Tim Price, Jawad Ahmed, GEOFFREY BUSCHER, Erdal Taylan, Georgios Antoniou, Robert Conquest, Chris Hansen,
... Subliminal thinking Literary criticism Euro Hypo Economist Shop Devan Nair Courses Courses Courses Courses Courses Courses Courses Courses ...
2005 - Gale Group | The Economist
CH Richards, Nicholas T. Ventham, David Mansouri, Matthew Z. Wilson, George Ramsay, CD Mackay, C. N. Parnaby, Dudley Smith, Jotaro On, Doug Speake, Gordon A. McFarlane, Y. N. Neo, Emma Aitken, Cynthia H. Forrest, Kevin Knight, Andrew McKay, Hareshdeva Devan Nair, Clancy Mulholland, J R Robertson, F. Carey, R. Steele,
Objectives Colorectal polyp cancers present clinicians with a treatment dilemma. Decisions regarding whether to offer segmental resection or endoscopic surveillance are often taken without reference to good quality evidence. The aim of this study was to develop a treatment algorithm for patients with screen-detected polyp cancers. Design This national cohort study included all patients with a polyp cancer identified through the Scottish Bowel Screening Programme between 2000 and 2012. Multivariate ...
Tópico(s): Genetic factors in colorectal cancer
2016 - BMJ | Gut
Mitja Müller, WOLFGANG MOSTERT, Michael Spivey, FRANS BANEKE, WILLIAM KELLY, Yeong Yoon Ying,
... daring Canadians Canada Food for thought Nutrition Marcus Devan Nair Comparative poverty Death penalty Evolving faith Bad business ...
2006 - Gale Group | The Economist
... General Lee Kuan Yew and stalwart union leader Devan Nair. This article reconstructs Lee and Nair's theory ...
Tópico(s): Asian Geopolitics and Ethnography
2022 - Routledge | Journal of Contemporary Asia
Kenneth A McLean, Sivesh K. Kamarajah, Emily Mills, James Glasbey, Dmitri Nepogodiev, James Glasbey, Aditya Borakati, Josh Burke, Thomas M Drake, Sivesh K. Kamarajah, Kenneth A McLean, Michael Bath, H A Claireaux, Buket Gundogan, Midhun Mohan, Praveena Deekonda, Chia Yew Kong, Holly Joyce, Lisa McNamee, Evelina Woin, Chetan Khatri, J.E.F. Fitzgerald, Ewen M. Harrison, Aneel Bhangu, Dmitri Nepogodiev, Nishkantha Arulkumaran, Samira Bell, Fiona Duthie, Jeremy Hughes, Thomas Pinkney, John R. Prowle, Toby Richards, Mark Thomas, K Dynes, Mulchand S. Patel, Prashant Patel, Catrin Wigley, Rishi Suresh, Andrew Shaw, Stefan Klimach, P Jull, David A. Evans, Ryan Preece, I. Ibrahim, Venughanan Manikavasagar, R Smith, Steven R. Brown, Praveena Deekonda, Ryan Yee Wei Teo, D P Y Sim, Aditya Borakati, Andrew Logan, Ishani Barai, H Amin, Sukrit Suresh, R. Sethi, W Gul, William Bolton, O Corbridge, L. Horne, Mark Attalla, R Morley, Caitlin Robinson, Toby Hoskins, Ross McAllister, S Lee, Y Dennis, G Nixon, Emily G. Heywood, Holly Wilson, Lauren C. Ng, S. Samaraweera, Alexandra Mills, Colin P. Doherty, Evelina Woin, Jessica Belchos, Véronique Phan, Markus Arnold, Sharaf Sheik‐Ali, Rishi Suresh, Andrea Cordaro, Emily Mills, Niels Lörch, D. Thomas, B Ibrahim, Soo Khee Chee, Thomas Ngan, Savva Pronin, Nimish Thakral, T Yeoh, Jo‐Anne Wilson, R. Goodson, P. J. Molloy, Melika Akhbari, W Gul, Rebecca Helliwell, Sarah Rees, M Al-Attar, Nathan Griffiths, Jonathan Mayes, Paul V. Thomas, Stephanie M. George, Arron AT Thind, Mike Kerr, Faraz Shafiq, Ifat Yasin, Mark M. Gallagher, Emma Sewart, Tarak Chouari, Thomas W. Gardner, N Goergen, John Hayes, Calum Macleod, Roisin McCormack, A. McKinley, Steven McKinstry, William Milligan, London Lucien Ooi, N M Rafiq, T Sammut, Elizabeth M. Sinclair, M Smith, Clayton Baker, Alex Boulton, Jorja Collins, Hannah C. Copley, Nicola Fearnhead, Hannah Fox, Tammy S. Mah, James McKenna, Vinci Naruka, Neha Nigam, Basil Nourallah, S. Perera, A Qureshi, Shamit Saggar, Lianqin Sun, X Wang, Donghui Yang, P Caroll, C Doyle, Satheesh Elangovan, A Falamarzi, Kiara Gascon Perai, Emily Greenan, D Jain, Melanie Lang‐Orsini, Shir Lynn Lim, Lisa O’Byrne, Paul F. Ridgway, Sharon Van Der Laan, J Wong, Thomas Arthur, J Barclay, PM Bradley, Claire Edwin, Emily Finch, Eri Hayashi, Marilyn Hopkins, Deborah Kelly, Michael E. Kelly, Neil McCartan, Alice Ormrod, A Pakenham, Jade Hayward, C. Hitchen, A. Kishore, Tiago Martins, J Philomen, R Rao, C. Rickards, Nancy Burns, M. Copeland, Christine M. Durand, A Dyal, Ali Ghaffar, AL Gidwani, Michael Grant, C Gribbon, Almir Adolfo Gruhn, Martin Leer, K. Ahmad, Gillian M. Beattie, Matthew Beatty, G Campbell, Gordon Donaldson, Sharon S. Graham, DaJuanicia N. Holmes, S. Kanabar, H Liu, Cameron McCann, Richard Stewart, S Vara, O Ajibola-Taylor, E J E Andah, Chizobam Ani, N M O Cabdi, G Ito, Mark R. Jones, A Komoriyama, Prashant Patel, L Titu, Melvinder Basra, P Gallogly, G Harinath, SH Leong, Akshyaya Pradhan, Imran Siddiqui, S.A.J. Zaat, Ahmed Ali, Mark Galea, Wan Limm Looi, James Ng, Gary Atkin, Arash Azizi, Zillah Cargill, Z China, J.M. Elliot, R Jebakumar, John C. Lam, Gagira Mudalige, C Onyerindu, M Renju, Veena Babu, P Hussain, Nikita Joji, B Lovett, H Mownah, B Ali, Ben Cresswell, Ajit Dhillon, Y S Dupaguntla, Chipo Hungwe, Jack Lowe‐Zinola, J C H Tsang, K Bevan, C Cardus, Anchal Duggal, Mohammad Sohrab Hossain, Michael A. McHugh, Michael J. Scott, F Chan, Roger G. Evans, E Gurung, Brenda P. Haughey, B Jacob-Ramsdale, Mike Kerr, J Lee, E McCann, Kathy M. O’Boyle, Neil Reid, Faisal Hayat, Sarah Hodgson, Richard A. Johnston, W. Schuyler Jones, M. Anwar H. Khan, Thomas Linn, Stuart Long, P Seetharam, Susan Shaman, Benjamin Smart, A. Anilkumar, Justine Davies, Julie Griffith, B Hughes, Y. Islam, Debora Kidanu, N Mushaini, Iqra Qamar, Heather A. Robinson, M. Schramm, Charlene Tan, Harry Apperley, C Billyard, Jane Blazeby, Sheila Cannon, S Carse, A. Göpfert, Angela Loizidou, J. Parkin, Emily C. Sanders, Sneha Sharma, George Slade, Richard J. Telfer, I Whybrow Huppatz, E Worley, L Chandramoorthy, Charlotte Friend, L. Harris, Prateek Jain, M J Karim, Kieran Killington, John E. McGillicuddy, C Rafferty, N Rahunathan, T Rayne,
Abstract Background The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has not been well characterized. This study aimed to evaluate the 1-year mortality rate and renal outcomes associated with postoperative AKI in a national prospective cohort. Methods This prospective multicentre, observational cohort with 1-year postoperative follow-up included adults undergoing major gastrointestinal and liver surgery across the UK and Ireland ...
Wiley
... in detail what the former President of Singapore, Devan Nair, summarizes in the foreword as the psychological torment ...
Tópico(s): Asian Studies and History
1996 - Johns Hopkins University Press | Human Rights Quarterly
Ayana R. Kumar, Aswathy R. Devan, Bhagyalakshmi Nair, Lekshmi R. Nath,
Hepatocellular carcinoma (HCC) is one of the most common solid tumours and the second leading cause of cancer-related mortality worldwide. Advanced-recurrent HCC often requires a systemic drug therapy where multi tyrosine kinase inhibitor, Sorafenib represents the first-line therapy option. But it exhibited very limited survival benefit and tumour response due to the early emergence of drug resistance and drug-related adverse effect. Immunotherapy approaches now being widely studied as an effective ...
Tópico(s): Cancer Treatment and Pharmacology
2021 - Bentham Science Publishers | Current Drug Targets
Ayana R. Kumar, Aswathy R. Devan, Bhagyalakshmi Nair, Vinod Balachandran, Lekshmi R. Nath,
Cancer immunotherapy is a rapidly evolving concept that has been given the tag "fifth pillar" of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy remain the other four pillars. This involves the stimulation of the immune system to control tumor growth and it specifically targets the neoplastic cells rather than the normal cells. Conventional chemotherapy has many limitations which include drug resistance, recurrence of cancer and severe adverse effects. Immunology ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2021 - Springer Nature | Molecular Biology Reports
Bilha Baby, Aswathy R. Devan, Bhagyalakshmi Nair, Lekshmi R. Nath,
The pandemic spread of COVID 19 caused by the novel Coronavirus (SARS-CoV- 2) produced a tremendous effect on the life of humanity across the globe. The epidemiological studies revealed the drastic spectrum of SARS-CoV 2 infection ranging from mere flu-like symptoms to severe respiratory suppression within a short period. Initially, cases have been confined in the emerging point, Wuhan, China. But, within a few months, it has spread all over 212 countries around the globe and presently has become ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Bentham Science Publishers | Infectious Disorders - Drug Targets
Aswathy R. Devan, Bhagyalakshmi Nair, Ayana R. Kumar, Lekshmi R. Nath,
Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disease. It is rapidly emerging as the frequent cause for liver transplantation with the risk of disease recurrence, even after transplantation. Clinical evidence showed an abnormally altered expression of different peroxisome proliferator-activated receptor (PPAR) isotypes (PPAR-α/γ/δ) in NAFLD with an involvement in the induction of insulin resistance, hepatic steatosis, reactive oxygen species (ROS) formation, and hepatic inflammation. ...
Tópico(s): Metabolism, Diabetes, and Cancer
2021 - Wiley | Biotechnology and Applied Biochemistry
Kristopher M. Day, Narayanan Nair, Devan Griner, Larry A. Sargent,
Liposomal bupivacaine (LB, Exparel) is a long-acting local anesthetic reported to decrease postoperative. The authors demonstrate the first safe use of LB in pediatric patients with improved pain control following pharyngoplasty.Retrospective case-control of all the patients who underwent pharyngoplasty at a tertiary craniofacial center from March 2010 to June 2016. Treatment group (TG) administered 1.3% LB and 0.5% bupivacaine and 1:200,000 epinephrine. Control group (CG) administered 0.5% lidocaine ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2018 - Lippincott Williams & Wilkins | Journal of Craniofacial Surgery
... T. Seow (with a foreword by C.K. Devan Nair): To Catch a Tartar: A Dissident in Lee ...
Tópico(s): Southeast Asian Sociopolitical Studies
1995 - Cambridge University Press | The Review of Politics
Aswathy R. Devan, K Pavithran, Bhagyalakshmi Nair, Maneesha Murali, Lekshmi R. Nath,
Transforming growth factor-beta (TGF-β) is a multifunctional cytokine that performs a dual role as a tumor suppressor and tumor promoter during cancer progression. Among different ligands of the TGF-β family, TGF-β1 modulates most of its biological outcomes. Despite the abundant expression of TGF-β1 in the liver, steatosis to hepatocellular carcinoma (HCC) progression triggers elevated TGF-β1 levels, contributing to poor prognosis and survival. Additionally, elevated TGF-β1 levels in the tumor microenvironment ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2022 - Baishideng Publishing Group | World Journal of Gastroenterology
Aswathy R. Devan, Bhagyalakshmi Nair, Ayana R. Kumar, Jaggaiah N. Gorantla, Thanatharayil Sathian Aishwarya, Lekshmi R. Nath,
: Months after WHO declared COVID-19 as a Global Public Health Emergency of International Concern, it does not seem to be flattening the curve as we are still devoid of an effective vaccine and treatment modality. Amid such uncertainty, being immune is the best strategy to defend against corona attack. As the whole world is referring back to immune-boosting grandma remedies, interest is rekindled in the Indian system of Medicine, which is gifted with an abundance of herbal medicines as well as remedies. ...
Tópico(s): Phytochemicals and Medicinal Plants
2021 - Bentham Science Publishers | Current Pharmaceutical Biotechnology
Mohith Sai Subhash Gaddipati, S Krishnaja, Akhila Gopan, Ashiema G. A. Thayyil, Amrutha S. Devan, Aswathy K Nair,
Tópico(s): Fire Detection and Safety Systems
2020 - Springer Nature | Smart innovation, systems and technologies
Bhuvaneswari Krishnamoorthy, Niamh Shepherd, William R. Critchley, Janesh Nair, Nehru Devan, Abdul Nasır, James Barnard, Rajamiyer Venkateswaran, Paul Waterworth, James E. Fildes, Nizar Yonan,
Surgical knots on the suture line provide an anchoring function, but also represent a potential source of infection and irritation on the donor leg after coronary artery bypass surgery. Knotless barbed sutures were designed to prevent knot-related complications. This study compared knot-related wound complication rates between patients receiving traditional monofilament sutures and those receiving barbed knotless sutures for closure of the donor leg. One hundred and forty-two patients were randomized ...
Tópico(s): Hemostasis and retained surgical items
2015 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Aswathy R. Devan, Ayana R. Kumar, Bhagyalakshmi Nair, Nikhil Ponnoor Anto, Amitha Muraleedharan, Bijo Mathew, Hoon Kim, Lekshmi R. Nath,
Hepatocellular carcinoma (HCC) has emerged as one of the most lethal cancers worldwide because of its high refractoriness and multi-drug resistance to existing chemotherapies, which leads to poor patient survival. Novel pharmacological strategies to tackle HCC are based on oral multi-kinase inhibitors like sorafenib; however, the clinical use of the drug is restricted due to the limited survival rate and significant side effects, suggesting the existence of a primary or/and acquired drug-resistance ...
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2021 - Multidisciplinary Digital Publishing Institute | Pharmaceuticals
Aswathy R. Devan, Bhagyalakshmi Nair, Govind K Pradeep, Roshini Alexander, Vinod Balachandran, Lekshmi R. Nath, Daniela Călina, Javad Sharifi‐Rad,
Glypican-3 (GPC-3) is predominantly found in the placenta and fetal liver, with limited expression in adult tissues. Its re-expression in hepatocellular carcinoma (HCC) and secretion into the serum highlights its potential as a diagnostic marker. GPC-3 is involved in important cellular processes such as proliferation, metastasis, apoptosis, and epithelial-mesenchymal transition through various signaling pathways including Wnt, IGF, YAP, and Hedgehog. To review the structure, biosynthesis, and post- ...
Tópico(s): Ubiquitin and proteasome pathways
2024 - BioMed Central | European journal of medical research
Aswathy R. Devan, Bhagyalakshmi Nair, Lekshmi R. Nath,
Tópico(s): Toxin Mechanisms and Immunotoxins
2022 - Tabriz University of Medical Sciences | Advanced Pharmaceutical Bulletin
Lekshmi R. Nath, Ayana R. Kumar, Aswathy R. Devan, Bhagyalakshmi Nair, R Nair,
Mucin 1 (MUC 1) is a highly glycosylated tumor-associated antigen (TAA) overexpressed in hepatocellular carcinoma (HCC). This protein plays a critical role in various immune-mediated signaling pathways at its transcriptional and post-transcriptional levels, leading to immune evasion and metastasis in HCC. HCC cells maintain an immune-suppressive environment with the help of immunesuppressive tumor-associated antigens, resulting in a metastatic spread of the disease. The development of intense immunotherapeutic ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2022 - Bentham Science Publishers | Current Cancer Drug Targets
Jasmine Baby, Aswathy R. Devan, Ayana R. Kumar, Jaggaiah N. Gorantla, Bhagyalakshmi Nair, Thanatharayil Sathian Aishwarya, Lekshmi R. Nath,
Chemopreventive approaches with food-derived phytochemicals are progressively rising as a significant aspect of tumor management and control. Herein, we have showcased the major phytoconstituents belonging to the group of flavanoid, as anti-cancer agents used for the treatment and prevention of hepatocellular carcinoma (HCC). Sorafenib is the sole drug used for the treatment of advanced HCC, but its clinical application is limited because of its severe adverse effects and drug resistance. Diet-based ...
Tópico(s): Phytochemicals and Antioxidant Activities
2021 - Wiley | Journal of Food Biochemistry
Aswathy R. Devan, Bhagyalakshmi Nair, Kanjoormana Aryan Manu, Vijayastelar B. Liju, Joel Joy Koshy, Bijo Mathew, Arun Valsan, Hoon Kim, Lekshmi R. Nath,
Hepatocellular carcinoma (HCC) is often recognized as an inflammation-linked cancer, which possesses an immunosuppressive tumor microenvironment. Curative treatments such as surgical resection, liver transplantation, and percutaneous ablation are mainly applicable in the early stage and demonstrate significant improvement of survival rate in most patients. However, 70–80% of patients report HCC recurrence within 5 years of curative treatment, representing an important clinical issue. However, there ...
Tópico(s): Immune Cell Function and Interaction
2023 - Multidisciplinary Digital Publishing Institute | Cancers
Hareshdeva Devan Nair, Bibhusal Thapa, Krishna Bhagwat,
Intercostal lung hernias can be results of trauma or surgery. True spontaneous lung hernias thought to be a result of sudden acute increase in intrathoracic pressures are extremely rare. Only 51 cases have been reported in literature over the past four-and-half decades. We report a case of spontaneous chest wall posterior-lateral lung herniation that developed in a 73-year-old following severe coughing and straining during an episode of lower respiratory tract infection. Herein we present the unusual ...
Tópico(s): Trauma Management and Diagnosis
2023 - Oxford University Press | Journal of Surgical Case Reports
Michelle Zhiyun Chen, Hareshdeva Devan Nair, Apoorva Saboo, Sharon Lee, Xinchen Gu, Sheik Mohammad Azhar Auckloo, Sandeep Tamang, Sally Jiasi Chen, Ryan William Lowe, Neil Strugnell,
Repeat colonoscopy may be required for tumour localisation. The aim of the study is to explore the clinical settings it was used and benchmark the quality of initial colonoscopy against standardized guidelines for tumour localisation, tattooing and colonoscopy reporting amongst clinicians.A retrospective study from 2016 to 2021 has been performed on patients who underwent elective colorectal cancer resections at the Northern Hospital. Patient demographics, colonoscopic and operative details were ...
Tópico(s): Gastric Cancer Management and Outcomes
2022 - Wiley | ANZ Journal of Surgery
Thomas Morris, M. Zuki Bidi, Youssef Elmarsafawi, Devan Nair, Rifat Said, Reha Tugcu, Jane Ong,
Summary Whether a cement-squeeze operation results in an annular seal depends heavily on how far the cement can penetrate and disperse in the fine channels of a partially cemented annulus. In many cases, a conventional- or microfine-cement slurry will dehydrate and bridge off before it can achieve its objectives (Nelson et al. 1990). This paper describes the use of an engineered, optimized slurry for a squeeze operation in the Duyong B-4 well, which had a perforated zone that demonstrated a low rate ...
Tópico(s): Reservoir Engineering and Simulation Methods
2006 - | SPE Drilling & Completion
Tim Scroop, Lynn Savery, Michael Barnett, John Ravenhill, Lorraine Elliott, Joseph M. Siracusa, Graeme Gill, D. E. Cox, Meg Gurry, Peter Wicks, Greg Fry, John Ciccarellie, Kelvin Rowley, Johanna Sutherland, Robert F. Miller,
... s Prison (with a foreword by C.V. Devan Nair). Yale Southeast Asia Studies Monograph 42, New Haven: ...
Tópico(s): Peacebuilding and International Security
1996 - Taylor & Francis | Australian Journal Of International Affairs
... the remarkably insightful foreword contributed by C.V. Devan Nair, who, like the author, played an important and ...
Tópico(s): Socioeconomic Development in Asia
1995 - Johns Hopkins University Press | Journal of democracy
Meena Murali, Ayana R. Kumar, Bhagyalakshmi Nair, K Pavithran, Aswathy R. Devan, Goriparthi Pradeep, Lekshmi R. Nath,
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2021 - Springer Science+Business Media | Clinical & Translational Oncology
Gayathri Mallika Sudevan Devan, Gayathri Mohanan, Gowri Krishna Ajitha, Haripriya Kavitha, Ijaz Majeed, Anjana Nalinakumari Kesavan Nair,
Objective: This study aims to assess the knowledge, attitude, and practices regarding menstrual cups use and the factors associated with it among females of the reproductive age group in an urban setting of South Kerala. Materials and methods: We conducted a cross-sectional study from December 2021 to January 2022 among females of the reproductive age group. Data was entered in MS Excel and was analyzed using Statistical Package for Social Sciences version 26.0. The significance of association was ...
Tópico(s): Ovarian function and disorders
2022 - Tehran University of Medical Sciences | Journal of Family & Reproductive Health
H. Carroll-Beard, Lu Xie, Hareshdeva Devan Nair, J. Brookes, Michael P. Vallely, John D. Smith,
Tópico(s): Infective Endocarditis Diagnosis and Management
2024 - Elsevier BV | Heart Lung and Circulation