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Jornais Acesso aberto

Jonathan Northcroft, Tracey Boles, John Dugdale, Hala Jaber, William Kay, John Sillers, Matthew Wall, Barbara Hall, Bill Gleave Chairman, Jim Munro, Jon Swain, Dominic Sandbrook, Günter Grass, Sally Brock, Helen Davies, Nicholas Rufford, Rob Hughes, Ian Wylie, Mariusz Lodkowski, Peter Whittle, F Parker, E Young, John Waples Business Editor, L Todd, Liz Hancock, Frank Whitford, Jenny Dalton, Ivo Tennant, Dr Raphael Ehan, Paul Hornby, Justine Roberts, David Smith, Mike Birarritz, Duncan Bannatyne, Neil Wormald, Peter Cosco, Mark Hughes, Andrew Sullivan, E P, Brian Saffer, Clive Davis, Trevor Allanson, K R, Adam Abdelnoor Cheif Executive, Nick Leslie, C D, Steve Barnes, Martin Jol, Paul Jewell, Tony Allen-Mills, Simon Wilde, William Hague, D C, Martin James, Ariel Leve, Andrew Franked, Robert Winnett, Andrew Clover, Sir Alex Ferguson, Irwin Stelzer, Peter Wilson, Rosie Millard, David Dougill, Arsene Wenger, D R, Peter Barron Editor, Christopher Hart, Colin Taylor, Wayne Rooney, Nick Savage, Geraldine Hackett, Paul Flynn, H C, Rob Maul, Alistair Weaver, Lynda Hopkins, Paul Forsyth, Hugh Canning, Isabel Oakeshott, Glenn Roeder, Jeremy Clarkson, David Cairns, John Topley, Edward Porter, Elizabeth Shepherd, Claire Newell, Michael Portillo, Julian Grenfell, Renny Snell, Giles Chapman, S L, Patricia Nicol, Sarah Dempster, Adrian Turpin, Brian Cox, Dave Pollard, Peter Logan, Kathy Shuttleworth, Anita Chaudhuri, Richard Fletcher, Sylvia Downing, Dominic Connell, Rafael Benitez, Jeremy Taylor, Jeff Potter, Sarah-Kate Templeton Health Correspondent, Paul Bailey, Jason Dack, Jenni Murray, Max Hastings, Michael Waugh, Paul Ham, Stuart Wavell, Christopher Silvester, Harry Redknapp, John Stobie, Angela Newing, Leo Sayer, Paul Kimmage, Giles Hattersley, Chris Woodhead, Monsieur Mangetout, Roy Richardson, Phill Spencer, Paul Driver, Derek Clements, Miami Vice, John Follain, Richard Brooks, Hyman Mintz, Arthur Lee, Ian Hawkey, Lord March, Stuart Andrews, Caroline Scott, David Leppard, Shelley Von Strunckel, Surinder Bassi, Mark Edwards, Heston Blumenthal, Trevor Hamley, Chris Coleman, Stephen Clarke, Ken Scants, Christina Lamb, Neil Warnock, Ross Lee, Raymond Keene, C L, Cliff Wilton, Rod Liddle, Lawrence Booth, Penelope Lively, Robbie Hudson, Ifor R Griffiths, Kipper Williams, David Moyes, Emma Smith, Stephen Jones, Dominic O'Connell, Stephen Bleach, Louise Armitstead, Uzi Mahnaimi, Mary Lobo, Nick Cain, Steve Coppell, Alan Pardew, Michael Wright, Jose Mourinho, James Dyson, Susan Kelly, Simon Burton, Caroline Donald, D Hall, Simon Baylik, Philip Sen, S A, Stuart Pearce, Rowan Williams, Trevor Lewis, Gareth Southgate, Caroline Branningan, David Gunn, S P, Colin McDowell, Stephen Armstrong, Adrian Boothroyd, John Elliott, Anna Mikhailova, Isabel Oakeshott Deputy Political Editor, Russell Miller, Bethan Cole, Antony Sattin, Lauren Howey, Roland White, N R, Steven Swinford, Alison Jane Reid, J Higgins, Abul Taher, J M Pinney, Rachel Johnson, Maurice Chittenden, Vincent Marcello, Mark Watts, Alastair McKay, Virginia Rounding, Mark Franchetti, Jon Ungoed-Thomas, Mike Brewer, Andrew Rogers, John Penman, M E, Sam Allardyce, Clare Francis, Michael Smith, John Harlow, Patrick Grant, Martin O'Neill, Fiona Bruce, Chris Haslam, Dipesh Gadher, Tom Baird, Mark Kleinman, Sarah Anderson, John Waples, Navid Akhtar, Mary Davies, Harry Arnold, A A Gill, David Parsons, Hunter Davies, Matthew Campbell, Brian Glanville, Daniel Foggo, Tom Steer, Martin Wroe, Dainel Emery, Soph Gill, W Pope, Margo Stilley, Simon Jenkins, Stephen Pettitt, Andrew Lycett, Claudia Croft, Jessica Bown, Olivia Cole, T L, Ciaran Hancock, R H, Sally Kinnes, Hollie Smith, Chris Morris, Roger Cooper, Clarence Barrett, Roger Dobson, Peter Almond, Kevin Baker Warrant Officer, Brian Doogan, John Aizlewood, Minette Marrin, Iain Dowie, J P, James Scoltock, Gordon Christian, Ken Lunn, Joe Lovejoy, Graham Norwood, Andrew Frankel, P W, David Budworth, Hugh Pearman, E U, Andrew Davidson, Dan Cairns, David Grylls, Katy Duke, Tony Balding, David Smith Economics Editor, Tom Deveson, R U, Sarah Baxter, Joanna Simon, Matthew Goodman, India Knight, Kate Spicer, Jason Dawe, Richard Lewis, Sian Griffiths, Helen Stewart,

... Annick Massis, Bruno de Simone, Orquesta Sinfonica de Galicia, cond Riccardo Frizza Decca 475 7688 Beethoven Violin Sonatas, Op 23, Op 30 No 2 Andreas Staier, Daniel Sepec Harmonia Mundi HMC 901919 Sibelius String Quartets, ...

2006 - Gale Group | Sunday Times HA GDA

Artigo Revisado por pares

Reginald L. Tennyson, Guillermo S. Cortez, Héctor J. Galicia, Charles R. Kreiman, Christina M. Thompson, Daniel Romo,

β-Lactones are useful synthetic intermediates allowing access to a number of functional arrays. In this report, enantiomerically pure 4-trichloromethyl-2-oxetanone is shown to be a versatile amino acid synthon leading to a variety of γ-substituted α-amino acid precursors. The utility of this methodology was demonstrated by the concise synthesis of a protected homoserine equivalent, α-azidobutyro lactone, and a naturally occurring α-amino acid from the seeds of Blighia unijugata.

Tópico(s): Carbohydrate Chemistry and Synthesis

2002 - American Chemical Society | Organic Letters

Jornais Acesso aberto

Phil Yates, Arthur Wheeler, Cath Urquhart, Sally Staples, Mike Gerrard, Helen Johnstone, Alasdair Riley, Robert Cole, Portia Colwell, Jim Moran, nigella lawson, Andrew Pierce, Sally Brock, Adrian Lee, Grace Bradberry, Barbara Segall, S. A. M. Quadri, Jane MacQuitty, Richard Ford, Home Correspondent, John Morgan, Christopher Somerville, Paul Hoggart, jonathan meades, Mark Souster, David Rhys Jones, Karen Woolfson, John O'Leary, Education Editor, Gavin Lumsden, Raymond Snoddy, Media Editor, Tom Baldwin, Andrew Pierce and Helen Rumbelow, Philip Howard, ray main, James R. Vandeleur, Dina Shiloh, Ian Murray, D. J. Tyler, Matthew Taylor, Caroline Merrell, Banking Correspondent, Angela Court, mark harrison, Clive Davis, Alasdair Couper-Johnston, Kate Reardon, Tamsin Berryford, Anne Robinson, Michael Evans, Defence Editor, Peter McBeath, Tony Patrick, Kevin Eason, john diamond, Fraser Nelson, Retail Correspondent, Raymond Snoddy, Clare Stewart, Dr David G. Green, Director, Antonia Senior, Carl Evans, David McVay, Andrew Eccles, Stephen McClarence, Valerie Elliott, D. R., John Davis, Simon Stow, Dominic Walsh, Ruth Gledhill, John Knight, Jerome Boyd Maunsell, Debra Craine, Mike Pattenden, Angela's Ashes, Rob Penn, Stephen Anderton's, Peter Mandelson, Richard Robinson, Ruth Gledhill Religion Correspondent, Martin Barrow, EJ, Candida Crewe, Jo Morris, Robin Young, Oliver Wright, Ian Murray, Medical Correspondent, Mark Inglefield, Roger Harrison (Director), Nicholas Roe, Peter Millar, T. P., John O'Leary, seamus murphy, Doug Sager, Frances Bissell, Alix Ramsay, Tennis Correspondent, David Hands, P. B., Charles Bremner, Lisa Armstrong Fashion Editor, Shahin Hussain, Anthea Lawson, Martin Palmer, Peter Barnard, jasper rees, Derwent May, VW, Russell Kempson, Paula Hawkins, Maria Harding, Chloe Bryan-Brown and Juliet Sutcliffe, Christina Speight, Nigel Williamson, Ed Potton, Richard Colwill, Stephen Anderton, Paul Durman, Amber Cowan, Elizabeth Knox, Giles Tremlett and Michael Harvey, Frank Leboeuf, Martyn Palmer, Christopher Martin-Jenkins, Adam Sherwin, Gary Jacob and Emily Davies, Gabriella Gamini, David Miller, Murray Boldt, L. G., alan jackson, Simon de Bruxelles, CJP, Rob Wright, Eduard Zuiderwijk, MH, Christina Koning, Sarah Turner, Adam Jones, Rachael Jolley, Raymond Keene, Vaughan Freeman, Adam Sage, C. R. Hart (Assistant Chief Executive), David Robinson, Clive Mathieson, Matthew Pryor, John Russell Taylor, Matt Dickinson, sanjiv bhattacharya, Tom Baldwin, Deputy Political Editor, mike owen, Lucy Pinney, Anne Boston, Alix Ramsay, James Allcock, Roland Brown, JRT, Jeannette Hyde, Nigel Hawkes, Clive Petty, Caroline Merrell, Ben Beasley-Murray, Melissa Kite, Cathy Harris, Michael Arditti, Oliver Holt, Richard Owen, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, David Kettle, sarah sims, Marcel Berlins, Roger Boyes, Michael A. Weller, Brian Ely, Nick Hasell, Stewart Tendler, Stephanie Billen, Simon Grosset, Alison Kervin, Rugby Editor, Alfred Van Veen, Roland White, Henry Harris's, BN, Richard Langdon, RL, Philip Webster Political Editor, Giles Whittell, perou, Christopher Walker, James Pringle, Valerie Elliott, Countryside Editor, Machiavelli, Sophie Ratcliffe, Alex O'Connell, Mel Webb, Srikumar Sen Boxing Correspondent, William Oddie, Deborah King, AL, Matthew Parris, Warren Edwardes, David Watson, Melissa Kite Political Reporter, Tim Wapshott, Russell Jenkins, AS, Alan Lee, Jane Owen, Ben MacIntyre, A. M. Troth, John Wilson, vinny lee, C. J. Cheetham, Josa Young, alison jane reid, Michael Dynes, Richard Miles, Graham Searjeant, Fraser Nelson, Anne Ashworth Personal Finance Editor, Annabelle Thorpe, Jason Allardyce and Shirley English, Mark Henderson, Martin Waller, Chris Ayres, Margery Mallinder, Peter Ingham, Danny Baker, Fran Littlewood, N G McMullen, Laura Peek, Kathleen Wyatt, Benedict Nightingale, Alexandra Frean, Social Affairs Correspondent, Keith Bill, Dr Thomas Stuttaford, Jill Crawshaw, Peter D. Rossdale, David Powell, Alyson Rudd, Tom Chesshyre, Alasdair Murray and Susan Emmett, Fred Dellar, Paul Connolly, Valerie Grove, Thomas Cussans, Elizabeth Buchan, SJ, Michael Evans, M. E. D. Biggs, Darcus Howe, Penny Perrick, Sally Patten, Cath Urquhart Travel Editor, Ellie Broadbridge, Andy Enright, Paul Richardson, Edward Gorman Sailing Correspondent, Martin Fletcher and Tom Baldwin, G. Mills, Michael Theodoulou and Daniel McGrory, Allan Rutherford, Gill Hornby, john angerson, Christopher Irvine, Eric Hale, Susan Emmett,

... jackson calls darcus howe From giles tremlett in galicia .. . Women are proving just as deadly as men ...

2000 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Genevieve M. Vidanes, Frédéric D. Sweeney, Sarah Galicia, Stephanie Cheung, John P. Doyle, Daniel Durocher, David P. Toczyski,

The Saccharomyces cerevisiae polo-like kinase Cdc5 promotes adaptation to the DNA damage checkpoint, in addition to its numerous roles in mitotic progression. The process of adaptation occurs when cells are presented with persistent or irreparable DNA damage and escape the cell-cycle arrest imposed by the DNA damage checkpoint. However, the precise mechanism of adaptation remains unknown. We report here that CDC5 is dose-dependent for adaptation and that its overexpression promotes faster adaptation, ...

Tópico(s): Cancer-related Molecular Pathways

2010 - Public Library of Science | PLoS Biology

Artigo Acesso aberto Revisado por pares

Pamela Kanellis, Mark Gagliardi, Judit P. Banáth, Rachel K. Szilard, Shinichiro Nakada, Sarah Galicia, Frédéric D. Sweeney, Diane C. Cabelof, Peggy L. Olive, Daniel Durocher,

Genome instability is a hallmark of cancer cells. One class of genome aberrations prevalent in tumor cells is termed gross chromosomal rearrangements (GCRs). GCRs comprise chromosome translocations, amplifications, inversions, deletion of whole chromosome arms, and interstitial deletions. Here, we report the results of a genome-wide screen in Saccharomyces cerevisiae aimed at identifying novel suppressors of GCR formation. The most potent novel GCR suppressor identified is BUD16, the gene coding ...

Tópico(s): Metabolism and Genetic Disorders

2007 - Public Library of Science | PLoS Genetics

Artigo Acesso aberto Revisado por pares

Giänreto Manatschal, Daniel Bernoulli,

A comparison of the reconstructed southeastern margin of the Tethys ocean with the present‐day Galicia margin shows that although both margins are of different age and had a different fate, their architectures and tectonic evolutions are very similar. Along both non‐volcanic margins the site of rifting shifted from a broad area in the future proximal margins to a localized area in its distal parts, accompanied by a change in the mode of extension. During the initial phase of rifting, extension was ...

Tópico(s): earthquake and tectonic studies

1999 - Wiley | Tectonics

Artigo Acesso aberto Revisado por pares

Christine Koch, Roger Agyei, Sarah Galicia, Pavel Metalnikov, Ed O’Donnell, Andrei Starostine, Michael Weinfeld, Daniel Durocher,

Article23 September 2004free access Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV Christine Anne Koch Corresponding Author Christine Anne Koch Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada Radiation Medicine Program, Princess Margaret Hospital (UHN), Toronto, ON, Canada Department of Radiation Oncology, University of Toronto, Toronto, Canada Search for more papers by this author Roger Agyei Roger Agyei Samuel Lunenfeld ...

Tópico(s): PARP inhibition in cancer therapy

2004 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Nina Bernstein, R. Scott Williams, M.L. Rakovszky, Diana Cui, Ruth Green, Feridoun Karimi‐Busheri, Rajam S. Mani, Sarah Galicia, Christine Koch, Carol E. Cass, Daniel Durocher, Michael Weinfeld, J. N. Mark Glover,

Mammalian polynucleotide kinase (PNK) is a key component of both the base excision repair (BER) and nonhomologous end-joining (NHEJ) DNA repair pathways. PNK acts as a 5'-kinase/3'-phosphatase to create 5'-phosphate/3'-hydroxyl termini, which are a necessary prerequisite for ligation during repair. PNK is recruited to repair complexes through interactions between its N-terminal FHA domain and phosphorylated components of either pathway. Here, we describe the crystal structure of intact mammalian PNK ...

Tópico(s): Cancer-related Molecular Pathways

2005 - Elsevier BV | Molecular Cell

Artigo Acesso aberto Revisado por pares

Edgar Galicia–Andrés, Dražen Petrov, Martin H. Gerzabek, Chris Oostenbrink, Daniel Tunega,

Computational models of clay minerals and their interactions with the surrounding medium are highly valuable to study adsorption processes at an atomistic resolution, which may be relevant in different areas such as chromatography, environmental chemistry, and so forth. In this work, we analyzed the effect of the treatment of long-range interactions on the polarization of kaolinite–water interfacial systems in terms of structural, electric and dynamic properties, and hydrogen bonds. When using conventional ...

Tópico(s): Geophysical and Geoelectrical Methods

2019 - American Chemical Society | Langmuir

Artigo Revisado por pares

Rafael J. Salín-Pascual, Daniel Granados‐Fuentes, Lourdes Galicia-Polo, Estela Nieves, J. Christian Gillin,

Abstract The muscarinic antagonist biperiden produces a dose-dependent inhibition of (REM) sleep on acute administration. The present study addressed the possibility of pharmacological tolerance after repeated biperiden administration. Six healthy volunteers were studied under sleep laboratory conditions in the following situations: one acclimatization night, two baseline (that were averaged), 4 nights of biperiden administration, and 4 nights of placebo recovery administration. Six milligrams of biperiden ...

Tópico(s): Neuroscience and Neuropharmacology Research

1993 - Elsevier BV | Biological Psychiatry

Artigo Revisado por pares

Sergio Cinza‐Sanjurjo, Daniel Rey‐Aldana, Enrique Gestal-Pereira, C Calvo-Gomez,

Conocer cuál es el grado de control de los pacientes anticoagulados en seguimiento por atención primaria en Galicia y si la determinación por número de controles es comparable al Rosendaal para estimar el tiempo en rango terapéutico. Estudio transversal que incluyó a pacientes > 65 años, diagnosticados de fibrilación auricular no valvular, anticoagulados durante al menos 1 año. Se consideró buen control cuando el tiempo en rango terapéutico era > 65% calculado por Rosendaal o 60% estimado por el número ...

Tópico(s): Cardiac Arrhythmias and Treatments

2014 - Elsevier BV | Revista Española de Cardiología

Artigo Acesso aberto Revisado por pares

Daniel Vázquez‐Sánchez, Marta López Cabo, Paula Saá-Ibusquiza, Juan José Rodríguez-Herrera,

A total of 298 fishery products purchased from retail outlets in Galicia (NW Spain) between January 2008 and May 2009 were analyzed for the presence of Staphylococcus aureus. S. aureus was detected in a significant proportion of products (~ 25%). Incidence was highest in fresh (43%) and frozen products (30%), but it was high in all other categories: salted fish (27%), smoked fish (26%), ready-to-cook products (25%), non-frozen surimis (20%), fish roes (17%) and other ready-to-eat products (10%). A significant ...

Tópico(s): Identification and Quantification in Food

2012 - Elsevier BV | International Journal of Food Microbiology

Artigo Acesso aberto Revisado por pares

J. Randall, C. E. Bradley, Floris V. Van Der Gronden, Asier Galicia, M. H. Abobeih, Matthew Markham, Daniel J. Twitchen, Francisco Machado, Norman Y. Yao, T. H. Taminiau,

The discrete time crystal (DTC) is a recently discovered phase of matter that spontaneously breaks time-translation symmetry. Disorder-induced many-body-localization is required to stabilize a DTC to arbitrary times, yet an experimental investigation of this localized regime has proven elusive. Here, we observe the hallmark signatures of a many-body-localized DTC using a novel quantum simulation platform based on individually controllable $^{13}$C nuclear spins in diamond. We demonstrate the characteristic ...

Tópico(s): Topological Materials and Phenomena

2021 - American Association for the Advancement of Science | Science

Artigo Acesso aberto Revisado por pares

Diego Rodríguez-Toubes Muñiz, Stefan Gößling, C. Michael Hall, Daniel Scott,

Flooding, as a result of heavy rains and/or storm surges, is a persistent problem in coastal areas. Under scenarios of climate change, there are expectations that flooding events will become more frequent in some areas and potentially more intense. This poses a potential threat to coastal communities relying heavily on coastal resources, such as beaches for tourism. This paper develops a methodology for the assessment of coastal flooding risks, based on an index that compares 16 hydrogeomorphological, ...

Tópico(s): Tropical and Extratropical Cyclones Research

2017 - Multidisciplinary Digital Publishing Institute | Environments

Artigo Revisado por pares

Manoel Lago-Vila, Daniel Arenas-Lago, María Luisa Andrade Couce, F.A. Vega,

This study was carried out on minesoils from a copper mine in Touro, NW Spain. The aims were to evaluate the effectiveness of a variety of extractants for predicting the availability of trace metals, to use the plants that colonize the affected area to evaluate metal absorption, and to assess the potential of colonist vegetation for the phytoremediation of mine tailings. Copper, Mn, Ni and Zn were found in all soils. Total soil Cu exceeds the intervention limits. In general, the extracted amount ...

Tópico(s): Coal and Its By-products

2014 - Elsevier BV | Journal of Geochemical Exploration

Artigo Revisado por pares

Ricardo David Valdez‐Cepeda, Daniel Hernández-Ramírez, B. Mendoza, J. F. Valdés‐Galicia, Dolores Maravilla,

Interest in climate change has increased over the last 30 years due largely to global predictions associated with the greenhouse effect, which appear to lead to a substantial increase in planetary temperature. Implications of such results have led many scientists to examine climatic records from different regions of the world in order to understand temperature behavior. However, many researchers have noted that changes in temperature variability are also important in determining the future temperature ...

Tópico(s): Climate variability and models

2003 - World Scientific | Fractals

Artigo

Sergio Cinza‐Sanjurjo, Daniel Rey‐Aldana, Enrique Gestal-Pereira, C Calvo-Gomez,

To determine the degree of control of patients on anticoagulants in follow-up in primary care in Galicia and investigate whether time in therapeutic range as estimated using the number of acceptable controls is comparable with the estimation using the Rosendaal method. Transversal study that included patients older than 65 years, diagnosed with nonvalvular atrial fibrillation, on anticoagulants for at least 1 year. Control was considered good when the time in therapeutic range was greater than 65%, ...

Tópico(s): Venous Thromboembolism Diagnosis and Management

2014 - Elsevier BV | Revista Española de Cardiología (English Edition)

Artigo Revisado por pares

Zeltzin Alejandra Ceja-Galicia, Diana Calderón-DuPont, Alberto Daniel, Luz María Chiu, Andrea Díaz‐Villaseñor,

Arsenic is a risk factor for type 2 diabetes and cardiovascular disease. However, little is known about arsenic effects over adipocyte endocrine functionality, particularly for leptin and adiponectin, and about its interaction with dietary components, which are the main environmental regulators of adipose tissue functionality. The aim of this work was to evaluate leptin and adiponectin in mature 3T3-L1 adipocytes exposed to palmitate (simulating excess fat intake), arsenite, or both throughout two ...

Tópico(s): Retinoids in leukemia and cellular processes

2021 - Elsevier BV | Life Sciences

Artigo Acesso aberto Revisado por pares

Serge Gofas, Ángel A. Luque, Joan Daniel Oliver, José Templado, Alberto Serrano,

An illustrated checklist of the Mollusca of Galicia Bank, a large and deep seamount off the NW Iberian Peninsula, is provided. The studied material was collected in 8 samples of Seamount 1 cruise (1987), 7 samples of ECOMARG 0709 (2009) and 36 samples of BANGAL 0711 (2011), between 615 and 1768 m. A total of 212 species are known to occur at the Galicia Bank (1 Monoplacophora, 7 Solenogastres, 3 Polyplacophora, 132 Gastropoda, 54 Bivalvia, 6 Scaphopoda, and 9 Cephalopoda), 21 of which from previous ...

Tópico(s): Marine Bivalve and Aquaculture Studies

2021 - Consortium of European Natural History Museums | European Journal of Taxonomy

Artigo Acesso aberto Revisado por pares

Rafael J. Salín-Pascual, Daniel Grandos-Fuentes, Lourdes Galicia-Polo, Estela Nieves, Timothy Roehrs, Thomas Roth,

Sixteen subjects were assigned to a group using either placebo or biperiden, with eight subjects in each group. Both groups were studied for one acclimatization night, one baseline night, four nights of rapid eye movement (REM) sleep deprivation and two recovery nights. All the subjects received either placebo or 4 mg biperiden 1 hour before sleep during the four nights of REM sleep deprivation. During the baseline and the recovery nights both groups received placebo capsules.

Tópico(s): Circadian rhythm and melatonin

1992 - Oxford University Press | SLEEP

Artigo Revisado por pares

G. Boillot, S. Grimaud, A. Mauffret, D. Mougenot, Jacques Kornprobst, Juliette Mergoil-Daniel, G. Torrent,

A serpentinite diapir made of altered plagioclase-bearing lherzolites, has been emplaced west of the Galicia Bank at the boundary between oceanic crust and the probable thinned continental crust, that underlies the Iberian margin.

Tópico(s): Paleontology and Stratigraphy of Fossils

1980 - Elsevier BV | Earth and Planetary Science Letters

Artigo Acesso aberto Revisado por pares

Mario Buenrostro–Jáuregui, Luis Miguel Rodríguez–Serrano, María Elena Chávez–Hernández, Alejandro Tapia-de-Jesús, Jesús Jasso Mata, Florencia Mata, Oscar Galicia-Castillo, Daniel Tirado-Martínez, Sylvia Ortega‐Martínez, Erik Bojorges-Valdez,

Brainwaves amplitude obtained from electroencephalography (EEG) has been well-recognized as a basis for cognitive capacity, memory, and learning on animals and humans. Adult neurogenesis mechanism is also linked to memory and learning improvement. Traditionally, researchers used to assess learning and memory parameters in rodent models by behavioral tasks. Therefore, the simultaneous monitoring of behavioral changes and EEG is particularly interesting in correlating data between brain activity and ...

Tópico(s): Memory and Neural Mechanisms

2020 - MyJOVE | Journal of Visualized Experiments

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luciane Cruz Lopes, Maribel Salas, Claudia Garcia Serpa Osório-de-Castro, Lisiane Freitas Leal, Svetlana V. Doubova, Martín Cañás, Anahí Dreser, Ángela Acosta, André Oliveira Baldoni, Cristiane de Cássia Bergamaschi, Daniel Marques Mota, Diana Lizbeth Gómez Galicia, Dino Sepúlveda, Edgard Narvaez Delgado, Elisângela da Costa Lima, Felipe Vera, Felipe Ferré, Gustavo H. Marín, I. Cánovas Olmos, Ivan Ricardo Zimmermann, Izabela Fulone, Juan Roldán‐Saelzer, Juan Carlos Sánchez‐Salgado, Lucila I. Castro‐Pastrana, Luiz Júpiter Carneiro de Souza, Manuel Machado Beltrán, Marcus Tolentino Silva, María Belén Mena, Marta Maria de França Fonteles, Martín Urtasun, Mónica Tarapués, Patricia Granja, Natalia Medero, Raquel Herrera Comoglio, Silvio Barberato‐Filho, Taís Freire Galvão, Vera Lúcia Luiza, Yared Santa‐Ana‐Téllez, L. Yesenia Rodríguez‐Tanta, Monique Elseviers,

Drug utilization research (DUR) contributes to inform policymaking and to strengthen health systems. The availability of data sources is the first step for conducting DUR. However, documents that systematize these data sources in Latin American (LatAm) countries are not known. We compiled the potential data sources for DUR in the LatAm region.A network of DUR experts from nine LatAm countries was assembled and experts conducted: (i) a website search of the government, academic, and private health institutions; ( ...

Tópico(s): Antibiotic Use and Resistance

2021 - Wiley | Pharmacoepidemiology and Drug Safety

Artigo Revisado por pares

Anxo Mena, Guillermo Francés, Marta Pérez‐Arlucea, Pablo Aguiar, José Daniel Barreiro‐Vázquez, A. Iglesias, Andrés Fernández Barreiro,

Abstract Non-destructive techniques of core analysis, especially of marine cores, are being broadly employed for sedimentary, paleoceanographic and paleoclimate research. In particular, Computed Tomography scanning (CT-scanning) allows acquisition of 3D and 2D images, according to desired planes, and thus the identification of sedimentary structures, large grains and their distributions as well as direct measurements of material densities. The most significant contribution of this technique is the ...

Tópico(s): Pleistocene-Era Hominins and Archaeology

2015 - Elsevier BV | Sedimentary Geology

Artigo Acesso aberto Revisado por pares

Cindy Negrete-González, Edgar Turrubiartes-Martínez, Othir G. Galicia-Cruz, Daniel E. Noyola, Gerardo Martínez‐Aguilar, Luis Fernando Pérez-González, Roberto González‐Amaro, Perla Niño-Moreno,

Abstract Background Staphylococcus aureus is a leading cause of broad-spectrum infections both in the community and within healthcare settings. Methicillin-resistant Staphylococcus aureus (MRSA) has become a global public health issue. The aim of this study was to examine the clinical and molecular characteristics of Staphylococcus aureus isolates and to define the population structure and distribution of major MRSA clones isolated in a tertiary-care hospital in Mexico. Results From April 2017 to ...

Tópico(s): Bacterial Identification and Susceptibility Testing

2020 - BioMed Central | BMC Microbiology

Artigo Revisado por pares

Laura Berrón‐Ruiz, Andrea Morin-Contreras, V Cano-García, Marco Antonio Yamazaki‐Nakashimada, Héctor Gómez-Tello, María Eugenia Vargas-Camaño, R Canseco-Raymundo, F Saracho-Weber, Dino Pietropaolo-Cienfuegos, Blanca Del Río-Navarro, Tamara Staines‐Boone, Francisco Espinosa‐Rosales, Ariadna González‐del Angel, M M Saenz-de-Ocaris, Daniel Octavio Pacheco-Rosas, Sara Elva Espinosa‐Padilla, Leopoldo Santos‐Argumedo, Lizbeth Blancas‐Galicia,

There are two inheritance patterns, the X-linked recessive (XL) pattern and the autosomal recessive pattern. There is no information on the predominant inheritance pattern of male patients with chronic granulomatous disease (CGD) in Mexico. The aim of this study was to determine the inheritance pattern in a cohort of Mexican male patients with CGD by means of the detection of an XL status carrier among their female relatives, and to describe the frequency of discoid lupus (DL) among carriers. We detected ...

Tópico(s): Calcium signaling and nucleotide metabolism

2014 - Elsevier BV | Allergologia et Immunopathologia

Artigo Acesso aberto Revisado por pares

András N. Spaan, Anna‐Lena Neehus, Emmanuel Laplantine, Frederik Staels, Masato Ogishi, Yoann Seeleuthner, Franck Rapaport, Keenan A. Lacey, Erika Van Nieuwenhove, Maya Chrabieh, David Hum, Mélanie Migaud, Araksya Izmiryan, Lazaro Lorenzo, Tatiana Kochetkov, Dani A. C. Heesterbeek, Bart W. Bardoel, Ashley Dumont, Kerry Dobbs, Solenne Chardonnet, Søren Heissel, Timour Baslan, Peng Zhang, Rui Yang, Dusan Bogunovic, Herman F. Wunderink, Pieter-Jan Haas, Henrik Molina, Griet Van Buggenhout, Stanislas Lyonnet, Luigi D. Notarangelo, Mikko Seppänen, Robert Weil, Gisela Seminario, Héctor Gomez-Tello, Carine Wouters, Mehrnaz Mesdaghi, Mohammad Shahrooei, Xavier Bossuyt, Erdal Sağ, Rezan Topaloğlu, Seza Özen, Helen L. Leavis, Maarten M. J. van Eijk, Liliana Bezrodnik, Lizbeth Blancas‐Galicia, Alain Hovnanian, Aude Nassif, Brigitte Bader‐Meunier, Bénédicte Neven, Isabelle Meyts, Rik Schrijvers, Anne Puel, Jacinta Bustamante, Ivona Aksentijevich, Daniel L. Kastner, Victor J. Torres, Stéphanie Humblet‐Baron, Adrian Liston, Laurent Abel, Bertrand Boisson, Jean‐Laurent Casanova,

The molecular basis of interindividual clinical variability upon infection with Staphylococcus aureus is unclear. We describe patients with haploinsufficiency for the linear deubiquitinase OTULIN, encoded by a gene on chromosome 5p. Patients suffer from episodes of life-threatening necrosis, typically triggered by S. aureus infection. The disorder is phenocopied in patients with the 5p- (Cri-du-Chat) chromosomal deletion syndrome. OTULIN haploinsufficiency causes an accumulation of linear ubiquitin ...

Tópico(s): Antimicrobial Resistance in Staphylococcus

2022 - American Association for the Advancement of Science | Science

Artigo Revisado por pares

Daniel Navarro, Sonia Pérez‐Castro, Matilde Trigo, Antonio Aguilera,

Presentamos el mayor estudio realizado en Galicia sobre prevalencia y distribución de genotipos/subtipos del VHC. Estudio retrospectivo recopilando al total de pacientes crónicamente infectados por VHC entre el 1 de enero del 2000 y el 31 de diciembre del 2015 en 3 de las principales áreas sanitarias: Santiago, Pontevedra y Vigo. Recogimos datos sobre prevalencia y distribución de genotipos/subtipos, vías de transmisión, género, edad y coinfección con VIH/VHB. Reclutamos a 4.469 pacientes, con una ...

Tópico(s): Liver Disease Diagnosis and Treatment

2018 - Elsevier BV | Enfermedades Infecciosas y Microbiología Clínica

Revisão Acesso aberto Revisado por pares

I. Galicia Ernst, Gabriel Torbahn, Lukas Schwingshackl, Helge Knüttel, Robert Kob, Wolfgang Kemmler, Cornel Sieber, John A. Batsis, Dennis T. Villareal, Nanette Stroebele‐Benschop, Marjolein Visser, Dorothee Volkert, Eva Kiesswetter, Daniel Schoene,

Summary Obesity and sarcopenic obesity (SO) are characterized by excess body fat with or without low muscle mass affecting bio‐psycho‐social health, functioning, and subsequently quality of life in older adults. We mapped outcomes addressed in randomized controlled trials (RCTs) on lifestyle interventions in community‐dwelling older people with (sarcopenic) obesity. Systematic searches in Medline, Embase, Cochrane Central, CINAHL, PsycInfo, Web of Science were conducted. Two reviewers independently ...

Tópico(s): Cerebral Palsy and Movement Disorders

2022 - Wiley | Obesity Reviews