Mark V. Roehling, Wendy R. Boswell, Paula Caligiuri, Daniel Feldman, Mary Graham, James P. Guthrie, Motohiro Morishima, Judith W. Tansky,
Abstract The contributors to this special issue provide unique perspectives and insights about the future of human resource management, and many of their ideas present opportunities for future research. Our intent is to focus on identifying and briefly discussing the key needs and directions suggested by these articles. The discussion is organized around four general themes: the HR function and its impact, the roles of HR professionals, the value of HR competencies, and the HR implications of globalization. © ...
Tópico(s): International Student and Expatriate Challenges
2005 - Wiley | Human Resource Management
Barry M. Katzman, Stephanie Silberberg, Daniel A. Caligiuri, David M. Klein, Peter DiPaolo,
... M Katzman, MD, , , MD Stephanie Silberberg, MD, , , MD Daniel A Caligiuri, MD, , , MD David M Klein, MD, , and , MD ... MD Barry M Katzman, MD , Stephanie Silberberg, MD , Daniel A Caligiuri, MD , David M Klein, MD , and Peter DiPaolo, ...
1997 - Slack Incorporated (United States) | Orthopedics
Humberto Lamdán, Garcia-Lazaro Rocio Soledad, N. Alcorta Lorenzo, Lorena G. Caligiuri, Daniel F. Alonso, Hernán G. Fariña,
Summary. Background: Blueberries are among the fruits with the highest antioxidant activity and have been recognized by their health promoting properties. Aim: In vitro study of the anti-proliferative effects of a blueberry extract on a panel of cancer cells from different origin. Materials and Methods: A blueberry extract was produced using ethanol as extracting solvent. The anti-proliferative activity of the extract was evaluated against seven tumor cell lines. The properties of blueberry extract ...
Tópico(s): Plant tissue culture and regeneration
2020 - | Experimental Oncology
Barry M. Katzman, David M. Klein, Tom C. Garven, Daniel A. Caligiuri, John Kung,
Twenty annular and 12 cruciform pulleys were dissected from four unembalmed fresh cadaveric fingers and stained with haematoxylin and eosin, Verhoeff-van Gieson stain for elastin, alcian blue stain for hyaluronic acid, and a separate stain for S-100 to identify chondroid cells. Three distinct layers were identified in both annular and cruciform pulleys: an outer layer of fibrofatty tissue with vascular channels outermost, an inner layer of hyaluronic acid-secreting cells, and a collagen-rich layer ...
Tópico(s): Nail Diseases and Treatments
1999 - SAGE Publishing | Journal of Hand Surgery (European Volume)
Barry M. Katzman, David M. Klein, Joseph A. Mesa, Jeffrey A. Geller, Daniel A. Caligiuri,
Since the mallet finger that is treated with isolated splinting of the distal interphalangeal (DIP) joint can be moved freely proximal to the DIP joint, we sought to determine whether such motion might cause a tendon gap that could explain the extensor lag that often follows treatment. Experiments were performed on 32 cadaveric fingers with open mallet finger lesions, immobilizing either the DIP joint alone or both the DIP and PIP joints, while repeatedly flexing and extending the more proximal finger ...
Tópico(s): Musculoskeletal synovial abnormalities and treatments
1999 - SAGE Publishing | Journal of Hand Surgery (European Volume)
David M. Klein, Barry M. Katzman, Joseph A. Mesa, Jeffrey F. Lipton, Daniel A. Caligiuri,
The extensor retinaculum of the wrist has been used for reconstruction of the annular pulleys of the flexor sheath. We examined the histologic structure of the extensor retinaculum and tendon sheath of the wrist and ankle in cadaveric specimens using hematoxylin-eosin and Verhoeff-van Gieson stains to detect elastin and alcian blue to detect hyaluronic acid, comparing the structure with that described previously for the annular pulleys. Three distinct layers are identified in the retinaculums of ...
Tópico(s): Elbow and Forearm Trauma Treatment
1999 - Elsevier BV | The Journal Of Hand Surgery
Barry M. Katzman, Daniel A. Caligiuri, David M. Klein, John M. Gorup,
R upture of the distal biceps brachii is a relatively uncommon injury. Despite its rarity, many treatment methods have been described. Most common is the anatomic restoration of the biceps tendon to the tuberosity. Early reports of iatrogenic radial nerve injury with this technique made surgeons rethink their surgical approach to this problem.4,6,9 In fact, some authors have advocated suturing the biceps brachii to the brachialis, thereby avoiding the risk of nerve injury.4, 9 In 1985, however, ...
Tópico(s): Shoulder Injury and Treatment
1997 - Elsevier BV | Journal of Shoulder and Elbow Surgery
Barry M. Katzman, Daniel A. Caligiuri, David M. Klein, Anthony D. Nicastri, Ping-jiao Chen,
We report a case of recurrent intravascular papillary endothelial hyperplasia.
Tópico(s): Occupational and environmental lung diseases
1997 - SAGE Publishing | Journal of Hand Surgery (European Volume)
Barry M. Katzman, David M. Klein, Tom C. Garven, Daniel A. Caligiuri, John Kung, Evan D. Collins,
Since the anatomy and actual existence of the A5 pulley have been variably reported in the literature, we sought to better define its macroscopic and microscopic structure. Thirty-one A5 pulleys were dissected from 32 fingers. The average proximal to distal length was 3.8 mm; the average width was 8.9 mm. The distal edge of the pulley was proximal to the distal interphalangeal joint, 7.7 mm from the profundus tendon insertion. On histologic study by light microscopy, 3 distinct layers were noted; ...
Tópico(s): Nail Diseases and Treatments
1998 - Elsevier BV | The Journal Of Hand Surgery
Barry M. Katzman, Daniel A. Caligiuri, David M. Klein, Gregory Perrier, Phillip A. Dauterman,
A case is presented where flexor tenosynovitis of the volar wrist is the presenting symptom of sarcoidosis in a 69-year-old man. A case is presented where flexor tenosynovitis of the volar wrist is the presenting symptom of sarcoidosis in a 69-year-old man.
Tópico(s): Sarcoidosis and Beryllium Toxicity Research
1997 - Elsevier BV | The Journal Of Hand Surgery
David M. Klein, Daniel A. Caligiuri, Joseph Riina, Barry M. Katzman,
This case report describes the spontaneous healing of a 20-cm massive tibial cortical defect. The defect was created during debridement of necrotic bone and soft tissue in a low-velocity gunshot wound of the tibia that became infected in a skeletally mature patient. The patient was treated in an external fixator and had a soleus flap to provide soft-tissue coverage. He had refused any surgical reconstructive options. Despite the absence of surgical reconstruction, his tibia healed, and he returned ...
Tópico(s): Hemostasis and retained surgical items
1997 - Lippincott Williams & Wilkins | Journal of Orthopaedic Trauma
Jennifer Kung, S. TOULIOPOLIS, Daniel A. Caligiuri,
We report a patient with an irreducible dislocation of the proximal interphalangeal joint which was due to entrapment of the head of the proximal phalanx in the opening of the flexor digitorum superficialis tendon just proximal to its chiasma.
Tópico(s): Shoulder Injury and Treatment
1998 - SAGE Publishing | Journal of Hand Surgery (European Volume)
Charles G. Schmidt, R. Caligiuri, Lawrence E. Eiselstein, S. S. Wing, Daniel Cubicciotti,
Tópico(s): Advanced Welding Techniques Analysis
1987 - Springer Science+Business Media | Metallurgical Transactions A
Álvaro Proaño, Ziyue Xu, Philip Caligiuri, Daniel J. Mollura, Robert H. Gilman,
The presence of a cavitary lesion is a radiographic hallmark of pulmonary tuberculosis (TB). The sizes of the cavitary lesion and its proximity to the bronchial tree have been associated with mycobacterial burden (1).
Tópico(s): Lung Cancer Diagnosis and Treatment
2017 - AME Publishing Company | Journal of Thoracic Disease
Arie G. Trouw, Ashish Patel, Andrew Yang, Julio J. Jauregui, Daniel A. Caligiuri, Jack Choueka,
Carpal tunnel syndrome (CTS) has multiple implications on patient quality of life. In particular, CTS may affect quality of sleep, causing sleep deprivation in extreme cases. Carpal tunnel release (CTR) surgery may aid in resolving these disturbances. The purpose of our study was to investigate whether patients who have undergone CTR have improved sleep quality and to determine the timeline for such improvement. Twenty-one patients were prospectively enrolled and followed-up for two years. They were ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2018 - Begell House | Journal of Long-Term Effects of Medical Implants
Emanuel Tupin, Bruno Poirier, M. Bureau, Jamila Khallou‐Laschet, Roger Vranckx, Giuseppina Caligiuri, A-T Gaston, J-P Duong Van Huyen, Daniel Scherman, J Bariéty, Michel Jb, Antonino Nicoletti,
Gene electrotranfer is an attractive physical method to deliver genes to target tissues. The aim of this study was to evaluate in vivo gene electrotransfer into spleen, one of the most important lymphoid organ, in order to create a new tool to modulate the immuno-inflammatory system. C57Bl/6 mice were submitted either to intramuscular electrotransfer (IME) as a reference method or to intrasplenic (ISE) gene electrotransfer. In the naked injected plasmids, the CMV promoter controlled the expression ...
Tópico(s): Microfluidic and Bio-sensing Technologies
2003 - Springer Nature | Gene Therapy
Garcia-Lazaro Rocio Soledad, Humberto Lamdán, Lorena G. Caligiuri, N. Di Lorenzo, Andrea L. Berengeno, Hugo H. Ortega, Daniel F. Alonso, Hernán G. Fariña,
Abstract Yerba Mate ( Ilex paraguariensis St. Hill. Aquifoliaceae ) is a native South American tree and has a large amount of bioactive compounds. Colorectal cancer (CRC) is one of the so‐called westernized diseases and is the third most common cancer in both men and women. Efficient strategies for the treatment of CRC are extensively being explored including dietary intervention. The objective of our research was to evaluate the effects of Yerba Mate extract on cell proliferation, invasive capacity ...
Tópico(s): Radioactivity and Radon Measurements
2020 - Wiley | Journal of Food Science
David M. Klein, Daniel A. Caligiuri, Barry M. Katzman,
This case describes the successful treatment of a child with a vascular injury and two ipsilateral grade IIIB open lower leg fractures using two local-advancement soft-tissue techniques. Multiple relaxing skin incisions were used for closure of the wound associated with the patient's midshaft tibial fracture, whereas a randomly patterned rotational fasciocutaneous flap was used for coverage of the wound associated with the patient's medial malleolar fracture. These straightforward local-advancement ...
Tópico(s): Bone fractures and treatments
1996 - Lippincott Williams & Wilkins | Journal of Orthopaedic Trauma
Michael A. Caligiuri, Christine Murray, Dedra Buchwald, Herbert Levine, Paul R. Cheney, Daniel L. Peterson, Anthony L. Komaroff, Jerome Ritz,
Natural killer (NK)3 cells are large granular lymphocytes that appear to play a significant role in the host's defense against viral infection. We performed an extensive phenotypic and functional characterization of NK cells on 41 patients with the chronic fatigue syndrome (CFS), or "chronic active Epstein-Barr virus infection" syndrome, and on 23 age- and sex-matched asymptomatic control subjects in an attempt to further characterize this illness. These studies demonstrated that a majority of patients ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
1987 - American Association of Immunologists | The Journal of Immunology
Cynthia Fox, Chris Morrison, Lorraine O. Ramig, Shimon Sapir,
... articulatory movements (Ackermann, Hertrich, Daum, Scharf, & Spieder, 1997; Caligiuri, 1989; Connor, Abbs, Cole, & Gracco, 1989; Forrest, Weismer, Turner, 1989; Leanderson, Meyerson, & Persson, 1971; Netsell, Daniel, & Celesia, 1975). Recent data using the spatiotemporal index ( ...
Tópico(s): Phonetics and Phonology Research
2002 - American Speech–Language–Hearing Association | American Journal of Speech-Language Pathology
Nina Kerres, Steffen Steurer, Stefanie Schlager, Gerd Bader, Helmut Berger, Maureen Caligiuri, Christian Dank, John R. Engen, Peter Ettmayer, Bernhard Fischerauer, Gerlinde Flotzinger, Daniel Gerlach, Thomas Gerstberger, Teresa Gmaschitz, Peter Greb, Bingsong Han, Elizabeth Heyes, Roxana E. Iacob, Dirk Kessler, Heike Kölle, Lyne Lamarre, David R. Lancia, Simon Lucas, Moriz Mayer, Katharina Mayr, Nikolai Mischerikow, Katja Mück, Christoph Peinsipp, Oliver Petermann, Ulrich Reiser, Dorothea Rudolph, Klaus Rumpel, Carina Salomon, Dirk Scharn, Renate Schnitzer, Andreas Schrenk, Norbert Schweifer, Diane Thompson, Elisabeth Traxler, Roland Varecka, Tilman Voss, A. Weiss-Puxbaum, Sandra Winkler, Xiaozhang Zheng, Andreas Zoephel, Norbert Kraut, Darryl B. McConnell, Mark Pearson, Manfred Koegl,
The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Disruption of its interaction with transcriptional repressors interferes with the oncogenic effects of BCL6. We used a structure-based drug design to develop highly potent compounds that block this interaction. A subset of these inhibitors also causes rapid ubiquitylation and degradation of BCL6 in cells. These compounds display significantly stronger induction ...
Tópico(s): CAR-T cell therapy research
2017 - Cell Press | Cell Reports
William S. Dalton, Daniel M. Sullivan, Jeffrey Ecsedy, Michael A. Caligiuri,
Technological advances have led to the identification of biomarkers and development of novel target‐based therapies. While some novel therapies have improved patient outcomes, the prevalence and diversity of biomarkers and targets in patient populations, especially patients with cancer, has created a challenge for the design and performance of clinical trials. To address this challenge we propose that prospective cohort surveillance of patients may be a solution to promote clinical trial matching ...
Tópico(s): Genetic factors in colorectal cancer
2018 - Wiley | Clinical Pharmacology & Therapeutics
Alexander B. Niculescu, Len L. Lulow, Corey A. Ogden, H Le-Niculescu, Daniel R. Salomon, Nicholas J. Schork, Michael P. Caligiuri, James B. Lohr,
Abstract Psychiatric phenotypes as currently defined are primarily the result of clinical consensus criteria rather than empirical research. We propose, and present initial proof of principle for, a novel approach to characterizing psychiatric phenotypes. We have termed our approach PhenoChipping, by analogy with, and borrowing paradigms and tools from, gene expression microarray studies (GeneChipping). A massive parallel profiling of cognitive and affective state is done with a PhenoChip composed ...
Tópico(s): Bioinformatics and Genomic Networks
2006 - Wiley | American Journal of Medical Genetics Part B Neuropsychiatric Genetics
Daniel D. Sewell, Angela B. Kodsi, Michael P. Caligiuri, Dilip V. Jeste,
Metoclopramide (MCP) is a D-2 receptor blocker (Kebabian and Calne 1979), which has been available by prescription in the United States since 1979 for use as an antiemetic in a wide range of situations. One of the common indications for MCP is the e Woerner et al1993). There have been case reports but few systematic studies of MCP-associated TD (Sewell et al 1992; Sewell and Jeste 1992; Ganzini et a1 1993). We present hkre preliminary results of a clinical study of MCPassociated TD. We wished to study ...
Tópico(s): Schizophrenia research and treatment
1994 - Elsevier BV | Biological Psychiatry
Barry M. Katzman, Daniel A. Caligiuri, David M. Klein,
A different variant of a profundus tendon avulsion is described, in which the avulsed tendon injury (Leddy and Packer Type I, II, or III) is associated with an extraarticular fracture of the distal phalanx.
Tópico(s): Tendon Structure and Treatment
1997 - SAGE Publishing | Journal of Hand Surgery (European Volume)
Daniel D. Sewell, Blain H. Yoshinobu, Michael P. Caligiuri, Dilip V. Jeste,
Metoclopramide, a drug used almost exclusively for medical indications, is a dopamine (D-2) receptor blocker and has been reported to cause extrapyramidal side effects. We present two case reports of hemodialysis patients who were treated with metoclopramide for diabetic gastroparesis. Within 12 months of beginning treatment, both patients developed persistent tardive dyskinesia. These cases highlight the fact that some patients who benefit from metoclopramide may also have a relatively high risk ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
1992 - Elsevier BV | General Hospital Psychiatry
Alice S. Mims, Anjali Mishra, Shelley Orwick, James S. Blachly, Rebecca B. Klisovic, Ramiro Garzon, Alison R. Walker, Steven M. Devine, Katherine Walsh, Sumithira Vasu, Susan P. Whitman, Guido Marcucci, Daniel M. Jones, Nyla A. Heerema, Gerard Lozanski, Michael A. Caligiuri, Clara D. Bloomfield, John C. Byrd, Richard Piekarz, Michael R. Grever, William Blum,
KMT2A partial tandem duplication occurs in approximately 5–10% of patients with acute myeloid leukemia and is associated with adverse prognosis. KMT2A wild type is epigenetically silenced in KMT2A partial tandem duplication; re-expression can be induced with DNA methyltransferase and/or histone deacetylase inhibitors in vitro, sensitizing myeloid blasts to chemotherapy. We hypothesized that epigenetic silencing of KMT2A wildtype contributes to KMT2A partial tandem duplication-associated leukemogenesis ...
Tópico(s): Histone Deacetylase Inhibitors Research
2018 - Ferrata Storti Foundation | Haematologica
Produção Nacional
Revisado por pares
Lorena G. Caligiuri, Adolfo E. Sandoval, José Carlos Miranda, Felipe Arley Costa Pessoa, María Soledad Santini, Oscar Daniel Salomón, Nágila Francinete Costa Secundino, Christina B. McCarthy,
Numerous protocols have been published for extracting DNA from phlebotomines. Nevertheless, their small size is generally an issue in terms of yield, efficiency, and purity, for large-scale individual sand fly DNA extractions when using traditional methods. Even though this can be circumvented with commercial kits, these are generally cost-prohibitive for developing countries. We encountered these limitations when analyzing field-collected Lutzomyia spp. by polymerase chain reaction (PCR) and, for ...
Tópico(s): Trypanosoma species research and implications
2019 - Multidisciplinary Digital Publishing Institute | Methods and Protocols
Sunil M. Kurian, H Le-Niculescu, Sagar D. Patel, D. S. Bertram, Jason Davis, Charles C. Dike, N Yehyawi, Paul H. Lysaker, J Dustin, Michael P. Caligiuri, James B. Lohr, Debomoy K. Lahiri, John I. Nürnberger, Stephen V. Faraone, Mark A. Geyer, Ming T. Tsuang, Nicholas J. Schork, Daniel R. Salomon, Alexander B. Niculescu,
There are to date no objective clinical laboratory blood tests for psychotic disease states. We provide proof of principle for a convergent functional genomics (CFG) approach to help identify and prioritize blood biomarkers for two key psychotic symptoms, one sensory (hallucinations) and one cognitive (delusions). We used gene expression profiling in whole blood samples from patients with schizophrenia and related disorders, with phenotypic information collected at the time of blood draw, then cross- ...
Tópico(s): Tryptophan and brain disorders
2009 - Springer Nature | Molecular Psychiatry
Michael A. Caligiuri, Christine Murray, Robert J. Soiffer, Thomas R. Klumpp, Michael V. Seiden, K Cochran, Christine Cameron, C Ish, Lynn J. Buchanan, Daniel A. Garcı́a,
In previous clinical trials, recombinant interleukin-2 (rIL-2) has been infused at high doses over short periods of time to generate lymphokine-activated killer (LAK) cells in vivo. These trials have been limited by severe toxicities, and the immunologic effects of rIL-2 have been transient. The present study was designed to assess the toxicity and immunologic effects of prolonged administration of low doses of rIL-2. In this phase I study, patients with advanced cancer were scheduled to receive intravenous ( ...
Tópico(s): Hematopoietic Stem Cell Transplantation
1991 - Lippincott Williams & Wilkins | Journal of Clinical Oncology