S. J. Park, B. N. Dhanvantari,
... Search for more papers by this authorB. N. Dhanvantari, B. N. Dhanvantari Agric. Canada Res. Stn., Harrow, ON, NOR 1G0 ... Search for more papers by this authorB. N. Dhanvantari, B. N. Dhanvantari Agric. Canada Res. Stn., Harrow, ON, NOR 1G0 ...
Tópico(s): Plant Pathogenic Bacteria Studies
1994 - Wiley | Crop Science
Kishan Swaroop, Krishan P. Singh, Kanwar P. Singh,
... cultivars viz., African Star, Anjali, Bis-Bis, Chandani, Dhanvantari, Friendship, Gold Beauty, Gold Dust, Hunting Song, Mayur ( ... The analysed data indicated that six cultivars viz., Dhanvantari, Anjali, Chandani, Gold Dust, Hunting Song and African ... early flowering and two late varieties such as Dhanvantari and Neelum lohile remaining sixteen varieties may be grouped as mid season flowering cultivars. Dhanvantari was found to be special grade, whereas Gold ...
Tópico(s): Flowering Plant Growth and Cultivation
2005 - | Journal of Ornamental Horticulture
Marie‐Josée Lacombe, Chantal Mercure, Jimmy D. Dikeakos, Timothy L. Reudelhuber,
... A.M. Coates L.C. Sharpe J.C. Dhanvantari S. Snell C.R. Birch N.P. Loh ... A.M. Coates L.C. Sharpe J.C. Dhanvantari S. Snell C.R. Birch N.P. Loh ... A.M. Coates L.C. Sharpe J.C. Dhanvantari S. Snell C.R. Birch N.P. Loh ... pathway. We thank Drs. Christian Deschepper and Savita Dhanvantari for critical reading of the manuscript.
Tópico(s): Cellular transport and secretion
2004 - Elsevier BV | Journal of Biological Chemistry
... Meloidigyne incognita on tomato. Phytopathology, 65, 1332– 1335. Dhanvantari BN, 1989. Effect of seed extraction methods and ... Canadian Journal of Plant Pathology, 11, 400– 408. Dhanvantari, BN, 1993. Studies on bacterial spot of sweet ... lib.uoguelph.ca/xmlui/bitstream/handle/10214/5389 Dhanvantari BN and Brown RJ, 1993. Improved seed treatments ...
Tópico(s): Plant pathogens and resistance mechanisms
2014 - Wiley | EFSA Journal
Leonardo Guizzetti, Rebecca McGirr, Savita Dhanvantari,
... major proglucagon fragment (McGirr, R., Guizzetti, L., and Dhanvantari, S. (2013) J. Endocrinol. 217, 229-240), leading ...
Tópico(s): Pancreatic function and diabetes
2014 - Elsevier BV | Journal of Biological Chemistry
... have showed significant differences among the cultivars. Pusa Dhanvantari was found superior with respect to plant height ( ... florets open at first (3.32), while Pusa Dhanvantari was late in flowering. Among the cultivars studied, ...
Tópico(s): Flowering Plant Growth and Cultivation
2005 - | Journal of Ornamental Horticulture
Kamidi Vijaya Kumari, Madhusudhan Naidu,
... was to evaluate the efficacy of uttaravasthi with dhanvantari taila in cases of female infertility.A study ...
Tópico(s): Complementary and Alternative Medicine Studies
2013 - Moksha Publishing House | International Journal of Research in Ayurveda and Pharmacy
Ahmad Essawy, Seokwon Jo, Megan Beetch, Amber Lockridge, Eric Gustafson, Emilyn U. Alejandro,
... in αTC-1 cells (22McGirr R. Guizzetti L. Dhanvantari S. The sorting of proglucagon to secretory granules ...
Tópico(s): Carbohydrate Chemistry and Synthesis
2021 - Elsevier BV | Journal of Biological Chemistry
Laura Banks, Varinder K. Randhawa, Jessica E. Caterini, Tracey J. F. Colella, Savita Dhanvantari, Sean McMurtry, Kim A. Connelly, Lisa A. Robinson, Sonia S. Anand, Maral Ouzounian, Shelley Zieroth, Susanna Mak, Sharon E. Straus, Michelle M. Graham,
A previous review of sex, gender, and equity within cardiovascular (CV) medicine, surgery, and science in Canada has revealed parity during medical and graduate school training. The purpose of this study was to explore sex and gendered experiences within the Canadian CV landscape, and their impact on career training and progression.An environmental scan was conducted of the Canadian CV landscape, which included an equity survey using Qualtrics software.The environmental scan revealed that women remain ...
Tópico(s): Healthcare cost, quality, practices
2020 - Elsevier BV | CJC Open
Varinder K. Randhawa, Savita Dhanvantari, Kim A. Connelly,
Heart failure (HF) and diabetes mellitus (DM) confer considerable burden on the health care system. Although these often occur together, DM can increase risk of HF, whereas HF can accelerate complications of DM. HF is a clinical syndrome resulting from systolic or diastolic impairment caused by ischemic, nonischemic (eg, DM), or other etiologies. HF exists along a spectrum from stage A (ie, persons at risk of DM) to stage D (ie, refractory HF from end-stage DM cardiomyopathy [DMCM]). HF is further categorized ...
Tópico(s): Cardiovascular Function and Risk Factors
2020 - Elsevier BV | Canadian Journal of Cardiology
Muhammad Shahzeb Khan, Samar Mahmood, Safi U. Khan, Kaneez Fatima, Faisal Khosa, Garima Sharma, Erin D. Michos,
... Banks L, Randhawa V, Caterini J, Colella T, Dhanvantari S, McMurtry S, Connelly K, Robinson L, Anand ...
Tópico(s): Healthcare Systems and Challenges
2020 - Lippincott Williams & Wilkins | Circulation
Gemma A. Figtree, Karin Rådholm, Terrance D. Barrett, Vlado Perkovic, Kenneth W. Mahaffey, Dick de Zeeuw, Greg Fulcher, David R. Matthews, Wayne Shaw, Bruce Neal,
... Online publication date: 14-Apr-2021. Randhawa V, Dhanvantari S and Connelly K (2021) How Diabetes and ...
Tópico(s): Pancreatic function and diabetes
2019 - Lippincott Williams & Wilkins | Circulation
Subodh Verma, John J.V. McMurray,
... Online publication date: 1-May-2021. Randhawa V, Dhanvantari S and Connelly K (2021) How Diabetes and ...
Tópico(s): Heart Failure Treatment and Management
2019 - Lippincott Williams & Wilkins | Circulation
Norbert Frey, Benjamin Meder, Hugo A. Katus,
... T, Kiaii B, Luyt L, Wisenberg G and Dhanvantari S (2019) Dynamics of the Ghrelin/Growth Hormone ...
Tópico(s): Cardiomyopathy and Myosin Studies
2018 - Lippincott Williams & Wilkins | Circulation
Jinqiang Hou, Michael S. Kovacs, Savita Dhanvantari, Leonard G. Luyt,
Molecular imaging with positron emission tomography (PET) is an attractive platform for noninvasive detection and assessment of disease. The development of a PET imaging agent targeting the ghrelin receptor (growth hormone secretagogue receptor type 1a or GHS-R1a) has the potential to lead to the detection and assessment of the higher than normal expression of GHS-R1a in diseases such as prostate, breast, and ovarian cancer. To enable the development of 18F radiopharmaceuticals, we have designed and ...
Tópico(s): Regulation of Appetite and Obesity
2018 - American Chemical Society | Journal of Medicinal Chemistry
Rebecca Sullivan, Rebecca McGirr, Shirley L. Hu, Alice Tan, Derek Wu, Carlie L. Charron, Tyler Lalonde, Edith Arany, Subrata Chakrabarti, Leonard G. Luyt, Savita Dhanvantari,
Ghrelin and its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), are present in cardiac tissue. Activation of GHSR1a by ghrelin promotes cardiomyocyte contractility and survival, and changes in myocardial GHSR1a and circulating ghrelin track with end-stage heart failure, leading to the hypothesis that GHSR1a is a biomarker for heart failure. We hypothesized that GHSR1a could also be a biomarker for diabetic cardiomyopathy (DCM). We used two models of streptozotocin (STZ)-induced DCM: ...
Tópico(s): Diabetes Treatment and Management
2017 - Endocrine Society | Journal of the Endocrine Society
Carlie L. Charron, Jinqiang Hou, Mark McFarland, Savita Dhanvantari, Michael S. Kovacs, Leonard G. Luyt,
The ghrelin receptor, also known as the growth hormone secretagogue receptor 1a (GHS-R1a), is a G-protein-coupled receptor that is differentially expressed in healthy tissue and several cancers, including prostate, testicular, and ovarian. Selectively targeting the ghrelin receptor using fluorine-18 tagged entities would allow localization and visualization of ghrelin receptor expressing carcinomas using PET imaging. The endogenous ligand ghrelin, a 28 amino acid peptide with 3.1 nM affinity, has ...
Tópico(s): Hypothalamic control of reproductive hormones
2017 - American Chemical Society | Journal of Medicinal Chemistry
Sanjay Khare, Suneel Singh Sengar,
... 32 patients (approximately 24%) were operated in INHS Dhanvantari at free of cost with help of NPCB ( ...
Tópico(s): Corneal Surgery and Treatments
2015 - Elsevier BV | Medical Journal Armed Forces India
Gregory A.F. Douglas, Rebecca McGirr, Carlie L. Charlton, Dov B. Kagan, Lisa Hoffman, Leonard G. Luyt, Savita Dhanvantari,
Ghrelin and its receptor, the growth hormone secretagogue receptor (GHS-R), are expressed in the heart, and may function to promote cardiomyocyte survival, differentiation and contractility. Previously, we had generated a truncated analog of ghrelin conjugated to fluorescein isothiocyanate for the purposes of determining GHS-R expression in situ. We now report the generation and characterization of a far-red ghrelin analog, [Dpr(3)(octanoyl), Lys(19)(Cy5)]ghrelin (1-19), and show that it can be used ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2014 - Elsevier BV | Peptides
Rebecca McGirr, Leonardo Guizzetti, Savita Dhanvantari,
Proglucagon is expressed in pancreatic alpha cells, intestinal L cells and brainstem neurons. Tissue-specific processing of proglucagon yields the peptide hormones glucagon in the alpha cell and glucagon-like peptide (GLP)-1 and GLP-2 in L cells. Both glucagon and GLP-1 are secreted in response to nutritional status and are critical for regulating glycaemia. The sorting of proglucagon to the dense-core secretory granules of the regulated secretory pathway is essential for the appropriate secretion ...
Tópico(s): Neuropeptides and Animal Physiology
2013 - Bioscientifica | Journal of Endocrinology
Anjali Soni, Khushhali M. Pandey, Pratima Ray, B. Jayaram,
... a "Genome to Hits In Silico" strategy (called Dhanvantari) and illustrate it on Chikungunya virus (CHIKV). "Genome ...
Tópico(s): Virology and Viral Diseases
2013 - Bentham Science Publishers | Current Pharmaceutical Design
Nabeel Ahmad, Ian Welch, Robert W. Grange, Jennifer Hadway, Savita Dhanvantari, David J. Hill, Ting‐Yim Lee, Lisa Hoffman,
Abstract Background Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease that affects 1 in 3500 boys. The disease is characterized by progressive muscle degeneration that results from mutations in or loss of the cytoskeletal protein, dystrophin, from the glycoprotein membrane complex, thus increasing the susceptibility of contractile muscle to injury. To date, disease progression is typically assessed using invasive techniques such as muscle biopsies, and while there are recent reports ...
Tópico(s): Exercise and Physiological Responses
2011 - BioMed Central | BMC Musculoskeletal Disorders
Rebecca McGirr, Mark McFarland, Jillian McTavish, Leonard G. Luyt, Savita Dhanvantari,
Tópico(s): Neuropeptides and Animal Physiology
2011 - Elsevier BV | Regulatory Peptides
Terence K. Lee, Saravana R. K. Murthy, Niamh X. Cawley, Savita Dhanvantari, Stephen M. Hewitt, Hong Lou, Tracy C.M. Lau, Stephanie Ma, Thanh Huynh, Robert Wesley, Irene Oi‐Lin Ng, Karel Pacák, Ronnie T.P. Poon, Y. Peng Loh,
Metastasis is a major cause of mortality in cancer patients. However, the mechanisms governing the metastatic process remain elusive, and few accurate biomarkers exist for predicting whether metastasis will occur, something that would be invaluable for guiding therapy. We report here that the carboxypeptidase E gene (CPE) is alternatively spliced in human tumors to yield an N-terminal truncated protein (CPE-ΔN) that drives metastasis. mRNA encoding CPE-ΔN was found to be elevated in human metastatic ...
Tópico(s): Histone Deacetylase Inhibitors Research
2011 - American Society for Clinical Investigation | Journal of Clinical Investigation
Pragya, J. K. Ranjan, Brij Lal Attri, Bikash Das, Hare Krishna, Nazeer Ahmed,
... 88.33 cm), Chantiler (86.33 cm), Pusa Dhanvantari (81.67 cm), Pusa Shabnam (80.33 cm), ...
Tópico(s): Plant Physiology and Cultivation Studies
2010 - Indian Academy of Horticulture Sciences | Indian Journal of Horticulture
Rebecca McGirr, Shirley L. Hu, Siu‐Pok Yee, Michael S. Kovacs, Ting‐Yim Lee, Savita Dhanvantari,
Tópico(s): Diabetes Management and Research
2010 - Springer Science+Business Media | Molecular Imaging and Biology
Donna E. Goldhawk, Claude Lemaire, Cheryl R. McCreary, Rebecca McGirr, Savita Dhanvantari, Robert T. Thompson, René Figueredo, James Koropatnick, Paula J. Foster, Frank S. Prato,
Molecular imaging with magnetic resonance imaging (MRI) may benefit from the ferrimagnetic properties of magnetosomes, membrane-enclosed iron biominerals whose formation in magnetotactic bacteria is encoded by multiple genes. One such gene is MagA, a putative iron transporter. We have examined expression of MagA in mouse neuroblastoma N2A cells and characterized their response to iron loading and cellular imaging by MRI. MagA expression augmented both Prussian blue staining and the elemental iron ...
Tópico(s): Electrical and Bioimpedance Tomography
2009 - SAGE Publishing | Molecular Imaging
Babak Behnam Azad, Vanessa Rota, Daniel Breadner, Savita Dhanvantari, Leonard G. Luyt,
Novel Glucagon-Like Peptide-1 (GLP-1) derivatives containing the metal chelator DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) and naturally occurring Indium (113/115In) were prepared using solid-phase Fmoc methods. All synthesized peptides contained d-Ala-8, a modification known to improve resistance towards degradation by dipeptidyl peptidase-IV. The effect of increased distance between DOTA and the peptide chain was investigated using an (aminoethyl) ethoxy acetyl linker, in order ...
Tópico(s): Neuroendocrine Tumor Research Advances
2009 - Elsevier BV | Bioorganic & Medicinal Chemistry
Joo Ho Tai, Binh Nguyen, R. Glenn Wells, Michael S. Kovacs, Rebecca McGirr, Frank S. Prato, Timothy G. Morgan, Savita Dhanvantari,
We are combining nuclear medicine with molecular biology to establish a sensitive, quantitative, and tomographic method with which to detect gene expression in pancreatic islet cells in vivo. Dual-isotope SPECT can be used to image multiple molecular events simultaneously, and coregistration of SPECT and CT images enables visualization of reporter gene expression in the correct anatomic context. We have engineered pancreatic islet cell lines for imaging with SPECT/CT after transplantation under ...
Tópico(s): Congenital heart defects research
2007 - Society of Nuclear Medicine and Molecular Imaging | Journal of Nuclear Medicine
Damien Coudreuse, Hendrik C. Korswagen,
... receptors and cargo molecules into the forming vesicle(Dhanvantari and Loh, 2000). The existence of such a ...
Tópico(s): Fibroblast Growth Factor Research
2006 - The Company of Biologists | Development