Produção Nacional
Revisado por pares
Renata Garbellini Duft, Alex Castro, Ivan Luiz Padilha Bonfante, Diego Trevisan Brunelli, Mara Patrícia Traina Chacon‐Mikahil, Cláudia Regina Cavaglieri,
Obesity is associated with comorbidities related to metabolic disorders due to excess of adipose tissue. Physical exercise has a major role in the prevention of obesity. Combined training (CT), in particular, has been shown to improve markers of health. In this study, we used 1H NMR-based metabolomics to investigate changes in the metabolism of obese men after 24 weeks of CT. Twenty-two obese (body mass index 31 ± 1.4 kg/m2), middle-aged men (48.2 ± 6.1 years) were randomly assigned to a control group ( ...
Tópico(s): Cardiovascular and exercise physiology
2017 - American Chemical Society | Journal of Proteome Research
Produção Nacional
Revisado por pares
Ivan Luiz Padilha Bonfante, Mara Patrícia Traina Chacon‐Mikahil, Diego Trevisan Brunelli, Arthur Fernandes Gáspari, Renata Garbellini Duft, Wendell Arhur Lopes, Valéria Bonganha, Cleiton Augusto Libardi, Cláudia Regina Cavaglieri,
Abstract The effects of training on FNDC5/irisin and its association with fitness and metabolic marker improvements induced by training have been poorly investigated in humans. Thus, the present study assessed the effects of combined training (CT) on FNDC5/irisin levels, metabolic markers and fitness adaptations in obese men. Middle‐age obese men (age 49.13 ± 5.75, body mass index (BMI) 30.86 ± 1.63) were randomly distributed in the CT group ( n = 12) and control group (CG n = 10). The CT consisted of strength ...
Tópico(s): Exercise and Physiological Responses
2017 - Taylor & Francis | European Journal of Sport Science
Produção Nacional
Ivan Luiz Padilha Bonfante, Mara Patrícia Traina Chacon‐Mikahil, Diego Trevisan Brunelli, Arthur Fernandes Gáspari, Renata Garbellini Duft, Alexandre G. Oliveira, Tiago Gomes Araújo, Mário J.A. Saad, Cláudia Regina Cavaglieri,
Objective: Thus, the aim of this study was to compare if higher or smaller fibronectin type 3 domain-containing protein 5 (FNDC5)/irisin levels are associated with inflammatory and metabolic markers, caloric/macronutrient intake, physical fitness and type 2 diabetes mellitus (T2DM) risk in obese middle-aged men, and also to correlate all variables analyzed with FNDC5/irisin. Subjects and methods: On the basis of a cluster study, middle-aged obese men (IMC: 31.01 ± 1.64 kg/m2) were divided into groups ...
Tópico(s): Thermoregulation and physiological responses
2017 - Brazilian Society of Endocrinology and Metabolism | Archives of Endocrinology and Metabolism
Produção Nacional
Revisado por pares
Francine Novack Victoria, Eder J. Lenardão, Lucielli Savegnago, Gelson Perin, Raquel G. Jacob, Diego Alves, Wladimir Padilha da Silva, Amanda de Souza da Motta, Patrícia da Silva Nascente,
Essential oil (EO) of the leaves of Eugenia uniflora L. (Brazilian cherry tree) was evaluated for its antioxidant, antibacterial and antifungal properties. The acute toxicity of the EO administered by oral route was also evaluated in mice. The EO exhibited antioxidant activity in the DPPH, ABTS and FRAP assays and reduced lipid peroxidation in the kidney of mice. The EO also showed antimicrobial activity against two important pathogenic bacteria, Staphylococcus aureus and Listeria monocytogenes, and ...
Tópico(s): Phytochemicals and Antioxidant Activities
2012 - Elsevier BV | Food and Chemical Toxicology
Produção Nacional
Revisado por pares
Bruna Silvatti, Thaís Marques Granato, Pedro Nacib Jorge‐Neto, Marta Maria Círchia Pinto Luppi, Laura Reisfeld, Paloma Canedo Henrique, Fabiana Lúcia André Padilha, Roberta Ferreira Leite, João Diego de Agostini Losano, Giulia Kiyomi Vechiato Kawai, M. Nichi, Cristiane Schilbach Pizzutto,
In ex situ conditions, little is known about the reproductive biology of meerkats. The aim of present study was to describe the morphological aspects of male genital organs and accessory glands using macroscopic evaluation, ultrasonography, and radiography, as well as describing semen characteristics post-electroejaculation. The results indicated anatomical characteristics of meerkats are very similar to those of cats, having a prostate, accessory bulbourethral glands, and an elongated and radiopaque ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2020 - Elsevier BV | Animal Reproduction Science
Produção Nacional
Revisado por pares
Beatriz Vieira, Nathalia B. Padilha, Nelson M. Nascimento, Gelson Perin, Diego Alves, Ricardo F. Schumacher, Eder J. Lenardão,
A simple and rapid method to synthesize imidazo[1,2-a]pyridines starting from 2-aminopyridine and 2bromoacetophenone derivatives under ultrasonic irradiation was developed.This protocol tolerates a wide range of 2-bromoacetophenone derivatives to produce a variety of imidazo[1,2-a]pyridines in good to excellent yields.Additionally, the one-pot preparation of 3-(organylselanyl)imidazo[1,2-a]pyridines via a sequential method is presented.In this case, different diorganyl diselenides were used as starting ...
Tópico(s): Synthesis and biological activity
2019 - ARKAT USA, Inc. | ARKIVOC
Produção Nacional
Revisado por pares
Igor Gomes Padilha, Ana Paula Alves Fonseca, Ana L. M. Pettengill, Diego Cardoso Fragoso, Felipe Torres Pacheco, Renato Hoffmann Nunes, Antônio Carlos Martins Maia, Antônio José da Rocha,
Tópico(s): Rheumatoid Arthritis Research and Therapies
2020 - Springer Science+Business Media | Pediatric Radiology
Nelly B.M. Posada, Marcus A. Guimarães, Diego S. Padilha, Jackson A. L. C. Resende, Roberto B. Faria, Maurício Lanznaster, Roberto Salgado Amado, Marciela Scarpellini,
Abstract Three mononuclear copper(II) complexes (C1–C3) containing the ligand 2-(2-aminomethyl)pyridine (aep) and some modifications of it were designed to get insights on the influence of pendant second sphere groups (thiophene and benzene) on their physicochemical and catalytic properties. Complexes C1–C3 were synthesized reacting copper(II) chloride with the precursor ligand LP1, N-(2-(pyridin-2-yl)ethylidene)-1-(thiophen-2-yl)methanamine, and the ligands L2, 2-(pyridin-2-yl)-N-(thiophen-2-y-lmethyl) ...
Tópico(s): Magnetism in coordination complexes
2017 - Elsevier BV | Polyhedron
Produção Nacional
Revisado por pares
Marco Antonio Ferraz Nogueira Filho, Elias Carvalho Padilha, Michel Leandro de Campos, Diego Vinícius de Pontes Machado, Marcelo Gomes Davanço, Kelly Chrystina Pestana, Chung Man Chin, Rosângela Gonçalves Peccinini,
The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active against the parasite T. cruzi amastigotes. These advantages make the prodrug a possible therapeutic alternative for the treatment of both acute and the chronic phase of Chagas disease. However, the knowledge of pharmacokinetic profile is crucial to evaluate the feasibility of a new drug. ...
Tópico(s): Helminth infection and control
2013 - Bentham Science Publishers | Drug Metabolism Letters
Produção Nacional
Revisado por pares
Darlene dos Santos Daltro, Alessandro Haiduck Padilha, Marcos Vinícius Gualberto Barbosa da Silva, Elisandra Lurdes Kern, Diego Charles de Almeida Santos, J. C. do C. Panetto, L.T. Gama, Jaime Araújo Cobuci,
ABSTRACT Linear and nonlinear models were used to evaluate the effect of heterosis on the components of the lactation curves of different crossbred groups of cows from Girolando cattle. Data consisted of 233,587 test-day milk yield records from 33,995 primiparous cows from 1998 and 2014. The Wood's linear model (WDlin), Wood's nonlinear model (WDnlin), Wilmink's model (WL) and Ali and Schaeffer's model (ASH) were used to estimate individual peak milk yield (PY), day of peak milk yield (PT), 305-day milk ...
Tópico(s): Genetic Mapping and Diversity in Plants and Animals
2019 - Taylor & Francis | Journal of Applied Animal Research
Produção Nacional
Revisado por pares
Gersiel Nascimento de Oliveira Júnior, Karla Fabiana Goessler, Jhonnatan Vasconcelos Pereira Santos, Alisson Padilha de Lima, Rafael Genário, Carlos Merege-Filho, Diego Augusto Nunes Rezende, Anthony Damiot, Roberto de Cleva, Marco Aurélio Santo, Hamilton Roschel, Bruno Gualano,
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Tópico(s): Cardiac Health and Mental Health
2021 - Springer Science+Business Media | Obesity Surgery
Produção Nacional
Manuela Corrêa de Castro Padilha, L. E. Vicente, José Alexandre Melo Demattê, Daniel Loebmann, Andréa Koga-Vicente, Diego Fernando Urbina Salazar, Clécia Cristina Barbosa Guimarães,
Quantification of soil organic carbon (SOC) is a low-cost and necessary practice to meet increasing agricultural demands. Studies show that remote sensing (RS) is important for SOC prediction and its use has become crucial in agricultural management. In this study, a Multiple Linear Regression (MLR) model was constructed to predict SOC in a site in Piracicaba, São Paulo, Brazil. As predictor variables, we used the optical-satellite data of OLI/Landsat-8 sensor (bands 5 and 7, specifically), clay concentration, ...
Tópico(s): Remote Sensing in Agriculture
2020 - Elsevier BV | Geoderma Regional
Produção Nacional
Revisado por pares
Diego S. Padilha, Yan F. Santos, Letícia C. Giacomin, Frederico A.V. Castro, Marcos D. Pereira, Alexandre B. Rocha, Jackson A. L. C. Resende, Marciela Scarpellini,
Tópico(s): Metal-Organic Frameworks: Synthesis and Applications
2016 - Elsevier BV | Polyhedron
Produção Nacional
Revisado por pares
Diego Trevisan Brunelli, Vinícius Boldrini, Ivan Luiz Padilha Bonfante, Renata Garbellini Duft, Keryma Chaves da Silva Mateus, Leonardo Costa, Mara Patrícia Traina Chacon‐Mikahil, Ana Teixeira, Alessandro S. Farias, Cláudia Regina Cavaglieri,
Recently, it has been argued that obesity leads to a chronic pro-inflammatory state that can accelerate immunosenescence, predisposing to the early acquisition of an immune risk profile and health problems related to immunity in adulthood. In this sense, the present study aimed to verify, in circulating leukocytes, the gene expression of markers related to early immunosenescence associated with obesity and its possible relationships with the physical fitness in obese adults with type 2 diabetes ...
Tópico(s): Exercise and Physiological Responses
2022 - Frontiers Media | Frontiers in Immunology
Produção Nacional
Revisado por pares
Tiane Ferreira de Castro, Antônio Sérgio Varela, Francine Ferreira Padilha, Daniela Droppa-Almeida, Graciela Quintana Saalfeld, Diego Martins Pires, Jéssica Ribeiro Pereira, Carine Dahl Corcini, Elton Pinto Colares,
Tópico(s): Microplastics and Plastic Pollution
2019 - Springer Science+Business Media | Environmental Science and Pollution Research
Produção Nacional
Revisado por pares
Tiane Ferreira de Castro, Graciela Quintana Saalfeld, Antônio Sérgio Varela, Francine Ferreira Padilha, Klebson Silva Santos, Diego Martins Pires, Jéssica Ribeiro Pereira, Carine Dahl Corcini, Elton Pinto Colares,
The present study aims to evaluate the influence of triphenyltin (TPT) exposure on reproductive physiology on Calomys laucha species, since this species inhabits regions susceptible to exposure to this contaminant. Animals exposed to the highest dose (10.0 mg/kg) presented signs of severe intoxication in only 7 days of exposure, demonstrating a higher sensitivity of this species to triphenyltin. The 10.0 mg TPT/kg dose was analyzed separately for short-term exposure and results suggest that exposure ...
Tópico(s): Microplastics and Plastic Pollution
2018 - Elsevier BV | Chemosphere
Produção Nacional
Revisado por pares
Ana Paula D’Alincourt Carvalho-Assef, Polyana Silva Pereira, Rodolpho Mattos Albano, Gabriela Casemiro Berião, Carolina Padilha Tavares, Thiago Pavoni Gomes Chagas, Elizabeth Andrade Marques, Loeci Natalina Timm, Renato C. F. da Silva, Diego R. Falci, Marise Dutra Asensi,
After the first description of NDM-1 carbapenemase in a Providencia rettgeri isolate in Brazil in February 2013 ([1][1]), the public hospital where this isolate was recovered began an active surveillance in search of asymptomatic carriers and in the hospital environment. Furthermore, a retrospective
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2014 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Produção Nacional
Revisado por pares
Luiz Paulo Nogueira Aires, Beatriz Gasser, Priscila Silva, Priscila Del Aguila Da Silva, Marcus Vinícius Silveira, Rafael Kretzer Carneiro, Diego IwaoYamada, Luciana Cristina Padilha‐Nakaghi, Ricardo Andrés Ramírez Uscátegui, Stefano Spada, Marco Russo, Marcus Antônio Rossi Feliciano,
The aim was to sonographically evaluate the reproductive tract of bitches during the follicular phase of the estrous cycle using High Density (HD) ultrasonic techniques. Females (n = 8) were evaluated at five different times throughout the follicular phase, as determined by vaginal cytology and blood progesterone concentrations. Ultrasonic exams were performed using the ACUSON S2000/SIEMENS device utilizing a multifrequency HD transducer (5.5–18 MHz). Videos of the ovaries were obtained and recordings ...
Tópico(s): Reproductive Biology and Fertility
2021 - Elsevier BV | Animal Reproduction Science
Produção Nacional
Revisado por pares
João Luiz de Lemos Padilha Pitta, Matheus Filgueira Bezerra, Diego Leandro Reis da Silva Fernandes, Tessa de Block, Ane de Souza Novaes, Alzira Maria Paiva de Almeida, Antônio Mauro Rezende,
Yersinia pestis, the etiological agent of the plague, is considered a genetically homogeneous species. Brazil is currently in a period of epidemiological silence but plague antibodies are still detected in sentinel animals, suggesting disease activity in the sylvatic cycle. The present study deployed an in silico approach to analyze virulence factors among 407 Brazilian genomes of Y. pestis belonging to the Fiocruz Collection (1966–1997). The pangenome analysis associated several known virulence ...
Tópico(s): Bacillus and Francisella bacterial research
2023 - Multidisciplinary Digital Publishing Institute | Pathogens
Produção Nacional
Revisado por pares
Diego Augusto Campeol, Cristian Padilha Fontoura, Melissa Machado Rodrigues, César Aguzzoli,
Nitinol is an excellent biomaterial amongst smart materials, which have shape and form memory effects and superelasticity, and is mainly used as orthodontic wire and coronary stent. One of the associated drawbacks, however, is nickel release into bloodstream, which can achieve critical levels. In this work, F2063 Nitinol wire was plasma-oxidized in order to obtain a TiO2 protective layer ranging from 50 to 80 nm, which helps blocking nickel release and enhances corrosion properties, thus avoiding ...
Tópico(s): Titanium Alloys Microstructure and Properties
2019 - Elsevier BV | Vacuum
Produção Nacional
Revisado por pares
Diego Trevisan Brunelli, Enrico Antonio Rautenberg Finardi, Ivan Luiz Padilha Bonfante, Arthur Fernandes Gáspari, Amanda Veiga Sardeli, Thiago Mattos Frota de Souza, Mara Patrícia Traina Chacon‐Mikahil, Cláudia Regina Cavaglieri,
The objective of the present study was to verify the energy expenditure (EE), energy system contributions and autonomic control during and after an acute low-load or high-load resistance training (RT) protocol to momentary failure (MF) in young adults. Eleven young men (22 ± 3 yrs, 71.8 ± 7.7 kg; 1.75 ± 0.06 m) underwent a randomized crossover design of three knee extension acute protocols: a low-load RT [30% of their maximal strength (1RM); RT30] or a high-load RT (80% of 1RM; RT80) protocol, with all sets ...
Tópico(s): Cardiovascular Effects of Exercise
2019 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Krista M. Kulesa, Diego S. Padilha, Bishnu Thapa, Shivnath Mazumder, Yaroslav Losovyj, H. Bernhard Schlegel, Marciela Scarpellini, Cláudio N. Verani,
The prototypical drug carrier [CoII(L1)Cl]PF6 (1), where L1 is a tripodal amine bound to pyridine and methyl-imidazoles, had its electrocatalytic water splitting activity studied under different pH conditions. This species contains a high-spin 3d7 CoII metal center, and is capable of generating both H2 from water reduction and O2 from water oxidation. Turnover numbers reach 390 after 3 h for water reduction. Initial water oxidation activity is molecular, with TONs of 71 at pH 7 and 103 at pH 11.5. ...
Tópico(s): Advanced battery technologies research
2023 - Elsevier BV | Journal of Inorganic Biochemistry
Produção Nacional
Revisado por pares
Sérgio F. Fonseca, Nathalia B. Padilha, Samuel Thurow, Juliano A. Roehrs, Lucielli Savegnago, Maurice Neto de Souza, Mariana G. Fronza, Tiago Collares, Julieti H. Buss, Fabiana K. Seixas, Diego Alves, Eder J. Lenardão,
Herein we report the use of ultrasonic irradiation (US) in the synthesis of six new semi-synthetic selenium-containing chrysin derivatives by a simple and effective methodology utilizing CuI as catalyst, in good to excellent yields (60-89%). It was observed that US accelerates the reaction compared to conventional heating with excellent selectivity for diselenylated products. Compounds were tested for their antioxidant and anticancer activities in vitro and it was observed that the presence of selenium ...
Tópico(s): Organoselenium and organotellurium chemistry
2017 - Elsevier BV | Ultrasonics Sonochemistry
Produção Nacional
Revisado por pares
Ivan Luiz Padilha Bonfante, Milena Monfort‐Pires, Renata Garbellini Duft, Keryma Chaves da Silva Mateus, José Carlos de Lima Júnior, Joice Cristina dos Santos Trombeta, Enrico Antonio Rautenberg Finardi, Diego Trevisan Brunelli, Joseane Morari, Jéssica Aparecida Barbosa de Lima, Maria Luisa Bellotto, Thiago Matos Ferreira de Araújo, Celso Darío Ramos, Mara Patrícia Traina Chacon‐Mikahil, Lı́cio A. Velloso, Cláudia Regina Cavaglieri,
Tópico(s): Exercise and Physiological Responses
2022 - Springer Nature | International Journal of Obesity
Produção Nacional
Revisado por pares
Paula Tâmara Vieira Teixeira Pereira, Andréa Dias Reis, Surama do Carmo Sousa Silva, Larissa de Lourdes Padilha Serra, Richard Diego Leite, Mayara da Silva, Mônica Virginia Viégas Lima-Aragão, Flávia Raquel Fernandes do Nascimento, João Batista Santos Garcia, Rosane Nassar Meireles Guerra,
This study investigated the effects of babassu and coconut oil supplementation in breast cancer patients. This randomized clinical trial included 60 patients divided into three groups: untreated control group (CG), babassu oil group (BG), and coconut oil group (COG). Fatigue, quality of life, depression, tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and salivary IgA were analysed before and after 12 weeks of supplementation. Babassu supplementation decreased fatigue and improved quality ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2020 - Elsevier BV | Journal of Functional Foods
Liena kalline Vitor Camboim, William R. Tebar, Camila de Souza Padilha, Diego Giulliano Destro Christófaro, David Ohara,
Avaliar a associação de comportamentos de movimento de 24 horas com ansiedade em universitários durante a pandemia. Os resultados transversais baseiam-se em 87 estudantes (idade média = 26,6±6,5 anos, 72,7% do sexo feminino). Foi preenchido um questionário online sobre dados sociodemográficos, ansiedade (Inventário de Ansiedade Traço-Estado-Traço), qualidade do sono (PSQI) e comportamento sedentário (CS). Utilizou-se, durante sete dias, dois acelerômetros da marca ActiGraph modelo wGT3X-BT para medir ...
Tópico(s): Healthcare during COVID-19 Pandemic
2024 - UNIVERSIDADE ESTADUAL DO SUDOESTE DA BAHIA | Saúde com
Produção Nacional
Revisado por pares
Diego Trevisan Brunelli, Mara Patrícia Traina Chacon‐Mikahil, Arthur Fernandes Gáspari, Wendell Arthur Lopes, Valéria Bonganha, Ivan Luiz Padilha Bonfante, Maria Luisa Bellotto, Cleiton Augusto Libardi, Cláudia Regina Cavaglieri,
Purpose We investigated the effects of 24 wk of combined training on proinflammatory and anti-inflammatory markers associated with obesity in obese middle-age men. Methods Thirty obese men (48.73 ± 1.04 yr; body mass index, 31.00 ± 0.29 kg·m−2) underwent 24 wk of combined training [CT (N = 17), aerobic (50%–85% of V˙O2peak) and resistance (6–10 maximum repetition [RM]) training)] three times per week, 60 min per session, or a control group (N = 13). Anthropometric measures, maximal strength for leg press and bench ...
Tópico(s): Adipose Tissue and Metabolism
2015 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Produção Nacional
Revisado por pares
Elizangela Ambrósio, Diego L. Lucca, Maicon H.B. Garcia, Maísa Tatiane Ferreira de Souza, Thábata K.F. de S. Freitas, Renata Padilha de Souza, Jesuí V. Visentainer, Juliana Carla Garcia,
This study reports on the investigation of the photodegradation of biodiesel (B100) in contact with water using TiO2/H2O2. The TiO2 was characterized by X-ray diffraction analysis (XRD), pH point of zero charge (pHpzc) and textural analysis. The results of the experiments were fitted to a quadratic polynomial model developed using response surface methodology (RSM) to optimize the parameters. Using the three factors, three levels, and the Box-Behnken design of experiment technique, 15 sets of experiments ...
Tópico(s): Water Quality Monitoring and Analysis
2017 - Elsevier BV | The Science of The Total Environment
Produção Nacional
Revisado por pares
Fabiana Lúcia André Padilha, Helen Colbachini, Sofia Dressel Ramos, Laura Reisfeld, Paloma Canedo Henrique, Roberta Ferreira Leite, João Diego de Agostini Losano, M. Nichi, Raphaela Gabrielle Brito Sousa, Rafael Caprioli Gutierrez, Pedro Nacib Jorge‐Neto, Cristiane Schilbach Pizzutto,
Tópico(s): Fish Biology and Ecology Studies
2021 - Springer Science+Business Media | Environmental Biology of Fishes
Produção Nacional
Rove Chishman, Aline Nardes dos Santos, Diego Spader de Souza, João Gabriel Padilha,
Resumo : O objetivo deste trabalho é apresentar o papel do concordanceador Sketch Engine no desenvolvimento do Field – Dicionário de Expressões do Futebol, um recurso lexicográfico trilíngue baseado na noção de Frame Semântico e em corpora linguísticos. Aqui são apresentadas algumas considerações concernentes não apenas aos recursos disponíveis na ferramenta mas também às análises realizadas por meio desse programa. Na segunda seção, a Semântica de Frames , teoria proposta por Fillmore (1982, 1985), é ...
Tópico(s): Natural Language Processing Techniques
2015 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Revista de Estudos da Linguagem