Diego López-Rodríguez, Diego Gella, Kiwing To, Diego Maza, Ángel Garcimartín, Iker Zuriguel,
We present experimental results of the effect of the hopper angle on the clogging of grains discharged from a two-dimensional silo under gravity action. We observe that the probability of clogging can be reduced by three orders of magnitude by increasing the hopper angle. In addition, we find that for very large hopper angles, the avalanche size ($\ensuremath{\langle}s\ensuremath{\rangle}$) grows with the outlet size ($D$) stepwise, in contrast to the case of a flat-bottom silo for which $\ensuremath{\ ...
Tópico(s): Landslides and related hazards
2019 - American Physical Society | Physical review. E
V. Costanzo‐Alvarez, Milagrosa Aldana, Germán Bayona, Diego López-Rodríguez, Joan Marie Blanco,
Abstract We have carried out rock magnetic characterizations of different lithofacies along the stratigraphic well Saltarín 1A, in order to learn about the various diagenetic events that could have affected the Miocene sequence of the Llanos foreland basin (Colombia). Thermomagnetic and low-temperature susceptibility measurements performed on some selected samples were complemented with analyses of Scanning Electron Microscopy (SEM), Energy Dispersive X-ray (EDX) and isothermal remanent magnetization ( ...
Tópico(s): Geological and Geochemical Analysis
2012 - Geological Society of London | Geological Society London Special Publications
Viviana Raoch, Fernando Rodríguez‐Pascual, Vanesa López-Martínez, Diana Medrano-Andrés, Manuel Rodríguez‐Puyol, Santiago Lamas, Diego Rodríguez‐Puyol, Susana López‐Ongil,
Endothelial function depends on the equilibrium in the synthesis of vasoactive endothelial factors. It is well known that endothelin and nitric oxide (NO) exhibit reciprocal regulation. We assessed the ability of NO to regulate endothelin-converting enzyme-1 (ECE-1) expression in vascular endothelial cells.Bovine aortic endothelial cells were incubated with 2 different NO donors as well as with a cyclic-GMP analog, dibutyryl-cGMP (dB-cGMP). ECE-1 protein content and mRNA expression were evaluated by ...
Tópico(s): Receptor Mechanisms and Signaling
2011 - Lippincott Williams & Wilkins | Arteriosclerosis Thrombosis and Vascular Biology
A. García-Rodríguez, Diego Granados-López, S. García-Rodríguez, M. Díez-Mediavilla, Cristina Alonso‐Tristán,
In this study, ten-minute meteorological data-sets recorded at Burgos, Spain, are used to develop models of Photosynthetic Active Radiation (PAR) following two different procedures: multilinear regression and Artificial Neural Networks. Ten Meteorological Indices (MIs) are chosen as inputs to the models: clearness index (kt), diffuse fraction (kd), direct fraction (kb), Perez's clear sky index (ɛ), brightness index (Δ), cloud cover (CC), air temperature (T), pressure (P), solar azimuth cosine (cosZ), and horizontal ...
Tópico(s): Urban Heat Island Mitigation
2021 - Elsevier BV | Agricultural and Forest Meteorology
Andrés Cañada-Barcala, Diego Rodríguez-Llorente, Laura López, Pablo Navarro, Elisa Hernández, V. Ismael Águeda, Silvia Álvarez-Torrellas, Juan Carlos Parajó, Sandra Rivas, Marcos Larriba,
Furfural comes from lignocellulosic biomass that, together with its derived products, has many useful applications in several industries. Furfural is usually obtained via pentose dehydration using a biphasic reactor to extract furfural in situ from its reaction medium. However, the conventional solvents used so far, mainly toluene and methyl isobutyl ketone (MIBK), are harmful to health and the environment. Therefore, hydrophobic natural solvents have been successfully tested in this work to improve ...
Tópico(s): Supercapacitor Materials and Fabrication
2021 - American Chemical Society | ACS Sustainable Chemistry & Engineering
Elena Alcalde‐Estévez, Patricia Sosa, Ana Asenjo‐Bueno, Patricia Plaza, Gemma Olmos, Manuel Naves‐Díaz, Diego Rodríguez‐Puyol, Susana López‐Ongil, María Piedad Ruiz‐Torres,
Abstract Uraemic toxins increase in serum parallel to a decline in the glomerular filtration rate and the development of sarcopenia in patients with chronic kidney disease (CKD). This study analyses the role of uraemic toxins in sarcopenia at different stages of CKD, evaluating changes in the muscular regeneration process. Cultured C 2 C 12 cells were incubated with a combination of indoxyl sulphate and p-cresol at high doses (100 µg/mL) or low doses (25 µg/mL and 10 µg/mL) resembling late or early ...
Tópico(s): Muscle and Compartmental Disorders
2021 - Nature Portfolio | Scientific Reports
Patricia Martínez‐Miguel, Diana Medrano-Andrés, Mercedes Griera-Merino, Alberto Órtiz, Manuel Rodríguez‐Puyol, Diego Rodríguez‐Puyol, Susana López‐Ongil,
To analyse the ability of TWEAK to modify the endothelin system, particularly endothelin-1 (ET-1) and endothelin-converting enzyme-1 (ECE-1), studying the intracellular mechanisms implied. TNF-like weak inducer of apoptosis (TWEAK) is a member of TNF superfamily; it has different biological functions such as inflammation, angiogenesis, proliferation, and apoptosis. TWEAK and fibroblast growth-factor-inducible 14 are expressed in different cell types, including endothelial and smooth muscle cells. Despite ...
Tópico(s): Nuclear Receptors and Signaling
2016 - Oxford University Press | Cardiovascular Research
Diego Salazar, Alexander Rodríguez‐López, Angélica María Herreño, Hector Barbosa, Juliana Herrera, Andrea Ardila, George E. Barreto, Janneth González, Carlos Javier Alméciga-Díaz,
Mucopolysaccharidosis (MPS) is a group of lysosomal storage diseases (LSD), characterized by the deficiency of a lysosomal enzyme responsible for the degradation of glycosaminoglycans (GAG). This deficiency leads to the lysosomal accumulation of partially degraded GAG. Nevertheless, deficiency of a single lysosomal enzyme has been associated with impairment in other cell mechanism, such as apoptosis and redox balance. Although GAG analysis represents the main biomarker for MPS diagnosis, it has several ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2015 - Elsevier BV | Molecular Genetics and Metabolism
Patricia Martínez‐Miguel, José Manuel Valdivielso, Diana Medrano-Andrés, Pablo Román‐García, José Luis Cano-Peñalver, Manuel Rodríguez‐Puyol, Diego Rodríguez‐Puyol, Susana López‐Ongil,
Despite the presence of vitamin D receptor (VDR) in endothelial cells, the effect of vitamin D on endothelial function is unknown. An unbalanced production of vasoactive endothelial factors such as nitric oxide (NO) or endothelin-1 (ET-1) results in endothelial dysfunction, which can alter the normal cardiovascular function. Present experiments were devoted to assess the effect of active vitamin D (calcitriol) on the synthesis of endothelial vasoactive factors. The results were that, in cells, calcitriol ...
Tópico(s): Hormonal Regulation and Hypertension
2014 - American Physiological Society | AJP Endocrinology and Metabolism
Diego Martínez, Jesús Rodríguez‐López, José L. Torres,
This paper studies the impact of information and communication technologies (ICT) on US economic growth using a dynamic general equilibrium approach. A production function with six different capital inputs is used, three of them corresponding to ICT assets and the other three to non-ICT assets. The technological change embedded in hardware equipment is found to be the main leading non-neutral force in US productivity growth, accounting for about one quarter of total growth during the period 1980– ...
Tópico(s): Regional Economics and Spatial Analysis
2009 - Elsevier BV | Information Economics and Policy
Patricia Martínez‐Miguel, Viviana Raoch, Carlos Zaragoza, José Manuel Valdivielso, Manuel Rodríguez‐Puyol, Diego Rodríguez‐Puyol, Susana López‐Ongil,
The aim of our study was to analyze the relationships between atherosclerosis and endothelin-converting enzyme-1 (ECE-1). Four-week-old C57BL/6J [wild-type (WT)] and apolipoprotein E-deficient (apoE) mice were fed with a standard or Western-type fat diet for 8 wks. ApoE showed atherosclerotic lesions in the aorta, higher blood pressure and vascular lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) protein content than WT. ApoE showed a significant increase in ECE-1 protein content and mRNA ...
Tópico(s): Nitric Oxide and Endothelin Effects
2008 - Elsevier BV | Journal of Lipid Research
Diego Martínez, Jesús Rodríguez‐López, José L. Torres,
This paper studies the impact of the information and communication technologies (ICT) on economic growth in Spain using a dynamic general equilibrium approach. Contrary to previous works, we use a production function with six different capital inputs, three of them corresponding to ICT assets. Calibration of the model suggests that the contribution of ICT to Spanish productivity growth is very relevant, whereas the contribution of non-ICT capital has been even negative. Additionally, over the sample ...
Tópico(s): Regional Economics and Spatial Analysis
2007 - Elsevier BV | Journal of Macroeconomics
Borja Nogales, Iván Vidal, Diego López, Juan Rodríguez, Jaime García-Reinoso, Arturo Azcorra,
Management and orchestration of virtual resources and functions, commonly referred to as MANO, are key functionalities of NFV environments. This article describes the design and deployment of the NFV MANO platform of 5TONIC, the open research and innovation laboratory on 5G technologies founded by Telefonica and IMDEA Networks. This NFV MANO platform provides 5TONIC trials and experiments with access to a functional production-like NFV environment, enabling experimentation with novel NFV products ...
Tópico(s): Advanced MIMO Systems Optimization
2019 - Institute of Electrical and Electronics Engineers | IEEE Communications Magazine
Sergio Olarte-Avellaneda, Jacobo Cepeda Del Castillo, Felipe Rojas-Rodríguez, Oscar F. Sánchez, Alexander Rodríguez‐López, Diego A. Súarez, Luz Mary Salazar, Carlos Javier Alméciga-Díaz,
Mucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the gene encoding for the enzyme N-acetylgalactosamine-6-sulfate sulfatase (GALNS), leading to lysosomal accumulation of keratan sulfate (KS) and chondroitin-6-sulfate. In this study, we identified and characterized bromocriptine (BC) as a novel PC for MPS IVA. BC was identified through virtual screening and predicted to be docked within the active cavity of GALNS in a similar conformation to that observed for ...
Tópico(s): Glycosylation and Glycoproteins Research
2020 - American Chemical Society | ACS Medicinal Chemistry Letters
Danny Rodríguez López, Diego A. Ahumada, Consuelo Díaz-Moreno, Jairo A. Guerrero,
To assess potential exposure of bees to chemicals contaminants, pesticides and other management practices of local beekeepers and farmers, four Colombian regions were surveyed and residue concentrations were determined on some pesticides used and others banned for honey. A total of 61 honey samples were collected and analyzed during 2011. Residual levels of selected insecticides, fungicides and acaricides were determined by a multiresidue method, using gas chromatography with nitrogen phosphorous ...
Tópico(s): Bee Products Chemical Analysis
2013 - Elsevier BV | Food Control
Javier Garcia-Zúbia, Ingvar Gustavsson, Unai Hernández‐Jayo, Pablo Orduña, Ignacio Angulo, Luis Rodriguez, Diego López–de–Ipiña,
The paper presents the results of applying the VISIR (Virtual Instrument Systems in Reality) system at the course of analog electronics for various degrees of the Faculty of Engineering of the University of Deusto (Spain). The efficiency of the VISIR had been monitored during past three years. Studentsâ?? feedback was collected and analyzed. The research shows: 1) VISIR system is functional and useful learning instrument; 2) teacher experience at VISIR plays crucial role in its integration into student ...
Tópico(s): Sensor Technology and Measurement Systems
2011 - | International Journal of Online and Biomedical Engineering (iJOE)
V. Costanzo‐Alvarez, Rosa Devesa Rey, Milagrosa Aldana, María Teresa Barral, Diego López-Rodríguez, Belkys Andrade,
Tópico(s): Heavy metals in environment
2017 - Springer Science+Business Media | Environmental Earth Sciences
Ana da Silva, V. Costanzo‐Alvarez, Nuri Hurtado, Milagrosa Aldana, Germán Bayona, Oswaldo Guzmán, Diego López-Rodríguez,
Tópico(s): Geomagnetism and Paleomagnetism Studies
2010 - Springer Science+Business Media | Studia Geophysica et Geodaetica
Pablo Navarro, Elisa Hernández, Diego Rodríguez-Llorente, Ignacio Maldonado-López, Rubén Santiago, Cristian Moya, Alejandro Belinchón, Marcos Larriba, José Palomar,
In this work, eight CO2-derived cyclic carbonates, namely ethylene carbonate (Eth-C), propylene carbonate (Pro-C), butylene carbonate (But-C), hexylene carbonate (Hex-C), cyclohexene carbonate (Cyc-C), styrene carbonate (Sty-C), glycerol carbonate (Gly-C) and (Chloromethyl)ethylene carbonate (Chl-C) were evaluated as solvents to mitigate residual aromatic content in liquid fuels by envisioning an efficient liquid–liquid extraction process, using benzene, thiophene and pyrrole as benchmark compounds for dearomatization, ...
Tópico(s): Ionic liquids properties and applications
2022 - Elsevier BV | Fuel
António Rivero‐Juarez, Mario Frías, Diego Rodríguez-Cano, Francisca Cuenca-López, Antonio Rivero,
Tópico(s): Liver Disease and Transplantation
2016 - Oxford University Press | Clinical Infectious Diseases
Aránzazu Chamorro‐Jorganes, María T. Grande, Beatriz Herránz, Mirjana Jerkić, Mercedes Griera, González Núñez, Eugenio Santos, Diego Rodríguez‐Puyol, José M. López‐Novoa, Manuel Rodríguez‐Puyol,
The aim of the present experiments was to evaluate the differences in arterial pressure between H-Ras lacking mice and control mice and to analyze the mechanisms involved in the genesis of the differences. H-Ras lacking mice and mouse embryonic fibroblasts from these animals were used. Blood pressure was measured using 3 different methods: direct intraarterial measurement in anesthetized animals, tail-cuff sphygmomanometer, and radiotelemetry. H-Ras lacking mice showed lower blood pressure than ...
Tópico(s): Receptor Mechanisms and Signaling
2010 - Lippincott Williams & Wilkins | Hypertension
Ana Olivera, Santiago Lamas, Diego Rodríguez‐Puyol, José M. López‐Novoa,
Tópico(s): Acute Kidney Injury Research
1989 - Elsevier BV | Kidney International
de Arriba G, Barrio, Ana Olivera, Diego Rodríguez‐Puyol, José M. López‐Novoa,
Tópico(s): Renin-Angiotensin System Studies
1988 - Elsevier BV | Journal of Laboratory and Clinical Medicine
Carlos Caramelo, Dolores Fernandez-Muñoz, Juan Carlos Santos, Alicia Blanchart, Diego Rodríguez‐Puyol, José M. López‐Novoa, L Hernando,
General and splanchnic hemodynamics (radioactive microspheres), renal function, spontaneous and histamine-mediated vasopermeability and albumin distribution space were studied in conscious control and nonascitic cirrhotic rats, before and after a moderate and sustained saline infusion (3% of body weight per 30 min + repletion of urinary losses). In basal conditions, cirrhotic rats showed lower fractional sodium excretion than did control rats (0.09 +/- 0.01 vs. 0.15 +/- 0.01%, p less than 0.005). In addition, ...
Tópico(s): Blood Pressure and Hypertension Studies
1986 - Lippincott Williams & Wilkins | Hepatology
María Isabel Morales‐Casado, Agustín Julián-Jiménez, Fernando Moreno-Alonso, Eder Valente-Rodríguez, Diego López-Muñoz, José Saura-Montalbán, Rafael Cuena,
To analyse and compare procalcitonin (PCT) and C-reactive protein (CRP) as tools for detecting bacterial meningitis (BM) in the elderly (>74 years of age).A prospective, observational, descriptive, analytical study of 220 consecutive patients aged ≥1year and diagnosed with acute meningitis in an emergency department between September 2009 and July 2014.A total of 220 patients (136 [62%] male) were studied. The mean age was 30±26years, with BM being diagnosed in 17/83 patients from 1 to 14years of age, 32/ ...
Tópico(s): Sepsis Diagnosis and Treatment
2015 - Elsevier BV | Enfermedades Infecciosas y Microbiología Clínica
Diego González‐Aguilera, Luis López-Fernández, Pablo Rodríguez‐Gonzálvez, Diego Guerrero, David Hernández‐López, Fabio Remondino, F. Menna, Erica Nocerino, I. Toschi, Andrea Ballabeni, Marco Gaiani,
Abstract. Photogrammetry is currently facing some challenges and changes mainly related to automation, ubiquitous processing and variety of applications. Within an ISPRS Scientific Initiative a team of researchers from USAL, UCLM, FBK and UNIBO have developed an open photogrammetric tool, called GRAPHOS (inteGRAted PHOtogrammetric Suite). GRAPHOS allows to obtain dense and metric 3D point clouds from terrestrial and UAV images. It encloses robust photogrammetric and computer vision algorithms with ...
Tópico(s): Robotics and Sensor-Based Localization
2016 - Copernicus Publications | The international archives of the photogrammetry, remote sensing and spatial information sciences/International archives of the photogrammetry, remote sensing and spatial information sciences
Diego González‐Aguilera, Luis López-Fernández, Pablo Rodríguez‐Gonzálvez, Diego Guerrero, David Hernández‐López, Fabio Remondino, F. Menna, Erica Nocerino, I. Toschi, Andrea Ballabeni, Marco Gaiani,
Photogrammetry is currently facing some challenges and changes mainly related to automation, ubiquitous processing and variety of applications. Within an ISPRS Scientific Initiative a team of researchers from USAL, UCLM, FBK and UNIBO have developed an open photogrammetric tool, called GRAPHOS (inteGRAted PHOtogrammetric Suite). GRAPHOS allows to obtain dense and metric 3D point clouds from terrestrial and UAV images. It encloses robust photogrammetric and computer vision algorithms with the following ...
Tópico(s): Remote Sensing and LiDAR Applications
2016 - Copernicus Publications | The international archives of the photogrammetry, remote sensing and spatial information sciences/International archives of the photogrammetry, remote sensing and spatial information sciences
María Cristina González-Lozano, Lia Celina Méndez-Rodríguez, Diego López-Veneroni, Alfonso V. Botello,
Para evaluar la calidad de los sedimentos recientes del area portuaria y costera de Salina Cruz, Oaxaca, Mexico, principal centro de abastecimiento de petroleo y productos refinados del litoral Pacifico mexicano, se caracterizaron los principales contaminantes indicativos de actividad petrolera: hidrocarburos aromaticos (HA), material organico extraible (MOE) y metales pesados, asi como su relacion con la toxicidad y granulometria. El estudio se realizo en tres periodos climaticos: secas, lluvias ...
Tópico(s): Geography and Environmental Studies in Latin America
2006 - Associação Interciencia | Interciencia
María Bravo García‐Morato, Francisco Javier Aracil Santos, Alejandro C. Briones, Alfonso Blázquez Moreno, Ángela del Pozo Maté, Ángeles Domínguez‐Soto, Maria J. Merino, Lucía del Pino Molina, Juan Manuel Torres, Ana V. Marín, Elena Vallespín García, M. F. Prieto Rodríguez, Diego Plaza López Sabando, Anaïs Jiménez-Reinoso, Yasmina Mozo, Francisco José Sanz-Santaeufemia, R. de Lucas‐Laguna, Paula P. Cárdenas, Laura Polo, María Coronel Díaz, Mar Valés‐Gómez, Ernesto Roldán Santiago, A Cerdán, Julián Nevado Blanco, Ángel L. Corbí, Hugh T. Reyburn, José R. Regueiro, Eduardo López‐Granados, Rebeca Rodríguez Pena,
Primary immunodeficiencies (PIDs) are a group of around 300 rare and usually monogenic disorders, mostly caused by point mutations.1 Uniparental disomy (UPD) is a condition in which both copies of a chromosome or chromosomal region are inherited from the same progenitor.2 Uniparental isodisomy (UPID) is a type of UPD caused by nondisjunction errors in one of the parental gametes in meiosis II. UPID can be pathogenic, either because of imprinting defects or inheritance of a recessive condition from ...
Tópico(s): Tumors and Oncological Cases
2018 - Elsevier BV | Journal of Allergy and Clinical Immunology
Gemma Olmos, José M. Muñoz‐Félix, Inés Mora, Anton Muller, María Piedad Ruiz‐Torres, José M. López‐Novoa, Diego Rodríguez‐Puyol,
Abstract Renal fibrosis and anaemia are two of the most relevant events in chronic kidney disease. Fibrosis is characterized by the accumulation of extracellular matrix proteins in the glomeruli and tubular interstitium. Anaemia is the consequence of a decrease in erythropoietin production in fibrotic kidneys. This work analyses the possibility that the accumulation of abnormal collagens in kidney interstitium could be one of the mechanisms responsible for erythropoietin decreased synthesis. In ...
Tópico(s): Renal cell carcinoma treatment
2017 - Wiley | Journal of Cellular and Molecular Medicine