
Felipe Padovani Trivelato, Eduardo Wajnberg, Marco Túlio Salles Rezende, Alexandre Cordeiro Ulhôa, Ronie Leo Piske, Thiago Giansante Abud, Luís Henrique de Castro-Afonso, Carlos Abath, Guilherme Seizem Nakiri, João Francisco Santoro Araújo, José Laércio Júnior Silva, Renato Tavares Tosello, José Ricardo Vanzin, Luciano Bambini Manzato, Carlos Eduardo Baccin, Bruno Anderson Araújo da Mota, Daniel Giansante Abud,
The safety and efficacy of the first generation of the Pipeline Embolization Device (PED; Medtronic Inc) have been proven in large case series. Ischemic events are one of the most common complications following treatment of aneurysms with flow diverters. The new PED Flex with Shield technology (PED Shield; Medtronic Inc) was introduced to minimize the rate of complications.To evaluate the outcomes of patients harboring aneurysms treated with the PED Shield.This was an observational, prospective, single- ...
Tópico(s): Moyamoya disease diagnosis and treatment
2019 - Lippincott Williams & Wilkins | Neurosurgery

Maria Carolina Guimarães, Estella G. da Mota, Daniel G. Silva, Matheus P. Freitas,
Aniline and phenol derivatives are known as aquatic pollutants, while the bacteria Vibrio fischeri and the algae Pseudokirchneriella subcapitata are widely used as ecotoxicological indicators. The toxicities of a series of aniline and phenol derivatives toward these living systems have been modelled using an augmented multivariate image analysis applied to quantitative structure–property relationship (aug-MIA-QSPR). The models for both organisms were found to be highly predictive and reliable for ...
Tópico(s): Essential Oils and Antimicrobial Activity
2014 - Elsevier BV | Chemometrics and Intelligent Laboratory Systems

Francisco R. Moreira da Mota, Daniel J. Pagano, Marina Enricone Stasiak,
An important parameter in the study of multiphase flows is the volume fraction, which is defined by the ratio between the volume occupied by a specific phase and the total volume of the mixture. This is a fundamental parameter that appears in most of the flow models and frequently is applied to assist flow pattern identification routines as well as to estimate two-phase flow rates. This paper presents a water volume fraction estimation method based on electrical capacitance tomography (ECT) called ...
Tópico(s): Geophysical and Geoelectrical Methods
2018 - IEEE Sensors Council | IEEE Sensors Journal

Noely Camila Tavares Cavalcanti Bedor, Danilo César Galindo Bedor, Carlos Eduardo Miranda de Sousa, Felipe Nunes Bonifácio, Daniel da Mota Castelo Branco, Leila Bastos Leal, Davi Pereira de Santana,
Summary A rapid method using liquid chromatography tandem mass spectrometry for the quantification of olanzapine ( OLZ ) in human plasma was developed and validated. Venlafaxine was used as the internal standard ( IS ), and the samples were extracted from 400‐ μ L human plasma with methyl tert ‐butyl ether for liquid–liquid extraction. Chromatography was performed using an ACE C18, 125 × 4.6‐mm i.d., 5‐ μ m column. The mobile phase consisted of water with 0.1% formic acid for solvent A and acetonitrile with ...
Tópico(s): Epilepsy research and treatment
2014 - Wiley | Clinical and Experimental Pharmacology and Physiology

Daniele Maria-Ferreira, Luísa Mota da Silva, Daniel Augusto Gasparin Bueno Mendes, Daniela Almeida Cabrini, Adamara Machado Nascimento, Marcello Iacomini, Thales R. Cipriani, Adair R.S. Santos, Maria Fernanda de Paula Werner, Cristiane Hatsuko Baggio,
A rhamnogalacturonan (RGal) isolated from Acmella oleracea (L.) R.K. Jansen administered by oral route showed gastroprotective activity against acute lesions induced by ethanol. In this study, we investigated the gastric ulcer healing effect of RGal and its mechanisms of action. Intraperitoneal treatment of animals with RGal protected the gastric mucosa against acute lesions induced by ethanol, with participation of gastric mucus. Furthermore, in the chronic ulcer model, oral administration of RGal ...
Tópico(s): Fungal Biology and Applications
2014 - Public Library of Science | PLoS ONE

Renata Vieira da Mota, Daniel Angelucci de Amorim, Ana Carolina Fávero, Eduardo Purgatto, Murillo de Albuquerque Regina,
Based on the concept that the trellising system affects not only sunlight interception and carbon assimilation, but also the fruitzone microclimate, which has a great impact on fruit composition and consequently on wine quality, the effect of two trellising systems - Vertical Shoot Position (VSP) and modified Geneva Double Curtain (GDC) - on wine and berry composition of Syrah grapes grown in João Pinheiro, Northeast region of Minas Gerais State, Brazil was investigated. The parameters such as pH, berry ...
Tópico(s): Postharvest Quality and Shelf Life Management
2011 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology
The ability of mouse antisera collected at different times during the course of immunization to induce homologous and heterologous (rat) PCA using a sensitization period of 2 or 72 hours was studied. The following observations were made: a. The homologous PCA activity increased during immunization whereas the heterologous PCA activity decreased; b. The 72 hour PCA titer in mice was the same as the 2 hour PCA titer in rats; c. The 72 hour PCA activity in mice and the PCA activity in rats were both ...
Tópico(s): Allergic Rhinitis and Sensitization
1969 - Elsevier BV | Life Sciences

João Gustavo Corrêa Reis, Clarissa Souza Mota Reis, Daniel César Silva da Costa, Márcia Mendonça Lucena, Armando de Oliveira Schubach, Raquel de Vasconcellos Carvalhães de Oliveira, Valéria C. Rolla, Fátima Conceição‐Silva, Cláudia Maria Valete‐Rosalino,
Introduction Laryngeal tuberculosis (LTB) is the most frequent granulomatous disease of the larynx and represents less than 2% of extrapulmonary TB cases. There are no pathognomonic clinical and endoscopic features of this disease and studies on LTB that can assist in its diagnostic characterization are lacking. Objective To identify factors associated with clinical and topographical features of LTB. Method a retrospective cross-sectional study was conducted from the medical records of 36 patients ...
Tópico(s): Mycobacterium research and diagnosis
2016 - Public Library of Science | PLoS ONE

Caio Nery, Lucas Furtado da Fonseca, Fernando Raduan, Marcus Vinícius Mota Garcia Moreno, Daniel Baumfeld,
Lateral ankle ligament injury is among the most common orthopedic injuries. The objective of this study is to present the preliminary prospective results of treatment using the "Inside-Out" variant of the fully arthroscopic Broström–Gould technique. Twenty six patients were included: 20 male and 6 female, aged 19–60 years, mean 41 years. All patients had positive "anterior drawer" and "talar tilt" tests. When necessary, cartilage injuries were treated with microfracture and arthroscopic resection for ...
Tópico(s): Sports injuries and prevention
2017 - Elsevier BV | Foot and Ankle Surgery
Olubunmi V. Akinpelu, Mario A. Mujica‐Mota, Sam J. Daniel,
The aim of this study was to systematically and quantitatively review the available evidence on the effects of type 2 diabetes mellitus on hearing function.Eligible studies were identified through searches of eight different electronic databases and manual searching of references. Articles obtained were independently reviewed by two authors using predefined inclusion criteria to identify eligible studies. Meta-analysis was performed on pooled data using Cochrane's Review Manager.Eighteen articles ...
Tópico(s): Hearing Loss and Rehabilitation
2013 - Wiley | The Laryngoscope

Yguaratã Cerqueira Cavalcanti, Paulo Anselmo da Mota Silveira Neto, Daniel Lucrédio, Tassio Vale, Eduardo Santana de Almeida, Sílvio Romero de Lemos Meira,
Duplicate bug report entries in bug trackers have a negative impact on software maintenance and evolution. This is due, among other factors, to the increased time spent on report analysis and validation, which in some cases takes over 20 min. Therefore, a considerable amount of time is lost in duplicate bug report analysis. In order to understand the possible factors that cause bug report duplication and its impact on software development, this paper presents an exploratory study in which bug tracking ...
Tópico(s): Software Testing and Debugging Techniques
2011 - Springer Science+Business Media | Software Quality Journal
Daniela Benítez‐Guerra, Cecilia Piña‐Flores, Miguel Ángel Zamora-López, Francisco J. Escalante-Padrón, Victoria Lima‐Rogel, Ana María González‐Ortiz, Marcela Guevara‐Tovar, Sofía Bernal‐Silva, Beatriz Benito‐Cruz, Fernanda Castillo‐Martínez, Luz E. Martínez‐Rodríguez, Vianney Ramírez‐Ojeda, Nallely Tello‐Martínez, Rodrigo Lomelí‐Valdez, Jack N Salto-Quintana, Sandra Cadena‐Mota, Daniel E. Noyola,
Abstract Background Respiratory syncytial virus ( RSV ) is the leading cause of severe acute respiratory infections ( ARI ) in preterm infants. The incidence of RSV ‐associated hospitalizations has not been defined in Mexico. Objectives To determine the incidence of ARI ‐ and RSV ‐associated hospitalizations in preterm infants during the first year of life. Methods Prospective cohort study of 294 preterm infants followed up through monthly telephone calls and routine outpatient visits. Hospitalized children ...
Tópico(s): Congenital Diaphragmatic Hernia Studies
2020 - Wiley | Influenza and Other Respiratory Viruses

Renata Vieira da Mota, Daniel Angelucci de Amorim, Ana Carolina Fávero, Maria Beatriz Abreu Glória, Murillo de Albuquerque Regina,
A ocorrência sistemática de dias chuvosos ou com alta nebulosidade e temperaturas ambientais elevadas prejudicam a maturação e a sanidade das uvas. Estudos recentes indicam que a alteração do ciclo de produção da videira através da poda possibilita colher uvas em épocas mais favoráveis à maturação, e com níveis de produção aceitáveis. Neste sentido, o presente trabalho teve como objetivo avaliar o perfil analítico dos vinhos de Syrah de safras de verão e inverno dos anos 2005 e 2006 produzidos em ...
Tópico(s): Postharvest Quality and Shelf Life Management
2009 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology
Tópico(s): Neonatal Respiratory Health Research
2012 - Academic Journals | Scientific Research and Essays

Daniel Michels, Amanda da Mota Silveira Rodrigues, Márcio Nakanishi, André Luiz Lopes Sampaio, Alessandra Ramos Venosa,
Numerous studies have reported an association between nasal obstruction and obstructive sleep apnea syndrome (OSAS), but the precise nature of this relationship remains to be clarified. This paper aimed to summarize data and theories on the role of the nose in the pathophysiology of sleep apnea as well as to discuss the benefits of surgical and medical nasal treatments. A number of pathophysiological mechanisms can potentially explain the role of nasal pathology in OSAS. These include the Starling ...
Tópico(s): Respiratory Support and Mechanisms
2014 - Hindawi Publishing Corporation | International Journal of Otolaryngology
Adriana Domínguez-Oliva, Ismael Hernández-Ávalos, Julio Martı́nez-Burnes, Adriana Olmos-Hernández, Antonio Verduzco-Mendoza, Daniel Mota‐Rojas,
Animal research is considered a key element in advance of biomedical science. Although its use is controversial and raises ethical challenges, the contribution of animal models in medicine is essential for understanding the physiopathology and novel treatment alternatives for several animal and human diseases. Current pandemics’ pathology, such as the 2019 Coronavirus disease, has been studied in primate, rodent, and porcine models to recognize infection routes and develop therapeutic protocols. ...
Tópico(s): Computational Drug Discovery Methods
2023 - Multidisciplinary Digital Publishing Institute | Animals

Renata Pimentel Bandeira de Melo, Jonatas Campos de Almeida, Débora Costa Viegas de Lima, C.M. Pedrosa, Fernando Jorge Rodrigues Magalhães, Adrianne Mota de Alcântara, Luiz Daniel de Barros, Rafael Felipe da Costa Vieira, João Luís Garcia, Rinaldo Aparecido Mota,
Toxoplasma gondii isolates from Brazil have a different phenotypic and genotypic pattern, with predominance of virulent isolates and recombinant genotypes, compared to the North Hemisphere. Considering that a new T. gondii genotype, non-pathogenic to mice, was previously identified from free-range chickens from the Fernando de Noronha Island, Brazil, this study aimed to identify genotypes of this parasite in tissue samples of feral cats (Felis catus) from this Brazilian Island. Anti-T. gondii IgG ...
Tópico(s): Rabies epidemiology and control
2016 - Elsevier BV | Veterinary Parasitology

Luísa Mota da Silva, Alexandra Allemand, Daniel Augusto Gasparin Bueno Mendes, Ana Cristina dos Santos, Eunice Andrè, Lauro Mera de Souza, Thales R. Cipriani, Nessana Dartora, Maria Consuelo Andrade Marques, Cristiane Hatsuko Baggio, Maria Fernanda de Paula Werner,
We evaluate the curative efficacy of the ethanolic extract (EET) of roots from Arctium lappa (bardana) in healing of chronic gastric ulcers induced by 80% acetic acid in rats and additionally studies the possible mechanisms underlying this action. Oral administration of EET (1, 3, 10 and 30mg/kg) reduced the gastric lesion area in 29.2%, 41.4%, 59.3% and 38.5%, respectively, and at 10mg/kg promoted significant regeneration of the gastric mucosa, which was confirmed by proliferating cell nuclear antigen ...
Tópico(s): Plant-derived Lignans Synthesis and Bioactivity
2012 - Elsevier BV | Food and Chemical Toxicology

Francisco R. Moreira da Mota, Daniel J. Pagano,
The aim of the present study is to contribute some knowledge of phase separation phenomena of gas–liquid turbulent flow in curved pipe and provide a basis for the development of an in-line gas–liquid separator and flow pattern conditioning device. A systematic study of gas–liquid three-phase flow in 3D helical pipes was numerically performed. Gas phase distribution in the flow through the helical pipe was analyzed for various flow parameters conditions and different pipe geometries. Experimental ...
Tópico(s): Minerals Flotation and Separation Techniques
2013 - Elsevier BV | Flow Measurement and Instrumentation

Beatriz Amaral-Moreira Mota, Fernanda Moura Lanza, Daniel Nogueira Cortez,
Objetivo Avaliar a adesão ao tratamento medicamentoso e não-medicamentoso de usuários de um serviço de atenção primária diagnosticados com hipertensão arterial sistêmica antes e após a implementação da consulta de enfermagem sistematizada. Métodos Ensaio clínico não-controlado realizado em uma Estratégia Saúde da Família de Minas Gerais, onde 14 participantes foram acompanhados por meio da assistência sistematizada de enfermagem entre os meses de outubro de 2016 e setembro de 2017. Resultados Verificou- ...
Tópico(s): Global Public Health Policies and Epidemiology
2019 - National University of Córdoba | Revista de Salud Pública
I. Mota, Daniel Wong, E. H. Sadun,
Tópico(s): Cell Adhesion Molecules Research
1968 - Elsevier BV | Life Sciences
Mario A. Mujica‐Mota, Sofia Waissbluth, Sam J. Daniel,
Background Patients receiving radiotherapy (RT) for head and neck tumors are at risk of developing sensorineural hearing loss. The objective of this study was to analyze the literature regarding sensorineural hearing loss after RT for head and neck cancer. Methods Seven databases were searched to identify eligible studies. Eligible articles were independently assessed for quality by 2 authors. Results Fourteen articles were evaluated. There was considerable heterogeneity among studies. The reported ...
Tópico(s): Head and Neck Cancer Studies
2012 - Wiley | Head & Neck
Mario A. Mujica‐Mota, Jonah Schermbrucker, Sam J. Daniel,
Eye color may be an indicator of inner ear melanin content and has been associated with hearing loss. There is controversy as to whether eye color has an effect on acquired causes of sensorineural hearing loss. This review was conducted to analyze the literature evaluating the relationship between eye color and causes of sensorineural hearing loss. Six databases were searched to identify eligible studies. Included articles were independently assessed for quality by two authors. Eighteen articles ...
Tópico(s): Olfactory and Sensory Function Studies
2014 - Elsevier BV | Hearing Research

Lícia Maria Henrique da Mota, Bóris Afonso Cruz, Claiton Viegas Brenol, Daniel Feldman Pollak, Geraldo da Rocha Castelar Pinheiro, Iêda Maria Magalhães Laurindo, Ivânio Alves Pereira, Jozélio Freire de Carvalho, Manoel Barros Bértolo, Marcelo Antônio Amaro Pinheiro, Max Victor Carioca Freitas, Nílzio Antônio da Silva, Paulo Louzada‐Júnior, Percival D. Sampaio‐Barros, Rina Dalva Neubarth Giorgi, Rodrigo Aires Corrêa Lima, Luís Eduardo Coelho Andrade,
The treatment of autoimmune rheumatic diseases has gradually improved over the last half century, which has been expanded with the contribution of biological therapies or immunobiopharmaceuticals. However, we must be alert to the possibilities of undesirable effects from the use of this class of medications. The Brazilian Society of Rheumatology (Sociedade Brasileira de Reumatologia/SBR) produced a document based on a comprehensive literature review on the safety aspects of this class of drugs, specifically ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2014 - Elsevier BV | Revista Brasileira de Reumatologia

Welber G. Quirino, Cristiano Legnani, M. Cremona, R. Reyes, Gunar Vingre da Silva Mota, Daniel E. Weibel, Maria Luiza M. Rocco,
Photoluminescence (PL) emission of 1-(3-methylphenyl)-1,2,3,4-tetrahydroquinoline-6-carboxyaldehyde-1,1 -diphenylhydrazone (MTCD) thin films was monitored as a function of UV irradiation, and it was found to decrease exponentially with the exposure time. In order to gain insight into the degradation mechanisms and evaluate the electronic structure of this organic material used with good results as hole transporting layer (HTL) in the fabrication of organic light emitting diodes (OLEDs), synchrotron radiation- ...
Tópico(s): Organic Light-Emitting Diodes Research
2008 - Brazilian Chemical Society | Journal of the Brazilian Chemical Society

Renyer A. Costa, Gabriel de A. Barros, Jonathas N. da Silva, Kélson Mota Teixeira de Oliveira, Daniel P. Bezerra, Milena Botelho Pereira Soares, Emmanoel Vilaça Costa,
In this study, guadiscine (G1) and guadiscidine (G2), 7,7-dimethylaporphine alkaloids from Guatteria friesiana, have they geometric paramaters, vibrational behavior and quantum chemical properties (HOMO-LUMO, MEP, ALIE and Fukui indices) analyzed through a theoretical view, by density functional theory (DFT), using the Becker's three-parameter hybrid exchange functional combined with the Lee–Yang–Parr correlation functional (B3LYP) and 6–311G(2d,p) and 6–311G++(2df,3p) basis sets. The obtained geometry ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2020 - Elsevier BV | Journal of Molecular Structure

Marília Freitas Calmon, Rodrigo V. Rodrigues, Carla Martins Kaneto, Ricardo P. Moura, Sabrina Daniela da Silva, Louise D. C. Mota, Daniel Guariz Pinheiro, César Torres, Alex F. Carvalho, Patrı́cia Maluf Cury, Fábio Daumas Nunes, Inês Nobuko Nishimoto, Fernando Augusto Soares, Adriana Madeira Àlvares da Silva, Luiz Paulo Kowalski, Helena Brentani, Cleslei Fernando Zanelli, Wilson A. Silva, Paula Rahal, Eloíza H. Tajara, Dirce Maria Carraro, Anamaria A. Camargo, Sandro Roberto Valentini,
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease affecting the epithelium of the oral cavity, pharynx and larynx. Conditions of most patients are diagnosed at late stages of the disease, and no sensitive and specific predictors of aggressive behavior have been identified yet. Therefore, early detection and prognostic biomarkers are highly desirable for a more rational management of the disease. Hypermethylation of CpG islands is one of the most important epigenetic mechanisms ...
Tópico(s): RNA modifications and cancer
2009 - Elsevier BV | Neoplasia

Reinaldo Nóbrega de Almeida, Flávia Raquel Santos Lucena, Camilla Vila Nova Soares Silva, Wilson da Silva Costa‐Junior, Jouse Bezerra Cavalcanti, Gerald Bosco Lindoso Couto, Luiz Lúcio Soares da Silva, Diógenes Luís da Mota, Alex Benício da Silveira, Samuel Daniel de Sousa Filho, Aldo Cezar Passilongo da Silva,
Abstract Naphthoquinones have been studied extensively due to their activity as topoisomerase inhibitors. These enzymes are critical to DNA replication in cells. β ‐Lapachone (beta‐lap) is an o ‐naphthoquinone chemically obtained from lapachol. This work results in a toxicological evaluation of beta‐lap in Wistar rats observing the following parameters: teratology, histology, hematology and serum biochemistry. The data demonstrate teratogenic action at the doses used, as well as hematological alterations ...
Tópico(s): Synthesis and Biological Evaluation
2009 - Wiley | Phytotherapy Research

João M. Batista, Silvia N. López, Jonas da Silva Mota, Kenia L. Vanzolini, Quézia B. Cass, Daniel Rinaldo, Wagner Vilegas, Vanderlan da Silva Bolzani, Massuo J. Kato, Maysa Furlan,
The resolution of the natural racemic chromane 3,4-dihydro-5-hydroxy-2,7-dimethyl-8-(3''-methyl-2''-butenyl)-2-(4'-methyl-1',3'-pentadienyl)-2H-1-benzopyran-6-carboxylic acid (1) isolated from the leaves of Peperomia obtusifolia has been accomplished using stereoselective HPLC. The absolute configuration of the resolved enantiomers was determined by the analysis of optical rotations and CD spectra. The finding of a racemic mixture instead of an enantiomerically pure metabolite raises questions about ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2008 - Wiley | Chirality

Cáris Maroni Nunes, Marina Mota Pires, Karinne Marques da Silva, Filipe Daniel Assis, Jesualdo Gonçalves Filho, Silvia Perri,
Domestic dogs are the main reservoirs of visceral leishmaniasis (VL) in urban areas; one of the control measures adopted in Brazil is the elimination of this reservoir. In order to test the relationship between the euthanasia rate of the canine reservoir and the incidence of the disease in humans, data on dog culling from the Centre for Zoonosis Control of Araçatuba, São Paulo, Brazil, during the period from 1999 to 2008 and visceral leishmaniasis human cases registered in the same period were analyzed. ...
Tópico(s): Leptospirosis research and findings
2010 - Elsevier BV | Veterinary Parasitology