Marco Monticelli, Dario Valter Conca, Edoardo Albisetti, A. Torti, Parikshit Pratim Sharma, Gururaj Rao Kidiyoor, Sara Barozzi, Dario Parazzoli, Pasquale Ciarletta, Monica Lupi, D. Petti, R. Bertacco,
Magnetic domain wall tweezers allow the application of localized and precisely quantified forces on target cells for mechanobiology studies.
Tópico(s): Erythrocyte Function and Pathophysiology
2016 - Royal Society of Chemistry | Lab on a Chip
Johnny Nguyen, Dario Valter Conca, Johannes Stein, Laura Bovo, Chris Howard, Isabel Llorente‐Garcia,
Graphite is an inexpensive material with useful electrical, magnetic, thermal, and optical properties. It is also biocompatible and used universally as a substrate. Micrometer-sized graphitic particles in solution are therefore ideal candidates for novel lab-on-a-chip and remote manipulation applications in biomedicine, biophysics, chemistry, and condensed-matter physics. However, submerged graphite is not known to be amenable to magnetic manipulation, the optimal manipulation method for such applications. ...
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2019 - National Academy of Sciences | Proceedings of the National Academy of Sciences
... Vandoni, con la collaborazione di Antonio Aloni, Fabrizio Conca, Dario Del Corno, Alessandra Gavezzotti Gara, Robert Hübner was ...
Tópico(s): Legal and Labor Studies
1979 - Böhlau Verlag | Zeitschrift der Savigny-Stiftung für Rechtsgeschichte Romanistische Abteilung
Luis Abad Mas, Rosalía Ruiz Andrés, Francisca Moreno Madrid, María Ángeles Sirera Conca, Marcel Cornesse, Iván Darío Delgado Mejía, Máximo Carlos Etchepareborda Simonini,
Introduccion. Las propuestas de tratamiento del trastorno por deficit de atencion/hiperactividad (TDAH) son variadas; sin embargo, existe poca cantidad de material publicado para mejorar el rendimiento de los mecanismos atencionales, de control inhibitorio, de flexibilidad cognitiva y de memoria de trabajo en estos ninos. Consideramos que la consolidacion de un modelo de trabajo eficaz en el tratamiento de personas con TDAH requiere una comprension exhaustiva de los sindromes que estan involucrados ...
Tópico(s): Psychological Treatments and Disorders
2011 - Viguera Publishers | Revista de Neurología
Rossella Castagna, Alessandro Bertucci, Eko Adi Prasetyanto, Marco Monticelli, Dario Valter Conca, Matteo Massetti, Parikshit Pratim Sharma, Francesco Damin, Marcella Chiari, Luisa De Cola, R. Bertacco,
High-performing hybridization platforms fabricated by reactive microcontact printing of DNA probes are presented. Multishaped PDMS molds are used to covalently bind oligonucleotides over a functional copolymer (DMA-NAS-MAPS) surface. Printed structures with minimum width of about 1.5 μm, spaced by 10 μm, are demonstrated, with edge corrugation lower than 300 nm. The quantification of the immobilized surface probes via fluorescence imaging gives a remarkable concentration of 3.3 × 10(3) oligonucleotides/ ...
Tópico(s): Microfluidic and Bio-sensing Technologies
2016 - American Chemical Society | Langmuir
Giovanni Tarantino, Patrizia Colicchio, Paolo Conca, Carmine Finelli, Matteo Nicola Dario Di Minno, Marianna Tarantino, Domênico Capone, Fabrizio Pasanisi,
Obesity is a leading risk factor for metabolic syndrome whose further expression is non-alcoholic fatty liver disease. Metabolic syndrome is associated with a proinflammatory state that contributes to insulin resistance. Finally, a "metabolically benign obesity" that is not accompanied by insulin resistance has recently been postulated to exist.To find whether any inflammation markers were independently associated with the presence of insulin resistance, evaluating specific anthropometric, ultrasonographic ...
Tópico(s): Adipose Tissue and Metabolism
2009 - BioMed Central | Journal of Inflammation
Giovanni Tarantino, Paolo Conca, Antonio Riccio, Marianna Tarantino, Matteo Nicola Dario Di Minno, Donato Chianese, Fabrizio Pasanisi, Franco Contaldo, Francesco Scopacasa, Domênico Capone,
Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis/inflammation and fibrosis. The "benignity" of fatty liver is widely accepted but conceptually difficult to maintain because the mechanisms underlying this entity are the same ones that determine the more severe form.Findings provide evidence that iron overload is ...
Tópico(s): Liver Diseases and Immunity
2008 - BioMed Central | Journal of Translational Medicine
Giovanni Tarantino, Paolo Conca, Marianna Tarantino, Matteo Nicola Dario Di Minno, Elena Grimaldi, Donato Chianese, A Riccio, F. Scopacasa, Domênico Capone,
As the lymphotropism of hepatitis C virus (HCV) has already been ascertained, and in the light of the fact that the immune defense system is an organized network composed of functionally interrelated tissues, this study was carried out to verify the possible involvement of spleen in HCV-related chronic hepatitis. In this cross-sectional study we measured spleen longitudinal diameter by ultrasound, beta2-microglobulin serum levels and splenic artery resistivity index (SARI) by Doppler in 51 patients ...
Tópico(s): Liver Disease and Transplantation
2009 - SAGE Publishing | International Journal of Immunopathology and Pharmacology
Giovanni Tarantino, Claudia Mazzarella, Marianna Tarantino, Matteo Nicola Dario Di Minno, Paolo Conca,
Background: Tissue Polypeptide Specific antigen has recently been proposed as diagnostic marker of apoptosis in NonAlcoholic SteatoHepatitis. The aim of this study was to validate in patients suffering from NonAlcoholic SteatoHepatitis the clinical utility of this marker after different programs of weight reduction. Methods: Overweight/obese patients with visceral adiposity and liver histology compatible were assigned to a Calorically-Restricted diet ( n = 22), a Calorically-Restricted diet plus EXercise ( ...
Tópico(s): Hepatitis B Virus Studies
2009 - Hindawi Publishing Corporation | Disease Markers
Giovanni Tarantino, Paolo Conca, Manuela Ariello, Maria Vincenza Mastrolia, Matteo Nicola Dario Di Minno,
Tarantino, Giovanni; Conca, Paolo; Ariello, Manuela; Mastrolia, Maria; Dario Di Minno, Matteo Nicola Author Information
Tópico(s): Heparin-Induced Thrombocytopenia and Thrombosis
2005 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
Maria A. Pantaleo, Milena Urbini, Angela Schipani, Margherita Nannini, Valentina Indio, Antonio De Leo, Bruno Vincenzi, Antonella Brunello, Giovanni Grignani, Mariaelena Casagrande, Elena Fumagalli, Elena Conca, Maristella Saponara, Elisa Gruppioni, Annalisa Altimari, Dario de Biase, Giovanni Tallini, Gloria Ravegnini, Daniela Turchetti, Marco Seri, Andrea Ardizzoni, Paola Secchiero, Annalisa Astolfi,
SDH-deficient gastrointestinal stromal tumors (GIST) account for 20-40% of all KIT/PDGFRA-negative GIST and are due to mutations in one of the four SDH-complex subunits, with SDHA mutations as the most frequent. Here we sought to evaluate the presence and prevalence of SDHA variants in the germline lineage in a population of SDHA-deficient GIST.Germline SDHA status was assessed by Sanger sequencing on a series of 14 patients with gastric SDHA-deficient GIST.All patients carried a germline SDHA pathogenic ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
2022 - Frontiers Media | Frontiers in Oncology
Marco Monticelli, Edoardo Albisetti, D. Petti, Dario Valter Conca, Mauro Falcone, Parikshit Pratim Sharma, R. Bertacco,
In-vitro tests and analyses are of fundamental importance for investigating biological mechanisms in cells and bio-molecules. The controlled application of forces to activate specific bio-pathways and investigate their effects, mimicking the role of the cellular environment, is becoming a prominent approach in this field. In this work, we present a non-invasive magnetic on-chip platform which allows for the manipulation of magnetic particles, through micrometric magnetic conduits of Permalloy patterned ...
Tópico(s): Micro and Nano Robotics
2015 - American Institute of Physics | Journal of Applied Physics
Giovanni Tarantino, Valerio Basile, Paolo Conca, Manuela Ariello, Matteo Nicola Dario Di Minno, A Romano, Antonio Gentile, Domênico Capone,
Summary. Depression is an usual finding in patients suffering from chronic hepatitis C. Development of moderate to severe depressive symptoms occurs frequently during pegylated interferon/ribavirin treatment and is generally predicted by baseline depression scores. Furthermore, the obese patients have been found to be twice as likely to suffer from anxiety, impaired social interaction, and depression when compared with the no obese population. In order to evaluate the efficacy of a pharmacological ...
Tópico(s): Urticaria and Related Conditions
2008 - Wiley | Journal of Viral Hepatitis
Antonino Belfiore, Adele Busico, Fabio Bozzi, Silvia Brich, Elena Dallera, Elena Conca, Iolanda Capone, Annunziata Gloghini, Chiara Costanza Volpi, Antonello D. Cabras, Silvana Pilotti, Dario Baratti, Marcello Guagliò, Marcello Deraco, Shigeki Kusamura, Federica Perrone,
Background—There are currently no effective therapies for diffuse malignant peritoneal mesothelioma (DMPM) patients with disease recurrence. In this study, we investigated the biology of DMPM by analyzing the EGFR family, Axl, and MET, in order to assess the presence of cross-talk between these receptors, suggesting the effectiveness of combined targeted treatments in DMPM. Method—We analyzed a series of 22 naïve epithelioid DMPM samples from a single institute, two of which showed higher-grade malignancy (“ ...
Tópico(s): Cancer Research and Treatments
2019 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Dario Peduto, Luisa Oricchio, Gianfranco Nicodemo, Michele Crosetto, Jordi Ripoll, Pere Buxó, Marc Janeras,
Tópico(s): Cryospheric studies and observations
2020 - Springer Science+Business Media | Landslides
Giovanni Tarantino, Paolo Conca, Paolo Sorrentino, Manuela Ariello, Maria Vincenza Mastrolia, Matteo Nicola Dario Di Minno,
Tarantino, Giovanni; Conca, Paolo; Sorrentino, Paolo; Ariello, Manuela; Mastrolia, Maria; Di Minno, Matteo Nicola Dario Author Information
Tópico(s): Liver Disease and Transplantation
2005 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
C. Miele, Francesca D’Auria, Luca Manfredi, Paolo Conca, Ernesto Cimino, Rosaria Mormile, Stefania De Simone, Olga Scudiero, Marcella Savoia, Antonella Tufano, Matteo Nicola Dario Di Minno, F. Capasso, Cristina Mazzaccara,
... content. Cristina Mazzaccara, Ciro Miele, Antonella Tufano, Paolo Conca, Matteo Nicola Dario Di Minno and Filomena Capasso reviewed and edited ...
Tópico(s): Blood disorders and treatments
2024 - Wiley | Haemophilia
Ilenia Calcaterra, Antonella Tufano, Federica Strano, Paola Rufolo, Sofia Donnarumma, Vincenzina Palermo, Francesca De Ruberto, Ernesto Cimino, Cornelia Guerrino, Paolo Conca, Gabriella Iannuzzo, Matteo Nicola Dario Di Minno,
Abstract Background Limited evidence is available on management of splanchnic vein thrombosis (SVT). Objectives This study aimed to evaluate safety and efficacy of direct oral anticoagulants (DOACs) for SVT treatment. Methods Studies were systematically searched in the PubMed, Web of Science, and Scopus databases according to PRISMA guidelines. We assessed any recanalization, full recanalization, recurrence, mortality, and major bleeding as outcomes of interest. Results were reported as weighted mean prevalence ( ...
Tópico(s): Central Venous Catheters and Hemodialysis
2023 - Elsevier BV | Journal of Thrombosis and Haemostasis
Paola Magnaghi, Roberta Bosotti, Nadia Amboldi, Liviana Cozzi, Alessio Somaschini, Silvia Stacchiotti, Fabio Bozzi, Elena Tamborini, Elena Conca, Silvana Pilotti, Marco A. Pierotti, Sebastiano Di Bella, Carlo Cusi, Dario Ballinari, Arturo Galvani, Barbara Salom, Antonella Isacchi,
... Somaschini, Silvia Stacchiotti, Fabio Bozzi, Elena Tamborini, Elena Conca, Silvana Pilotti, Marco A. Pierotti, Sebastiano Di Bella, Carlo Cusi, Dario Ballinari, Arturo Galvani, Barbara Salom, Antonella Isacchi. Establishment ...
Tópico(s): Oral and Maxillofacial Pathology
2015 - American Association for Cancer Research | Cancer Research
Miriam Becker, Dario Valter Conca, Noemi Dorma, Nitesh Mistry, Elin Hahlin, Lars Frängsmyr, Marta Bally, Niklas Arnberg, Gisa Gerold,
Enteric adenoviruses have historically been difficult to grow in cell culture, which has resulted in lack of knowledge of host factors and pathways required for infection of these medically relevant viruses. Previous studies in non-intestinal cell lines showed slow infection kinetics and generated comparatively low virus yields compared to other adenovirus types. We suggest duodenum-derived HuTu80 cells as a superior cell line for studies to complement efforts using complex intestinal tissue models. ...
Tópico(s): Viral Infections and Immunology Research
2023 - American Society for Microbiology | Journal of Virology
Shigeki Kusamura, Adele Busico, Elena Conca, Iolanda Capone, Luca Agnelli, Daniele Lorenzini, Silvia Brich, Marta Angelini, Chiara Costanza Volpi, Desirè Viola Trupia, Vincenzo Lagano, Tommaso Torelli, Annunziata Gloghini, Dario Baratti, Marcello Guagliò, Massimo Milione, Marcello Deraco, Federica Perrone,
In pseudomyxoma peritonei (PMP), KRAS and GNAS mutations are frequent. We hypothesized that these mutations may contribute to the suppression of antitumor immunity: KRAS may induce GMCSF expression, while GNAS may enhance the expression of cyclic adenosine monophosphate and A2AR signaling. This study aimed to explore possible mechanisms facilitated by KRAS and GNAS mutations for escaping immune surveillance. Additionally, we looked for new potential therapeutic and prognostic targets in this rare ...
Tópico(s): Immune Cell Function and Interaction
2023 - Multidisciplinary Digital Publishing Institute | Biomedicines
Alessandro Svettini, Ileana Boggian, Dario Lamonaca, Andreas Conca,
Tópico(s): Mental Health and Psychiatry
2010 - Elsevier BV | Schizophrenia Research
Margaret Ottaviano, Marcello Curvietto, Pasquale Rescigno, Marianna Tortora, Giovannella Palmieri, Diana Giannarelli, Michele Aieta, Pasquale Assalone, Laura Attademo, Antonio Avallone, Francesco Bloise, Davide Bosso, Valentina Borzillo, Giuseppe Buono, Giuseppe Calderoni, Francesca Caputo, Giacomo Cartenì, Diletta Cavallero, Alessia Cavo, Fortunato Ciardiello, Raffaele Conca, Vincenza Conteduca, Stefano De Falco, Marco De Felice, Michelino De Laurentiis, Pietro De Placido, Sabino De Placido, Irene De Santo, Alfonso De Stefano, Carminia Maria Della Corte, Rossella Di Franco, Vincenzo Di Lauro, Antonietta Fabbrocini, Piera Federico, Lucia Festino, Pasqualina Giordano, Mario Giuliano, Cesare Gridelli, Antonio M. Grimaldi, Michela Lia, Antonella Lucia Marretta, Valentina Massa, Alessia Mennitto, Sara Merler, Valeria Merz, Carlo Messina, Marco Messina, Monica Milano, Alessandro Marco Minisini, Vincenzo Montesarchio, Alessandro Morabito, Floriana Morgillo, Brigitta Mucci, Lucia Nappi, Fabiana Napolitano, Immacolata Paciolla, Martina Pagliuca, Giuseppe Palmieri, Sara Parola, Stefano Pepe, Angelica Petrillo, Francovito Piantedosi, Luisa Piccin, Fernanda Picozzi, Erica Pietroluongo, Sandro Pignata, Veronica Prati, Vittorio Riccio, Mario Rosanova, Alice Rossi, A. Russo, Massimiliano Salati, Giuseppe Santabarbara, Andrea Sbrana, Ester Simeone, Antonia Silvestri, Massimiliano Spada, Paolo Tarantino, Paola Taveggia, Federica Tomei, Vincenzo Tortora, Dario Trapani, Claudia Trojanello, Vito Vanella, Sabrina Vari, Jole Ventriglia, Maria Grazia Vitale, Fabiana Vitiello, Caterina Vivaldi, Claudia von Arx, Francesca Zacchi, Ilaria Zampiva, Andrea Zivi, Bruno Daniele, Paolo A. Ascierto,
Background The coronavirus disease 2019 (COVID-19) pandemic has overwhelmed the health systems worldwide. Data regarding the impact of COVID-19 on cancer patients (CPs) undergoing or candidate for immune checkpoint inhibitors (ICIs) are lacking. We depicted the practice and adaptations in the management of patients with solid tumors eligible or receiving ICIs during the COVID-19 pandemic, with a special focus on Campania region. Methods This survey (25 questions), promoted by the young section of SCITO ( ...
Tópico(s): Economic and Financial Impacts of Cancer
2020 - BMJ | Journal for ImmunoTherapy of Cancer
Aniello Casoria, C. Miele, Filomena Capasso, Rosaria Mormile, Luigi Bisceglia, Riccardo Pracella, Gennaro Vecchione, Ferdinando Cirillo, I. Frangipane, Paolo Conca, Ernesto Cimino, Matteo Nicola Dario Di Minno, Antonella Tufano,
•At variance with other rare bleeding disorders, fibrinogen defects are prone to arterial and venous thrombosis, due to still partially known mechanisms, in addition to bleeding. •We report a novel missense mutation in the fibrinogen γ-chain gene (FGG) in a patient referred to our department because of a history of post-partum hemorrhages and likely hypo-dysfibrinogenemia, and in seven family members (with some members affected by arterial thrombosis and transient ischemic attack and cerebral gliosis). • ...
Tópico(s): Blood properties and coagulation
2023 - Elsevier BV | Thrombosis Research
Alessandro Svettini, Ileana Boggian, Dario Lamonaca, Leticia Lopes Basso, Andreas Conca,
Background/Objectives: Recovery from severe mental illness is related to the idea of developing potentials and regaining a valid social role even with limitations caused by illness. A whole understanding of this subjective and dynamic process is still difficult. A systematic approach to evaluate recovery in people referring to mental health services is then needed in order to test out the efficacy and real utility of currently used practices and interventions.
Tópico(s): Mental Health and Psychiatry
2011 - Thieme Medical Publishers (Germany) | Psychiatrische Praxis
Gaetano Bergamaschi, Chiara Barteselli, Virginia Del Rio, Federica Borrelli de Andreis, Ivan Pellegrino, Caterina Mengoli, Emanuela Miceli, Marta Colaneri, Valentina Zuccaro, M. Di Stefano, Raffaele Bruno, Antonio Di Sabatino,
... Cicalini, Marina Clemente, Luca Clerici, Silvia Codega, Federico Conca, Luigi Coppola, Filippo Costanzo, Maria Elisa Cremonte, Roberto ... Davide Scalvini, Yiftach Shoval, Carlo Soffiantini, Simone Soriano, Dario Spadaro, Andrea Staniscia, Debora Stefani, Federico Vai, Matteo ...
Tópico(s): Respiratory Support and Mechanisms
2022 - Wiley | British Journal of Haematology