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Peter Goodchild, Manila, Malcolm Brown, Barbara Hall, Will Ellsworth-Jones, John Jay City Editor, John Davison, Mario Modiano Athens, Jon Swain, Catherine Bennett, Chris Ryder, Rob Hughes, John Peter, Julian Chomet, Mark Reason, Liz Sly, Eric Dymock, Jill Hartley, Christopher Smallwood Economics Editor, John Jay, John Diamond, Neville Hodgkinson Medical Correspondent, Graham Rose, Ivan Fallon Deputy Editor, Sally Payne, Tana de Zuelueta, Julian Symons, Russell Taylor, Frederic Raphael, Henry Porter, Jason Tomas, John Grice, Uri Geller, Charles Kendall, Caroline Baker, John Westwell, Jon Craig, Judi Bevan Deputy City Editor, Patrick Stoddart, Susan Marling, Beirut, Alex Sutherland, Iain Johnstone, Robert Sandall, John Major, Irwin Stelzer, John Newell, Peter Godwin, Peter Wilson, Bernard Levin, Deryk Brown, Mick Brown, David Dougill, Ivan Fallon, John Mortimer, Jane Bird, Ian MacLeay, Anna Raeburn, Andrew Dickson, Gerry Woolf, David Cairns, Anne Jacobs, David Connett, Geoff Whitten, John Cassidy, Sue Mott, Byron Rogers, John Heath-Stubbs, Sir Roy Strong, Christine Toomey, Bernard Cafferty, Paul McFarland, R Turner, Nigella Lawson, Sir Ralph Halpern, James Bishop Editor, Tim Haines, David Leppard, Tim Rayment, Annie Topham, Adam Ruck, David Lawrenson, John Hopkins, Judi Bevan, Brian Walden, Eric Marsden, Rodney Milnes Editor, Steve Taylor, Brian Reading, Stephen Pile, Nicosia, Liz Jobey Editor, Marie Colvin, Diana Wright, Christopher Smallwood, Ali Ross, Stephen Jones, Colin Thorpe, Desmond Shawe-Taylor, Susan, Brian Deer, Richard Palmer, Keith Wheatley, Lin Neumann, Patrick Rowley, Bruce Kemble Education Correspondent, Stephen Davis, Dilys Powell, B. G. Eke, Caroline McGhie, Clive Everton, Tony Osman, Richard Woods, Louise Branson, Max Prangnell, Maurice Chittenden, Iola Smith, Dudley Doust, Ian Dunning, David Hughes Political Correspondent, Michael Jones Political Editor, Mihir Bose, Philip Beresford, Tony Adams, Richard Burnell, Charles Oulton, Kilbracken, Brian Glanville, Andrew Collier, Alan Jenkins, David White, Tim McGirk, Simon Jenkins, Chris Ryder Cork, Katharine Hamnett, Hugh Thompson, Simon Rose, Nicola, Hilary MacKenzie, Helen Mason, Ottawa, Steve Turner, Marina Vaizey, Chris Lightbown, Alexander MacLeod, James Danziger, Cape Town, Danica Ognjenovic, Margaret Park, Hugh Sebag-Montefiore, Penny Perrick, Tony Hetherington, Jim Muir, Ian Bailey, Clement Freud, Jon Connell, Boris Schapiro, Jane Bird Computer Correspondent,

... was he pushed, persuaded or simply being pragmatic? Patrick Stoddart reports on the director-general's demise ...

1987 - Gale Group | Sunday Times HA GDA

Artigo Revisado por pares

Sally Ross, Lynn L. Ridinger, Jacquelyn Cuneen,

... Fisher are discussed and compared to that of Danica Patrick, a media star in the Indy Racing League ( ...

Tópico(s): Sport and Mega-Event Impacts

2009 - Emerald Publishing Limited | International Journal of Sports Marketing and Sponsorship

Artigo Acesso aberto Revisado por pares

Michael O’Sullivan, Pierre Friedlingstein, Stephen Sitch, Peter Anthoni, Almut Arneth, Vivek K. Arora, Vladislav Bastrikov, Christine Delire, Daniel S. Goll, Atul K. Jain, Etsushi Kato, Daniel Kennedy, Jürgen Knauer, Sebastian Lienert, Danica Lombardozzi, Patrick McGuire, Joe R. Melton, Julia E. M. S. Nabel, Julia Pongratz, Benjamin Poulter, Roland Séférian, Hanqin Tian, Nicolas Vuichard, Anthony P. Walker, Wenping Yuan, Xu Yue, Sönke Zaehle,

Abstract The observed global net land carbon sink is captured by current land models. All models agree that atmospheric CO 2 and nitrogen deposition driven gains in carbon stocks are partially offset by climate and land-use and land-cover change (LULCC) losses. However, there is a lack of consensus in the partitioning of the sink between vegetation and soil, where models do not even agree on the direction of change in carbon stocks over the past 60 years. This uncertainty is driven by plant productivity, ...

Tópico(s): Soil Carbon and Nitrogen Dynamics

2022 - Nature Portfolio | Nature Communications

Artigo Acesso aberto Revisado por pares

Zichong Chen, Junjie Liu, Daven K. Henze, D. N. Huntzinger, Kelley C. Wells, Stephen Sitch, Pierre Friedlingstein, Émilie Joetzjer, Vladislav Bastrikov, Daniel S. Goll, Vanessa Haverd, Atul K. Jain, Etsushi Kato, Sebastian Lienert, Danica Lombardozzi, Patrick McGuire, Joe R. Melton, Julia E. M. S. Nabel, Benjamin Poulter, Hanqin Tian, A. Wiltshire, Sönke Zaehle, Scot M. Miller,

Abstract. Observations from the Orbiting Carbon Observatory 2 (OCO-2) satellite have been used to estimate CO2 fluxes in many regions of the globe and provide new insight into the global carbon cycle. The objective of this study is to infer the relationships between patterns in OCO-2 observations and environmental drivers (e.g., temperature, precipitation) and therefore inform a process understanding of carbon fluxes using OCO-2. We use a multiple regression and inverse model, and the regression coefficients ...

Tópico(s): Science and Climate Studies

2021 - Copernicus Publications | Atmospheric chemistry and physics

Artigo Acesso aberto Revisado por pares

Lina Teckentrup, Martin G. De Kauwe, A. J. Pitman, Daniel S. Goll, Vanessa Haverd, Atul K. Jain, Émilie Joetzjer, Etsushi Kato, Sebastian Lienert, Danica Lombardozzi, Patrick McGuire, Joe R. Melton, Julia E. M. S. Nabel, Julia Pongratz, Stephen Sitch, Anthony P. Walker, Sönke Zaehle,

Abstract. Australia plays an important role in the global terrestrial carbon cycle on inter-annual timescales. While the Australian continent is included in global assessments of the carbon cycle such as the global carbon budget, the performance of dynamic global vegetation models (DGVMs) over Australia has rarely been evaluated. We assessed simulations of net biome production (NBP) and the carbon stored in vegetation between 1901 to 2018 from 13 DGVMs (TRENDY v8 ensemble). We focused our analysis ...

Tópico(s): Plant Water Relations and Carbon Dynamics

2021 - Copernicus Publications | Biogeosciences

Artigo Acesso aberto Revisado por pares

Zichong Chen, D. N. Huntzinger, Junjie Liu, Shilong Piao, Xuhui Wang, Stephen Sitch, Pierre Friedlingstein, Peter Anthoni, Almut Arneth, Vladislav Bastrikov, Daniel S. Goll, Vanessa Haverd, Atul K. Jain, Émilie Joetzjer, Etsushi Kato, Sebastian Lienert, Danica Lombardozzi, Patrick McGuire, Joe R. Melton, Julia E. M. S. Nabel, Julia Pongratz, Benjamin Poulter, Hanqin Tian, A. Wiltshire, Sönke Zaehle, Scot M. Miller,

Abstract Year-to-year variability in CO 2 fluxes can yield insight into climate-carbon cycle relationships, a fundamental yet uncertain aspect of the terrestrial carbon cycle. In this study, we use global observations from NASA’s Orbiting Carbon Observatory-2 (OCO-2) satellite for years 2015–2019 and a geostatistical inverse model to evaluate 5 years of interannual variability (IAV) in CO 2 fluxes and its relationships with environmental drivers. OCO-2 launched in late 2014, and we specifically evaluate ...

Tópico(s): Atmospheric chemistry and aerosols

2021 - IOP Publishing | Environmental Research Letters

Artigo Acesso aberto Revisado por pares

Donald F. Dansereau, Danica K. Knight, Patrick M. Flynn,

Human judgment and decision making (JDM) has substantial room for improvement, especially among adolescents. Increased technological and social complexity "ups the ante" for developing impactful JDM interventions and aids. Current explanatory advances in this field emphasize dual processing models that incorporate both experiential and analytic processing systems. According to these models, judgment and decisions based on the experiential system are rapid and stem from automatic reference to previously ...

Tópico(s): Leadership, Behavior, and Decision-Making Studies

2013 - American Psychological Association | Professional Psychology Research and Practice

Artigo Acesso aberto Revisado por pares

Jennifer E. Becan, Danica K. Knight, Patrick M. Flynn,

One of the unique contributions of this study is a glimpse into the process by which counselors decide to try new innovations in their clinical work. Data were collected from 421 counseling staff from 71 outpatient treatment programs in 4 U.S. regions. Using hierarchical linear modeling, results reveal that the propensity to adopt workshop-based interventions is facilitated by two important mechanisms: (a) an innovative organization with creative leadership and (b) change-oriented staff attributes ( ...

Tópico(s): Counseling Practices and Supervision

2011 - Elsevier BV | Journal of Substance Abuse Treatment

Revisão Acesso aberto Revisado por pares

Wayne E. K. Lehman, D. Dwayne Simpson, Danica K. Knight, Patrick M. Flynn,

Sustained and effective use of evidence-based practices in substance abuse treatment services faces both clinical and contextual challenges. Implementation approaches are reviewed that rely on variations of plan-do-study-act (PDSA) cycles, but most emphasize conceptual identification of core components for system change strategies. A two-phase procedural approach is therefore presented based on the integration of Texas Christian University (TCU) models and related resources for improving treatment ...

Tópico(s): Mental Health and Patient Involvement

2011 - American Psychological Association | Psychology of Addictive Behaviors

Artigo Acesso aberto Revisado por pares

Brittany Landrum, Danica K. Knight, Patrick M. Flynn,

This article explores the impact of organizational attributes on client engagement within substance abuse treatment. Previous research has identified organizational features, including small size, accreditation, and workplace practices, that impact client engagement (K. M. Broome, P. M. Flynn, D. K. Knight, & D. D. Simpson, 2007). This study sought to explore how aspects of the work environment impact client engagement. The sample included 89 programs located in 9 states across the United States. Work ...

Tópico(s): Health Policy Implementation Science

2011 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Acesso aberto Revisado por pares

Wolfgang A. Obermeier, Julia E. M. S. Nabel, Tammas Loughran, Kerstin Hartung, Ana Bastos, Felix Havermann, Peter Anthoni, Almut Arneth, Daniel S. Goll, Sebastian Lienert, Danica Lombardozzi, Sebastiaan Luyssaert, Patrick McGuire, Joe R. Melton, Benjamin Poulter, Stephen Sitch, Michael O. Sullivan, Hanqin Tian, Anthony P. Walker, A. Wiltshire, Sönke Zaehle, Julia Pongratz,

Abstract. Quantifying the net carbon flux from land use and land cover changes (fLULCC) is critical for understanding the global carbon cycle and, hence, to support climate change mitigation. However, large-scale fLULCC is not directly measurable and has to be inferred from models instead, such as semi-empirical bookkeeping models and process-based dynamic global vegetation models (DGVMs). By definition, fLULCC estimates are not directly comparable between these two different model types. As an important ...

Tópico(s): Plant Water Relations and Carbon Dynamics

2021 - Copernicus Publications | Earth System Dynamics

Artigo Acesso aberto Revisado por pares

Pierre Friedlingstein, Matthew W. Jones, Michael O’Sullivan, Robbie M. Andrew, Judith Hauck, Glen P. Peters, Wouter Peters, Julia Pongratz, Stephen Sitch, Corinne Le Quéré, Dorothée C. E. Bakker, Josep G. Canadell, Philippe Ciais, Robert B. Jackson, Peter Anthoni, Leticia Barbero, Ana Bastos, Vladislav Bastrikov, Meike Becker, Laurent Bopp, Erik T. Buitenhuis, Naveen Chandra, Frédéric Chevallier, Louise Chini, Kim Currie, Richard A. Feely, Marion Gehlen, Dennis Gilfillan, Thanos Gkritzalis, Daniel S. Goll, Nicolas Gruber, Sören Gutekunst, Ian Harris, Vanessa Haverd, R. A. Houghton, G. C. Hurtt, Tatiana Ilyina, Atul K. Jain, Émilie Joetzjer, Jed O. Kaplan, Etsushi Kato, Kees Klein Goldewijk, Jan Ivar Korsbakken, Peter Landschützer, Siv K. Lauvset, Nathalie Lefèvre, Andrew Lenton, Sebastian Lienert, Danica Lombardozzi, Gregg Marland, Patrick McGuire, Joe R. Melton, Nicolas Metzl, David R. Munro, Julia E. M. S. Nabel, Shin‐Ichiro Nakaoka, Craig Neill, Abdirahman M Omar, Tsuneo Ono, Anna Peregon, Denis Pierrot, Benjamin Poulter, Gregor Rehder, Laure Resplandy, Eddy Robertson, Christian Rödenbeck, Roland Séférian, Jörg Schwinger, Naomi Smith, Pieter P. Tans, Hanqin Tian, Bronte Tilbrook, Francesco N. Tubiello, Guido R. van der Werf, A. Wiltshire, Sönke Zaehle,

Abstract. Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere – the “global carbon budget” – is important to better understand the global carbon cycle, support the development of climate policies, and project future climate change. Here we describe data sets and methodology to quantify the five major components of the global carbon budget and their uncertainties. Fossil CO2 emissions (EFF) are based on energy ...

Tópico(s): Carbon Dioxide Capture Technologies

2019 - Copernicus Publications | Earth system science data

Artigo Acesso aberto Revisado por pares

Wayne E. K. Lehman, Jennifer E. Becan, George W. Joe, Danica K. Knight, Patrick M. Flynn,

The exposure to new clinical interventions through formalized training and the utilization of strategies learned through training are two critical components of the program change process. This study considers the combined influence of actual program fiscal resources and counselors' perceptions of workplace resources on two mechanisms of training: exposure and utilization. Data were collected from 323 counselors nested within 59 programs located in nine states. Multilevel analysis revealed that ...

Tópico(s): Healthcare Policy and Management

2011 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Acesso aberto

Michael Santucci,

... Yo Ma that what they do is recreation. Danica Patrick is not driving for recreation, either. This is ...

Tópico(s): Musicians’ Health and Performance

2010 - Lippincott Williams & Wilkins | The Hearing Journal

Artigo Acesso aberto Revisado por pares

Danica J. Stark, Kimberly Fornace, Patrick M. Brock, Tommy Rowel Abidin, Lauren J. Gilhooly, Cyrlen Jalius, Benoît Goossens, Chris Drakeley, Milena Salgado‐Lynn,

Land-use changes can impact infectious disease transmission by increasing spatial overlap between people and wildlife disease reservoirs. In Malaysian Borneo, increases in human infections by the zoonotic malaria Plasmodium knowlesi are hypothesised to be due to increasing contact between people and macaques due to deforestation. To explore how macaque responses to environmental change impact disease risks, we analysed movement of a GPS-collared long-tailed macaque in a knowlesi-endemic area in ...

Tópico(s): Wildlife Ecology and Conservation

2019 - Springer Science+Business Media | EcoHealth

Artigo Acesso aberto Revisado por pares

Jennifer R. Edwards, Danica K. Knight, Patrick M. Flynn,

Tópico(s): Substance Abuse Treatment and Outcomes

2010 - Springer Science+Business Media | The Journal of Behavioral Health Services & Research

Artigo Acesso aberto Revisado por pares

Danica K. Knight, Thomas R. Blue, Patrick M. Flynn, Kevin Knight,

The TCU Drug Screen II, a widely used instrument for identifying substance use problems, was originally developed based on Diagnostic and Statistical Manual of Mental Disorders III-R criteria. In 2013, the American Psychiatric Association revised the criteria and classification scheme for substance use disorders (SUDs) with the publication of the DSM-5. Subsequently, the TCU Drug Screen was modified to reflect the updated DSM-5. The current study examines the concordance of the TCU Drug Screen II ...

Tópico(s): Child and Adolescent Psychosocial and Emotional Development

2018 - Taylor & Francis | Journal of Offender Rehabilitation

Artigo Acesso aberto Revisado por pares

George W. Joe, Danica K. Knight, Jennifer E. Becan, Patrick M. Flynn,

Recovery among adolescents undergoing substance abuse treatment was modeled in terms of pretreatment motivation, therapeutic relationships, psychological functioning, treatment retention, legal pressures, DSM diagnoses, and client demographics.To address between program differences, a within-covariance matrix, based on 547 youth, was used.Applicability of the results across treatment modalities was also examined.The data were from the NIDA-sponsored DATOS Adolescent study.Results from structural ...

Tópico(s): Child Welfare and Adoption

2013 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Acesso aberto Revisado por pares

Danica K. Knight, Jennifer E. Becan, Patrick M. Flynn,

The purpose of this study was to examine the impact of staff turnover on perceptions of organizational demands and support among staff who remained employed in substance abuse treatment programs. The sample consisted of 353 clinical staff from 63 outpatient agencies. Two scales from the Survey of Organizational Functioning measured work environment demands (stress and inadequate staffing), and 3 measured supportive work relationships (communication, cohesion, and peer collaboration). Results from ...

Tópico(s): Mentoring and Academic Development

2011 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Acesso aberto Revisado por pares

Danica K. Knight, Jennifer R. Edwards, Patrick M. Flynn,

In Brief The current study examines patterns and predictors of change over a 2-year period in whether outpatient core and wraparound services are offered on-site or by referral. A sample of 69 outpatient nonmethadone programs from 4 US regions provided organizational information across a 2-year period. Services provided within outpatient substance abuse programs were relatively stable over time, particularly with regard to core therapeutic services. The use of referral networks to provide a broader ...

Tópico(s): Healthcare Policy and Management

2010 - Lippincott Williams & Wilkins | Journal of Public Health Management and Practice

Artigo Acesso aberto Revisado por pares

Jennifer R. Edwards, Danica K. Knight, Kirk M. Broome, Patrick M. Flynn,

Directors in substance use treatment programs are increasingly required to respond to external economic and socio-political pressures. Leadership practices that promote innovation can help offset these challenges. Using focus groups, factor analysis, and validation instruments, the current study developed and established psychometrics for the Survey of Transformational Leadership. In 2008, clinical directors were evaluated on leadership practices by 214 counselors within 57 programs in four U.S. ...

Tópico(s): Community Health and Development

2010 - Taylor & Francis | Substance Use & Misuse

Artigo Acesso aberto Revisado por pares

Kirk M. Broome, Danica K. Knight, Jennifer R. Edwards, Patrick M. Flynn,

Counselors are a critical component of substance abuse treatment programming, but their working experiences are not yet well understood. As treatment improvement efforts focus increasingly on these individuals, their perceptions of program leadership, emotional burnout, and job satisfaction and related attitudes take on greater significance. This study explores counselor views and the impact of organizational context using data from a nationwide set of 94 outpatient drug-free treatment programs ...

Tópico(s): Health Policy Implementation Science

2009 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Acesso aberto Revisado por pares

James E. Longbotham, Cynthia M. Chio, Venkatasubramanian Dharmarajan, Michael J. Trnka, Idelisse Ortiz Torres, Devrishi Goswami, Karen Ruiz, Alma L. Burlingame, Patrick R. Griffin, Danica Galonić Fujimori,

Histone demethylase KDM5A removes methyl marks from lysine 4 of histone H3 and is often overexpressed in cancer. The in vitro demethylase activity of KDM5A is allosterically enhanced by binding of its product, unmodified H3 peptides, to its PHD1 reader domain. However, the molecular basis of this allosteric enhancement is unclear. Here we show that saturation of the PHD1 domain by the H3 N-terminal tail peptides stabilizes binding of the substrate to the catalytic domain and improves the catalytic ...

Tópico(s): Cancer-related gene regulation

2019 - Nature Portfolio | Nature Communications

Artigo Acesso aberto Revisado por pares

Kirk M. Broome, Patrick M. Flynn, Danica K. Knight, D. Dwayne Simpson,

A key goal of drug abuse treatment providers is getting their clients to engage and participate in therapeutic activities as a first step toward deriving longer-term benefits. Much research had focused on personal characteristics that relate to client engagement; program characteristics have received less attention. This study explored client and program differences in engagement ratings using data from a nationwide set of 94 outpatient drug-free treatment programs in a hierarchical linear model ...

Tópico(s): Primary Care and Health Outcomes

2007 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Acesso aberto Revisado por pares

Christine F. Skibola, Paige M. Bracci, Eran Halperin, Alexandra Nieters, Alan Hubbard, Randi A. Paynter, Danica R. Skibola, Luz Agana, Nikolaus Becker, Patrick Tressler, Matthew S. Forrest, Sriram Sankararaman, Lucía Conde, Elizabeth A. Holly, Martyn T. Smith,

Background Non-Hodgkin lymphoma (NHL) is the fifth most common cancer in the U.S. and few causes have been identified. Genetic association studies may help identify environmental risk factors and enhance our understanding of disease mechanisms. Methodology/Principal Findings 768 coding and haplotype tagging SNPs in 146 genes were examined using Illumina GoldenGate technology in a large population-based case-control study of NHL in the San Francisco Bay Area (1,292 cases 1,375 controls are included ...

Tópico(s): Acute Lymphoblastic Leukemia research

2008 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Revisado por pares

Zhenkun Na, Yang Luo, Danica S. Cui, Alexandra Khitun, Stephanie Smelyansky, J. Patrick Loria, Sarah A. Slavoff,

Proteogenomic identification of translated small open reading frames in humans has revealed thousands of microproteins, or polypeptides of fewer than 100 amino acids, that were previously invisible to geneticists. Hundreds of microproteins have been shown to be essential for cell growth and proliferation, and many regulate macromolecular complexes. However, the vast majority of microproteins remain functionally uncharacterized, and many lack secondary structure and exhibit limited evolutionary conservation. ...

Tópico(s): RNA and protein synthesis mechanisms

2021 - American Chemical Society | Journal of the American Chemical Society

Artigo Acesso aberto Revisado por pares

Danica K. Knight, Brittany Landrum, Jennifer E. Becan, Patrick M. Flynn,

Although evidence suggests that turnover rates are higher in high-stress/high-needs work environments, it is unclear whether agencies' attempts at improving practices influence individuals' decisions to stay at or leave a job. The purpose of this study was to examine whether program needs and change orientation influence individual decisions to quit. A sample of 206 counselors from 25 outpatient substance abuse treatment programs completed the Survey of Organizational Functioning, rating the organization ...

Tópico(s): Workplace Health and Well-being

2011 - Elsevier BV | Journal of Substance Abuse Treatment

Artigo Revisado por pares

Patrick M. Flynn, Danica K. Knight, Mark D. Godley, Hannah K. Knudsen,

Substance abuse treatment programs represent complex human activity systems in which multiple actors, including clients, counselors, and managers, are nested. Furthermore, treatment programs are nested within the broader environmental context of resource allocation and regulatory enforcement. This special issue of the Journal of Substance Abuse Treatment presents 12 empirical papers that address organizational dynamics within specialty treatment programs. In this introduction to the special issue, ...

Tópico(s): Substance Abuse Treatment and Outcomes

2011 - Elsevier BV | Journal of Substance Abuse Treatment