith, Paul D. Trapnell, Krista K. Trobst, Lei Wang, Michelle Yik, Anthony J. Zupancic, Robert R. McCrae,
Most people hold beliefs about personality characteristics typical of members of their own and others' cultures. These perceptions of national character may be generalizations from personal experience, stereotypes with a "kernel of truth," or inaccurate stereotypes. We obtained national character ratings of 3989 people from 49 cultures and compared them with the average personality scores of culture members assessed by observer ratings and self-reports. National character ratings were reliable but ...
Tópico(s): Social and Intergroup Psychology
2005 - American Association for the Advancement of Science | Science

David P. Schmitt, Lidia Alcalay, Melissa Allensworth, Jüri Allïk, Lara K. Ault, Ivars Austers, Kevin Bennett, Gabriel Bianchi, Fredrick A. Boholst, Mary Ann Borg Cunen, Johan Braeckman, Edwin G. Brainerd, Leo Gerard A. Caral, Gabrielle Caron, María Martina Casullo, Michael R. Cunningham, Ikuo Daibo, Charlotte De Backer, Eros De Souza, Rolando Díaz‐Loving, Gláucia Ribeiro Starling Diniz, Kevin Durkin, Marcela Echegaray, Ekin Eremsoy, Harald Α. Euler, Ruth Falzon, Maryanne L. Fisher, Dolores Foley, Robert L. Fowler, Douglas P. Fry, Sirpa Fry, M. Arif Ghayur, Vijai N. Giri, Debra L. Golden, Karl Grammer, Liria Grimaldi, Jamin Halberstadt, Shamsul Haque, Dora Herrera, Janine Hertel, Amanda Hitchell, Heather Hoffmann, Danica T. Hooper, Zuzana Hradilekova, Jasna Hudek‐Knežević, Allen I. Huffcutt, Jas Laile Jaafar, Margarita Jankauskaitė, Heidi Kabangu-Stahel, Igor Kardum, Brigitte Khoury, Hayrran Kwon, Kaia Laidra, Anton‐Rupert Laireiter, Dustin Lakerveld, Ada Lampert, Mary Anne Lauri, Marguerite Lavallée, Suk-Jae Lee, Chung‐Leung Luk, Kenneth D. Locke, Vance Locke, Ivan Lukšík, Ishmael Magaisa, Dalia Marcinkevičienė, André Mata, Rui Mata, Barry McCarthy, Michael E. Mills, Nhlanhla Mkhize, João Manuel Moreira, Sérgio Moreira, Miguel Moya, M. Munyae, Patricia Noller, Hmoud Al-Olimat, Adrian Opre, Alexia Panayiotou, Nebojša Petrović, Karolien Poels, Miroslav Popper, Maria Poulimenou, Volodymyr P'Yatokha, Michel Raymond, Ulf‐Dietrich Reips, Susan E. Reneau, Sofía Rivera Aragón, Wade C. Rowatt, Willibald Ruch, Velko Rus, Marilyn P. Safir, Sonia Salas, Fabio Sambataro, Kenneth Sandnabba, Rachel Schleeter, Marion K. Schulmeyer, Astrid Schütz, Tullio Scrimali, Todd K. Shackelford, Mithila B. Sharan, Phillip R. Shaver, Francis Sichona, Franco Simonetti, Tilahun Sineshaw, R. Sookdew, Tom Speelman, Spyros Spyrou, H. Canan Sümer, Nebi Sümer, Marianna Supeková, Tomasz Szlendak, Robin Taylor, Bert Timmermans, William Tooke, Ioannis Tsaousis, Felician S.K. Tungaraza, Ashley Turner, Griet Vandermassen, Tim Vanhoomissen, Frank Van Overwalle, Ine Vanwesenbeeck, Paul L. Vasey, João Veríssimo, Martin Voracek, Wendy W. N. Wan, Ta-Wei Wang, Petr Weiss, Andik Wijaya, Liesbeth Woertman, Gahyun Youn, Agata ZupanÈiÈ,
As part of the International Sexuality Description Project, a total of 17,804 participants from 62 cultural regions completedthe RelationshipQuestionnaire(RQ), a self-reportmeasure of adult romanticattachment. Correlational analyses within each culture suggested that the Model of Self and the Model of Other scales of the RQ were psychometrically valid within most cultures. Contrary to expectations, the Model of Self and Model of Other dimensions of the RQ did not underlie the four-category model ...
Tópico(s): Marriage and Sexual Relationships
2004 - SAGE Publishing | Journal of Cross-Cultural Psychology
Nicole Borg Cunen, Jenny McNeill, Karen Murray,
to systematically identify interventions that midwives could introduce to address post-traumatic stress in women following childbirth. a search strategy was developed and relevant papers were identified from databases including Cinahl, Cochrane Library, EMBASE, Maternity and Infant Care, MEDLINE, PsycINFO, and Web of Science. Key search terms used were post-traumatic stress, post partum, intervention, controlled trial and review. Papers eligible for inclusion were primary studies and reviews of ...
Tópico(s): Pregnancy-related medical research
2013 - Elsevier BV | Midwifery
Libby Porter, Marc Martí-Costa, Marc Dalmau Torvà, Efrat Cohen-Bar, Ayala Ronel, Dallas Rogers, Andrew Cumbers, Neil Gray, Natascha Klocker, Chris Gibson, Harmen de Hoop,
... NIMK-Amsterdam, Museum Het Valkhof-Nijmegen, Museum Jan Cunen-Oss. Email: contact@harmendehoop.com
Tópico(s): Housing, Finance, and Neoliberalism
2013 - Routledge | Planning Theory & Practice
Nicole Borg Cunen, Julie Jomeen, Rita Borg Xuereb, Angela Poat,
Expectant parents develop varying degrees of emotional affiliation with the unborn child. Interventions supporting this relationship may be beneficial given its link to maternal health behaviour during pregnancy, as well as the parental-infant bond after birth.To identify and describe the effects of programmes and strategies that have addressed the parental-fetal relationship.English-language primary studies, published between 2005-2015, were identified and their methodological quality was assessed. ...
Tópico(s): Infant Development and Preterm Care
2016 - Elsevier BV | Women and Birth
Cunen Wu, Yuwen Zhuang, Shan Jiang, Shenlin Liu, Jin‐Yong Zhou, Jian Wu, Yuhao Teng, Baomei Xia, Ruiping Wang, Xi Zou,
Gastric cancer (GC) is the third primary cause of cancer-related mortality and one of the most common type of malignant diseases worldwide. Despite remarkable progress in multimodality therapy, advanced GC with high aggressiveness always ends in treatment failure. Epithelial-mesenchymal transition (EMT) has been widely recognized to be a key process associating with GC evolution, during which cancer cells go through phenotypic variations and acquire the capability of migration and invasion. Wnt/β- ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2016 - Spandidos Publishing | International Journal of Oncology
Yuwen Zhuang, Cunen Wu, Jin‐Yong Zhou, Xu Chen, Jian Wu, Shan Jiang, Haiyan Peng, Xi Zou, Jia‐yun Liu, Dapeng Wu, Tao Gong, MING-HAO QI, Tian Xue, Shenlin Liu, Hui Cai,
Solasodine is a main active component isolated from Solanum incanum L. that performs a wide range of functions containing anti‐oxidant, anti‐infection, and neurogenesis promotion. In this study, we explored the influence of solasodine on three types of human colorectal cancer ( CRC ) cell lines. The results show that solasodine prohibited CRC cell proliferation dose‐ and time‐dependently and impeded CRC cell motility by downregulating MMP s. Solasodine was also found to fuel caspase‐cascade reaction ...
Tópico(s): Potato Plant Research
2017 - Wiley | Cancer Science
Céline Cunen, Gudmund Horn Hermansen, Nils Lid Hjort,
Suppose observations y1,…,yn stem from a parametric model f(y,θ), with the parameter taking one value θL for y1,…,yτ and another value θR for yτ+1,…,yn. This article provides and examines two different general strategies for not merely estimating the break point τ but also to complement such an estimate with full confidence distributions, both for the change-point τ and for associated measures of differences between the two levels of θ. The first idea worked with involves testing homogeneity for ...
Tópico(s): Financial Risk and Volatility Modeling
2017 - Elsevier BV | Journal of Statistical Planning and Inference
Cunen Wu, Yuwen Zhuang, Shan Jiang, Fang Tian, Yuhao Teng, Xu Chen, Pei-Qiu Zheng, Shenlin Liu, Jin‐Yong Zhou, Jian Wu, Ruiping Wang, Xi Zou,
Cinnamaldehyde, the main chemical component of the essential oil separated from the traditional herb Cinnamomum cassia, has been demonstrated to be an efficient cytotoxic agent against several human cancers. The present experiment showed that cinnamaldehyde dose-dependently depresses the proliferation of three types of NSCLC cells and induces cell apoptosis in vitro and in vivo. Moreover, cinnamaldehyde attenuated CoCl2-induced EMT and decreased matrix metalloprotease (MMP) family while the in vivo ...
Tópico(s): Cancer-related Molecular Pathways
2017 - Elsevier BV | The International Journal of Biochemistry & Cell Biology
Yuwen Zhuang, Cunen Wu, Jin‐Yong Zhou, Zhiming Zhao, Chunli Liu, Junyi Shen, Hui Cai, Shen-Lin Liu,
Adverse side effects of conventional chemotherapy, acquired resistance and fatal tumor metastasis of human colorectal cancer (CRC) are propelling the exploration for novel selective anticarcinogens. Solasodine is a main active component isolated from Solanum incanum L that exhibited a potent stemness and invasion inhibitory effect on human colorectal cancer HCT116 cells. Colony Spheroid formation assay showed that solasodine dose-dependently prohibited HCT116 cell stemness. CD133, CD44, Nanog, Oct- ...
Tópico(s): Phytochemical Studies and Bioactivities
2018 - Elsevier BV | Biochemical and Biophysical Research Communications
Jin‐Yong Zhou, Min Chen, Cunen Wu, Yuwen Zhuang, Yugen Chen, Shenlin Liu,
The modified Si-Jun-Zi Decoction (SJZ), a Chinese medicine formula, is clinically used against multiple malignancies including colorectal cancer (CRC). This study aims to evaluate the effect of modified SJZ on CRC liver metastasis and identify the therapeutic mechanisms.Human CRC cells with GFP fluorescence were transplanted into Balb/c nude mice spleens. Modified SJZ, 5-fluorouracil or the combined treatment was given for 3 weeks. CRC liver metastasis was measured by fluorescence imaging and plasma ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2019 - BioMed Central | BMC Complementary and Alternative Medicine
Cunen Wu, Yuwen Zhuang, Jin‐Yong Zhou, Shenlin Liu, Ruiping Wang, Peng Shu,
Oxaliplatin has been widely applied in clinical tumor chemotherapy, the treatment failure of which mainly blames on low susceptibility resulted from intrinsic or acquired drug resistance in tumor cells. Microenvironmental hypoxia is one of the important pathological features of solid tumors, which is closely related to the radiochemotherapy tolerance and poor prognosis. Cinnamaldehyde is extracted from Cinnamomum cassia with inhibiting effect against kinds of tumors. In this study, we demonstrated ...
Tópico(s): Cancer-related Molecular Pathways
2019 - Elsevier BV | Experimental Cell Research
Céline Cunen, Nils Lid Hjort, Håvard Mokleiv Nygård,
Have great wars become less violent over time, and is there something we might identify as the long peace? We investigate statistical versions of such questions, by examining the number of battle-deaths in the Correlates of War dataset, with 95 interstate wars from 1816 to 2007. Previous research has found this series of wars to be stationary, with no apparent change over time. We develop a framework to find and assess a change-point in this battle-deaths series. Our change-point methodology takes ...
Tópico(s): Terrorism, Counterterrorism, and Political Violence
2020 - SAGE Publishing | Journal of Peace Research
Laura Bojarskaite, Daniel M. Bjørnstad, Klas H. Pettersen, Céline Cunen, Gudmund Horn Hermansen, Knut Sindre Åbjørsbråten, Anna R. Chambers, Rolf Sprengel, Koen Vervaeke, Wannan Tang, Rune Enger, Erlend A. Nagelhus,
Abstract Astrocytic Ca 2+ signaling has been intensively studied in health and disease but has not been quantified during natural sleep. Here, we employ an activity-based algorithm to assess astrocytic Ca 2+ signals in the neocortex of awake and naturally sleeping mice while monitoring neuronal Ca 2+ activity, brain rhythms and behavior. We show that astrocytic Ca 2+ signals exhibit distinct features across the sleep-wake cycle and are reduced during sleep compared to wakefulness. Moreover, an increase ...
Tópico(s): Neuroscience and Neuropharmacology Research
2020 - Nature Portfolio | Nature Communications
Laura Bojarskaite, Alexandra Vallet, Daniel M. Bjørnstad, Kristin M. Gullestad Binder, Céline Cunen, Kjell Heuser, Miroslav Kuchta, Kent‐André Mardal, Rune Enger,
Abstract Perivascular spaces are important highways for fluid and solute transport in the brain enabling efficient waste clearance during sleep. However, the underlying mechanisms augmenting perivascular flow in sleep are unknown. Using two-photon imaging of naturally sleeping male mice we demonstrate sleep cycle-dependent vascular dynamics of pial arteries and penetrating arterioles: slow, large-amplitude oscillations in NREM sleep, a vasodilation in REM sleep, and a vasoconstriction upon awakening ...
Tópico(s): Obstructive Sleep Apnea Research
2023 - Nature Portfolio | Nature Communications
Daniel M. Bjørnstad, Knut Sindre Åbjørsbråten, Eivind Hennestad, Céline Cunen, Gudmund Horn Hermansen, Laura Bojarskaite, Klas H. Pettersen, Koen Vervaeke, Rune Enger,
Imaging the intact brain of awake behaving mice without the dampening effects of anesthesia, has revealed an exceedingly rich repertoire of astrocytic Ca 2+ signals. Analyzing and interpreting such complex signals pose many challenges. Traditional analyses of fluorescent changes typically rely on manually outlined static region-of-interests, but such analyses fail to capture the intricate spatiotemporal patterns of astrocytic Ca 2+ dynamics. Moreover, all astrocytic Ca 2+ imaging data obtained from ...
Tópico(s): Memory and Neural Mechanisms
2021 - Frontiers Media | Frontiers in Cellular Neuroscience
Knut Sindre Åbjørsbråten, Gry HE Syverstad Skaaraas, Céline Cunen, Daniel M. Bjørnstad, Kristin M. Gullestad Binder, Laura Bojarskaite, Vidar R. Jensen, Lars Nilsson, Shreyas Balachandra Rao, Wannan Tang, Gudmund Horn Hermansen, Erlend A. Nagelhus, Ole Petter Ottersen, Reidun Torp, Rune Enger,
Increased astrocytic Ca 2+ signaling has been shown in Alzheimer’s disease mouse models, but to date no reports have characterized behaviorally induced astrocytic Ca 2+ signaling in such mice. Here, we employ an event-based algorithm to assess astrocytic Ca 2+ signals in the neocortex of awake-behaving tg-ArcSwe mice and non-transgenic wildtype littermates while monitoring pupil responses and behavior. We demonstrate an attenuated astrocytic Ca 2+ response to locomotion and an uncoupling of pupil ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2022 - eLife Sciences Publications Ltd | eLife
Lei An, Mengxue Li, Cunen Zou, Ke Wang, Wei Zhang, Xiaolong Huang, Yousheng Wang,
Accumulating evidence has confirmed the health benefits of walnut diets in maintaining brain function with age. Recent studies have indicated that walnut polyphenols (WP) and their active metabolites urolithins may play an important role in the health benefits of walnut diets. In the present study, we evaluated the protective effect of WP and urolithin A (UroA) on H2O2-induced damage in human neuroblastoma (SH-SY5Y) cells, and investigated its mechanisms in the cAMP-response element binding protein ( ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2022 - Royal Society of Chemistry | Food & Function
Cunen Wu, Yuwen Zhuang, Jin‐Yong Zhou, Shenlin Liu, Xi Zou, Jian Wu, Ruiping Wang, Peng Shu,
Abstract The Nm23 gene has been acknowledged to play a crucial role in lung cancer metastasis inhibitory cascades controlled by multiple factors. Low expression or allelic deletion of nm23-H1 is strongly linked to widespread metastasis and poor differentiation of non-small cell lung cancer (NSCLC). In this study, nm23-H1 was down regulated in epithelial-mesenchymal transition (EMT) and stemness enhancement under cobalt chloride (CoCl 2 )-induced hypoxia in NSCLC cells. Moreover, knocking down of nm23- ...
Tópico(s): Polyamine Metabolism and Applications
2019 - De Gruyter | Biological Chemistry
Nicole Borg Cunen, Julie Jomeen, Angela Poat, Rita Borg Xuereb,
The way that expectant parents think and feel about the fetus during pregnancy is thought to be somewhat predictive of their later relationship with the child. However, efforts to identify determinants, correlates and consequences of the parental-fetal tie have had conflicting results. This is likely to be partially attributable to issues in existing conceptualisations of the phenomenon.The purpose of the study was to construct substantive theory of expectant parents' fetal conceptual and relational ...
Tópico(s): Assisted Reproductive Technology and Twin Pregnancy
2021 - Elsevier BV | Midwifery
Céline Cunen, Lars Walløe, Nils Lid Hjort,
A central point of disagreement, in certain long-standing discussions about a particular whaling dataset in the Scientific Committee of the International Whaling Commission, has directly involved model selection issues for linear mixed effect models. The biological question under discussion is associated with a clearly defined parameter of primary interest, a focus parameter, which makes model selection with the Focused Information Criterion (FIC) more appropriate than other selection methods. Since ...
Tópico(s): Genetic and phenotypic traits in livestock
2020 - Institute of Mathematical Statistics | The Annals of Applied Statistics
Gerda Claeskens, Céline Cunen, Nils Lid Hjort,
Datasets encountered when examining deeper issues in ecology and evolution are often complex. This calls for careful strategies for both model building, model selection, and model averaging. Our paper aims at motivating, exhibiting, and further developing focused model selection criteria. In contexts involving precisely formulated interest parameters, these versions of FIC, the focused information criterion, typically lead to better final precision for the most salient estimates, confidence intervals, ...
Tópico(s): Data Analysis with R
2019 - Frontiers Media | Frontiers in Ecology and Evolution
Jin‐Yong Zhou, Cunen Wu, Zhaofeng Shen, Shenlin Liu, Xi Zou, Jun Qian, WU Zhenfeng, Xiangkun Huan, Bai-Xiang Mu, Ningyuan Ye, Yongbo Ning, Yaxing Wang, Min Chen, Yuwen Zhuang,
Complementary treatment with valuable efficacy and less toxic or side effect is in urgent need for colorectal cancer (CRC) therapy. Yiqi Huayu Jiedu Decoction (YHJD) is a polyherbal formulation which has been applied in clinic to treat CRC for a long period of time. Nevertheless, the potential active ingredients and molecular mechanism remains to be further explored.To probe the effective compounds of YHJD and its underlying pharmacological effects. Moreover, the influence on liver metastasis of CRC ...
Tópico(s): Cancer Mechanisms and Therapy
2023 - Elsevier BV | Journal of Ethnopharmacology
Zhichao Jin, Baoxinzi Liu, Bofan Lin, Ran Yang, Cunen Wu, Weiwei Xue, Xi Zou, Jun Qian,
Background The long non-coding RNA (lncRNA) RP9 pseudogene (RP9P) is a pseudogene-derived lncRNA that has never been reported in cancer, and its function underlying tumorigenesis in colorectal cancer (CRC) remains unknown. Methods RP9P and miR-133a-3p were filtered through bioinformatics analysis. The level of RP9P, miR-133a-3p, and FOXQ1 in CRC cell lines was detected by real-time PCR. Cell Counting Kit-8 and flow cytometric analyses were used to detect cell proliferation and apoptosis, respectively. ...
Tópico(s): RNA modifications and cancer
2022 - Frontiers Media | Frontiers in Oncology
Céline Cunen, Nils Lid Hjort, Tore Schweder,
The recent article ‘Satellite conjunction analysis and the false confidence theorem’ (Balch et al . 2019, Satellite conjunction analysis and the false confidence theorem. Proc. R. Soc. A 475 , 20180565) points to certain difficulties with Bayesian analysis when used for models for satellite conjuntion and ensuing operative decisions. Here, we supplement these previous analyses and findings with further insights, uncovering what we perceive of as being the crucial points, explained in a prototype set-up ...
Tópico(s): Target Tracking and Data Fusion in Sensor Networks
2020 - Royal Society | Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences
Cunen Wu, Weiwei Xue, Yuwen Zhuang, Dawei Ding, Jin‐Yong Zhou, Shenlin Liu, Ruiping Wang, Peng Shu,
Gastric cancer (GC) is one of the top 10 malignant tumors worldwide and poses a great threat to human life and health, the prevention and treatment of which has become the focus and difficulty of medical research. With its unique advantages, traditional Chinese medicine (TCM) is widely used in the prevention and treatment of postoperative recurrence and metastasis of GC as well as the improvement of patients' quality of life. The aim of this study is to elucidate the curative effect and the underlying ...
Tópico(s): Cancer-related molecular mechanisms research
2020 - Wolters Kluwer | Medicine
Min Chen, Yuwen Zhuang, Cunen Wu, Haiyan Peng, Jun Qian, Jin‐Yong Zhou,
Studies have revealed that β‑asarone exerts a powerful inhibitory effect on the proliferation of human cancer cells. The authors' previous study demonstrated that β‑asarone could induce LoVo colon cancer cell apoptosis in vitro and in vivo , indicating its anticancer properties. The present study aimed to determine the antineoplastic effect of β‑asarone in HCT116 colon cancer cells. An in vitro proliferation assay using a real time cell analyzer demonstrated that β‑asarone effectively decreased HCT116 ...
Tópico(s): Antimicrobial Peptides and Activities
2021 - Spandidos Publishing | Oncology Letters
Yuwen Zhuang, Jin‐Yong Zhou, Shenlin Liu, Qiong Wang, Jun Qian, Zou Xi, Haiyan Peng, Tian Xue, Zhichao Jin, Cunen Wu,
Colon adenocarcinoma (COAD) accounts for 95% of colon cancer cases, with the 5-year survival rate significantly affected by local or distant metastases. Yiqi Jianpi Huayu Jiedu decoction (YJHJD), based on the theory of "nourish qi, invigorate the spleen, remove blood stasis, and detoxify", has long been applied and shown to be remarkable in the prevention and treatment of gastrointestinal tumors. However, the underlying therapeutic mechanisms of YJHJD have not been fully elucidated. Herein, we first ...
Tópico(s): Ferroptosis and cancer prognosis
2022 - Frontiers Media | Frontiers in Oncology