A. Barberi, Salvatore Cappabianca, G Colella,
... ossifying fibromaMasaya Kawaguchi, Hiroki Kato, Tatsuhiko Miyazaki, Keizo Kato, Daijiro Hatakeyama, Keisuke Mizuta, Mitsuhiro Aoki and Masayuki Matsuo11 ...
Tópico(s): Soft tissue tumor case studies
2003 - Wiley | British Journal of Radiology
Daijiro Kurosaka, Katsuhiko Kato, Hiroyo Kurosaka, Mami Yoshino, Kunihiko Nakamura, Kazuno Negishi,
Purpose: To examine the long-term occurrence and course of Elschnig pearl (string of pearls) formation along neodymium:YAG (Nd:YAG) laser posterior capsulotomy margins. Setting: Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. Methods: The clinical records of eyes having an Nd:YAG posterior capsulotomy to treat posterior capsule opacification after cataract surgery were retrospectively reviewed. Kaplan-Meier and Cox proportional hazards analysis were performed. Results: ...
Tópico(s): Glaucoma and retinal disorders
2002 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Daijiro Kurosaka, Katsuhiko Kato, Toshiyuki Nagamoto,
AIMS: To determine whether alpha smooth muscle actin (alpha-SMA), a marker for myofibroblastic cells, is present in lens epithelial cells (LECs) in rabbit aphakic eyes. METHODS: Phacoemulsification was performed in rabbit eyes, which were enucleated after surgery. Immunohistochemical methods were used to detect alpha-SMA in LECs. RESULTS: Five days after surgery, the presence of alpha-SMA positive LECs was observed mainly around the adhesive portion of the anterior capsule margin and the posterior ...
Tópico(s): Corneal surgery and disorders
1996 - BMJ | British Journal of Ophthalmology
Takeshi Oshima, Daijiro Kurosaka, Keitaro Kato, Hiroyo Kurosaka, Yukihiko Mashima, Yuka Tanaka, S. Tajima,
To determine whether tranilast, N-(3,4-dimethoxycinnamoyl) anthranilic acid, influences cell proliferation and collagen synthesis by rabbit Tenon's capsule fibroblasts (TFs) and corneal stromal fibroblasts (CFs).Rabbit TFs and CFs (7000 cells/well) were cultured in F-12 nutrient mixture supplemented with 1% FBS, plus 0, 3, 30, or 300 microM tranilast, and the number of cells was counted 72 hrs later. To determine the effect of tranilast on collagen synthesis, cells at confluence were cultured in a ...
Tópico(s): Retinoids in leukemia and cellular processes
2000 - Taylor & Francis | Current Eye Research
Daijiro Kurosaka, Katsuhiko Kato,
Purpose: To determine whether intraocular lens (IOL) material influences the membranous proliferation of lens epithelial cells (LECs) on the anterior surface of the IOL. Setting: Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. Methods: This prospective study included 87 eyes of 87 consecutive patients who had cataract surgery with IOL implantation. Patients were randomly assigned to receive a single-piece poly(methyl methacrylate) (PMMA) IOL, a 3-piece silicone IOL, or ...
Tópico(s): Anorectal Disease Treatments and Outcomes
2001 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Daijiro Kurosaka, Katsuhiko Kato, Takeshi Oshima, Hiroyo Kurosaka, Mami Yoshino, Masaro Ogata,
To determine whether extracellular matrix (ECM) influences the expression of alpha-smooth muscle actin (alpha-SMA), a marker for myofibroblasts, in cultured porcine lens epithelial cells (LECs).Porcine LECs were cultured for 6 days in an F-12 nutrient mixture supplemented with 5% fetal bovine serum on wells that were coated with laminin, fibronectin, type I collagen, or type IV collagen. LECs cultured on uncoated wells served as a control. Alpha-SMA was detected immunocytochemically with a mouse monoclonal ...
Tópico(s): Ocular Surface and Contact Lens
1999 - Taylor & Francis | Current Eye Research
Hamizah Shahirah Hamezah, Lina Wati Durani, Nor Faeizah Ibrahim, Daijiro Yanagisawa, Tomoko Kato, Akihiko Shiino, Sachiko Tanaka, Hanafi Ahmad Damanhuri, Wan Zurinah Wan Ngah, Ikuo Tooyama,
Impairments in cognitive and locomotor functions usually occur with advanced age, as do changes in brain volume. This study was conducted to assess changes in brain volume, cognitive and locomotor functions, and oxidative stress levels in middle- to late-aged rats. Forty-four male Sprague-Dawley rats were divided into four groups: 14, 18, 23, and 27 months of age. 1H magnetic resonance imaging (MRI) was performed using a 7.0-Tesla MR scanner system. The volumes of the lateral ventricles, medial prefrontal ...
Tópico(s): Adipose Tissue and Metabolism
2017 - Elsevier BV | Experimental Gerontology
Daijiro Yanagisawa, Tomoko Kato, Hiroyasu Taguchi, Nobuaki Shirai, Koichi Hirao, Takayuki Sogabe, Takami Tomiyama, Keizo Gamo, Yukie Hirahara, Masaaki Kitada, Ikuo Tooyama,
The accumulation of β-amyloid (Aβ) aggregates in the brain occurs early in the progression of Alzheimer's disease (AD), and non-fibrillar soluble Aβ oligomers are particularly neurotoxic. During binding to Aβ fibrils, curcumin, which can exist in an equilibrium state between its keto and enol tautomers, exists predominantly in the enol form, and binding activity of the keto form to Aβ fibrils is much weaker. Here we described the strong binding activity the keto form of curcumin derivative Shiga-Y51 ...
Tópico(s): Drug Transport and Resistance Mechanisms
2021 - Elsevier BV | Biomaterials
Makoto Toida, Yuki Nanya, Tomoko Takeda‐Kawaguchi, Seiji Baba, Kazuki Iida, Keizo Kato, Daijiro Hatakeyama, Hiroki Makita, Tomomi Yamashita, Toshiyuki Shibata,
Recently, oral sensory complaints (OSC) were proposed as a disease entity to represent idiopathic sensory disturbances of dry mouth, burning mouth, and taste disturbance, even though neither the status of OSC in the general population nor its underlying mechanism has yet been elucidated. Moreover, these three OSC-related complaints have not been assessed in combination by means of a visual analog scale (VAS) in a large-scale, community-dwelling population of a broad age range.In a 1188-member community- ...
Tópico(s): Oral Health Pathology and Treatment
2010 - Wiley | Journal of Oral Pathology and Medicine
Keiko Yamada, Toshiyuki Nagamoto, Hisami Yozawa, Katsuhiko Kato, Daijiro Kurosaka, H Miyajima, Chojiro Kimura,
We compared the effect of biconvex and convex-piano (posterior piano) intraocular lenses on posterior capsule opacification (PCO) following continuous curvilinear capsulorhexis (CCC) in 212 eyes. During the three years following surgery, the cumulative frequency of neodymium:YAG laser posterior capsulotomy, calculated with the Kaplan-Meier method, was significantly higher in patients in the biconvex group (32.5% by the third year) than in those in the convex-piano group (5.9% by the third year) (P < .05, ...
Tópico(s): Anesthesia and Pain Management
1995 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Kentaro Kato, Daijiro Konno, Martin Berry, Fumio Matsuzaki, Ann Logan, Alicia Hidalgo,
Central nervous system injury induces a regenerative response in ensheathing glial cells comprising cell proliferation, spontaneous axonal remyelination, and limited functional recovery, but the molecular mechanisms are not fully understood. In Drosophila, this involves the genes prospero and Notch controlling the balance between glial proliferation and differentiation, and manipulating their levels in glia can switch the response to injury from prevention to promotion of repair. In the mouse, Notch1 ...
Tópico(s): MicroRNA in disease regulation
2015 - Public Library of Science | PLoS ONE
Kazuno Negishi, Hiroko Bissen‐Miyajima, K. Kato, Daijiro Kurosaka, Toshiyuki Nagamoto,
Tópico(s): Intraocular Surgery and Lenses
1997 - Elsevier BV | American Journal of Ophthalmology
Katsuhiko Kato, Daijiro Kurosaka, Hiroko Bissen‐Miyajima, Kazuno Negishi, Emiko Hara, Toshiyuki Nagamoto,
To determine the incidence of Elschnig pearl formation along the capsulotomy margin (string of pearls) after neodymium:YAG (Nd:YAG) laser posterior capsulotomy and to elucidate its clinical features, predisposing factors, effect on visual function, and association with additional capsulotomy.Keio University Hospital, Tokyo, Japan.The records of 418 eyes that had had Nd:YAG posterior capsulotomy after cataract surgery were retrospectively reviewed. Of those, 315 were excluded for short follow-up (fewer ...
Tópico(s): Surgical Sutures and Adhesives
1997 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Tsuneo Shimokawa, Kazuhiko Yamada, Hiroshi Tanaka, Kaoru Kubota, Yuichi Takiguchi, Kazuma Kishi, Haruhiro Saito, Yukio Hosomi, Terufumi Kato, Daijiro Harada, Sakiko Otani, Takashi Kasai, Yoichi Nakamura, Toshihiro Misumi, Takeharu Yamanaka, Hiroaki Okamoto,
Abstract Cisplatin‐based chemoradiotherapy is considered standard treatment for unresectable locally advanced non‐small‐cell lung cancer (LA‐NSCLC). This study examined two regimens of chemotherapy in concurrent chemoradiation. Eligible patients with unresectable, radically irradible LA‐NSCLC were randomized to either the SP (S‐1 and cisplatin) or DP (docetaxel and cisplatin) arms with concurrent thoracic radiotherapy of 60 Gy, comprising 2 Gy per daily fraction. The primary endpoint was the overall ...
Tópico(s): Lung Cancer Research Studies
2020 - Wiley | Cancer Medicine
Hiroki Kato, Masayuki Kanematsu, Hiroki Makita, Keizo Kato, Daijiro Hatakeyama, Toshiyuki Shibata, Keisuke Mizuta, Mitsuhiro Aoki,
Palatal tumors commonly arise from the minor salivary glands, and benign tumors account for approximately half of all minor salivary gland tumors. Minor salivary gland tumors have an affinity for the posterior hard palate and soft palate and virtually never arise in the midline, probably because of the distribution of palatal salivary glands. The majority of benign salivary gland tumors of the palate are pleomorphic adenomas, while the most common malignant salivary gland tumor is adenoid cystic ...
Tópico(s): Ear and Head Tumors
2013 - Elsevier BV | European Journal of Radiology
Nguyễn Thành Long, Hiroki Makita, Tomomi Yamashita, Makoto Toida, Keizo Kato, Daijiro Hatakeyama, Toshiyuki Shibata,
The preventive effects of the dietary administration of brown rice and rice bran fermented with Aspergillus oryzae (FBRA) on oral carcinogenesis induced by 4-nitroquinoline 1-oxide (4-NQO) were investigated in male F344 rats. At 7 weeks of age, the animals were given 20 ppm 4-NQO in their drinking water for 8 weeks to induce tongue neoplasms. Groups of rats were fed diets containing 5 or 10% FBRA during the initiation or postinitiation phases of the 4-NQO-induced oral carcinogenesis. The other groups ...
Tópico(s): GABA and Rice Research
2007 - Elsevier BV | Oncology Reports
Masahiko Tomimatsu, Hitoshi Endou, Haruki Takahashi, Daijiro Iga, Yoshikazu Kato, Norio Tamai, Hiroko Nakajima, Akira Okano, Haruki Mori, Hisashi Hisatomi,
In patients receiving interferon therapy for chronic hepatitis C, serum hepatitis C virus (HCV) RNA often reverts from an undetectable to a detectable form after completion of treatment. Detection of the negative strand of HCV-RNA in liver tissue is regarded as an index of viral proliferation. Therefore, we investigated changes in the hepatic negative-strand HCV-RNA following interferon therapy to determine whether this parameter could predict the long-term response to treatment. The subjects of ...
Tópico(s): Hepatitis B Virus Studies
1997 - Wiley | Journal of Gastroenterology and Hepatology
Osamu Kozawa, Hiroyuki Matsuno, Masayuki Niwa, Daijiro Hatakeyama, Yutaka Oiso, Kanefusa Kato, Toshihiko Uematsu,
We previously showed that a dissociated form of a low-molecular-weight heat shock-related protein 20 (HSP20) but not an aggregated form of HSP20 suppresses platelet aggregation. In the present study, we investigated the behavior of HSP20 in response to endothelial injury and the possible mechanism of HSP20 in platelet functions. The levels of HSP20 in vessel wall after endothelial injury were markedly reduced. This observation was supported by the results of Western blotting analysis and immunohistochemical ...
Tópico(s): Thermoregulation and physiological responses
2002 - Elsevier BV | Life Sciences
Ikuo Tooyama, Daijiro Yanagisawa, Hiroyasu Taguchi, Tomoko Kato, Koichi Hirao, Nobuaki Shirai, Takayuki Sogabe, Nor Faeizah Ibrahim, Toshiro Inubushi, Shigehiro Morikawa,
The formation of senile plaques followed by the deposition of amyloid-β is the earliest pathological change in Alzheimer's disease. Thus, the detection of senile plaques remains the most important early diagnostic indicator of Alzheimer's disease. Amyloid imaging is a noninvasive technique for visualizing senile plaques in the brains of Alzheimer's patients using positron emission tomography (PET) or magnetic resonance imaging (MRI). Because fluorine-19 ((19)F) displays an intense nuclear magnetic resonance ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2016 - Elsevier BV | Ageing Research Reviews
Daijiro Kurosaka, Ichiro Ando, Katsuhiko Kato, Takeshi Oshima, Hiroyo Kurosaka, Mami Yoshino, Toshiyuki Nagamoto, Nobuyo Ando,
Purpose: To determine whether the pathogenesis of capsule contraction syndrome involves the outgrowth of the fibrous membrane from the anterior capsule margin. Setting: Department of Ophthalmology, Keio University School of Medicine, Tokyo, and the Ando Eye Clinic, Kanagawa, Japan. Methods: A retrospective review of medical records and slitlamp photographs was conducted in 12 eyes (10 patients) that had required treatment for a narrowed anterior capsule opening after cataract surgery. All patients ...
Tópico(s): Connective tissue disorders research
1999 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Haruhisa Sakamoto, Shinji SHIMIZU, Daijiro KATO,
Loading behaviour of the grinding wheel is investigated based on working surface topography. For on-machine measurement of working surface profile, the laser micrometer is directly fitted on the wheel head of CNC surface grinder. Mild steel (S 15 C) easy to load is ground with an aluminum oxide grinding wheel (WA 60 J 7 V). From the comparison of profile and micro-observation of working surface, the following results are obtained : There are two types of loading ; deposition type loading is caused by ...
Tópico(s): Advanced Surface Polishing Techniques
1998 - | Journal of the Japan Society for Precision Engineering
Masaya Kawaguchi, Hiroki Kato, Tatsuhiko Miyazaki, Keizo Kato, Daijiro Hatakeyama, Keisuke Mizuta, Mitsuhiro Aoki, Masayuki Matsuo,
The current study aimed to assess CT and MRI characteristics of histological subtypes of head and neck ossifying fibroma (OF).12 patients with histopathologically-proven head and neck OF were included in this study. Lesions were pathologically classified into three histological subtypes: eight cement-OFs (COFs), three juvenile psammomatoid OFs (JPOFs), and one juvenile trabecular OF (JTOF). All patients underwent CT examination, while seven also underwent MRI. Imaging characteristics were retrospectively ...
Tópico(s): Soft tissue tumor case studies
2018 - Oxford University Press | Dentomaxillofacial Radiology
Daijiro Yanagisawa, Hiroyasu Taguchi, Shigehiro Morikawa, Tomoko Kato, Koichi Hirao, Nobuaki Shirai, Ikuo Tooyama,
Modulation of abnormal amyloid β (Aβ) aggregation is considered to be a potential therapeutic target for Alzheimer's disease (AD). Recent in vitro and in vivo experiments suggest that inhibition of Aβ aggregation by curcumin would exert favorable effects for preventing or treating AD. We have previously synthesized a series of novel curcumin derivatives. In this study, we investigated the effects of our curcumin derivatives on Aβ aggregation and the cell toxicities of Aβ aggregates. According to sodium ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2015 - Elsevier BV | Biochemistry and Biophysics Reports
Yoshimitsu Kobashi, Daijiro Tanaka, Teppei Maruko, Satoshi Kato, Masato Kishiura, Jiro Senda,
Tópico(s): Catalytic Processes in Materials Science
2011 - | SAE technical papers on CD-ROM/SAE technical paper series
Shintaro Shiba, Noriyuki Okonogi, Shingo Kato, Masaru Wakatsuki, Daijiro Kobayashi, Hiroki Kiyohara, Tatsuya Ohno, Kumiko Karasawa, Takashi Nakano, Tadashi Kamada,
Background/Aim: To evaluate the safety and efficacy of re-irradiation with carbon-ion radiotherapy (C-ion RT) for lymph node recurrence of gynecological cancers after definitive radiotherapy. Patients and Methods: Data regarding patients with unresectable and isolated recurrent lymph node from gynecological cancer after definitive radiotherapy were analyzed. Total dose of C-ion RT was 48-57.6 Gy (RBE) in 12 or 16 fractions. Results: Sixteen patients received re-irradiation by C-ion RT were analyzed. ...
Tópico(s): Colorectal and Anal Carcinomas
2017 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
Noriyuki Okonogi, Masaru Wakatsuki, Shingo Kato, Shintaro Shiba, Daijiro Kobayashi, Hiroki Kiyohara, Kumiko Karasawa, Tatsuya Ohno, Takashi Nakano, Tadashi Kamada, Makio Shozu,
Background/Aim: To evaluate the long-term outcomes of carbon-ion radiotherapy (C-ion RT) for locally advanced cervical squamous cell carcinoma (LAC-SqCC) in 2 prospective phase I/II studies. Patients and Methods: In the first study, 14 patients were treated with 68.8-72.8 Gy (RBE)/24 fractions. In a subsequent study, 22 patients were treated with 64.0-72.0 Gy (RBE)/20 fractions while limiting the dose to the gastro-intestinal (GI) <60 Gy (RBE). Results: The 10-year local control rates were 92% and 61% ...
Tópico(s): Head and Neck Cancer Studies
2018 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
Keikichi Uchida, Daijiro Ohmorib, Yuki Eshita, Tsutomu Oda, Yukio Kato, Kyoko Tomizawa, A. Moribayashi, Akihiro Fukunaga,
Infusion of 20-hydroxyecdysone into the hemocoel of unfed decapitated female Culex pipiens pallens mosquitoes, at a very low rate of 500-2000pg per day, often stimulated oögenesis of this species, when the hormone was infused together with amino acids. The hormone alone or amino acids alone showed no such stimulatory effect. Previous reports that using an abdomen ligated immediately after a blood meal for hormone injection reduced the quantity of 20-hydroxyecdysone needed to activate unfed female ...
Tópico(s): Neurobiology and Insect Physiology Research
1998 - Elsevier BV | Journal of Insect Physiology
Osamu Kozawa, Masayuki Niwa, Daijiro Hatakeyama, Haruhiko Tokuda, Yutaka Oiso, Hiroyuki Matsuno, Kanefusa Kato, Toshihiko Uematsu,
Abstract It is generally recognized that osteoporosis is a common complication of patients with glucocorticoid excess and that glucocorticoid receptor is associated with heat shock protein (HSP) 70 and HSP90 in a heterocomplex. In the present study, we investigated whether glucocorticoid induces HSP27, HSP70, and HSP90 in osteoblast‐like MC3T3‐E1 cells. Dexamethasone time‐dependently increased the levels of HSP27, while having no effect on the levels of HSP70 or HSP90. The effect of dexamethasone ...
Tópico(s): Heat shock proteins research
2002 - Wiley | Journal of Cellular Biochemistry
Xiaodan Wang, Haruhiko Tokuda, Daijiro Hatakeyama, Kouseki Hirade, Masayuki Niwa, Hidenori Ito, Kanefusa Kato, Osamu Kozawa,
It has recently been reported that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) stimulate bone formation. However, the mechanism of stimulation of bone metabolism by statins is not precisely clarified. In this study, we investigated whether simvastatin induces heat shock protein (HSP) 27, HSP70, and HSP90 in osteoblast-like MC3T3-E1 cells. Simvastatin increased the levels of HSP27 while having little effect on the levels of HSP70 or HSP90. The effect of simvastatin on HSP27 ...
Tópico(s): Calpain Protease Function and Regulation
2003 - Elsevier BV | Archives of Biochemistry and Biophysics
Daijiro Sato, Kahoru Obara, Youhei Kawabata, Makio Iwahashi, Tadashi Kato,
We have found for the first time the reentrant lamellar/onion (lamellar–onion–lamellar) transition with varying temperature under constant shear rate by using simultaneous measurements of shear stress and small-angle X-ray scattering (Rheo-SAXS) for a nonionic surfactant (C14E5)/water system, which exhibits the lamellar phase in a wide temperature range from 15–75 °C. The onion state exists in a closed region in the temperature–concentration diagram at a constant shear rate. Temperature dependence of ...
Tópico(s): Surfactants and Colloidal Systems
2012 - American Chemical Society | Langmuir